tocotrienol--delta and 4-hydroxyphenylmethylene-hydantoin

tocotrienol--delta has been researched along with 4-hydroxyphenylmethylene-hydantoin* in 1 studies

Other Studies

1 other study(ies) available for tocotrienol--delta and 4-hydroxyphenylmethylene-hydantoin

Article	Year
Synthesis of fluorescent analogues of the anticancer natural products 4-hydroxyphenylmethylene hydantoin and delta-tocotrienol. Natural product communications, 2010, Volume: 5, Issue:10 4-Hydroxyphenylmethylene hydantoin (PMH, 1), isolated from the Red Sea sponge Hemimycale arabica, and delta-tocotrienol (3), isolated from the tocotrienol-rich fraction of palm oil, are important antimetastatic and antiproliferative natural products that proved effective against metastatic prostate and breast cancers, respectively. New fluorescent derivatives of PMH (2) and delta-tocotrienol (4) were synthesized by Steglich esterification. Both 2 and 4 retained good anti-migratory and antiproliferative activities, respectively. Fluorescent analogues 2 and 4 can be used for the identification of molecular targets of 1 and 3 in tumor cell cultures. Topics: Animals; Benzylidene Compounds; Fluorescent Dyes; Hydantoins; Palm Oil; Plant Oils; Porifera; Vitamin E	2010

Article

Year

Synthesis of fluorescent analogues of the anticancer natural products 4-hydroxyphenylmethylene hydantoin and delta-tocotrienol.

Natural product communications, 2010, Volume: 5, Issue:10

4-Hydroxyphenylmethylene hydantoin (PMH, 1), isolated from the Red Sea sponge Hemimycale arabica, and delta-tocotrienol (3), isolated from the tocotrienol-rich fraction of palm oil, are important antimetastatic and antiproliferative natural products that proved effective against metastatic prostate and breast cancers, respectively. New fluorescent derivatives of PMH (2) and delta-tocotrienol (4) were synthesized by Steglich esterification. Both 2 and 4 retained good anti-migratory and antiproliferative activities, respectively. Fluorescent analogues 2 and 4 can be used for the identification of molecular targets of 1 and 3 in tumor cell cultures.

Topics: Animals; Benzylidene Compounds; Fluorescent Dyes; Hydantoins; Palm Oil; Plant Oils; Porifera; Vitamin E

2010