Page last updated: 2024-08-16

tolbutamide and phenformin

tolbutamide has been researched along with phenformin in 207 studies

Research

Studies (207)

Timeframe	Studies, this research(%)	All Research%
pre-1990	195 (94.20)	18.7374
1990's	5 (2.42)	18.2507
2000's	1 (0.48)	29.6817
2010's	6 (2.90)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Märki, F; Rihs, G; Schweizer, EH	1
Dietrich, H; Lehmann, C; Märki, F; Schweizer, EH	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Rümke, CL	1
Fuller, JH; Jarrett, RJ; Keen, H	1
Gregory, DR	1
Jain, AK; McMahon, FG; Ryan, JR	1
Bressler, R; Shen, SW	2
Friedberg, SJ; Kudzma, DJ	1
Bradley, RF; Gleason, RE; Graham, CA; Soeldner, JS; Tan, MH	1
Kolata, GB	1
Bloom, A; Bulpitt, CJ; Shaw, KM	1
Di Saverio, S; Roncaia, R; Torri, A; Zanni, A	1
Bartosiewicz, W; Lao, B	1
Milman, HA; Peckham, JC; Tarone, RE; Ward, JM	1
Chempakam, B; Kurup, PA	4
Chamberlain, J; Hill, HM	1
Kaffarnik, H; Schneider, J	1
Bandisode, MS; Boshell, BR	1
Keen, H	1
Shagan, BP	1
Bennett, MA; Fitzgerald, MG; Malins, JM; Pentecost, BL; Soler, NG	1
Prout, TE	3
Bohannon, NV; Dunphy, TW; Forsham, PH; Gerich, JE; Kane, JP; Karam, JH; Lorenzi, M; Tsalikian, E	1
Ennis, G	1
Davidson, JK	1
Touber, JL	1
Scoville, AB	2
Palmer, JP; Williams, RH	1
Moser, RH	1
Ahmed, HM	1
Brearley, BF	1
de Nobel, E; van 't Laar, A	1
Bierman, EL	1
Hussin, AH; Skett, P	1
Bartosiewicz, W; Czyzyk, A; Lao, B; Orłowska, K; Szczepanik, Z	1
Kilo, C; Williamson, JR	1
Burns, H; Raskin, P; Siperstein, MD	1
Hodgins, DS; Kuo, JF; Kuo, WN	1
Johansen, K; Lundbaek, K	1
Lee, CT; Schless, GL	1
Butterfield, WJ; Whichelow, MJ	1
de Baere, H; de Leeuw, I; Decraene, P; Lemmens, P; Verhaegen, H	1
Goodner, CJ; Ogilvie, JT	1
Mughini, L; Polosa, P	1
Beringer, A	1
Kurup, PA; Malathi, K	1
Kurup, PA; Prasannan, K	3
Dalidowicz, JE; McDonald, HJ	1
Brown, JD; Stone, DB	2
Brown, JD; Steele, AA; Stone, DB	1
Augusti, KT; Kurup, PA	1
Lasseter, KC; Levey, GS; McCarthy, JS; Palmer, RF	1
Lasseter, KC; Levey, GS; Palmer, RF	1
Abdel-Khalek, A; Khayyal, MT; Masri, AM; Saleh, S; Sharat, AA	1
Dempsey, ME	1
Clayman, CB	1
Jounela, AJ; Palva, IP; Pirttiaho, H	1
Bianchi, R; Chin, FT; Rosenbloom, AL	1
Klimt, CR; Knatterud, GL; Meinert, CL; Prout, TE	1
Gray, RH	1
Kirkeby, K	1
Stehling, L	1
Schöffling, K	2
Knowles, HC	1
Cacciari, E; Cicognani, A; Collina, A; Pirazzoli, P; Tassoni, P	1
Bloom, A	1
Matz, R	1
Baker, RW; Davis, BH; Ward, JD	1
Kurup, PA; Malathy, K	1
DeLawter, DE; Moss, JM	1
Alpers, DH; Berstein, R; Kelly, J; Kipnis, DM; Permutt, MA; Siegel, BA	1
Crawford, D; Elashoff, R; Feldman, R; Glass, A	1
Augusti, KT; Prasannan, K	1
Folling, I	1
Poffenbarger, PL	1
Chhetri, MK	1
Jackson, WP; Vinik, AI	1
Lopis, S; Schneider, T	1
Kadota, I	1
Bricker, LA; Mintz, DH	1
Klimt, CR; Knatterud, GL; Martin, DB; Meinert, CL; Osborne, RK	1
Salsburg, DS	1
Gershberg, H; Hecht, A; Hulse, M; Javier, Z	1
Bacon, GE; Parkhurst, RD	1
Clarke, BF; Duncan, LJ	1
Pirart, J	1
Bloom, A; Tomkins, AM	1
Brush, JS; Burghen, GA; Kitabchi, AE	1
Elkeles, RS	1
Seltzer, HS	2
Goetz, FC	1
Harris, EL	1
Bianchini, P; Bramanti, G; De Fina, V; Dell'Omodarme, G	1
Ahuja, MM; Kumar, V	1
Gulati, OD; Shah, CP; Venugopal, K	1
Boshell, BR; McAdams, GL; Roddam, RF	1
Chakrabarti, R; Evans, J; Fearnley, GR; Hocking, ED	1
Meinert, CL; Schwartz, TB	1
Alger, CR; Castelazo Ayala, L; Flores, HV; Navarrete, VN; Torres, IH	1
Boyns, AR; Mahler, RF; Pearce, N	1
Camerini-Dávalos, RA; De Lellis, RH; Jimenez, JA; Oppermann, W	1
Crawford, D; Feldman, R	1
Chan, SS; Fain, JN	1
Cabezas Cerrato, J; Fernández-Cruz, A	1
McDonald, HJ; Murray, HL	1
Saad, SF	1
Dhirawani, MK; Doshi, JC; Patel, JC	1
Chamnong, V; Malhotra, SC; Razdan, MK	1
Beaser, SB; Howard, FM	1
Gulati, OD; Patel, DG	1
DeChatelet, LR; McDonald, HJ	2
Fineberg, SK	2
Johansen, K	1
Abelove, WA; Echenique, R	1
Whichelow, MJ	1
Gershberg, H; Hulse, M	1
Fearnley, GR	1
Goodman, JI	2
Clarke, BF; Duncan, LJ; Munro, JF	1
Brown, JD; Cox, CP; Stone, DB	1
Ellenberg, M	1
Mirsky, S; Schaefer, LE; Schwartz, MJ	2
Duncan, GG; Duncan, TG	1
Roberts, HJ	1
Gershbein, LL	1
Fawthrop, H; Tutwiler, GF	1
Tattersall, RB	1
Eichelbaum, M	1
Kilo, C; Miller, JP; Williamson, JR	1
Grewal, RS; Kaul, CL; Talwalker, PK	1
Anton, AH; Berk, AI	1
Melander, A	2
Lopez-Liuchi, JV; Meier, CA	1
Born, RC	1
Bethel, MA; Feinglos, MN	1
CARTER, NW; MADISON, LL; UNGER, RH	1
ANDREU-KERN, F; CREUTZFELDT, W; SOELING, HD; WERCHAU, H	1
BUSTOS FERNANDEZ, L; DE PAULA, A; JADZINSKY, MN; NUSIMOVICH, B; POGORELSKY, C	1
SADOW, HS	1
COLWELL, AR; WILKS, HM	1
CALVERT, DN	1
BRADLEY, RF; KRALL, LP	1
EZRIN, C	1
DEROETTH, A; PEI, YF	1
NABARRO, JD	1
BURNS, FH	1
DENEUMANN, PS	1
POULSEN, JE	1
GRAUPNER, K; WIEZOREK, WD	1
BEASER, SB	1
BUTTERFIELD, WJ; JARRETT, RJ	1
TRANQUADA, RE	1
SZANTO, S	1
PADFIELD, CJ	1
WELLER, C	1
CAMERINI D AVALOS, RA; KRALL, LP; LOZANO CASTANEDA, O; MARBLE, A	1
CHAKRABARTI, R; FEARNLEY, GR	2
CANAANI, Z; SCHIFFMAN, A	1
HEISIG, N	1
ARNOLD, CR; LAUENER, RW	1
DELAWTER, DE; GALLAGHER, EJ; MOSS, JM	1
BALL, JE; ELLIOT, W; LUPIN, AM; MARY, CC	1
ROWE, WS	1
BATEMAN, M; BLOOM, A; NEWTON, MA	1
DAVIDSON, MH; KAYE, R	1
WHITEHOUSE, FW	1
FERGUSON, BD	1
BERKOW, JW; RICKETTS, RL	1
WILLIAMS, RH	1
Arsenault, M; Bélanger, PM; Hamelin, BA; Pilote, S; Sharma, A	1

Reviews

17 review(s) available for tolbutamide and phenformin

Article	Year
Clinical pharmacology of oral antidiabetic agents (first of two parts). The New England journal of medicine, 1977, Mar-03, Volume: 296, Issue:9 Topics: Acetohexamide; Administration, Oral; Chemical Phenomena; Chemistry; Chlorpropamide; Diabetes Mellitus; Drug Evaluation; Drug Interactions; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Lipid Metabolism; Phenformin; Secretory Rate; Tolazamide; Tolbutamide	1977
Clinical pharmacology of oral antidiabetic agents (second of two parts). The New England journal of medicine, 1977, Apr-07, Volume: 296, Issue:14 Topics: Administration, Oral; Cardiovascular Diseases; Chlorpropamide; Clinical Trials as Topic; Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Islets of Langerhans; Phenformin; Tolbutamide; Water Intoxication	1977
Antidiabetic agents and vascular events. Journal of clinical pathology. Supplement (Royal College of Pathologists), 1975, Volume: 9 Topics: Adult; Blood Pressure; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus; Humans; Hypoglycemic Agents; Phenformin; Tolbutamide	1975
Diabetes in the elderly patient. The Medical clinics of North America, 1976, Volume: 60, Issue:6 Topics: Acetohexamide; Aged; Chlorpropamide; Diabetes Mellitus; Diet, Diabetic; Energy Intake; Foot; Health Education; Humans; Hygiene; Hypoglycemic Agents; Insulin; Phenformin; Sulfonylurea Compounds; Tolbutamide	1976
Sulfonylureas and the heart. Annual review of medicine, 1974, Volume: 25 Topics: Adenylyl Cyclases; Animals; Cats; Chlorpropamide; Coronary Circulation; Cyclic AMP; Diabetes Mellitus; Enzyme Activation; Heart; Heart Rate; Humans; Kidney; Myocardium; Norepinephrine; Oxygen Consumption; Phenformin; Phosphoric Diester Hydrolases; Rabbits; Rats; Species Specificity; Stimulation, Chemical; Sulfonylurea Compounds; Tolbutamide	1974
Hypoglycemic drugs. Clinical anesthesia, 1974, Volume: 10, Issue:1 Topics: Acetohexamide; Anesthetics; Blood Glucose; Carbohydrate Metabolism; Chlorpropamide; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Neuropathies; Gastrointestinal Diseases; Humans; Hypoglycemic Agents; Insulin; Islets of Langerhans; Pancreas; Phenformin; Tolazamide; Tolbutamide	1974
Oral treatment of diabetes mellitus. Journal of the Indian Medical Association, 1968, May-16, Volume: 50, Issue:10 Topics: Chlorpropamide; Diabetes Mellitus; Humans; Hypoglycemia; Hypoglycemic Agents; Metformin; Phenformin; Sulfonamides; Tolbutamide	1968
[Evaluation of therapy of diabetes mellitus, with special reference to the control of diabetes mellitus with oral antidiabetics]. Nihon rinsho. Japanese journal of clinical medicine, 1969, Volume: 27, Issue:8 Topics: Adult; Animals; Blood Glucose; Cattle; Chlorpropamide; Diabetes Complications; Diabetes Mellitus; Diabetic Retinopathy; Diet Therapy; Female; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Ketone Bodies; Male; Middle Aged; Phenformin; Swine; Tolbutamide	1969
Insulin-independent diabetes mellitus. The Medical clinics of North America, 1971, Volume: 55, Issue:2 Topics: Acetohexamide; Adult; Age Factors; Aged; Basement Membrane; Capillaries; Carbohydrate Metabolism, Inborn Errors; Chlorpropamide; Diabetes Complications; Diabetes Mellitus; Diet, Diabetic; Female; Glucose Tolerance Test; Humans; Hyperlipidemias; Hypoglycemic Agents; Infections; Male; Middle Aged; Muscles; Obesity; Phenformin; Skin Ulcer; Thigh; Tolazamide; Tolbutamide	1971
Metabolic considerations in the treatment of juvenile diabetes mellitus. The Medical clinics of North America, 1969, Volume: 53, Issue:6 Topics: Acid-Base Equilibrium; Amino Acids; Blood Glucose; Child, Preschool; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Coma; Diabetic Ketoacidosis; Diet, Diabetic; Humans; Hyperlipidemias; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Osmolar Concentration; Phenformin; Tolbutamide	1969
