Page last updated: 2024-08-16

tolbutamide and hexobarbital

tolbutamide has been researched along with hexobarbital in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199013 (72.22)18.7374
1990's0 (0.00)18.2507
2000's4 (22.22)29.6817
2010's1 (5.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Abraham, MH; Acree, WE; Ibrahim, A1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Breimer, DD; Richter, E; Zilly, W3
Brian, WR; Guengerich, FP; Lloyd, RS; Srivastava, PK; Umbenhauer, DR1
Bacci, MC; Bianchi, C; Bonardi, G; Coppi, G; Molino, C; Tomasi, L; Vidi, A1
Chalabala, M; Lichnerová, I1
Berman, ML; Bochantin, JF1
Balwani, JH; Joglekar, GV1
Biltz, H; Pentz, R; Siegers, CP1
BALWANI, JH; BHIDE, MB; JOGLEKAR, GV; SHROTRI, DS1
BURNS, JJ1
MERKER, HJ; REMMER, H1
MERKER, HJ; REMMER, H; SIEGERT, M1

Reviews

2 review(s) available for tolbutamide and hexobarbital

ArticleYear
[Drugs for rectal application. IV. Absorption of rectally administered drugs].
    Ceskoslovenska farmacie, 1969, Volume: 18, Issue:9

    Topics: Aminohippuric Acids; Aminosalicylic Acids; Aspirin; Emulsions; Hexobarbital; Intestinal Absorption; Lipids; Penicillins; Pharmaceutic Aids; Pharmaceutical Preparations; Phenobarbital; Rectum; Sodium; Solubility; Solvents; Sulfisomidine; Suppositories; Thiopental; Tolbutamide; Water

1969
IMPLICATIONS ON ENZYME INDUCTION FOR DRUG THERAPY.
    The American journal of medicine, 1964, Volume: 37

    Topics: Animals; Benzopyrenes; Cyclizine; Dicumarol; Diphenhydramine; Dogs; Drug Therapy; Enzyme Induction; Enzymes; Glutethimide; Hexobarbital; Liver; Meprobamate; Metabolism; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Probenecid; Rats; Research; Tolbutamide; Toxicology; Zoxazolamine

1964

Other Studies

16 other study(ies) available for tolbutamide and hexobarbital

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Influence of corticosteroid on hexobarbital and tolbutamide disposition.
    Clinical pharmacology and therapeutics, 1978, Volume: 24, Issue:2

    Topics: Adult; Drug Interactions; Glucocorticoids; Half-Life; Hexobarbital; Humans; Kinetics; Male; Prednisone; Time Factors; Tolbutamide

1978
Stimulation of drug metabolism by rifampicin in patients with cirrhosis or cholestasis measured by increased hexobarbital and tolbutamide clearance.
    European journal of clinical pharmacology, 1977, Apr-20, Volume: 11, Issue:4

    Topics: Adult; Aged; Cholestasis; Female; Hexobarbital; Humans; Kinetics; Liver Cirrhosis; Male; Metabolic Clearance Rate; Middle Aged; Rifampin; Stimulation, Chemical; Time Factors; Tolbutamide

1977
Induction of drug metabolism in man after rifampicin treatment measured by increased hexobarbital and tolbutamide clearance.
    European journal of clinical pharmacology, 1975, Dec-19, Volume: 9, Issue:2-3

    Topics: Adult; Creatine; Half-Life; Hexobarbital; Humans; Kinetics; Liver Function Tests; Male; Metabolic Clearance Rate; Models, Biological; Rifampin; Tolbutamide

1975
Expression of a human liver cytochrome P-450 protein with tolbutamide hydroxylase activity in Saccharomyces cerevisiae.
    Biochemistry, 1989, Jun-13, Volume: 28, Issue:12

    Topics: Catalysis; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA; Electrophoresis; Gene Expression Regulation; Genetic Vectors; Hexobarbital; Humans; Liver; Mephenytoin; Mixed Function Oxygenases; Oxidation-Reduction; Plasmids; Saccharomyces cerevisiae; Spectrophotometry, Ultraviolet; Sulfaphenazole; Tolbutamide

1989
Experimental models for the in vivo evaluation of enzyme induction properties of drugs.
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:12

    Topics: Acetanilides; Amides; Aminopyrine; Amphetamine; Aniline Compounds; Animals; Central Nervous System; Codeine; Cyclohexanecarboxylic Acids; Drug Evaluation, Preclinical; Enzyme Activation; Enzyme Induction; Hexobarbital; Male; Meperidine; Mice; Oxotremorine; Pentobarbital; Phenacetin; Phenytoin; Rabbits; Rats; Strychnine; Tolbutamide; Tremorine; Zoxazolamine

1973
Nonspecific stimulation of drug metabolism in rats by methoxyflurane.
    Anesthesiology, 1970, Volume: 32, Issue:6

    Topics: Aminopyrine; Animals; Drug Tolerance; Enzyme Induction; Hexobarbital; Male; Methoxyflurane; Microsomes, Liver; Oxidoreductases; Rats; Sleep; Stimulation, Chemical; Tolbutamide

1970
Effect of chronic administration of tolbutamide on hexobarbitone sleeping time in rats.
    Journal of the Indian medical profession, 1966, Volume: 12, Issue:12

    Topics: Animals; Hexobarbital; Rats; Sleep; Tolbutamide

1966
Effect of diethyldithiocarbamate on the metabolic elimination of hexobarbital, phenazone, tolbutamide and four halogenated hydrocarbons.
    European journal of drug metabolism and pharmacokinetics, 1981, Volume: 6, Issue:2

    Topics: Animals; Antipyrine; Ditiocarb; Hexobarbital; Hydrocarbons, Halogenated; Kinetics; Male; Mice; Mixed Function Oxygenases; Thiocarbamates; Tolbutamide

1981
Potentiation of hexobarbitone anaesthesia by tolbutamide.
    The Indian journal of medical research, 1963, Volume: 51

    Topics: Adjuvants, Anesthesia; Anesthesia; Hexobarbital; Humans; Tolbutamide

1963
EFFECT OF DRUGS ON THE FORMATION OF SMOOTH ENDOPLASMIC RETICULUM AND DRUG-METABOLIZING ENZYMES.
    Annals of the New York Academy of Sciences, 1965, Mar-12, Volume: 123

    Topics: Animals; Electrons; Endoplasmic Reticulum; Endoplasmic Reticulum, Smooth; Esterases; Hexobarbital; Histocytochemistry; Liver; Microscopy; Microscopy, Electron; Oxidoreductases; Pathology; Pharmacology; Phenobarbital; Rats; Research; Spectrophotometry; Tolbutamide; Toxicology

1965
[INCREASE IN DRUG OXIDIZING ENZYME ACTIVITY WITH TOLBUTAMIDE].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1964, Oct-02, Volume: 249

    Topics: Animals; Dogs; Electrons; Hexobarbital; Lagomorpha; Liver; Microscopy; Microscopy, Electron; Rabbits; Research; Tolbutamide; Toxicology

1964