Page last updated: 2024-08-16

tolbutamide and sulfadiazine

tolbutamide has been researched along with sulfadiazine in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19908 (40.00)18.7374
1990's0 (0.00)18.2507
2000's6 (30.00)29.6817
2010's6 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Carrupt, PA; Martel, S; Ottaviani, G1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Harris, AW; Wray, HL1
Wosilait, WD1
Jacker, HJ1
Büttner, H; Portwich, F1
Bergmann, F; Gutman, Y; Zerachia, A1
Brown, JD; Cox, CP; Stone, DB1
Brown, JD; Stone, DB1
CHRISTENSEN, LK; HANSEN, JM; KRISTENSEN, M1

Reviews

2 review(s) available for tolbutamide and sulfadiazine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Antidiabetics. 42].
    Pharmazeutische Praxis, 1969, Volume: 12

    Topics: Adolescent; Adult; Aged; Biguanides; Carbutamide; Child; Child, Preschool; Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucosamine; Humans; Hypoglycemic Agents; Infant; Insulin; Insulin, Long-Acting; Middle Aged; Oxazoles; Plants, Medicinal; Pyrazoles; Quinolines; Sulfadiazine; Sulfathiazoles; Tolbutamide; Triazines; Urea

1969

Trials

1 trial(s) available for tolbutamide and sulfadiazine

ArticleYear
Effect of sulfonylurea drugs on plasma free fatty acid and blood glucose concentrations in man.
    Diabetes, 1966, Volume: 15, Issue:5

    Topics: Acetohexamide; Adipose Tissue; Animals; Blood Glucose; Diabetes Mellitus; Fasting; Fatty Acids; Glycerol; Humans; In Vitro Techniques; Lipid Metabolism; Phenformin; Placebos; Rats; Sulfadiazine; Tolbutamide

1966

Other Studies

17 other study(ies) available for tolbutamide and sulfadiazine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities.
    Journal of medicinal chemistry, 2007, Feb-22, Volume: 50, Issue:4

    Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Adenosine 3', 5'-monophosphate-dependent protein kinase in adipose tissue: inhibition by tolbutamide.
    Biochemical and biophysical research communications, 1973, Jul-02, Volume: 53, Issue:1

    Topics: Adipose Tissue; Animals; Cyclic AMP; Epididymis; Male; Phosphorus Isotopes; Protein Kinase Inhibitors; Rats; Sulfadiazine; Sulfonic Acids; Tolbutamide; Toluene; Urea

1973
An analysis of the effect of hypoalbuminemia on the amount of free drug in plasma for drugs bound at two sets of sites.
    Research communications in chemical pathology and pharmacology, 1974, Volume: 9, Issue:4

    Topics: Binding Sites; Carbenoxolone; Chlorpromazine; Chlorpropamide; Computers; Dose-Response Relationship, Drug; Humans; Iopanoic Acid; Pharmaceutical Preparations; Phenylbutazone; Protein Binding; Quinidine; Salicylates; Serum Albumin; Sulfadiazine; Tolbutamide

1974
[Competition phenomena in the binding of drugs to albumin].
    Klinische Wochenschrift, 1967, Mar-01, Volume: 45, Issue:5

    Topics: Drug Synergism; Hydrogen-Ion Concentration; Protein Binding; Serum Albumin; Serum Albumin, Bovine; Sulfadiazine; Tolbutamide; Ultracentrifugation

1967
The antidipsic effect of sulphonamides implanted in the hypothalamus of rats.
    Experientia, 1968, Apr-15, Volume: 24, Issue:4

    Topics: Acetazolamide; Animals; Chlorothiazide; Chlorpropamide; Depression, Chemical; Drinking Behavior; Hydrochlorothiazide; Hypothalamo-Hypophyseal System; Hypothalamus; Rats; Sulfadiazine; Sulfonamides; Thirst; Tolbutamide; Vasopressins; Water

1968
Effect of tolbutamide and phenformin on lipolysis in adipose tissue in vitro.
    The American journal of physiology, 1966, Volume: 210, Issue:1

    Topics: Adipose Tissue; Animals; Fatty Acids; Glycerol; In Vitro Techniques; Phenformin; Rats; Sulfadiazine; Tolbutamide

1966
SULPHAPHENAZOLE-INDUCED HYPOGLYCAEMIC ATTACKS IN TOLBUTAMIDE-TREATED DIABETICS.
    Lancet (London, England), 1963, Dec-21, Volume: 2, Issue:7321

    Topics: Aged; Diabetes Mellitus; Geriatrics; Humans; Hypoglycemia; Hypoglycemic Agents; Phenylbutazone; Sulfadiazine; Sulfadimethoxine; Sulfaphenazole; Tolbutamide

1963