tolbutamide has been researched along with arginine in 157 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 118 (75.16) | 18.7374 |
1990's | 21 (13.38) | 18.2507 |
2000's | 12 (7.64) | 29.6817 |
2010's | 5 (3.18) | 24.3611 |
2020's | 1 (0.64) | 2.80 |
Authors | Studies |
---|---|
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Cerasi, E | 1 |
Horigome, K; Itabashi, H; Maruhama, Y; Oneda, A; Yanbe, A | 1 |
Cerasi, E; Gutzeit, A; Kikuchi, M; Rabinovitch, A; Renold, AE | 1 |
Charles, MA; Grodsky, GM; Lawecki, J; Steiner, AL | 1 |
Fallucca, F; Gambardella, S; Menzinger, G; Tamburrano, S | 1 |
Epstein, GH; Fanska, R; Grodsky, GM; Karam, JH | 1 |
Blizzard, RM; Huseman, C; Johanson, A; Varma, M | 1 |
Hudson, AJ; Tevaarwerk, GJ | 1 |
Gagliardino, JJ; Hernandez, RE; Rebolledo, OR; Zanetta, AC | 1 |
Altomonte, L; Bertoli, A; Ghirlanda, G; Greco, AV; Manna, R; Rebuzzi, AG | 1 |
Dunbar, JC; Foà, PP; Walsh, MF | 1 |
Cerasi, E; Efendić, S; Luft, R | 1 |
Hedo, JA; Marco, J; Villanueva, ML | 1 |
Nierle, C; Pfeiffer, EF; Schatz, H | 1 |
Baumeister, G; Stahl, M; Wagner, H | 1 |
Lerner, RL | 1 |
Botha, JL; Child, PT; Jackson, WP; Paul, M; Vinik, AI | 1 |
Parman, AU | 1 |
Chou, M; Diamond, D; Field, JB; Harding, PE; Mashiter, GD; Mashiter, K; Stout, J | 1 |
Ieiri, T; Kasai, K; Kikuchi, T; Shimoda, S; Takemura, Y | 1 |
Ogris, E; Swoboda, W; Turnheim, E | 1 |
Chiumello, G | 1 |
Guyda, HJ; Hoy, P; Tze, WJ | 1 |
Gilon, P; Henquin, JC | 1 |
Bertuzzi, F; Braghi, S; Davalli, AM; Di Carlo, V; Fattor, B; Pontiroli, AE; Pozza, G; Socci, C | 1 |
Ader, M; Bergman, RN; Bray, GA; Lee, A | 1 |
Cooper, GJ; Moore, CX | 1 |
Debuyser, A; Drews, G; Henquin, JC | 2 |
Kajiyama, S; Kanatsuna, T; Kano, Y; Kitagawa, Y; Kondo, M; Ludvigsson, J; Nakamura, N; Nakamura, Y; Nakano, K | 1 |
Marco, J; Miralles, P; Monge, L; Moreno, P; Silvestre, RA; Villanueva, ML | 1 |
Cerasi, E; Eylon, L; Nesher, R; Segal, N | 1 |
Ali, L; Hellman, B; Wesslén, N | 1 |
Rasmussen, H; Zawalich, KC; Zawalich, WS | 1 |
Rathanaswami, P; Sundaresan, R | 2 |
Cozzolino, D; Giugliano, D; Giunta, R; Salvatore, T; Torella, R | 1 |
Marco, J; Miralles, P; Moreno, P; Silvestre, RA; Villanueva, ML | 1 |
Bozem, M; Henquin, JC | 1 |
Lundquist, I | 1 |
Cattaneo, AG; Caviezel, F; Cetta, G; Pozza, G | 1 |
Amemiya, S; Asayama, K; Fujimoto, M; Higashida, K; Ichimura, K; Kato, K; Kusano, S; Ohyama, K | 1 |
Henquin, JC; Hermans, MP; Schmeer, W | 2 |
Curry, DL; Reaven, E; Safarik, RH | 1 |
Kikuchi, M | 1 |
Costin, G; Kogut, MD | 1 |
Wolff, G | 1 |
Ikeda, M | 2 |
Addah, SA; Crockford, PM; Powell, P | 1 |
Conn, JW; Fajans, SS; Floyd, JC; Harrison, TS; Knopf, RF; Thiffault, CA | 1 |
Deiss, WP; Ewer, RW | 1 |
Gorden, P; Roth, J | 1 |
Colwell, JA; Wilber, JF | 1 |
Ashworth, MA; Milner, RD | 1 |
Levey, GS; Mintz, DH; Schmidt, WM | 1 |
Freychet, P; Gorden, P; Kahn, R; Roth, J | 1 |
Cerasi, E; Widström, A | 1 |
Howell, SL; Montague, W | 1 |
Lefebvre, P; Luyckx, A | 1 |
Berson, SA; Goldsmith, SJ; Yalow, RS | 1 |
Chiba, M; Horigome, K; Itabashi, H; Matsuda, K; Ohneda, A; Sato, M; Yamagata, S | 1 |
Larkins, RG; Martin, FI | 1 |
Caccamo, A; Chiumello, G; Del Guercio, MJ; Devetta, M; Di Natale, B | 1 |
Blondel, B; Lambert, AE; Like, AA; Marliss, EB; Orci, L; Renold, AE; Stauffacher, W; Wollheim, CB | 1 |
Larkins, RG | 1 |
Bank, S; Jackson, WP; Kalk, WJ; Keller, P; Vinik, AI | 1 |
Cerasi, E; Luft, R | 1 |
Gerich, J; Grodsky, GM; Karam, J; Levin, S; Sando, H | 1 |
Cain, JP; Dluhy, RG; Williams, GH | 1 |
Kato, Y | 1 |
Fineberg, SE; Merimee, TJ | 1 |
Assan, R; Eschwege, E; Kopf, A; Tchobroutsky, G | 1 |
Alberti, KG; Hockaday, TD; Young, JD | 1 |
Blackard, WG; Kikuchi, M; Rabinovitch, A; Renold, AE | 1 |
Barbosa, J; Goetz, F; Kennedy, W; Nuttall, FQ | 1 |
Field, JB; Finster, JL; Mintz, DH; Raskin, P; Taylor, AL | 1 |
Edgar, P; Merimee, TJ; Rabinowitz, D | 1 |
Engel, WK; Goden, P; Griggs, RC; Nissley, SP; Roth, J | 1 |
Bricaire, H; Luton, JP; Modigliani, E; Strauch, G | 1 |
Hellerström, C; Schmidt, FH; Stork, H; Westman, S | 1 |
Balant, L; Burr, IM; Grodsky, GM; Renold, AE; Stauffacher, W | 1 |
Combourieu, M; Donnadieu, M; Schimpff, RM | 1 |
Ashcroft, SJ; Hedeskov, CJ; Randle, PJ | 1 |
Chao, KL; Cornblath, M; Kipnis, DM; Parker, ML; Pildes, RS | 1 |
Chez, RA; Horger, EO; Mintz, DH | 1 |
Fujimoto, WY; Williams, RH | 1 |
Underwood, LE; Van Wyk, JJ; Voina, SJ | 1 |
Corredor, DG; Danowski, TS; Mendelsohn, LV; Sabeh, G; Sunder, JH; Wasserman, RE | 1 |
Junod, A; Lambert, AE; Letarte, J; Stauffacher, W | 1 |
Yoshida, T | 1 |
Mahler, RJ; Szabo, O | 1 |
Chiumello, G; Quaglia, P; Schiavini, CA | 1 |
Basabe, JC; Lopez, NL; Viktora, JK; Wolff, FW | 1 |
Federspil, G; Frezzato, S; Macrì, C; Muggeo, M; Tiengo, A; Trisotto, A; Vianello, A | 1 |
Drash, A; Field, JB; Garces, LY; Kenny, FM; Mintz, D; Vazquez, AM | 1 |
Delzant, G; Modigliani, E; Strauch, G | 1 |
Bonner-Weir, S; Clore, ET; Weir, GC; Zmachinski, CJ | 1 |
Imura, H; Kuzuya, H; Sakurai, H; Seino, S; Seino, Y; Tsuda, K; Usami, M | 1 |
Blanc, N; Bosi, E; Dubernard, JM; Malik, MC; Pontiroli, AE; Pozza, G; Ruitton, A; Secchi, A; Traeger, J | 1 |
Brunetti, P; Filipponi, P; Marcelli, M; Nicoletti, I; Pacifici, R; Santeusanio, F | 1 |
Awoke, S; Bhathena, SJ; Gazdar, AF; Oie, HK; Recant, L; Voyles, NR; Wilkins, SD | 1 |
Hendriks, T; Jansen, JB; van Tongeren, JH | 1 |
Kobayashi, T; Nihei, J; Ohneda, A | 1 |
Kadowaki, S; Norman, AW | 1 |
Marliss, EB; Nakhooda, AF; Poussier, P | 2 |
Henquin, JC; Tamagawa, T | 1 |
Bailbe, D; Giroix, MH; Kergoat, M; Picon, L; Portha, B | 1 |
Bosi, E; Dubernard, JM; Gelet, A; Martin, X; Pontiroli, AE; Pozza, G; Secchi, A; Touraine, JL; Traeger, J | 1 |
Batista López, N; Bueno Gómez, J; González García, C; González Reimers, E; Hernández Nieto, L; Jorge Hernández, J; Pérez Labajos, P; Santolaria Fernández, F | 2 |
