tolbutamide has been researched along with pentobarbital in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 2 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Carulli, N; Ferrari, A; Gallo, M; Manenti, F; Ponz de Leon, M; Salvioli, G | 1 |
| Black, M | 1 |
| Darby, FJ | 1 |
| Darby, J | 1 |
| Bacci, MC; Bianchi, C; Bonardi, G; Coppi, G; Molino, C; Tomasi, L; Vidi, A | 1 |
| Aggarwal, V; Sunshine, I | 1 |
| Jahns, R; Poser, W | 1 |
| Brendel, K; Bressler, R; Kizer, JS; Vargas-Gordon, M | 1 |
| Clancy, BA; Iber, FL; Shah, MN | 1 |
| Darby, FJ; Evans, DA; Grundy, RK | 1 |
| Darby, FJ; Evans, DA | 2 |
2 review(s) available for tolbutamide and pentobarbital
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Liver disease and drug therapy.
Topics: Amobarbital; Azathioprine; Half-Life; Humans; Lidocaine; Liver Cirrhosis; Liver Diseases; Metabolic Clearance Rate; Niridazole; Pentobarbital; Pharmaceutical Preparations; Phenylbutazone; Prednisone; Schistosomiasis; Sulfur Radioisotopes; Tolbutamide | 1974 |
14 other study(ies) available for tolbutamide and pentobarbital
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Alteration of drug metabolism during cholestasis in man.
Topics: Adolescent; Adult; Aged; Cholestasis; Female; Half-Life; Hepatitis; Humans; Liver; Male; Meprobamate; Middle Aged; Pentobarbital; Tolbutamide | 1975 |
Inhibition by ethylmorphine and pentobarbitone in vitro of the metabolism of (ureyl- 14 C)tolbutamide by hepatic microsomal preparations from male and female rats treated with phenobarbitone.
Topics: Animals; Carbon Isotopes; Depression, Chemical; Female; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Morphinans; Pentobarbital; Phenobarbital; Rats; Sex Factors; Tolbutamide | 1972 |
Inhibition by ethylmorphine and pentobarbitone in vitro of the metabolism of (ureyl- 14 C)tolbutamide by hepatic microsomal preparations from sexually-immature male and female rats treated with phenobarbitone.
Topics: Animals; Carbon Isotopes; Female; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Morphinans; Pentobarbital; Phenobarbital; Rats; Sex Factors; Tolbutamide | 1973 |
Experimental models for the in vivo evaluation of enzyme induction properties of drugs.
Topics: Acetanilides; Amides; Aminopyrine; Amphetamine; Aniline Compounds; Animals; Central Nervous System; Codeine; Cyclohexanecarboxylic Acids; Drug Evaluation, Preclinical; Enzyme Activation; Enzyme Induction; Hexobarbital; Male; Meperidine; Mice; Oxotremorine; Pentobarbital; Phenacetin; Phenytoin; Rabbits; Rats; Strychnine; Tolbutamide; Tremorine; Zoxazolamine | 1973 |
Determination of sulfonylureas and metabolites by pyrolysis gas chromatography.
Topics: Amobarbital; Chlorobenzenes; Chlorpropamide; Chromatography, Gas; Evaluation Studies as Topic; Humans; Mass Spectrometry; Methods; Pentobarbital; Phenobarbital; Secobarbital; Structure-Activity Relationship; Sulfonamides; Sulfonylurea Compounds; Time Factors; Tolazamide; Tolbutamide | 1974 |
[A simplified method for functional hepatectomy].
Topics: Ammonia; Animals; Blood Glucose; Hepatectomy; Hypoglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Jugular Veins; Methods; Pentobarbital; Portal Vein; Rats; Tolbutamide | 1967 |
The in vitro inhibition of insulin secretion by diphenylhydantoin.
Topics: Animals; Anticonvulsants; Buffers; Glucose; Hydantoins; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Methacholine Compounds; Ouabain; Pancreas; Pentobarbital; Phenytoin; Potassium; Rats; Tolbutamide | 1970 |
Comparison of blood clearance of ethanol and tolbutamide and the activity of hepatic ethanol-oxidizing and drug-metabolizing enzymes in chronic alcoholic subjects.
Topics: Adult; Alcohol Oxidoreductases; Alcoholism; Aniline Compounds; Chronic Disease; Ethanol; Half-Life; Humans; Liver; Metabolic Clearance Rate; Microsomes, Liver; Mixed Function Oxygenases; Pentobarbital; Time Factors; Tolbutamide | 1972 |
Apparent Michaelis constants for the metabolism of (ureyl- 14 C)tolbutamide by human liver microsomal preparations.
Topics: Animals; Autopsy; Biopsy; Carbon Isotopes; Female; Humans; Hydroxylation; Kinetics; Male; Microsomes, Liver; Organ Culture Techniques; Pentobarbital; Rats; Time Factors; Tolbutamide; Urea | 1972 |
The metabolism in vitro of (ureyl-14C)-tolbutamide by microsomal preparations from rat and human liver.
Topics: Animals; Autopsy; Biopsy; Depression, Chemical; Humans; In Vitro Techniques; Kinetics; Microsomes, Liver; Morphinans; Pentobarbital; Rats; Tolbutamide | 1971 |
(Ureyl- 14 C) tolbutamide and (2- 14 C) pentobarbitone as substrates for the hepatic microsomal drug-metabolizing enzyme system in vitro.
Topics: Animals; Carbon Isotopes; Depression, Chemical; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Pentobarbital; Rats; Tolbutamide | 1971 |