tolbutamide has been researched along with leucine in 185 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 175 (94.59) | 18.7374 |
1990's | 9 (4.86) | 18.2507 |
2000's | 1 (0.54) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Grill, V; Rundfeldt, M | 1 |
Di Campo-Rougerie, C; Ramahandridona, G; Vague, P | 1 |
Berger, H | 1 |
Fischer, LJ; Rickert, DE | 1 |
Adcock, K; Austin, M; Duckworth, WC; Murrell, LR; Solomon, SS | 1 |
Garcia, SD; Jarrousse, C; Rosselin, G | 1 |
Macchi, IA; Zeytinoğlu, FN | 1 |
Ashcroft, SJ | 1 |
Kreines, K; Mako, ME; Starr, JI | 1 |
Come, SE; Eastman, RC; Gorden, P; Kahn, CR; Strewler, GJ | 1 |
Arends, J; Frerichs, H; Schauder, P | 1 |
Hudson, AJ; Tevaarwerk, GJ | 1 |
Arimura, A; Dobbs, RE; Harris, V; Ipp, E; Unger, RH; Vale, W | 1 |
Anderson, JH; Blackard, WG | 1 |
Boquist, L | 2 |
Di Campo-Rougerie, C; Mahmoud, F; Ramahandridona, G; Vague, P | 1 |
Alberti, KG; Marks, V | 1 |
Ogawa, S; Yoshinaga, T | 1 |
Levy, J; Malaisse, WJ | 1 |
Parman, AU | 1 |
Frerichs, H; Schauder, P | 1 |
Couropmitree, C; Freinkel, N; Hahnel, R; Horwitz, DL; Metzger, B; Nagel, TC; Rubenstein, AH | 1 |
Aarskog, D; Fluge, G; Stoa, KF | 1 |
Krämer, K; Sailer, FX | 1 |
Horwitz, DL; Kuzuya, H; Rubenstein, AH; Sandler, R | 1 |
Förster, VH | 1 |
Rathanaswami, P; Sundaresan, R | 2 |
Bedoya, FJ; Jeanrenaud, B | 1 |
Field, JB | 1 |
Ashford, ML; Carrington, CA; Hales, CN; Kozlowski, RZ; Sturgess, NC | 1 |
Henquin, JC; Hermans, MP; Schmeer, W | 1 |
Wolff, G | 2 |
Hodgins, DS; Kuo, JF; Kuo, WN | 1 |
Hellman, B; Sehlin, J; Täljedal, IB | 1 |
Ashcroft, SJ; Randle, PJ; Weerasinghe, LC | 1 |
Dunbar, JC; Foà, PP | 1 |
Dean, PM; Matthews, EK | 2 |
Mashimo, K; Nakagawa, M | 1 |
Miles, LE | 1 |
Drash, A; Schultz, R | 1 |
Lundbaek, K; Lyngsoe, J; Madsen, B; Orskov, H; Yde, H | 1 |
Greenwood, FC; Howorth, PJ; Marks, V; Samols, E | 1 |
Grumbach, MM; Kaplan, SL; Schotland, MG | 1 |
Lebovitz, HE; Pooler, K | 1 |
Antony, GJ; Underwood, LE; Van Wyk, JJ | 1 |
Smith, M | 1 |
Colwell, JA; Furey, WL | 1 |
Hung, W; Migeon, CJ | 1 |
Frawley, TF; Pensuwan, S | 1 |
Howell, SL; Taylor, KW | 1 |
Glöckner, E; Knoke, M; Markert, J; Reding, R | 1 |
Etheridge, JE | 1 |
Conn, JW; Fajans, SS; Floyd, JC; Harrison, TS; Knopf, RF; Thiffault, CA | 1 |
Sleisenger, MH; Walsh, JH | 1 |
Marks, V; Samols, E | 1 |
Dorner, M; Fontaine, R; Haarscher, A; Hasselmann, JL; Levy-Silagy, J; Schneegans, E | 1 |
Bryson, GH; Hume, DM; Williams, C | 1 |
Blaskovics, M; Donnell, GN; Kogut, MD | 1 |
Williams, C | 1 |
Abernethy, RJ; Buchanan, KD; McKiddie, MT | 1 |
Caquet, R | 1 |
Pi-Sunyer, FX; Van Itallie, TB; Zintel, HA | 1 |
DePeyster, FA | 1 |
Brooten, P; Felig, P; Landsberg, L; Sachs, FL | 1 |
Grinvalsky, HT; Remigio, PA | 1 |
Parmentier, J; Rubay, J | 1 |
Schwartz, JF; Zwiren, GT | 1 |
Cunningham, GR; Lebovitz, HE; Quickel, KE | 1 |
Gorden, P; Roth, J; Sherman, B | 1 |
Ashworth, MA; Milner, RD | 1 |
Marks, V | 1 |
Levey, GS; Mintz, DH; Schmidt, WM | 2 |
Corredor, DG; Danowski, TS; Dhawer, VP; Gonzalez, AR; Jung, Y; Khurana, RC; Klayton, R; Sieracki, JC | 1 |
Baker, L; Balsam, MJ; Bishop, HC; Hummeler, K; Kaye, R; Yakovac, WC | 1 |
Freinkel, N; Knopp, RH; Scheinin, JC | 1 |
Birchard, E; Cameron, GS; Cole, FM; Tuttle, RJ; Wright, AD | 1 |
Manusharova, RA; Nikolaev, OV; Veinberg, EG | 1 |
Howell, SL; Montague, W | 1 |
Basoli, A; Carboni, M; De Bernardinis, G; Patrassi, N; Perrotta, G | 1 |
Alsever, RN; Stjernholm, MR | 1 |
Lefebvre, P; Luyckx, A | 1 |
Ishihara, Y; Kuroda, A; Sato, N; Tajima, Y; Wada, Y | 1 |
Grögler, F; Lucke, C; Mitzkat, HJ | 1 |
Shapiro, JR; Sotoudeh, F | 1 |
Antony, GJ; Underwood, LE; Van den Brande, JL; Van Wyk, JJ; Voina, SJ | 1 |
Hirata, Y | 1 |
Gerich, J; Grodsky, GM; Karam, J; Levin, S; Sando, H | 1 |
Henquin, JC; Lambert, AE; Orci, L; Renold, AE | 1 |
Hinz, M; Maier, V; Nierle, C; Pfeiffer, EF; Schatz, H | 1 |
Tjioe, TO; Wacker, A | 1 |
Colle, E; Schiff, D; Stern, L; Wells, D | 1 |
Danowski, TS; Khurana, RC; Klayton, R; Nolan, S; Stephan, T | 1 |
Lavis, V; Sakai, T; Williams, RH | 1 |
Duprey, J; Lubetzki, J | 1 |
Blackard, WG; Kikuchi, M; Rabinovitch, A; Renold, AE | 1 |
Barbosa, J; Goetz, F; Kennedy, W; Nuttall, FQ | 1 |
Huff, TA; Lebovitz, HE | 1 |
Edgar, P; Merimee, TJ; Rabinowitz, D | 1 |
Isshiki, G; Ogawa, S; Okuno, G; Ueda, T; Yoshinaga, T | 1 |
Baker, RJ | 1 |
Costamaillere, L | 1 |
Hellerström, C; Schmidt, FH; Stork, H; Westman, S | 1 |
Haist, RE; Lin, BJ | 1 |
Hales, CN; Milner, RD | 3 |
Balant, L; Burr, IM; Grodsky, GM; Renold, AE; Stauffacher, W | 1 |
Misugi, K; Misugi, N; Smith, B; Sotos, J | 1 |
Korner, A; Morris, GE | 1 |
Wüstenberg, PW | 1 |
Chandra, P; Wacker, A; Wacker, D | 1 |
Christensen, HN; Tager, HS | 1 |
Underwood, LE; Van Wyk, JJ; Voina, SJ | 1 |
Aozi, O; Fujii, M; Okumura, K; Yokoo, S; Yoshida, H | 1 |
Aust, S; Theile, H | 1 |
Junod, A; Lambert, AE; Letarte, J; Stauffacher, W | 1 |
Kowalski, H; Lawecki, J; Rogala, H | 1 |
Mahler, RJ; Szabo, O | 1 |
Andreani, D; Fallucca, F; Javicoli, M; Tamburrano, G | 1 |
Basabe, JC; Lopez, NL; Viktora, JK; Wolff, FW | 1 |
Ambs, E; Brunnberg, J; Gekle, D | 1 |
Albeaux-Fernet, M | 1 |
Federspil, G; Frezzato, S; Macrì, C; Muggeo, M; Tiengo, A; Trisotto, A; Vianello, A | 1 |
Aylor, KW; Parry, DG | 1 |
DeChatelet, LR; McDonald, HJ | 4 |
Chiumello, G; Drash, A; Kenny, FM | 1 |
Farquhar, JW; Frank, A; Reaven, GM | 1 |
Christensen, HN; Cullen, AM | 1 |
Ehrlich, RM; Martin, JM | 1 |
Paulsen, EP; Velasco, MS | 1 |
Teller, W | 1 |
Friend, JA; Hales, CN | 1 |
Conason, EG; Most, S; Podolsky, S; Rifkin, H; Ross, H | 1 |
Colwell, AR | 1 |
Penttilä, IM | 1 |
Kenny, FM; Preeyasombat, C | 1 |
Correia, JP; DeMoura, MC; Madeira, F | 1 |
De Schepper, PJ | 1 |
Gishizky, ML; Gold, G; Grodsky, GM | 1 |
Abdel-Hamid, M; Ammon, HP; Enz, G; Rao, PG | 1 |
Henquin, JC; Tamagawa, T | 1 |
Bailbe, D; Giroix, MH; Kergoat, M; Picon, L; Portha, B | 1 |
Böhles, H | 1 |
Barnett, DW; Chern, HT; Misler, S; Pressel, DM; Scharp, DW | 1 |
Gross, R; Hillaire-Buys, D; Manteghetti, M; Ribes, G; Roye, M | 1 |
Martin, F; Reig, JA; Soria, B | 1 |
Bell, DA; Birkett, DJ; Ghanayem, BI; Goldstein, JA; Kaminsky, LS; Miners, JO; Shenfield, GM; Sullivan-Klose, TH; Zhang, ZY | 1 |
Hosaka, T; Oka, Y | 1 |
Balamurugan, AN; Gunasekaran, S; Ramakrishna, B | 1 |
Clark, A; de Koning, EJ; MacArthur, DL; Morris, JF; Verbeek, JS | 1 |
BALASH, WR; BONESSI, JV; DANOWSKI, TS; MOSES, C | 1 |
BONESSI, JV; DANOWSKI, TS; MOSES, C | 1 |
BRADHAM, R; BUSE, J; BUSE, MG; MARSHALL, JN; OBERMAN, H | 1 |
FRAWLEY, TF; PENSUWAN, S; YERRY, R; ZACHAREWICZ, F | 1 |
LANDON, J; SAMOLS, E; WYNN, V | 1 |
GERSHBERG, H; NADLER, HL; NEUMANN, LL | 1 |
BOSHELL, BR; KIRSCHENFELD, JJ; SOTERES, PS | 1 |
BAENS, GS; CORNBLATH, M; WYBREGT, SH | 1 |
BUTTERFIELD, WJ; JARRETT, RJ | 1 |
BOUMAN, PR | 1 |
CARNEVALI, R; POLI, E; RAINERI, P | 1 |
COLES, HM | 1 |
BAENS, GS; CORNBLATH, M; KLEIN, RI; WYBREGT, SH | 1 |
GRANN, V; MAHLER, RJ; PURDY, R | 1 |
LEVINE, R; MAHLER, R | 1 |
SCHOLTZ, DA | 1 |
BIELIK, E; GALIK, L; HRNCIAR, J; HRNCIAROVA, M | 1 |
FOA, PP | 1 |
AKIYAMA, Y; ISHIGAMI, R; KWATA, T; NATORI, H; OHMOTO, J; OKADA, H; SHIOTANI, S; YOSHIDA, A | 1 |
CONN, JW; FAJANS, SS; FLOYD, JC; KNOPF, RF | 1 |
EYMONTT, MJ; GWINUP, G; HAMWI, GJ; KRUGER, FA; MAYNARD, DE | 1 |
KELLEY, VC; RUVALCABA, RH; SAMOLS, E | 1 |
GINSBERG, DM | 1 |
CLARKE, DW; EHRLICH, R; EVANS, J; FORBATH, N; VOLPE, R | 1 |
Hoe, FM; Simmons, RA; Stanley, CA; Steinkrauss, L; Thornton, PS; Wanner, LA | 1 |
23 review(s) available for tolbutamide and leucine
Article | Year |
---|---|
The control of insulin release by sugars.
