Page last updated: 2024-08-16

tolbutamide and c-peptide

tolbutamide has been researched along with c-peptide in 72 studies

Research

Studies (72)

Timeframe	Studies, this research(%)	All Research%
pre-1990	37 (51.39)	18.7374
1990's	28 (38.89)	18.2507
2000's	6 (8.33)	29.6817
2010's	1 (1.39)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Alford, FP; Chisholm, DJ; Larkins, RG; Martin, FI	1
De Nutte, N; De Vroede, M; Gepts, W; Pipeleers, D; Somers, G	1
Dimitriadis, G; Moulopoulos, S; Raptis, S; Zoupas, C	1
Blickle, F; Demangeat, C; Hasselmann, M; Imler, M; Schlienger, JL	1
Beyer, J; Cordes, U; Krause, U	1
Bosquet, F; Cesselin, F; Champigneulle, A; Grimaldi, A; Khalifa, L; Sachon, C; Troupel, S	1
Creutzfeldt, W; Nauck, MA; Siegel, EG	1
Brandhorst, H; Bretzel, RG; Federlin, K; Hering, BJ; Hopt, UT; Hufnagel, B; Klitscher, D; Mellert, J; Pfeffer, F	1
Bergman, RN; Blackwell, J; Dunn, J; Haffner, SM; Mobley, M; Stern, MP	1
Borisova, AM; Kirilov, G; Koev, D	3
Bertrand, J; Demidem, A; Durand, A; Haftek, M; Thivolet, CH	1
van Koetsveld, PM; Verschoor, L; Weber, RF; Weeks, L; Wolffenbuttel, BH	1
Borisova, AM; Kirilov, G; Koev, D; Zlatareva, N	1
Carlo Stella, C; De Caro, L; Ghizzi, A; Gorini, M	1
Kurihara, Y	1
Ikeda, T; Mashiba, H; Mokuda, O; Murakami, I; Tominaga, M	1
Burden, AC; Kinghorn, HA; Samanta, A	1
Borisova, AM; Kirilov, G; Ovcharova, N	1
Joffe, BI; Seftel, HC; Shires, R	1
Baty, J; Dow, RJ; Isles, TE	1
Besch, W; Heinke, P; Ratzmann, KP; Schulz, B	1
Godsland, IF; Jacobs, HS; Seed, M; Wynn, V	1
Burke, MD	1
Fukushima, H; Kitoh, M; Konno, T; Takemiya, M; Uzawa, H; Yamaguchi, K	1
Beuscart, R; Fossati, P; Fourlinnie, JC; Romon, M; Vaast, D; Vie, MC; Wemeau, JL	1
Beuscart, R; Coequyt, S; Vergnes, R; Vie, MC; Wemeau, JL	1
Beischer, W; Heinze, E; Teller, W; Thon, A; Vetter, U	1
Kobayashi, T; Nihei, J; Ohneda, A; Sakai, T	1
Frankel, BJ; Freedman, ZR; Fujiya, H; Grodsky, GM; Karam, JH; Lewitt, PA; Nowlain, RE; Young, CW	1
Brennan, MD; Carpenter, AM; Edis, AJ; Rubenstein, AH; Service, FJ	1
Ginsberg-Fellner, F; Horwitz, DL; Mirel, RD; Rayfield, EJ	1
Kumahara, Y; Matsuyama, T; Sawazaki, N; Shima, K; Tanaka, R; Yanaihara, N	1
Dellenbach, P; Goettenberg, N; Schlienger, JL	1
Kallio, H; Karonen, SL; Pelkonen, R; Suoranta, H	1
Moulin, JP; Vague, P	1
Cowett, RM; Rubenstein, AH; Schwartz, R; Susa, JB; Widness, JA; Zeller, WP	1
Groop, L; Tötterman, KJ	1
Damsgaard, EM; Faber, O; Frøland, A; Iversen, S	1
Bohannon, NV; Grodsky, GM; Karam, JH; Lorenzi, M	1
Dreyer, M; Kühnau, J; Rüdiger, HW	1
Horswill, CA; Kien, CL; McCoy, KS; O'Dorisio, T; Zipf, WB	1
Appel, S; Hitzenberger, G; Kalafsky, G; Kallay, Z; Kutz, K; Rüfenacht, T; Tetzloff, W	1
Hinds, A; Parsons, HG; Sheehan, AG	1
Christensen, NJ; Christiansen, E; Madsbad, S; Pedersen, O; Rasmussen, K; Tibell, A; Tydén, G; Võlund, A	1
Boyle, PJ; Justice, KM; Krentz, AJ; Schade, DS; Wright, AD	1
Christiansen, E; Madsbad, S; Rasmussen, K; Tibell, A; Tydén, G	1
Bergman, RN; Harry, DS; Kruszynska, YT; McIntyre, N	1
Giacca, A; Groenewoud, Y; Lewis, GF; Vranic, M; Zinman, B	1
Hara, T; Hotta, N; Koh, N; Nakamura, J; Sakakibara, F; Takeuchi, N	1
Bedford, C; George, E; Hardisty, CA; Harris, N; Heller, SR; Macdonald, IA; Peacey, SR; Rostami-Hodjegan, A; Tucker, GT	1
Cottrell, DA	1
Ader, M; Bergman, RN; Rebrin, K; Steil, G; Watanabe, R	1
Bijlstra, PJ; Lutterman, JA; Russel, FG; Smits, P; Thien, T	1
Clausen, JO; Echwald, SM; Hansen, L; Hansen, T; Pedersen, O; Urhammer, SA	1
Giacca, A; Lewis, GF; Vranic, M	1
George, E; Heller, SR; Peacey, SR; Rostami-Hodjegan, A; Tucker, GT	2
Giacca, A; Harley, P; Lewis, GF; Vranic, M	1
Awata, T; Inoue, I; Katayama, S; Negishi, K; Noji, S; Takahashi, K	1
Chen, YD; Maheux, P; Polonsky, KS; Reaven, GM	1
Cherrington, AD; Edgerton, D; Sindelar, DK	1
Carpentier, A; Giacca, A; Lewis, GF; Vranic, M	1
Bilinski, D; Carpentier, A; Giacca, A; Lewis, GF; Vranic, M	1
Ambye, L; Echwald, SM; Ferrer, J; Grarup, N; Hansen, L; Hansen, T; Pedersen, O	1
Kjems, LL; Madsbad, S; Vølund, A	1
