tolfenamic-acid and cinnamyl-alcohol

tolfenamic-acid has been researched along with cinnamyl-alcohol* in 1 studies

Other Studies

1 other study(ies) available for tolfenamic-acid and cinnamyl-alcohol

ArticleYear
Esters of some non-steroidal anti-inflammatory drugs with cinnamyl alcohol are potent lipoxygenase inhibitors with enhanced anti-inflammatory activity.
    Bioorganic & medicinal chemistry letters, 2015, Nov-15, Volume: 25, Issue:22

    Novel esters of non steroidal anti-inflammatory drugs, α-lipoic acid and indol-3-acetic acid with cinnamyl alcohol were synthesised by a straightforward method and at high yields (60-98%). They reduced acute inflammation more than the parent acids and are potent inhibitors of soybean lipoxygenase. Selected structures decreased plasma lipidemic indices in Triton-induced hyperlipidemia to rats. Therefore, the synthesised compounds may add to the current knowledge about agents acting against various inflammatory disorders.

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cinnamates; Edema; Esters; Glycine max; Hyperlipidemias; Indoleacetic Acids; Lipoxygenase Inhibitors; Polyethylene Glycols; Propanols; Propionates; Rats; Thioctic Acid

2015