Advances in the treatment of diabetes mellitus. The Practitioner, 1971, Volume: 207, Issue:240 Topics: Blood Glucose; Chlorpropamide; Clofibrate; Diabetes Mellitus; Diabetic Coma; Diabetic Ketoacidosis; Diabetic Retinopathy; Diet Therapy; Humans; Hypoglycemia; Insulin; Kidney Transplantation; Lactates; Light Coagulation; Metformin; Methods; Pancreas Transplantation; Phenformin; Pituitary Gland; Renal Dialysis; Sulfonylurea Compounds; Tolbutamide	1971
[25 years of diabetic treatment by oral hypoglycemic agents: successes and failures]. Journees annuelles de diabetologie de l'Hotel-Dieu, 1984 Topics: Aged; Aging; Blood Glucose; Cardiovascular Diseases; Chlorpropamide; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diet, Reducing; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Middle Aged; Phenformin; Sulfonylurea Compounds; Tolbutamide	1984
Review of previous impaired glucose tolerance intervention studies. Diabetic medicine : a journal of the British Diabetic Association, 1996, Volume: 13, Issue:3 Suppl 2 Topics: Diabetes Mellitus, Type 2; Dietary Carbohydrates; Exercise; Follow-Up Studies; Glucose Intolerance; Humans; Hypoglycemic Agents; Incidence; Phenformin; Tolbutamide	1996
Pharmacological intervention: the antidiabetic approach. European journal of clinical investigation, 1998, Volume: 28 Suppl 2 Topics: Controlled Clinical Trials as Topic; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diet, Diabetic; Exercise; Female; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Male; Middle Aged; Phenformin; Tolbutamide	1998
Therapy for type 2 diabetes: where do we stand after the UK prospective diabetes study? European journal of endocrinology, 1999, Volume: 140, Issue:1 Topics: Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Diet Therapy; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Hypoglycemic Agents; Insulin; Metformin; Phenformin; Prospective Studies; Randomized Controlled Trials as Topic; Tolbutamide	1999
ADVANCES IN THE TREATMENT OF DIABETES MELLITUS. The Practitioner, 1963, Volume: 191 Topics: Chlorpropamide; Diabetes Mellitus; Humans; Hypoglycemic Agents; Insulin; Metformin; Phenformin; Tolbutamide	1963
[ORAL DIABETES THERAPY]. Der Internist, 1964, Volume: 5 Topics: Carbutamide; Diabetes Mellitus; Hypoglycemic Agents; Phenformin; Tolbutamide	1964

Trials

38 trial(s) available for tolbutamide and phenformin

Article	Year
Letter: Oral hypoglycaemics in diabetes mellitus. Lancet (London, England), 1975, Nov-01, Volume: 2, Issue:7940 Topics: Adult; Aged; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Mellitus; Humans; Male; Middle Aged; Phenformin; Tolbutamide	1975
Potentiation of hypoglycemic effect of sulfonylureas by halofenate. The New England journal of medicine, 1975, Dec-18, Volume: 293, Issue:25 Topics: Adult; Clinical Trials as Topic; Clofibrate; Diabetes Complications; Diabetes Mellitus; Drug Synergism; Female; Glycolates; Halofenate; Humans; Hyperlipidemias; Hypoglycemic Agents; Lipoproteins, VLDL; Male; Middle Aged; Phenformin; Sulfonylurea Compounds; Tolbutamide; Triglycerides	1975
Clinical pharmacology of oral antidiabetic agents (second of two parts). The New England journal of medicine, 1977, Apr-07, Volume: 296, Issue:14 Topics: Administration, Oral; Cardiovascular Diseases; Chlorpropamide; Clinical Trials as Topic; Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Islets of Langerhans; Phenformin; Tolbutamide; Water Intoxication	1977
Potentiation of hypoglycemic effect of chlorpropamide and phenfromin by halofenate. Diabetes, 1977, Volume: 26, Issue:4 Topics: Blood Glucose; Chlorpropamide; Clinical Trials as Topic; Clofibrate; Diabetes Mellitus; Drug Synergism; Glycolates; Halofenate; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Phenformin; Tolazamide; Tolbutamide	1977
The effects of long-term therapy with oral hypoglycemic agents on the oral glucose tolerance test dynamics in male chemical diabetics. Diabetes, 1977, Volume: 26, Issue:6 Topics: Acetohexamide; Administration, Oral; Adult; Blood Glucose; Chlorpropamide; Cholesterol; Clinical Trials as Topic; Diabetes Mellitus; Double-Blind Method; Female; Follow-Up Studies; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Phenformin; Placebos; Tolbutamide; Triglycerides	1977
Oral anti-diabetic agents: how do they stand after the university group diabetes program (UGDP)? Drug and therapeutics bulletin, 1977, May-13, Volume: 15, Issue:10 Topics: Clinical Trials as Topic; Hypoglycemic Agents; Male; Phenformin; Tolbutamide	1977
Controversy over study of diabetes drugs continues for nearly a decade. Science (New York, N.Y.), 1979, Mar-09, Volume: 203, Issue:4384 Topics: Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Mellitus; Drug Information Services; History, 20th Century; Humans; Hypoglycemic Agents; Jurisprudence; Legislation, Drug; Phenformin; Research Design; Tolbutamide; United States; United States Food and Drug Administration	1979
[Clinical testing of Tolbutaphen in the treatment of adult diabetes]. Zeitschrift fur Allgemeinmedizin, 1975, Jan-20, Volume: 51, Issue:2 Topics: Adult; Clinical Trials as Topic; Diabetes Mellitus; Drug Combinations; Drug Evaluation; Humans; Phenformin; Tolbutamide	1975
Clinical evaluation of a new sulfonylurea in maturity onset diabetes - glipizide (K-4024). Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1976, Volume: 8, Issue:2 Topics: Adult; Aged; Chlorpropamide; Clinical Trials as Topic; Diabetes Mellitus; Dose-Response Relationship, Drug; Drug Evaluation; Drug Therapy, Combination; Follow-Up Studies; Glipizide; Humans; Middle Aged; Phenformin; Sulfonylurea Compounds; Tolbutamide	1976
Antidiabetic agents and vascular events. Journal of clinical pathology. Supplement (Royal College of Pathologists), 1975, Volume: 9 Topics: Adult; Blood Pressure; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus; Humans; Hypoglycemic Agents; Phenformin; Tolbutamide	1975
A progress report on the University Group Diabetes Program. International journal of clinical pharmacology and biopharmacy, 1975, Volume: 12, Issue:1-2 Topics: Clinical Trials as Topic; Diabetes Mellitus; Diabetic Angiopathies; Drug Industry; Health Expenditures; Humans; Iatrogenic Disease; Insulin; Maryland; Myocardial Infarction; Phenformin; Tolbutamide	1975
Report of the Committee for the Assessment of Biometric Aspects of Controlled Trials of Hypoglycemic Agents. JAMA, 1975, Feb-10, Volume: 231, Issue:6 Topics: Administration, Oral; Adult; Aged; Biometry; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Mellitus; Diet, Diabetic; Evaluation Studies as Topic; Female; Follow-Up Studies; Heart; Humans; Hypoglycemic Agents; Male; Middle Aged; Models, Theoretical; Operations Research; Phenformin; Placebos; Sex Factors; Time Factors; Tolbutamide	1975
The University Group Diabetes Program. A study of the effects of hypoglycemic agents on vascular complications in patients with adult-onset diabetes. V. Evaluation of pheniformin therapy. Diabetes, 1975, Volume: 24 Suppl 1 Topics: Aged; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Weight; Cholesterol; Clinical Trials as Topic; Diabetes Complications; Diabetic Angiopathies; Diabetic Retinopathy; Female; Follow-Up Studies; Glucose Tolerance Test; Heart Rate; Humans; Hypertension; Hypoglycemic Agents; Insulin, Long-Acting; Male; Middle Aged; Patient Dropouts; Phenformin; Placebos; Statistics as Topic; Time Factors; Tolbutamide	1975
The FDA and hypoglycemic drugs. JAMA, 1975, May-26, Volume: 232, Issue:8 Topics: Administration, Oral; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Mellitus; Follow-Up Studies; Humans; Hypoglycemic Agents; Legislation, Drug; Phenformin; Placebos; Tolbutamide; United States; United States Food and Drug Administration	1975
[Heart death and oral antidiabetics; the last judgement]. Nederlands tijdschrift voor geneeskunde, 1975, Sep-27, Volume: 119, Issue:39 Topics: Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Mellitus; Drug Evaluation; Female; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Phenformin; Prospective Studies; Tolbutamide; United States	1975
The controversial American University Group Diabetes Study--a look at sulfonylurea and biguanide therapy. Hormone and metabolic research. Supplement series, 1985, Volume: 15 Topics: Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Humans; Male; Patient Compliance; Phenformin; Tolbutamide	1985
Effect of diet, sulphonylureas, and phenformin on peripheral glucose uptake in diabetes and obesity. Lancet (London, England), 1968, Oct-12, Volume: 2, Issue:7572 Topics: Adult; Aged; Blood Flow Velocity; Body Weight; Chlorpropamide; Diabetes Mellitus; Diet Therapy; Female; Glucose; Glucose Tolerance Test; Humans; Male; Middle Aged; Obesity; Phenformin; Tolbutamide	1968
Chemical diabetes mellitus in siblings of children with overt diabetes. Israel journal of medical sciences, 1972, Volume: 8, Issue:6 Topics: Child; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Glucose Tolerance Test; Humans; Hyperinsulinism; Insulin; Phenformin; Placebos; Prediabetic State; Prognosis; Tolbutamide	1972
The UGDP controversy. Clinical trials versus clinical impressions. Diabetes, 1972, Volume: 21, Issue:10 Topics: Adult; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus; Evaluation Studies as Topic; Humans; Insulin; Mortality; Outpatient Clinics, Hospital; Patients; Phenformin; Prognosis; Statistics as Topic; Time Factors; Tolbutamide	1972
