Page last updated: 2024-08-16

tolbutamide and lactic acid

tolbutamide has been researched along with lactic acid in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199011 (52.38)18.7374
1990's5 (23.81)18.2507
2000's3 (14.29)29.6817
2010's2 (9.52)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Best, L; Meats, JE; Tomlinson, S; Yates, AP1
Best, L; Lynch, AM; Meats, JE; Tomlinson, S; Tuersley, MD1
Berbil-Bautista, PR; Felíu, JE; Guijarro, C; López-Alarcón, L1
Patel, TB1
Schaffer, SW; Tan, BH; Wilson, GL1
Kramer, JH; Lampson, WG; Poole, CG; Schaffer, SW1
Blumberg, D; Brennan, MF; Burt, ME; Kher, U1
Boutelle, MG; Fellows, LK; Fillenz, M1
Hotta, N; Kobayashi, M; Koh, N; Komori, T; Sakakibara, F; Sakamoto, N1
Hashimoto, K; Kato, K; Miwa, I; Mizota, M; Murakami, N; Ohta, M; Okuda, J1
Bilinski, D; Carpentier, A; Giacca, A; Lewis, GF; Vranic, M1
Smoak, IW1
CAMMARN, MW; CRAIG, JW; DRUCKER, WR; MACKENZIE, MS; MILLER, M; WOODWARD, H1
BRUNETTI, P; GRIGNANI, F; SERPI, G1
FACCHINI, G1
DE MEUTTER, RC; SHREEVE, WW1
LOPEZ-QUIJADA, C; RODRIGUEZ- CANDELA, JL; RODRIGUEZ-CANDELA, R1
Fanning, KJ; Roberts, MS1
Burdakov, D; Fugger, L; González, JA; Jensen, LT1
Du, Q; Jia, L; Niu, J; Shi, Y; Xue, J; Zhang, D1

Other Studies

21 other study(ies) available for tolbutamide and lactic acid

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Effects of lactate on pancreatic islets. Lactate efflux as a possible determinant of islet-cell depolarization by glucose.
    The Biochemical journal, 1989, Apr-15, Volume: 259, Issue:2

    Topics: Animals; Calcium; Female; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Lactates; Lactic Acid; Rats; Rats, Inbred Strains; Tolbutamide

1989
Lactate alters plasma membrane potential, increases the concentration of cytosolic Ca2+ and stimulates the secretion of insulin by the hamster beta-cell line HIT-T15.
    Journal of molecular endocrinology, 1989, Volume: 3, Issue:2

    Topics: Acetates; Acetic Acid; Animals; Calcium; Cell Line; Cricetinae; Cytosol; Glucose; Hydrogen-Ion Concentration; Insulin; Insulin Secretion; Islets of Langerhans; Lactates; Lactic Acid; Membrane Potentials; Potassium; Tolbutamide; Valinomycin; Verapamil

1989
Glipentide and glucose metabolism in isolated rat hepatocytes.
    Biochemical pharmacology, 1988, Aug-15, Volume: 37, Issue:16

    Topics: Animals; Benzamides; Cyclopentanes; Fructosephosphates; Glucose; Lactates; Lactic Acid; Liver; Male; Phosphofructokinase-1; Rats; Rats, Inbred Strains; Sulfonylurea Compounds; Tolbutamide

1988
Effects of tolbutamide on gluconeogenesis and glycolysis in isolated perfused rat liver.
    The American journal of physiology, 1986, Volume: 250, Issue:1 Pt 1

    Topics: Animals; Carbon Dioxide; Gluconeogenesis; Glycolysis; Ketone Bodies; Lactates; Lactic Acid; Liver; Male; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Time Factors; Tolbutamide

1986
Effect of tolbutamide on myocardial metabolism and mechanical performance of the diabetic rat.
    Diabetes, 1984, Volume: 33, Issue:12

    Topics: Animals; Cardiac Output; Diabetes Mellitus, Experimental; Glucose; Heart; Kinetics; Lactates; Lactic Acid; Male; Myocardium; Oxygen Consumption; Rats; Rats, Inbred Strains; Time Factors; Tolbutamide

1984
Effect of tolbutamide on the mechanical function of the isolated rat heart subjected to global ischemia.
    Journal of molecular and cellular cardiology, 1981, Volume: 13, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Coronary Disease; Heart; Lactates; Lactic Acid; Male; Myocardium; Rats; Tolbutamide

1981
Tolbutamide inhibits gluconeogenesis in the tumor-influenced hepatocyte.
    The Journal of surgical research, 1993, Volume: 55, Issue:5

    Topics: Alanine; Animals; Gluconeogenesis; Lactates; Lactic Acid; Liver; Male; Methylcholanthrene; Neoplasm Transplantation; Rats; Rats, Inbred F344; Sarcoma, Experimental; Tolbutamide

1993
ATP-sensitive potassium channels and local energy demands in the rat hippocampus: an in vivo study.
    Journal of neurochemistry, 1993, Volume: 61, Issue:3

    Topics: Adenosine Triphosphate; Administration, Topical; Animals; Energy Metabolism; Glucose; Hippocampus; Lactates; Lactic Acid; Male; Physical Stimulation; Potassium Channels; Rats; Rats, Sprague-Dawley; Tail; Tolbutamide

1993
The inhibitory action of buformin, a biguanide on gluconeogenesis from alanine and its transport system in rat livers.
    Diabetes research and clinical practice, 1993, Volume: 19, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Alanine; Animals; Biological Transport, Active; Buformin; Cell Separation; Diabetes Mellitus, Experimental; Glucagon; Gluconeogenesis; Hydroxybutyrates; Lactates; Lactic Acid; Liver; Male; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Tolbutamide

