Page last updated: 2024-08-16

tolbutamide and hydrochlorothiazide

tolbutamide has been researched along with hydrochlorothiazide in 36 studies

Research

Studies (36)

Timeframe	Studies, this research(%)	All Research%
pre-1990	19 (52.78)	18.7374
1990's	0 (0.00)	18.2507
2000's	7 (19.44)	29.6817
2010's	10 (27.78)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Anacardio, R; Aureli, L; Cesta, MC; Cruciani, G; De Simone, L; Moriconi, A	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Conradi, R; Lee, PH; Shanmugasundaram, V	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Gold, B; Mirvish, SS	1
Gossain, VV; Hagen, GA; Sugawara, M	1
Goodman, AD; Mahoney, JH	1
Foy, JM; Furman, BL	1
Creutzfeldt, W	1
Creutzfeldt, W; Scheler, F; Wigger, W	1
Sato, A	1
Nimmo, J; Prescott, LF	1
De la Revilla, L; Estella, F; García Torres, JA; Gutiérrez, J; Peña, JF; Rosales, G	1
Walther, M	1
Bergmann, F; Gutman, Y; Zerachia, A	1
Baun, DC; Walker, GC	1
Bronzini, A; Gatti, A; Scotti, G	1
HENTRICH, K	1
SCHWARTZ, W	1
LANGDON, RG; WOLFF, FW	1
GARELLA, S	1
BOSHELL, BR; CHAZAN, JA	1
PANDYA, KV	1

Reviews

2 review(s) available for tolbutamide and hydrochlorothiazide

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Current views on the mode of action of hypoglycemic sulfonamides]. Acta diabetologica latina, 1969, Volume: 6 Suppl 1 Topics: Amino Acids; Animals; Blood Glucose; Chlorpropamide; Diabetes Insipidus; Diabetes Mellitus, Experimental; Diuresis; Drug Synergism; Glucagon; Glucose; Glucose Tolerance Test; Humans; Hydrochlorothiazide; Hypoglycemic Agents; Injections, Intravenous; Insulin; Insulin Secretion; Liver; Rabbits; Rats; Sulfonamides; Tolbutamide	1969

Article

Year

DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.

Drug discovery today, 2016, Volume: 21, Issue:4

Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

[Current views on the mode of action of hypoglycemic sulfonamides].

Acta diabetologica latina, 1969, Volume: 6 Suppl 1

Topics: Amino Acids; Animals; Blood Glucose; Chlorpropamide; Diabetes Insipidus; Diabetes Mellitus, Experimental; Diuresis; Drug Synergism; Glucagon; Glucose; Glucose Tolerance Test; Humans; Hydrochlorothiazide; Hypoglycemic Agents; Injections, Intravenous; Insulin; Insulin Secretion; Liver; Rabbits; Rats; Sulfonamides; Tolbutamide