Tolbutamide. Therapeutic trials and clinical practice. California medicine, 1972, Volume: 117, Issue:6 Topics: Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Complications; Evaluation Studies as Topic; Humans; Hypoglycemia; Insulin; Phenformin; Placebos; Tolbutamide	1972
Phenformin and vascular complications of diabetes. The Medical letter on drugs and therapeutics, 1972, Jan-07, Volume: 14, Issue:1 Topics: Clinical Trials as Topic; Diabetic Angiopathies; Humans; Insulin; Phenformin; Placebos; Tolbutamide	1972
The influence of diagnostic criteria on the mortality findings in the University Group Diabetic Programme study of diabetic therapy. The Medical journal of Australia, 1973, Mar-24, Volume: 1, Issue:12 Topics: Blood Glucose; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Mellitus; Diet, Diabetic; Glucose Tolerance Test; Humans; Phenformin; Placebos; Statistics as Topic; Tolbutamide	1973
[Oral therapy in diabetes]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1973, Aug-20, Volume: 93, Issue:23 Topics: Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus; Humans; Phenformin; Placebos; Tolbutamide	1973
Comments on the UGDP study. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1974, Volume: Suppl 4 Topics: Blood Glucose; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Mellitus; Humans; Hypoglycemia; Insulin; Phenformin; Tolbutamide	1974
The UGDP--tolbutamide and mortality. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1974, Volume: Suppl 4 Topics: Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus; Diabetic Angiopathies; Humans; Hyperglycemia; Insulin; Phenformin; Tolbutamide	1974
Oral substitutes for insulin: modern appraisal of their action and indications. Israel journal of medical sciences, 1972, Volume: 8, Issue:6 Topics: Adolescent; Adult; Aged; Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diet, Diabetic; Dogs; Glucose Tolerance Test; Glyburide; Humans; Hypoglycemic Agents; Insulin; Middle Aged; Phenformin; Placebos; Rats; Sulfonamides; Tolbutamide	1972
[Should the prescription of oral antidiabetic drugs be more limited? Results from controlled clinical trials]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1973, Aug-20, Volume: 93, Issue:23 Topics: Aged; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus; Diet, Diabetic; Drug Evaluation; Humans; Phenformin; Placebos; Tolbutamide	1973
Preliminary trial of a powerful new sulphonylurea in maturity-onset diabetes--HB419 (glibenclamide). South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1969, Aug-09, Volume: 43, Issue:32 Topics: Adult; Age Factors; Aged; Blood Chemical Analysis; Chlorpropamide; Clinical Trials as Topic; Diabetes Mellitus; Female; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Phenformin; Sulfonamides; Tolbutamide	1969
HB419 (glibenclamide) in the treatment of diabetes mellitus. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1969, Aug-09, Volume: 43, Issue:32 Topics: Adult; Age Factors; Aged; Biguanides; Chlorpropamide; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus; Female; Gallbladder Diseases; Gastrointestinal Diseases; Humans; Hypoglycemic Agents; Kidney Diseases; Liver Diseases; Male; Metformin; Middle Aged; Phenformin; Sulfonamides; Tolbutamide; Urea; Vascular Diseases	1969
Effects of hypoglycemic agents on vascular complications in patients with adult-onset diabetes. IV. A preliminary report on phenoformin results. JAMA, 1971, Aug-09, Volume: 217, Issue:6 Topics: Age Factors; Aged; Blood Glucose; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Diet, Diabetic; Evaluation Studies as Topic; Female; Follow-Up Studies; Humans; Insulin; Male; Middle Aged; Phenformin; Placebos; Prospective Studies; Time Factors; Tolbutamide; Vascular Diseases	1971
The UGDP study. JAMA, 1971, Dec-13, Volume: 218, Issue:11 Topics: Aged; Blood Glucose; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Mellitus; Diabetic Angiopathies; Humans; Hypoglycemic Agents; Insulin; Phenformin; Placebos; Tolbutamide	1971
A prospective view of the treatment of adult-onset diabetes with special reference to the University Group Diabetes Program and oral hypoglycemic agents. The Medical clinics of North America, 1971, Volume: 55, Issue:4 Topics: Angina Pectoris; Blood Glucose; Clinical Trials as Topic; Creatinine; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Diet, Diabetic; Female; Fundus Oculi; Glycosuria; Humans; Hypertension; Hypoglycemic Agents; Insulin; Male; Middle Aged; Phenformin; Physical Examination; Placebos; Prospective Studies; Proteinuria; Tolbutamide; Visual Acuity	1971
Influence of hypoglycemic agents on blood lipids and body weight in ketoacidosis-resistant diabetics. Annals of the New York Academy of Sciences, 1968, Mar-26, Volume: 148, Issue:3 Topics: Adult; Aged; Body Weight; Cholesterol; Clinical Trials as Topic; Diabetes Mellitus; Diabetic Ketoacidosis; Fatty Acids, Nonesterified; Female; Humans; Lipids; Male; Middle Aged; Phenformin; Tolbutamide; Triglycerides	1968
The relationship of treatment to weight in a randomized study of maturity-onset diabetes. Annals of the New York Academy of Sciences, 1968, Mar-26, Volume: 148, Issue:3 Topics: Analysis of Variance; Body Weight; Diabetes Mellitus; Follow-Up Studies; Humans; Insulin, Long-Acting; Middle Aged; Phenformin; Placebos; Tolbutamide	1968
Effect of sulfonylurea drugs on plasma free fatty acid and blood glucose concentrations in man. Diabetes, 1966, Volume: 15, Issue:5 Topics: Acetohexamide; Adipose Tissue; Animals; Blood Glucose; Diabetes Mellitus; Fasting; Fatty Acids; Glycerol; Humans; In Vitro Techniques; Lipid Metabolism; Phenformin; Placebos; Rats; Sulfadiazine; Tolbutamide	1966
Effects of hypoglycemic agents on vascular complications in patients with adult-onset diabetes. VIII. Evaluation of insulin therapy: final report. Diabetes, 1982, Volume: 31 Suppl 5 Topics: Adult; Aged; Blood Glucose; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Mellitus; Diabetic Angiopathies; Diet, Diabetic; Double-Blind Method; Female; Glucose Tolerance Test; Hemodynamics; Humans; Insulin; Longitudinal Studies; Male; Middle Aged; Mortality; Patient Compliance; Phenformin; Prospective Studies; Research Design; Statistics as Topic; Tolbutamide	1982
The crux of the UGDP. Spurious results and biologically inappropriate data analysis. Diabetologia, 1980, Volume: 18, Issue:3 Topics: Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Mellitus; Diet, Diabetic; Female; Follow-Up Studies; Humans; Insulin; Male; Patient Compliance; Patient Dropouts; Phenformin; Placebos; Sex Factors; Tolbutamide	1980
Therapy of type 2 diabetes, cardiovascular death, and the UGDP. American heart journal, 1999, Volume: 138, Issue:5 Pt 1 Topics: Angioplasty, Balloon, Coronary; Blood Glucose; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Phenformin; Prospective Studies; Risk Factors; Survival Rate; Tolbutamide; Treatment Outcome; Universities	1999

Other Studies

154 other study(ies) available for tolbutamide and phenformin

Article	Year
Sulfonyliminoimidazolidines. A new class of oral hypoglycemic agents. 2. Mode of action and X-ray structure of 1-[[p-[2-(crotonylamino)ethyl]phenyl]sulfonyl]-3-cyclohexyl-2-iminoimidazolidine. Journal of medicinal chemistry, 1983, Volume: 26, Issue:7 Topics: Animals; Biological Assay; Hypoglycemic Agents; Imidazoles; Imidazolidines; Insulin; Insulin Secretion; Islets of Langerhans; Molecular Conformation; Rabbits; Structure-Activity Relationship; X-Ray Diffraction	1983
Sulfonyliminoimidazolidines. A new class of oral hypoglycemic agents. 1. 1-[[p-[2-(acylamino)ethyl]phenyl]sulfonyl]-2-iminoimidazolidines. Journal of medicinal chemistry, 1983, Volume: 26, Issue:7 Topics: Animals; Biological Assay; Blood Glucose; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Imidazoles; Indicators and Reagents; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Sulfones	1983
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
[Objectionable conservatism or sensible policy in pharmacotherapy?]. Nederlands tijdschrift voor geneeskunde, 1976, Jan-03, Volume: 120, Issue:1 Topics: Central Nervous System Stimulants; Child; Clioquinol; Diethylstilbestrol; Drug-Related Side Effects and Adverse Reactions; Humans; Male; Oxyphenisatin Acetate; Phenformin; Practolol; Reserpine; Tolbutamide	1976
Oral hypoglycaemics in diabetes mellitus. Lancet (London, England), 1975, Sep-13, Volume: 2, Issue:7933 Topics: Administration, Oral; Cardiovascular Diseases; Diabetes Mellitus; Humans; Hypoglycemic Agents; Middle Aged; Phenformin; Placebos; Tolbutamide	1975
The oral hypoglycemic controversy. Stay as sweet as you are. Legal aspects of medical practice, 1979, Volume: 7, Issue:3 Topics: Cardiovascular Diseases; Diabetes Mellitus; Diabetic Ketoacidosis; Drug Evaluation; Humans; Hypoglycemic Agents; Insulin; Jurisprudence; Lactates; Phenformin; Placebos; Research Design; Tolbutamide; United States; United States Food and Drug Administration	1979
Side effects of therapy in diabetes evaluated by a self-administered questionnaire. Journal of chronic diseases, 1977, Volume: 30, Issue:1 Topics: Chlorpropamide; Diabetes Mellitus; Diet, Diabetic; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Patient Acceptance of Health Care; Phenformin; Surveys and Questionnaires; Tolbutamide	1977
