tocophersolan has been researched along with paclitaxel in 60 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (1.67) | 18.2507 |
2000's | 10 (16.67) | 29.6817 |
2010's | 39 (65.00) | 24.3611 |
2020's | 10 (16.67) | 2.80 |
Authors | Studies |
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Dintaman, JM; Silverman, JA | 1 |
Feng, SS; Mu, L | 3 |
Feng, SS; Zhang, Z | 2 |
Feng, SS; Win, KY | 1 |
Mu, L; Seow, PH | 1 |
Dong, Y; Feng, SS; Zhang, Z | 1 |
Feng, SS; Pan, J | 1 |
Chang, YW; Chao, YS; Chen, CT; Chiang, TH; Ho, PY; Lin, HL; Lo, YK; Wu, HY; Wu, SH; Yao, HT; Yeh, TK | 1 |
Feng, SS; Zhao, L | 1 |
Liu, W; Nie, N; Song, N; Tu, Q; Wang, J; Zhang, Y | 1 |
Chandran, T; Katragadda, U; Rayaprolu, BM; Tan, C; Teng, Q | 1 |
Cao, W; He, ZG; Lian, H; Liu, YH; Sun, J; Sun, YH; Wang, SL; Wang, YJ; Yu, YP | 1 |
Gill, KK; Kaddoumi, A; Nazzal, S | 1 |
Chen, L; Li, Y; Shen, J; Yin, Q; Zhang, Z | 1 |
Li, Y; Shen, J; Sun, H; Wang, S; Xu, P; Yin, Q; Yu, H; Zhang, Z | 1 |
Huang, B; Liu, CS; Wang, G; Wu, Y; Yu, B; Yuan, Y | 1 |
Fu, Q; Liu, F; Racette, K; Ramishetti, S; Tang, J; Wang, D; Wang, Y | 1 |
Chen, H; Dong, Y; Huang, H; Zhang, J; Zhang, W; Zhao, T; Zhu, J | 1 |
Gao, L; Kang, J; Liu, G; Ma, J; Niu, M; Wang, H; Wang, X; Wang, Z | 1 |
Bernabeu, E; Chiappetta, DA; Gonzalez, L; Helguera, G; Hocht, C; Legaspi, MJ; Taira, C | 1 |
Li, Y; Meng, Q; Shen, J; Sui, H; Yin, Q; Yu, H; Zhang, Z | 1 |
Fallon, JK; Fu, Q; He, Z; Liu, D; Liu, F; Ma, Y; Wang, D; Wang, Y; Yang, X | 1 |
Bu, H; He, X; Li, Y; Yin, Q; Yu, H; Zhang, Z | 1 |
Kulhari, H; Mukherjee, S; Pooja, D; Rachamalla, SS; Singh, MK; Sistla, R | 1 |
Cui, Y; Li, L; Li, Y; Zhao, Y | 1 |
Bao, Y; Cheng, B; Guo, Y; Li, D; Tan, S; Zhang, Z; Zhuang, X | 1 |
Chen, Y; Lee, RJ; Sun, Y; Tang, S; Teng, L; Wang, G; Wu, Y; Xu, S; Yu, B; Yuan, Y; Zhang, X | 1 |
Bao, Y; Chu, Q; Tan, S; Wu, T; Wu, Y; Zhang, Z; Zhuang, X | 1 |
Assanhou, AG; Kong, L; Li, W; Mo, R; Sun, H; Xue, L; Zhang, C; Zhang, L | 1 |
Bernabeu, E; Cagel, M; Chiappetta, DA; Gergic, EP; Gonzalez, L; Moretton, MA | 1 |
Bikiaris, DN; Filippousi, M; Leus, K; Nanaki, SG; Siafaka, PI; Tseligka, ED; Turner, S; Van Der Voort, P; Van Tendeloo, G; Vandichel, M; Vizirianakis, IS | 1 |
Fallon, JK; Liu, D; Liu, F; Liu, H; Ma, Y | 1 |
