Page last updated: 2024-08-16

tolbutamide and leucine

tolbutamide has been researched along with leucine in 185 studies

Research

Studies (185)

TimeframeStudies, this research(%)All Research%
pre-1990175 (94.59)18.7374
1990's9 (4.86)18.2507
2000's1 (0.54)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Grill, V; Rundfeldt, M1
Di Campo-Rougerie, C; Ramahandridona, G; Vague, P1
Berger, H1
Fischer, LJ; Rickert, DE1
Adcock, K; Austin, M; Duckworth, WC; Murrell, LR; Solomon, SS1
Garcia, SD; Jarrousse, C; Rosselin, G1
Macchi, IA; Zeytinoğlu, FN1
Ashcroft, SJ1
Kreines, K; Mako, ME; Starr, JI1
Come, SE; Eastman, RC; Gorden, P; Kahn, CR; Strewler, GJ1
Arends, J; Frerichs, H; Schauder, P1
Hudson, AJ; Tevaarwerk, GJ1
Arimura, A; Dobbs, RE; Harris, V; Ipp, E; Unger, RH; Vale, W1
Anderson, JH; Blackard, WG1
Boquist, L2
Di Campo-Rougerie, C; Mahmoud, F; Ramahandridona, G; Vague, P1
Alberti, KG; Marks, V1
Ogawa, S; Yoshinaga, T1
Levy, J; Malaisse, WJ1
Parman, AU1
Frerichs, H; Schauder, P1
Couropmitree, C; Freinkel, N; Hahnel, R; Horwitz, DL; Metzger, B; Nagel, TC; Rubenstein, AH1
Aarskog, D; Fluge, G; Stoa, KF1
Krämer, K; Sailer, FX1
Horwitz, DL; Kuzuya, H; Rubenstein, AH; Sandler, R1
Förster, VH1
Rathanaswami, P; Sundaresan, R2
Bedoya, FJ; Jeanrenaud, B1
Field, JB1
Ashford, ML; Carrington, CA; Hales, CN; Kozlowski, RZ; Sturgess, NC1
Henquin, JC; Hermans, MP; Schmeer, W1
Wolff, G2
Hodgins, DS; Kuo, JF; Kuo, WN1
Hellman, B; Sehlin, J; Täljedal, IB1
Ashcroft, SJ; Randle, PJ; Weerasinghe, LC1
Dunbar, JC; Foà, PP1
Dean, PM; Matthews, EK2
Mashimo, K; Nakagawa, M1
Miles, LE1
Drash, A; Schultz, R1
Lundbaek, K; Lyngsoe, J; Madsen, B; Orskov, H; Yde, H1
Greenwood, FC; Howorth, PJ; Marks, V; Samols, E1
Grumbach, MM; Kaplan, SL; Schotland, MG1
Lebovitz, HE; Pooler, K1
Antony, GJ; Underwood, LE; Van Wyk, JJ1
Smith, M1
Colwell, JA; Furey, WL1
Hung, W; Migeon, CJ1
Frawley, TF; Pensuwan, S1
Howell, SL; Taylor, KW1
Glöckner, E; Knoke, M; Markert, J; Reding, R1
Etheridge, JE1
Conn, JW; Fajans, SS; Floyd, JC; Harrison, TS; Knopf, RF; Thiffault, CA1
Sleisenger, MH; Walsh, JH1
Marks, V; Samols, E1
Dorner, M; Fontaine, R; Haarscher, A; Hasselmann, JL; Levy-Silagy, J; Schneegans, E1
Bryson, GH; Hume, DM; Williams, C1
Blaskovics, M; Donnell, GN; Kogut, MD1
Williams, C1
Abernethy, RJ; Buchanan, KD; McKiddie, MT1
Caquet, R1
Pi-Sunyer, FX; Van Itallie, TB; Zintel, HA1
DePeyster, FA1
Brooten, P; Felig, P; Landsberg, L; Sachs, FL1
Grinvalsky, HT; Remigio, PA1
Parmentier, J; Rubay, J1
Schwartz, JF; Zwiren, GT1
Cunningham, GR; Lebovitz, HE; Quickel, KE1
Gorden, P; Roth, J; Sherman, B1
Ashworth, MA; Milner, RD1
Marks, V1
Levey, GS; Mintz, DH; Schmidt, WM2
Corredor, DG; Danowski, TS; Dhawer, VP; Gonzalez, AR; Jung, Y; Khurana, RC; Klayton, R; Sieracki, JC1
Baker, L; Balsam, MJ; Bishop, HC; Hummeler, K; Kaye, R; Yakovac, WC1
Freinkel, N; Knopp, RH; Scheinin, JC1
Birchard, E; Cameron, GS; Cole, FM; Tuttle, RJ; Wright, AD1
Manusharova, RA; Nikolaev, OV; Veinberg, EG1
Howell, SL; Montague, W1
Basoli, A; Carboni, M; De Bernardinis, G; Patrassi, N; Perrotta, G1
Alsever, RN; Stjernholm, MR1
Lefebvre, P; Luyckx, A1
Ishihara, Y; Kuroda, A; Sato, N; Tajima, Y; Wada, Y1
Grögler, F; Lucke, C; Mitzkat, HJ1
Shapiro, JR; Sotoudeh, F1
Antony, GJ; Underwood, LE; Van den Brande, JL; Van Wyk, JJ; Voina, SJ1
Hirata, Y1
Gerich, J; Grodsky, GM; Karam, J; Levin, S; Sando, H1
Henquin, JC; Lambert, AE; Orci, L; Renold, AE1
Hinz, M; Maier, V; Nierle, C; Pfeiffer, EF; Schatz, H1
Tjioe, TO; Wacker, A1
Colle, E; Schiff, D; Stern, L; Wells, D1
Danowski, TS; Khurana, RC; Klayton, R; Nolan, S; Stephan, T1
Lavis, V; Sakai, T; Williams, RH1
Duprey, J; Lubetzki, J1
Blackard, WG; Kikuchi, M; Rabinovitch, A; Renold, AE1
Barbosa, J; Goetz, F; Kennedy, W; Nuttall, FQ1
Huff, TA; Lebovitz, HE1
Edgar, P; Merimee, TJ; Rabinowitz, D1
Isshiki, G; Ogawa, S; Okuno, G; Ueda, T; Yoshinaga, T1
Baker, RJ1
Costamaillere, L1
Hellerström, C; Schmidt, FH; Stork, H; Westman, S1
Haist, RE; Lin, BJ1
Hales, CN; Milner, RD3
Balant, L; Burr, IM; Grodsky, GM; Renold, AE; Stauffacher, W1
Misugi, K; Misugi, N; Smith, B; Sotos, J1
Korner, A; Morris, GE1
Wüstenberg, PW1
Chandra, P; Wacker, A; Wacker, D1
Christensen, HN; Tager, HS1
Underwood, LE; Van Wyk, JJ; Voina, SJ1
Aozi, O; Fujii, M; Okumura, K; Yokoo, S; Yoshida, H1
Aust, S; Theile, H1
Junod, A; Lambert, AE; Letarte, J; Stauffacher, W1
Kowalski, H; Lawecki, J; Rogala, H1
Mahler, RJ; Szabo, O1
Andreani, D; Fallucca, F; Javicoli, M; Tamburrano, G1
Basabe, JC; Lopez, NL; Viktora, JK; Wolff, FW1
Ambs, E; Brunnberg, J; Gekle, D1
Albeaux-Fernet, M1
Federspil, G; Frezzato, S; Macrì, C; Muggeo, M; Tiengo, A; Trisotto, A; Vianello, A1
Aylor, KW; Parry, DG1
DeChatelet, LR; McDonald, HJ4
Chiumello, G; Drash, A; Kenny, FM1
Farquhar, JW; Frank, A; Reaven, GM1
Christensen, HN; Cullen, AM1
Ehrlich, RM; Martin, JM1
Paulsen, EP; Velasco, MS1
Teller, W1
Friend, JA; Hales, CN1
Conason, EG; Most, S; Podolsky, S; Rifkin, H; Ross, H1
Colwell, AR1
Penttilä, IM1
Kenny, FM; Preeyasombat, C1
Correia, JP; DeMoura, MC; Madeira, F1
De Schepper, PJ1
Gishizky, ML; Gold, G; Grodsky, GM1
Abdel-Hamid, M; Ammon, HP; Enz, G; Rao, PG1
Henquin, JC; Tamagawa, T1
Bailbe, D; Giroix, MH; Kergoat, M; Picon, L; Portha, B1
Böhles, H1
Barnett, DW; Chern, HT; Misler, S; Pressel, DM; Scharp, DW1
Gross, R; Hillaire-Buys, D; Manteghetti, M; Ribes, G; Roye, M1
Martin, F; Reig, JA; Soria, B1
Bell, DA; Birkett, DJ; Ghanayem, BI; Goldstein, JA; Kaminsky, LS; Miners, JO; Shenfield, GM; Sullivan-Klose, TH; Zhang, ZY1
Hosaka, T; Oka, Y1
Balamurugan, AN; Gunasekaran, S; Ramakrishna, B1
Clark, A; de Koning, EJ; MacArthur, DL; Morris, JF; Verbeek, JS1
BALASH, WR; BONESSI, JV; DANOWSKI, TS; MOSES, C1
BONESSI, JV; DANOWSKI, TS; MOSES, C1
BRADHAM, R; BUSE, J; BUSE, MG; MARSHALL, JN; OBERMAN, H1
FRAWLEY, TF; PENSUWAN, S; YERRY, R; ZACHAREWICZ, F1
LANDON, J; SAMOLS, E; WYNN, V1
GERSHBERG, H; NADLER, HL; NEUMANN, LL1
BOSHELL, BR; KIRSCHENFELD, JJ; SOTERES, PS1
BAENS, GS; CORNBLATH, M; WYBREGT, SH1
BUTTERFIELD, WJ; JARRETT, RJ1
BOUMAN, PR1
CARNEVALI, R; POLI, E; RAINERI, P1
COLES, HM1
BAENS, GS; CORNBLATH, M; KLEIN, RI; WYBREGT, SH1
GRANN, V; MAHLER, RJ; PURDY, R1
LEVINE, R; MAHLER, R1
SCHOLTZ, DA1
BIELIK, E; GALIK, L; HRNCIAR, J; HRNCIAROVA, M1
FOA, PP1
AKIYAMA, Y; ISHIGAMI, R; KWATA, T; NATORI, H; OHMOTO, J; OKADA, H; SHIOTANI, S; YOSHIDA, A1
CONN, JW; FAJANS, SS; FLOYD, JC; KNOPF, RF1
EYMONTT, MJ; GWINUP, G; HAMWI, GJ; KRUGER, FA; MAYNARD, DE1
KELLEY, VC; RUVALCABA, RH; SAMOLS, E1
GINSBERG, DM1
CLARKE, DW; EHRLICH, R; EVANS, J; FORBATH, N; VOLPE, R1
Hoe, FM; Simmons, RA; Stanley, CA; Steinkrauss, L; Thornton, PS; Wanner, LA1

Reviews

23 review(s) available for tolbutamide and leucine

ArticleYear
The control of insulin release by sugars.
    Ciba Foundation symposium, 1976, Volume: 41