1969

Other Studies

34 other study(ies) available for tolbutamide and hydrochlorothiazide

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach. Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7 Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Interleukin-8; Models, Molecular; Phenylpropionates; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin; Stereoisomerism	2005
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay. Bioorganic & medicinal chemistry letters, 2010, Jan-01, Volume: 20, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Cell Membrane Permeability; Humans; Models, Biological; Quantitative Structure-Activity Relationship; Skin Absorption	2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR. European journal of medicinal chemistry, 2011, Volume: 46, Issue:1 Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics	2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
N-Nitroso derivatives of hydrochlorothiazide, niridazole, and tolbutamide. Toxicology and applied pharmacology, 1977, Volume: 40, Issue:1 Topics: Animals; Chemical Phenomena; Chemistry; Drug Stability; Hydrochlorothiazide; Kinetics; Lethal Dose 50; Male; Methods; Niridazole; Nitroso Compounds; Rats; Solubility; Tolbutamide	1977
Drug-induced hyponatraemia in psychogenic polydipsia. Postgraduate medical journal, 1976, Volume: 52, Issue:613 Topics: Humans; Hydrochlorothiazide; Hyponatremia; Male; Middle Aged; Psychophysiologic Disorders; Schizophrenia; Thirst; Tolbutamide	1976
Hypernatremia due to hypodipsia and elevated threshold for vasopressin release. Effects of treatment with hydrochlorothiazide, chlorpropamide and tolbutamide. The New England journal of medicine, 1968, Nov-28, Volume: 279, Issue:22 Topics: Chlorpropamide; Creatinine; Cyclic AMP; Dehydration; Diuresis; Female; Humans; Hydrochlorothiazide; Hypernatremia; Hypothalamus; Insulin; Insulin Secretion; Islets of Langerhans; Kidney; Middle Aged; Osmolar Concentration; Sodium; Thirst; Tolbutamide; Vasopressins; Water; Water-Electrolyte Balance	1968
The effect of fourteen day treatment with diuretics on mouse blood sugar and glucose tolerance. The Journal of pharmacy and pharmacology, 1972, Volume: 24, Issue:5 Topics: Adrenal Glands; Animals; Blood Glucose; Carbohydrate Metabolism; Ethacrynic Acid; Female; Furosemide; Glucose Tolerance Test; Hydrochlorothiazide; Insulin; Liver Glycogen; Mice; Organ Size; Potassium; Sodium; Time Factors; Tolbutamide	1972
[ADH-like mechanism of action of chlorpropamide in diabetes insipidus (a comparison with the antidiuretic effect of other blood glucose decreasing sulfonamides and hydrochlorothiazide)]. Klinische Wochenschrift, 1970, Jul-15, Volume: 48, Issue:14 Topics: Aged; Blood Glucose; Body Weight; Chlorpropamide; Depression, Chemical; Diabetes Insipidus; Diuresis; Female; Glyburide; Humans; Hydrochlorothiazide; Hypoglycemic Agents; Male; Middle Aged; Natriuresis; Osmolar Concentration; Potassium; Sulfonylurea Compounds; Tolbutamide; Vasopressins	1970
[Antidiuretic action of chlorpropamide in diabetes insipidus]. Iryo, 1971, Volume: 25, Issue:11 Topics: Adolescent; Adult; Aged; Biguanides; Chlorpropamide; Diabetes Insipidus; Female; Humans; Hydrochlorothiazide; Male; Tolbutamide	1971
Generic inequivalence--clinical observations. Acta pharmacologica et toxicologica, 1971, Volume: 29 Suppl 3 Topics: Absorption; Acetaminophen; Administration, Oral; Adult; Aspirin; Biopharmaceutics; Capsules; Chloramphenicol; Delayed-Action Preparations; Drug Compounding; Female; Humans; Hydrochlorothiazide; Phenacetin; Prednisone; Tablets; Tablets, Enteric-Coated; Tetracycline; Therapeutic Equivalency; Time Factors; Tolbutamide; Triamterene	1971