[Clinico-statistical studies of the use of oral hypoglycemic agents in the therapy of diabetes: critical evaluation of their effectiveness and tolerance]. La Clinica terapeutica, 1977, Jul-15, Volume: 82, Issue:1 Topics: Adult; Aged; Chlorpropamide; Diabetes Mellitus; Drug Evaluation; Drug Therapy, Combination; Female; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Phenformin; Tolbutamide	1977
[Diurnal changes in the blood level of lactates and pyruvates in diabetes mellitus depending on the type of treatment]. Polskie Archiwum Medycyny Wewnetrznej, 1979, Volume: 61, Issue:4 Topics: Adult; Aged; Diabetes Mellitus; Female; Humans; Insulin; Lactates; Male; Middle Aged; Phenformin; Pyruvates; Tolbutamide	1979
Reduction of the severity of nephropathy in aging Fischer 344 rats treated with analogs of arylsulfonyluria. Toxicology and applied pharmacology, 1979, Volume: 49, Issue:3 Topics: Acetohexamide; Animals; Chlorpropamide; Female; Hypoglycemic Agents; Kidney Diseases; Male; Phenformin; Rats; Rats, Inbred F344; Sulfonylurea Compounds; Tolazamide; Tolbutamide	1979
Effect of insulin, tolbutamide & phenformin on tissue glycoproteins in rabbits. Indian journal of biochemistry & biophysics, 1977, Volume: 14, Issue:2 Topics: Animals; Fucose; Glycoproteins; Hexosamines; Hexoses; Insulin; Male; Phenformin; Rabbits; Sialic Acids; Tolbutamide	1977
Determination of oral anti-diabetic agents in human body fluids using high-performance liquid chromatography. Journal of chromatography, 1978, Feb-11, Volume: 149 Topics: Administration, Oral; Chromatography, High Pressure Liquid; Humans; Phenformin; Tolbutamide	1978
Effect of administration of insulin, tolbutamide & phenformin on tissue glycoproteins in alloxan diabetic rabbits. Indian journal of biochemistry & biophysics, 1978, Volume: 15, Issue:2 Topics: Animals; Aorta; Cartilage; Diabetes Mellitus, Experimental; Glycoproteins; Insulin; Male; Phenformin; Rabbits; Skin; Tissue Distribution; Tolbutamide	1978
Stability of lysosomes in tissues of alloxan diabetic rabbits & effect of administration of insulin, tolbutamide & phenformin. Indian journal of biochemistry & biophysics, 1978, Volume: 15, Issue:4 Topics: Animals; Diabetes Mellitus, Experimental; Glucuronidase; Insulin; Lysosomes; Male; Phenformin; Rabbits; Tissue Distribution; Tolbutamide	1978
Myocardial infarction in diabetics. The Quarterly journal of medicine, 1975, Volume: 44, Issue:173 Topics: Administration, Oral; Adult; Aged; Chlorpropamide; Coronary Care Units; Diabetes Complications; Diabetes Mellitus; Diabetic Retinopathy; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Myocardial Infarction; Phenformin; Sex Factors; Sulfonylurea Compounds; Tolbutamide	1975
The effect of chronic oral antidiabetic therapy on insulin and glucagon responses to a meal. Diabetes, 1977, Volume: 26, Issue:4 Topics: Acetohexamide; Administration, Oral; Adult; Aged; Chlorpropamide; Diabetes Mellitus; Female; Glucagon; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Phenformin; Time Factors; Tolazamide; Tolbutamide	1977
Effect of insulin, tolbutamide and phenformin on the serum glycoprotein concentration in normal rabbits. Indian journal of experimental biology, 1976, Volume: 14, Issue:2 Topics: Animals; Glycoproteins; Insulin, Long-Acting; Male; Phenformin; Rabbits; Tolbutamide	1976
Oral hypoglycaemic agents--dangers and contraindications. The Medical journal of Australia, 1976, Oct-16, Volume: 2, Issue:16 Topics: Aged; Biguanides; Cardiovascular Diseases; Diabetes Mellitus; Female; Humans; Hypoglycemic Agents; Lactates; Phenformin; Pregnancy; Sulfonylurea Compounds; Tolbutamide	1976
Editorial: Oral hypoglycemic drugs. Journal of the Tennessee Medical Association, 1975, Volume: 68, Issue:4 Topics: Cardiovascular Diseases; Diabetes Mellitus; Diet, Diabetic; Humans; Insulin; Phenformin; Tolbutamide	1975
Farewell to phenformin for treating diabetes mellitus. Annals of internal medicine, 1975, Volume: 83, Issue:4 Topics: Cardiovascular Diseases; Diabetes Mellitus; Humans; Insulin; Phenformin; Tolbutamide	1975
Editorial: Let's stop the Donnybrook. A perspective on the UGDP-Biometric Society Study. JAMA, 1975, Mar-24, Volume: 231, Issue:12 Topics: Administration, Oral; Adult; Aged; American Medical Association; Biometry; Cardiovascular Diseases; Diabetes Mellitus; Female; Humans; Hypoglycemic Agents; Male; National Institutes of Health (U.S.); Periodicals as Topic; Phenformin; Publishing; Tolbutamide; United States; United States Food and Drug Administration	1975
Effect of calcium chloride on some metabolic actions of certain antidiabetic drugs in normal and alloxanised rabbits. Die Pharmazie, 1975, Volume: 30, Issue:9 Topics: Animals; Calcium Chloride; Diabetes Mellitus, Experimental; Drug Antagonism; Drug Synergism; Insulin; Insulysin; Liver; Male; Pancreas; Phenformin; Rabbits; Tolbutamide; Zinc	1975
The management of pregnancy in diabetes mellitus. The Practitioner, 1975, Volume: 215, Issue:1289 Topics: Birth Weight; Blood Glucose; Chlorpropamide; Delivery, Obstetric; Diet, Diabetic; Female; Fetal Death; Humans; Infant, Newborn; Insulin; Ketosis; Maternal Age; Metformin; Phenformin; Pregnancy; Pregnancy in Diabetics; Time Factors; Tolbutamide	1975
[Letter: Oral antidiabetics and cardiovascular disorders]. Nederlands tijdschrift voor geneeskunde, 1975, Nov-01, Volume: 119, Issue:44 Topics: Cardiovascular Diseases; Female; Humans; Hypoglycemic Agents; Middle Aged; Phenformin; Tolbutamide	1975
[Letter: Heart death and oral antidiabetics]. Nederlands tijdschrift voor geneeskunde, 1975, Nov-01, Volume: 119, Issue:44 Topics: Cardiovascular Diseases; Female; Humans; Hypoglycemic Agents; Phenformin; Tolbutamide	1975
The tolbutamide controversy. Comprehensive therapy, 1975, Volume: 1, Issue:1 Topics: Cardiovascular Diseases; Diabetes Mellitus; Humans; Phenformin; Tolbutamide; United States	1975
The oral antidiabetic agents. American family physician, 1976, Volume: 13, Issue:1 Topics: Administration, Oral; Adult; Blood Glucose; Body Weight; Cardiovascular Diseases; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diet, Diabetic; Drug Interactions; Humans; Hypoglycemia; Hypoglycemic Agents; Phenformin; Tolbutamide; Triglycerides	1976
The interaction of oral hypoglycaemic drugs with insulin on steroid metabolism in hepatocytes isolated from control and diabetic male rats. Biochemical pharmacology, 1990, Nov-15, Volume: 40, Issue:10 Topics: Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Interactions; Insulin; Liver; Male; Phenformin; Rats; Steroids; Tolbutamide	1990
[Effect of antidiabetics on post-exercise alaninemia in patients with non-insulin-dependent diabetes mellitus (type 2)]. Polskie Archiwum Medycyny Wewnetrznej, 1989, Volume: 81, Issue:4 Topics: Adult; Alanine; Diabetes Mellitus, Type 2; Drug Interactions; Drug Therapy, Combination; Exercise; Exercise Test; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Phenformin; Tolbutamide	1989
Electron microscopic quantification of diabetic microangiopathy. Diabetes, 1973, Volume: 22, Issue:7 Topics: Adolescent; Adult; Aged; Basement Membrane; Capillaries; Diabetes Mellitus; Diabetic Angiopathies; Evaluation Studies as Topic; Female; Glutaral; Humans; Insulin; Male; Methods; Microcirculation; Microscopy, Electron; Middle Aged; Muscles; Osmium; Phenformin; Staining and Labeling; Tolbutamide	1973
Regulation by various hormones and agents of adenosine-3',5'-monophosphate levels in islets of Langerhans of rats. Biochemical pharmacology, 1974, May-01, Volume: 23, Issue:9 Topics: Adenine; Adrenergic beta-Antagonists; Adrenocorticotropic Hormone; Animals; Cresols; Cyclic AMP; Epinephrine; Glucagon; Glucose; Guanosine Triphosphate; Hormones; In Vitro Techniques; Islets of Langerhans; Isoproterenol; Leucine; Phenformin; Phenoxybenzamine; Phentolamine; Propanolamines; Propranolol; Propylamines; Prostaglandins; Rats; Receptors, Adrenergic; Secretin; Sotalol; Theophylline; Thyrotropin; Tolbutamide; Tritium	1974
Plasma-insulin in mild juvenile diabetes. Lancet (London, England), 1967, Jun-10, Volume: 1, Issue:7502 Topics: Adult; Diabetes Mellitus, Type 1; Female; Glucose Tolerance Test; Humans; Immunoassay; Insulin; Insulin Resistance; Male; Phenformin; Tolbutamide	1967
Oral hypoglycemic therapy and associated hypothyroidism. Annals of the New York Academy of Sciences, 1968, Mar-26, Volume: 148, Issue:3 Topics: Acetohexamide; Aged; Diabetes Mellitus; Female; Humans; Hypoglycemic Agents; Hypothyroidism; Iatrogenic Disease; Ion Exchange Resins; Male; Middle Aged; Phenformin; Thyroid Function Tests; Thyroid Gland; Tolazamide; Tolbutamide; Triiodothyronine	1968
[Hypoglycemia caused by oral antidiabetic agents]. Nederlands tijdschrift voor geneeskunde, 1973, Jul-07, Volume: 117, Issue:27 Topics: Adult; Aged; Chlorpropamide; Delayed-Action Preparations; Diet; Female; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Kidney Diseases; Liver Diseases; Male; Middle Aged; Phenformin; Tolazamide; Tolbutamide	1973