    Topics: Acetylglucosamine; Animals; Caffeine; Calcium; Carbohydrates; Cyclic AMP; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Leucine; Mice; Perfusion; Potassium; Rats; Receptors, Drug; Starvation; Tolbutamide

1976
Selected tests of carbohydrate metabolism.
    Clinics in endocrinology and metabolism, 1976, Volume: 5, Issue:3

    Topics: Adolescent; Adult; Blood Glucose; Carbohydrate Metabolism; Child; Clinical Laboratory Techniques; Diazoxide; Fasting; Female; Fructose; Galactose; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Inulin; Lactose; Leucine; Male; Middle Aged; Proinsulin; Time Factors; Tolbutamide

1976
Hypoglycemia. Definition, clinical presentations, classification, and laboratory tests.
    Endocrinology and metabolism clinics of North America, 1989, Volume: 18, Issue:1

    Topics: Blood Glucose; Calcium; Fever; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Hypothermia; Insulin; Leucine; Nervous System Diseases; Tolbutamide

1989
[Hypoglycemia. 3].
    Medizinische Monatsschrift, 1970, Volume: 24, Issue:7

    Topics: Animals; Arginine; Biguanides; Diazoxide; Dicumarol; Drug Synergism; Ethanol; Glucagon; Glucocorticoids; Glucose; Guinea Pigs; Humans; Hypoglycemia; Hypoglycemic Agents; Leucine; Mice; Rabbits; Rats; Sympatholytics; Tolbutamide; Xylitol

1970
Hypoglycemia: tolbutamide and leucine tests in insulinoma.
    The Medical clinics of North America, 1968, Volume: 52, Issue:2

    Topics: Adenoma, Islet Cell; Blood Glucose; Fasting; Female; Glucagon; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemia; Insulin; Insulin Secretion; Leucine; Male; Middle Aged; Pancreatic Neoplasms; Tolbutamide

1968
Hypoglycemia and the central nervous system.
    Pediatric clinics of North America, 1967, Volume: 14, Issue:4

    Topics: Adrenocorticotropic Hormone; Anticonvulsants; Brain; Child, Preschool; Diazoxide; Diet Therapy; Epinephrine; Fasting; Glucagon; Glucose; Glucose Tolerance Test; Humans; Hypoglycemia; Hypoxia; Infant; Infant, Newborn; Infant, Newborn, Diseases; Insulin; Leucine; Oxygen Consumption; Seizures; Tolbutamide; Zinc

1967
Functioning tumors of the pancreas.
    Medical times, 1968, Volume: 96, Issue:9

    Topics: Adenoma, Islet Cell; Diarrhea; Digestive System; Fasting; Gastrins; Glucagon; Glucose; Glucose Tolerance Test; Humans; Hypoglycemia; Hypokalemia; Leucine; Pancreatic Neoplasms; Tolbutamide; Zollinger-Ellison Syndrome

1968
Progress report. Diagnosis of insulinoma.
    Gut, 1971, Volume: 12, Issue:10

    Topics: Adenoma, Islet Cell; Angiography; Blood Glucose; Child; Child, Preschool; Diagnosis, Differential; Ethanol; Fasting; Glucagon; Glucose Tolerance Test; Hormones, Ectopic; Humans; Hypoglycemia; Infant; Infant, Newborn; Injections, Intravenous; Insulin; Leucine; Pancreatic Neoplasms; Parathyroid Neoplasms; Pituitary Neoplasms; Tolbutamide

1971
Diazoxide and the secretion of insulin.
    Nutrition reviews, 1972, Volume: 30, Issue:8

    Topics: Animals; Cyclic AMP; Diazoxide; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Pancreas; Perfusion; Rats; Theophylline; Tolbutamide

1972
[Insulinoma].
    Nihon rinsho. Japanese journal of clinical medicine, 1973, Volume: 31, Issue:3

    Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Angiography; Child; Diagnosis, Differential; Diagnostic Techniques, Surgical; Female; Glucagon; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemia; Insulin; Leucine; Male; Middle Aged; Pancreatic Neoplasms; Proinsulin; Tolbutamide

1973
[Hypoglycemia].
    Nihon rinsho. Japanese journal of clinical medicine, 1972, Volume: 30, Issue:11

    Topics: Blood Glucose; Ethanol; Fasting; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Iatrogenic Disease; Insulin; Insulin Antibodies; Leucine; Tolbutamide

1972
Synthesis and secretion of insulin in dynamic perfusion systems.
    Advances in metabolic disorders, 1974, Volume: 7, Issue:0

    Topics: Animals; Antimetabolites; Arginine; Carbon Radioisotopes; Computers; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Isotope Labeling; Leucine; Models, Biological; Obesity; Oligomycins; Pancreas; Perfusion; Rats; Time Factors; Tolbutamide

1974
[Hypoglycemia. 3].
    Medizinische Monatsschrift, 1968, Volume: 22, Issue:3

    Topics: Biguanides; Cyclophosphamide; Diet, Diabetic; Ethanol; Glucagon; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Leucine; Plant Poisoning; Sulfonamides; Sympathomimetics; Tolbutamide

1968
Newer considerations in the diagnosis and management of fasting hypoglycemia.
    The Surgical clinics of North America, 1969, Volume: 49, Issue:1

    Topics: Adult; Blood Glucose; Catecholamines; Celiac Artery; Child, Preschool; Fasting; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Leucine; Liver Function Tests; Radiography; Radioisotopes; Radionuclide Imaging; Selenium; Tolbutamide

1969
[Spontaneous hypoglycemias].
    Revista medica de Chile, 1969, Volume: 97, Issue:4

    Topics: Ethanol; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Leucine; Tolbutamide

1969
[The hypoglycemia syndrome].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1970, Jun-01, Volume: 25, Issue:11

    Topics: Alloxan; Angiography; Antibiotics, Antineoplastic; Blood Glucose; Diagnosis, Differential; Diazoxide; Diet Therapy; Epinephrine; Gastrointestinal Diseases; Glucagon; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemia; Leucine; Metabolic Diseases; Neoplasms; Pancreatic Neoplasms; Prednisone; Tolbutamide

1970
[The diagnosis of hypoglycemia in childhood (author's transl)].
    Klinische Padiatrie, 1980, Volume: 192, Issue:4

    Topics: Adolescent; Age Factors; Alanine; Child; Child, Preschool; Deoxyglucose; Glucagon; Glucose Tolerance Test; Hepatomegaly; Humans; Hypoglycemia; Infant; Infant, Newborn; Leucine; Time Factors; Tolbutamide

1980
[Tolbutamide, glucagon, leucine and arginine tolerance test].
    Nihon rinsho. Japanese journal of clinical medicine, 1997, Volume: 55 Suppl 2

    Topics: Arginine; Diabetes Mellitus; Glucagon; Humans; Hypoglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Pancreatic Function Tests; Tolbutamide

1997
[POSSIBILITIES AND LIMITATIONS IN THE DETERMINATION OF INSULIN IN BLOOD IN THE DIAGNOSIS OF HYPERINSULINISM].
    Maandschrift voor kindergeneeskunde, 1963, Volume: 31

    Topics: Adenoma, Islet Cell; Blood; Diagnosis; Humans; Hyperglycemia; Hyperinsulinism; Insulin; Leucine; Pancreatic Neoplasms; Tolbutamide

1963
PRODUCTION, SECRETION, AND AVAILABILITY OF INSULIN.
    Annual review of medicine, 1964, Volume: 15

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Blood Chemical Analysis; Chemical Phenomena; Chemistry; Growth Hormone; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Antibodies; Leucine; Metabolism; Tolbutamide

1964
[HYPERINSULINISM. DIAGNOSTIC AND THERAPEUTIC ASPECTS].
    Lekarska veda v zahranici, 1964, Mar-20, Volume: 37

    Topics: Diagnosis, Differential; Electrodiagnosis; Electroencephalography; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemia; Leucine; Pancreas; Sleep Wake Disorders; Surgical Procedures, Operative; Tolbutamide

1964
EXPERIMENTAL DIABETES AND THE MODE OF ACTION OF THE SULFONYLUREAS. WITH SOME SPECULATIONS ON THE PREVENTION OF DIABETES.
    Bulletin - Sinai Hospital of Detroit, 1964, Volume: 12

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Animals; Cortisone; Diabetes Mellitus; Diabetes Mellitus, Experimental; Fatty Acids; Fluoroacetates; Genetics, Medical; Glucagon; Glucose Tolerance Test; Humans; Hyperglycemia; Hypoglycemic Agents; Leucine; Pharmacology; Pregnancy; Prolactin; Rats; Research; Sulfonylurea Compounds; Tolbutamide

1964
HYPOGLYCEMIA ASSOCIATED WITH EXTRAPANCREATIC NEOPLASMS, WITH A NOTE ON OTHER UNUSUAL FORMS OF HYPOGLYCEMIA.
    Advances in internal medicine, 1964, Volume: 12

    Topics: Adrenogenital Syndrome; Carcinoma, Hepatocellular; Drug Therapy; Glycogen Storage Disease Type I; Humans; Hypoglycemia; Leucine; Liver Glycogen; Liver Neoplasms; Mesenchymoma; Neoplasms; Retroperitoneal Neoplasms; Thoracic Neoplasms; Tolbutamide

1964

Trials

1 trial(s) available for tolbutamide and leucine

ArticleYear
The use of insulin dynamics in the evaluation of streptozotocin therapy of malignant insulinomas.
    The Journal of clinical endocrinology and metabolism, 1971, Volume: 33, Issue:3

    Topics: Adenoma, Islet Cell; Adult; Alkaline Phosphatase; Antibiotics, Antineoplastic; Aspartate Aminotransferases; Blood Glucose; Carbon Dioxide; Chlorides; Clinical Trials as Topic; Female; Glucose Tolerance Test; Hematocrit; Humans; Insulin; Insulin Secretion; Leucine; Leukocyte Count; Middle Aged; Potassium; Sodium; Specific Gravity; Sulfobromophthalein; Tolbutamide; Urine

1971

Other Studies

161 other study(ies) available for tolbutamide and leucine

ArticleYear
Effects of priming with D-glucose on insulin secretion from rat pancreatic islets: increased responsiveness to other secretagogues.
    Endocrinology, 1979, Volume: 105, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Adenine; Alloxan; Animals; Barium; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Perfusion; Rats; Tolbutamide

1979
[Effect of glucose and of insulin on the fast induced decrease of insulin response to glucose of the in vitro perfused rat pancreas].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1975, Volume: 169, Issue:3

    Topics: Animals; Fasting; Glucose; Insulin; Insulin Secretion; Leucine; Male; Pancreas; Perfusion; Rats; Secretory Rate; Stimulation, Chemical; Tolbutamide

1975
Hypoglycemia: a perspective.
    Postgraduate medicine, 1975, Volume: 57, Issue:2

    Topics: Adenoma, Islet Cell; Citric Acid Cycle; Diabetes Complications; Diazoxide; Female; Glucose; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemia; Insulin; Leucine; Liver; Liver Diseases; Middle Aged; Muscles; Pancreatic Neoplasms; Streptozocin; Tolbutamide

1975
Cyproheptadine and beta cell function in the rat: insulin secretion from pancreas segments in vitro.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1975, Volume: 150, Issue:1

    Topics: Administration, Oral; Animals; Bucladesine; Cyproheptadine; Dose-Response Relationship, Drug; Glucagon; Glucose; In Vitro Techniques; Injections, Intraperitoneal; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Rats; Tolbutamide