Beischer, W; Heinze, E; Teller, W; Thon, A; Vetter, U | 1 |
LeBlanc, J; Richard, D | 1 |
Brink, SJ; Eisenbarth, GS; Ganda, OP; Gleason, RE; Morris, MA; Soeldner, JS; Srikanta, S | 1 |
Beard, JC; Halter, JB; Judzewitsch, R; Pfeifer, MA; Porte, D | 1 |
Kobayashi, T; Nihei, J; Ohneda, A; Sakai, T | 1 |
Frankel, BJ; Freedman, ZR; Fujiya, H; Grodsky, GM; Karam, JH; Lewitt, PA; Nowlain, RE; Young, CW | 1 |
Batista López, N; Bueno Gómez, J; González García, C; González Reimers, E; Hernández Nieto, L; Jorge Hernández, J; Pestana Pestana, M; Santolaria Fernández, F | 1 |
Graf, R; Halter, JB; Pfeifer, MA; Porte, D | 1 |
Chapal, J; Lignon, F; Loubatières-Mariani, MM; Puech, R; Valette, G | 1 |
Casale, G; Ciaponi, A; Ferrero, E | 1 |
Kumahara, Y; Matsuyama, T; Sawazaki, N; Shima, K; Tanaka, R; Yanaihara, N | 1 |
Deng, LY; Li, JS; Schiffrin, EL | 1 |
Banitt, P; Creager, MA; Lipson, DE; Rongen, GA; Smits, P; Williams, SB | 1 |
Francini, F; Gagliardino, JJ | 1 |
Elks, ML | 1 |
Cohen, RA; Cowan, CL; Najibi, S; Palacino, JJ | 1 |
Ikuta, M; Kuhara, T; Oda, S; Ohneda, A; Sasaki, Y | 1 |
Gross, R; Hillaire-Buys, D; Manteghetti, M; Ribes, G; Roye, M | 1 |
Gilon, P; Henquin, JC; Lambillotte, C | 1 |
Hosaka, T; Oka, Y | 1 |
Broca, C; Gross, R; Hillaire-Buys, D; Manteghetti, M; Masiello, P; Novelli, M; Ribes, G; Roye, M | 1 |
Fineman, MS; Leahy, JL | 1 |
Yada, T; Yaekura, K; Yanagida, K | 1 |
Balamurugan, AN; Gunasekaran, S; Ramakrishna, B | 1 |
Krishnaiah, YS; Rao, BK; Satyanarayana, S | 1 |
Gelboin, HV; Goldfarb, I; Gonzalez, FJ; Krausz, KW; Yang, TJ | 1 |
Ball, AJ; Flatt, PR; McClenaghan, NH | 1 |
Arcangeli, A; Crociani, O; Lecchi, M; Lupi, R; Marchetti, P; Olivotto, M; Rosati, B; Wanke, E | 1 |
Aaen, K; Bock, T; Buschard, K; Hageman, I; Hansen, MW; Hansen, SV; Josefsen, K; Jørgensen, M; Kjaer, TW; Pedersen, CR | 1 |
AvRuskin, TW; Juan, CS | 1 |
Clapp, LH; Wilson, AJ | 1 |
Egido, EM; Hernández, R; Marco, J; Silvestre, RA | 1 |
Henquin, JC; Ishiyama, N; Ravier, MA | 1 |
Brennan, L; Flatt, PR; McClenaghan, NH; Newsholme, P; Patterson, S | 1 |
Brito, GA; Cunha, FQ; Ferreira, SH; Lotufo, CM; Ribeiro, RA; Sachs, D; Vale, ML | 1 |
Fukuda, S; Ishii, Y; Matsui, K; Matsushita, M; Miyajima, K; Nishizawa, E; Oda, T; Ohta, T; Sano, R; Sasase, T; Ueda, N; Yamamoto, H | 1 |
Allen, VL; Fowden, AL; Holdstock, NB; Jellyman, JK | 1 |
Eggert, F; Elgert, C; Früh, E; Rustenbeck, I; Scherneck, S | 1 |
Gasalla Chacón, R; Gónzalez Larriba, JL; Grande, C; Montero García, JM; Picaporte, MA | 1 |
7 review(s) available for tolbutamide and arginine
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Insulin secretion: mechanism of the stimulation by glucose.
Topics: Arginine; Calcium; Computers; Cyclic AMP; Diabetes Mellitus; Feedback; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Mathematics; Models, Biological; Tolbutamide | 1975 |
Pancreatic action of the sulfonylureas.
Topics: Animals; Arginine; Cyclic AMP; Dose-Response Relationship, Drug; Glucagon; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Sulfonylurea Compounds; Tolbutamide | 1977 |
[Hypoglycemia. 3].
Topics: Animals; Arginine; Biguanides; Diazoxide; Dicumarol; Drug Synergism; Ethanol; Glucagon; Glucocorticoids; Glucose; Guinea Pigs; Humans; Hypoglycemia; Hypoglycemic Agents; Leucine; Mice; Rabbits; Rats; Sympatholytics; Tolbutamide; Xylitol | 1970 |
Diabetes mellitus--a disease of pancreatic and extrapancreatic origin.
Topics: Amino Acids; Animals; Arginine; Blood Glucose; Calcium; Diabetes Mellitus; Dose-Response Relationship, Drug; Glucose; Glycerol; Growth Hormone; Humans; Insulin; Insulin Secretion; Kinetics; Models, Biological; Pancreas; Physical Exertion; Prediabetic State; Rats; Time Factors; Tolbutamide | 1974 |
Synthesis and secretion of insulin in dynamic perfusion systems.
Topics: Animals; Antimetabolites; Arginine; Carbon Radioisotopes; Computers; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Isotope Labeling; Leucine; Models, Biological; Obesity; Oligomycins; Pancreas; Perfusion; Rats; Time Factors; Tolbutamide | 1974 |
[Tolbutamide, glucagon, leucine and arginine tolerance test].
Topics: Arginine; Diabetes Mellitus; Glucagon; Humans; Hypoglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Pancreatic Function Tests; Tolbutamide | 1997 |
3 trial(s) available for tolbutamide and arginine
Article | Year |
---|---|
[Clinical investigations of the effect of tolbutamide and glibenclamide on pancreatic glucagon secretion (author's transl)].
Topics: Adult; Arginine; Blood Glucose; Glucagon; Glyburide; Humans; Insulin; Male; Pancreas; Tolbutamide | 1975 |
Influence of short-term lithium carbonate administration on stimulated insulin secretion in normal man.
Topics: Adult; Arginine; Blood Glucose; Electrolytes; Female; Glucose; Humans; Insulin; Insulin Secretion; Lithium; Lithium Carbonate; Male; Thyroid Function Tests; Time Factors; Tolbutamide | 1987 |
Glucocorticoid overexposure in neonatal life alters pancreatic beta-cell function in newborn foals.
Topics: Adrenocorticotropic Hormone; Animals; Animals, Newborn; Arginine; Blood Glucose; Horses; Insulin; Insulin-Secreting Cells; Tolbutamide | 2013 |
147 other study(ies) available for tolbutamide and arginine
Article | Year |
---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Diagnostic value of intravenous glucagon test in insulinoma.
Topics: Adenoma, Islet Cell; Adult; Aged; Arginine; Child; Evaluation Studies as Topic; Female; Glucagon; Glucose Tolerance Test; Humans; Injections, Intravenous; Middle Aged; Pancreatic Neoplasms; Tolbutamide | 1975 |
Defective early phase insulin release in perifused isolated pancreatic islets of spiny mice (Acomys cahirinus).