[Chlorpropamide, tolbutamide and saluretics in the treatment of diabetes insipidus sensitive to vasopressin]. Revista clinica espanola, 1970, Feb-15, Volume: 116, Issue:3 Topics: Adult; Child; Chlorpropamide; Diabetes Insipidus; Diuresis; Female; Humans; Hydrochlorothiazide; Male; Tolbutamide; Vasopressins	1970
[Effect of tolbutamide on liver regeneration in partially hepatectomized rats and the toxic influence of hydrochlorothiazide on the liver]. Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete, 1967, Volume: 48, Issue:11 Topics: Animals; Fatty Liver; Hepatectomy; Hydrochlorothiazide; Liver; Liver Regeneration; Organ Size; Potassium; Rats; Tolbutamide	1967
The antidipsic effect of sulphonamides implanted in the hypothalamus of rats. Experientia, 1968, Apr-15, Volume: 24, Issue:4 Topics: Acetazolamide; Animals; Chlorothiazide; Chlorpropamide; Depression, Chemical; Drinking Behavior; Hydrochlorothiazide; Hypothalamo-Hypophyseal System; Hypothalamus; Rats; Sulfadiazine; Sulfonamides; Thirst; Tolbutamide; Vasopressins; Water	1968
Apparatus for determining the rate of drug release from solid dosage forms. Journal of pharmaceutical sciences, 1969, Volume: 58, Issue:5 Topics: Capsules; Hydrochlorothiazide; Methods; Riboflavin; Solubility; Tablets; Time Factors; Tolbutamide	1969
[Modifications of basal blood sugar, glycosuria and the rastinon test induced by treatment with hydrochlorothiazide in aged subjects]. Giornale di gerontologia, 1965, Volume: 13, Issue:5 Topics: Aged; Blood Glucose; Female; Glycosuria; Humans; Hydrochlorothiazide; Male; Tolbutamide	1965
[ON THE PAPER CHROMATOGRAPHIC DISTINCTIONS OF SULFONAMIDE DIURETICS AND SULFONAMIDES WITH OTHER AREAS OF INDICATIONS]. Die Pharmazie, 1963, Volume: 18 Topics: Acetazolamide; Antineoplastic Agents; Carbutamide; Chlorothiazide; Chromatography; Diuretics; Hydrochlorothiazide; Research; Sulfacetamide; Sulfamerazine; Sulfamethoxypyridazine; Sulfanilamide; Sulfanilamides; Sulfathiazoles; Sulfonamides; Tolbutamide	1963
MEBUTAMATE AND HYDROCHLOROTHIAZIDE IN HYPERTENSION. Journal of the American Geriatrics Society, 1964, Volume: 12 Topics: Antihypertensive Agents; Arthritis; Arthritis, Rheumatoid; Blood Pressure Determination; Carbamates; Coronary Disease; Diabetes Mellitus; Digitalis; Geriatrics; Hydrochlorothiazide; Hypertension; Nitroglycerin; Obesity; Parkinsonian Disorders; Prednisolone; Reserpine; Tolbutamide	1964
CONJOINT CLINIC ON DRUGS AND DIABETES. Journal of chronic diseases, 1964, Volume: 17 Topics: Adrenalectomy; Antihypertensive Agents; Benzothiadiazines; Biomedical Research; Blood; Blood Glucose; Body Weight; Chlorothiazide; Chlorpropamide; Diabetes Mellitus; Diazoxide; Diuretics; Dogs; Hydrochlorothiazide; Hypertension; Hypophysectomy; Nitrogen; Pharmacology; Placebos; Polythiazide; Potassium; Rats; Research; Tolbutamide; Toxicology; Trichlormethiazide; Urea	1964
[CLINICAL FINDINGS ON THE BEHAVIOR OF THE TOLBUTAMIDE TEST AFTER TREATMENT WITH HYDROCHLOROTHIAZIDE IN PRESENILE AND SENILE SUBJECTS]. Minerva medica, 1964, Oct-24, Volume: 55 Topics: Biomedical Research; Blood Glucose; Geriatrics; Humans; Hydrochlorothiazide; Pharmacology; Tolbutamide; Toxicology	1964
ETIOLOGICAL FACTORS IN THIAZIDE-INDUCED OR AGGRAVATED DIABETES MELLITUS. Diabetes, 1965, Volume: 14 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Amylases; Blood Chemical Analysis; Blood Urea Nitrogen; Carbohydrate Metabolism; Diabetes Mellitus; Glucose Tolerance Test; Glutathione; Hydrochlorothiazide; Hyperglycemia; Insulin; Pharmacology; Potassium; Thiazides; Tolbutamide; Toxicology; Uric Acid; Urine	1965
MANAGEMENT OF ACNE VULGARIS. Journal of the Indian Medical Association, 1965, Jun-16, Volume: 44 Topics: Acne Vulgaris; Adolescent; Child; Diet; Diet Therapy; Disease Management; Humans; Hydrochlorothiazide; Tolbutamide	1965