1975
Human islet cell adenoma: metabolic analysis of the patient and of tumor cells in monolayer culture.
    Diabetologia, 1975, Volume: 11, Issue:6

    Topics: Adenoma, Islet Cell; Adult; Cell Survival; Cells, Cultured; Culture Media; Cyclic AMP; Glucagon; Glucose; Humans; In Vitro Techniques; Insulin; Insulin Secretion; Leucine; Male; Proinsulin; Theophylline; Tolbutamide

1975
Biosynthesis of proinsulin and insulin in newborn rat pancreas. Interaction of glucose, cyclic AMP, somatostatin, and sulfonylureas on the (3H) leucine incorporation into immunoreactive insulin.
    The Journal of clinical investigation, 1976, Volume: 57, Issue:1

    Topics: Animals; Animals, Newborn; Antigens; Cyclic AMP; Glipizide; Glucose; Humans; Insulin; Islets of Langerhans; Leucine; Proinsulin; Rats; Somatostatin; Sulfonylurea Compounds; Theophylline; Tolbutamide

1976
Hyaluronidase-induced inhibition of the insulinotropic action of sulfonylureas, leucine, and glucagon in rodent isolated pancreatic islets.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1976, Volume: 8, Issue:2

    Topics: Animals; Chlorpropamide; Cricetinae; Female; Glucagon; Glucose; Glyburide; Hyaluronoglucosaminidase; Insulin; Islets of Langerhans; Leucine; Mice; Microbial Collagenase; Rats; Species Specificity; Sulfonylurea Compounds; Tolbutamide

1976
Insulin and proinsulin metabolism in an unusual case of insulinoma.
    The Ohio State medical journal, 1976, Volume: 72, Issue:12

    Topics: Adenoma, Islet Cell; Glucagon; Glucose Tolerance Test; Humans; Insulin; Leucine; Male; Middle Aged; Proinsulin; Tolbutamide

1976
Adriamycin therapy for advanced insulinoma.
    The Journal of clinical endocrinology and metabolism, 1977, Volume: 44, Issue:1

    Topics: Adenoma, Islet Cell; Adult; Blood Glucose; Diazoxide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Glucagon; Humans; Insulin; Leucine; Male; Middle Aged; Prednisone; Streptozocin; Tolbutamide

1977
Onset and reversibility of changes in secretory function and composition of isolated rat pancreatic islets following long-term administrationof high or low tolbutamide doses.
    Metabolism: clinical and experimental, 1977, Volume: 26, Issue:1

    Topics: Animals; Blood Glucose; Glucagon; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Leucine; Male; Rats; Theophylline; Time Factors; Tolbutamide

1977
Carbohydrate metabolism and insulin resistance in myotonia dystrophica.
    The Journal of clinical endocrinology and metabolism, 1977, Volume: 44, Issue:3

    Topics: Adult; Aged; Arginine; Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus; Female; Fructose; Galactose; Glucagon; Glucose Tolerance Test; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Leucine; Male; Middle Aged; Myotonic Dystrophy; Sorbitol; Tolbutamide; Xylose

1977
Release of immunoreactive somatostatin from the pancreas in response to glucose, amino acids, pancreozymin-cholecystokinin, and tolbutamide.
    The Journal of clinical investigation, 1977, Volume: 60, Issue:3

    Topics: Amino Acids; Animals; Antigens; Cholecystokinin; Dogs; Glucose; Islets of Langerhans; Leucine; Male; Somatostatin; Tolbutamide

1977
Effect of lithium on pancreatic islet insulin release.
    Endocrinology, 1978, Volume: 102, Issue:1

    Topics: Animals; Calcium; Choline; Culture Techniques; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Lithium; Male; Rats; Tolbutamide

1978
Differences in the blood glucose response of mice to alloxan and alloxan-inhibiting compounds.
    Acta endocrinologica, 1979, Volume: 92, Issue:4

    Topics: Acetazolamide; Alloxan; Animals; Bicarbonates; Blood Glucose; Deoxy Sugars; Diabetes Mellitus, Experimental; Eating; Hydroxymercuribenzoates; Lactates; Leucine; Mannoheptulose; Mice; Mice, Inbred C57BL; Phenytoin; Starvation; Tolbutamide

1979
Kinetics of the early insulin response of the perfused rat pancreas to various metabolites and tolbutamide.
    Diabete & metabolisme, 1975, Volume: 1, Issue:3

    Topics: Animals; Caproates; Glucose; Glyceraldehyde; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Rats; Stimulation, Chemical; Time Factors; Tolbutamide; Valerates

1975
Electron microscopic study on zinc in B cells of pancreatic islets of rat under conditions stimulating the excretion of insulin.
    Acta histochemica, 1975, Volume: 53, Issue:2

    Topics: Animals; Chlorpropamide; Cytoplasmic Granules; Glucose; Histocytochemistry; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Protein Binding; Rats; Sulfides; Tolbutamide; Zinc

1975
The stimulus-secretion coupling of glucose-induced insulin release-XVII. Effects of sulfonylureas and diazoxide on insular biosynthetic activity.
    Biochemical pharmacology, 1975, Jan-15, Volume: 24, Issue:2

    Topics: Animals; Cyclohexanes; Cyclopentanes; Diazoxide; Glucose; Hormones; In Vitro Techniques; Insulin; Islets of Langerhans; Leucine; Oxidation-Reduction; Peptide Biosynthesis; Proinsulin; Pyrazines; Pyrroles; Rats; Sulfonylurea Compounds; Tolbutamide

1975
Effects of hypophysectomy and short-term growth hormone replacement on insulin release from and glucose metabolism in isolated rat islets of Langerhans.
    The Journal of endocrinology, 1975, Volume: 67, Issue:1

    Topics: Adrenal Glands; Animals; Arginine; Blood Urea Nitrogen; Body Weight; Butyrates; Cattle; Citrates; Eating; Glucose; Glycogen; Growth Hormone; Hypophysectomy; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Organ Size; Pancreas; Phosphates; Pituitary Gland; Rats; RNA; Serum Albumin; Time Factors; Tolbutamide; Xylitol

1975
Tolbutamide-induced changes of the DNA, protein and insulin content and the secretory activity of isolated rat pancreatic islets.
    Diabetologia, 1975, Volume: 11, Issue:4

    Topics: Animals; DNA; Glucose; Hyperplasia; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Proteins; Rats; Theophylline; Tolbutamide

1975
Plasma C-peptide and diagnosis of factitious hyperinsulinism. Study of an insulin-dependent diabetic patient with "spontaneous" hypoglycemia.
    Annals of internal medicine, 1975, Volume: 82, Issue:2

    Topics: Diabetes Mellitus; Diagnosis, Differential; Glucagon; Glucose; Humans; Hyperinsulinism; Hypoglycemia; Insulin; Iodine Radioisotopes; Leucine; Male; Middle Aged; Peptides; Radioimmunoassay; Substance-Related Disorders; Tolbutamide

1975
Endocrinological aspects at follow-up studies in neonatal hypoglycaemia.
    Acta paediatrica Scandinavica, 1975, Volume: 64, Issue:2

    Topics: Blood Glucose; Child, Preschool; Fatty Acids, Nonesterified; Follow-Up Studies; Glucose Tolerance Test; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Infant, Newborn; Infant, Newborn, Diseases; Insulin; Leucine; Stimulation, Chemical; Tolbutamide

1975
[Diagnosis of organic hyperinsulinism].
    Anasthesiologische und intensivmedizinische Praxis, 1975, Volume: 10, Issue:1

    Topics: Diagnosis, Differential; Diazoxide; Fasting; Glucagon; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemia; Leucine; Radiography; Radionuclide Imaging; Tolbutamide

1975
Hypoglycemia and endogenous hyperinsulinism complicating diabetes mellitus. Application of the C-peptide assay to diagnosis and therapy.
    The American journal of medicine, 1975, Volume: 59, Issue:5

    Topics: Blood Glucose; Diabetes Complications; Diabetes Mellitus; Growth Hormone; Humans; Hyperinsulinism; Hypoglycemia; Leucine; Male; Middle Aged; Pancreatectomy; Peptides; Tolbutamide

1975
[Hypoglycemia. Series 2: symptoms, diagnosis].
    Fortschritte der Medizin, 1976, Feb-05, Volume: 94, Issue:4

    Topics: Adult; Blood Glucose; Catecholamines; Fatigue; Female; Glucagon; Glucose Tolerance Test; Headache; Humans; Hunger; Hypoglycemia; Infant; Infant, Newborn; Insulin; Keto Acids; Leucine; Neurologic Manifestations; Pregnancy; Tolbutamide

1976
Effects of thiamine deficiency on the biosynthesis of insulin in rats.
    Biochemistry international, 1991, Volume: 24, Issue:6

    Topics: Animals; Glucose; Insulin; Leucine; Pancreas; Proinsulin; Rats; Rats, Inbred Strains; Thiamine Deficiency; Tolbutamide

1991
Insulin secretory response to secretagogues by perifused islets from chronically glucose-infused rats.
    Diabetes, 1991, Volume: 40, Issue:1

    Topics: Animals; Colforsin; Glucose; In Vitro Techniques; Infusions, Intravenous; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Kinetics; Leucine; Male; Perfusion; Rats; Rats, Mutant Strains; Tetradecanoylphorbol Acetate; Thinness; Tolbutamide

1991
Effects of insulin secretagogues on the secretion of insulin during thiamine deficiency.
    Biochemistry international, 1988, Volume: 17, Issue:3

    Topics: Animals; Arginine; Blood Glucose; Insulin; Insulin Secretion; Leucine; Rats; Rats, Inbred Strains; Thiamine Deficiency; Tolbutamide

1988
Effects of sulphonylureas and diazoxide on insulin secretion and nucleotide-sensitive channels in an insulin-secreting cell line.
    British journal of pharmacology, 1988, Volume: 95, Issue:1

    Topics: Adenosine Triphosphate; Animals; Cell Line; Diazoxide; Electrophysiology; Glucose; Glyburide; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Nucleotides; Potassium Channels; Rats; Sulfonylurea Compounds; Tolbutamide

1988
Modulation of the effect of acetylcholine on insulin release by the membrane potential of B cells.
    Endocrinology, 1987, Volume: 120, Issue:5

    Topics: Acetylcholine; Animals; Arginine; Calcium Radioisotopes; Cell Membrane; Diazoxide; Female; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Membrane Potentials; Mice; Potassium; Radioisotopes; Rubidium; Tolbutamide

1987
Regulation by various hormones and agents of adenosine-3',5'-monophosphate levels in islets of Langerhans of rats.
    Biochemical pharmacology, 1974, May-01, Volume: 23, Issue:9

    Topics: Adenine; Adrenergic beta-Antagonists; Adrenocorticotropic Hormone; Animals; Cresols; Cyclic AMP; Epinephrine; Glucagon; Glucose; Guanosine Triphosphate; Hormones; In Vitro Techniques; Islets of Langerhans; Isoproterenol; Leucine; Phenformin; Phenoxybenzamine; Phentolamine; Propanolamines; Propranolol; Propylamines; Prostaglandins; Rats; Receptors, Adrenergic; Secretin; Sotalol; Theophylline; Thyrotropin; Tolbutamide; Tritium