Huopio, H; Komulainen, J; Laakso, M; Niskanen, L; Otonkoski, T; Vauhkonen, I	1
AvRuskin, TW; Juan, CS	1
Huopio, H; Jääskeläinen, J; Kärkkäinen, P; Komulainen, J; Laakso, M; Miettinen, R; Otonkoski, T; Tapanainen, P; Voutilainen, R	1
Assenova, B; Borissova, AM; Kirilov, G; Krivoshiev, S; Tchetirska, M; Vazelov, E	1
Abdel-Wahab, YH; Flatt, PR; McKillop, AM; Ng, MT	1

Reviews

3 review(s) available for tolbutamide and c-peptide

Article	Year
[ROC analysis: an aid in medical decisions]. LARC medical, 1983, Volume: 3, Issue:4 Topics: Blood Glucose; C-Peptide; Clinical Competence; Clinical Laboratory Techniques; Diabetes Mellitus; Humans; Statistics as Topic; Tolbutamide	1983
Toward an integrated phenotype in pre-NIDDM. Diabetic medicine : a journal of the British Diabetic Association, 1996, Volume: 13, Issue:9 Suppl 6 Topics: Animals; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Glucose; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Liver; Models, Biological; Phenotype; Prediabetic State; Risk Factors; Tolbutamide	1996
The direct and indirect effects of insulin on hepatic glucose production in vivo. Diabetologia, 1998, Volume: 41, Issue:9 Topics: Animals; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Glucose; Humans; Hypoglycemic Agents; Insulin; Liver; Reference Values; Tolbutamide	1998

Trials

10 trial(s) available for tolbutamide and c-peptide

Article	Year
A randomized crossover study of sulphonylurea and insulin treatment in patients with type 2 diabetes poorly controlled on dietary therapy. Diabetic medicine : a journal of the British Diabetic Association, 1989, Volume: 6, Issue:6 Topics: Blood Glucose; C-Peptide; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Diet, Diabetic; Fasting; Female; Glyburide; Glycated Hemoglobin; Humans; Insulin; Islets of Langerhans; Male; Middle Aged; Random Allocation; Tolbutamide	1989
A comparative study of sulphonylurea and insulin therapy in non insulin dependent diabetics who had failed on diet therapy alone. Diabetes research (Edinburgh, Scotland), 1987, Volume: 4, Issue:4 Topics: Adult; Aged; Blood Glucose; Body Weight; C-Peptide; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Diet, Diabetic; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Insulin; Middle Aged; Tolbutamide	1987
The effect of nicardipine on glucose and drug-stimulated insulin secretion in normal volunteers. British journal of clinical pharmacology, 1985, Volume: 20 Suppl 1 Topics: Adult; Blood Glucose; C-Peptide; Calcium Channel Blockers; Glucose; Humans; Insulin; Insulin Secretion; Male; Nicardipine; Nifedipine; Tolbutamide	1985
Propranolol does not inhibit sulphonylurea-stimulated insulin secretion in patients with non-insulin dependent diabetes mellitus. Acta endocrinologica, 1982, Volume: 100, Issue:3 Topics: Aged; Blood Glucose; C-Peptide; Clinical Trials as Topic; Diabetes Mellitus; Double-Blind Method; Female; Glipizide; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Male; Middle Aged; Propranolol; Random Allocation; Sulfonylurea Compounds; Tolbutamide	1982
Therapeutic effect of tolbutamide in non-insulin dependent diabetes mellitus (NIDDM). Relation to beta-cell function. Acta endocrinologica, 1982, Volume: 100, Issue:3 Topics: Adult; Aged; Blood Glucose; C-Peptide; Clinical Trials as Topic; Diabetes Mellitus; Double-Blind Method; Female; Glycated Hemoglobin; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Middle Aged; Random Allocation; Tolbutamide	1982
Lack of interaction between fluvastatin and oral hypoglycemic agents in healthy subjects and in patients with non-insulin-dependent diabetes mellitus. The American journal of cardiology, 1995, Jul-13, Volume: 76, Issue:2 Topics: Administration, Oral; Anticholesteremic Agents; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Diclofenac; Drug Interactions; Fatty Acids, Monounsaturated; Fluvastatin; Glyburide; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Insulin; Lovastatin; Placebos; Simvastatin; Tolbutamide	1995