Bernabeu, E; Chiappetta, DA; Gonzalez, L; Legaspi, MJ; Moretton, MA | 1 |
He, W; Luan, Y; Yang, S; Zhang, H; Zhao, D | 1 |
Jin, X; Li, M; Lv, H; Yin, L; Zhang, Z; Zhou, J | 1 |
Jia, X; Song, J; Yan, H; Zhang, Z | 1 |
Chen, Y; Feng, S; Gao, F; Liu, W; Yin, P; Yuan, Z | 1 |
Abu-Fayyad, A; Cardelli, J; Carroll, JL; Cody, R; Dragoi, AM; Kamal, MM; Nazzal, S | 1 |
Fu, S; Han, L; Lin, J; Liu, C; Lu, X; Yang, C; Zhao, C | 1 |
Baek, JS; Cho, CW; Han, SM; Hwang, SJ; Kim, MS | 1 |
Choudhury, H; Gorain, B; Kesharwani, P; Pandey, M | 1 |
Bhatta, RS; Chandasana, H; Chourasia, MK; Dixit, S; Kesharwani, P; Konwar, R; Meher, JG; Pathan, DK; Pawar, VK; Sharma, M; Singh, Y | 1 |
Ding, H; Ge, Y; Li, L; Yang, M; Zhu, Y | 1 |
Chen, Y; Chen, ZS; Gao, W; Jiang, Y; Lin, Z; Wang, B; Wu, S; Yang, X | 1 |
Li, W; Xu, H; Xue, J | 1 |
Du, X; Feng, H; Lei, M; Ma, G; Sha, S; Wang, X; Zhu, Y | 1 |
Lee, BJ; Ngo, HV; Tran, PHL; Tran, TTD | 1 |
Ding, Y; Gao, M; Li, L; Ma, C; Ma, X; Wang, C; Wang, Y; Xu, Y | 1 |
Chourasia, MK; Dixit, S; Konwar, R; Meher, JG; Pawar, VK; Saklani, R; Singh, Y | 1 |
Chen, R; Kuang, X; Tang, R; Wang, X; Wang, Z; Wu, S; Yan, G | 1 |
Fang, K; Gao, X; Guo, D; Hu, S; Ji, C; Ji, H; Jiang, S; Li, G; Peng, L; Si, H; Song, X; Wang, J; Zhang, J; Zuo, R | 1 |
Gong, Y; Li, Y; Li, Z; Wu, T; Xiong, X | 1 |
Bi, D; Feng, L; Fu, J; Guo, Y; Han, J; Han, M; Wang, X; Zou, Y | 1 |
Li, J; Luo, K; Wang, G; Xu, F; Yao, T; Yu, H; Zhu, J | 1 |
Chen, J; Ding, W; Feng, J; Li, F; Li, Y; Liang, D; Tang, L; Xie, T; Yang, X; Zhang, Z; Zou, L | 1 |
Dora, CP; Ghadi, R; Jain, S; Katiyar, SS; Kuche, K; Kushwah, V; Patil, R | 1 |
Chauhan, D; Chourasia, MK; Gayen, JR; Kalleti, N; Kedar, AS; Mishra, K; Mitra, K; Mugale, MN; Rana, R; Rath, SK; Saklani, R; Sharma, D; Tiwari, AK; Verma, S; Wahajuddin, M; Yadav, P; Yadav, PK | 1 |
1 review(s) available for tocophersolan and paclitaxel
Article | Year |
---|---|
Paclitaxel loaded vitamin E-TPGS nanoparticles for cancer therapy.
Topics: Animals; Drug Delivery Systems; Humans; Nanoparticles; Nanotechnology; Neoplasms; Paclitaxel; Vitamin E | 2018 |
59 other study(ies) available for tocophersolan and paclitaxel
Article | Year |
---|---|
Inhibition of P-glycoprotein by D-alpha-tocopheryl polyethylene glycol 1000 succinate (TPGS).