Topics: Age Factors; Animals; Arginine; Body Weight; Cyclic AMP; Cytochalasin B; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mice, Inbred C57BL; Mice, Obese; Perfusion; Rats; Species Specificity; Theophylline; Tolbutamide | 1975 |
Cyclic nucleotides in pancreatic islets. Tolbutamide- and arginine-induced insulin release.
Topics: Animals; Arginine; Cyclic AMP; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Rats; Tolbutamide | 1976 |
Response of islet cell tumors to enterohormones.
Topics: Adenoma, Islet Cell; Arginine; Blood Glucose; Cerulenin; Cholecystokinin; Gastrointestinal Hormones; Glucagon; Glucose Tolerance Test; Humans; Insulin; Pentagastrin; Secretin; Tolbutamide | 1976 |
Congenital lipodystrophy: An endocrine study in three siblings. I. Disorders of carbohydrate metabolism.
Topics: Adolescent; Adrenocorticotropic Hormone; Antigens; Arginine; Blood Glucose; Child; Child, Preschool; Female; Glucagon; Glucose Tolerance Test; Growth Hormone; Hormones; Humans; Infant; Insulin; Insulin Resistance; Insulin Secretion; Lipid Metabolism; Lipodystrophy; Male; Tolbutamide | 1978 |
Carbohydrate metabolism and insulin resistance in myotonia dystrophica.
Topics: Adult; Aged; Arginine; Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus; Female; Fructose; Galactose; Glucagon; Glucose Tolerance Test; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Leucine; Male; Middle Aged; Myotonic Dystrophy; Sorbitol; Tolbutamide; Xylose | 1977 |
Insulin secretion during acid-base alterations.
Topics: Acidosis; Alkalosis; Animals; Arginine; Female; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Perfusion; Rats; Tolbutamide | 1978 |
Early insulin and glucagon response to subsequent pulses of arginine, glucose, and tolbutamide in normal man.
Topics: Adolescent; Adult; Arginine; Blood Glucose; Dose-Response Relationship, Drug; Glucagon; Glucose; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Time Factors; Tolbutamide | 1979 |
Secretion of glucagon and insulin in hypophysectomized rats: effect of tolbutamide.
Topics: Animals; Arginine; Blood Glucose; Glucagon; Hypophysectomy; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Tolbutamide | 1979 |
Quantitative determination of the interaction between epinephrine and various insulin releasers in man.
Topics: Adult; Arginine; Dose-Response Relationship, Drug; Epinephrine; Female; Glucose; Humans; Insulin; Male; Middle Aged; Tolbutamide | 1978 |
Control of pancreatic polypeptide secretion by glucose in man.
Topics: Adult; Arginine; Blood Glucose; Female; Glucose; Humans; Hypoglycemia; Insulin; Male; Pancreatic Polypeptide; Tolbutamide | 1978 |
(Pro-) insulin biosynthesis and release of newly synthesized (pro-) insulin from isolated islets of rat pancreas in the presence of amino acids and sulphonylureas.
Topics: Amino Acids; Animals; Arginine; Glyburide; In Vitro Techniques; Insulin; Islets of Langerhans; Lysine; Male; Proinsulin; Rats; Sulfonylurea Compounds; Tolbutamide | 1975 |
The augmentation effects of secretin on the insulin responses to known stimuli: specificity for glucose.
Topics: Adult; Arginine; Blood Glucose; Glucagon; Glucose; Humans; Insulin; Isoproterenol; Kinetics; Male; Secretin; Tolbutamide | 1977 |
Pancreatic glucagon-like immunoreactivity in a pancreatectomized patient.
Topics: Antigens; Arginine; Blood Glucose; Epinephrine; Glucagon; Glucose Tolerance Test; Humans; Insulin; Kinetics; Male; Middle Aged; Pancreas; Pancreatectomy; Somatostatin; Tolbutamide | 1977 |
Effects of hypophysectomy and short-term growth hormone replacement on insulin release from and glucose metabolism in isolated rat islets of Langerhans.
Topics: Adrenal Glands; Animals; Arginine; Blood Urea Nitrogen; Body Weight; Butyrates; Cattle; Citrates; Eating; Glucose; Glycogen; Growth Hormone; Hypophysectomy; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Organ Size; Pancreas; Phosphates; Pituitary Gland; Rats; RNA; Serum Albumin; Time Factors; Tolbutamide; Xylitol | 1975 |
Persistent pancreatic glucagon but not insulin response to arginine in pancreatectomized dogs.
Topics: Animals; Arginine; Blood Glucose; Chromatography, Gel; Cross Reactions; Dogs; Femoral Artery; Glucagon; Immune Sera; Insulin; Pancreas; Pancreatectomy; Portal Vein; Radioimmunoassay; Stimulation, Chemical; Time Factors; Tolbutamide | 1975 |
[A low response of pituitary growth hormone secretion in the patient with diabetes mellitus after intravenous administration of L-dopa (author's transl)].
Topics: Adult; Antigens; Arginine; Blood Glucose; Diabetes Mellitus; Glucose Tolerance Test; Growth Hormone; Humans; Hyperthyroidism; Injections, Intravenous; Insulin; Levodopa; Middle Aged; Time Factors; Tolbutamide | 1975 |
[Results of the exercise (ergometer) test as a diagnostic screening procedure in children with short stature].
Topics: Adolescent; Arginine; Child; Diabetes Insipidus; Dwarfism, Pituitary; Exercise Test; Female; Glucagon; Growth Hormone; Humans; Hypoglycemia; Insulin; Male; Physical Stimulation; Pituitary Gland; Stimulation, Chemical; Tolbutamide | 1975 |
[Infantile diabetes].
Topics: Adolescent; Arginine; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Male; Tolbutamide | 1976 |
Provocative tests for growth hormone release.
Topics: Adolescent; Arginine; Glucagon; Growth Hormone; Humans; Hypoglycemia; Insulin; Male; Pituitary Function Tests; Tolbutamide | 1976 |
Influence of membrane potential changes on cytoplasmic Ca2+ concentration in an electrically excitable cell, the insulin-secreting pancreatic B-cell.
Topics: Animals; Arginine; Azides; Calcium; Cytosol; Diazoxide; Female; Glucose; In Vitro Techniques; Islets of Langerhans; Kinetics; Mannoheptulose; Membrane Potentials; Mice; Mice, Inbred Strains; NAD; NADP; Oscillometry; Potassium; Spectrometry, Fluorescence; Tolbutamide | 1992 |
Human islets chronically exposed in vitro to different stimuli become unresponsive to the same stimuli given acutely: evidence supporting specific desensitization rather than beta-cell exhaustion.
Topics: Arginine; Cells, Cultured; Dose-Response Relationship, Drug; Glucose; Humans; In Vitro Techniques; Insulin; Islets of Langerhans; Perfusion; Radioimmunoassay; Tolbutamide | 1992 |
Diurnal variation in glucose tolerance. Cyclic suppression of insulin action and insulin secretion in normal-weight, but not obese, subjects.
Topics: Adult; Arginine; Body Mass Index; Body Weight; Circadian Rhythm; Female; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Male; Obesity; Reference Values; Tolbutamide | 1992 |
Co-secretion of amylin and insulin from cultured islet beta-cells: modulation by nutrient secretagogues, islet hormones and hypoglycemic agents.
Topics: Amyloid; Animals; Arginine; Cell Line; Cricetinae; Glucagon; Glucose; Glyburide; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Islet Amyloid Polypeptide; Islets of Langerhans; Kinetics; Metformin; Somatostatin; Tolbutamide | 1991 |
Adrenaline inhibition of insulin release: role of the repolarization of the B cell membrane.
Topics: Animals; Arginine; Cell Membrane; Epinephrine; Female; Glucose; Insulin; Islets of Langerhans; Membrane Potentials; Mice; Tetraethylammonium; Tetraethylammonium Compounds; Tolbutamide | 1991 |
Islet cell surface antibodies preferentially inhibit glucose-stimulated insulin release in vitro.
Topics: Adolescent; Adult; Animals; Arginine; Autoantibodies; Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Glucose; Humans; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Middle Aged; Rats; Reference Values; Tolbutamide | 1990 |
Effects of galanin on hormone secretion from the in situ perfused rat pancreas and on glucose production in rat hepatocytes in vitro.
Topics: Animals; Arginine; Galanin; Glucagon; Gluconeogenesis; Glucose; Glycogen; In Vitro Techniques; Insulin; Insulin Secretion; Liver; Male; Pancreas; Pancreatic Hormones; Peptides; Rats; Rats, Inbred Strains; Somatostatin; Tolbutamide | 1987 |
Beta-cell memory to insulin secretagogues: characterization of the time-dependent inhibitory control system in the isolated rat pancreas.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Dose-Response Relationship, Drug; Epinephrine; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Rats; Time Factors; Tolbutamide | 1989 |
Effects of depolarizing agents on the sodium content of rat pancreatic islets.