Insulin secretion, insulin action and non-insulin-dependent glucose uptake in pancreas transplant recipients. The Journal of clinical endocrinology and metabolism, 1994, Volume: 79, Issue:6 Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Kidney Transplantation; Kinetics; Male; Middle Aged; Pancreas Transplantation; Tolbutamide	1994
An importance of carbohydrate ingestion for the expression of the effect of alpha-glucosidase inhibitor in NIDDM. Diabetes care, 1996, Volume: 19, Issue:6 Topics: Biomarkers; Blood Glucose; C-Peptide; Circadian Rhythm; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Energy Intake; Enzyme Inhibitors; Follow-Up Studies; Glyburide; Glycated Hemoglobin; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Inpatients; Insulin; Middle Aged; Regression Analysis; Retrospective Studies; Sulfonylurea Compounds; Tolbutamide	1996
Acarbose controls postprandial hyperproinsulinemia in non-insulin dependent diabetes mellitus. Diabetes research and clinical practice, 1997, Volume: 36, Issue:3 Topics: Acarbose; Aged; Blood Glucose; C-Peptide; Cholesterol; Cholesterol, HDL; Diabetes Mellitus, Type 2; Fasting; Gliclazide; Glucose Intolerance; Glycated Hemoglobin; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin; Middle Aged; Postprandial Period; Proinsulin; Time Factors; Tolbutamide; Triglycerides; Trisaccharides	1997
L-carnitine consecutively administered to patients on hemodialysis improves beta-cell response. The International journal of artificial organs, 2003, Volume: 26, Issue:4 Topics: Adult; Blood Glucose; C-Peptide; Carbohydrate Metabolism; Carnitine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Islets of Langerhans; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Time Factors; Tolbutamide	2003

Other Studies

59 other study(ies) available for tolbutamide and c-peptide

Article	Year
Relationship between alpha and beta cell function before and after metabolic control in ketotic diabetic subjects. The Journal of clinical endocrinology and metabolism, 1978, Volume: 46, Issue:1 Topics: Adolescent; Adult; C-Peptide; Diabetic Ketoacidosis; Female; Glucagon; Glucose; Growth Hormone; Humans; Insulin; Islets of Langerhans; Male; Middle Aged; Tolbutamide	1978
Plasma pancreatic hormone levels in a case of somatostatinoma: diagnostic and therapeutic implications. The Journal of clinical endocrinology and metabolism, 1979, Volume: 49, Issue:4 Topics: C-Peptide; Diabetes Complications; Female; Glucagon; Humans; Middle Aged; Pancreatic Neoplasms; Pancreatic Polypeptide; Radioimmunoassay; Somatostatin; Streptozocin; Tolbutamide	1979
The use of artificial beta cell in diagnosis and treatment of insulinoma. Hormone and metabolic research. Supplement series, 1979, Issue:8 Topics: Adenoma, Islet Cell; Adult; Artificial Organs; Blood Glucose; C-Peptide; Feedback; Female; Humans; Insulin; Islets of Langerhans; Male; Middle Aged; Monitoring, Physiologic; Pancreatic Neoplasms; Tolbutamide	1979
[Insulin secretion in alcoholic hepatopathy: analysis by measurement of C-peptide (author's transl)]. La Nouvelle presse medicale, 1978, Dec-09, Volume: 7, Issue:44 Topics: Adolescent; Adult; C-Peptide; Fatty Liver, Alcoholic; Female; Glucose Tolerance Test; Humans; Hyperinsulinism; Insulin; Insulin Secretion; Liver Cirrhosis, Alcoholic; Male; Middle Aged; Peptides; Tolbutamide	1978
[C-peptide: secretion and metabolism in different functional states and with abnormal B-cell function (author's transl)]. Deutsche medizinische Wochenschrift (1946), 1977, May-27, Volume: 102, Issue:21 Topics: C-Peptide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucose; Half-Life; Humans; Insulin; Pancreatectomy; Peptides; Tolbutamide	1977
Does glucagon preserve its insulinogenic effect during tolbutamide-induced hypoglycemia? Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1992, Volume: 24, Issue:11 Topics: Adult; C-Peptide; Glucagon; Humans; Hypoglycemia; Insulin; Tolbutamide	1992
