tolbutamide has been researched along with 4-aminopyridine in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (9.52) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 16 (76.19) | 29.6817 |
| 2010's | 2 (9.52) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Cho, YS; Hwang, EM; Jung, SY; Lim, SM; Min, SJ; Pae, AN; Park, KD; Viswanath, AN | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Castle, NA; Haylett, DG | 1 |
| Krnjevic, K; Leblond, J | 1 |
| Cahill, AL; Perlman, RL | 1 |
| Hescheler, J; Lenka, N; Su, J; Ullrich, S; Yu, H | 1 |
| Duarte, ID; Soares, AC | 1 |
| Bisaccia, F; Gasbarro, AR; Lograno, MD; Ostuni, A; Tamburro, AM | 1 |
| Castañeda-Hernández, G; Granados-Soto, V; Ortiz, MI; Rosas, R; Torres-López, JE; Vidal-Cantú, GC | 1 |
| Bernardi, G; Federici, M; Mercuri, NB; Natoli, S | 1 |
| Clapp, LH; Wilson, AJ | 1 |
| Argüelles, CF; Granados-Soto, V; Ortiz, MI | 1 |
| Castañeda-Hernández, G; Granados-Soto, V; Ortiz, MI | 2 |
| Ishikawa, T; Kaneko, Y; Nakayama, K; Sugino, F | 1 |
| Alves, DP; Amarante, LH; Duarte, ID | 1 |
| Bancila, V; Bloc, A; Dunant, Y; Nikonenko, I | 1 |
| Gerlach, U; Heitzmann, D; Lang, F; Ranta, F; Ris, F; Rösler, M; Su, J; Ullrich, S; Warth, R; Wittekindt, OH | 1 |
| Castañeda-Hernández, G; Castro-Olguín, J; Ortiz, MI; Peña-Samaniego, N | 1 |
| Granados-Soto, V; Medina-Tato, DA; Ortiz, MI; Palma-Martínez, J; Sarmiento-Heredia, D | 1 |
21 other study(ies) available for tolbutamide and 4-aminopyridine
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Identification of the first in silico-designed TREK1 antagonists that block channel currents dose dependently.
Topics: Animals; Computer Simulation; Crystallography, X-Ray; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Mice; Mice, Knockout; Molecular Docking Simulation; Potassium Channels, Tandem Pore Domain | 2016 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Effect of channel blockers on potassium efflux from metabolically exhausted frog skeletal muscle.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Apamin; Barium; Cell Membrane Permeability; Decamethonium Compounds; Dose-Response Relationship, Drug; Electric Stimulation; Glyburide; In Vitro Techniques; Ion Channels; Muscles; Potassium; Quinine; Rana temporaria; Rubidium; Scorpion Venoms; Tetraethylammonium Compounds; Tolbutamide | 1987 |
Hypoxic changes in hippocampal neurons.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Aminopyridines; Animals; Apamin; Caffeine; Calcium; Egtazic Acid; Electric Stimulation; Hippocampus; Hypoxia; Membrane Potentials; Neuroglia; Neuromuscular Depolarizing Agents; Neurons; Nitrogen; Quinine; Rats; Rats, Inbred Strains; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors; Tolbutamide | 1989 |
Tetraethylammonium selectively stimulates secretion from noradrenergic bovine chromaffin cells.
Topics: 4-Aminopyridine; Animals; Calcium; Catecholamines; Cattle; Cells, Cultured; Chromaffin System; Drug Interactions; Drug Synergism; Epinephrine; Glyburide; Nifedipine; Norepinephrine; Ouabain; Phorbol 12,13-Dibutyrate; Potassium Channel Blockers; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Tolbutamide | 1994 |
The expression and regulation of depolarization-activated K+ channels in the insulin-secreting cell line INS-1.
Topics: 1-Methyl-3-isobutylxanthine; 4-Aminopyridine; 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Animals; Calcium; Colforsin; Electric Conductivity; Gene Expression Regulation; Insulin; Insulin Secretion; Insulinoma; Pancreatic Neoplasms; Potassium Channel Blockers; Potassium Channels; Quaternary Ammonium Compounds; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetraethylammonium; Tolbutamide; Tumor Cells, Cultured | 2001 |
Dibutyryl-cyclic GMP induces peripheral antinociception via activation of ATP-sensitive K(+) channels in the rat PGE2-induced hyperalgesic paw.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Analgesics; Animals; Apamin; Cesium; Charybdotoxin; Dibutyryl Cyclic GMP; Dinoprostone; Dose-Response Relationship, Drug; Glyburide; Hindlimb; Hyperalgesia; Male; Pain; Pain Measurement; Pain Threshold; Potassium Channels; Rats; Rats, Wistar; Tetraethylammonium; Tolbutamide | 2001 |
Novel properties of peptides derived from the sequence coded by exon 26A of human elastin.
Topics: 4-Aminopyridine; Animals; Aorta; Dose-Response Relationship, Drug; Elastin; Enzyme Inhibitors; Exons; Glyburide; Humans; Hypoglycemic Agents; In Vitro Techniques; Lactose; Male; Models, Biological; Muscle, Smooth, Vascular; Nitroarginine; Peptides; Phenylephrine; Potassium Channel Blockers; Rats; Rats, Wistar; Tolbutamide; Vasoconstrictor Agents; Virulence Factors, Bordetella | 2002 |
Pharmacological evidence for the activation of K(+) channels by diclofenac.