Topics: Animals; Arginine; Islets of Langerhans; Membrane Potentials; Potassium; Rats; Rats, Inbred Strains; Sodium; Tolbutamide | 1989 |
Cholinergic agonists prime the beta-cell to glucose stimulation.
Topics: Animals; Arginine; Atropine; Carbachol; Drug Synergism; Glucose; In Vitro Techniques; Inositol; Inositol Phosphates; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Rats; Rats, Inbred Strains; Tolbutamide | 1989 |
Modulation of A and B cell functions by tolbutamide and arginine in the pancreas of thiamine-deficient rats.
Topics: Animals; Arginine; Blood Glucose; Glucagon; Insulin; Islets of Langerhans; Pancreas; Rats; Rats, Inbred Strains; Thiamine Deficiency; Tolbutamide | 1989 |
Theophylline prevents the inhibitory effect of prostaglandin E2 on glucose-induced insulin secretion in man.
Topics: Adult; Arginine; Blood Glucose; Cyclic AMP; Dinoprostone; Female; Glucose; Humans; Insulin; Insulin Secretion; Male; Prostaglandins E; Theophylline; Tolbutamide | 1988 |
Somatostatin, insulin and glucagon secretion by the perfused pancreas from the cysteamine-treated rat.
Topics: Animals; Arginine; Cysteamine; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Perfusion; Rats; Rats, Inbred Strains; Somatostatin; Tolbutamide | 1986 |
Effects of insulin secretagogues on the secretion of insulin during thiamine deficiency.
Topics: Animals; Arginine; Blood Glucose; Insulin; Insulin Secretion; Leucine; Rats; Rats, Inbred Strains; Thiamine Deficiency; Tolbutamide | 1988 |
Glucose modulation of spike activity independently from changes in slow waves of membrane potential in mouse B-cells.
Topics: Action Potentials; Animals; Arginine; Calcium; Female; Glucose; In Vitro Techniques; Islets of Langerhans; Mice; Ouabain; Tolbutamide | 1988 |
Islet amyloglucosidase activity: some characteristics, and its relation to insulin secretion stimulated by various secretagogues.
Topics: Animals; Arginine; Blood Glucose; Centrifugation; Fasting; Female; Glucagon; Glucan 1,4-alpha-Glucosidase; Glucocorticoids; Glucosidases; Glycogen; In Vitro Techniques; Insulin; Islets of Langerhans; Liver; Liver Glycogen; Maltose; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Inbred Strains; Octoxynol; Polyethylene Glycols; Tolbutamide | 1986 |
Residual pancreatic beta-cell function in insulin-dependent diabetes mellitus.
Topics: Adolescent; Arginine; Child; Child, Preschool; Diabetes Mellitus, Type 1; Glucagon; Glucose Tolerance Test; Humans; Islets of Langerhans; Tolbutamide | 1987 |
The permissive effect of glucose, tolbutamide and high K+ on arginine stimulation of insulin release in isolated mouse islets.
Topics: Animals; Arginine; Culture Techniques; Diazoxide; Female; Glucose; Glucose Solution, Hypertonic; Insulin; Islets of Langerhans; Membrane Potentials; Mice; Mice, Inbred Strains; Potassium; Rats; Tolbutamide | 1987 |
Effect of age on the insulin secretory response of perfused rat pancreas to arginine and tolbutamide.
Topics: Aging; Animals; Arginine; Body Weight; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Organ Size; Perfusion; Radioimmunoassay; Rats; Tolbutamide | 1987 |
Modulation of the effect of acetylcholine on insulin release by the membrane potential of B cells.
Topics: Acetylcholine; Animals; Arginine; Calcium Radioisotopes; Cell Membrane; Diazoxide; Female; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Membrane Potentials; Mice; Potassium; Radioisotopes; Rubidium; Tolbutamide | 1987 |
[Studies on kinetics of insulin secretion in perifused pancreatic islets of hamster. I. Characteristics of insulin secretory response to various secretagogues].
Topics: Animals; Arginine; Cricetinae; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Mesocricetus; Perfusion; Stimulation, Chemical; Tolbutamide | 1987 |
Carbohydrate intolerance in gonadal dysgenesis: evidence for insulin resistance and hyperglucagonemia.
Topics: Adolescent; Adult; Aging; Arginine; Blood Glucose; Body Weight; Child; Glucagon; Glucose Tolerance Test; Gonadal Dysgenesis; Growth Hormone; Humans; Insulin; Insulin Resistance; Malabsorption Syndromes; Male; Obesity; Tolbutamide | 1985 |
[Plasma insulin levels in endocrine diseases. 4. Effects of adrenergic receptor agents on plasma insulin levels].
Topics: Adolescent; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Arginine; Depression, Chemical; Epinephrine; Female; Humans; Insulin; Isoproterenol; Male; Methoxamine; Phenoxybenzamine; Phentolamine; Phenylephrine; Propranolol; Receptors, Adrenergic; Stimulation, Chemical; Sympatholytics; Sympathomimetics; Tolbutamide | 1973 |
Effect of sulfonylureas on the secretion of pancreatic immunoreactive glucagon and enteric glucagon-like immunoreactivity.
Topics: Animals; Antibody Formation; Antigens; Arginine; Glucagon; Glucose; Glyburide; In Vitro Techniques; Insulin Antibodies; Pancreas; Radioimmunoassay; Rats; Sulfonylurea Compounds; Theophylline; Tolbutamide | 1973 |
Further studies on diazoxide suppression of insulin release from abnormal and normal islet tissue in man.
Topics: Adenoma, Islet Cell; Arginine; Blood Glucose; Catecholamines; Depression, Chemical; Diazoxide; Female; Glucagon; Glucose; Humans; Hyperglycemia; Hyperinsulinism; Hypoglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Tolbutamide; Trichlormethiazide | 1968 |
Clinical experience with human growth hormone immunoassay by a two-antibody method.
Topics: Acromegaly; Adenoma, Chromophobe; Adenoma, Islet Cell; Amenorrhea; Anorexia Nervosa; Arginine; Dwarfism; Female; Growth Hormone; Humans; Hypoglycemia; Iodine Isotopes; Lactation; Male; Obesity; Pancreatic Neoplasms; Physical Exertion; Pituitary Neoplasms; Pregnancy; Radioimmunoassay; Tolbutamide | 1969 |
Plasma insulin: fluctuations in the "big" insulin component in man after glucose and other stimuli.
Topics: Acromegaly; Adenoma, Islet Cell; Adolescent; Adult; Arginine; Fasting; Female; Glucose; Glucose Tolerance Test; Humans; Immunoassay; Insulin; Iodine Isotopes; Male; Middle Aged; Obesity; Pancreatic Neoplasms; Thinness; Tolbutamide | 1969 |
Studies of insulin and growth hormone secretion in a subject with hepatoma and gypoglycemia.
Topics: Adipose Tissue; Adult; Animals; Arginine; Blood Glucose; Carcinoma, Hepatocellular; Dexamethasone; Fatty Acids, Nonesterified; Glucagon; Gluconeogenesis; Glucose; Glucose Tolerance Test; Glycogen Storage Disease; Growth Hormone; Humans; Hypoglycemia; Insulin; Insulin Secretion; Lactates; Liver Neoplasms; Male; Muscles; Phentolamine; Phosphates; Rats; Tolbutamide | 1971 |
Insulin release from human fetal pancreas in vitro.
Topics: Arginine; Barium; Body Weight; Cyclic AMP; Female; Fetus; Gestational Age; Glucagon; Glucose; Humans; In Vitro Techniques; Insulin; Insulin Secretion; Leucine; Ouabain; Pancreas; Potassium; Pregnancy; Theophylline; Tolbutamide | 1971 |
Activation of adenyl cyclase in a pancreatic islet cell adenoma by glucagon and tolbutamide.
Topics: Adenoma, Islet Cell; Adenosine Triphosphate; Adenylyl Cyclases; Administration, Oral; Arginine; Blood Glucose; Cyclic AMP; Enzyme Activation; Fasting; Fluorides; Glucagon; Glucose; Humans; Hypoglycemia; In Vitro Techniques; Injections, Intravenous; Insulin; Insulin Secretion; Leucine; Male; Middle Aged; Phosphorus Isotopes; Tolbutamide | 1972 |
The circulating proinsulin-like components.