Topics: 3T3 Cells; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Survival; Coloring Agents; Cyclosporine; Fluorouracil; Immunosuppressive Agents; Mice; Micelles; Paclitaxel; Polyethylene Glycols; Rhodamine 123; Vinblastine; Vitamin E | 1999 |
Vitamin E TPGS used as emulsifier in the solvent evaporation/extraction technique for fabrication of polymeric nanospheres for controlled release of paclitaxel (Taxol).
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Delayed-Action Preparations; Excipients; Microspheres; Nanotechnology; Paclitaxel; Polyethylene Glycols; Polymers; Solvents; Vitamin E | 2002 |
A novel controlled release formulation for the anticancer drug paclitaxel (Taxol): PLGA nanoparticles containing vitamin E TPGS.
Topics: Antineoplastic Agents, Phytogenic; Chemistry, Pharmaceutical; Delayed-Action Preparations; Lactic Acid; Nanotechnology; Paclitaxel; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Vitamin E | 2003 |
PLGA/TPGS nanoparticles for controlled release of paclitaxel: effects of the emulsifier and drug loading ratio.
Topics: Delayed-Action Preparations; Drug Compounding; Emulsifying Agents; Lactic Acid; Nanotechnology; Paclitaxel; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Vitamin E | 2003 |
Nanoparticles of poly(lactide)/vitamin E TPGS copolymer for cancer chemotherapy: synthesis, formulation, characterization and in vitro drug release.
Topics: Antineoplastic Agents, Phytogenic; Drug Carriers; Drug Therapy; Humans; Lactic Acid; Molecular Structure; Molecular Weight; Nanostructures; Neoplasms; Paclitaxel; Particle Size; Polyesters; Polyethylene Glycols; Polymers; Surface Properties; Vitamin E | 2006 |
In vitro and in vivo studies on vitamin E TPGS-emulsified poly(D,L-lactic-co-glycolic acid) nanoparticles for paclitaxel formulation.
Topics: Antineoplastic Agents, Phytogenic; Area Under Curve; Drug Carriers; Drug Delivery Systems; Emulsifying Agents; Glycerol; Humans; Lactic Acid; Nanostructures; Paclitaxel; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Surface-Active Agents; Vitamin E | 2006 |
Application of TPGS in polymeric nanoparticulate drug delivery system.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Antineoplastic Agents, Phytogenic; Cell Membrane; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Kinetics; Nanotechnology; Paclitaxel; Polyethylene Glycols; Polymers; Surface Properties; Vitamin E | 2006 |
Self-assembled nanoparticles of poly(lactide)--Vitamin E TPGS copolymers for oral chemotherapy.
Topics: Administration, Oral; Antineoplastic Agents, Phytogenic; Caco-2 Cells; Calorimetry, Differential Scanning; Cell Survival; Chemistry, Pharmaceutical; Humans; Hydrogen-Ion Concentration; Nanoparticles; Paclitaxel; Particle Size; Polyesters; Polyethylene Glycols; Solubility; Vitamin E | 2006 |
d-alpha-Tocopheryl polyethylene glycol 1000 succinate (TPGS) modified poly(l-lactide) (PLLA) films for localized delivery of paclitaxel.
Topics: Calorimetry, Differential Scanning; Drug Delivery Systems; Paclitaxel; Polyesters; Polyethylene Glycols; Solubility; Tensile Strength; Vitamin E | 2008 |
Targeted delivery of paclitaxel using folate-decorated poly(lactide)-vitamin E TPGS nanoparticles.