1974
The pancreatic -cell recognition of insulin secretagogues. IV. Islet uptake of sulfonylureas.
    Diabetologia, 1973, Volume: 9, Issue:3

    Topics: Animals; Antimycin A; Carbon Isotopes; Chlorpromazine; Diazoxide; Glucose; Glyburide; In Vitro Techniques; Islets of Langerhans; Leucine; Male; Mice; Serum Albumin; Sulfur Isotopes; Tolbutamide

1973
Interrelationship of islet metabolism, adenosine triphosphate content and insulin release.
    The Biochemical journal, 1973, Volume: 132, Issue:2

    Topics: Adenosine Triphosphate; Animals; Carbon Isotopes; Glucose; Glyburide; Glyceraldehyde; Heptoses; Hexoses; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Mice; Models, Biological; Nitriles; Oxidative Phosphorylation; Phenylhydrazines; Time Factors; Tolbutamide; Uncoupling Agents

1973
An inhibitory effect of tolbutamide and glibenclamide (glyburide) on the pancreatic islets of normal animals.
    Diabetologia, 1974, Volume: 10, Issue:1

    Topics: Animals; Blood Glucose; Carbon Radioisotopes; Female; Glucose; Glyburide; Insulin; Islets of Langerhans; Leucine; Tolbutamide

1974
The bioelectrical properties of pancreatic islet cells: effects of diabetogenic agents.
    Diabetologia, 1972, Volume: 8, Issue:3

    Topics: Action Potentials; Alloxan; Animals; Anti-Bacterial Agents; Diabetes Mellitus, Experimental; Female; Glucosamine; Glucose; Glutathione; Glyceraldehyde; Heptoses; In Vitro Techniques; Islets of Langerhans; Leucine; Male; Mice; Niacinamide; Nitroso Compounds; Tolbutamide; Urea

1972
[Insuloma; on endocrine function].
    Naika. Internal medicine, 1965, Volume: 16, Issue:6

    Topics: Adenoma, Islet Cell; Humans; Hyperglycemia; In Vitro Techniques; Insulin; Leucine; Tolbutamide

1965
Biochemical studies in a patient with hyperinsulinism.
    The New Zealand medical journal, 1966, Volume: 65, Issue:406

    Topics: Adenoma, Islet Cell; Adult; Female; Glucagon; Glucose Tolerance Test; Humans; Hydrocortisone; Hyperinsulinism; Hypoglycemia; Leucine; Pancreatic Neoplasms; Tolbutamide

1966
Islet cell adenoma in childhood: report of a case.
    Pediatrics, 1967, Volume: 39, Issue:1

    Topics: Adenoma; Adenoma, Islet Cell; Catecholamines; Child; Electroencephalography; Epinephrine; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Intelligence Tests; Leucine; Male; Tolbutamide

1967
The diagnosis of insuloma.
    Acta medica Scandinavica, 1967, Volume: 181, Issue:3

    Topics: Adenoma, Islet Cell; Adult; Aged; Diagnosis, Differential; Fasting; Female; Glucagon; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemia; Leucine; Male; Middle Aged; Radiography; Tolbutamide

1967
Plasma growth hormone levels in spontaneous hypoglycemia.
    The Journal of clinical endocrinology and metabolism, 1967, Volume: 27, Issue:4

    Topics: Adenoma, Islet Cell; Adrenal Gland Diseases; Adult; Aged; Carcinoma; Cholangitis; Deficiency Diseases; Fasting; Female; Fluorometry; Glucose; Glucose Tolerance Test; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Immunoassay; Insulin; Leucine; Lung Neoplasms; Male; Middle Aged; Pancreatitis; Sertoli-Leydig Cell Tumor; Stomach Neoplasms; Tolbutamide

1967
The tolbutamide tolerance texxt in the evaluation of childhood hypoglycemia.
    Pediatrics, 1967, Volume: 39, Issue:6

    Topics: Acidosis; Adenoma, Islet Cell; Child; Child, Preschool; Diagnosis, Differential; Humans; Hypoglycemia; Infant; Leucine; Tolbutamide

1967
ACTH-mediated insulin secretion: effect of aminophylline.
    Endocrinology, 1967, Volume: 81, Issue:3

    Topics: Adenine Nucleotides; Adrenalectomy; Adrenocorticotropic Hormone; Aminophylline; Animals; Blood Glucose; Carbon Isotopes; Glucagon; Glucose; Insulin; Islets of Langerhans; Leucine; Male; Mice; Phosphoric Monoester Hydrolases; Protein Biosynthesis; Tolbutamide

1967
Studies in hypoglycemia of infancy and childhood. Diagnosis and treatment.
    American journal of diseases of children (1960), 1967, Volume: 114, Issue:4

    Topics: Adenoma, Acidophil; Adolescent; Blood Glucose; Child; Child, Preschool; Diet Therapy; Epinephrine; Female; Glucagon; Glucocorticoids; Glucose Tolerance Test; Humans; Hypoglycemia; Hypopituitarism; Infant; Insulin; Leucine; Male; Pancreatectomy; Tolbutamide

1967
Insulin-secreting islet-cell tumours of the pancreas.
    The Australian and New Zealand journal of surgery, 1967, Volume: 37, Issue:2

    Topics: Adenoma, Islet Cell; Adult; Duodenum; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Pancreatectomy; Pancreatic Neoplasms; Tolbutamide

1967
Insulin secretion by insuloma and normal pancreas slices. Studies in a patient with multiple endocrine adenomata.
    Diabetes, 1968, Volume: 17, Issue:2

    Topics: Adenoma; Adenoma, Islet Cell; Adult; Female; Glucose; Glucose Tolerance Test; Humans; In Vitro Techniques; Insulin; Leucine; Mannose; Pancreas; Pancreatectomy; Pancreatic Neoplasms; Parathyroid Neoplasms; Polycystic Kidney Diseases; Tolbutamide

1968
Hypoglycemia in a two-year-old boy with adrenocorticotropic hormone (ACTH) deficiency (probably isolated) and adrenal medullary unresponsiveness to insulin-induced hypoglycemia.
    The Journal of clinical endocrinology and metabolism, 1968, Volume: 28, Issue:2

    Topics: Adrenal Insufficiency; Adrenal Medulla; Adrenocorticotropic Hormone; Blood Glucose; Catecholamines; Child, Preschool; Epinephrine; Glucose Tolerance Test; Humans; Hypoglycemia; Hypopituitarism; Insulin Coma; Leucine; Male; Norepinephrine; Pituitary-Adrenal Function Tests; Tolbutamide; Transferases

1968
Potassium ions and the secretion of insulin by islets of Langerhans incubated in vitro.
    The Biochemical journal, 1968, Volume: 108, Issue:1

    Topics: Animals; Depression, Chemical; Glucose; Immunoassay; In Vitro Techniques; Insulin; Insulin Secretion; Iodine Isotopes; Islets of Langerhans; Leucine; Male; Methods; Microbial Collagenase; Ouabain; Pancreas; Potassium; Potassium Isotopes; Rabbits; Stimulation, Chemical; Tolbutamide; Tritium

1968
[Current methods of study and morphologic findings in B-cell adenoma of the pancreas].
    Zentralblatt fur Chirurgie, 1967, Volume: 92, Issue:26a Pt 1

    Topics: Adenoma, Islet Cell; Adolescent; Blood Glucose; Diagnosis, Differential; Female; Glucose Tolerance Test; Humans; Hyperinsulinism; Leucine; Microscopy, Electron; Pancreas; Pancreatic Neoplasms; Tolbutamide

1967
Further studies on diazoxide suppression of insulin release from abnormal and normal islet tissue in man.
    Annals of the New York Academy of Sciences, 1968, Apr-11, Volume: 150, Issue:2

    Topics: Adenoma, Islet Cell; Arginine; Blood Glucose; Catecholamines; Depression, Chemical; Diazoxide; Female; Glucagon; Glucose; Humans; Hyperglycemia; Hyperinsulinism; Hypoglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Tolbutamide; Trichlormethiazide

1968
Glucagon test for insulinoma: a chemical study in 25 cases.
    Journal of clinical pathology, 1968, Volume: 21, Issue:3

    Topics: Adenoma, Islet Cell; Adult; Blood Glucose; Diagnosis, Differential; Female; Glucagon; Humans; Hyperinsulinism; Hypoglycemia; Insulin; Leucine; Male; Middle Aged; Tolbutamide

1968
[Apropos of a case of severe hypoglycemia. Present possibilities of diagnosis and treatment].
    Annales de pediatrie, 1968, Oct-02, Volume: 15, Issue:10

    Topics: Adenoma, Islet Cell; Blood Glucose; Diagnosis, Differential; Diazoxide; Glucocorticoids; Glucose; Glucose Tolerance Test; Humans; Hypoglycemia; Infant; Insulin; Leucine; Male; Pancreatectomy; Tolbutamide

1968
Islet cell tumors and hypoglycemia.
    Annals of surgery, 1969, Volume: 169, Issue:5

    Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Child; Fasting; Female; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Infant; Infant, Newborn; Insulin; Insulin Secretion; Leucine; Male; Middle Aged; Radiography; Tolbutamide

1969
Idiopathic hypoglycemia: a study of twenty-six children.
    The Journal of pediatrics, 1969, Volume: 74, Issue:6

    Topics: Adrenocorticotropic Hormone; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Diabetes Mellitus; Diet Therapy; Electroencephalography; Female; Glucose Tolerance Test; Humans; Hypoglycemia; Infant; Infant, Newborn; Infant, Newborn, Diseases; Insulin; Insulin Secretion; Intellectual Disability; Leucine; Liver Glycogen; Male; Neurologic Manifestations; Pancreatectomy; Prednisone; Pregnancy; Tolbutamide

1969
Islet cell tumors of the pancreas.
    Virginia medical monthly, 1969, Volume: 96, Issue:3

    Topics: Adenoma, Islet Cell; Aged; Fasting; Female; Humans; Hypoglycemia; Insulin; Leucine; Male; Middle Aged; Pancreatic Neoplasms; Tolbutamide

1969
Plasma insulin studies in the diagnosis of insulinoma.
    Scottish medical journal, 1969, Volume: 14, Issue:6

    Topics: Adenoma, Islet Cell; Adult; Aged; Blood Glucose; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Leucine; Male; Middle Aged; Pancreatic Neoplasms; Tolbutamide

1969
[Alcoholic hypoglycemia in adults].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1968, Nov-14, Volume: 44, Issue:47

    Topics: Adult; Alcoholism; Diet; Glucagon; Glucose Tolerance Test; Hepatic Encephalopathy; Humans; Hypoglycemia; Insulin; Leucine; NAD; Socioeconomic Factors; Tolbutamide

1968
Insulin stimulatory tests in a patient with islet cell adenoma.
    American journal of surgery, 1969, Volume: 118, Issue:1

    Topics: Adenoma, Islet Cell; Aged; Antigen-Antibody Reactions; Blood Glucose; Fasting; Female; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Insulin Antibodies; Insulin Secretion; Leucine; Methods; Tolbutamide

1969
Planning the appropriate operations for islet cell tumors of the pancreas.
    The Surgical clinics of North America, 1970, Volume: 50, Issue:1

