Page last updated: 2024-08-16

tolbutamide and ethinyl estradiol

tolbutamide has been researched along with ethinyl estradiol in 20 studies

Research

Studies (20)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (45.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (15.00)	29.6817
2010's	8 (40.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Gaitonde, BB; Kulkarni, HJ	2
Back, DJ; Stevenson, P; Tjia, JF	1
Back, DJ; Riviere, JH	2
Godsland, IF; Jacobs, HS; Seed, M; Wynn, V	1
Back, DJ; Ma, XN	1
Collu, R; Ducharme, JR; Letarte, J; Polychronakos, C	1
Braga, PC; Cagnetta, G; Copponi, V	1
Cherala, G; Edelman, A; Maslen, C; Pearson, J	1

Trials

1 trial(s) available for tolbutamide and ethinyl estradiol

Article	Year
An ethinyl estradiol-levonorgestrel containing oral contraceptive does not alter cytochrome P4502C9 in vivo activity. Drug metabolism and disposition: the biological fate of chemicals, 2014, Volume: 42, Issue:3 Topics: Adolescent; Adult; Aryl Hydrocarbon Hydroxylases; Contraceptives, Oral, Combined; Cytochrome P-450 CYP2C9; Drug Combinations; Drug Interactions; Ethinyl Estradiol; Female; Humans; Levonorgestrel; Substrate Specificity; Tolbutamide; Young Adult	2014

Article

Year

An ethinyl estradiol-levonorgestrel containing oral contraceptive does not alter cytochrome P4502C9 in vivo activity.

Drug metabolism and disposition: the biological fate of chemicals, 2014, Volume: 42, Issue:3

Topics: Adolescent; Adult; Aryl Hydrocarbon Hydroxylases; Contraceptives, Oral, Combined; Cytochrome P-450 CYP2C9; Drug Combinations; Drug Interactions; Ethinyl Estradiol; Female; Humans; Levonorgestrel; Substrate Specificity; Tolbutamide; Young Adult

2014

Other Studies

19 other study(ies) available for tolbutamide and ethinyl estradiol

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Effect of ethinyl oestradiol and megestrol acetate on carbohydrate metabolism in rabbits. The Indian journal of medical research, 1977, Volume: 66, Issue:2 Topics: Animals; Blood Glucose; Contraceptives, Oral; Contraceptives, Oral, Combined; Depression, Chemical; Ethinyl Estradiol; Fatty Acids, Nonesterified; Female; Insulin; Megestrol; Rabbits; Tolbutamide	1977
Comparative effects of two antimycotic agents, ketoconazole and terbinafine on the metabolism of tolbutamide, ethinyloestradiol, cyclosporin and ethoxycoumarin by human liver microsomes in vitro. British journal of clinical pharmacology, 1989, Volume: 28, Issue:2 Topics: Antifungal Agents; Coumarins; Cyclosporins; Cytochrome P-450 Enzyme System; Ethinyl Estradiol; Female; Humans; In Vitro Techniques; Ketoconazole; Male; Microsomes, Liver; Naphthalenes; Terbinafine; Tolbutamide	1989
Inhibition of ethinyloestradiol and tolbutamide metabolism by quinoline derivatives in vitro. Chemico-biological interactions, 1986, Oct-01, Volume: 59, Issue:3 Topics: Animals; Ethinyl Estradiol; Hydroxylation; Male; Microsomes, Liver; Mixed Function Oxygenases; Quinolines; Rats; Rats, Inbred Strains; Tolbutamide	1986
Effect of mefloquine on hepatic drug metabolism in the rat: comparative study with primaquine. Biochemical pharmacology, 1985, Feb-15, Volume: 34, Issue:4 Topics: Aminopyrine; Animals; Antimalarials; Ethinyl Estradiol; In Vitro Techniques; Male; Mefloquine; Microsomes, Liver; Mixed Function Oxygenases; Primaquine; Quinolines; Rats; Rats, Inbred Strains; Tolbutamide	1985
Oral contraceptive steroids and carbohydrate metabolism. Indian journal of physiology and pharmacology, 1972, Volume: 16, Issue:1 Topics: Animals; Blood Glucose; Carbohydrate Metabolism; Contraceptives, Oral; Diabetes Mellitus; Estrogens; Ethinyl Estradiol; Fatty Acids, Nonesterified; Female; Glucocorticoids; Glucose Tolerance Test; Humans; Insulin; Pregnancy; Rabbits; Tolbutamide	1972
The effects of cyproterone acetate and ethinyl oestradiol on carbohydrate metabolism. Clinical endocrinology, 1984, Volume: 21, Issue:6 Topics: Acne Vulgaris; Adolescent; Adult; Blood Glucose; C-Peptide; Carbohydrate Metabolism; Cyproterone; Cyproterone Acetate; Drug Therapy, Combination; Ethinyl Estradiol; Fasting; Female; Glucose Tolerance Test; Hirsutism; Humans; Insulin; Insulin Resistance; Tolbutamide	1984
Inhibition of hepatic microsomal enzymes by gossypol in the rat. Contraception, 1984, Volume: 30, Issue:1 Topics: Aminopyrine N-Demethylase; Animals; Cytochrome P-450 Enzyme System; Ethinyl Estradiol; Gossypol; Kinetics; Male; Microsomes, Liver; Rats; Rats, Inbred Strains; Tolbutamide	1984
Carbohydrate intolerance in children and adolescents with Turner syndrome. The Journal of pediatrics, 1980, Volume: 96, Issue:6 Topics: Adolescent; Adult; Age Factors; Blood Glucose; Body Weight; Carbohydrate Metabolism; Child; Diabetes Mellitus; Ethinyl Estradiol; Female; Glucose Tolerance Test; Growth Hormone; Humans; Insulin; Mosaicism; Tolbutamide; Turner Syndrome; X Chromosome	1980
[Effects of drugs on the mitochondrial fraction isolated from the liver]. La Clinica terapeutica, 1981, Mar-15, Volume: 96, Issue:5 Topics: Animals; Drug Combinations; Ethinyl Estradiol; Flavonoids; Indomethacin; Isoniazid; Mitochondria, Liver; Norgestrel; Oxygen Consumption; Rabbits; Silymarin; Tolbutamide	1981