Topics: Adenoma, Islet Cell; Arginine; Chromatography, Gel; Glucagon; Glucose; Half-Life; Humans; Insulin; Proinsulin; Tolbutamide | 1972 |
On the action of tolbutamide in normal man. 3. Interaction of tolbutamide with glucagon, aminophylline and arginine in stimulating insulin response.
Topics: Adenylyl Cyclases; Adult; Aminophylline; Arginine; Blood Glucose; Cyclic AMP; Drug Interactions; Drug Synergism; Female; Glucagon; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Middle Aged; Phosphodiesterase Inhibitors; Tolbutamide | 1973 |
The mode of action of adenosine 3':5'-cyclic monophosphate in mammalian islets of Langerhans. Effects of insulin secretagogues on islet-cell protein kinase activity.
Topics: Animals; Arginine; Caffeine; Cyclic AMP; Diazoxide; Epinephrine; Glucagon; Glyburide; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Phosphorus Isotopes; Phosphotransferases; Protein Kinases; Rats; Theophylline; Time Factors; Tolbutamide; Xanthines; Xylitol | 1973 |
[Exploration of hypoglycemia].
Topics: Adenoma, Islet Cell; Arginine; Blood Glucose; Diazoxide; Diet; Fasting; Glucagon; Hormones, Ectopic; Humans; Hypoglycemia; Insulin; Insulin Secretion; Leucine; Medical History Taking; Pancreatic Neoplasms; Physical Examination; Time Factors; Tolbutamide | 1974 |
Effects of 2-deoxy-D-glucose on insulin-secretory responses to intravenous glucose, glucagon, tolbutamide and arginine in man.
Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Adult; Animals; Arginine; Blood Glucose; Diabetes Mellitus; Epinephrine; Glucagon; Glucose; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Secretory Rate; Stimulation, Chemical; Swine; Tolbutamide | 1970 |
Suppression of pancreatic glucagon secretion by tolbutamide in dogs.
Topics: Animals; Arginine; Blood Glucose; Dogs; Glucagon; Insulin; Pancreas; Time Factors; Tolbutamide | 1974 |
Selective defect in insulin release in one form of spontaneous laboratory diabetes.
Topics: Animals; Animals, Laboratory; Arginine; Diabetes Mellitus; Fasting; Glucagon; Glucose; Insulin; Mice; Radioimmunoassay; Stimulation, Chemical; Time Factors; Tolbutamide | 1972 |
B-pancreatic function in obese and diabetic children.
Topics: Arginine; Blood Glucose; Child; Diabetes Mellitus, Type 1; Ethylenediamines; Female; Glucagon; Glucose Tolerance Test; Humans; Injections, Intravenous; Insulin; Islets of Langerhans; Male; Obesity; Theophylline; Tolbutamide | 1972 |
Insulin and glucagon release from monolayer cell cultures of pancreas from newborn rats.
Topics: Alanine; Animals; Animals, Newborn; Arginine; Calcium; Cells, Cultured; Diazoxide; Epinephrine; Glucagon; Glucose; Heptoses; Insulin; Islets of Langerhans; Mannose; Ouabain; Pancreas; Potassium; Rats; Tolbutamide | 1973 |
Defective insulin secretion in the N.Z.O. mouse: in vitro studies.
Topics: Animals; Arginine; Blood; Blood Glucose; Epinephrine; Glucagon; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mice, Inbred Strains; Theophylline; Tolbutamide | 1973 |
Selective loss of beta cell response to glucose in chronic pancreatitis.
Topics: Administration, Oral; Antigens; Arginine; Cholecystokinin; Chronic Disease; Glucagon; Glucose; Humans; Injections, Intravenous; Insulin; Insulin Secretion; Islets of Langerhans; Pancreatitis; Secretin; Time Factors; Tolbutamide | 1974 |
Glucagon-initiated human growth hormone release: a comparative study.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Aged; Arginine; Blood Glucose; Fatty Acids, Nonesterified; Female; Glucagon; Gonadotropins; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Hypopituitarism; Insulin; Male; Metyrapone; Middle Aged; Radioimmunoassay; Sella Turcica; Stimulation, Chemical; Thyroxine; Tolbutamide | 1972 |
[Secretion of human growth hormone (HGH). 1. Basic study of HGH determination and serum HGH in normal subjects].
Topics: Acromegaly; Adult; Animals; Antibodies; Arginine; Blood Glucose; Female; Glucose Tolerance Test; Growth Hormone; Guinea Pigs; Humans; Insulin; Iodine Isotopes; Male; Methods; Middle Aged; Radioimmunoassay; Tolbutamide | 1972 |
Pancreatic compartmentalization of insulin. Evidence for pituitary control.
Topics: Arginine; Blood Glucose; Dietary Proteins; Dwarfism; Glucagon; Glucose Tolerance Test; Growth Hormone; Humans; Injections, Intravenous; Insulin; Insulin Secretion; Pancreas; Pituitary Gland; Stimulation, Chemical; Tolbutamide | 1973 |
Serial postprandial plasma insulin levels in 117 subjects with and without diabetes.
Topics: Adolescent; Adult; Aged; Arginine; Blood Glucose; Diabetes Mellitus; Eating; Humans; Insulin; Middle Aged; Obesity; Time Factors; Tolbutamide | 1973 |
Werner's syndrome: metabolic observations.
Topics: Adult; Arginine; Blood Glucose; Collagen Diseases; Female; Glucose Tolerance Test; Humans; Insulin; Lactates; Pyruvates; Tolbutamide; Werner Syndrome | 1974 |
Perifusion of pancreas fragments. A system for the study of dynamic aspects of insulin secretion.
Topics: Alanine; Animals; Arginine; Culture Media; Fructose; Galactose; Glucose; Glycolysis; Hydrogen-Ion Concentration; In Vitro Techniques; Insulin; Insulin Antibodies; Insulin Secretion; Iodine Radioisotopes; Leucine; Male; Mannose; Methods; Pancreas; Perfusion; Rats; Ribose; Time Factors; Tolbutamide; Xylitol | 1974 |
Plasma insulin in patients with myotonic dystrophy and their relatives.
Topics: Adolescent; Adult; Aged; Amino Acids; Antigens; Arginine; Child; Child, Preschool; Electromyography; Female; Glucagon; Glucose Tolerance Test; Heterozygote; Humans; Hyperinsulinism; Insulin; Leucine; Male; Middle Aged; Muscles; Myotonic Dystrophy; Tolbutamide | 1974 |
Pituitary apoplexy in acromegaly.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acromegaly; Adult; Arginine; Blood; Blood Glucose; Diabetes Complications; Female; Glucose Tolerance Test; Growth Hormone; Hemorrhage; Humans; Hydrocortisone; Insulin; Islets of Langerhans; Necrosis; Osmolar Concentration; Pituitary Diseases; Thyroxine; Tolbutamide; Urine | 1968 |
Effects of amino acids on insulin release from excised rabbit pancreas.
Topics: Amino Acids; Animals; Arginine; Epinephrine; Glucose; Histidine; In Vitro Techniques; Insulin; Insulin Antagonists; Insulin Secretion; Islets of Langerhans; Leucine; Lysine; Rabbits; Stimulation, Chemical; Tolbutamide | 1969 |
Studies of plasma insulin in myotonic dystrophy.
Topics: Adolescent; Adult; Arginine; Blood Glucose; Child; Chromatography, Gel; Female; Glucose Tolerance Test; Humans; Insulin; Islets of Langerhans; Male; Myotonic Dystrophy; Tolbutamide | 1969 |
Partial somatotrophin insufficiency in Cushing's syndrome.
Topics: Adult; Arginine; Cushing Syndrome; Female; Glucose Tolerance Test; Growth Hormone; Humans; Hypoglycemia; Male; Middle Aged; Pituitary Hormone-Releasing Hormones; Radioimmunoassay; Tolbutamide | 1969 |
[Effect of blood sugar decreasing sulfonylureas on the in vitro metabolism of glucose and amino acids in the beta-cells of the pancreas in mice].
Topics: Alanine; Amino Acids; Animals; Arginine; Carbon Isotopes; Depression, Chemical; Female; Glucose; Hyperglycemia; Hypoglycemic Agents; In Vitro Techniques; Insulin; Islets of Langerhans; Leucine; Male; Mice; Obesity; Oxidation-Reduction; Oxygen Consumption; Pancreas; Stimulation, Chemical; Tolbutamide; Urea; Valine | 1969 |
[Regulation of insulin release in perifused pancreatic tissue].