Homeostasis of body weight in a diabetes clinic population. Diabetes, 1974, Volume: 23, Issue:4 Topics: Acetohexamide; Adolescent; Adult; Age Factors; Aged; Appetite Regulation; Blood Glucose; Body Weight; Child; Chlorpropamide; Diabetes Mellitus; Diabetic Ketoacidosis; Diet Therapy; Feeding Behavior; Female; Homeostasis; Humans; Insulin; Male; Middle Aged; Phenformin; Regression Analysis; Time Factors; Tolbutamide	1974
Editorial: Oral therapy in diabetes mellitus. Southern medical journal, 1974, Volume: 67, Issue:6 Topics: Acetohexamide; Biguanides; Chlorpropamide; Diabetes Mellitus; Diabetic Ketoacidosis; Diet Therapy; Humans; Hypoglycemia; Hypoglycemic Agents; Lactates; Phenformin; Placebos; Pyruvates; Sulfonylurea Compounds; Tolazamide; Tolbutamide; Typhoid Fever	1974
[The glibenclamide-phenformin combination in the therapy of diabetes mellitus]. Minerva medica, 1974, Aug-29, Volume: 65, Issue:59 Topics: Adult; Aged; Biguanides; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Drug Combinations; Drug Evaluation; Drug Synergism; Female; Glyburide; Humans; Insulin; Male; Middle Aged; Phenformin; Tolbutamide	1974
[Oral antidiabetic therapy with delayed-action glibenclamide and phenformin in fixed combination]. Minerva medica, 1974, Sep-01, Volume: 65, Issue:60 Topics: Adult; Aged; Blood Glucose; Carbutamide; Cholesterol; Delayed-Action Preparations; Diabetes Mellitus; Drug Combinations; Evaluation Studies as Topic; Fatty Acids, Nonesterified; Female; Glyburide; Glycosuria; Humans; Lipids; Male; Metformin; Middle Aged; Phenformin; Tolbutamide; Triglycerides	1974
Effect of insulin and some oral hypoglycaemic agents on in vitro synthesis of glucosamine by rat liver. Indian journal of biochemistry, 1969, Volume: 6, Issue:4 Topics: Animals; Glucosamine; Glutamine; Hexosephosphates; Insulin; Liver; Phenformin; Rats; Tolbutamide; Transaminases	1969
Effect of long term administration of tolbutamide and phenformin on the aortic glycosaminoglycans in normal rats. Indian journal of biochemistry & biophysics, 1973, Volume: 10, Issue:1 Topics: Animals; Aorta; Cholesterol; Glycosaminoglycans; Male; Phenformin; Phospholipids; Rats; Tolbutamide; Triglycerides	1973
Site of the in vitro inhibition of cholesterol biosynthesis by tolbutamide and phenethylbiguanide. Biochemistry, 1965, Volume: 4, Issue:6 Topics: Animals; Anticholesteremic Agents; Cholesterol; Chromatography, Paper; Diphosphates; In Vitro Techniques; Liver; Mevalonic Acid; Phenformin; Rats; Squalene; Sterols; Subcellular Fractions; Tolbutamide	1965
The mechanism of action antilipolytic agents: a comparison of the effects of PGE1, insulin, tolbutamide, and phenformin on lipolysis induced by dibutryl cyclic AMP. Diabetes, 1968, Volume: 17 Topics: Adenine Nucleotides; Adipose Tissue; Animals; Cyclic AMP; In Vitro Techniques; Insulin; Lipase; Lipid Metabolism; Phenformin; Phosphoric Monoester Hydrolases; Prostaglandins; Rats; Theophylline; Tolbutamide	1968
Mechanism of action of antilipolytic agents: comparison of the effects of insulin, tolbutamide, and phenformin on lipolysis induced by dibutyryl cyclic AMP plus theophylline. Metabolism: clinical and experimental, 1969, Volume: 18, Issue:11 Topics: Adenine Nucleotides; Adipose Tissue; Animals; Cyclic AMP; Epididymis; In Vitro Techniques; Insulin; Lipid Metabolism; Male; Phenformin; Rats; Theophylline; Tolbutamide	1969
Mode of action of oral hypoglycaemic agents. II. Sulphonylureas & biguanides in rats. Indian journal of biochemistry, 1969, Volume: 6, Issue:1 Topics: Acetohexamide; Administration, Oral; Adrenocorticotropic Hormone; Animals; Carbohydrate Metabolism; Chlorpropamide; Depression, Chemical; Enzyme Inhibitors; Epinephrine; Glucose; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Hypoglycemic Agents; In Vitro Techniques; Insulin; Isomerases; Lipoprotein Lipase; Metabolism; Muscles; Phenformin; Phosphorylases; Rats; Stimulation, Chemical; Sulfonylurea Compounds; Tolbutamide; Trioses	1969
The effect of sulfonylurea drugs on rabbit myocardial contractility, canine purkinje fiber automaticity, and adenyl cyclase activity from rabbit and human hearts. The Journal of clinical investigation, 1972, Volume: 51, Issue:9 Topics: Acetohexamide; Adenylyl Cyclases; Animals; Chlorpropamide; Culture Techniques; Cyclic AMP; Dogs; Heart; Heart Atria; Heart Conduction System; Humans; Membrane Potentials; Microelectrodes; Myocardium; Phenformin; Propranolol; Rabbits; Stimulation, Chemical; Sulfonylurea Compounds; Theophylline; Tolazamide; Tolbutamide	1972
Studies on the effect of oral hypoglycaemic agents on hepatic glycogenolysis. Pharmacological research communications, 1974, Volume: 6, Issue:6 Topics: Acetohexamide; Animals; Blood Glucose; Depression, Chemical; Diabetes Mellitus, Experimental; Glucose-6-Phosphatase; Hypoglycemic Agents; In Vitro Techniques; Liver; Liver Glycogen; Male; Metformin; Phenformin; Phosphorylases; Rats; Sulfonamides; Tolbutamide	1974
Inhibition of lipid biosynthesis. Annals of the New York Academy of Sciences, 1968, Mar-26, Volume: 148, Issue:3 Topics: Acetates; Animals; Anticholesteremic Agents; Antimetabolites; Chlorpropamide; Cholestanes; Cholesterol; Chromatography; Depression, Chemical; Hydroxysteroid Dehydrogenases; Hypolipidemic Agents; Lipids; Liver; Mevalonic Acid; NADP; Phenformin; Rats; Squalene; Sterols; Tolbutamide; Tritium	1968
Letter: Tolbutamide revisited. JAMA, 1974, Jun-17, Volume: 228, Issue:12 Topics: Animals; Arrhythmias, Cardiac; Cardiovascular Diseases; Heart; Humans; Hypoglycemic Agents; Phenformin; Purkinje Cells; Tolbutamide	1974
Drug-induced malabsorption of vitamin B12. VI. Malabsorption of vitamin B12 during treatment with phenformin. Acta medica Scandinavica, 1974, Volume: 196, Issue:4 Topics: Aged; Chlorpropamide; Cobalt Radioisotopes; Diabetes Mellitus; Humans; Middle Aged; Phenformin; Schilling Test; Tolbutamide; Vitamin B 12; Vitamin B 12 Deficiency; Xylose	1974
[Infantile diabetes and treatment with oral hypoglycemizing agents (function tests of the endocrine pancreatic before and after one year of therapy)]. Minerva pediatrica, 1972, Jun-02, Volume: 24, Issue:20 Topics: Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Glucose Tolerance Test; Glyburide; Humans; Insulin; Male; Pancreas; Phenformin; Sulfonylurea Compounds; Tolbutamide	1972
Oral therapy in diabetes. Journal of the Royal College of Physicians of London, 1972, Volume: 7, Issue:1 Topics: Acetohexamide; Administration, Oral; Animals; Chlorpropamide; Diabetes Mellitus; Diet Therapy; Evaluation Studies as Topic; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Obesity; Phenformin; Pyrimidines; Sulfonamides; Time Factors; Tolbutamide	1972
Hypothermia in diabetic acidosis. Hormones, 1972, Volume: 3, Issue:1 Topics: Acetone; Diabetes Complications; Diabetes Mellitus; Diabetic Ketoacidosis; Female; Glycosuria; Humans; Hypothermia; Insulin; Male; Middle Aged; Phenformin; Proteinuria; Tolbutamide	1972
Effect of blood sugar control on the accumulation of sorbitol and fructose in nervous tissues. Diabetes, 1972, Volume: 21, Issue:12 Topics: Animals; Blood Glucose; Fructose; Insulin; Male; Phenformin; Rats; Sciatic Nerve; Sorbitol; Spinal Cord; Time Factors; Tolbutamide	1972
Metabolism of glycosaminoglycans in alloxan diabetic rats--hepatic UDPG pyrophosphorylase activity. Indian journal of biochemistry & biophysics, 1972, Volume: 9, Issue:2 Topics: Alcohol Oxidoreductases; Animals; Diabetes Mellitus, Experimental; Enzyme Activation; In Vitro Techniques; Insulin; Liver; Male; Nucleotidyltransferases; Phenformin; Rats; Stimulation, Chemical; Tolbutamide	1972
Long-term results with oral hypoglycemic drugs. Journal of the American Geriatrics Society, 1973, Volume: 21, Issue:2 Topics: Acetohexamide; Adult; Aged; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Diet, Diabetic; Humans; Longevity; Middle Aged; Phenformin; Sulfonylurea Compounds; Tolazamide; Tolbutamide	1973
Oral hypoglycaemic agents. The Medical journal of Australia, 1973, Mar-24, Volume: 1, Issue:12 Topics: Cardiovascular Diseases; Diabetes Mellitus; Humans; Hypoglycemic Agents; Male; Phenformin; Tolbutamide	1973
Alimentary hypoglycemia in the absence of gastrointestinal surgery. The New England journal of medicine, 1973, Jun-07, Volume: 288, Issue:23 Topics: Adult; Blood Glucose; Diabetes Mellitus; Diagnosis, Differential; Eating; Fasting; Female; Gastrointestinal Motility; Glucose; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemia; Insulin; Insulin Secretion; Male; Middle Aged; Phenformin; Prediabetic State; Radionuclide Imaging; Stomach; Tolbutamide	1973
Therapy of early diabetes. The University Group Diabetes Program. Advances in metabolic disorders, 1973, Volume: 2 Topics: Blood Glucose; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus; Diet Therapy; Evaluation Studies as Topic; Female; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Phenformin; Sulfonylurea Compounds; Tolbutamide	1973
Progress report on the prophylactic use of oral hypoglycemic drugs in asymptomatic diabetes: neurovascular studies. Advances in metabolic disorders, 1973, Volume: 2 Topics: Adult; Angina Pectoris; Arteries; Blood Glucose; Cardiovascular Diseases; Cerebrovascular Disorders; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Neuropathies; Evaluation Studies as Topic; Fatty Acids, Nonesterified; Female; Glucose Tolerance Test; Humans; Insulin; Male; Middle Aged; Myocardial Infarction; Neural Conduction; Peripheral Nerves; Phenformin; Pulse; Tolbutamide	1973