Topics: Acetylglucosamine; Animals; Caffeine; Calcium; Carbohydrates; Cyclic AMP; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Leucine; Mice; Perfusion; Potassium; Rats; Receptors, Drug; Starvation; Tolbutamide | 1976 |
Selected tests of carbohydrate metabolism.
Topics: Adolescent; Adult; Blood Glucose; Carbohydrate Metabolism; Child; Clinical Laboratory Techniques; Diazoxide; Fasting; Female; Fructose; Galactose; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Inulin; Lactose; Leucine; Male; Middle Aged; Proinsulin; Time Factors; Tolbutamide | 1976 |
Hypoglycemia. Definition, clinical presentations, classification, and laboratory tests.
Topics: Blood Glucose; Calcium; Fever; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Hypothermia; Insulin; Leucine; Nervous System Diseases; Tolbutamide | 1989 |
[Hypoglycemia. 3].
Topics: Animals; Arginine; Biguanides; Diazoxide; Dicumarol; Drug Synergism; Ethanol; Glucagon; Glucocorticoids; Glucose; Guinea Pigs; Humans; Hypoglycemia; Hypoglycemic Agents; Leucine; Mice; Rabbits; Rats; Sympatholytics; Tolbutamide; Xylitol | 1970 |
Hypoglycemia: tolbutamide and leucine tests in insulinoma.
Topics: Adenoma, Islet Cell; Blood Glucose; Fasting; Female; Glucagon; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemia; Insulin; Insulin Secretion; Leucine; Male; Middle Aged; Pancreatic Neoplasms; Tolbutamide | 1968 |
Hypoglycemia and the central nervous system.
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Brain; Child, Preschool; Diazoxide; Diet Therapy; Epinephrine; Fasting; Glucagon; Glucose; Glucose Tolerance Test; Humans; Hypoglycemia; Hypoxia; Infant; Infant, Newborn; Infant, Newborn, Diseases; Insulin; Leucine; Oxygen Consumption; Seizures; Tolbutamide; Zinc | 1967 |
Functioning tumors of the pancreas.
Topics: Adenoma, Islet Cell; Diarrhea; Digestive System; Fasting; Gastrins; Glucagon; Glucose; Glucose Tolerance Test; Humans; Hypoglycemia; Hypokalemia; Leucine; Pancreatic Neoplasms; Tolbutamide; Zollinger-Ellison Syndrome | 1968 |
Progress report. Diagnosis of insulinoma.
Topics: Adenoma, Islet Cell; Angiography; Blood Glucose; Child; Child, Preschool; Diagnosis, Differential; Ethanol; Fasting; Glucagon; Glucose Tolerance Test; Hormones, Ectopic; Humans; Hypoglycemia; Infant; Infant, Newborn; Injections, Intravenous; Insulin; Leucine; Pancreatic Neoplasms; Parathyroid Neoplasms; Pituitary Neoplasms; Tolbutamide | 1971 |
Diazoxide and the secretion of insulin.
Topics: Animals; Cyclic AMP; Diazoxide; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Pancreas; Perfusion; Rats; Theophylline; Tolbutamide | 1972 |
[Insulinoma].
Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Angiography; Child; Diagnosis, Differential; Diagnostic Techniques, Surgical; Female; Glucagon; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemia; Insulin; Leucine; Male; Middle Aged; Pancreatic Neoplasms; Proinsulin; Tolbutamide | 1973 |
[Hypoglycemia].
Topics: Blood Glucose; Ethanol; Fasting; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Iatrogenic Disease; Insulin; Insulin Antibodies; Leucine; Tolbutamide | 1972 |
Synthesis and secretion of insulin in dynamic perfusion systems.
Topics: Animals; Antimetabolites; Arginine; Carbon Radioisotopes; Computers; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Isotope Labeling; Leucine; Models, Biological; Obesity; Oligomycins; Pancreas; Perfusion; Rats; Time Factors; Tolbutamide | 1974 |
[Hypoglycemia. 3].
Topics: Biguanides; Cyclophosphamide; Diet, Diabetic; Ethanol; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Leucine; Plant Poisoning; Sulfonamides; Sympathomimetics; Tolbutamide | 1968 |
Newer considerations in the diagnosis and management of fasting hypoglycemia.
Topics: Adult; Blood Glucose; Catecholamines; Celiac Artery; Child, Preschool; Fasting; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Leucine; Liver Function Tests; Radiography; Radioisotopes; Radionuclide Imaging; Selenium; Tolbutamide | 1969 |
[Spontaneous hypoglycemias].
Topics: Ethanol; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Leucine; Tolbutamide | 1969 |
[The hypoglycemia syndrome].
Topics: Alloxan; Angiography; Antibiotics, Antineoplastic; Blood Glucose; Diagnosis, Differential; Diazoxide; Diet Therapy; Epinephrine; Gastrointestinal Diseases; Glucagon; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemia; Leucine; Metabolic Diseases; Neoplasms; Pancreatic Neoplasms; Prednisone; Tolbutamide | 1970 |
[The diagnosis of hypoglycemia in childhood (author's transl)].
Topics: Adolescent; Age Factors; Alanine; Child; Child, Preschool; Deoxyglucose; Glucagon; Glucose Tolerance Test; Hepatomegaly; Humans; Hypoglycemia; Infant; Infant, Newborn; Leucine; Time Factors; Tolbutamide | 1980 |
[Tolbutamide, glucagon, leucine and arginine tolerance test].
Topics: Arginine; Diabetes Mellitus; Glucagon; Humans; Hypoglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Pancreatic Function Tests; Tolbutamide | 1997 |
[POSSIBILITIES AND LIMITATIONS IN THE DETERMINATION OF INSULIN IN BLOOD IN THE DIAGNOSIS OF HYPERINSULINISM].
Topics: Adenoma, Islet Cell; Blood; Diagnosis; Humans; Hyperglycemia; Hyperinsulinism; Insulin; Leucine; Pancreatic Neoplasms; Tolbutamide | 1963 |
PRODUCTION, SECRETION, AND AVAILABILITY OF INSULIN.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Blood Chemical Analysis; Chemical Phenomena; Chemistry; Growth Hormone; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Antibodies; Leucine; Metabolism; Tolbutamide | 1964 |
[HYPERINSULINISM. DIAGNOSTIC AND THERAPEUTIC ASPECTS].
Topics: Diagnosis, Differential; Electrodiagnosis; Electroencephalography; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemia; Leucine; Pancreas; Sleep Wake Disorders; Surgical Procedures, Operative; Tolbutamide | 1964 |
EXPERIMENTAL DIABETES AND THE MODE OF ACTION OF THE SULFONYLUREAS. WITH SOME SPECULATIONS ON THE PREVENTION OF DIABETES.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Animals; Cortisone; Diabetes Mellitus; Diabetes Mellitus, Experimental; Fatty Acids; Fluoroacetates; Genetics, Medical; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; Hypoglycemic Agents; Leucine; Pharmacology; Pregnancy; Prolactin; Rats; Research; Sulfonylurea Compounds; Tolbutamide | 1964 |
HYPOGLYCEMIA ASSOCIATED WITH EXTRAPANCREATIC NEOPLASMS, WITH A NOTE ON OTHER UNUSUAL FORMS OF HYPOGLYCEMIA.