    Topics: Adenoma, Islet Cell; Angiography; Blood Glucose; Glucose Tolerance Test; Humans; Leucine; Neoplasm Metastasis; Pancreatic Neoplasms; Radionuclide Imaging; Tolbutamide

1970
Medical grand rounds at Yale-New Haven Hospital. Diagnosis and management of hypoglycemia.
    Connecticut medicine, 1970, Volume: 34, Issue:3

    Topics: Adenoma, Islet Cell; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Leucine; Pancreatic Neoplasms; Tolbutamide

1970
Islet cell tumor with hypoglycemia.
    American family physician, 1971, Volume: 3, Issue:3

    Topics: Adenoma, Islet Cell; Adolescent; Adult; Female; Glucagon; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemia; Insulin; Leucine; Middle Aged; Pancreatectomy; Pancreatic Neoplasms; Radioimmunoassay; Tolbutamide

1971
[2 cases of Langerhans adenoma].
    Acta chirurgica Belgica, 1969, Volume: 68, Issue:4

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma, Islet Cell; Adult; Aged; Angiography; Celiac Artery; Female; Gastrointestinal Hemorrhage; Glucagon; Humans; Hypoglycemia; Insulin; Intracranial Arteriosclerosis; Leucine; Mesenteric Arteries; Obesity; Pancreatectomy; Pancreatic Neoplasms; Pregnancy; Pregnancy Complications; Prognosis; Tolbutamide

1969
Islet cell adenomatosis and adenoma in an infant.
    The Journal of pediatrics, 1971, Volume: 79, Issue:2

    Topics: Adenoma, Islet Cell; Adrenocorticotropic Hormone; Diazoxide; Glucose; Humans; Hypoglycemia; Infant, Newborn; Infant, Newborn, Diseases; Intellectual Disability; Leucine; Male; Pancreatectomy; Pancreatic Neoplasms; Prednisone; Tolbutamide

1971
Proinsulin-like component of circulating insulin in the basal state and in patients and hamsters with islet cell tumors.
    The Journal of clinical investigation, 1971, Volume: 50, Issue:10

    Topics: Acromegaly; Adenoma, Islet Cell; Adolescent; Adult; Animals; Child; Chromatography, Gel; Cricetinae; Cushing Syndrome; Diazoxide; Disease Models, Animal; Female; Glucagon; Glucose Tolerance Test; Half-Life; Humans; Hypoglycemia; Hypokalemia; Insulin; Iodine Isotopes; Leucine; Male; Middle Aged; Myotonic Dystrophy; Neoplasms, Experimental; Obesity; Proinsulin; Radioimmunoassay; Stimulation, Chemical; Tolbutamide

1971
Insulin release from human fetal pancreas in vitro.
    Archives of disease in childhood, 1971, Volume: 46, Issue:249

    Topics: Arginine; Barium; Body Weight; Cyclic AMP; Female; Fetus; Gestational Age; Glucagon; Glucose; Humans; In Vitro Techniques; Insulin; Insulin Secretion; Leucine; Ouabain; Pancreas; Potassium; Pregnancy; Theophylline; Tolbutamide

1971
Activation of adenyl cyclase in a pancreatic islet cell adenoma by glucagon and tolbutamide.
    Metabolism: clinical and experimental, 1972, Volume: 21, Issue:2

    Topics: Adenoma, Islet Cell; Adenosine Triphosphate; Adenylyl Cyclases; Administration, Oral; Arginine; Blood Glucose; Cyclic AMP; Enzyme Activation; Fasting; Fluorides; Glucagon; Glucose; Humans; Hypoglycemia; In Vitro Techniques; Injections, Intravenous; Insulin; Insulin Secretion; Leucine; Male; Middle Aged; Phosphorus Isotopes; Tolbutamide

1972
Insulin and glucose patterns in control subjects and in proved insulinoma.
    The American journal of the medical sciences, 1971, Volume: 262, Issue:2

    Topics: Adenoma, Islet Cell; Adult; Aged; Blood Glucose; Child; False Negative Reactions; Fasting; Female; Glucagon; Humans; Hypoglycemia; Insulin; Leucine; Male; Middle Aged; Pancreatic Neoplasms; Time Factors; Tolbutamide

1971
Beta cell adenoma in a child with hypoglycemia controlled with diazoxide.
    The Journal of pediatrics, 1972, Volume: 80, Issue:5

    Topics: Adenoma, Islet Cell; Blood Glucose; Child, Preschool; Diazoxide; Female; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Leucine; Microscopy, Electron; Pancreatectomy; Pancreatic Neoplasms; Splenectomy; Tolbutamide

1972
Diphenylhydantoin and an insulin-secreting islet adenoma.
    Archives of internal medicine, 1972, Volume: 130, Issue:6

    Topics: Adenoma, Islet Cell; Adult; Blood Glucose; Epilepsy, Tonic-Clonic; Glucagon; Humans; Insulin; Insulin Secretion; Leucine; Male; Nitrogen; Pancreas; Phenytoin; Tolbutamide

1972
Insulinoma diagnosed by insulin immunoassay and angiography.
    Journal of pediatric surgery, 1972, Volume: 7, Issue:6

    Topics: Adenoma, Islet Cell; Angiography; Blood Glucose; Child; Humans; Hypoglycemia; Immunoassay; Insulin; Leucine; Male; Pancreatic Neoplasms; Proinsulin; Tolbutamide

1972
Various tests in the evaluation of islet cell adenomas.
    JFMA, the Journal of the Florida Medical Association. Florida Medical Association, 1973, Volume: 60, Issue:2

    Topics: Adenoma, Islet Cell; Blood Glucose; Fasting; Glucagon; Humans; Insulin; Leucine; Male; Middle Aged; Pancreatic Neoplasms; Proinsulin; Tolbutamide

1973
[Comparative evaluation of the tolbutamide and leucine tests in insulinoma].
    Khirurgiia, 1972, Volume: 48, Issue:8

    Topics: Adenoma, Islet Cell; Adolescent; Adult; Female; Humans; Leucine; Male; Middle Aged; Tolbutamide

1972
The mode of action of adenosine 3':5'-cyclic monophosphate in mammalian islets of Langerhans. Effects of insulin secretagogues on islet-cell protein kinase activity.
    The Biochemical journal, 1973, Volume: 134, Issue:1

    Topics: Animals; Arginine; Caffeine; Cyclic AMP; Diazoxide; Epinephrine; Glucagon; Glyburide; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Phosphorus Isotopes; Phosphotransferases; Protein Kinases; Rats; Theophylline; Time Factors; Tolbutamide; Xanthines; Xylitol

1973
[Functioning beta-insular tumors of the pancreas. Principal diagnostic tests].
    Folia endocrinologica, 1973, Volume: 26, Issue:5

    Topics: Adenoma, Islet Cell; Aortography; Blood Glucose; Fasting; Glucose Tolerance Test; Humans; Leucine; Methods; Pancreatic Neoplasms; Radionuclide Imaging; Tolbutamide

1973
Current concepts in diagnosis of insulinoma.
    Rocky Mountain medical journal, 1974, Volume: 71, Issue:4

    Topics: Adenoma, Islet Cell; Blood Glucose; Fasting; Glucagon; Humans; Hypoglycemia; Insulin; Leucine; Proinsulin; Tolbutamide

1974
[Exploration of hypoglycemia].
    Revue medicale de Liege, 1974, Apr-15, Volume: 29, Issue:8

    Topics: Adenoma, Islet Cell; Arginine; Blood Glucose; Diazoxide; Diet; Fasting; Glucagon; Hormones, Ectopic; Humans; Hypoglycemia; Insulin; Insulin Secretion; Leucine; Medical History Taking; Pancreatic Neoplasms; Physical Examination; Time Factors; Tolbutamide

1974
[Atypical case of insulinoma (author's transl)].
    Medizinische Klinik, 1974, Sep-06, Volume: 69, Issue:36

    Topics: Adenoma, Islet Cell; Angiography; Blood Glucose; Fasting; Female; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Leucine; Middle Aged; Pancreatic Neoplasms; Tolbutamide; Ultrasonography

1974
The diagnostic evaluation of the patient with hypoglycemic symptoms.
    The Medical annals of the District of Columbia, 1972, Volume: 41, Issue:1

    Topics: Adrenal Glands; Diagnosis, Differential; Fasting; Glucose Tolerance Test; Humans; Hyperventilation; Hypoglycemia; Hypotension; Leucine; Pheochromocytoma; Radiography; Sella Turcica; Thyroid Gland; Tolbutamide

1972
Islet cell function and glucose homeostasis in hypopituitary dwarfism: synergism between growth hormone and cortisone.
    The Journal of pediatrics, 1973, Volume: 82, Issue:1

    Topics: Blood Glucose; Child; Cortisone; Drug Synergism; Dwarfism, Pituitary; Female; Glucose; Glucose Tolerance Test; Growth Hormone; Homeostasis; Humans; Hypoglycemia; Insulin; Islets of Langerhans; Leucine; Male; Pregnancy; Tolbutamide

1973
Enzyme-induced modifications of beta cell function. I. Effect of pronase on insulin secretion.
    European journal of clinical investigation, 1974, Dec-05, Volume: 4, Issue:6

    Topics: Animals; Cell Membrane; Glucose; Guinea Pigs; Insulin; Insulin Secretion; Iodine Radioisotopes; Islets of Langerhans; Leucine; Male; Perfusion; Pronase; Rabbits; Rats; Swine; Tolbutamide

1974
The effect of tolbutamide and glibenclamide on the incorporation of ( 3 H)leucine and on the conversion of proinsulin to insulin in isolated pancreatic islets.
    FEBS letters, 1972, Oct-01, Volume: 26, Issue:1

    Topics: Animals; Chromatography, Gel; Depression, Chemical; Glucose; Glyburide; Insulin; Insulin Secretion; Islets of Langerhans; Isotope Labeling; Leucine; Male; Mice; Proinsulin; Rats; Time Factors; Tolbutamide; Tritium

1972
[The effect of oral antidiabetics on the biosynthesis of proinsulin in the rat].
    Arzneimittel-Forschung, 1972, Volume: 22, Issue:11

    Topics: Animals; Chromatography, Gel; Electrophoresis, Disc; Glucose; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Islets of Langerhans; Leucine; Male; Proinsulin; Pyrimidines; Rats; Sulfonic Acids; Sulfonylurea Compounds; Tolbutamide; Tritium

1972
Metabolic aspects of the Beckwith-Wiedemann syndrome.
    The Journal of pediatrics, 1973, Volume: 82, Issue:2

    Topics: Abnormalities, Multiple; Adrenal Gland Diseases; Blood Glucose; Child, Preschool; Diazoxide; Epinephrine; Glucagon; Glucose; Glucose Tolerance Test; Growth Hormone; Hernia, Umbilical; Humans; Hydrocortisone; Hyperinsulinism; Hypoglycemia; Infant, Newborn; Infant, Newborn, Diseases; Insulin; Kidney Diseases; Leucine; Male; Tolbutamide; Tongue; Umbilicus

1973
Glucose, tolbutamide and leucine tolerances in hypoglycemia.
    Postgraduate medicine, 1973, Volume: 53, Issue:4

    Topics: Administration, Oral; Blood Glucose; Diabetes Complications; Diabetes Mellitus; Glucose Tolerance Test; Humans; Hypoglycemia; Injections, Intravenous; Insulin; Leucine; Time Factors; Tolbutamide