Topics: Amino Acids; Animals; Aprotinin; Arginine; Freezing; Glucagon; Glucose; Hypoglycemic Agents; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Pancreas; Perfusion; Rats; Sulfonamides; Tolbutamide | 1969 |
[Radio-immunologic determination of the human plasma growth hormone (S.T.H.). Contribution of the stimulation tests by arginine and insulin in the delimitation of a pituitary insufficiency].
Topics: Adolescent; Adult; Arginine; Child; Child, Preschool; Female; Growth; Growth Disorders; Growth Hormone; Humans; Hypoglycemia; Hypopituitarism; Infant; Insulin; Male; Statistics as Topic; Tolbutamide | 1970 |
Glucose metabolism in mouse pancreatic islets.
Topics: Animals; Arginine; Cycloheximide; Diazoxide; Epinephrine; Fructose; Glucagon; Glucosamine; Glucose; Hexosephosphates; Hexoses; In Vitro Techniques; Islets of Langerhans; Lactates; Mannose; Mice; Monosaccharides; Phlorhizin; Tolbutamide | 1970 |
Juvenile diabetes mellitus, a deficiency in insulin.
Topics: Arginine; Child; Diabetes Mellitus, Type 1; Glucose; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Reference Values; Tolbutamide | 1968 |
Fetal insulin and growth hormone metabolism in the subhuman primate.
Topics: Animals; Arginine; Blood Glucose; Female; Glucose; Growth Hormone; Haplorhini; Immune Sera; Insulin; Iodine Radioisotopes; Islets of Langerhans; Maternal-Fetal Exchange; Pancreas; Pituitary Gland; Pregnancy; Tolbutamide | 1969 |
Insulin release from cultured fetal human pancreas.
Topics: Arginine; Culture Media; Drug Synergism; Fetus; Gestational Age; Glucose; Humans; Insulin; Insulin Secretion; Organ Culture Techniques; Pancreas; Radioimmunoassay; Stimulation, Chemical; Theophylline; Tolbutamide | 1972 |
[Plasma insulin levels in endocrine diseases. I. Plasma insulin levels in normal subjects and diabetic patients].
Topics: Administration, Oral; Adolescent; Adult; Arginine; Blood Glucose; Diabetes Mellitus; Glucagon; Glucose; Glucose Tolerance Test; Humans; Injections, Intravenous; Insulin; Iodine Isotopes; Radioimmunoassay; Tolbutamide | 1971 |
Failure of leucine, arginine, and epinephrine to alter plasma insulin levels in vitro.
Topics: Animals; Antigen-Antibody Reactions; Arginine; Depression, Chemical; Epinephrine; Guinea Pigs; Humans; Insulin; Insulin Antibodies; Iodine Isotopes; Leucine; Radioimmunoassay; Stimulation, Chemical; Swine; Tolbutamide | 1971 |
Enhanced postglucose hypophosphatemia during starvation therapy of obesity.
Topics: Adolescent; Adult; Arginine; Blood Glucose; Body Weight; Depression, Chemical; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Glucose Tolerance Test; Growth Hormone; Humans; Hyperglycemia; Insulin; Liver; Middle Aged; Muscles; Obesity; Phosphorus; Stimulation, Chemical; Time Factors; Tolbutamide | 1969 |
Studies in spiny mice (Acomys cahirinus): metabolic state and pancreatic insulin release in vitro.
Topics: Age Factors; Animals; Antigens; Arginine; Blood Glucose; Caffeine; Calcium; Diabetes Mellitus; Glucagon; Glycosuria; Hyperglycemia; In Vitro Techniques; Insulin; Insulin Secretion; Leucine; Mice; Mice, Inbred Strains; Obesity; Pancreas; Tolbutamide | 1969 |
[Clinical studies on the immunoreactive insulin. II. The immunoreactive insulin (IRI) in normal subjects and patients with diabets mellitus and other endocrinopathy].
Topics: Acromegaly; Adolescent; Adult; Aged; Anemia, Aplastic; Arginine; Child; Child, Preschool; Circadian Rhythm; Diabetes Mellitus; Dwarfism, Pituitary; Endocrine System Diseases; Female; Gastrectomy; Glucose Tolerance Test; Humans; Hyperthyroidism; Infant; Infant, Newborn; Insulin; Male; Mental Disorders; Middle Aged; Prednisolone; Radioimmunoassay; Tolbutamide | 1970 |
The effects of epinephrine, amino acids and albumin on the measurement of insulin by radioimmunoassay.
Topics: Animals; Antigen-Antibody Reactions; Antigens; Arginine; Binding Sites; Chemical Phenomena; Chemistry; Diazoxide; Epinephrine; Evaluation Studies as Topic; Glucose; Glucose Tolerance Test; Guinea Pigs; Humans; Immune Sera; Insulin; Insulin Antibodies; Iodine Isotopes; Leucine; Methods; Protein Binding; Radioimmunoassay; Serum Albumin; Swine; Tolbutamide | 1970 |
[On a case of diabetes mellitus with unusual evolution].
Topics: Adolescent; Arginine; Blood Glucose; Child; Diabetes Mellitus, Type 1; Female; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin; Tolbutamide | 1971 |
Insulin secretion studied in the perfused rat pancreas. I. Effect of tolbutamide, leucine and arginine; their interaction with diazoxide, and relation to glucose.
Topics: Animals; Arginine; Buffers; Diazoxide; Glucose; Insulin; Insulin Secretion; Leucine; Male; Pancreas; Perfusion; Radioimmunoassay; Rats; Stimulation, Chemical; Tolbutamide | 1971 |
[Functional exploration of insulin secretion in sponteaneous hypoglycemia].
Topics: Adenoma; Arginine; Glucagon; Glucose; Humans; Hyperinsulinism; Hypoglycemia; Insulin; Insulin Secretion; Leucine; Pancreas; Pancreatic Neoplasms; Tolbutamide | 1967 |
Endogenous insulin and growth hormone response in children with newly diagnosed diabetes mellitus.
Topics: Adolescent; Arginine; Carbon Dioxide; Child; Child, Preschool; Chlorides; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Growth Hormone; Humans; Hydrogen; Infant; Insulin; Insulin Secretion; Male; Partial Pressure; Potassium; Sodium; Stimulation, Chemical; Tolbutamide | 1968 |
[Insulin secretion study during arginine perfusion. Comparative effects of sympatholytics in normal subjects and hyperthyroid patients].
Topics: Adult; Aged; Arginine; Blood Glucose; Catecholamines; Diabetes Complications; Epinephrine; Glucose; Guanethidine; Humans; Hyperthyroidism; Insulin; Insulin Secretion; Middle Aged; Perfusion; Phentolamine; Propranolol; Proteins; Radioimmunoassay; Thyroid Hormones; Tolbutamide | 1969 |
Islet secretion in a new experimental model for non-insulin-dependent diabetes.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Isoproterenol; Male; Pregnancy; Rats; Somatostatin; Theophylline; Tolbutamide | 1981 |
Glucose regulation of arginine-induced pancreatic somatostatin release from the isolated perfused rat pancreas.
Topics: Animals; Arginine; Dose-Response Relationship, Drug; Glucagon; Glucose; Insulin; Male; Pancreas; Rats; Rats, Inbred Strains; Somatostatin; Tolbutamide | 1982 |
Endocrine responses of type 1 (insulin-dependent) diabetic patients following successful pancreas transplantation.
Topics: Adult; Arginine; Diabetes Mellitus; Female; Glucagon; Glucose Tolerance Test; Growth Hormone; Humans; Insulin; Kidney Transplantation; Male; Middle Aged; Pancreas Transplantation; Somatostatin; Tolbutamide | 1983 |
Suppressive effect of long term sulfonylurea treatment on A, B, and D cells of normal rat pancreas.
Topics: Animals; Arginine; Glucagon; Glucose; Glyburide; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Rats, Inbred Strains; Somatostatin; Time Factors; Tolbutamide | 1983 |
Insulin, glucagon, and somatostatin secretion by cultured rat islet cell tumor and its clones.
Topics: Adenoma, Islet Cell; Animals; Arginine; Calcium; Clone Cells; Glucagon; Glucose; Insulin; Potassium; Rats; Somatostatin; Theophylline; Tolbutamide | 1984 |
The glucagonoma syndrome: stimulus-induced plasma responses of circulating glucagon components IRG9000 and IRG3500.
Topics: Adenoma, Islet Cell; Arginine; Calcitonin; Calcium; Chromatography, Gel; Fasting; Female; Glucagon; Glucagonoma; Humans; Middle Aged; Molecular Weight; Pancreatic Neoplasms; Radioimmunoassay; Somatostatin; Tolbutamide | 1984 |
Plasma insulin response to various secretagogues in insulinoma.