Topics: Adrenogenital Syndrome; Carcinoma, Hepatocellular; Drug Therapy; Glycogen Storage Disease Type I; Humans; Hypoglycemia; Leucine; Liver Glycogen; Liver Neoplasms; Mesenchymoma; Neoplasms; Retroperitoneal Neoplasms; Thoracic Neoplasms; Tolbutamide | 1964 |
1 trial(s) available for tolbutamide and leucine
Article | Year |
---|---|
The use of insulin dynamics in the evaluation of streptozotocin therapy of malignant insulinomas.
Topics: Adenoma, Islet Cell; Adult; Alkaline Phosphatase; Antibiotics, Antineoplastic; Aspartate Aminotransferases; Blood Glucose; Carbon Dioxide; Chlorides; Clinical Trials as Topic; Female; Glucose Tolerance Test; Hematocrit; Humans; Insulin; Insulin Secretion; Leucine; Leukocyte Count; Middle Aged; Potassium; Sodium; Specific Gravity; Sulfobromophthalein; Tolbutamide; Urine | 1971 |
161 other study(ies) available for tolbutamide and leucine
Article | Year |
---|---|
Effects of priming with D-glucose on insulin secretion from rat pancreatic islets: increased responsiveness to other secretagogues.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Alloxan; Animals; Barium; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Perfusion; Rats; Tolbutamide | 1979 |
[Effect of glucose and of insulin on the fast induced decrease of insulin response to glucose of the in vitro perfused rat pancreas].
Topics: Animals; Fasting; Glucose; Insulin; Insulin Secretion; Leucine; Male; Pancreas; Perfusion; Rats; Secretory Rate; Stimulation, Chemical; Tolbutamide | 1975 |
Hypoglycemia: a perspective.
Topics: Adenoma, Islet Cell; Citric Acid Cycle; Diabetes Complications; Diazoxide; Female; Glucose; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemia; Insulin; Leucine; Liver; Liver Diseases; Middle Aged; Muscles; Pancreatic Neoplasms; Streptozocin; Tolbutamide | 1975 |
Cyproheptadine and beta cell function in the rat: insulin secretion from pancreas segments in vitro.
Topics: Administration, Oral; Animals; Bucladesine; Cyproheptadine; Dose-Response Relationship, Drug; Glucagon; Glucose; In Vitro Techniques; Injections, Intraperitoneal; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Rats; Tolbutamide | 1975 |
Human islet cell adenoma: metabolic analysis of the patient and of tumor cells in monolayer culture.
Topics: Adenoma, Islet Cell; Adult; Cell Survival; Cells, Cultured; Culture Media; Cyclic AMP; Glucagon; Glucose; Humans; In Vitro Techniques; Insulin; Insulin Secretion; Leucine; Male; Proinsulin; Theophylline; Tolbutamide | 1975 |
Biosynthesis of proinsulin and insulin in newborn rat pancreas. Interaction of glucose, cyclic AMP, somatostatin, and sulfonylureas on the (3H) leucine incorporation into immunoreactive insulin.
Topics: Animals; Animals, Newborn; Antigens; Cyclic AMP; Glipizide; Glucose; Humans; Insulin; Islets of Langerhans; Leucine; Proinsulin; Rats; Somatostatin; Sulfonylurea Compounds; Theophylline; Tolbutamide | 1976 |
Hyaluronidase-induced inhibition of the insulinotropic action of sulfonylureas, leucine, and glucagon in rodent isolated pancreatic islets.
Topics: Animals; Chlorpropamide; Cricetinae; Female; Glucagon; Glucose; Glyburide; Hyaluronoglucosaminidase; Insulin; Islets of Langerhans; Leucine; Mice; Microbial Collagenase; Rats; Species Specificity; Sulfonylurea Compounds; Tolbutamide | 1976 |
Insulin and proinsulin metabolism in an unusual case of insulinoma.
Topics: Adenoma, Islet Cell; Glucagon; Glucose Tolerance Test; Humans; Insulin; Leucine; Male; Middle Aged; Proinsulin; Tolbutamide | 1976 |
Adriamycin therapy for advanced insulinoma.
Topics: Adenoma, Islet Cell; Adult; Blood Glucose; Diazoxide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Glucagon; Humans; Insulin; Leucine; Male; Middle Aged; Prednisone; Streptozocin; Tolbutamide | 1977 |
Onset and reversibility of changes in secretory function and composition of isolated rat pancreatic islets following long-term administrationof high or low tolbutamide doses.
Topics: Animals; Blood Glucose; Glucagon; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Leucine; Male; Rats; Theophylline; Time Factors; Tolbutamide | 1977 |
Carbohydrate metabolism and insulin resistance in myotonia dystrophica.
Topics: Adult; Aged; Arginine; Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus; Female; Fructose; Galactose; Glucagon; Glucose Tolerance Test; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Leucine; Male; Middle Aged; Myotonic Dystrophy; Sorbitol; Tolbutamide; Xylose | 1977 |
Release of immunoreactive somatostatin from the pancreas in response to glucose, amino acids, pancreozymin-cholecystokinin, and tolbutamide.
Topics: Amino Acids; Animals; Antigens; Cholecystokinin; Dogs; Glucose; Islets of Langerhans; Leucine; Male; Somatostatin; Tolbutamide | 1977 |
Effect of lithium on pancreatic islet insulin release.
Topics: Animals; Calcium; Choline; Culture Techniques; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Lithium; Male; Rats; Tolbutamide | 1978 |
Differences in the blood glucose response of mice to alloxan and alloxan-inhibiting compounds.
Topics: Acetazolamide; Alloxan; Animals; Bicarbonates; Blood Glucose; Deoxy Sugars; Diabetes Mellitus, Experimental; Eating; Hydroxymercuribenzoates; Lactates; Leucine; Mannoheptulose; Mice; Mice, Inbred C57BL; Phenytoin; Starvation; Tolbutamide | 1979 |
Kinetics of the early insulin response of the perfused rat pancreas to various metabolites and tolbutamide.
Topics: Animals; Caproates; Glucose; Glyceraldehyde; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Rats; Stimulation, Chemical; Time Factors; Tolbutamide; Valerates | 1975 |
Electron microscopic study on zinc in B cells of pancreatic islets of rat under conditions stimulating the excretion of insulin.
Topics: Animals; Chlorpropamide; Cytoplasmic Granules; Glucose; Histocytochemistry; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Protein Binding; Rats; Sulfides; Tolbutamide; Zinc | 1975 |
The stimulus-secretion coupling of glucose-induced insulin release-XVII. Effects of sulfonylureas and diazoxide on insular biosynthetic activity.
Topics: Animals; Cyclohexanes; Cyclopentanes; Diazoxide; Glucose; Hormones; In Vitro Techniques; Insulin; Islets of Langerhans; Leucine; Oxidation-Reduction; Peptide Biosynthesis; Proinsulin; Pyrazines; Pyrroles; Rats; Sulfonylurea Compounds; Tolbutamide | 1975 |
Effects of hypophysectomy and short-term growth hormone replacement on insulin release from and glucose metabolism in isolated rat islets of Langerhans.
Topics: Adrenal Glands; Animals; Arginine; Blood Urea Nitrogen; Body Weight; Butyrates; Cattle; Citrates; Eating; Glucose; Glycogen; Growth Hormone; Hypophysectomy; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Organ Size; Pancreas; Phosphates; Pituitary Gland; Rats; RNA; Serum Albumin; Time Factors; Tolbutamide; Xylitol | 1975 |
Tolbutamide-induced changes of the DNA, protein and insulin content and the secretory activity of isolated rat pancreatic islets.
Topics: Animals; DNA; Glucose; Hyperplasia; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Proteins; Rats; Theophylline; Tolbutamide | 1975 |
Plasma C-peptide and diagnosis of factitious hyperinsulinism. Study of an insulin-dependent diabetic patient with "spontaneous" hypoglycemia.
Topics: Diabetes Mellitus; Diagnosis, Differential; Glucagon; Glucose; Humans; Hyperinsulinism; Hypoglycemia; Insulin; Iodine Radioisotopes; Leucine; Male; Middle Aged; Peptides; Radioimmunoassay; Substance-Related Disorders; Tolbutamide | 1975 |
Endocrinological aspects at follow-up studies in neonatal hypoglycaemia.
Topics: Blood Glucose; Child, Preschool; Fatty Acids, Nonesterified; Follow-Up Studies; Glucose Tolerance Test; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Infant, Newborn; Infant, Newborn, Diseases; Insulin; Leucine; Stimulation, Chemical; Tolbutamide | 1975 |
[Diagnosis of organic hyperinsulinism].
Topics: Diagnosis, Differential; Diazoxide; Fasting; Glucagon; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemia; Leucine; Radiography; Radionuclide Imaging; Tolbutamide | 1975 |
Hypoglycemia and endogenous hyperinsulinism complicating diabetes mellitus. Application of the C-peptide assay to diagnosis and therapy.
Topics: Blood Glucose; Diabetes Complications; Diabetes Mellitus; Growth Hormone; Humans; Hyperinsulinism; Hypoglycemia; Leucine; Male; Middle Aged; Pancreatectomy; Peptides; Tolbutamide | 1975 |
[Hypoglycemia. Series 2: symptoms, diagnosis].
Topics: Adult; Blood Glucose; Catecholamines; Fatigue; Female; Glucagon; Glucose Tolerance Test; Headache; Humans; Hunger; Hypoglycemia; Infant; Infant, Newborn; Insulin; Keto Acids; Leucine; Neurologic Manifestations; Pregnancy; Tolbutamide | 1976 |
Effects of thiamine deficiency on the biosynthesis of insulin in rats.
Topics: Animals; Glucose; Insulin; Leucine; Pancreas; Proinsulin; Rats; Rats, Inbred Strains; Thiamine Deficiency; Tolbutamide | 1991 |
Insulin secretory response to secretagogues by perifused islets from chronically glucose-infused rats.
