tolbutamide has been researched along with piperidines in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 7 (58.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rynbrandt, RH; Schmidt, FL | 1 |
| Kruseman, AC; Menheere, PP; Müller, PG; Nijst, L; Sels, JP; Wolffenbuttel, BH | 1 |
| Ashcroft, FM; Carr, RD; Christensen, IT; Hansen, AM; Hansen, JB; Wahl, P | 1 |
| Ashcroft, SJ; Mikhailov, MV; Mikhailova, EA | 1 |
| Bae, JH; Cho, CH; Han, J; Jang, BC; Kim, SP; Kim, SS; Lee, HY; Lim, JG; Park, JW; Park, MJ; Song, DK; Suh, SI; Yun, JE | 1 |
| Chung, KK; Freestone, PS; Lipski, J | 1 |
| Abdelmoneim, AS; Brocks, DR; Hasenbank, SE; Light, PE; Seubert, JM; Simpson, SH | 1 |
| Andersson, C; Fosbøl, EL; Gislason, G; Køber, L; Mogensen, UM; Scheller, NM; Schramm, TK; Torp-Pedersen, C; Vaag, A | 1 |
| Govindarajulu, B; Rangasamy, M; Thappali, S; Vakkalanka, S; Veeraraghavan, S; Viswanadha, S | 1 |
| Gillen, M; Kerr, B; Lee, C; Shen, Z; Valdez, S; Wilson, D; Yang, C | 1 |
| Gaudette, F; Huguet, J; Michaud, V; Turgeon, J | 1 |
| Kansra, V; Lu, S; Powers, D; Wang, J; Wang, X; Zhang, ZY | 1 |
1 review(s) available for tolbutamide and piperidines
| Article | Year |
|---|---|
Variations in tissue selectivity amongst insulin secretagogues: a systematic review.
Topics: Animals; ATP-Binding Cassette Transporters; Carbamates; Cardiovascular Diseases; Cricetinae; Cyclohexanes; Diabetes Mellitus, Type 2; Gliclazide; Glipizide; Glyburide; Humans; Hypoglycemic Agents; Ischemic Preconditioning, Myocardial; Isoindoles; Mice; Muscle, Smooth, Vascular; Myocytes, Cardiac; Nateglinide; Phenylalanine; Piperidines; Potassium Channels, Inwardly Rectifying; Rats; Receptors, Drug; Risk Factors; Sulfonylurea Compounds; Sulfonylurea Receptors; Tolbutamide | 2012 |
2 trial(s) available for tolbutamide and piperidines
| Article | Year |
|---|---|
Effects of a new oral hypoglycaemic agent, repaglinide, on metabolic control in sulphonylurea-treated patients with NIDDM.
Topics: Aged; Blood Glucose; Carbamates; Diabetes Mellitus, Type 2; Female; Fructosamine; Gliclazide; Glyburide; Glycated Hemoglobin; Hexosamines; Humans; Hypoglycemic Agents; Lipids; Male; Middle Aged; Piperidines; Tolbutamide | 1993 |
Effects of rolapitant administered orally on the pharmacokinetics of dextromethorphan (CYP2D6), tolbutamide (CYP2C9), omeprazole (CYP2C19), efavirenz (CYP2B6), and repaglinide (CYP2C8) in healthy subjects.
Topics: Administration, Oral; Adolescent; Adult; Alkynes; Antiemetics; Benzoxazines; Carbamates; Cyclopropanes; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Dextromethorphan; Drug Combinations; Drug Interactions; Female; Healthy Volunteers; Humans; Male; Middle Aged; Molecular Probes; Neurokinin-1 Receptor Antagonists; Omeprazole; Piperidines; Spiro Compounds; Tolbutamide; Young Adult | 2019 |
9 other study(ies) available for tolbutamide and piperidines
| Article | Year |
|---|---|
Cis-1-[(2-piperidinocyclohexyl)carbonyl]-piperidine and related compounds. Oral hypoglycemic agents.
