Page last updated: 2024-08-16

tolbutamide and hypericum

tolbutamide has been researched along with hypericum in 3 studies

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Gorski, JC; Hall, SD; Hamman, MA; Huang, SM; Lesko, LJ; Wang, Z	1
Arold, G; Bauer, S; Diefenbach, K; Donath, F; Friede, M; Henneicke-von Zepelin, HH; Maurer, A; Roots, I	1
Dostalek, M; Hadasova, E; Jurica, J; Linhart, I; Pistovcakova, J; Sulcová, A; Tomandl, J	1

Trials

2 trial(s) available for tolbutamide and hypericum

Article	Year
The effects of St John's wort (Hypericum perforatum) on human cytochrome P450 activity. Clinical pharmacology and therapeutics, 2001, Volume: 70, Issue:4 Topics: Administration, Oral; Adult; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Biological Availability; Caffeine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextromethorphan; Dietary Supplements; Drug Interactions; Enzyme Induction; Female; Humans; Hypericum; Injections, Intravenous; Isoenzymes; Male; Midazolam; Oxidoreductases, N-Demethylating; Plant Extracts; Tolbutamide	2001
No relevant interaction with alprazolam, caffeine, tolbutamide, and digoxin by treatment with a low-hyperforin St John's wort extract. Planta medica, 2005, Volume: 71, Issue:4 Topics: Adult; Alprazolam; Anti-Anxiety Agents; Area Under Curve; Caffeine; Cardiotonic Agents; Central Nervous System Stimulants; Digoxin; Double-Blind Method; Drug Interactions; Female; Humans; Hypericum; Hypoglycemic Agents; Male; Middle Aged; Phytotherapy; Plant Extracts; Tolbutamide; Treatment Outcome	2005

Article

Year

The effects of St John's wort (Hypericum perforatum) on human cytochrome P450 activity.

Clinical pharmacology and therapeutics, 2001, Volume: 70, Issue:4

Topics: Administration, Oral; Adult; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Biological Availability; Caffeine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextromethorphan; Dietary Supplements; Drug Interactions; Enzyme Induction; Female; Humans; Hypericum; Injections, Intravenous; Isoenzymes; Male; Midazolam; Oxidoreductases, N-Demethylating; Plant Extracts; Tolbutamide

2001

No relevant interaction with alprazolam, caffeine, tolbutamide, and digoxin by treatment with a low-hyperforin St John's wort extract.

Planta medica, 2005, Volume: 71, Issue:4

Topics: Adult; Alprazolam; Anti-Anxiety Agents; Area Under Curve; Caffeine; Cardiotonic Agents; Central Nervous System Stimulants; Digoxin; Double-Blind Method; Drug Interactions; Female; Humans; Hypericum; Hypoglycemic Agents; Male; Middle Aged; Phytotherapy; Plant Extracts; Tolbutamide; Treatment Outcome

2005

Other Studies

1 other study(ies) available for tolbutamide and hypericum

Article	Year
Effect of St John's wort (Hypericum perforatum) on cytochrome P-450 activity in perfused rat liver. Life sciences, 2005, Dec-05, Volume: 78, Issue:3 Topics: Animals; Antidepressive Agents; Area Under Curve; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextromethorphan; Herb-Drug Interactions; Hypericum; Injections, Intraperitoneal; Liver; Male; Midazolam; Perfusion; Plant Extracts; Rats; Rats, Wistar; Tolbutamide	2005

Article

Year

Effect of St John's wort (Hypericum perforatum) on cytochrome P-450 activity in perfused rat liver.

Life sciences, 2005, Dec-05, Volume: 78, Issue:3

Topics: Animals; Antidepressive Agents; Area Under Curve; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextromethorphan; Herb-Drug Interactions; Hypericum; Injections, Intraperitoneal; Liver; Male; Midazolam; Perfusion; Plant Extracts; Rats; Rats, Wistar; Tolbutamide

2005