Topics: Animals; Colforsin; Glucose; In Vitro Techniques; Infusions, Intravenous; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Kinetics; Leucine; Male; Perfusion; Rats; Rats, Mutant Strains; Tetradecanoylphorbol Acetate; Thinness; Tolbutamide | 1991 |
Effects of insulin secretagogues on the secretion of insulin during thiamine deficiency.
Topics: Animals; Arginine; Blood Glucose; Insulin; Insulin Secretion; Leucine; Rats; Rats, Inbred Strains; Thiamine Deficiency; Tolbutamide | 1988 |
Effects of sulphonylureas and diazoxide on insulin secretion and nucleotide-sensitive channels in an insulin-secreting cell line.
Topics: Adenosine Triphosphate; Animals; Cell Line; Diazoxide; Electrophysiology; Glucose; Glyburide; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Nucleotides; Potassium Channels; Rats; Sulfonylurea Compounds; Tolbutamide | 1988 |
Modulation of the effect of acetylcholine on insulin release by the membrane potential of B cells.
Topics: Acetylcholine; Animals; Arginine; Calcium Radioisotopes; Cell Membrane; Diazoxide; Female; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Membrane Potentials; Mice; Potassium; Radioisotopes; Rubidium; Tolbutamide | 1987 |
Regulation by various hormones and agents of adenosine-3',5'-monophosphate levels in islets of Langerhans of rats.
Topics: Adenine; Adrenergic beta-Antagonists; Adrenocorticotropic Hormone; Animals; Cresols; Cyclic AMP; Epinephrine; Glucagon; Glucose; Guanosine Triphosphate; Hormones; In Vitro Techniques; Islets of Langerhans; Isoproterenol; Leucine; Phenformin; Phenoxybenzamine; Phentolamine; Propanolamines; Propranolol; Propylamines; Prostaglandins; Rats; Receptors, Adrenergic; Secretin; Sotalol; Theophylline; Thyrotropin; Tolbutamide; Tritium | 1974 |
The pancreatic -cell recognition of insulin secretagogues. IV. Islet uptake of sulfonylureas.
Topics: Animals; Antimycin A; Carbon Isotopes; Chlorpromazine; Diazoxide; Glucose; Glyburide; In Vitro Techniques; Islets of Langerhans; Leucine; Male; Mice; Serum Albumin; Sulfur Isotopes; Tolbutamide | 1973 |
Interrelationship of islet metabolism, adenosine triphosphate content and insulin release.
Topics: Adenosine Triphosphate; Animals; Carbon Isotopes; Glucose; Glyburide; Glyceraldehyde; Heptoses; Hexoses; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Mice; Models, Biological; Nitriles; Oxidative Phosphorylation; Phenylhydrazines; Time Factors; Tolbutamide; Uncoupling Agents | 1973 |
An inhibitory effect of tolbutamide and glibenclamide (glyburide) on the pancreatic islets of normal animals.
Topics: Animals; Blood Glucose; Carbon Radioisotopes; Female; Glucose; Glyburide; Insulin; Islets of Langerhans; Leucine; Tolbutamide | 1974 |
The bioelectrical properties of pancreatic islet cells: effects of diabetogenic agents.
Topics: Action Potentials; Alloxan; Animals; Anti-Bacterial Agents; Diabetes Mellitus, Experimental; Female; Glucosamine; Glucose; Glutathione; Glyceraldehyde; Heptoses; In Vitro Techniques; Islets of Langerhans; Leucine; Male; Mice; Niacinamide; Nitroso Compounds; Tolbutamide; Urea | 1972 |
[Insuloma; on endocrine function].
Topics: Adenoma, Islet Cell; Humans; Hyperglycemia; In Vitro Techniques; Insulin; Leucine; Tolbutamide | 1965 |
Biochemical studies in a patient with hyperinsulinism.
Topics: Adenoma, Islet Cell; Adult; Female; Glucagon; Glucose Tolerance Test; Humans; Hydrocortisone; Hyperinsulinism; Hypoglycemia; Leucine; Pancreatic Neoplasms; Tolbutamide | 1966 |
Islet cell adenoma in childhood: report of a case.
Topics: Adenoma; Adenoma, Islet Cell; Catecholamines; Child; Electroencephalography; Epinephrine; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Intelligence Tests; Leucine; Male; Tolbutamide | 1967 |
The diagnosis of insuloma.
Topics: Adenoma, Islet Cell; Adult; Aged; Diagnosis, Differential; Fasting; Female; Glucagon; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemia; Leucine; Male; Middle Aged; Radiography; Tolbutamide | 1967 |
Plasma growth hormone levels in spontaneous hypoglycemia.
Topics: Adenoma, Islet Cell; Adrenal Gland Diseases; Adult; Aged; Carcinoma; Cholangitis; Deficiency Diseases; Fasting; Female; Fluorometry; Glucose; Glucose Tolerance Test; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Immunoassay; Insulin; Leucine; Lung Neoplasms; Male; Middle Aged; Pancreatitis; Sertoli-Leydig Cell Tumor; Stomach Neoplasms; Tolbutamide | 1967 |
The tolbutamide tolerance texxt in the evaluation of childhood hypoglycemia.
Topics: Acidosis; Adenoma, Islet Cell; Child; Child, Preschool; Diagnosis, Differential; Humans; Hypoglycemia; Infant; Leucine; Tolbutamide | 1967 |
ACTH-mediated insulin secretion: effect of aminophylline.
Topics: Adenine Nucleotides; Adrenalectomy; Adrenocorticotropic Hormone; Aminophylline; Animals; Blood Glucose; Carbon Isotopes; Glucagon; Glucose; Insulin; Islets of Langerhans; Leucine; Male; Mice; Phosphoric Monoester Hydrolases; Protein Biosynthesis; Tolbutamide | 1967 |
Studies in hypoglycemia of infancy and childhood. Diagnosis and treatment.
Topics: Adenoma, Acidophil; Adolescent; Blood Glucose; Child; Child, Preschool; Diet Therapy; Epinephrine; Female; Glucagon; Glucocorticoids; Glucose Tolerance Test; Humans; Hypoglycemia; Hypopituitarism; Infant; Insulin; Leucine; Male; Pancreatectomy; Tolbutamide | 1967 |
Insulin-secreting islet-cell tumours of the pancreas.
Topics: Adenoma, Islet Cell; Adult; Duodenum; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Pancreatectomy; Pancreatic Neoplasms; Tolbutamide | 1967 |
Insulin secretion by insuloma and normal pancreas slices. Studies in a patient with multiple endocrine adenomata.
Topics: Adenoma; Adenoma, Islet Cell; Adult; Female; Glucose; Glucose Tolerance Test; Humans; In Vitro Techniques; Insulin; Leucine; Mannose; Pancreas; Pancreatectomy; Pancreatic Neoplasms; Parathyroid Neoplasms; Polycystic Kidney Diseases; Tolbutamide | 1968 |
Hypoglycemia in a two-year-old boy with adrenocorticotropic hormone (ACTH) deficiency (probably isolated) and adrenal medullary unresponsiveness to insulin-induced hypoglycemia.
Topics: Adrenal Insufficiency; Adrenal Medulla; Adrenocorticotropic Hormone; Blood Glucose; Catecholamines; Child, Preschool; Epinephrine; Glucose Tolerance Test; Humans; Hypoglycemia; Hypopituitarism; Insulin Coma; Leucine; Male; Norepinephrine; Pituitary-Adrenal Function Tests; Tolbutamide; Transferases | 1968 |
Potassium ions and the secretion of insulin by islets of Langerhans incubated in vitro.
Topics: Animals; Depression, Chemical; Glucose; Immunoassay; In Vitro Techniques; Insulin; Insulin Secretion; Iodine Isotopes; Islets of Langerhans; Leucine; Male; Methods; Microbial Collagenase; Ouabain; Pancreas; Potassium; Potassium Isotopes; Rabbits; Stimulation, Chemical; Tolbutamide; Tritium | 1968 |
[Current methods of study and morphologic findings in B-cell adenoma of the pancreas].
Topics: Adenoma, Islet Cell; Adolescent; Blood Glucose; Diagnosis, Differential; Female; Glucose Tolerance Test; Humans; Hyperinsulinism; Leucine; Microscopy, Electron; Pancreas; Pancreatic Neoplasms; Tolbutamide | 1967 |
Further studies on diazoxide suppression of insulin release from abnormal and normal islet tissue in man.
Topics: Adenoma, Islet Cell; Arginine; Blood Glucose; Catecholamines; Depression, Chemical; Diazoxide; Female; Glucagon; Glucose; Humans; Hyperglycemia; Hyperinsulinism; Hypoglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Tolbutamide; Trichlormethiazide | 1968 |
Glucagon test for insulinoma: a chemical study in 25 cases.
Topics: Adenoma, Islet Cell; Adult; Blood Glucose; Diagnosis, Differential; Female; Glucagon; Humans; Hyperinsulinism; Hypoglycemia; Insulin; Leucine; Male; Middle Aged; Tolbutamide | 1968 |
[Apropos of a case of severe hypoglycemia. Present possibilities of diagnosis and treatment].
Topics: Adenoma, Islet Cell; Blood Glucose; Diagnosis, Differential; Diazoxide; Glucocorticoids; Glucose; Glucose Tolerance Test; Humans; Hypoglycemia; Infant; Insulin; Leucine; Male; Pancreatectomy; Tolbutamide | 1968 |
Islet cell tumors and hypoglycemia.
Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Child; Fasting; Female; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Infant; Infant, Newborn; Insulin; Insulin Secretion; Leucine; Male; Middle Aged; Radiography; Tolbutamide | 1969 |
Idiopathic hypoglycemia: a study of twenty-six children.
Topics: Adrenocorticotropic Hormone; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Diabetes Mellitus; Diet Therapy; Electroencephalography; Female; Glucose Tolerance Test; Humans; Hypoglycemia; Infant; Infant, Newborn; Infant, Newborn, Diseases; Insulin; Insulin Secretion; Intellectual Disability; Leucine; Liver Glycogen; Male; Neurologic Manifestations; Pancreatectomy; Prednisone; Pregnancy; Tolbutamide | 1969 |
Islet cell tumors of the pancreas.