Prolonged maximal stimulation of insulin secretion in healthy subjects does not provoke preferential release of proinsulin. Pancreas, 1991, Volume: 6, Issue:6 Topics: Adult; C-Peptide; Diabetes Mellitus, Type 2; Female; Glucagon; Humans; Hyperglycemia; Insulin; Insulin Secretion; Insulinoma; Male; Pancreatic Neoplasms; Proinsulin; Tolbutamide	1991
Exchange of pancreata and islets between centers for experimental islet transplantation in the pig. Transplantation proceedings, 1991, Volume: 23, Issue:5 Topics: Animals; Blood Glucose; C-Peptide; Insulin; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Pancreas; Pancreatectomy; Swine; Tolbutamide; Transplantation, Autologous	1991
Diminished insulin sensitivity and increased insulin response in nonobese, nondiabetic Mexican Americans. Metabolism: clinical and experimental, 1990, Volume: 39, Issue:8 Topics: Analysis of Variance; Anthropometry; Blood Glucose; C-Peptide; Fasting; Female; Glucose Tolerance Test; Hispanic or Latino; Humans; Insulin; Insulin Secretion; Male; Mexico; Tolbutamide; United States	1990
[High-degree obesity--a risk factor for the development of diabetes mellitus]. Vutreshni bolesti, 1990, Volume: 29, Issue:3 Topics: Adolescent; Adult; C-Peptide; Diabetes Mellitus; Female; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin Secretion; Male; Middle Aged; Obesity; Risk Factors; Tolbutamide	1990
Structure, function, and immunogenicity of human insulinoma cells. Diabetes, 1988, Volume: 37, Issue:9 Topics: 1-Methyl-3-isobutylxanthine; Adenoma, Islet Cell; Adult; C-Peptide; Fluorescent Antibody Technique; Glucagon; Glucose; Humans; Insulin; Insulin Secretion; Insulinoma; Lymphocyte Culture Test, Mixed; Lymphocytes; Microscopy, Electron; Pancreatic Neoplasms; Tolbutamide; Tumor Cells, Cultured	1988
[An improvement in insulin efficacy in patients with type-1 diabetes mellitus following treatment using an insulin infusion pump]. Vutreshni bolesti, 1989, Volume: 28, Issue:1 Topics: Blood Glucose; C-Peptide; Chronic Disease; Diabetes Mellitus, Type 1; Drug Evaluation; Humans; Insulin; Insulin Infusion Systems; Tolbutamide	1989
[Effect of antihypertensive drugs on insulin secretion and efficacy]. Vutreshni bolesti, 1989, Volume: 28, Issue:2 Topics: Adult; Aged; Antihypertensive Agents; C-Peptide; Diabetes Mellitus, Type 2; Drug Evaluation; Drug Interactions; Female; Humans; Hypertension; Insulin; Insulin Infusion Systems; Insulin Secretion; Male; Middle Aged; Tolbutamide	1989
[Factors affecting stability in the course of insulin-dependent diabetes mellitus]. Vutreshni bolesti, 1989, Volume: 28, Issue:3 Topics: Adolescent; Adult; Blood Glucose; C-Peptide; Chronic Disease; Circadian Rhythm; Diabetes Mellitus, Type 1; Female; Humans; Insulin Infusion Systems; Insulin Resistance; Islets of Langerhans; Male; Middle Aged; Tolbutamide	1989
[Biochemical diagnosis of insulinoma: correlations between blood glucose, blood insulin and the titer of plasma non-esterified fatty acids during fasting and during various diagnostic tests]. Minerva medica, 1985, Sep-29, Volume: 76, Issue:37 Topics: Adenoma, Islet Cell; Adult; Aged; Blood Glucose; C-Peptide; Epinephrine; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulinoma; Male; Middle Aged; Tolbutamide	1985
[Studies on the diagnosis of insulinoma]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1987, Volume: 62, Issue:1 Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Blood Glucose; C-Peptide; Female; Glucagon; Humans; Insulin; Insulin Secretion; Insulinoma; Male; Middle Aged; Pancreatic Neoplasms; Tolbutamide	1987
Plasma glucose response after intravenous injection of tolbutamide in insulin-treated type I and type II diabetic patients. Experimental and clinical endocrinology, 1988, Volume: 91, Issue:3 Topics: Adult; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Humans; Injections, Intravenous; Insulin; Male; Middle Aged; Tolbutamide	1988
[Insulin secretion and action in acromegaly]. Vutreshni bolesti, 1987, Volume: 26, Issue:6 Topics: Acromegaly; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucose Tolerance Test; Growth Hormone; Humans; Insulin; Insulin Secretion; Male; Prolactin; Time Factors; Tolbutamide	1987
