Compounds > tolbutamide

Page last updated: 2024-08-16

tolbutamide and leptin

tolbutamide has been researched along with leptin in 12 studies

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (41.67)	18.2507
2000's	6 (50.00)	29.6817
2010's	1 (8.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Klein, S; Landt, M; Segal, KR	1
Ashford, ML; Groppi, VE; Logan, SD; Smith, MA; Spanswick, D	1
Ashford, ML; Harvey, J; Herson, PS; McKenna, F; Spanswick, D	1
Ashford, ML; Harvey, J	1
Kirchgessner, AL; Liu, M; Seino, S	1
Ashford, ML; Mirshamsi, S; Routh, VH; Smith, MA; Spanswick, D	1
Chinookoswong, N; Davis, JR; Fernandez, V; Jazayeri, R; Levin, N; Saberi, M; Shi, ZQ; Singh, M; Smith, TL; Trevino, B; Wang, J; Yaspelkis, BB	1
Ashford, ML; Harvey, J; Irving, AJ; Rae, MG; Shanley, LJ	1
Higuchi, T; Honda, K; Murata, T; Narita, K	1
Benomar, Y; Crochet, S; Derouet, M; Rideau, N; Taouis, M	1
Alber, J; Ashcroft, FM; Balthasar, N; Belgardt, BF; Brüning, JC; Burdakov, D; Coppari, R; Fekete, C; Hampel, B; Horvath, TL; Janoschek, R; Koch, L; Krone, W; Ma, X; Mak, TW; Münzberg, H; Plum, L; Rother, E; Schwenk, F; Seibler, J; Shanabrough, M; Suzuki, A	1
Belgardt, BF; Brüning, JC; Dhillon, H; Elmquist, JK; Hampel, B; Hess, S; Horvath, TL; Husch, A; Klöckener, T; Kloppenburg, P; Lowell, BB; Paeger, L; Sohn, JW; Verhagen, LA; Williams, KW; Zigman, JM	1