1973
Incorporation of leucine into protein by isolated fat cells--effects of agents which stimulate glucose metabolism and inhibit lipolysis.
    Biochemical pharmacology, 1973, Nov-01, Volume: 22, Issue:21

    Topics: Adenine Nucleotides; Adipose Tissue; Animals; Concanavalin A; Cysteine; Glucose; In Vitro Techniques; Insulin; Leucine; Lipid Metabolism; Nystatin; Ouabain; Polyamines; Propylamines; Protein Biosynthesis; Pyruvates; Rats; Spermidine; Swine; Tolbutamide; Tritium; Vitamin K

1973
[Hypoglycemia].
    Actualites de physiologie pathologique, 1973, Volume: 4

    Topics: Child; Dietary Carbohydrates; Epinephrine; Gastrointestinal Hormones; Glucagon; Gluconeogenesis; Glucose; Humans; Hyperglycemia; Hyperinsulinism; Hypoglycemia; Hypoglycemic Agents; Insulin; Intestinal Absorption; Leucine; Liver Glycogen; Pancreatic Neoplasms; Thyroid Hormones; Tolbutamide

1973
Perifusion of pancreas fragments. A system for the study of dynamic aspects of insulin secretion.
    Diabetes, 1974, Volume: 23, Issue:6

    Topics: Alanine; Animals; Arginine; Culture Media; Fructose; Galactose; Glucose; Glycolysis; Hydrogen-Ion Concentration; In Vitro Techniques; Insulin; Insulin Antibodies; Insulin Secretion; Iodine Radioisotopes; Leucine; Male; Mannose; Methods; Pancreas; Perfusion; Rats; Ribose; Time Factors; Tolbutamide; Xylitol

1974
Plasma insulin in patients with myotonic dystrophy and their relatives.
    Medicine, 1974, Volume: 53, Issue:4

    Topics: Adolescent; Adult; Aged; Amino Acids; Antigens; Arginine; Child; Child, Preschool; Electromyography; Female; Glucagon; Glucose Tolerance Test; Heterozygote; Humans; Hyperinsulinism; Insulin; Leucine; Male; Middle Aged; Muscles; Myotonic Dystrophy; Tolbutamide

1974
Dynamics of insulin secretion in myotonic dystrophy.
    The Journal of clinical endocrinology and metabolism, 1968, Volume: 28, Issue:7

    Topics: Adult; Blood Glucose; Epinephrine; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Middle Aged; Myotonic Dystrophy; Tolbutamide

1968
Electrical activity in pancreatic islet cells.
    Nature, 1968, Jul-27, Volume: 219, Issue:5152

    Topics: Action Potentials; Animals; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Membrane Potentials; Mice; Tolbutamide

1968
Effects of amino acids on insulin release from excised rabbit pancreas.
    Endocrinology, 1969, Volume: 84, Issue:4

    Topics: Amino Acids; Animals; Arginine; Epinephrine; Glucose; Histidine; In Vitro Techniques; Insulin; Insulin Antagonists; Insulin Secretion; Islets of Langerhans; Leucine; Lysine; Rabbits; Stimulation, Chemical; Tolbutamide

1969
A-cell deficiency and B-cell hyperplasia of Langerhans' islet as a cause of leucine sensitive hypoglycemia.
    Endokrinologie, 1968, Volume: 53, Issue:3

    Topics: Blood Glucose; Diazoxide; Epinephrine; Glucose Tolerance Test; Humans; Hyperplasia; Hypoglycemia; Infant; Insulin; Islets of Langerhans; Leucine; Male; Pancreatectomy; Pancreatic Diseases; Seizures; Tolbutamide

1968
[Effect of blood sugar decreasing sulfonylureas on the in vitro metabolism of glucose and amino acids in the beta-cells of the pancreas in mice].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:8

    Topics: Alanine; Amino Acids; Animals; Arginine; Carbon Isotopes; Depression, Chemical; Female; Glucose; Hyperglycemia; Hypoglycemic Agents; In Vitro Techniques; Insulin; Islets of Langerhans; Leucine; Male; Mice; Obesity; Oxidation-Reduction; Oxygen Consumption; Pancreas; Stimulation, Chemical; Tolbutamide; Urea; Valine

1969
Insulin biosynthesis: effects of carbohydrates and related compounds.
    Canadian journal of physiology and pharmacology, 1969, Volume: 47, Issue:9

    Topics: Animals; Fructose; Fumarates; Globulins; Glucose; Glutamates; Hexoses; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Mannose; Protein Binding; Pyruvates; Rats; Ribose; Tolbutamide; Tritium; Xylitol

1969
The role of calcium and magnesium in insulin secretion from rabbit pancreas studied in vitro.
    Diabetologia, 1967, Volume: 3, Issue:1

    Topics: Animals; Calcium; Culture Media; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Magnesium; Rabbits; Tolbutamide

1967
[Regulation of insulin release in perifused pancreatic tissue].
    Acta diabetologica latina, 1969, Volume: 6 Suppl 1

    Topics: Amino Acids; Animals; Aprotinin; Arginine; Freezing; Glucagon; Glucose; Hypoglycemic Agents; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Pancreas; Perfusion; Rats; Sulfonamides; Tolbutamide

1969
The pancreatic islet of infants with severe hypoglycemia.
    Archives of pathology, 1970, Volume: 89, Issue:3

    Topics: Blood Glucose; Epinephrine; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Glucose Tolerance Test; Growth Hormone; Humans; Hyperplasia; Hypertrophy; Hypoglycemia; Infant; Infant, Newborn; Insulin; Islets of Langerhans; Leucine; Microscopy, Electron; Radioimmunoassay; Time Factors; Tolbutamide

1970
The effect of glucose on insulin biosynthesis by isolated islets of Langerhans of the rat.
    Biochimica et biophysica acta, 1970, Volume: 208, Issue:3

    Topics: Animals; Ascites; Carbon Isotopes; Chromatography, Gel; Cycloheximide; Electrophoresis; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Liver; Male; Metabolism; Mice; Phenylalanine; Protein Biosynthesis; Tolbutamide

1970
In vitro effect of various hypoglycemic agents on the hepatic and pancreatic protein synthesis in the rat.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1971, Volume: 3, Issue:5

    Topics: Animals; Cell-Free System; Depression, Chemical; Ethers; Female; Glyburide; Hypoglycemic Agents; Leucine; Liver; Male; Metabolism; Pancreas; Protein Biosynthesis; Pyrimidines; Rats; Rats, Inbred Strains; Sulfonylurea Compounds; Terpenes; Tolbutamide; Tritium

1971
Hypoglycemic action of 2-aminonorbornane-2-carboxylic acid in the rat.
    Biochemical and biophysical research communications, 1971, Jul-02, Volume: 44, Issue:1

    Topics: Amino Acids; Amino Acids, Cyclic; Animals; Binding Sites; Blood Glucose; Drug Synergism; Hypoglycemia; Insulin; Insulin Secretion; Kinetics; Leucine; Male; Rats; Stereoisomerism; Structure-Activity Relationship; Terpenes; Tolbutamide

1971
Failure of leucine, arginine, and epinephrine to alter plasma insulin levels in vitro.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1971, Volume: 3, Issue:2

    Topics: Animals; Antigen-Antibody Reactions; Arginine; Depression, Chemical; Epinephrine; Guinea Pigs; Humans; Insulin; Insulin Antibodies; Iodine Isotopes; Leucine; Radioimmunoassay; Stimulation, Chemical; Swine; Tolbutamide

1971
Study on the formation and release of insulin with special reference to electron microscopic observation.
    Archivum histologicum Japonicum = Nihon soshikigaku kiroku, 1966, Volume: 27, Issue:1

    Topics: Animals; Blood Glucose; Female; Glucose; Insulin; Insulin Antibodies; Islets of Langerhans; Leucine; Male; Microscopy, Electron; Rabbits; Tolbutamide

1966
[The effect of L-leucine on blood sugar and serum phosphate in rabbits].
    Acta biologica et medica Germanica, 1969, Volume: 22, Issue:3

    Topics: Animals; Blood Glucose; Carbutamide; Fasting; Female; Injections, Intravenous; Insulin; Leucine; Male; Phosphates; Rabbits; Tolbutamide

1969
Studies in spiny mice (Acomys cahirinus): metabolic state and pancreatic insulin release in vitro.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1969, Volume: 1, Issue:2

    Topics: Age Factors; Animals; Antigens; Arginine; Blood Glucose; Caffeine; Calcium; Diabetes Mellitus; Glucagon; Glycosuria; Hyperglycemia; In Vitro Techniques; Insulin; Insulin Secretion; Leucine; Mice; Mice, Inbred Strains; Obesity; Pancreas; Tolbutamide

1969
Studies on the radioimmunological determination of blood insulin by means of 125-I-insulin of high specific activity.
    Polish medical journal, 1970, Volume: 9, Issue:6

    Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Animals; Blood Glucose; Diabetes Mellitus, Type 1; Fasting; Female; Glucagon; Glucose; Humans; Infant; Insulin; Iodine Isotopes; Leucine; Methods; Obesity; Radioimmunoassay; Swine; Tolbutamide

1970
The effects of epinephrine, amino acids and albumin on the measurement of insulin by radioimmunoassay.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1970, Volume: 2, Issue:3

    Topics: Animals; Antigen-Antibody Reactions; Antigens; Arginine; Binding Sites; Chemical Phenomena; Chemistry; Diazoxide; Epinephrine; Evaluation Studies as Topic; Glucose; Glucose Tolerance Test; Guinea Pigs; Humans; Immune Sera; Insulin; Insulin Antibodies; Iodine Isotopes; Leucine; Methods; Protein Binding; Radioimmunoassay; Serum Albumin; Swine; Tolbutamide

1970
[Diagnostic tests in hypoglycemic syndromes].
    Folia endocrinologica, 1970, Volume: 23, Issue:2

    Topics: Blood Glucose; Diagnosis, Differential; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Leucine; Tolbutamide

1970
Insulin secretion studied in the perfused rat pancreas. I. Effect of tolbutamide, leucine and arginine; their interaction with diazoxide, and relation to glucose.
    Diabetes, 1971, Volume: 20, Issue:7

    Topics: Animals; Arginine; Buffers; Diazoxide; Glucose; Insulin; Insulin Secretion; Leucine; Male; Pancreas; Perfusion; Radioimmunoassay; Rats; Stimulation, Chemical; Tolbutamide

1971
[Cerebral convulsion as symptom in spontaneous hypoglycemia in childhood].
    Medizinische Klinik, 1971, Jun-23, Volume: 66, Issue:30

    Topics: Acetone; Adrenal Cortex Hormones; Blood Glucose; Child, Preschool; Diagnosis, Differential; Diet Therapy; Dietary Fats; Electroencephalography; Epinephrine; Female; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Infant; Insulin; Leucine; Male; Prognosis; Seizures; Tolbutamide

1971
[Management of functional hypoglycemia in the adult].
    Folia clinica internacional, 1967, Volume: 17, Issue:10

    Topics: Adult; Fructose; Galactosemias; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Leucine; Tolbutamide

1967
[Functional exploration of insulin secretion in sponteaneous hypoglycemia].
    Acta isotopica, 1967, Dec-15, Volume: 7, Issue:1