Topics: Antineoplastic Agents, Phytogenic; Brain Neoplasms; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Drug Delivery Systems; Female; Folic Acid; Humans; Molecular Structure; Nanoparticles; Nanotechnology; Paclitaxel; Particle Size; Polyesters; Polyethylene Glycols; Spectrum Analysis; Vitamin E | 2008 |
Enhanced oral bioavailability of paclitaxel by D-alpha-tocopheryl polyethylene glycol 400 succinate in mice.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Biological Availability; Caco-2 Cells; Ethanol; Glycerol; Humans; Injections, Intravenous; Male; Mice; Mice, Inbred BALB C; Microsomes, Liver; Paclitaxel; Permeability; Polyethylene Glycols; Rhodamine 123; Solvents; Steroid Hydroxylases; Vitamin E | 2008 |
Enhanced oral bioavailability of paclitaxel formulated in vitamin E-TPGS emulsified nanoparticles of biodegradable polymers: in vitro and in vivo studies.
Topics: Absorbable Implants; Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Biological Availability; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Carriers; Electrochemistry; Excipients; Humans; Lactic Acid; Light; Microscopy, Electron, Scanning; Nanoparticles; Paclitaxel; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Sprague-Dawley; Scattering, Radiation; Vitamin E | 2010 |
Folate-decorated hybrid polymeric nanoparticles for chemically and physically combined paclitaxel loading and targeted delivery.
Topics: Animals; Antineoplastic Agents, Phytogenic; Drug Delivery Systems; Drug Screening Assays, Antitumor; Folic Acid; HeLa Cells; Humans; Mice; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Nanoparticles; NIH 3T3 Cells; Paclitaxel; Particle Size; Polyesters; Polyethylene Glycols; Vitamin E | 2011 |
Multi-drug delivery to tumor cells via micellar nanocarriers.
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzoquinones; Cell Line, Tumor; Cell Proliferation; Delayed-Action Preparations; Drug Carriers; Drug Combinations; Drug Delivery Systems; Female; Half-Life; Humans; Lactams, Macrocyclic; Micelles; Nanoparticles; Ovarian Neoplasms; Paclitaxel; Phosphatidylethanolamines; Polyethylene Glycols; Vitamin E | 2011 |
Supramolecular micellar nanoaggregates based on a novel chitosan/vitamin E succinate copolymer for paclitaxel selective delivery.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Chitosan; Delayed-Action Preparations; Diffusion; Female; Humans; Micelles; Nanocapsules; Paclitaxel; Polyethylene Glycols; Vitamin E | 2011 |
Mixed micelles of PEG(2000)-DSPE and vitamin-E TPGS for concurrent delivery of paclitaxel and parthenolide: enhanced chemosenstization and antitumor efficacy against non-small cell lung cancer (NSCLC) cell lines.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Drug Carriers; Humans; Inhibitory Concentration 50; Lung Neoplasms; Magnetic Resonance Spectroscopy; Micelles; Paclitaxel; Particle Size; Phosphatidylethanolamines; Polyethylene Glycols; Sesquiterpenes; Vitamin E | 2012 |
Co-delivery of paclitaxel and survivin shRNA by pluronic P85-PEI/TPGS complex nanoparticles to overcome drug resistance in lung cancer.
Topics: Animals; Apoptosis; Cell Cycle; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; Imines; Inhibitor of Apoptosis Proteins; Lung Neoplasms; Male; Mice; Mice, Nude; Paclitaxel; Poloxalene; Polyethylene Glycols; Polyethylenes; RNA, Small Interfering; Survivin; Vitamin E | 2012 |
Simultaneous inhibition of metastasis and growth of breast cancer by co-delivery of twist shRNA and paclitaxel using pluronic P85-PEI/TPGS complex nanoparticles.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Carcinoma; Drug Combinations; Female; Genetic Therapy; Imines; Mice; Mice, Inbred BALB C; Mice, Nude; Nanocapsules; Paclitaxel; Poloxalene; Polyethylene Glycols; Polyethylenes; RNA, Small Interfering; Transfection; Treatment Outcome; Vitamin E | 2013 |
Controlled preparation and antitumor efficacy of vitamin E TPGS-functionalized PLGA nanoparticles for delivery of paclitaxel.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chemical Precipitation; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Female; Humans; Lactic Acid; Lung Neoplasms; Mice; Mice, Nude; Microscopy, Electron, Transmission; Nanoparticles; Paclitaxel; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Treatment Outcome; Tumor Burden; Vitamin E; Xenograft Model Antitumor Assays | 2013 |
Multifunctional nanoparticles based on a single-molecule modification for the treatment of drug-resistant cancer.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Drug Design; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluorouracil; Humans; Hydrolysis; Models, Chemical; Nanoparticles; Neoplasms; Paclitaxel; Polyethylene Glycols; Rhodamine 123; Vitamin E | 2013 |
Paclitaxel-loaded poly(glycolide-co-ε-caprolactone)-b-D-α-tocopheryl polyethylene glycol 2000 succinate nanoparticles for lung cancer therapy.
