Page last updated: 2024-08-16

tolbutamide and mercaptopurine

tolbutamide has been researched along with mercaptopurine in 15 studies

Research

Studies (15)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (20.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	5 (33.33)	29.6817
2010's	7 (46.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Khekht, A; Shimelpfenig, R; Shimelpfenig, V; Shnaider, G; Toier, D; Vagner, K	1
Tuchmann-Duplessis, H	1
Gulati, OD; Patel, DG	1
Hiratsuka, M	1

Reviews

2 review(s) available for tolbutamide and mercaptopurine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Development of simplified and rapid detection assay for genetic polymorphisms influencing drug response and its clinical applications]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2002, Volume: 122, Issue:7 Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Arylamine N-Acetyltransferase; Biotransformation; Cytochrome P-450 Enzyme System; DNA, Mitochondrial; Genotype; Humans; Isoniazid; Male; Mercaptopurine; Methyltransferases; Pharmacogenetics; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Tolbutamide	2002

Article

Year

DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.

Drug discovery today, 2016, Volume: 21, Issue:4

Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

[Development of simplified and rapid detection assay for genetic polymorphisms influencing drug response and its clinical applications].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2002, Volume: 122, Issue:7

Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Arylamine N-Acetyltransferase; Biotransformation; Cytochrome P-450 Enzyme System; DNA, Mitochondrial; Genotype; Humans; Isoniazid; Male; Mercaptopurine; Methyltransferases; Pharmacogenetics; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Tolbutamide

2002

Other Studies

13 other study(ies) available for tolbutamide and mercaptopurine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
[Experience with immunosuppressive therapy in chronic aggressive hepatitis]. Vutreshni bolesti, 1972, Volume: 11, Issue:3 Topics: Autoimmune Diseases; Azathioprine; Hepatitis; Humans; Immunosuppressive Agents; Mercaptopurine; Prednisone; Tolbutamide	1972
[The teratogenic risk]. Archives d'anatomie, d'histologie et d'embryologie normales et experimentales, 1968, Volume: 51, Issue:5 Topics: Abnormalities, Drug-Induced; Animals; Azathioprine; Busulfan; Carbutamide; Congenital Abnormalities; Cyclophosphamide; Female; Gestational Age; Humans; Lipid Metabolism; Maternal Age; Measles; Mercaptopurine; Mice; Morphogenesis; Pregnancy; Pregnancy Complications; Pregnancy Complications, Infectious; Radiation Injuries; Rats; Thalidomide; Tolbutamide	1968
Effects of various drugs on insulin antibodies. British journal of pharmacology, 1971, Volume: 42, Issue:1 Topics: Animals; Antibodies; Antineoplastic Agents; Bromouracil; Chlorambucil; Chlorpropamide; Complement Fixation Tests; Cyclophosphamide; Dactinomycin; Diaphragm; Diethylstilbestrol; Drug Synergism; Female; Fluorouracil; Gonadal Steroid Hormones; Guinea Pigs; Hydrocortisone; Injections, Intraperitoneal; Injections, Subcutaneous; Insulin Antibodies; Male; Mercaptopurine; Methotrexate; Neutralization Tests; Phenformin; Testosterone; Tolbutamide; Triazines	1971