Maximal pancreatic beta-cell stimulation and the counter-regulatory hormonal responses in South African black and white obese subjects. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1985, May-25, Volume: 67, Issue:21 Topics: Adult; Black or African American; Blood Glucose; C-Peptide; Female; Glucagon; Glucose; Humans; Insulin; Islets of Langerhans; Obesity; Time Factors; Tolbutamide; White People	1985
Tolbutamide does not alter insulin requirement in Type 1 (insulin-dependent) diabetes. Diabetologia, 1984, Volume: 27, Issue:1 Topics: Adult; C-Peptide; Diabetes Mellitus, Type 1; Drug Synergism; Fatty Acids, Nonesterified; Glucagon; Glycerol; Humans; Insulin Infusion Systems; Male; Middle Aged; Somatostatin; Tolbutamide	1984
The effects of cyproterone acetate and ethinyl oestradiol on carbohydrate metabolism. Clinical endocrinology, 1984, Volume: 21, Issue:6 Topics: Acne Vulgaris; Adolescent; Adult; Blood Glucose; C-Peptide; Carbohydrate Metabolism; Cyproterone; Cyproterone Acetate; Drug Therapy, Combination; Ethinyl Estradiol; Fasting; Female; Glucose Tolerance Test; Hirsutism; Humans; Insulin; Insulin Resistance; Tolbutamide	1984
Hypoglycemia: test strategies for laboratory evaluation. Comprehensive therapy, 1980, Volume: 6, Issue:5 Topics: Adenoma, Islet Cell; Blood Glucose; C-Peptide; Food; Food Deprivation; Glucose Tolerance Test; Humans; Hypoglycemia; Infant, Newborn; Infant, Newborn, Diseases; Insulin; Radioimmunoassay; Tolbutamide	1980
A case with glucagonoma syndrome--endocrine and metabolic studies. Endocrinologia japonica, 1981, Volume: 28, Issue:2 Topics: Adenoma, Islet Cell; C-Peptide; Endocrine Glands; Female; Glucagon; Glucagonoma; Glucose Tolerance Test; Humans; Insulin; Liver Neoplasms; Middle Aged; Pancreatic Neoplasms; Tolbutamide	1981
[Basal C peptide levels in response to intravenous tolbutamide in the detection of incorrect insulin therapy (or prolonged misuse)]. La Revue de medecine interne, 1983, Volume: 4, Issue:1 Topics: Adolescent; Adult; Aged; C-Peptide; Diabetes Mellitus; Female; Humans; Injections, Intravenous; Insulin; Male; Middle Aged; Peptides; Tolbutamide	1983
The effect of glucose, tolbutamide, and arginine on C-peptide release during remission in type I diabetes mellitus. European journal of pediatrics, 1983, Volume: 140, Issue:4 Topics: Adolescent; Arginine; C-Peptide; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Glucose; Humans; Insulin; Male; Tolbutamide	1983
Analysis of insulin secretion based on changes in plasma insulin and C-peptide in man. The Tohoku journal of experimental medicine, 1982, Volume: 138, Issue:4 Topics: Adult; Aged; Arginine; C-Peptide; Diabetes Mellitus; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Liver Cirrhosis; Male; Middle Aged; Nephritis; Pancreatic Neoplasms; Peptides; Tolbutamide	1982
Insulinopenic diabetes after rodenticide (Vacor) ingestion: a unique model of acquired diabetes in man. Diabetes, 1980, Volume: 29, Issue:12 Topics: Adult; Arginine; Blood Glucose; C-Peptide; Child; Diabetes Mellitus; Diabetic Ketoacidosis; Diabetic Neuropathies; Glucagon; Glucose Tolerance Test; Humans; Insulin; Islets of Langerhans; Male; Phenylurea Compounds; Tolbutamide	1980
Diagnosis of pancreatic islet hyperplasia causing hypoglycemia in a patient with portacaval anastomosis. The American journal of medicine, 1980, Volume: 68, Issue:6 Topics: Blood Chemical Analysis; Blood Glucose; C-Peptide; Female; Glucagon; Glucose Tolerance Test; Humans; Hyperplasia; Hypoglycemia; Insulin; Islets of Langerhans; Middle Aged; Portacaval Shunt, Surgical; Tolbutamide	1980
C-Peptide reserve in insulin-dependent diabetes. Comparative responses to glucose, glucagon and tolbutamide. Diabetologia, 1980, Volume: 19, Issue:3 Topics: Adolescent; Adult; Blood Glucose; C-Peptide; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Islets of Langerhans; Kinetics; Male; Peptides; Tolbutamide	1980