Other Studies

12 other study(ies) available for tolbutamide and leptin

Article	Year
Relationship between insulin sensitivity and plasma leptin concentration in lean and obese men. Diabetes, 1996, Volume: 45, Issue:7 Topics: Adult; Analysis of Variance; Animals; Blood Glucose; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Leptin; Male; Models, Biological; Obesity; Probability; Proteins; Rodentia; Thinness; Tolbutamide	1996
Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels. Nature, 1997, Dec-04, Volume: 390, Issue:6659 Topics: Adenosine Triphosphate; Animals; Cell Membrane; Electrophysiology; Glucose; Hypoglycemic Agents; Hypothalamus; In Vitro Techniques; Leptin; Neurons; Obesity; Potassium Channels; Proteins; Rats; Rats, Sprague-Dawley; Rats, Zucker; Tolbutamide	1997
Leptin activates ATP-sensitive potassium channels in the rat insulin-secreting cell line, CRI-G1. The Journal of physiology, 1997, Nov-01, Volume: 504 ( Pt 3) Topics: Adenosine Triphosphate; Animals; Biotransformation; Cell Line; Electrophysiology; Hypoglycemic Agents; Insulin; Ion Channel Gating; Leptin; Membrane Potentials; Patch-Clamp Techniques; Potassium Channels; Proteins; Rats; Tolbutamide	1997
Insulin occludes leptin activation of ATP-sensitive K+ channels in rat CRI-G1 insulin secreting cells. The Journal of physiology, 1998, Sep-15, Volume: 511 ( Pt 3) Topics: Adenosine Triphosphate; Androstadienes; Animals; Binding, Competitive; Chromones; Diabetes Mellitus, Type 2; Diazoxide; Drug Interactions; Electric Conductivity; Enzyme Inhibitors; Hypoglycemic Agents; Insulin; Insulin Antagonists; Insulin Secretion; Insulin-Like Growth Factor I; Ion Channel Gating; Leptin; Membrane Potentials; Morpholines; Patch-Clamp Techniques; Potassium Channels; Proteins; Rats; Tolbutamide; Vasodilator Agents; Wortmannin	1998
Identification and characterization of glucoresponsive neurons in the enteric nervous system. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Dec-01, Volume: 19, Issue:23 Topics: Adenosine Triphosphate; Animals; Colon; Diazoxide; Electrophysiology; Enteric Nervous System; Gastrointestinal Motility; Glucose; Guinea Pigs; Leptin; Male; Myenteric Plexus; Neurons; Potassium Channels; Synaptic Transmission; Tolbutamide	1999
Insulin activates ATP-sensitive K+ channels in hypothalamic neurons of lean, but not obese rats. Nature neuroscience, 2000, Volume: 3, Issue:8 Topics: Adenosine Triphosphate; Animals; Arcuate Nucleus of Hypothalamus; Glucose; Hypothalamus; In Vitro Techniques; Insulin; Leptin; Membrane Potentials; Neurons; Obesity; Patch-Clamp Techniques; Phosphatidylinositol 3-Kinases; Potassium Channels; Rats; Rats, Zucker; Thinness; Tolbutamide	2000
Leptin administration improves skeletal muscle insulin responsiveness in diet-induced insulin-resistant rats. American journal of physiology. Endocrinology and metabolism, 2001, Volume: 280, Issue:1 Topics: 3-O-Methylglucose; Animals; Blood Glucose; Body Mass Index; Diet; Dietary Fats; Energy Intake; Glucose Clamp Technique; Glucose Tolerance Test; Glucose Transporter Type 4; Glycogen; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Leptin; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Rats; Rats, Wistar; Tolbutamide	2001
Leptin inhibits rat hippocampal neurons via activation of large conductance calcium-activated K+ channels. Nature neuroscience, 2002, Volume: 5, Issue:4 Topics: Animals; Calcium; Carrier Proteins; Cells, Cultured; Charybdotoxin; Hippocampus; Humans; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Leptin; Neurons; Patch-Clamp Techniques; Phosphatidylinositol 3-Kinases; Potassium Channels, Calcium-Activated; Rats; Receptors, Cell Surface; Receptors, Leptin; Tetraethylammonium; Tolbutamide	2002
Leptin affects the electrical activity of neurones in the hypothalamic supraoptic nucleus. Brain research bulletin, 2002, Mar-15, Volume: 57, Issue:5 Topics: Action Potentials; Animals; Carrier Proteins; Hypoglycemic Agents; Leptin; Male; Mutation; Neural Inhibition; Neurons; Oxytocin; Potassium Channels; Rats; Rats, Wistar; Rats, Zucker; Receptors, Cell Surface; Receptors, Leptin; Supraoptic Nucleus; Synaptic Transmission; Tolbutamide; Vasopressins	2002
Leptin fully suppresses acetylcholine-induced insulin secretion and is reversed by tolbutamide in isolated perfused chicken pancreas. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2003, Volume: 35, Issue:2 Topics: Acetylcholine; Animals; Base Sequence; Chickens; Cholinergic Antagonists; Diazoxide; DNA Primers; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Leptin; Perfusion; Receptors, Cell Surface; Receptors, Leptin; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Tolbutamide	2003
Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity. The Journal of clinical investigation, 2006, Volume: 116, Issue:7 Topics: Animals; Chromones; Diet; Eating; Female; Hypoglycemic Agents; Hypothalamus; Insulin; Leptin; Male; Membrane Potentials; Mice; Mice, Knockout; Morpholines; Neurons; Obesity; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Phosphoinositide-3 Kinase Inhibitors; Potassium Channels; Pro-Opiomelanocortin; PTEN Phosphohydrolase; Second Messenger Systems; Tolbutamide	2006
High-fat feeding promotes obesity via insulin receptor/PI3K-dependent inhibition of SF-1 VMH neurons. Nature neuroscience, 2011, Jun-05, Volume: 14, Issue:7 Topics: Action Potentials; Age Factors; Animals; Animals, Newborn; Blood Glucose; Body Weight; Calorimetry; Dietary Fats; Dose-Response Relationship, Drug; Eating; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation; Glucose Tolerance Test; Green Fluorescent Proteins; Hypoglycemic Agents; In Vitro Techniques; Injections, Intraventricular; Insulin; Leptin; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Obesity; Patch-Clamp Techniques; Phosphatidylinositol 3-Kinases; Receptor, Insulin; RNA, Messenger; Signal Transduction; Steroidogenic Factor 1; Time Factors; Tolbutamide; Ventromedial Hypothalamic Nucleus	2011