Effects of long-term feeding of tolbutamide and phenformin on normal rats. The Indian journal of medical research, 1973, Volume: 61, Issue:7 Topics: Amino Acids; Animals; Blood Glucose; Blood Proteins; Lipids; Liver; Liver Glycogen; Male; Phenformin; Proteins; Rats; Tolbutamide	1973
Controversy over drug therapy of adult-onset diabetes mellitus. Texas medicine, 1973, Volume: 69, Issue:12 Topics: Adult; Diabetes Mellitus; Humans; Phenformin; Tolbutamide	1973
Effect of long term administration of tolbutamide and phenformin to normal rats on the metabolism of glycosaminoglycans: UDPG dehydrogenase activity of the liver. Indian journal of biochemistry & biophysics, 1973, Volume: 10, Issue:1 Topics: Alcohol Oxidoreductases; Animals; Aorta; Depression, Chemical; Liver; Male; Phenformin; Rats; Tolbutamide; Uridine Diphosphate Sugars; Uronic Acids	1973
Effect of long-term administration of tolbuamide & phenformin to normal rats on the metabolism of glycosaminoglycans L-glutamine: D-fructose-6-phosphate aminotransferase activity of the liver & aorta. Indian journal of biochemistry & biophysics, 1973, Volume: 10, Issue:2 Topics: Animals; Aorta; Depression, Chemical; Fructosephosphates; Glutamine; Hexosamines; Liver; Male; Phenformin; Rats; Time Factors; Tolbutamide; Transaminases	1973
Clinical experiences in oral antidiabetic therapy with sulphonylureas and biguanides. Australian and New Zealand journal of medicine, 1971, Volume: 1 Topics: Aged; Biguanides; Blood Glucose; Diabetes Mellitus; Glyburide; Humans; Insulin; Middle Aged; Phenformin; Sulfonylurea Compounds; Tolbutamide	1971
[The venture of University Group Diabetes Program (UGDP). Some personal reflexions. Tolbutamide and phenformin under accusation]. La Nouvelle presse medicale, 1972, Jan-29, Volume: 1, Issue:5 Topics: Diabetes Complications; Diabetes Mellitus; Humans; Phenformin; Tolbutamide; United States	1972
Assessment of the need for continued oral therapy in diabetics. British medical journal, 1972, Mar-11, Volume: 1, Issue:5801 Topics: Administration, Oral; Adult; Aged; Blood Glucose; Body Weight; Chlorpropamide; Diabetes Mellitus; Female; Humans; Hypoglycemic Agents; Male; Middle Aged; Obesity; Phenformin; Placebos; Recurrence; Sulfonylurea Compounds; Tolbutamide	1972
Characterization of a rat liver protease with specificity for insulin. Endocrinology, 1972, Volume: 91, Issue:3 Topics: Animals; Chromatography, Gel; Chromatography, Ion Exchange; Ethylmaleimide; Glutathione; Growth Hormone; Humans; Hydrogen-Ion Concentration; Hydroxymercuribenzoates; Insulin; Liver; Male; Mercaptoethanol; Microsomes, Liver; Mitochondria; Molecular Weight; Peptide Hydrolases; Phenformin; Proinsulin; Protease Inhibitors; Rats; Swine; Tolbutamide; Ultracentrifugation	1972
The direct effect of oral hypoglycaemic agents on glucose metabolism by adipose tissue. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1972, Volume: 4, Issue:3 Topics: Adipose Tissue; Animals; Biological Transport; Carbon Dioxide; Carbon Isotopes; Chlorpropamide; Depression, Chemical; Epididymis; Glucose; In Vitro Techniques; Insulin; Lipids; Male; Phenformin; Rats; Stimulation, Chemical; Tolbutamide	1972
A summary of criticisms of the findings and conclusions of the University Group Diabetes Program (UGDP). Diabetes, 1972, Volume: 21, Issue:9 Topics: Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus; Diet, Diabetic; Evaluation Studies as Topic; Humans; Insulin; Phenformin; Schools, Medical; Tolbutamide; United States	1972
Management of adult-onset diabetes. The impact of the University Group Diabetes Program. Postgraduate medicine, 1972, Volume: 52, Issue:1 Topics: Administration, Oral; Adult; Aged; Attitude of Health Personnel; Cardiovascular Diseases; Diabetes Mellitus; Diet Therapy; Ethics, Medical; Female; Health Surveys; Humans; Hypoglycemic Agents; Insulin; Male; Phenformin; Sulfonylurea Compounds; Tolbutamide; United States; United States Food and Drug Administration	1972
Adverse reactions to oral antidiabetic agents. British medical journal, 1971, Jul-03, Volume: 3, Issue:5765 Topics: Acetohexamide; Acidosis; Administration, Oral; Anemia; Chlorpropamide; Drug Antagonism; Drug Synergism; England; Ethanol; Female; Fetus; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Metformin; Phenformin; Pregnancy; Scotland; Skin Diseases; Skin Manifestations; Tolazamide; Tolbutamide; Wales	1971
[Comparative activity of some biguanides, sulfonylureas and their combinations on blood sugar and lactic acid in the guinea pig. II]. Bollettino chimico farmaceutico, 1971, Volume: 110, Issue:4 Topics: Amantadine; Animals; Biguanides; Blood Glucose; Chlorpropamide; Guinea Pigs; Lactates; Metformin; Phenformin; Sulfonylurea Compounds; Tolbutamide	1971
A study of comparative effectiveness of oral hypoglycaemic agents in single dose in diabetes mellitus. Journal of the Indian Medical Association, 1971, Jun-16, Volume: 56, Issue:12 Topics: Administration, Oral; Adult; Aged; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Female; Glucose Tolerance Test; Glycosuria; Humans; Male; Middle Aged; Phenformin; Time Factors; Tolbutamide	1971
Seminars on diabetes. II. Principles of management. Canadian Medical Association journal, 1971, Volume: 105, Issue:9 Topics: Acetohexamide; Chlorpropamide; Diabetes Mellitus; Diet, Diabetic; Female; Health Education; Humans; Insulin; Male; Patient Care Team; Personality; Phenformin; Pregnancy; Pregnancy in Diabetics; Tolbutamide	1971
A study of some aspects of plasma free insulin-like activity. Indian journal of physiology and pharmacology, 1971, Volume: 15, Issue:2 Topics: Animals; Blood Glucose; Diabetes Mellitus; Female; Glucose; Humans; Hypoglycemic Agents; Labor, Obstetric; Phenformin; Pregnancy; Pregnancy in Diabetics; Rats; Tolbutamide	1971
Tolbutamide mortality in the six "phenformin clinics". JAMA, 1971, Oct-25, Volume: 218, Issue:4 Topics: Diabetes Mellitus; Humans; Phenformin; Tolbutamide	1971
Effects of phenformin on insulin reserve and release. Annals of the New York Academy of Sciences, 1968, Mar-26, Volume: 148, Issue:3 Topics: Diabetes Mellitus; Drug Tolerance; Ethanol; Glucose Tolerance Test; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Insulin Secretion; Obesity; Phenformin; Tolbutamide	1968
Fibrinolytic effect of biguanides. Annals of the New York Academy of Sciences, 1968, Mar-26, Volume: 148, Issue:3 Topics: Adult; Aged; Angina Pectoris; Arteriosclerosis Obliterans; Biguanides; Chlorpropamide; Coronary Disease; Ethylestrenol; Female; Fibrinolysis; Fibrinolytic Agents; Humans; Male; Metformin; Methenolone; Middle Aged; Phenformin; Tolbutamide	1968
Modification of response to the triamcinolone glucose tolerance test by treatment with oral hypoglycemic agents. Diabetes, 1966, Volume: 15, Issue:10 Topics: Abortion, Habitual; Adolescent; Adult; Blood Glucose; Congenital Abnormalities; Female; Fetal Death; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Middle Aged; Obesity; Phenformin; Polyhydramnios; Pregnancy; Pregnancy Complications; Tolbutamide; Triamcinolone	1966
Insulin in bile. The effect of monosaccharides and hypoglycaemic agents. Diabetologia, 1969, Volume: 5, Issue:5 Topics: Alloxan; Animals; Bile; Fructose; Galactose; Glucose; Hypoglycemic Agents; Injections, Intravenous; Insulin; Iodine Isotopes; Monosaccharides; Phenformin; Rabbits; Radioimmunoassay; Stimulation, Chemical; Tolbutamide	1969
Attempts to delay the progression of chemical diabetes. Advances in metabolic disorders, 1970, Volume: 1 Topics: Acetohexamide; Adolescent; Adult; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Fatty Acids, Nonesterified; Female; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Phenformin; Tolbutamide; Triglycerides	1970
The prophylactic use of oral hypoglycemic drugs in asymptomatic diabetes. Advances in metabolic disorders, 1970, Volume: 1 Topics: Adolescent; Adult; Diabetes Mellitus; Female; Glucose; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Male; Middle Aged; Phenformin; Tolbutamide	1970
Uncoupling action of sulfonylureas on brown fat cells. Molecular pharmacology, 1970, Volume: 6, Issue:5 Topics: Adipose Tissue; Adipose Tissue, Brown; Animals; Carbon Dioxide; Carbon Isotopes; Cysteine; Female; Glucose; Hypoglycemic Agents; Insulin; Lactates; Lipids; Oxidation-Reduction; Oxygen Consumption; Phenformin; Rabbits; Rats; Tolbutamide; Triglycerides	1970
[Glybenclamide and its place among sulfanylureas in the treatment of diabetes mellitus]. Revista clinica espanola, 1970, May-31, Volume: 117, Issue:4 Topics: Adolescent; Adult; Aged; Carbutamide; Child; Cyclohexanes; Diabetes Mellitus; Female; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Phenformin; Sulfones; Tolbutamide; Urea	1970
A comparative study on the effects of three oral hypoglycemic agents on amino acid decarboxylation. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1970, Volume: 135, Issue:2 Topics: Amino Acids; Animals; Carbon Dioxide; Carbon Isotopes; Cats; Chlorpropamide; Culture Techniques; Dogs; Hypoglycemic Agents; Liver; Phenformin; Rabbits; Tolbutamide	1970