Topics: Animals; Antineoplastic Agents; Body Weight; Cell Line, Tumor; Cell Survival; Coumarins; Drug Delivery Systems; Humans; Lung Neoplasms; Mice; Mice, Nude; Nanoparticles; Neoplasms, Experimental; Paclitaxel; Polyesters; Polyethylene Glycols; Thiazoles; Vitamin E; Xenograft Model Antitumor Assays | 2013 |
Paclitaxel nanosuspensions coated with P-gp inhibitory surfactants: I. Acute toxicity and pharmacokinetics studies.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Coated Materials, Biocompatible; Mice; Nanoparticles; Paclitaxel; Particle Size; Polyethylene Glycols; Surface-Active Agents; Suspensions; Toxicity Tests, Acute; Vitamin E | 2013 |
Paclitaxel-loaded PCL-TPGS nanoparticles: in vitro and in vivo performance compared with Abraxane®.
Topics: Albumin-Bound Paclitaxel; Albumins; Animals; Calorimetry, Differential Scanning; Cell Line, Tumor; Cell Proliferation; Humans; Male; Nanoparticles; Paclitaxel; Polyesters; Polyethylene Glycols; Polymers; Rats; Rats, Wistar; Vitamin E | 2014 |
iRGD conjugated TPGS mediates codelivery of paclitaxel and survivin shRNA for the reversal of lung cancer resistance.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Drug Delivery Systems; Drug Resistance, Neoplasm; Humans; Inhibitor of Apoptosis Proteins; Integrin alphaVbeta3; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Nanotechnology; Oligopeptides; Paclitaxel; Permeability; Polyethylene Glycols; RNA Interference; RNA, Small Interfering; Survivin; Vitamin E | 2014 |
Combinational delivery of hydrophobic and hydrophilic anticancer drugs in single nanoemulsions to treat MDR in cancer.
Topics: Adenosine Triphosphatases; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Cell Line, Tumor; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Emulsions; Female; Fluorouracil; Humans; Hydrophobic and Hydrophilic Interactions; Inhibitory Concentration 50; Mice; Mice, Nude; Nanomedicine; Neoplasm Transplantation; Paclitaxel; Polyethylene Glycols; Skin Neoplasms; Vitamin E | 2014 |
A TPGS-incorporating nanoemulsion of paclitaxel circumvents drug resistance in breast cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Cycle; Cell Survival; Drug Carriers; Drug Resistance, Neoplasm; Emulsions; Humans; Inhibitory Concentration 50; Mammary Neoplasms, Experimental; MCF-7 Cells; Membrane Potential, Mitochondrial; Mice, Nude; Nanostructures; Paclitaxel; Vitamin E; Xenograft Model Antitumor Assays | 2014 |
Dendrimer-TPGS mixed micelles for enhanced solubility and cellular toxicity of taxanes.