Failure of exogenous insulin to inhibit C-peptide release from the perfused rat pancreas. Endocrinologia japonica, 1980, Volume: 27, Issue:3 Topics: Animals; Arginine; C-Peptide; Glucagon; Glucose; Insulin; Male; Pancreas; Peptides; Perfusion; Rats; Tolbutamide	1980
[Glucose tolerance on long-term treatment with a progestogen (etynodiol diacetate) (author's transl)]. Journal de gynecologie, obstetrique et biologie de la reproduction, 1980, Volume: 9, Issue:4 Topics: Adult; C-Peptide; Ethynodiol Diacetate; Female; Glucose; Glucose Tolerance Test; Humans; Insulin; Time Factors; Tolbutamide; Uterine Diseases	1980
Plasma insulin, C-peptide, and blood glucose in portal, hepatic and peripheral veins in liver cirrhosis. Effect of intravenous tolbutamide. Acta endocrinologica, 1981, Volume: 97, Issue:4 Topics: Adult; Blood; Blood Glucose; C-Peptide; Female; Hepatic Veins; Humans; Insulin; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Liver Cirrhosis, Biliary; Male; Middle Aged; Peptides; Portal Vein; Tolbutamide; Veins	1981
The defective glucose sensitivity of the B cell in non insulin dependent diabetes. Improvement after twenty hours of normoglycaemia. Metabolism: clinical and experimental, 1982, Volume: 31, Issue:2 Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus; Fasting; Female; Glucose; Humans; Insulin; Islets of Langerhans; Male; Middle Aged; Time Factors; Tolbutamide	1982
Permanent neonatal diabetes in an infant of an insulin-dependent mother. The Journal of pediatrics, 1982, Volume: 100, Issue:6 Topics: C-Peptide; Diabetes Mellitus, Type 1; Humans; Infant, Newborn; Insulin; Male; Receptor, Insulin; Tolbutamide	1982
Stimulatory effects of tolbutamide infusion on plasma glucagon in insulin-dependent diabetic subjects. The Journal of clinical endocrinology and metabolism, 1982, Volume: 54, Issue:2 Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus; Female; Glucagon; Humans; Kinetics; Male; Middle Aged; Tolbutamide	1982
Chlorpropamide-alcohol flushing is not useful for individual genetic counseling of diabetic patients. Clinical genetics, 1980, Volume: 18, Issue:3 Topics: Adolescent; Adult; Blushing; C-Peptide; Child; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Ethanol; Genetic Counseling; Humans; Middle Aged; Risk; Tolbutamide	1980
Elevated hepatic glucose production in children with cystic fibrosis. Pediatric research, 1995, Volume: 37, Issue:5 Topics: C-Peptide; Child; Cystic Fibrosis; Fasting; Female; Glucose; Humans; Infusions, Intravenous; Insulin; Liver; Male; Tolbutamide	1995
Tolbutamide causes a modest increase in insulin secretion in cystic fibrosis patients with impaired glucose tolerance. Metabolism: clinical and experimental, 1995, Volume: 44, Issue:1 Topics: Administration, Oral; Adolescent; Adult; C-Peptide; Cystic Fibrosis; Female; Glucagon; Glucose; Glucose Tolerance Test; Humans; Infusions, Intravenous; Insulin; Insulin Secretion; Male; Tolbutamide	1995
Successful treatment of severe refractory sulfonylurea-induced hypoglycemia with octreotide. Diabetes care, 1993, Volume: 16, Issue:1 Topics: Adult; Blood Glucose; C-Peptide; Coma; Humans; Hypoglycemia; Male; Octreotide; Tolbutamide	1993
Defects in quantitative and qualitative beta-cell function following successful segmental pancreas transplantation. Danish-Swedish Study Group of Metabolic Effect of Pancreas Transplantation (DSSGMEPT). Transplantation proceedings, 1993, Volume: 25, Issue:1 Pt 2 Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Eating; Fasting; Glucagon; Glycated Hemoglobin; Humans; Islets of Langerhans; Kidney Transplantation; Middle Aged; Pancreas Transplantation; Reference Values; Tolbutamide	1993
Insulin sensitivity, insulin secretion and glucose effectiveness in diabetic and non-diabetic cirrhotic patients. Diabetologia, 1993, Volume: 36, Issue:2 Topics: Administration, Oral; Adult; Blood Glucose; C-Peptide; Diabetes Mellitus; Glucose; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Injections, Intravenous; Insulin; Insulin Resistance; Liver Cirrhosis; Middle Aged; Tolbutamide	1993