Topics: Adenoma, Islet Cell; Adult; Aged; Arginine; Blood Glucose; Child; Fasting; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulinoma; Male; Middle Aged; Pancreatic Neoplasms; Radioimmunoassay; Tolbutamide | 1982 |
Dietary vitamin D is essential for normal insulin secretion from the perfused rat pancreas.
Topics: Animals; Arginine; Calcium; Calcium, Dietary; Cholecalciferol; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Male; Pancreas; Rats; Tolbutamide; Vitamin D Deficiency | 1984 |
Insulin and glucagon secretion in BB wistar rats with impaired glucose tolerance.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus; Female; Glucagon; Glucose; Glucose Tolerance Test; Insulin; Insulin Secretion; Kinetics; Male; Rats; Rats, Inbred Strains; Tolbutamide | 1983 |
Chloride modulation of insulin release, 86Rb+ efflux, and 45Ca2+ fluxes in rat islets stimulated by various secretagogues.
Topics: Animals; Arginine; Calcium; Chlorides; Exocytosis; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Rats; Rats, Inbred Strains; Rubidium; Theophylline; Tolbutamide | 1983 |
Glucose insensitivity and amino-acid hypersensitivity of insulin release in rats with non-insulin-dependent diabetes. A study with the perfused pancreas.
Topics: Acetylcholine; Amino Acids; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Glucose; Glyceraldehyde; Insulin; Insulin Secretion; Islets of Langerhans; Isoproterenol; Keto Acids; Leucine; Mannose; Rats; Rats, Inbred Strains; Theophylline; Tolbutamide | 1983 |
Functional study of insulin secretion pattern following segmental neoprene-injected pancreatic allograft in insulin-dependent (type 1) diabetic recipients.
Topics: Adult; Arginine; Cyclosporins; Diabetes Mellitus, Type 1; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Neoprene; Pancreas Transplantation; Polyenes; Tolbutamide | 1983 |
Clinical forms and natural history of the diabetic syndrome and insulin and glucagon secretion in the BB rat.
Topics: Animals; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Female; Glucagon; Insulin; Insulin Secretion; Male; Rats; Rats, Inbred Strains; Stress, Physiological; Tolbutamide | 1983 |
[Changes in carbohydrate metabolism in liver cirrhosis. V. Dynamics of insulin secretion].
Topics: Adolescent; Adult; Aged; Arginine; Carbohydrate Metabolism; Diabetes Mellitus; Female; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Liver Cirrhosis; Male; Middle Aged; Tolbutamide | 1983 |
The effect of glucose, tolbutamide, and arginine on C-peptide release during remission in type I diabetes mellitus.
Topics: Adolescent; Arginine; C-Peptide; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Glucose; Humans; Insulin; Male; Tolbutamide | 1983 |
Pancreatic insulin response in relation to exercise training.
Topics: Animals; Arginine; Female; Insulin; Insulin Secretion; Islets of Langerhans; Physical Exertion; Rats; Secretory Rate; Tolbutamide | 1983 |
Differential sensitivity to beta-cell secretagogues in "early," type I diabetes mellitus.
Topics: Arginine; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Tolbutamide | 1984 |
Insulin responses to nonglucose stimuli in non-insulin-dependent diabetes mellitus during a tolbutamide infusion.
Topics: Adult; Aged; Arginine; Blood Glucose; Diabetes Mellitus; Glucose; Humans; Insulin; Insulin Secretion; Isoproterenol; Male; Middle Aged; Tolbutamide | 1982 |
Analysis of insulin secretion based on changes in plasma insulin and C-peptide in man.
Topics: Adult; Aged; Arginine; C-Peptide; Diabetes Mellitus; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Liver Cirrhosis; Male; Middle Aged; Nephritis; Pancreatic Neoplasms; Peptides; Tolbutamide | 1982 |
Insulinopenic diabetes after rodenticide (Vacor) ingestion: a unique model of acquired diabetes in man.
Topics: Adult; Arginine; Blood Glucose; C-Peptide; Child; Diabetes Mellitus; Diabetic Ketoacidosis; Diabetic Neuropathies; Glucagon; Glucose Tolerance Test; Humans; Insulin; Islets of Langerhans; Male; Phenylurea Compounds; Tolbutamide | 1980 |
[Changes in carbohydrate metabolism in liver cirrhosis. I. Carbohydrate intolerance].
Topics: Adolescent; Adult; Aged; Arginine; Blood Glucose; Carbohydrate Metabolism; Diabetes Complications; Female; Glucose Tolerance Test; Humans; Liver Cirrhosis; Male; Middle Aged; Tolbutamide | 1983 |
[Changes in hydrocarbon metabolism in hepatic cirrhosis. VI. HGH].
Topics: Adolescent; Adult; Aged; Arginine; Diabetes Mellitus; Female; Glucose Tolerance Test; Growth Hormone; Humans; Liver Cirrhosis; Male; Middle Aged; Tolbutamide | 1983 |
Potentiation of insulin secretion to nonglucose stimuli in normal man by tolbutamide.
Topics: Arginine; Blood Glucose; Drug Synergism; Glucose; Humans; Infusions, Parenteral; Insulin; Insulin Secretion; Islets of Langerhans; Isoproterenol; Male; Regression Analysis; Tolbutamide | 1980 |
Different effects of hypothermia on insulin and glucagon secretion from the isolated perfused rat pancreas.
Topics: Acetylcholine; Animals; Arginine; Glucagon; Glucose; Hypothermia, Induced; Insulin; Insulin Secretion; Pancreas; Perfusion; Rats; Tolbutamide | 1980 |
[Exhaustibility of beta cells in the aged after repeated stimuli].
Topics: Adult; Age Factors; Aged; Arginine; Glucagon; Glucose; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Tolbutamide | 1980 |
Failure of exogenous insulin to inhibit C-peptide release from the perfused rat pancreas.
Topics: Animals; Arginine; C-Peptide; Glucagon; Glucose; Insulin; Male; Pancreas; Peptides; Perfusion; Rats; Tolbutamide | 1980 |
Significance of membrane repolarization and cyclic AMP changes in mouse pancreatic B-cells for the inhibition of insulin release by galanin.
Topics: Adenylyl Cyclases; Animals; Arginine; Bucladesine; Calcium; Cell Membrane; Cyclic AMP; Cytochalasin B; Female; Galanin; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Membrane Potentials; Mice; Peptides; Second Messenger Systems; Tolbutamide | 1994 |
Endothelium-dependent relaxation of small arteries from essential hypertensive patients: mechanisms and comparison with normotensive subjects and with responses of vessels from spontaneously hypertensive rats.
Topics: Acetylcholine; Adult; Animals; Apamin; Arginine; Arterioles; Charybdotoxin; Endothelium, Vascular; Humans; Hypertension; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Middle Aged; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Ouabain; Potassium Chloride; Rats; Rats, Inbred SHR; Scorpion Venoms; Tolbutamide; Vasoconstriction | 1995 |
Endothelial release of nitric oxide contributes to the vasodilator effect of adenosine in humans.
Topics: Adenosine; Arginine; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Female; Forearm; Humans; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Plethysmography; Potassium Channels; Quinidine; Regional Blood Flow; Tolbutamide; Vasodilation; Vasodilator Agents; Verapamil | 1995 |
An in vitro model suitable for studying insulin secretion in amphibians.
Topics: Acetylcholine; Amphibians; Animals; Arginine; Bufo arenarum; Caproates; Glucagon; Glucose; In Vitro Techniques; Insulin; Insulin Antagonists; Insulin Secretion; Keto Acids; Male; Nifedipine; Pancreatin; Potassium; Radioimmunoassay; Somatostatin; Swine; Tolbutamide | 1995 |
Chronic perifusion of rat islets with palmitate suppresses glucose-stimulated insulin release.
Topics: Animals; Arginine; Epoxy Compounds; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Oxidation-Reduction; Palmitic Acid; Palmitic Acids; Perfusion; Propionates; Rats; Rats, Wistar; Stearic Acids; Tolbutamide | 1993 |
Potassium channel-mediated relaxation to acetylcholine in rabbit arteries.