Topics: Animals; Cell Death; Cell Line; Cell Survival; Dendrimers; Docetaxel; Hemolysis; Humans; Hydrogen-Ion Concentration; Micelles; Paclitaxel; Particle Size; Polyethylene Glycols; Rats; Solubility; Spectroscopy, Fourier Transform Infrared; Static Electricity; Taxoids; Vitamin E; X-Ray Diffraction | 2014 |
Stable phosphatidylcholine-bile salt mixed micelles enhance oral absorption of paclitaxel: preparation and mechanism in rats.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; Cell Line, Tumor; Drug Carriers; Drug Stability; Glycine max; Humans; Intestinal Absorption; Male; Micelles; Paclitaxel; Permeability; Phosphatidylcholines; Poloxamer; Polyethylene Glycols; Polyethyleneimine; Rats; Rats, Wistar; Sodium Cholate; Vitamin E | 2014 |
D-α-tocopherol polyethylene glycol succinate-based redox-sensitive paclitaxel prodrug for overcoming multidrug resistance in cancer cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Carriers; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; G2 Phase Cell Cycle Checkpoints; Half-Life; Humans; Mice; Micelles; Ovarian Neoplasms; Oxidation-Reduction; Paclitaxel; Polyethylene Glycols; Prodrugs; Rats; Rats, Sprague-Dawley; Vitamin E | 2014 |
Enhanced antitumor efficacy of vitamin E TPGS-emulsified PLGA nanoparticles for delivery of paclitaxel.
Topics: Animals; Cell Line, Tumor; Ethanol; Female; Humans; Lactic Acid; Mice; Mice, Nude; Nanoparticles; Paclitaxel; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vitamin E; Water; Xenograft Model Antitumor Assays | 2014 |
D-α-tocopherol polyethylene glycol succinate-based derivative nanoparticles as a novel carrier for paclitaxel delivery.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Drug Delivery Systems; Female; Humans; Lung Neoplasms; MCF-7 Cells; Mice; Micelles; Nanoparticles; Ovarian Neoplasms; Paclitaxel; Particle Size; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Sarcoma; Succinates; Vitamin E | 2015 |
Reversal of multidrug resistance by co-delivery of paclitaxel and lonidamine using a TPGS and hyaluronic acid dual-functionalized liposome for cancer treatment.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Hyaluronic Acid; Indazoles; Lipids; Liposomes; Male; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Neoplasms; Paclitaxel; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Vitamin E | 2015 |
Novel Soluplus(®)-TPGS mixed micelles for encapsulation of paclitaxel with enhanced in vitro cytotoxicity on breast and ovarian cancer cell lines.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Drug Compounding; Drug Liberation; Female; Humans; Immunoblotting; MCF-7 Cells; Micelles; Microscopy, Electron, Transmission; Nanoparticles; Ovarian Neoplasms; Paclitaxel; Poly(ADP-ribose) Polymerases; Polyethylene Glycols; Polyvinyls; Solubility; Vitamin E | 2016 |
Biocompatible Zr-based nanoscale MOFs coated with modified poly(ε-caprolactone) as anticancer drug carriers.
Topics: Antineoplastic Agents; Caproates; Cell Line, Tumor; Cisplatin; Coated Materials, Biocompatible; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Humans; Hydrophobic and Hydrophilic Interactions; Lactones; Nanoparticles; Paclitaxel; Particle Size; Polyethylene Glycols; Polymers; Vitamin E; Zirconium | 2016 |
The Effect of Surfactant on Paclitaxel Nanocrystals: An In Vitro and In Vivo Study.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Size; Diffusion; Female; Metabolic Clearance Rate; Mice; Mice, Inbred C57BL; Nanocapsules; Neoplasms, Experimental; Organ Specificity; Paclitaxel; Polyethylene Glycols; Surface-Active Agents; Tissue Distribution; Treatment Outcome; Vitamin E | 2016 |
Paclitaxel-Loaded TPGS-b-PCL Nanoparticles: In Vitro Cytotoxicity and Cellular Uptake in MCF-7 and MDA-MB-231 Cells versus mPEG-b-PCL Nanoparticles and Abraxane®.