Topics: Animals; Blood Glucose; Chemical Phenomena; Chemistry; Hypoglycemic Agents; Models, Structural; Piperidines; Rats; Tolbutamide | 1971 |
Differential interactions of nateglinide and repaglinide on the human beta-cell sulphonylurea receptor 1.
Topics: ATP-Binding Cassette Transporters; Binding, Competitive; Carbamates; Cell Line; Cyclohexanes; Drug Interactions; Electrophysiology; Humans; Islets of Langerhans; Nateglinide; Phenylalanine; Piperidines; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Sulfonylurea Receptors; Tolbutamide | 2002 |
A novel simple method for the investigation of drug binding to the K(ATP) channel sulfonylurea receptor.
Topics: Animals; ATP-Binding Cassette Transporters; Carbamates; Gliclazide; Glyburide; Hypoglycemic Agents; Kinetics; Piperidines; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Binding; Rats; Receptors, Drug; Spodoptera; Sulfonylurea Receptors; Tolbutamide | 2002 |
Taurine block of cloned ATP-sensitive K+ channels with different sulfonylurea receptor subunits expressed in Xenopus laevis oocytes.
Topics: Animals; ATP-Binding Cassette Transporters; Carbamates; Drug Interactions; Female; Gene Expression; Gliclazide; Glyburide; Hypoglycemic Agents; Membrane Proteins; Mice; Oocytes; Piperidines; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Subunits; Rats; Receptors, Drug; Sulfonylurea Receptors; Taurine; Tolbutamide; Xenopus laevis | 2004 |
Expression and functional properties of TRPM2 channels in dopaminergic neurons of the substantia nigra of the rat.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Biophysics; Calcium; Clusterin; Dopaminergic Neurons; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Glyburide; Hydrogen Peroxide; In Vitro Techniques; Isoquinolines; Membrane Potentials; Oxidants; Patch-Clamp Techniques; Piperidines; Potassium Channel Blockers; Rats; Reactive Oxygen Species; RNA, Messenger; Substantia Nigra; Tetraethylammonium; Tolbutamide; Tyrosine 3-Monooxygenase | 2011 |
Metformin in combination with various insulin secretagogues in type 2 diabetes and associated risk of cardiovascular morbidity and mortality--a retrospective nationwide study.
Topics: Aged; Carbamates; Cardiovascular Diseases; Denmark; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Gliclazide; Glipizide; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Morbidity; Myocardial Infarction; Piperidines; Registries; Retrospective Studies; Risk Factors; Stroke; Sulfonylurea Compounds; Tolbutamide | 2015 |
Simultaneous quantification of lenalidomide, ibrutinib and its active metabolite PCI-45227 in rat plasma by LC-MS/MS: application to a pharmacokinetic study.
Topics: Adenine; Animals; Calibration; Chromatography, High Pressure Liquid; Drug Stability; Lenalidomide; Liquid-Liquid Extraction; Male; Piperidines; Plasma; Pyrazoles; Pyrimidines; Rats; Rats, Wistar; Reproducibility of Results; Tandem Mass Spectrometry; Thalidomide; Tolbutamide | 2015 |
Evaluation of Pharmacokinetic Interactions Between Lesinurad, a New Selective Urate Reabsorption Inhibitor, and CYP Enzyme Substrates Sildenafil, Amlodipine, Tolbutamide, and Repaglinide.
Topics: Adult; Amlodipine; Area Under Curve; Carbamates; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation; Healthy Volunteers; Humans; In Vitro Techniques; Male; Middle Aged; Piperidines; Sildenafil Citrate; Thioglycolates; Tolbutamide; Triazoles; Young Adult | 2017 |
Development and validation of probe drug cocktails for the characterization of CYP450-mediated metabolism by human heart microsomes.
Topics: Bupropion; Butyrophenones; Carbamates; Chlorzoxazone; Cytochrome P-450 Enzyme System; Drug Evaluation, Preclinical; Ethanolamines; Humans; Lauric Acids; Microsomes; Midazolam; Myocardium; Oxazines; Piperidines; Tolbutamide | 2019 |