    Topics: Adenoma; Arginine; Glucagon; Glucose; Humans; Hyperinsulinism; Hypoglycemia; Insulin; Insulin Secretion; Leucine; Pancreas; Pancreatic Neoplasms; Tolbutamide

1967
Tolbutamide and the incorporation of [3H]leucine into insulin in vitro.
    The Journal of endocrinology, 1967, Volume: 39, Issue:3

    Topics: Animals; Humans; In Vitro Techniques; Insulin; Leucine; Pancreas; Rabbits; Secretory Rate; Tolbutamide; Tritium

1967
The role of sodium and potassium in insulin secretion from rabbit pancreas.
    The Journal of physiology, 1968, Volume: 194, Issue:3

    Topics: Animals; Atropine; Biological Transport, Active; Choline; Glucagon; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Leucine; Lithium; Ouabain; Pancreas; Potassium; Rabbits; Sodium; Tolbutamide

1968
Effect of in vivo administration of various oral hypoglycemic agents on hepatic protein synthesis.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1968, Volume: 127, Issue:2

    Topics: Animals; Carbon Isotopes; Female; Leucine; Liver; Microsomes; Phenformin; Protein Biosynthesis; Rats; Tolbutamide

1968
Tolbutamide tolerance test and plasma-insulin response in hypoglycemia.
    The Journal of pediatrics, 1968, Volume: 72, Issue:4

    Topics: Amino Acid Metabolism, Inborn Errors; Blood Glucose; Child; Diagnosis, Differential; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Leucine; Tolbutamide

1968
Response of hepatic alpha-glycerophosphate to changes in hepatic glucose formation.
    Metabolism: clinical and experimental, 1968, Volume: 17, Issue:9

    Topics: Animals; Blood Glucose; Dogs; Fasting; Glucose; Glycerophosphates; Glycolysis; Leucine; Liver; Liver Extracts; Male; Rats; Tolbutamide

1968
The inhibition in vitro of hepatic protein biosynthesis by various oral hypoglycemic agents--site of action.
    Biochemical pharmacology, 1969, Volume: 18, Issue:3

    Topics: Animals; Carbon Isotopes; Chlorpropamide; Female; Hypoglycemic Agents; In Vitro Techniques; Leucine; Liver; Lysine; Microsomes; Phenformin; Phenylalanine; Protein Biosynthesis; Rats; RNA, Transfer; Time Factors; Tolbutamide

1969
Behavior in the rat of a transport-specific, bicyclic amino acid. Hypoglycemic action.
    The Journal of biological chemistry, 1969, Mar-25, Volume: 244, Issue:6

    Topics: Adrenal Glands; Adrenalectomy; Amino Acids; Animals; Blood Glucose; Bridged-Ring Compounds; Carbon Isotopes; Diaphragm; Drug Synergism; Leucine; Male; Pancreas; Phenylalanine; Rats; Stereoisomerism; Tolbutamide

1969
Diazoxide in the management of hypoglycemia in infancy and childhood.
    American journal of diseases of children (1960), 1969, Volume: 117, Issue:4

    Topics: Blood Glucose; Child; Child, Preschool; Diazoxide; Female; Glucose; Glucose Tolerance Test; Growth Hormone; Humans; Hypoglycemia; Infant; Insulin; Insulin Secretion; Leucine; Male; Tolbutamide

1969
The response of infants of diabetic women to tolbutamide and leucine at birth, and to glucose and tolbutamide at 2 years of age.
    Pediatrics, 1969, Volume: 43, Issue:4

    Topics: Blood Glucose; Child, Preschool; Diabetes Mellitus; Female; Glucose Tolerance Test; Humans; Infant, Newborn; Injections, Intravenous; Insulin; Insulin Secretion; Leucine; Male; Prediabetic State; Pregnancy; Pregnancy in Diabetics; Tolbutamide

1969
[Idiopathic hypoglycemia in the child].
    Deutsche medizinische Wochenschrift (1946), 1969, Mar-28, Volume: 94, Issue:13

    Topics: Age Factors; Child; Child, Preschool; Epinephrine; Fatty Acids, Nonesterified; Female; Glucagon; Glucose Tolerance Test; Growth Hormone; Humans; Hypoglycemia; Infant; Infant, Newborn; Insulin; Leucine; Male; Tolbutamide

1969
The interaction of various inhibitors and stimuli of insulin release studied with rabbit pancreas in vitro.
    The Biochemical journal, 1969, Volume: 113, Issue:3

    Topics: Animals; Barium; Diazoxide; Dibucaine; Dinitrophenols; Epinephrine; Glucose; Heptoses; Hypoxia; In Vitro Techniques; Insulin; Insulin Secretion; Leucine; Ouabain; Pancreas; Potassium; Rabbits; Tetrodotoxin; Tolbutamide

1969
Spontaneous hypoglycaemia and sarcoma. A case report.
    Acta endocrinologica, 1965, Volume: 50, Issue:2

    Topics: Blood; Fibrosarcoma; Glucagon; Glucose Tolerance Test; Granulosa Cell Tumor; Humans; Hypoglycemia; Insulin; Leucine; Male; Middle Aged; Tolbutamide

1965
L-leucine in secondary sulfonylurea failure.
    Diabetes, 1966, Volume: 15, Issue:3

    Topics: Aged; Chlorpropamide; Diabetes Mellitus; Female; Humans; In Vitro Techniques; Leucine; Male; Middle Aged; Tolbutamide

1966
Hypoglycemia due to intrapancreatic infusion of leucine.
    Diabetes, 1966, Volume: 15, Issue:8

    Topics: Animals; Dogs; Hypoglycemia; Insulin; Leucine; Liver; Pancreas; Tolbutamide

1966
The in vitro effect of two oral hypoglycemic agents on hepatic protein synthesis.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1966, Volume: 122, Issue:3

    Topics: Animals; Biguanides; Carbon Dioxide; Glucose; Hypoglycemic Agents; In Vitro Techniques; Leucine; Liver; Protein Biosynthesis; Rats; Tolbutamide

1966
Effect of insulin, chlorpropamide and tolbutamide on the metabolism of branched chain amino acids.
    Annales medicinae experimentalis et biologiae Fenniae, 1966, Volume: 44

    Topics: Animals; Chlorpropamide; In Vitro Techniques; Insulin; Isoleucine; Leucine; Rabbits; Rats; Tolbutamide; Valine

1966
Cortisol production rate. VI. Hypoglycemia in the neonatal and postneonatal period, and in association with dwarfism.
    The Journal of pediatrics, 1967, Volume: 70, Issue:1

    Topics: 17-Ketosteroids; Birth Weight; Child; Child, Preschool; Dwarfism; Epinephrine; Female; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Infant; Infant, Newborn; Insulin; Leucine; Male; Pituitary Function Tests; Tolbutamide

1967
Clinical alcohol hypoglycemia.
    Annals of internal medicine, 1967, Volume: 66, Issue:5

    Topics: Aged; Alcoholic Intoxication; Alcoholism; Blood Glucose; Ethanol; Fasting; Female; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Injections, Intravenous; Leucine; Male; Tolbutamide

1967
Secondary failure to sulphonylureas in the treatment of diabetes.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1967, May-06, Volume: 41, Issue:18

    Topics: Carbutamide; Chlorpropamide; Diabetes Mellitus; Drug Tolerance; Humans; Leucine; Tolbutamide

1967
The effects of three oral hypoglycemic agents on the incorporation of leucine-C14 into protein by liver microsomes of normal and alloxan-diabetic rats.
    Life sciences, 1967, Jan-15, Volume: 6, Issue:2

    Topics: Animals; Biguanides; Carbon Isotopes; Chlorpropamide; Diabetes Mellitus, Experimental; Female; Leucine; Liver; Microsomes; Proteins; Rats; Tolbutamide

1967
Metabolic effects of hypoglycemic sulfonylureas. I. In vitro effect of sulfonylureas on leucine incorporation and metabolism and on respiration of rat tissues.
    Biochemical pharmacology, 1967, Volume: 16, Issue:12

    Topics: Adipose Tissue; Animals; Carbon Isotopes; Carbutamide; Chlorpropamide; Diaphragm; Hypoglycemic Agents; In Vitro Techniques; Kidney; Leucine; Liver; Male; Muscle Proteins; Muscles; Oxygen Consumption; Protein Biosynthesis; Rats; Tolbutamide

1967
Evidence that glucose "marks" beta cells resulting in preferential release of newly synthesized insulin.
    Science (New York, N.Y.), 1982, Oct-01, Volume: 218, Issue:4567

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Leucine; Potassium; Tolbutamide

1982
Thiol-dependent and non-thiol-dependent stimulations of insulin release.
    Diabetes, 1984, Volume: 33, Issue:3

    Topics: Animals; Bucladesine; Calcimycin; Calcium; Diamide; Dose-Response Relationship, Drug; Female; Glucose; Glutathione; Glyburide; Glyceraldehyde; Insulin; Insulin Secretion; Islets of Langerhans; Isoproterenol; Leucine; Male; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Tolbutamide

1984
Chloride modulation of insulin release, 86Rb+ efflux, and 45Ca2+ fluxes in rat islets stimulated by various secretagogues.
    Diabetes, 1983, Volume: 32, Issue:5

    Topics: Animals; Arginine; Calcium; Chlorides; Exocytosis; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Rats; Rats, Inbred Strains; Rubidium; Theophylline; Tolbutamide

1983
Glucose insensitivity and amino-acid hypersensitivity of insulin release in rats with non-insulin-dependent diabetes. A study with the perfused pancreas.
    Diabetes, 1983, Volume: 32, Issue:5

    Topics: Acetylcholine; Amino Acids; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Glucose; Glyceraldehyde; Insulin; Insulin Secretion; Islets of Langerhans; Isoproterenol; Keto Acids; Leucine; Mannose; Rats; Rats, Inbred Strains; Theophylline; Tolbutamide

1983
Effects of D-mannoheptulose on blood glucose and alloxan sensitivity in mice.
    Acta endocrinologica, 1980, Volume: 94, Issue:1

    Topics: Alloxan; Animals; B-Lymphocytes; Blood Glucose; Diabetes Mellitus, Experimental; Female; Heptoses; Hydroxymercuribenzoates; Insulin; Leucine; Liver Glycogen; Male; Mannoheptulose; Mice; Mice, Inbred C57BL; Starvation; Tolbutamide

1980
cAMP-enhancing agents "permit" stimulus-secretion coupling in canine pancreatic islet beta-cells.
    The Journal of membrane biology, 1994, Volume: 138, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Membrane; Colforsin; Cyclic AMP; Dogs; Exocytosis; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Membrane Potentials; Thionucleotides; Tolbutamide

1994
Alterations of insulin response to different beta cell secretagogues and pancreatic vascular resistance induced by N omega-nitro-L-arginine methyl ester.
    British journal of pharmacology, 1995, Volume: 116, Issue:3

    Topics: Analysis of Variance; Animals; Arginine; Drug Interactions; Glucose; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Pancreas; Potassium Chloride; Rats; Rats, Wistar; Stereoisomerism; Tolbutamide; Vascular Resistance; Vasoconstriction; Vasodilator Agents

1995
Secretagogue-induced [Ca2+]i changes in single rat pancreatic islets and correlation with simultaneously measured insulin release.
    Journal of molecular endocrinology, 1995, Volume: 15, Issue:2