Topics: Adenoma, Islet Cell; Aged; Fasting; Female; Humans; Hypoglycemia; Insulin; Leucine; Male; Middle Aged; Pancreatic Neoplasms; Tolbutamide | 1969 |
Plasma insulin studies in the diagnosis of insulinoma.
Topics: Adenoma, Islet Cell; Adult; Aged; Blood Glucose; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Leucine; Male; Middle Aged; Pancreatic Neoplasms; Tolbutamide | 1969 |
[Alcoholic hypoglycemia in adults].
Topics: Adult; Alcoholism; Diet; Glucagon; Glucose Tolerance Test; Hepatic Encephalopathy; Humans; Hypoglycemia; Insulin; Leucine; NAD; Socioeconomic Factors; Tolbutamide | 1968 |
Insulin stimulatory tests in a patient with islet cell adenoma.
Topics: Adenoma, Islet Cell; Aged; Antigen-Antibody Reactions; Blood Glucose; Fasting; Female; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Insulin Antibodies; Insulin Secretion; Leucine; Methods; Tolbutamide | 1969 |
Planning the appropriate operations for islet cell tumors of the pancreas.
Topics: Adenoma, Islet Cell; Angiography; Blood Glucose; Glucose Tolerance Test; Humans; Leucine; Neoplasm Metastasis; Pancreatic Neoplasms; Radionuclide Imaging; Tolbutamide | 1970 |
Medical grand rounds at Yale-New Haven Hospital. Diagnosis and management of hypoglycemia.
Topics: Adenoma, Islet Cell; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Leucine; Pancreatic Neoplasms; Tolbutamide | 1970 |
Islet cell tumor with hypoglycemia.
Topics: Adenoma, Islet Cell; Adolescent; Adult; Female; Glucagon; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemia; Insulin; Leucine; Middle Aged; Pancreatectomy; Pancreatic Neoplasms; Radioimmunoassay; Tolbutamide | 1971 |
[2 cases of Langerhans adenoma].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma, Islet Cell; Adult; Aged; Angiography; Celiac Artery; Female; Gastrointestinal Hemorrhage; Glucagon; Humans; Hypoglycemia; Insulin; Intracranial Arteriosclerosis; Leucine; Mesenteric Arteries; Obesity; Pancreatectomy; Pancreatic Neoplasms; Pregnancy; Pregnancy Complications; Prognosis; Tolbutamide | 1969 |
Islet cell adenomatosis and adenoma in an infant.
Topics: Adenoma, Islet Cell; Adrenocorticotropic Hormone; Diazoxide; Glucose; Humans; Hypoglycemia; Infant, Newborn; Infant, Newborn, Diseases; Intellectual Disability; Leucine; Male; Pancreatectomy; Pancreatic Neoplasms; Prednisone; Tolbutamide | 1971 |
Proinsulin-like component of circulating insulin in the basal state and in patients and hamsters with islet cell tumors.
Topics: Acromegaly; Adenoma, Islet Cell; Adolescent; Adult; Animals; Child; Chromatography, Gel; Cricetinae; Cushing Syndrome; Diazoxide; Disease Models, Animal; Female; Glucagon; Glucose Tolerance Test; Half-Life; Humans; Hypoglycemia; Hypokalemia; Insulin; Iodine Isotopes; Leucine; Male; Middle Aged; Myotonic Dystrophy; Neoplasms, Experimental; Obesity; Proinsulin; Radioimmunoassay; Stimulation, Chemical; Tolbutamide | 1971 |
Insulin release from human fetal pancreas in vitro.
Topics: Arginine; Barium; Body Weight; Cyclic AMP; Female; Fetus; Gestational Age; Glucagon; Glucose; Humans; In Vitro Techniques; Insulin; Insulin Secretion; Leucine; Ouabain; Pancreas; Potassium; Pregnancy; Theophylline; Tolbutamide | 1971 |
Activation of adenyl cyclase in a pancreatic islet cell adenoma by glucagon and tolbutamide.
Topics: Adenoma, Islet Cell; Adenosine Triphosphate; Adenylyl Cyclases; Administration, Oral; Arginine; Blood Glucose; Cyclic AMP; Enzyme Activation; Fasting; Fluorides; Glucagon; Glucose; Humans; Hypoglycemia; In Vitro Techniques; Injections, Intravenous; Insulin; Insulin Secretion; Leucine; Male; Middle Aged; Phosphorus Isotopes; Tolbutamide | 1972 |
Insulin and glucose patterns in control subjects and in proved insulinoma.
Topics: Adenoma, Islet Cell; Adult; Aged; Blood Glucose; Child; False Negative Reactions; Fasting; Female; Glucagon; Humans; Hypoglycemia; Insulin; Leucine; Male; Middle Aged; Pancreatic Neoplasms; Time Factors; Tolbutamide | 1971 |
Beta cell adenoma in a child with hypoglycemia controlled with diazoxide.
Topics: Adenoma, Islet Cell; Blood Glucose; Child, Preschool; Diazoxide; Female; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Leucine; Microscopy, Electron; Pancreatectomy; Pancreatic Neoplasms; Splenectomy; Tolbutamide | 1972 |
Diphenylhydantoin and an insulin-secreting islet adenoma.
Topics: Adenoma, Islet Cell; Adult; Blood Glucose; Epilepsy, Tonic-Clonic; Glucagon; Humans; Insulin; Insulin Secretion; Leucine; Male; Nitrogen; Pancreas; Phenytoin; Tolbutamide | 1972 |
Insulinoma diagnosed by insulin immunoassay and angiography.
Topics: Adenoma, Islet Cell; Angiography; Blood Glucose; Child; Humans; Hypoglycemia; Immunoassay; Insulin; Leucine; Male; Pancreatic Neoplasms; Proinsulin; Tolbutamide | 1972 |
Various tests in the evaluation of islet cell adenomas.
Topics: Adenoma, Islet Cell; Blood Glucose; Fasting; Glucagon; Humans; Insulin; Leucine; Male; Middle Aged; Pancreatic Neoplasms; Proinsulin; Tolbutamide | 1973 |
[Comparative evaluation of the tolbutamide and leucine tests in insulinoma].
Topics: Adenoma, Islet Cell; Adolescent; Adult; Female; Humans; Leucine; Male; Middle Aged; Tolbutamide | 1972 |
The mode of action of adenosine 3':5'-cyclic monophosphate in mammalian islets of Langerhans. Effects of insulin secretagogues on islet-cell protein kinase activity.
Topics: Animals; Arginine; Caffeine; Cyclic AMP; Diazoxide; Epinephrine; Glucagon; Glyburide; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Phosphorus Isotopes; Phosphotransferases; Protein Kinases; Rats; Theophylline; Time Factors; Tolbutamide; Xanthines; Xylitol | 1973 |
[Functioning beta-insular tumors of the pancreas. Principal diagnostic tests].
Topics: Adenoma, Islet Cell; Aortography; Blood Glucose; Fasting; Glucose Tolerance Test; Humans; Leucine; Methods; Pancreatic Neoplasms; Radionuclide Imaging; Tolbutamide | 1973 |
Current concepts in diagnosis of insulinoma.
Topics: Adenoma, Islet Cell; Blood Glucose; Fasting; Glucagon; Humans; Hypoglycemia; Insulin; Leucine; Proinsulin; Tolbutamide | 1974 |
[Exploration of hypoglycemia].
Topics: Adenoma, Islet Cell; Arginine; Blood Glucose; Diazoxide; Diet; Fasting; Glucagon; Hormones, Ectopic; Humans; Hypoglycemia; Insulin; Insulin Secretion; Leucine; Medical History Taking; Pancreatic Neoplasms; Physical Examination; Time Factors; Tolbutamide | 1974 |
[Atypical case of insulinoma (author's transl)].
Topics: Adenoma, Islet Cell; Angiography; Blood Glucose; Fasting; Female; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Leucine; Middle Aged; Pancreatic Neoplasms; Tolbutamide; Ultrasonography | 1974 |
The diagnostic evaluation of the patient with hypoglycemic symptoms.
Topics: Adrenal Glands; Diagnosis, Differential; Fasting; Glucose Tolerance Test; Humans; Hyperventilation; Hypoglycemia; Hypotension; Leucine; Pheochromocytoma; Radiography; Sella Turcica; Thyroid Gland; Tolbutamide | 1972 |
Islet cell function and glucose homeostasis in hypopituitary dwarfism: synergism between growth hormone and cortisone.
Topics: Blood Glucose; Child; Cortisone; Drug Synergism; Dwarfism, Pituitary; Female; Glucose; Glucose Tolerance Test; Growth Hormone; Homeostasis; Humans; Hypoglycemia; Insulin; Islets of Langerhans; Leucine; Male; Pregnancy; Tolbutamide | 1973 |
Enzyme-induced modifications of beta cell function. I. Effect of pronase on insulin secretion.
Topics: Animals; Cell Membrane; Glucose; Guinea Pigs; Insulin; Insulin Secretion; Iodine Radioisotopes; Islets of Langerhans; Leucine; Male; Perfusion; Pronase; Rabbits; Rats; Swine; Tolbutamide | 1974 |
The effect of tolbutamide and glibenclamide on the incorporation of ( 3 H)leucine and on the conversion of proinsulin to insulin in isolated pancreatic islets.
Topics: Animals; Chromatography, Gel; Depression, Chemical; Glucose; Glyburide; Insulin; Insulin Secretion; Islets of Langerhans; Isotope Labeling; Leucine; Male; Mice; Proinsulin; Rats; Time Factors; Tolbutamide; Tritium | 1972 |
[The effect of oral antidiabetics on the biosynthesis of proinsulin in the rat].
Topics: Animals; Chromatography, Gel; Electrophoresis, Disc; Glucose; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Islets of Langerhans; Leucine; Male; Proinsulin; Pyrimidines; Rats; Sulfonic Acids; Sulfonylurea Compounds; Tolbutamide; Tritium | 1972 |
Metabolic aspects of the Beckwith-Wiedemann syndrome.