The effect of some oral hypoglycaemics on the gamma-aminobutyric acid content in the cerebral hemispheres of adult male mice. European journal of pharmacology, 1970, Volume: 13, Issue:1 Topics: Acetohexamide; Aminobutyrates; Animals; Brain; Brain Chemistry; Hypoglycemic Agents; Male; Mice; Phenformin; Time Factors; Tolbutamide	1970
Long term observations with oral hypoglycemic drugs: sulphonylureas, biguanides and their combination. Indian journal of medical sciences, 1970, Volume: 24, Issue:7 Topics: Administration, Oral; Adult; Age Factors; Aged; Biguanides; Carbutamide; Chlorpropamide; Diabetes Mellitus; Diet; Drug Combinations; Female; Follow-Up Studies; Humans; Male; Middle Aged; Phenformin; Sulfonylurea Compounds; Time Factors; Tolbutamide	1970
Insulin, tolbutamide, phenformin and blood sugar of Rana tigrina. Indian journal of physiology and pharmacology, 1970, Volume: 14, Issue:4 Topics: Animals; Anura; Blood Glucose; Glucose; Hyperglycemia; Insulin; Phenformin; Tolbutamide	1970
Partial remission of diabetes mellitus after oral antidiabetic therapy. Postgraduate medicine, 1971, Volume: 49, Issue:3 Topics: Administration, Oral; Adult; Age Factors; Blood Glucose; Body Weight; Diabetes Mellitus; Diet, Diabetic; Humans; Phenformin; Time Factors; Tolbutamide	1971
Effects of various drugs on insulin antibodies. British journal of pharmacology, 1971, Volume: 42, Issue:1 Topics: Animals; Antibodies; Antineoplastic Agents; Bromouracil; Chlorambucil; Chlorpropamide; Complement Fixation Tests; Cyclophosphamide; Dactinomycin; Diaphragm; Diethylstilbestrol; Drug Synergism; Female; Fluorouracil; Gonadal Steroid Hormones; Guinea Pigs; Hydrocortisone; Injections, Intraperitoneal; Injections, Subcutaneous; Insulin Antibodies; Male; Mercaptopurine; Methotrexate; Neutralization Tests; Phenformin; Testosterone; Tolbutamide; Triazines	1971
Effect of in vivo administration of various oral hypoglycemic agents on hepatic protein synthesis. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1968, Volume: 127, Issue:2 Topics: Animals; Carbon Isotopes; Female; Leucine; Liver; Microsomes; Phenformin; Protein Biosynthesis; Rats; Tolbutamide	1968
Combinations of oral hypoglycemic drugs in obese, insulin-resistant diabetics. Geriatrics, 1968, Volume: 23, Issue:9 Topics: Adult; Aged; Blood Glucose; Carbohydrate Metabolism; Chlorpropamide; Diabetes Mellitus; Drug Synergism; Female; Glycosuria; Humans; Insulin; Insulin Antibodies; Insulin Resistance; Insulin, Isophane; Insulin, Long-Acting; Male; Middle Aged; Obesity; Phenformin; Tolbutamide	1968
[Mild diabetes mellitus in children and young adults. Clinical features and endogenous insulin response]. Nordisk medicin, 1968, Aug-15, Volume: 80, Issue:33 Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diet, Diabetic; Female; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Male; Phenformin; Time Factors; Tolbutamide	1968
The inhibition in vitro of hepatic protein biosynthesis by various oral hypoglycemic agents--site of action. Biochemical pharmacology, 1969, Volume: 18, Issue:3 Topics: Animals; Carbon Isotopes; Chlorpropamide; Female; Hypoglycemic Agents; In Vitro Techniques; Leucine; Liver; Lysine; Microsomes; Phenformin; Phenylalanine; Protein Biosynthesis; Rats; RNA, Transfer; Time Factors; Tolbutamide	1969
Oral hypoglycaemic drugs. British medical journal, 1969, Mar-29, Volume: 1, Issue:5647 Topics: Acetohexamide; Animals; Chlorpropamide; Guinea Pigs; Humans; Hypoglycemic Agents; Metformin; Phenformin; Tolbutamide	1969
Single and combined drug therapy of sulfonylurea failure. The Journal of the Florida Medical Association, 1969, Volume: 56, Issue:4 Topics: Acetohexamide; Aged; Chlorpropamide; Diabetes Mellitus; Humans; Hypoglycemic Agents; Middle Aged; Phenformin; Tolbutamide	1969
Studies on factors which increase peripheral glucose uptake in man. Polskie Archiwum Medycyny Wewnetrznej, 1969, Volume: 42, Issue:3 Topics: Diabetes Mellitus; Exercise Therapy; Glucose; Humans; Hypoglycemic Agents; Obesity; Phenformin; Tolbutamide	1969
Variability in blood cholesterol, triglycerides, free fatty acids, glucose and body weight in maturity-onset diabetics. The American journal of the medical sciences, 1969, Volume: 258, Issue:2 Topics: Adult; Aged; Blood Glucose; Body Weight; Cholesterol; Diabetes Mellitus; Diet Therapy; Fatty Acids, Nonesterified; Female; Humans; Male; Middle Aged; Phenformin; Tolbutamide; Triglycerides	1969
Pharmacological fibrinolysis. Bristol medico-chirurgical journal (1963), 1969, Volume: 84, Issue:312 Topics: Aged; Androsterone; Anticholesteremic Agents; Butyrates; Chlorpropamide; Coronary Disease; Ethylestrenol; Female; Fibrinogen; Fibrinolysis; Humans; Intermittent Claudication; Male; Metformin; Middle Aged; Phenformin; Platelet Adhesiveness; Tolbutamide	1969
Role of phenformin (DBI) as an adjuvant in oral antidiabetic therapy. Metabolism: clinical and experimental, 1965, Volume: 14, Issue:11 Topics: Acetohexamide; Chlorpropamide; Diabetes Mellitus; Humans; Phenformin; Tolbutamide	1965
The treatment of diabetes mellitus with oral hypoglycaemic drugs. Current medicine and drugs, 1965, Volume: 5, Issue:10 Topics: Chlorpropamide; Diabetes Mellitus; Humans; Hypoglycemic Agents; Metformin; Phenformin; Tolbutamide	1965
Effect of tolbutamide and phenformin on lipolysis in adipose tissue in vitro. The American journal of physiology, 1966, Volume: 210, Issue:1 Topics: Adipose Tissue; Animals; Fatty Acids; Glycerol; In Vitro Techniques; Phenformin; Rats; Sulfadiazine; Tolbutamide	1966
Complications in the use of oral hypoglycemic agents. Maryland state medical journal, 1966, Volume: 15, Issue:10 Topics: Chlorpropamide; Humans; Phenformin; Tolbutamide	1966
The effect of phenformin hydrochloride on serum cholesterol and triglyceride levels of the stable adult diabetic. Metabolism: clinical and experimental, 1966, Volume: 15, Issue:9 Topics: Adult; Aged; Blood Glucose; Body Weight; Cholesterol; Diabetes Mellitus; Female; Glycerides; Humans; Insulin; Lipids; Male; Middle Aged; Phenformin; Tolbutamide; Triglycerides	1966
Standards of diabetic control. The Medical clinics of North America, 1966, Volume: 50, Issue:5 Topics: Acetohexamide; Adult; Aged; Diabetes Complications; Diabetes Mellitus; Diet, Diabetic; Female; Humans; Hypoglycemic Agents; Insulin; Middle Aged; Obesity; Phenformin; Tolbutamide	1966
Diabetogenic hyperinsulinism: pathogenesis and implications of sulfonylurea-induced hypothyroidism. Journal of the American Geriatrics Society, 1967, Volume: 15, Issue:7 Topics: Adult; Cholesterol; Diabetes Complications; Diet Therapy; Female; Glucose Tolerance Test; Goiter; Gout; Humans; Hyperinsulinism; Hypoglycemic Agents; Hypothyroidism; Phenformin; Thyroid Function Tests; Tolbutamide; Triparanol	1967
Effect of hypoglycemic agents on liver regeneration. Biochemical pharmacology, 1967, Volume: 16, Issue:6 Topics: Acetohexamide; Animals; Body Weight; Carbutamide; Chlorpropamide; Glucagon; Hypoglycemia; Hypoglycemic Agents; Insulin; Liver Regeneration; Male; Necrosis; Phenformin; Rats; Sulfonylurea Compounds; Tolbutamide	1967
Effect of the oral hypoglycemic agent pirogliride (McN-3495) on glycogen levels of normal and diabetic rats. Biochemistry international, 1983, Volume: 7, Issue:1 Topics: Animals; Diabetes Mellitus, Experimental; Fasting; Glycogen; Hypoglycemic Agents; Insulin; Kinetics; Liver; Liver Glycogen; Male; Muscles; Organ Specificity; Phenformin; Pyrrolidines; Rats; Rats, Inbred Strains; Tolbutamide	1983
Polymorphic drug oxidation in humans. Federation proceedings, 1984, May-15, Volume: 43, Issue:8 Topics: Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochromes b5; Debrisoquin; Humans; Mephenytoin; Microsomes, Liver; Oxidation-Reduction; Pharmaceutical Preparations; Phenacetin; Phenformin; Phenytoin; Polymorphism, Genetic; Sparteine; Tolbutamide	1984
Oral glucose tolerance test in normal sympathectomized & streptozotocin induced diabetic rhesus monkeys: effect on plasma immunoreactive insulin, free fatty acids & blood lactate. Indian journal of experimental biology, 1980, Volume: 18, Issue:6 Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Insulin; Lactates; Macaca mulatta; Male; Phenformin; Sympathectomy; Tolbutamide	1980
Effect of oral hypoglycemic drugs on heart norepinephrine (NE) in rats and mice. Research communications in chemical pathology and pharmacology, 1982, Volume: 35, Issue:1 Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Enzyme Induction; Female; Hypoglycemic Agents; Male; Mice; Microsomes; Myocardium; Norepinephrine; Phenformin; Rats; Rats, Inbred Strains; Tolbutamide	1982
Medical watergate? Critics charge a cover-up at HEW of faulty research. Barron's national business and financial weekly, 1978, Oct-23, Volume: 58, Issue:43 Topics: Aged; Diabetes Mellitus; Drug Industry; Humans; Insulin; Middle Aged; Phenformin; Research Design; Tolbutamide; United States; United States Dept. of Health and Human Services; United States Food and Drug Administration	1978
Tolbutamide-phenformin in ketoacidosis-resistant patients. JAMA, 1960, Dec-24, Volume: 174 Topics: Hypoglycemic Agents; Ketosis; Phenformin; Tolbutamide	1960
[The effect of a combination of N 1-Beta-phenylethylbiguanide (DBI, W 32) with insulin and tolbutamide on the metabolism of guinea pigs]. Klinische Wochenschrift, 1961, Oct-15, Volume: 39 Topics: Animals; Guinea Pigs; Hypoglycemic Agents; Insulin; Phenformin; Tolbutamide	1961