Hepatic glucose production is regulated both by direct hepatic and extrahepatic effects of insulin in humans. Diabetes, 1996, Volume: 45, Issue:4 Topics: Adult; Algorithms; Analysis of Variance; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Gluconeogenesis; Glucose Clamp Technique; Homeostasis; Humans; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Insulin Secretion; Kinetics; Liver; Male; Portal System; Reference Values; Tolbutamide	1996
Similar physiological and symptomatic responses to sulphonylurea and insulin induced hypoglycaemia in normal subjects. Diabetic medicine : a journal of the British Diabetic Association, 1996, Volume: 13, Issue:7 Topics: Adult; Blood Glucose; C-Peptide; Cognition; Dose-Response Relationship, Drug; Epinephrine; Female; Glucagon; Glucose Clamp Technique; Hemodynamics; Humans; Hypoglycemia; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Insulin, Regular, Pork; Male; Reaction Time; Recombinant Proteins; Sweating; Tolbutamide; Tremor	1996
Normalization of insulin sensitivity and glucose homeostasis in type I diabetic pancreas transplant recipients: a 48-month cross-sectional study--a clinical research center study. The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:10 Topics: Adult; Blood Glucose; C-Peptide; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Female; Food; Glucose Tolerance Test; Homeostasis; Humans; Hypoglycemic Agents; Insulin; Kidney Transplantation; Kinetics; Male; Pancreas Transplantation; Tolbutamide	1996
Effects of tolbutamide on vascular ATP-sensitive potassium channels in humans. Comparison with literature data on glibenclamide and glimepiride. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1996, Volume: 28, Issue:9 Topics: Adenosine Triphosphate; Adult; Blood Glucose; C-Peptide; Forearm; Humans; Hypoglycemic Agents; Insulin; Male; Potassium Channels; Tolbutamide; Vasodilation	1996
Amino acid polymorphisms in the ATP-regulatable inward rectifier Kir6.2 and their relationships to glucose- and tolbutamide-induced insulin secretion, the insulin sensitivity index, and NIDDM. Diabetes, 1997, Volume: 46, Issue:3 Topics: Adenosine Triphosphate; Adult; Blood Glucose; C-Peptide; Cohort Studies; Denmark; Diabetes Mellitus, Type 2; DNA Primers; Female; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Male; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Single-Stranded Conformational; Potassium Channels; Potassium Channels, Inwardly Rectifying; Reference Values; Tolbutamide; White People	1997
Glucagon enhances the direct suppressive effect of insulin on hepatic glucose production in humans. The American journal of physiology, 1997, Volume: 272, Issue:3 Pt 1 Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Drug Synergism; Glucagon; Glucose; Humans; Insulin; Liver; Liver Circulation; Male; Tolbutamide	1997
The use of tolbutamide-induced hypoglycemia to examine the intraislet role of insulin in mediating glucagon release in normal humans. The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:5 Topics: Adult; Blood Glucose; C-Peptide; Epinephrine; Female; Glucagon; Glucose Clamp Technique; Humans; Hypoglycemia; Insulin; Islets of Langerhans; Kinetics; Male; Tolbutamide	1997
Fatty acids mediate the acute extrahepatic effects of insulin on hepatic glucose production in humans. Diabetes, 1997, Volume: 46, Issue:7 Topics: Adult; C-Peptide; Cohort Studies; Fat Emulsions, Intravenous; Fatty Acids, Nonesterified; Glucagon; Glucose; Glucose Clamp Technique; Heparin; Humans; Hyperinsulinism; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Liver; Male; Time Factors; Tolbutamide; Triglycerides; Tritium	1997
Evidence that insulin can directly inhibit hepatic glucose production. Diabetologia, 1997, Volume: 40, Issue:11 Topics: Adult; Blood Glucose; C-Peptide; Female; Glucose; Humans; Hypoglycemic Agents; Insulin; Liver; Male; Metabolic Clearance Rate; Middle Aged; Tolbutamide	1997