Topics: Abnormalities, Multiple; Adrenal Gland Diseases; Blood Glucose; Child, Preschool; Diazoxide; Epinephrine; Glucagon; Glucose; Glucose Tolerance Test; Growth Hormone; Hernia, Umbilical; Humans; Hydrocortisone; Hyperinsulinism; Hypoglycemia; Infant, Newborn; Infant, Newborn, Diseases; Insulin; Kidney Diseases; Leucine; Male; Tolbutamide; Tongue; Umbilicus | 1973 |
Glucose, tolbutamide and leucine tolerances in hypoglycemia.
Topics: Administration, Oral; Blood Glucose; Diabetes Complications; Diabetes Mellitus; Glucose Tolerance Test; Humans; Hypoglycemia; Injections, Intravenous; Insulin; Leucine; Time Factors; Tolbutamide | 1973 |
Incorporation of leucine into protein by isolated fat cells--effects of agents which stimulate glucose metabolism and inhibit lipolysis.
Topics: Adenine Nucleotides; Adipose Tissue; Animals; Concanavalin A; Cysteine; Glucose; In Vitro Techniques; Insulin; Leucine; Lipid Metabolism; Nystatin; Ouabain; Polyamines; Propylamines; Protein Biosynthesis; Pyruvates; Rats; Spermidine; Swine; Tolbutamide; Tritium; Vitamin K | 1973 |
[Hypoglycemia].
Topics: Child; Dietary Carbohydrates; Epinephrine; Gastrointestinal Hormones; Glucagon; Gluconeogenesis; Glucose; Humans; Hyperglycemia; Hyperinsulinism; Hypoglycemia; Hypoglycemic Agents; Insulin; Intestinal Absorption; Leucine; Liver Glycogen; Pancreatic Neoplasms; Thyroid Hormones; Tolbutamide | 1973 |
Perifusion of pancreas fragments. A system for the study of dynamic aspects of insulin secretion.
Topics: Alanine; Animals; Arginine; Culture Media; Fructose; Galactose; Glucose; Glycolysis; Hydrogen-Ion Concentration; In Vitro Techniques; Insulin; Insulin Antibodies; Insulin Secretion; Iodine Radioisotopes; Leucine; Male; Mannose; Methods; Pancreas; Perfusion; Rats; Ribose; Time Factors; Tolbutamide; Xylitol | 1974 |
Plasma insulin in patients with myotonic dystrophy and their relatives.
Topics: Adolescent; Adult; Aged; Amino Acids; Antigens; Arginine; Child; Child, Preschool; Electromyography; Female; Glucagon; Glucose Tolerance Test; Heterozygote; Humans; Hyperinsulinism; Insulin; Leucine; Male; Middle Aged; Muscles; Myotonic Dystrophy; Tolbutamide | 1974 |
Dynamics of insulin secretion in myotonic dystrophy.
Topics: Adult; Blood Glucose; Epinephrine; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Middle Aged; Myotonic Dystrophy; Tolbutamide | 1968 |
Electrical activity in pancreatic islet cells.
Topics: Action Potentials; Animals; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Membrane Potentials; Mice; Tolbutamide | 1968 |
Effects of amino acids on insulin release from excised rabbit pancreas.
Topics: Amino Acids; Animals; Arginine; Epinephrine; Glucose; Histidine; In Vitro Techniques; Insulin; Insulin Antagonists; Insulin Secretion; Islets of Langerhans; Leucine; Lysine; Rabbits; Stimulation, Chemical; Tolbutamide | 1969 |
A-cell deficiency and B-cell hyperplasia of Langerhans' islet as a cause of leucine sensitive hypoglycemia.
Topics: Blood Glucose; Diazoxide; Epinephrine; Glucose Tolerance Test; Humans; Hyperplasia; Hypoglycemia; Infant; Insulin; Islets of Langerhans; Leucine; Male; Pancreatectomy; Pancreatic Diseases; Seizures; Tolbutamide | 1968 |
[Effect of blood sugar decreasing sulfonylureas on the in vitro metabolism of glucose and amino acids in the beta-cells of the pancreas in mice].
Topics: Alanine; Amino Acids; Animals; Arginine; Carbon Isotopes; Depression, Chemical; Female; Glucose; Hyperglycemia; Hypoglycemic Agents; In Vitro Techniques; Insulin; Islets of Langerhans; Leucine; Male; Mice; Obesity; Oxidation-Reduction; Oxygen Consumption; Pancreas; Stimulation, Chemical; Tolbutamide; Urea; Valine | 1969 |
Insulin biosynthesis: effects of carbohydrates and related compounds.
Topics: Animals; Fructose; Fumarates; Globulins; Glucose; Glutamates; Hexoses; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Mannose; Protein Binding; Pyruvates; Rats; Ribose; Tolbutamide; Tritium; Xylitol | 1969 |
The role of calcium and magnesium in insulin secretion from rabbit pancreas studied in vitro.
Topics: Animals; Calcium; Culture Media; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Magnesium; Rabbits; Tolbutamide | 1967 |
[Regulation of insulin release in perifused pancreatic tissue].
Topics: Amino Acids; Animals; Aprotinin; Arginine; Freezing; Glucagon; Glucose; Hypoglycemic Agents; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Pancreas; Perfusion; Rats; Sulfonamides; Tolbutamide | 1969 |
The pancreatic islet of infants with severe hypoglycemia.
Topics: Blood Glucose; Epinephrine; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Glucose Tolerance Test; Growth Hormone; Humans; Hyperplasia; Hypertrophy; Hypoglycemia; Infant; Infant, Newborn; Insulin; Islets of Langerhans; Leucine; Microscopy, Electron; Radioimmunoassay; Time Factors; Tolbutamide | 1970 |
The effect of glucose on insulin biosynthesis by isolated islets of Langerhans of the rat.
Topics: Animals; Ascites; Carbon Isotopes; Chromatography, Gel; Cycloheximide; Electrophoresis; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Liver; Male; Metabolism; Mice; Phenylalanine; Protein Biosynthesis; Tolbutamide | 1970 |
In vitro effect of various hypoglycemic agents on the hepatic and pancreatic protein synthesis in the rat.
Topics: Animals; Cell-Free System; Depression, Chemical; Ethers; Female; Glyburide; Hypoglycemic Agents; Leucine; Liver; Male; Metabolism; Pancreas; Protein Biosynthesis; Pyrimidines; Rats; Rats, Inbred Strains; Sulfonylurea Compounds; Terpenes; Tolbutamide; Tritium | 1971 |
Hypoglycemic action of 2-aminonorbornane-2-carboxylic acid in the rat.
Topics: Amino Acids; Amino Acids, Cyclic; Animals; Binding Sites; Blood Glucose; Drug Synergism; Hypoglycemia; Insulin; Insulin Secretion; Kinetics; Leucine; Male; Rats; Stereoisomerism; Structure-Activity Relationship; Terpenes; Tolbutamide | 1971 |
Failure of leucine, arginine, and epinephrine to alter plasma insulin levels in vitro.
Topics: Animals; Antigen-Antibody Reactions; Arginine; Depression, Chemical; Epinephrine; Guinea Pigs; Humans; Insulin; Insulin Antibodies; Iodine Isotopes; Leucine; Radioimmunoassay; Stimulation, Chemical; Swine; Tolbutamide | 1971 |
Study on the formation and release of insulin with special reference to electron microscopic observation.
Topics: Animals; Blood Glucose; Female; Glucose; Insulin; Insulin Antibodies; Islets of Langerhans; Leucine; Male; Microscopy, Electron; Rabbits; Tolbutamide | 1966 |
[The effect of L-leucine on blood sugar and serum phosphate in rabbits].
Topics: Animals; Blood Glucose; Carbutamide; Fasting; Female; Injections, Intravenous; Insulin; Leucine; Male; Phosphates; Rabbits; Tolbutamide | 1969 |
Studies in spiny mice (Acomys cahirinus): metabolic state and pancreatic insulin release in vitro.
Topics: Age Factors; Animals; Antigens; Arginine; Blood Glucose; Caffeine; Calcium; Diabetes Mellitus; Glucagon; Glycosuria; Hyperglycemia; In Vitro Techniques; Insulin; Insulin Secretion; Leucine; Mice; Mice, Inbred Strains; Obesity; Pancreas; Tolbutamide | 1969 |
Studies on the radioimmunological determination of blood insulin by means of 125-I-insulin of high specific activity.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Animals; Blood Glucose; Diabetes Mellitus, Type 1; Fasting; Female; Glucagon; Glucose; Humans; Infant; Insulin; Iodine Isotopes; Leucine; Methods; Obesity; Radioimmunoassay; Swine; Tolbutamide | 1970 |
The effects of epinephrine, amino acids and albumin on the measurement of insulin by radioimmunoassay.
Topics: Animals; Antigen-Antibody Reactions; Antigens; Arginine; Binding Sites; Chemical Phenomena; Chemistry; Diazoxide; Epinephrine; Evaluation Studies as Topic; Glucose; Glucose Tolerance Test; Guinea Pigs; Humans; Immune Sera; Insulin; Insulin Antibodies; Iodine Isotopes; Leucine; Methods; Protein Binding; Radioimmunoassay; Serum Albumin; Swine; Tolbutamide | 1970 |
[Diagnostic tests in hypoglycemic syndromes].
Topics: Blood Glucose; Diagnosis, Differential; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Leucine; Tolbutamide | 1970 |
Insulin secretion studied in the perfused rat pancreas. I. Effect of tolbutamide, leucine and arginine; their interaction with diazoxide, and relation to glucose.
Topics: Animals; Arginine; Buffers; Diazoxide; Glucose; Insulin; Insulin Secretion; Leucine; Male; Pancreas; Perfusion; Radioimmunoassay; Rats; Stimulation, Chemical; Tolbutamide | 1971 |
[Cerebral convulsion as symptom in spontaneous hypoglycemia in childhood].
