Page last updated: 2024-08-16

tolbutamide and nitrendipine

tolbutamide has been researched along with nitrendipine in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19904 (21.05)18.7374
1990's2 (10.53)18.2507
2000's5 (26.32)29.6817
2010's8 (42.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Calle, R; Ganesan, S; Rasmussen, H; Zawalich, KC; Zawalich, WS1
Zawalich, WS1
Zawalich, KC; Zawalich, WS1
Diaz, VA; Zawalich, KC; Zawalich, WS1
Diaz, VA; Rasmussen, H; Takuwa, N; Takuwa, Y; Zawalich, W1
Kikuchi, M; Nakata, M; Sakurada, M; Yada, T; Yaekura, K1
Srinivas, NR1

Other Studies

19 other study(ies) available for tolbutamide and nitrendipine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Effects of the phorbol ester phorbol 12-myristate 13-acetate (PMA) on islet-cell responsiveness.
    The Biochemical journal, 1991, Aug-15, Volume: 278 ( Pt 1)

    Topics: Animals; Calcimycin; Calcium; Glucose; Immunoblotting; Inositol; Inositol Phosphates; Insulin; Insulin Secretion; Islets of Langerhans; Male; Nitrendipine; Phosphatidylinositols; Potassium; Protein Kinase C; Rats; Rats, Inbred Strains; Sincalide; Tetradecanoylphorbol Acetate; Tolbutamide

1991
Phosphoinositide hydrolysis and insulin secretion in response to glucose stimulation are impaired in isolated rat islets by prolonged exposure to the sulfonylurea tolbutamide.
    Endocrinology, 1989, Volume: 125, Issue:1

    Topics: Animals; Glucose; Glycerides; Hydrolysis; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Male; Nitrendipine; Phosphatidylinositols; Rats; Rats, Inbred Strains; Stimulation, Chemical; Sulfonylurea Compounds; Time Factors; Tolbutamide

1989
Induction of memory in rat pancreatic islets by tolbutamide. Dependence on ambient glucose level, calcium, and phosphoinositide hydrolysis.
    Diabetes, 1988, Volume: 37, Issue:6

    Topics: Animals; Calcium; Glucose; Hydrolysis; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Nitrendipine; Phosphatidylinositols; Rats; Rats, Inbred Strains; Time Factors; Tolbutamide

1988
Influence of cAMP and calcium on [3H]inositol efflux, inositol phosphate accumulation, and insulin release from isolated rat islets.
    Diabetes, 1988, Volume: 37, Issue:11

    Topics: Animals; Calcium; Colforsin; Cyclic AMP; Glucose; Hydrolysis; Inositol; Inositol Phosphates; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Nitrendipine; Phosphatidylinositols; Rats; Rats, Inbred Strains; Sincalide; Sugar Phosphates; Theophylline; Tolbutamide

1988
Interactions of cholecystokinin and glucose in rat pancreatic islets.
    Diabetes, 1987, Volume: 36, Issue:4

    Topics: Animals; Cholecystokinin; Colforsin; Glucose; Inositol; Insulin; Insulin Secretion; Islets of Langerhans; Male; Nitrendipine; Phosphatidylinositols; Rats; Rats, Inbred Strains; Tolbutamide

1987
PACAP as low as 10(-13) M raises cytosolic Ca2+ activity in pancreatic B-cells by augmenting Ca2+ influx through L-type Ca2+ channels to trigger insulin release.
    Advances in experimental medicine and biology, 1997, Volume: 426

    Topics: Animals; Calcium; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Neuropeptides; Neurotransmitter Agents; Nitrendipine; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Wistar; Tolbutamide

1997
Is pomegranate juice a potential perpetrator of clinical drug-drug interactions? Review of the in vitro, preclinical and clinical evidence.
    European journal of drug metabolism and pharmacokinetics, 2013, Volume: 38, Issue:4

    Topics: Animals; Anti-Anxiety Agents; Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Beverages; Buspirone; Caco-2 Cells; Calcium Channel Blockers; Carbamazepine; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Evaluation, Preclinical; Drug Interactions; Flurbiprofen; Food-Drug Interactions; Humans; Hypnotics and Sedatives; Hypoglycemic Agents; Lythraceae; Midazolam; Nitrendipine; Tolbutamide; Triazolam

2013