tolbutamide has been researched along with atropine in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (39.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (21.43) | 29.6817 |
| 2010's | 11 (39.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Reidenberg, MM | 1 |
| Blackard, WG; Kikuchi, M; Rabinovitch, A; Renold, AE | 1 |
| Rasmussen, H; Zawalich, KC; Zawalich, WS | 1 |
| Loubatières, A; Loubatières-Mariani, MM | 1 |
| Mandelbaum, I; Morgan, CR | 1 |
| Hales, CN; Milner, RD | 1 |
| Burnett, MA; Lang, DA; Matthews, DR; Turner, RC | 1 |
| Correas, I; Felíu, JE; Marco, J; Villanueva, ML; Vincent, E; Zulueta, MA | 1 |
| Lux, G; Rösch, W | 1 |
| Ho, JW; Leung, YK | 1 |
| ARIMASA, S; FUJII, H; KOBAYASHI, J; OTA, T; SAKAKIBARA, N; SHIMIZU, J; YOSHIDA, H | 2 |
1 review(s) available for tolbutamide and atropine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
27 other study(ies) available for tolbutamide and atropine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Obesity and fasting--effects on drug metabolism and drug action in man.
Topics: Adult; Animals; Antipyrine; Atropine; Blood Proteins; Fasting; Female; Humans; Isoniazid; Obesity; Pharmaceutical Preparations; Procaine; Protein Binding; Sulfisoxazole; Tolbutamide | 1977 |
An effect of hyposmolarity on insulin release in vitro.
Topics: Amiloride; Amylases; Animals; Atropine; Calcium; Choline; Colchicine; Diazoxide; Epinephrine; Glucagon; Glucose; Hypotonic Solutions; Imidazoles; In Vitro Techniques; Insulin; Insulin Secretion; Male; Osmolar Concentration; Ouabain; Pancreas; Phentolamine; Phenytoin; Propranolol; Rats; Sorbitol; Tolbutamide; Trypsin Inhibitors; Vinblastine | 1975 |
Cholinergic agonists prime the beta-cell to glucose stimulation.
Topics: Animals; Arginine; Atropine; Carbachol; Drug Synergism; Glucose; In Vitro Techniques; Inositol; Inositol Phosphates; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Rats; Rats, Inbred Strains; Tolbutamide | 1989 |
In vitro secretion of insulin after glucose, sulphonylureas, adrenergic and cholinergic substances studied by isolated perfused rat pancreas.
Topics: Acetylcholine; Animals; Atropine; Diazoxide; Epinephrine; Glucagon; Glucose; Glyburide; Heptoses; In Vitro Techniques; Insulin; Insulin Secretion; Isoproterenol; Ketoses; Norepinephrine; Pancreas; Parasympathomimetics; Perfusion; Phenoxybenzamine; Practolol; Propranolol; Sulfonylurea Compounds; Theophylline; Tolbutamide | 1974 |
Pancreatic blood flow and its relationship to insulin secretion during extracorporeal circulation.
Topics: Animals; Atropine; Dogs; Extracorporeal Circulation; Glucose; Insulin; Insulin Secretion; Isoproterenol; Pancreas; Regional Blood Flow; Secretory Rate; Tolbutamide | 1969 |
The role of sodium and potassium in insulin secretion from rabbit pancreas.
Topics: Animals; Atropine; Biological Transport, Active; Choline; Glucagon; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Leucine; Lithium; Ouabain; Pancreas; Potassium; Rabbits; Sodium; Tolbutamide | 1968 |
Control of pulsatile insulin secretion in man.
Topics: Adult; Aged; Atropine; Blood Glucose; Diabetes Mellitus; Female; Glucose; Humans; Insulin; Insulin Secretion; Kinetics; Male; Middle Aged; Naloxone; Phentolamine; Propranolol; Sodium Salicylate; Tolbutamide; Vagotomy | 1983 |
Characterization of the pancreatic polypeptide response to hypoglycemia in man.
Topics: Adult; Atropine; Glucose; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Kinetics; Male; Pancreatic Polypeptide; Tolbutamide | 1982 |
[Drug therapy of gastrointestinal motility disorders].
Topics: Antacids; Atropine; Carbenoxolone; Colonic Diseases, Functional; Deglutition Disorders; Diarrhea; Dumping Syndrome; Gastroesophageal Reflux; Gastrointestinal Motility; Humans; Intestinal Diseases; Metoclopramide; Propranolol; Tolbutamide | 1980 |
Effects of vitamins and common drugs on reduction of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in rat microsomes.
Topics: Adrenergic alpha-Agonists; Animals; Antioxidants; Atropine; Carcinogens; Cimetidine; Clonidine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Hypoglycemic Agents; Male; Microsomes, Liver; Muscarinic Antagonists; Nitrosamines; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Thioctic Acid; Tolbutamide; Vitamins | 2001 |
[ON ISLET CELL TUMOR].
Topics: Adenoma, Islet Cell; Atropine; Blood Chemical Analysis; Blood Glucose; Epinephrine; Neoplasms; Pancreatic Neoplasms; Pathology; Physiology; Prednisone; Surgical Procedures, Operative; Tolbutamide | 1964 |
[ON ISLET CELL TUMOR].
Topics: Adenoma, Islet Cell; Atropine; Blood Chemical Analysis; Blood Glucose; Epinephrine; Neoplasms; Pancreatic Neoplasms; Pathology; Physiology; Prednisone; Surgical Procedures, Operative; Tolbutamide | 1964 |