Topics: Acetone; Adrenal Cortex Hormones; Blood Glucose; Child, Preschool; Diagnosis, Differential; Diet Therapy; Dietary Fats; Electroencephalography; Epinephrine; Female; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Infant; Insulin; Leucine; Male; Prognosis; Seizures; Tolbutamide | 1971 |
[Management of functional hypoglycemia in the adult].
Topics: Adult; Fructose; Galactosemias; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Leucine; Tolbutamide | 1967 |
[Functional exploration of insulin secretion in sponteaneous hypoglycemia].
Topics: Adenoma; Arginine; Glucagon; Glucose; Humans; Hyperinsulinism; Hypoglycemia; Insulin; Insulin Secretion; Leucine; Pancreas; Pancreatic Neoplasms; Tolbutamide | 1967 |
Tolbutamide and the incorporation of [3H]leucine into insulin in vitro.
Topics: Animals; Humans; In Vitro Techniques; Insulin; Leucine; Pancreas; Rabbits; Secretory Rate; Tolbutamide; Tritium | 1967 |
The role of sodium and potassium in insulin secretion from rabbit pancreas.
Topics: Animals; Atropine; Biological Transport, Active; Choline; Glucagon; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Leucine; Lithium; Ouabain; Pancreas; Potassium; Rabbits; Sodium; Tolbutamide | 1968 |
Effect of in vivo administration of various oral hypoglycemic agents on hepatic protein synthesis.
Topics: Animals; Carbon Isotopes; Female; Leucine; Liver; Microsomes; Phenformin; Protein Biosynthesis; Rats; Tolbutamide | 1968 |
Tolbutamide tolerance test and plasma-insulin response in hypoglycemia.
Topics: Amino Acid Metabolism, Inborn Errors; Blood Glucose; Child; Diagnosis, Differential; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Leucine; Tolbutamide | 1968 |
Response of hepatic alpha-glycerophosphate to changes in hepatic glucose formation.
Topics: Animals; Blood Glucose; Dogs; Fasting; Glucose; Glycerophosphates; Glycolysis; Leucine; Liver; Liver Extracts; Male; Rats; Tolbutamide | 1968 |
The inhibition in vitro of hepatic protein biosynthesis by various oral hypoglycemic agents--site of action.
Topics: Animals; Carbon Isotopes; Chlorpropamide; Female; Hypoglycemic Agents; In Vitro Techniques; Leucine; Liver; Lysine; Microsomes; Phenformin; Phenylalanine; Protein Biosynthesis; Rats; RNA, Transfer; Time Factors; Tolbutamide | 1969 |
Behavior in the rat of a transport-specific, bicyclic amino acid. Hypoglycemic action.
Topics: Adrenal Glands; Adrenalectomy; Amino Acids; Animals; Blood Glucose; Bridged-Ring Compounds; Carbon Isotopes; Diaphragm; Drug Synergism; Leucine; Male; Pancreas; Phenylalanine; Rats; Stereoisomerism; Tolbutamide | 1969 |
Diazoxide in the management of hypoglycemia in infancy and childhood.
Topics: Blood Glucose; Child; Child, Preschool; Diazoxide; Female; Glucose; Glucose Tolerance Test; Growth Hormone; Humans; Hypoglycemia; Infant; Insulin; Insulin Secretion; Leucine; Male; Tolbutamide | 1969 |
The response of infants of diabetic women to tolbutamide and leucine at birth, and to glucose and tolbutamide at 2 years of age.
Topics: Blood Glucose; Child, Preschool; Diabetes Mellitus; Female; Glucose Tolerance Test; Humans; Infant, Newborn; Injections, Intravenous; Insulin; Insulin Secretion; Leucine; Male; Prediabetic State; Pregnancy; Pregnancy in Diabetics; Tolbutamide | 1969 |
[Idiopathic hypoglycemia in the child].
Topics: Age Factors; Child; Child, Preschool; Epinephrine; Fatty Acids, Nonesterified; Female; Glucagon; Glucose Tolerance Test; Growth Hormone; Humans; Hypoglycemia; Infant; Infant, Newborn; Insulin; Leucine; Male; Tolbutamide | 1969 |
The interaction of various inhibitors and stimuli of insulin release studied with rabbit pancreas in vitro.
Topics: Animals; Barium; Diazoxide; Dibucaine; Dinitrophenols; Epinephrine; Glucose; Heptoses; Hypoxia; In Vitro Techniques; Insulin; Insulin Secretion; Leucine; Ouabain; Pancreas; Potassium; Rabbits; Tetrodotoxin; Tolbutamide | 1969 |
Spontaneous hypoglycaemia and sarcoma. A case report.
Topics: Blood; Fibrosarcoma; Glucagon; Glucose Tolerance Test; Granulosa Cell Tumor; Humans; Hypoglycemia; Insulin; Leucine; Male; Middle Aged; Tolbutamide | 1965 |
L-leucine in secondary sulfonylurea failure.
Topics: Aged; Chlorpropamide; Diabetes Mellitus; Female; Humans; In Vitro Techniques; Leucine; Male; Middle Aged; Tolbutamide | 1966 |
Hypoglycemia due to intrapancreatic infusion of leucine.
Topics: Animals; Dogs; Hypoglycemia; Insulin; Leucine; Liver; Pancreas; Tolbutamide | 1966 |
The in vitro effect of two oral hypoglycemic agents on hepatic protein synthesis.
Topics: Animals; Biguanides; Carbon Dioxide; Glucose; Hypoglycemic Agents; In Vitro Techniques; Leucine; Liver; Protein Biosynthesis; Rats; Tolbutamide | 1966 |
Effect of insulin, chlorpropamide and tolbutamide on the metabolism of branched chain amino acids.
Topics: Animals; Chlorpropamide; In Vitro Techniques; Insulin; Isoleucine; Leucine; Rabbits; Rats; Tolbutamide; Valine | 1966 |
Cortisol production rate. VI. Hypoglycemia in the neonatal and postneonatal period, and in association with dwarfism.
Topics: 17-Ketosteroids; Birth Weight; Child; Child, Preschool; Dwarfism; Epinephrine; Female; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Infant; Infant, Newborn; Insulin; Leucine; Male; Pituitary Function Tests; Tolbutamide | 1967 |
Clinical alcohol hypoglycemia.
Topics: Aged; Alcoholic Intoxication; Alcoholism; Blood Glucose; Ethanol; Fasting; Female; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Injections, Intravenous; Leucine; Male; Tolbutamide | 1967 |
Secondary failure to sulphonylureas in the treatment of diabetes.
Topics: Carbutamide; Chlorpropamide; Diabetes Mellitus; Drug Tolerance; Humans; Leucine; Tolbutamide | 1967 |
The effects of three oral hypoglycemic agents on the incorporation of leucine-C14 into protein by liver microsomes of normal and alloxan-diabetic rats.
Topics: Animals; Biguanides; Carbon Isotopes; Chlorpropamide; Diabetes Mellitus, Experimental; Female; Leucine; Liver; Microsomes; Proteins; Rats; Tolbutamide | 1967 |
Metabolic effects of hypoglycemic sulfonylureas. I. In vitro effect of sulfonylureas on leucine incorporation and metabolism and on respiration of rat tissues.
Topics: Adipose Tissue; Animals; Carbon Isotopes; Carbutamide; Chlorpropamide; Diaphragm; Hypoglycemic Agents; In Vitro Techniques; Kidney; Leucine; Liver; Male; Muscle Proteins; Muscles; Oxygen Consumption; Protein Biosynthesis; Rats; Tolbutamide | 1967 |
Evidence that glucose "marks" beta cells resulting in preferential release of newly synthesized insulin.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Leucine; Potassium; Tolbutamide | 1982 |
Thiol-dependent and non-thiol-dependent stimulations of insulin release.
Topics: Animals; Bucladesine; Calcimycin; Calcium; Diamide; Dose-Response Relationship, Drug; Female; Glucose; Glutathione; Glyburide; Glyceraldehyde; Insulin; Insulin Secretion; Islets of Langerhans; Isoproterenol; Leucine; Male; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Tolbutamide | 1984 |
Chloride modulation of insulin release, 86Rb+ efflux, and 45Ca2+ fluxes in rat islets stimulated by various secretagogues.
Topics: Animals; Arginine; Calcium; Chlorides; Exocytosis; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Rats; Rats, Inbred Strains; Rubidium; Theophylline; Tolbutamide | 1983 |
Glucose insensitivity and amino-acid hypersensitivity of insulin release in rats with non-insulin-dependent diabetes. A study with the perfused pancreas.
Topics: Acetylcholine; Amino Acids; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Glucose; Glyceraldehyde; Insulin; Insulin Secretion; Islets of Langerhans; Isoproterenol; Keto Acids; Leucine; Mannose; Rats; Rats, Inbred Strains; Theophylline; Tolbutamide | 1983 |
Effects of D-mannoheptulose on blood glucose and alloxan sensitivity in mice.
Topics: Alloxan; Animals; B-Lymphocytes; Blood Glucose; Diabetes Mellitus, Experimental; Female; Heptoses; Hydroxymercuribenzoates; Insulin; Leucine; Liver Glycogen; Male; Mannoheptulose; Mice; Mice, Inbred C57BL; Starvation; Tolbutamide | 1980 |
cAMP-enhancing agents "permit" stimulus-secretion coupling in canine pancreatic islet beta-cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Membrane; Colforsin; Cyclic AMP; Dogs; Exocytosis; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Membrane Potentials; Thionucleotides; Tolbutamide | 1994 |
Alterations of insulin response to different beta cell secretagogues and pancreatic vascular resistance induced by N omega-nitro-L-arginine methyl ester.
Topics: Analysis of Variance; Animals; Arginine; Drug Interactions; Glucose; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Pancreas; Potassium Chloride; Rats; Rats, Wistar; Stereoisomerism; Tolbutamide; Vascular Resistance; Vasoconstriction; Vasodilator Agents | 1995 |
Secretagogue-induced [Ca2+]i changes in single rat pancreatic islets and correlation with simultaneously measured insulin release.