    Topics: Animals; Calcium; Carbachol; Cells, Cultured; Cytosol; Diazoxide; Fluorescent Dyes; Fura-2; Glucose; Glutamine; Indoles; Inulin; Islets of Langerhans; Kinetics; Leucine; Male; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Time Factors; Tolbutamide

1995
The role of the CYP2C9-Leu359 allelic variant in the tolbutamide polymorphism.
    Pharmacogenetics, 1996, Volume: 6, Issue:4

    Topics: Alleles; Aryl Hydrocarbon Hydroxylases; Asian People; Black People; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Heterozygote; Homozygote; Humans; Leucine; Recombinant Proteins; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Tolbutamide; White People

1996
Optimization of culture conditions for the preservation of monkey pancreatic islets in culture.
    Pancreas, 1999, Volume: 19, Issue:1

    Topics: Animals; Arginine; Cell Culture Techniques; Cell Separation; Cell Survival; Cells, Cultured; Female; Glucose; Insulin; Islets of Langerhans; Leucine; Macaca radiata; Male; Tolbutamide

1999
Amyloid fibril formation is progressive and correlates with beta-cell secretion in transgenic mouse isolated islets.
    Diabetologia, 1999, Volume: 42, Issue:10

    Topics: Amyloid; Animals; Cell Survival; Cells, Cultured; Culture Media, Conditioned; Dose-Response Relationship, Drug; Extracellular Space; Female; Glucose; Glutamine; Humans; Hypoglycemic Agents; Insulin; Islet Amyloid Polypeptide; Islets of Langerhans; Keto Acids; Leucine; Male; Mice; Mice, Transgenic; Time Factors; Tolbutamide

1999
Leucine prolongation of tolbutamide-induced hypoglycemia.
    Metabolism: clinical and experimental, 1962, Volume: 11

    Topics: Humans; Hypoglycemia; Hypoglycemic Agents; Leucine; Pancreatic Diseases; Phosphates; Potassium; Tolbutamide

1962
Acute tolbutamide and leucine effects in diabetes mellitus.
    Metabolism: clinical and experimental, 1962, Volume: 11

    Topics: Diabetes Mellitus; Hyperglycemia; Hypoglycemia; Leucine; Pancreatic Diseases; Phosphates; Potassium; Tolbutamide

1962
FUNCTIONING PANCREATIC ISLET CELL ADENOMA. WITH LEUCINE-INDUCED HYPOGLYCEMIA.
    Archives of internal medicine, 1963, Volume: 112

    Topics: Adenoma, Islet Cell; Fasting; Humans; Hypoglycemia; Insulin; Leucine; Pancreatic Neoplasms; Pathology; Surgical Procedures, Operative; Tolbutamide; Toxicology

1963
STUDIES ON THE MECHANISM OF LEUCINE-INDUCED HYPOGLYCEMIA.
    Metabolism: clinical and experimental, 1963, Volume: 12

    Topics: Carbohydrate Metabolism; Diaphragm; Fasting; Glucagon; Glycogen; Hypoglycemia; Insulin; Islets of Langerhans; Leucine; Liver Glycogen; Muscles; Pharmacology; Rats; Research; Tolbutamide

1963
THE EFFECT OF ANABOLIC STEROIDS ON BLOOD SUGAR AND PLASMA INSULIN LEVELS IN MAN.
    Metabolism: clinical and experimental, 1963, Volume: 12

    Topics: Adolescent; Anabolic Agents; Blood Chemical Analysis; Blood Glucose; Diabetes Mellitus; Geriatrics; Insulin; Leucine; Nandrolone; Pharmacology; Steroids; Tolbutamide

1963
HYPOGLYCEMIA, GROWTH RETARDATION, AND PROBABLE ISOLATED GROWTH HORMONE DEFICIENCY IN A 1-YEAR-OLD CHILD.
    The Journal of pediatrics, 1963, Volume: 63

    Topics: Carbohydrate Metabolism; Child; Deficiency Diseases; Dwarfism, Pituitary; Growth; Growth Hormone; Human Growth Hormone; Humans; Hypoglycemia; Infant; Leucine; Tolbutamide

1963
EXTRAPANCREATIC INSULIN-SECRETING TUMOR.
    The New England journal of medicine, 1964, Feb-13, Volume: 270

    Topics: Fibrosarcoma; Geriatrics; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Leucine; Pathology; Retroperitoneal Neoplasms; Surgical Procedures, Operative; Tolbutamide

1964
STUDIES OF CARBOHYDRATE METABOLISM IN THE NEWBORN INFANT. VII. TESTS OF CARBOHYDRATE TOLERANCE IN PREMATURE INFANTS.
    Pediatrics, 1963, Volume: 32

    Topics: Blood Glucose; Carbohydrate Metabolism; Drug Tolerance; Epinephrine; Fructose; Galactose; Glucagon; Glucose Tolerance Test; Humans; Infant; Infant, Newborn; Infant, Premature; Leucine; Tolbutamide

1963
LEUCINE-INDUCED HYPOGLYCAEMIA AND ORAL HYPOGLYCAEMIC DRUGS.
    British medical journal, 1964, Apr-04, Volume: 1, Issue:5387

    Topics: Autoradiography; Carbon Isotopes; Chromatography; Diaphragm; Hypoglycemia; Hypoglycemic Agents; Insulin; Leucine; Pharmacology; Phenformin; Proteins; Rats; Research; Tolbutamide

1964
[HYPOGLYCEMIC REACTION TO LEUCINE, VALINE AND PHENYLALANINE IN A CASE OF DIFFUSE HYPERPLASIA OF THE BETA CELLS].
    Folia endocrinologica, 1963, Volume: 16

    Topics: Glucose Tolerance Test; Humans; Hyperinsulinism; Hyperplasia; Hypoglycemia; Hypoglycemic Agents; Insulin-Secreting Cells; Islands; Islets of Langerhans; Leucine; Pathology; Pharmacology; Phenylalanine; Tolbutamide; Valine

1963
LEUCINE-SENSITIVE HYPOGLYCEMIA.
    Proceedings of the Royal Society of Medicine, 1964, Volume: 57

    Topics: Glucose Tolerance Test; Humans; Hypoglycemia; Infant; Leucine; Metabolism; Methylprednisolone; Seizures; Tolbutamide

1964
SYMPTOMATIC NEONATAL HYPOGLYCEMIA. STUDIES OF CARBOHYDRATE METABOLISM IN THE NEWBORN INFANT. VIII.
    Pediatrics, 1964, Volume: 33

    Topics: Adolescent; Black People; Blood Chemical Analysis; Carbohydrate Metabolism; Central Nervous System Diseases; Child; Diseases in Twins; Epinephrine; Female; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Infant; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature, Diseases; Leucine; Liver Glycogen; Neurologic Manifestations; Polycythemia; Pre-Eclampsia; Pregnancy; Tolbutamide

1964
FUNCTIONING ISLET CELL ADENOMA.
    JAMA, 1964, Jun-01, Volume: 188

    Topics: Adenoma, Islet Cell; Cerebrovascular Disorders; Diagnosis, Differential; Geriatrics; Humans; Hyperinsulinism; Leucine; Pancreatic Neoplasms; Tolbutamide

1964
SPONTANEOUS HYPOGLYCEMIA: DIAGNOSTIC CONSIDERATIONS AND MANAGEMENT.
    Arizona medicine, 1964, Volume: 21

    Topics: Adenoma, Islet Cell; Diabetes Mellitus; Diagnosis, Differential; Humans; Hypoglycemia; Leucine; Malingering; Neoplasm Metastasis; Pancreatic Neoplasms; Surgical Procedures, Operative; Tolbutamide

1964
[STUDIES ON ORAL TOLBUTAMIDE TEST].
    Naika hokan. Japanese archives of internal medicine, 1964, Volume: 11

    Topics: Blood Glucose; Carbutamide; Cystine; Diabetes Mellitus; Diagnosis; Gastric Juice; Hypoglycemia; Leucine; Liver Cirrhosis; Nephritis; Pancreatic Diseases; Pharmacology; Tolbutamide

1964
PLASMA INSULIN IN ORGANIC HYPERINSULINISM: COMPARATIVE EFFECTS OF TOLBUTAMIDE, LEUCINE AND GLUCOSE.
    The Journal of clinical endocrinology and metabolism, 1964, Volume: 24

    Topics: Adenoma, Islet Cell; Blood; Blood Chemical Analysis; Blood Glucose; Glucagon; Glucose; Humans; Hyperglycemia; Hyperinsulinism; Hypoglycemia; Insulin; Leucine; Pancreatic Neoplasms; Pharmacology; Surgical Procedures, Operative; Tolbutamide

1964
CUSHING'S SYNDROME WITH HYPOGLYCEMIA CAUSED BY ADRENOCORTICAL CARCINOMA.
    The Journal of clinical endocrinology and metabolism, 1965, Volume: 25

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Neoplasms; Adrenocortical Carcinoma; Aldosterone; Anabolic Agents; Androsterone; Cushing Syndrome; Dexamethasone; Etiocholanolone; Humans; Hydrocortisone; Hypoglycemia; Leucine; Manganese; Pathology; Steroids; Tolbutamide; Urine

1965
LIPOATROPHIC DIABETES. I. STUDIES CONCERNING ENDOCRINE FUNCTION AND CARBOHYDRATE METABOLISM.
    American journal of diseases of children (1960), 1965, Volume: 109

    Topics: Adolescent; Carbohydrate Metabolism; Diabetes Mellitus, Lipoatrophic; Diabetes Mellitus, Type 1; Drug Tolerance; Epinephrine; Fatty Acids; Glucagon; Glucose Tolerance Test; Hepatomegaly; Humans; Infant; Insulin; Insulin Resistance; L-Lactate Dehydrogenase; Leucine; Lipids; Lipodystrophy; Liver; Liver Cirrhosis; Liver Function Tests; Metyrapone; Pharmacology; Pituitary-Adrenal Function Tests; Radiography; Tolbutamide; Transaminases; Urine

1965
EVIDENCE FAVORING THE SARCOMATOUS ORIGIN OF AN INSULIN-LIKE SUBSTANCE IN A CASE OF FIBROSARCOMA WITH HYPOGLYCEMIA.
    The American journal of medicine, 1965, Volume: 38

    Topics: Blood Glucose; Calcium Isotopes; Chemical Phenomena; Chemistry; Epinephrine; Fibrosarcoma; Glucagon; Glucose Tolerance Test; Growth Hormone; Human Growth Hormone; Humans; Hypoglycemia; Insulin; Leucine; Liver Neoplasms; Pathology; Prolactin; Radioisotopes; Radionuclide Imaging; Tolbutamide

1965
Clinical features and insulin regulation in infants with a syndrome of prolonged neonatal hyperinsulinism.
    The Journal of pediatrics, 2006, Volume: 148, Issue:2

    Topics: Antihypertensive Agents; Calcium; Case-Control Studies; Diazoxide; Enteral Nutrition; Fasting; Female; Glucose; Humans; Hyperinsulinism; Hypoglycemia; Hypoglycemic Agents; Infant; Infant, Newborn; Infusions, Intravenous; Insulin; Insulin Secretion; Leucine; Male; Prospective Studies; Risk Factors; Sweetening Agents; Tolbutamide

2006