1993
Acceleration of glycolysis in erythrocytes by the antidiabetic agent M16209.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:6

    Topics: Aldehyde Reductase; Animals; Benzofurans; Erythrocytes; Glucose; Glyceraldehyde; Glycolysis; Humans; Hydantoins; Hypoglycemic Agents; Imidazoles; Imidazolidines; In Vitro Techniques; Lactic Acid; Male; Phosphofructokinase-1; Rats; Rats, Wistar; Tolbutamide

1996
Counterregulatory response to hypoglycemia differs according to the insulin delivery route, but does not affect glucose production in normal humans.
    The Journal of clinical endocrinology and metabolism, 1999, Volume: 84, Issue:3

    Topics: Adult; Blood Glucose; C-Peptide; Fatty Acids, Nonesterified; Glucose; Hormones; Humans; Hyperinsulinism; Hypoglycemia; Hypoglycemic Agents; Injections, Intravenous; Insulin; Lactic Acid; Male; Portal Vein; Reference Values; Tolbutamide; Veins

1999
Tolbutamide alters glucose transport and metabolism in the embryonic mouse heart.
    Teratology, 2002, Volume: 65, Issue:1

    Topics: Animals; Culture Techniques; Deoxyglucose; Endoplasmic Reticulum Chaperone BiP; Female; Gene Expression; Glucose; Glucose Transporter Type 1; Glycolysis; Heart; Hexokinase; HSP70 Heat-Shock Proteins; Isotope Labeling; Lactic Acid; Male; Membrane Proteins; Mice; Monosaccharide Transport Proteins; RNA, Messenger; Teratogens; Tolbutamide

2002
Studies of the effect of intravenous tolbutamide on pyruvic and lactic acid concentrations in peripheral venous blood in normal and diabetic subjects, and on splanchnic metabolism of fructose and glucose.
    Annals of the New York Academy of Sciences, 1957, Jul-10, Volume: 71, Issue:1

    Topics: Blood Glucose; Diabetes Mellitus; Fructose; Glucose; Humans; Hypoglycemic Agents; Lactic Acid; Pyruvates; Tolbutamide

1957
[Effect of carbutamide and tolbutamide serum glucose, pyruvic acid, lactic acid and ketone bodies in oral glucose tolerance test].
    Minerva medica, 1958, Apr-21, Volume: 49, Issue:32

    Topics: Carbutamide; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Ketone Bodies; Lactic Acid; Pyruvates; Pyruvic Acid; Tolbutamide

1958
[Research on the blood pyruvic acid and lactic acid levels in diabetics treated with carbutamide and tolbutamide].
    Endocrinologia e scienza della costituzione, 1958, Volume: 25, Issue:1

    Topics: Carbutamide; Diabetes Mellitus; Humans; Hypoglycemic Agents; Lactic Acid; Pyruvates; Pyruvic Acid; Research; Tolbutamide

1958
Conversion of DL-lactate-2-C14 or -3-C14 or pyruvate-2-C14 to blood glucose in humans: effects of diabetes, insulin, tolbutamide, and glucose load.
    The Journal of clinical investigation, 1963, Volume: 42

    Topics: Blood Glucose; Diabetes Mellitus; Glucose; Humans; Insulin; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Tolbutamide

1963
Tolbutamide influence in vitro on glucoseuptake, glycogen and lactic acid by the epididymal fat of normal and hypophysectomized rats.
    Medicina experimentalis : International journal of experimental medicine, 1962, Volume: 6

    Topics: Adipose Tissue; Animals; Glucose; Glycogen; Glycogenolysis; In Vitro Techniques; Lactates; Lactic Acid; Rats; Tolbutamide

1962
Characterization of the physiological spaces and distribution of tolbutamide in the perfused rat pancreas.
    Pharmaceutical research, 2007, Volume: 24, Issue:3

    Topics: Algorithms; Animals; Carbon Radioisotopes; Duodenum; Erythrocytes; Extracellular Space; Glucose; Hydrogen-Ion Concentration; Hypoglycemic Agents; Insulin; Insulin Secretion; Lactic Acid; Male; Oxygen Consumption; Pancreas; Perfusion; Rats; Rats, Wistar; Technetium; Tissue Distribution; Tolbutamide; Tritium

2007
Metabolism-independent sugar sensing in central orexin neurons.
    Diabetes, 2008, Volume: 57, Issue:10

    Topics: Acetylglucosamine; Alloxan; Animals; Carbohydrates; Deoxyglucose; Energy Metabolism; Fructose; Galactose; Glucosamine; Green Fluorescent Proteins; Hypothalamic Area, Lateral; Intracellular Signaling Peptides and Proteins; Lactic Acid; Mannose; Membrane Potentials; Methylglucosides; Mice; Mice, Transgenic; Neurons; Neuropeptides; Orexins; Patch-Clamp Techniques; Tolbutamide

2008
Surface-modified PLGA nanoparticles with chitosan for oral delivery of tolbutamide.
    Colloids and surfaces. B, Biointerfaces, 2018, Jan-01, Volume: 161

    Topics: Administration, Oral; Animals; Blood Glucose; Cell Survival; Chitosan; Diabetes Mellitus, Experimental; Drug Liberation; Hep G2 Cells; Humans; Hypoglycemic Agents; Lactic Acid; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Sprague-Dawley; Surface Properties; Tolbutamide

2018