Topics: Animals; Calcium; Carbachol; Cells, Cultured; Cytosol; Diazoxide; Fluorescent Dyes; Fura-2; Glucose; Glutamine; Indoles; Inulin; Islets of Langerhans; Kinetics; Leucine; Male; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Time Factors; Tolbutamide | 1995 |
The role of the CYP2C9-Leu359 allelic variant in the tolbutamide polymorphism.
Topics: Alleles; Aryl Hydrocarbon Hydroxylases; Asian People; Black People; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Heterozygote; Homozygote; Humans; Leucine; Recombinant Proteins; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Tolbutamide; White People | 1996 |
Optimization of culture conditions for the preservation of monkey pancreatic islets in culture.
Topics: Animals; Arginine; Cell Culture Techniques; Cell Separation; Cell Survival; Cells, Cultured; Female; Glucose; Insulin; Islets of Langerhans; Leucine; Macaca radiata; Male; Tolbutamide | 1999 |
Amyloid fibril formation is progressive and correlates with beta-cell secretion in transgenic mouse isolated islets.
Topics: Amyloid; Animals; Cell Survival; Cells, Cultured; Culture Media, Conditioned; Dose-Response Relationship, Drug; Extracellular Space; Female; Glucose; Glutamine; Humans; Hypoglycemic Agents; Insulin; Islet Amyloid Polypeptide; Islets of Langerhans; Keto Acids; Leucine; Male; Mice; Mice, Transgenic; Time Factors; Tolbutamide | 1999 |
Leucine prolongation of tolbutamide-induced hypoglycemia.
Topics: Humans; Hypoglycemia; Hypoglycemic Agents; Leucine; Pancreatic Diseases; Phosphates; Potassium; Tolbutamide | 1962 |
Acute tolbutamide and leucine effects in diabetes mellitus.
Topics: Diabetes Mellitus; Hyperglycemia; Hypoglycemia; Leucine; Pancreatic Diseases; Phosphates; Potassium; Tolbutamide | 1962 |
FUNCTIONING PANCREATIC ISLET CELL ADENOMA. WITH LEUCINE-INDUCED HYPOGLYCEMIA.
Topics: Adenoma, Islet Cell; Fasting; Humans; Hypoglycemia; Insulin; Leucine; Pancreatic Neoplasms; Pathology; Surgical Procedures, Operative; Tolbutamide; Toxicology | 1963 |
STUDIES ON THE MECHANISM OF LEUCINE-INDUCED HYPOGLYCEMIA.
Topics: Carbohydrate Metabolism; Diaphragm; Fasting; Glucagon; Glycogen; Hypoglycemia; Insulin; Islets of Langerhans; Leucine; Liver Glycogen; Muscles; Pharmacology; Rats; Research; Tolbutamide | 1963 |
THE EFFECT OF ANABOLIC STEROIDS ON BLOOD SUGAR AND PLASMA INSULIN LEVELS IN MAN.
Topics: Adolescent; Anabolic Agents; Blood Chemical Analysis; Blood Glucose; Diabetes Mellitus; Geriatrics; Insulin; Leucine; Nandrolone; Pharmacology; Steroids; Tolbutamide | 1963 |
HYPOGLYCEMIA, GROWTH RETARDATION, AND PROBABLE ISOLATED GROWTH HORMONE DEFICIENCY IN A 1-YEAR-OLD CHILD.
Topics: Carbohydrate Metabolism; Child; Deficiency Diseases; Dwarfism, Pituitary; Growth; Growth Hormone; Human Growth Hormone; Humans; Hypoglycemia; Infant; Leucine; Tolbutamide | 1963 |
EXTRAPANCREATIC INSULIN-SECRETING TUMOR.
Topics: Fibrosarcoma; Geriatrics; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Leucine; Pathology; Retroperitoneal Neoplasms; Surgical Procedures, Operative; Tolbutamide | 1964 |
STUDIES OF CARBOHYDRATE METABOLISM IN THE NEWBORN INFANT. VII. TESTS OF CARBOHYDRATE TOLERANCE IN PREMATURE INFANTS.
Topics: Blood Glucose; Carbohydrate Metabolism; Drug Tolerance; Epinephrine; Fructose; Galactose; Glucagon; Glucose Tolerance Test; Humans; Infant; Infant, Newborn; Infant, Premature; Leucine; Tolbutamide | 1963 |
LEUCINE-INDUCED HYPOGLYCAEMIA AND ORAL HYPOGLYCAEMIC DRUGS.
Topics: Autoradiography; Carbon Isotopes; Chromatography; Diaphragm; Hypoglycemia; Hypoglycemic Agents; Insulin; Leucine; Pharmacology; Phenformin; Proteins; Rats; Research; Tolbutamide | 1964 |
[HYPOGLYCEMIC REACTION TO LEUCINE, VALINE AND PHENYLALANINE IN A CASE OF DIFFUSE HYPERPLASIA OF THE BETA CELLS].
Topics: Glucose Tolerance Test; Humans; Hyperinsulinism; Hyperplasia; Hypoglycemia; Hypoglycemic Agents; Insulin-Secreting Cells; Islands; Islets of Langerhans; Leucine; Pathology; Pharmacology; Phenylalanine; Tolbutamide; Valine | 1963 |
LEUCINE-SENSITIVE HYPOGLYCEMIA.
Topics: Glucose Tolerance Test; Humans; Hypoglycemia; Infant; Leucine; Metabolism; Methylprednisolone; Seizures; Tolbutamide | 1964 |
SYMPTOMATIC NEONATAL HYPOGLYCEMIA. STUDIES OF CARBOHYDRATE METABOLISM IN THE NEWBORN INFANT. VIII.
Topics: Adolescent; Black People; Blood Chemical Analysis; Carbohydrate Metabolism; Central Nervous System Diseases; Child; Diseases in Twins; Epinephrine; Female; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Infant; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature, Diseases; Leucine; Liver Glycogen; Neurologic Manifestations; Polycythemia; Pre-Eclampsia; Pregnancy; Tolbutamide | 1964 |
FUNCTIONING ISLET CELL ADENOMA.
Topics: Adenoma, Islet Cell; Cerebrovascular Disorders; Diagnosis, Differential; Geriatrics; Humans; Hyperinsulinism; Leucine; Pancreatic Neoplasms; Tolbutamide | 1964 |
SPONTANEOUS HYPOGLYCEMIA: DIAGNOSTIC CONSIDERATIONS AND MANAGEMENT.
Topics: Adenoma, Islet Cell; Diabetes Mellitus; Diagnosis, Differential; Humans; Hypoglycemia; Leucine; Malingering; Neoplasm Metastasis; Pancreatic Neoplasms; Surgical Procedures, Operative; Tolbutamide | 1964 |
[STUDIES ON ORAL TOLBUTAMIDE TEST].
Topics: Blood Glucose; Carbutamide; Cystine; Diabetes Mellitus; Diagnosis; Gastric Juice; Hypoglycemia; Leucine; Liver Cirrhosis; Nephritis; Pancreatic Diseases; Pharmacology; Tolbutamide | 1964 |
PLASMA INSULIN IN ORGANIC HYPERINSULINISM: COMPARATIVE EFFECTS OF TOLBUTAMIDE, LEUCINE AND GLUCOSE.
Topics: Adenoma, Islet Cell; Blood; Blood Chemical Analysis; Blood Glucose; Glucagon; Glucose; Humans; Hyperglycemia; Hyperinsulinism; Hypoglycemia; Insulin; Leucine; Pancreatic Neoplasms; Pharmacology; Surgical Procedures, Operative; Tolbutamide | 1964 |
CUSHING'S SYNDROME WITH HYPOGLYCEMIA CAUSED BY ADRENOCORTICAL CARCINOMA.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Neoplasms; Adrenocortical Carcinoma; Aldosterone; Anabolic Agents; Androsterone; Cushing Syndrome; Dexamethasone; Etiocholanolone; Humans; Hydrocortisone; Hypoglycemia; Leucine; Manganese; Pathology; Steroids; Tolbutamide; Urine | 1965 |
LIPOATROPHIC DIABETES. I. STUDIES CONCERNING ENDOCRINE FUNCTION AND CARBOHYDRATE METABOLISM.
Topics: Adolescent; Carbohydrate Metabolism; Diabetes Mellitus, Lipoatrophic; Diabetes Mellitus, Type 1; Drug Tolerance; Epinephrine; Fatty Acids; Glucagon; Glucose Tolerance Test; Hepatomegaly; Humans; Infant; Insulin; Insulin Resistance; L-Lactate Dehydrogenase; Leucine; Lipids; Lipodystrophy; Liver; Liver Cirrhosis; Liver Function Tests; Metyrapone; Pharmacology; Pituitary-Adrenal Function Tests; Radiography; Tolbutamide; Transaminases; Urine | 1965 |
EVIDENCE FAVORING THE SARCOMATOUS ORIGIN OF AN INSULIN-LIKE SUBSTANCE IN A CASE OF FIBROSARCOMA WITH HYPOGLYCEMIA.
Topics: Blood Glucose; Calcium Isotopes; Chemical Phenomena; Chemistry; Epinephrine; Fibrosarcoma; Glucagon; Glucose Tolerance Test; Growth Hormone; Human Growth Hormone; Humans; Hypoglycemia; Insulin; Leucine; Liver Neoplasms; Pathology; Prolactin; Radioisotopes; Radionuclide Imaging; Tolbutamide | 1965 |
Clinical features and insulin regulation in infants with a syndrome of prolonged neonatal hyperinsulinism.
Topics: Antihypertensive Agents; Calcium; Case-Control Studies; Diazoxide; Enteral Nutrition; Fasting; Female; Glucose; Humans; Hyperinsulinism; Hypoglycemia; Hypoglycemic Agents; Infant; Infant, Newborn; Infusions, Intravenous; Insulin; Insulin Secretion; Leucine; Male; Prospective Studies; Risk Factors; Sweetening Agents; Tolbutamide | 2006 |