Topics: Acetylcholine; Animals; Aorta, Abdominal; Aorta, Thoracic; Arginine; Cyclic GMP; Endothelium, Vascular; Glyburide; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Potassium; Potassium Channels; Rabbits; Stimulation, Chemical; Tetraethylammonium; Tetraethylammonium Compounds; Tolbutamide | 1993 |
Insulin and glucagon secretion in goats (Capra hircus Linnaeus) exposed to cold.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Arginine; Butyrates; Butyric Acid; Cold Temperature; Female; Glucagon; Glucose; Goats; Infusions, Intravenous; Insulin; Insulin Secretion; Phentolamine; Propranolol; Tolbutamide | 1995 |
Alterations of insulin response to different beta cell secretagogues and pancreatic vascular resistance induced by N omega-nitro-L-arginine methyl ester.
Topics: Analysis of Variance; Animals; Arginine; Drug Interactions; Glucose; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Pancreas; Potassium Chloride; Rats; Rats, Wistar; Stereoisomerism; Tolbutamide; Vascular Resistance; Vasoconstriction; Vasodilator Agents | 1995 |
Direct glucocorticoid inhibition of insulin secretion. An in vitro study of dexamethasone effects in mouse islets.
Topics: Animals; Arginine; B-Lymphocytes; Bucladesine; Calcium; Cells, Cultured; Cyclic AMP; Dexamethasone; Dose-Response Relationship, Drug; Glucocorticoids; Glucose; Inositol Phosphates; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred Strains; NADP; Oxidation-Reduction; Pertussis Toxin; Phorbol Esters; Potassium; Receptors, Glucocorticoid; Tolbutamide; Virulence Factors, Bordetella | 1997 |
Experimental NIDDM: development of a new model in adult rats administered streptozotocin and nicotinamide.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucose; Glucose Tolerance Test; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Niacinamide; Rats; Rats, Wistar; Streptozocin; Tolbutamide | 1998 |
Impaired phasic insulin and amylin secretion in diabetic rats.
Topics: Activity Cycles; Amyloid; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Glucose; Hypoglycemic Agents; Insulin; Insulin Secretion; Islet Amyloid Polypeptide; Islets of Langerhans; Male; Pancreatectomy; Rats; Rats, Sprague-Dawley; Tolbutamide | 1998 |
PACAP and GLP-1 protect islet beta-cells against Ca2+ toxicity induced by high K+.
Topics: Animals; Arginine; Calcium; Cells, Cultured; Glucagon; Glucagon-Like Peptide 1; Glucose; Islets of Langerhans; Neuropeptides; Nifedipine; Peptide Fragments; Pituitary Adenylate Cyclase-Activating Polypeptide; Potassium Chloride; Protein Precursors; Rats; Rats, Wistar; Tolbutamide | 1998 |
Optimization of culture conditions for the preservation of monkey pancreatic islets in culture.
Topics: Animals; Arginine; Cell Culture Techniques; Cell Separation; Cell Survival; Cells, Cultured; Female; Glucose; Insulin; Islets of Langerhans; Leucine; Macaca radiata; Male; Tolbutamide | 1999 |
Involvement of nitric oxide (NO) in hypoglycaemic activity of tolbutamide.
Topics: Animals; Arginine; Blood Glucose; Female; Hypoglycemia; Hypoglycemic Agents; Male; Nitric Oxide; Rabbits; Tolbutamide | 1998 |
An inhibitory monoclonal antibody to human cytochrome P450 that specifically binds and inhibits P4502C9II, an allelic variant of P4502C9 having a single amino acid change Arg144 Cys.
Topics: Alleles; Amino Acid Substitution; Antibodies, Monoclonal; Antibody Specificity; Arginine; Aryl Hydrocarbon Hydroxylases; Cysteine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diclofenac; Enzyme-Linked Immunosorbent Assay; Genetic Variation; Humans; Hybridomas; Isoenzymes; Phenanthrenes; Polymorphism, Genetic; Protein Binding; Recombinant Proteins; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Tolbutamide | 2000 |
Desensitization of sulphonylurea- and nutrient-induced insulin secretion following prolonged treatment with glibenclamide.
Topics: Adenosine Triphosphate; Alanine; Animals; Arginine; Cell Line; Culture Media; Dose-Response Relationship, Drug; Glucose; Glyburide; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Potassium Channels; Potassium Chloride; Sulfonylurea Compounds; Tolbutamide | 2000 |
Glucose- and arginine-induced insulin secretion by human pancreatic beta-cells: the role of HERG K(+) channels in firing and release.
Topics: Arginine; ATP-Binding Cassette Transporters; Benzimidazoles; Cation Transport Proteins; DNA-Binding Proteins; Electric Conductivity; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Glucose; Humans; Insulin; Insulin Secretion; Islets of Langerhans; KATP Channels; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Potassium Channels, Voltage-Gated; Radioimmunoassay; Reproducibility of Results; Sulfanilamides; Tolbutamide; Trans-Activators; Transcriptional Regulator ERG | 2000 |
Neonatal treatment with beta-cell stimulatory agents reduces the incidence of diabetes in BB rats.
Topics: Animals; Animals, Newborn; Arginine; Diabetes Mellitus, Type 1; Drug Combinations; Female; Glucagon; Glucose; Incidence; Islets of Langerhans; Male; Protamines; Rats; Rats, Inbred BB; Theophylline; Time Factors; Tolbutamide | 2000 |
Transient neonatal diabetes mellitus, type 4, type 1 diabetes mellitus, or MODY: which disease is it, anyway?
Topics: Adult; Arginine; C-Peptide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Glucose Tolerance Test; Humans; Infant; Insulin; Insulin Secretion; Islets of Langerhans; Male; Tolbutamide | 2002 |
The molecular site of action of K(ATP) channel inhibitors determines their ability to inhibit iNOS-mediated relaxation in rat aorta.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Aminopyridines; Analysis of Variance; Animals; Aorta; Arginine; Barium; Endothelium, Vascular; Glyburide; Guanidines; Lipopolysaccharides; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Tolbutamide; Vasodilator Agents | 2002 |
Tungstate stimulates insulin release and inhibits somatostatin output in the perfused rat pancreas.
Topics: Animals; Arginine; Cysteamine; Exenatide; Glucose; Hypoglycemic Agents; In Vitro Techniques; Insulin; Insulin Secretion; Male; Pancreas; Peptides; Perfusion; Rats; Rats, Wistar; Somatostatin; Tolbutamide; Tungsten Compounds; Venoms | 2005 |
Dual mechanism of the potentiation by glucose of insulin secretion induced by arginine and tolbutamide in mouse islets.
Topics: Animals; Arginine; Calcium; Cytosol; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Glucose; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Tolbutamide | 2006 |
Detrimental actions of metabolic syndrome risk factor, homocysteine, on pancreatic beta-cell glucose metabolism and insulin secretion.
Topics: Alanine; Arginine; Calcium; Carbachol; Clone Cells; Colforsin; Culture Media; Dose-Response Relationship, Drug; Gastrointestinal Hormones; Glucose; Homocysteine; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Insulin-Secreting Cells; Keto Acids; Metabolic Syndrome; Potassium Chloride; Tetradecanoylphorbol Acetate; Tolbutamide | 2006 |
Peripheral antinociceptive effect of pertussis toxin: activation of the arginine/NO/cGMP/PKG/ ATP-sensitive K channel pathway.
Topics: Adenosine Triphosphate; Analgesia; Analgesics; Animals; Arginine; Bucladesine; Carbazoles; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dinoprostone; Enzyme Inhibitors; Ganglia, Spinal; Glyburide; Indoles; KATP Channels; Male; Neurons; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Pain; Pain Measurement; Pertussis Toxin; Potassium Channels, Inwardly Rectifying; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Tolbutamide | 2006 |
Pancreatic function of spontaneously diabetic torii rats in pre-diabetic stage.
Topics: Animals; Arginine; Benzoates; Body Weight; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucose Tolerance Test; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Male; Obesity; Organ Culture Techniques; Pancreas; Peptide Fragments; Rats; Rats, Sprague-Dawley; Tolbutamide | 2009 |
Glucagonotropic and Glucagonostatic Effects of KATP Channel Closure and Potassium Depolarization.
Topics: Animals; Arginine; Calcium; Cell Membrane; Female; Gliclazide; Glucagon; Glucagon-Secreting Cells; Glucose; Hypoglycemic Agents; Insulin; Insulin Secretion; Insulin-Secreting Cells; KATP Channels; Membrane Potentials; Mice; Potassium; Potassium Chloride; Tolbutamide | 2021 |
[Action of alkaloids from podophyllin on the response of pancreatic beta-cells of the rabbit to tolbutamide].
Topics: Animals; Etoposide; Insulin; Insulin Secretion; Islets of Langerhans; Podophyllotoxin; Rabbits; Teniposide; Tolbutamide | 1983 |