Topics: 4-Aminopyridine; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apamin; Behavior, Animal; Charybdotoxin; Diclofenac; Dose-Response Relationship, Drug; Female; Formaldehyde; Glyburide; Hindlimb; Morphine; Pain; Pinacidil; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Tetraethylammonium; Tolbutamide | 2002 |
Dopamine selectively reduces GABA(B) transmission onto dopaminergic neurones by an unconventional presynaptic action.
Topics: 4-Aminopyridine; Animals; Dopamine; Dopamine Agents; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; gamma-Aminobutyric Acid; Hypoglycemic Agents; Levodopa; Male; Membrane Potentials; Neural Inhibition; Neurons; Organ Culture Techniques; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, GABA-B; Receptors, Presynaptic; Serotonin; Synaptic Transmission; Tolbutamide | 2002 |
The molecular site of action of K(ATP) channel inhibitors determines their ability to inhibit iNOS-mediated relaxation in rat aorta.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Aminopyridines; Analysis of Variance; Animals; Aorta; Arginine; Barium; Endothelium, Vascular; Glyburide; Guanidines; Lipopolysaccharides; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Tolbutamide; Vasodilator Agents | 2002 |
The peripheral antinociceptive effect of resveratrol is associated with activation of potassium channels.
Topics: 4-Aminopyridine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apamin; ATP-Binding Cassette Transporters; Charybdotoxin; Female; Glipizide; Glyburide; KATP Channels; Morphine; Narcotics; Peripheral Nervous System; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Potassium Channels, Inwardly Rectifying; Rats; Rats, Wistar; Resveratrol; Stilbenes; Tetraethylammonium; Tolbutamide | 2002 |
Possible involvement of potassium channels in peripheral antinociception induced by metamizol: lack of participation of ATP-sensitive K+ channels.
Topics: 4-Aminopyridine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apamin; Area Under Curve; ATP-Binding Cassette Transporters; Charybdotoxin; Dipyrone; Drug Interactions; Female; Formaldehyde; Glyburide; KATP Channels; Pain Measurement; Peripheral Nerves; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Rats, Wistar; Tetraethylammonium; Tolbutamide | 2003 |
Two distinct effects of cGMP on cytosolic Ca2+ concentration of rat pancreatic beta-cells.
Topics: 4-Aminopyridine; Animals; Calcium; Cyclic GMP; Cytosol; Dimethyl Sulfoxide; Enzyme Inhibitors; Glucose; Hydrazines; Hypoglycemic Agents; Islets of Langerhans; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Potassium; Potassium Channel Blockers; Quinoxalines; Rats; Tolbutamide | 2003 |
Study of the involvement of K+ channels in the peripheral antinociception of the kappa-opioid receptor agonist bremazocine.
Topics: 4-Aminopyridine; Analgesics; Animals; ATP-Binding Cassette Transporters; Benzomorphans; Charybdotoxin; Cyclic GMP; Dequalinium; Glyburide; Hyperalgesia; KATP Channels; Male; Naltrexone; Nitric Oxide; Peripheral Nervous System; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Rats, Wistar; Receptors, Opioid, kappa; Signal Transduction; Tetraethylammonium; Tolbutamide | 2004 |
Zinc inhibits glutamate release via activation of pre-synaptic K channels and reduces ischaemic damage in rat hippocampus.
Topics: 4-Aminopyridine; Animals; Animals, Newborn; Brain Ischemia; Chelating Agents; Chlorocebus aethiops; COS Cells; Drug Interactions; Edetic Acid; Glutamic Acid; Gramicidin; Hippocampus; Ionophores; Luminescent Measurements; Male; Membrane Proteins; Microscopy, Electron; Mossy Fibers, Hippocampal; Organ Culture Techniques; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Potassium Chloride; Presynaptic Terminals; Rats; Rats, Wistar; Synaptosomes; Time Factors; Tolbutamide; Transfection; Valinomycin; Zinc | 2004 |
Pharmacological evidence for the activation of Ca2+-activated K+ channels by meloxicam in the formalin test.
Topics: 4-Aminopyridine; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Apamin; Behavior, Animal; Charybdotoxin; Dose-Response Relationship, Drug; Female; Formaldehyde; Glyburide; Meloxicam; Pain; Pain Measurement; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Potassium Channels, Inwardly Rectifying; Rats; Rats, Wistar; Tetraethylammonium; Thiazines; Thiazoles; Tolbutamide | 2005 |
Effects of I(Ks) channel inhibitors in insulin-secreting INS-1 cells.
Topics: 4-Aminopyridine; Animals; Cell Line, Tumor; Chromans; Gene Expression; Insulin; Insulin Secretion; Insulin-Secreting Cells; KCNQ1 Potassium Channel; Membrane Potentials; Rats; Sulfonamides; Tetraethylammonium; Tolbutamide | 2005 |
Probable activation of the opioid receptor-nitric oxide-cyclic GMP-K+ channels pathway by codeine.
Topics: 4-Aminopyridine; Analgesics, Opioid; Animals; Codeine; Cyclic GMP; Female; Glyburide; Methylene Blue; Naloxone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium Channels; Rats; Rats, Wistar; Receptors, Opioid; Tetraethylammonium; Tolbutamide | 2005 |
Possible activation of the NO-cyclic GMP-protein kinase G-K+ channels pathway by gabapentin on the formalin test.
Topics: 4-Aminopyridine; Amines; Analgesics; Animals; Apamin; Carbazoles; Charybdotoxin; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Glyburide; Indoles; Naloxone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain Measurement; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Tolbutamide | 2006 |