[Action of hypoglycemic drugs on the stomach]. La Semana medica, 1963, Mar-28, Volume: 122 Topics: Chlorpropamide; Gastric Acidity Determination; Hypoglycemic Agents; Phenformin; Stomach; Tolbutamide	1963
A fundamental approach to hypoglycemic therapy. Metabolism: clinical and experimental, 1963, Volume: 12 Topics: Chlorpropamide; Hypoglycemic Agents; Insulin; Phenformin; Tolbutamide	1963
Metabolic balance studies of oral compounds in severe diabetes. Diabetes, 1962, Volume: 11(Suppl) Topics: Carbohydrate Metabolism; Carbutamide; Diabetes Mellitus; Glycosuria; Ketones; Nitrogen; Phenformin; Tolbutamide	1962
Oral hypoglycemic agents. Wisconsin medical journal, 1963, Volume: 62 Topics: Chlorpropamide; Humans; Hypoglycemic Agents; Phenformin; Tolbutamide	1963
"Secondary failures" in the treatment of diabetes mellitus with tolbutamide and with phenformin. Diabetes, 1962, Volume: (Suppl) Topics: Diabetes Mellitus; Humans; Phenformin; Tolbutamide	1962
THE TREATMENT OF DIABETES WITH ORAL DRUGS AND DIET. Medical times, 1963, Volume: 91 Topics: Chlorpropamide; Diabetes Mellitus; Diet; Diet, Reducing; Obesity; Phenformin; Phenmetrazine; Tolbutamide	1963
RESISTANCE AND ALLERGY TO INSULIN. Applied therapeutics, 1963, Volume: 5 Topics: Adrenal Cortex Hormones; Diet; Drug Hypersensitivity; Humans; Hypersensitivity; Insulin; Insulin Antibodies; Mechlorethamine; Neutralization Tests; Phenformin; Tolbutamide	1963
METABOLISM OF THE ALLOXAN DIABETIC RAT RETINA. Archives of ophthalmology (Chicago, Ill. : 1960), 1964, Volume: 71 Topics: Adrenalectomy; Alloxan; Animals; Chlorpropamide; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Hypophysectomy; Metabolism; Phenformin; Rats; Research; Retina; Tolbutamide	1964
ORAL TREATMENT OF DIABETES MELLITUS. The Medical journal of Australia, 1963, Nov-09, Volume: 2 Topics: Administration, Oral; Carbutamide; Diabetes Mellitus; Humans; Hypoglycemic Agents; Phenformin; Tolbutamide	1963
[DIABETIC RETINOPATHY AND ITS TREATMENT]. Archivos de oftalmologia de Buenos Aires, 1963, Volume: 38 Topics: Adrenalectomy; Adrenocorticotropic Hormone; Anabolic Agents; Arteriosclerosis; Carbutamide; Chlorpropamide; Diabetic Retinopathy; Humans; Hypophysectomy; Phenformin; Pituitary Irradiation; Steroids; Testosterone Congeners; Tolbutamide	1963
[ORAL DIABETIC DRUGS]. Nordisk medicin, 1964, Feb-20, Volume: 71 Topics: Carbutamide; Chlorpropamide; Diabetes Mellitus; Female; Humans; Metformin; Phenformin; Pregnancy; Pregnancy in Diabetics; Tolbutamide	1964
[THE INFLUENCE OF THE CONSTITUENTS OF THE LYTIC COCKTAIL ON THE ACTION OF HYPOGLYCEMIC AGENTS]. Archives internationales de pharmacodynamie et de therapie, 1963, Dec-01, Volume: 146 Topics: Alcoholic Beverages; Cardiovascular Agents; Chlorpromazine; Ergot Alkaloids; Guinea Pigs; Hypoglycemic Agents; Insulin; Meperidine; Metformin; Oxytocics; Pharmacology; Phenformin; Promethazine; Research; Tolbutamide	1963
ORAL TREATMENT OF DIABETES MELLITUS. JAMA, 1964, Mar-21, Volume: 187 Topics: Administration, Oral; Chlorpropamide; Diabetes Mellitus; Hypoglycemic Agents; Pharmacology; Phenformin; Prognosis; Statistics as Topic; Tolbutamide; Toxicology	1964
LEUCINE-INDUCED HYPOGLYCAEMIA AND ORAL HYPOGLYCAEMIC DRUGS. British medical journal, 1964, Apr-04, Volume: 1, Issue:5387 Topics: Autoradiography; Carbon Isotopes; Chromatography; Diaphragm; Hypoglycemia; Hypoglycemic Agents; Insulin; Leucine; Pharmacology; Phenformin; Proteins; Rats; Research; Tolbutamide	1964
MANAGEMENT OF THE NEW DIABETIC PATIENT. GP, 1964, Volume: 29 Topics: Chlorpropamide; Diabetes Mellitus; Diet, Diabetic; Disease Management; Humans; Insulin; Phenformin; Tolbutamide	1964
COMBINED TRIAL OF ACETOHEXAMIDE AND TWO DIGUANIDE PREPARATIONS. Irish journal of medical science, 1964, Volume: 457 Topics: Acetohexamide; Chlorpropamide; Diabetes Mellitus; Geriatrics; Hypoglycemic Agents; Insulin; Metformin; Pharmacology; Phenformin; Tolbutamide; Toxicology	1964
A REVIEW OF THE HISTORY OF THE TREATMENT OF DIABETES MELLITUS AND THE SEARCH FOR ORAL HYPOGLYCAEMIC AGENTS. Guy's Hospital reports, 1964, Volume: 113 Topics: Carbutamide; Chlorpropamide; Diabetes Mellitus; Guanidine; Guanidines; History; Humans; Hypoglycemic Agents; Metformin; Phenformin; Sulfonylurea Compounds; Tolbutamide	1964
ORAL HYPOGLYCEMIC AGENTS. The American journal of nursing, 1964, Volume: 64 Topics: Chlorpropamide; Diabetes Mellitus; Hypoglycemic Agents; Phenformin; Tolbutamide	1964
TWO YEARS' EXPERIENCE WITH ACETOHEXAMIDE. Metabolism: clinical and experimental, 1964, Volume: 13 Topics: Acetohexamide; Alkaline Phosphatase; Blood Chemical Analysis; Chlorpropamide; Coloring Agents; Geriatrics; Hypoglycemic Agents; Liver Function Tests; Massachusetts; Phenformin; Sulfobromophthalein; Sulfonylurea Compounds; Tolbutamide; Toxicology; Transaminases; Urine	1964
THE PHARMACOLOGICAL ENHANCEMENT OF BLOOD FIBRINOLYTIC ACTIVITY WITH SPECIAL REFERENCE TO PHENFORMIN. Acta cardiologica, 1964, Volume: 19 Topics: Anabolic Agents; Anticoagulants; Arteriosclerosis Obliterans; Chlorpropamide; Coronary Disease; Fibrinolysis; Humans; Phenformin; Steroids; Thrombolytic Therapy; Tolbutamide	1964
[EXPERIENCES WITH PHENFORMIN IN 100 DIABETIC PATIENTS]. Dapim refuiim. Folia medica, 1963, Volume: 22 Topics: Diabetes Mellitus; Humans; Hypoglycemic Agents; Insulin; Phenformin; Tolbutamide	1963
PHARMACOLOGICAL ENCHANCEMENT OF FIBRINOLYTIC ACTIVITY OF BLOOD. Journal of clinical pathology, 1964, Volume: 17 Topics: Adrenal Cortex Hormones; Anabolic Agents; Arteriosclerosis; Chlorpropamide; Coronary Disease; Fibrinolysis; Heart Block; Humans; Nandrolone; Pharmacology; Phenformin; Prednisone; Steroids; Testosterone; Tolbutamide	1964
ORAL HYPOGLYCEMIC DRUGS. Canadian Medical Association journal, 1964, Aug-22, Volume: 91 Topics: Chlorpropamide; Hypoglycemic Agents; Pharmacology; Phenformin; Tolbutamide	1964
ORAL HYPOGLYCEMIC DRUGS: COMPARATIVE EVALUATION OF TOLBUTAMIDE, CHLORPROPAMIDE AND PHENFORMIN. Medical times, 1964, Volume: 92 Topics: Alkaline Phosphatase; Biomedical Research; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diet, Diabetic; Female; Humans; Hypoglycemic Agents; Insulin; Obesity; Phenformin; Pregnancy; Pregnancy in Diabetics; Statistics as Topic; Tolbutamide; Toxicology	1964
USE OF ACETOHEXAMIDE (DYMELOR) IN DIABETIC PATIENTS WITH SECONDARY FAILURES TO ANTIDIABETIC DRUGS. The Journal of the Indiana State Medical Association, 1964, Volume: 57 Topics: Acetohexamide; Chlorpropamide; Diabetes Mellitus; Drug Therapy; Hypoglycemic Agents; Phenformin; Tolbutamide	1964
COMPLICATIONS OF THERAPY WITH ORAL HYPOGLYCEMIC AGENTS. The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society, 1964, Volume: 116 Topics: Acidosis; Chlorpropamide; Diabetes Mellitus; Diabetic Ketoacidosis; Humans; Hypoglycemia; Hypoglycemic Agents; Lactates; Pancreatic Diseases; Phenformin; Tolbutamide; Toxicology	1964
RECENT ADVANCES AND TRENDS IN DRUG THERAPY. IV. ORAL HYPOGLYCAEMIC AGENTS. The Medical journal of Australia, 1964, Nov-21, Volume: 2 Topics: Acetohexamide; Chlorpropamide; Drug Therapy; Hypoglycemic Agents; Phenformin; Tolbutamide; Toxicology	1964
ASSESSMENT OF ORAL THERAPY IN DIABETES MELLITUS. Postgraduate medical journal, 1964, Volume: 40 Topics: Biomedical Research; Chlorpropamide; Diabetes Mellitus; Humans; Phenformin; Tolbutamide	1964
PHENFORMIN, SERUM LIPIDS AND DIABETES MELLITUS. Lancet (London, England), 1965, May-01, Volume: 1, Issue:7392 Topics: Blood Glucose; Cholesterol; Diabetes Mellitus; Drug Therapy; Glycerides; Humans; Insulin; Lipids; Obesity; Pharmacology; Phenformin; Tolbutamide	1965
LIMITATIONS IN THE USE OF ORAL HYPOGLYCEMIC AGENTS IN JUVENILE PATIENTS WITH DIABETES. The Journal of pediatrics, 1965, Volume: 66 Topics: Adolescent; Blood Chemical Analysis; Blood Glucose; Body Weight; Child; Cholesterol; Diabetes Mellitus; Diabetes Mellitus, Type 1; Drug Therapy; Humans; Hypoglycemic Agents; Insulin; Lipids; Phenformin; Phospholipids; Tolbutamide	1965
TWO MINUTES WITH DIABETES. Medical times, 1965, Volume: 93 Topics: Diabetes Mellitus; Drug Therapy; Humans; Phenformin; Tolbutamide	1965
THE ORAL HYPOGLYCEMIC COMPOUNDS. The Medical clinics of North America, 1965, Volume: 49 Topics: Acetohexamide; Chlorpropamide; Diabetes Mellitus; Drug Therapy; Humans; Hypoglycemic Agents; Phenformin; Tolbutamide; Toxicology	1965
SPONTANEOUS DIABETES MELLITUS IN DOGS. Journal of the American Veterinary Medical Association, 1965, May-15, Volume: 146 Topics: Animals; Chlorpropamide; Diabetes Mellitus; Diagnosis; Dog Diseases; Dogs; Drug Therapy; Insulin; Insulin, Isophane; Insulin, Long-Acting; Pathology; Phenformin; Protamines; Tolbutamide	1965
ORAL THERAPY FOR DIABETES MELLITUS. JAMA, 1965, Sep-06, Volume: 193 Topics: Acetohexamide; Chlorpropamide; Diabetes Mellitus; Drug Therapy; Glucose; Hypoglycemic Agents; Pharmacology; Phenformin; Tolbutamide	1965
A convenient five-drug cocktail for the assessment of major drug metabolizing enzymes: a pilot study. British journal of clinical pharmacology, 2004, Volume: 58, Issue:3 Topics: Adult; Caffeine; Chlorzoxazone; Cytochrome P-450 Enzyme System; Dapsone; Drug Combinations; Humans; Male; Metoprolol; Phenformin; Pilot Projects; Tolbutamide	2004