Population-based modeling to demonstrate extrapancreatic effects of tolbutamide. The American journal of physiology, 1998, Volume: 274, Issue:4 Topics: C-Peptide; Glucose Clamp Technique; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Kinetics; Models, Biological; Population Surveillance; Tolbutamide	1998
Resistance to insulin's acute direct hepatic effect in suppressing steady-state glucose production in individuals with type 2 diabetes. Diabetes, 1999, Volume: 48, Issue:3 Topics: Adult; Animals; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Dogs; Fatty Acids, Nonesterified; Female; Glucagon; Gluconeogenesis; Glucose Clamp Technique; Humans; Infusions, Intravenous; Insulin; Insulin Secretion; Liver; Male; Middle Aged; Portal System; Tolbutamide	1999
Counterregulatory response to hypoglycemia differs according to the insulin delivery route, but does not affect glucose production in normal humans. The Journal of clinical endocrinology and metabolism, 1999, Volume: 84, Issue:3 Topics: Adult; Blood Glucose; C-Peptide; Fatty Acids, Nonesterified; Glucose; Hormones; Humans; Hyperinsulinism; Hypoglycemia; Hypoglycemic Agents; Injections, Intravenous; Insulin; Lactic Acid; Male; Portal Vein; Reference Values; Tolbutamide; Veins	1999
Genetic variability of the SUR1 promoter in relation to beta-cell function and Type II diabetes mellitus. Diabetologia, 2001, Volume: 44, Issue:10 Topics: Adult; Aged; Alleles; ATP-Binding Cassette Transporters; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; DNA Mutational Analysis; Female; Gene Frequency; Genetic Variation; Glucose Tolerance Test; Humans; Insulin; Islets of Langerhans; Kinetics; Male; Middle Aged; Polymorphism, Genetic; Polymorphism, Single-Stranded Conformational; Potassium Channels; Potassium Channels, Inwardly Rectifying; Promoter Regions, Genetic; Receptors, Drug; Sulfonylurea Receptors; Tolbutamide	2001
Quantification of beta-cell function during IVGTT in Type II and non-diabetic subjects: assessment of insulin secretion by mathematical methods. Diabetologia, 2001, Volume: 44, Issue:10 Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Mathematics; Middle Aged; Models, Biological; Tolbutamide	2001
Carriers of an inactivating beta-cell ATP-sensitive K(+) channel mutation have normal glucose tolerance and insulin sensitivity and appropriate insulin secretion. Diabetes care, 2002, Volume: 25, Issue:1 Topics: Adult; Amino Acid Substitution; ATP-Binding Cassette Transporters; C-Peptide; Female; Genetic Carrier Screening; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mutation, Missense; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Sulfonylurea Receptors; Tolbutamide	2002
Transient neonatal diabetes mellitus, type 4, type 1 diabetes mellitus, or MODY: which disease is it, anyway? Journal of pediatric endocrinology & metabolism : JPEM, 2002, Volume: 15, Issue:5 Topics: Adult; Arginine; C-Peptide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Glucose Tolerance Test; Humans; Infant; Insulin; Insulin Secretion; Islets of Langerhans; Male; Tolbutamide	2002
Acute insulin response tests for the differential diagnosis of congenital hyperinsulinism. The Journal of clinical endocrinology and metabolism, 2002, Volume: 87, Issue:10 Topics: Adolescent; Adult; C-Peptide; Calcium; Child; Child, Preschool; Diagnosis, Differential; DNA Mutational Analysis; Female; Glucose Tolerance Test; Glycosyltransferases; Humans; Hyperinsulinism; Insulin; Islets of Langerhans; Male; Membrane Proteins; Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Potassium Channels, Inwardly Rectifying; Repressor Proteins; Saccharomyces cerevisiae Proteins; Sequence Analysis, DNA; Tolbutamide	2002
Evidence for inhibitory autocrine effects of proinsulin C-peptide on pancreatic β-cell function and insulin secretion. Diabetes, obesity & metabolism, 2014, Volume: 16, Issue:10 Topics: Animals; C-Peptide; Cell Line; Diazoxide; Glucagon-Like Peptide 1; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Mice; Rats; Tolbutamide	2014