tocotrienol--alpha has been researched along with quinone* in 1 studies
1 other study(ies) available for tocotrienol--alpha and quinone
| Article | Year |
|---|---|
α-Tocotrienol quinone modulates oxidative stress response and the biochemistry of aging.
We report that α-tocotrienol quinone (ATQ3) is a metabolite of α-tocotrienol, and that ATQ3 is a potent cellular protectant against oxidative stress and aging. ATQ3 is orally bioavailable, crosses the blood-brain barrier, and has demonstrated clinical response in inherited mitochondrial disease in open label studies. ATQ3 activity is dependent upon reversible 2e-redox-cycling. ATQ3 may represent a broader class of unappreciated dietary-derived phytomolecular redox motifs that digitally encode biochemical data using redox state as a means to sense and transfer information essential for cellular function. Topics: Aging; Animals; Antioxidants; Benzoquinones; Cells, Cultured; Dogs; Dose-Response Relationship, Drug; Humans; Mice; Molecular Structure; Oxidative Stress; Rats; Tocotrienols; Vitamin E | 2011 |