Topics: Albumin-Bound Paclitaxel; Cytotoxins; Female; Humans; MCF-7 Cells; Nanoparticles; Neoplasms; Paclitaxel; Polyesters; Polyethylene Glycols; Vitamin E | 2016 |
Redox-sensitive mPEG-SS-PTX/TPGS mixed micelles: An efficient drug delivery system for overcoming multidrug resistance.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Ethylene Glycols; Humans; MCF-7 Cells; Micelles; Oxidation-Reduction; Paclitaxel; Vitamin E | 2016 |
Tyroservatide-TPGS-paclitaxel liposomes: Tyroservatide as a targeting ligand for improving breast cancer treatment.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Cell Line, Tumor; Drug Combinations; Drug Delivery Systems; Female; Humans; Liposomes; Mice; Mice, Nude; Oligopeptides; Paclitaxel; Vitamin E | 2017 |
Hyaluronic acid-modified didecyldimethylammonium bromide/ d-a-tocopheryl polyethylene glycol succinate mixed micelles for delivery of baohuoside I against non-small cell lung cancer: in vitro and in vivo evaluation.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Flavonoids; Humans; Hyaluronic Acid; Inhibitory Concentration 50; Injections, Intravenous; Lung Neoplasms; Male; Mice, Inbred BALB C; Mice, Nude; Micelles; Paclitaxel; Quaternary Ammonium Compounds; Solubility; Surface Properties; Technology, Pharmaceutical; Time Factors; Vitamin E; Xenograft Model Antitumor Assays | 2017 |
Vitamin E Succinate-Grafted-Chitosan Oligosaccharide/RGD-Conjugated TPGS Mixed Micelles Loaded with Paclitaxel for U87MG Tumor Therapy.
Topics: alpha-Tocopherol; Animals; Antineoplastic Agents; Cell Line, Tumor; Chitosan; Drug Carriers; Glioma; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Micelles; Nanoparticles; Oligopeptides; Oligosaccharides; Paclitaxel; Particle Size; Succinates; Vitamin E | 2017 |
Development and in-vitro characterization of nanoemulsions loaded with paclitaxel/γ-tocotrienol lipid conjugates.
Topics: Antineoplastic Agents; Cell Line, Tumor; Chemistry, Pharmaceutical; Emulsions; Humans; Lipids; Nanoparticles; Paclitaxel; Polyethylene Glycols; Tocotrienols; Vitamin E | 2018 |
Redox-responsive F127-folate/F127-disulfide bond-d-α-tocopheryl polyethylene glycol 1000 succinate/P123 mixed micelles loaded with paclitaxel for the reversal of multidrug resistance in tumors.
Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; Disulfides; Drug Liberation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Endocytosis; Folic Acid; Humans; Inhibitory Concentration 50; MCF-7 Cells; Micelles; Mitochondria; Neoplasms; Oxidation-Reduction; Paclitaxel; Poloxalene; Poloxamer; Reactive Oxygen Species; Vitamin E | 2018 |
Surface modification of paclitaxel-loaded liposomes using d-α-tocopheryl polyethylene glycol 1000 succinate: Enhanced cellular uptake and cytotoxicity in multidrug resistant breast cancer cells.
Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Cell Survival; Drug Liberation; Drug Resistance, Neoplasm; Female; Humans; Liposomes; MCF-7 Cells; Microscopy, Confocal; Paclitaxel; Particle Size; Polysorbates; Solubility; Vitamin E | 2018 |
Paclitaxel-loaded TPGS enriched self-emulsifying carrier causes apoptosis by modulating survivin expression and inhibits tumour growth in syngeneic mammary tumours.
Topics: Animals; Apoptosis; Drug Delivery Systems; Emulsions; Female; Humans; Isografts; Mammary Neoplasms, Experimental; MCF-7 Cells; Micelles; Neoplasm Transplantation; Paclitaxel; Rats; Rats, Sprague-Dawley; Vitamin E | 2018 |
Co-delivery of paclitaxel and doxorubicin using mixed micelles based on the redox sensitive prodrugs.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Disulfides; Doxorubicin; Drug Delivery Systems; Drug Liberation; Female; Melanoma, Experimental; Mice; Micelles; Oxidation-Reduction; Paclitaxel; Prodrugs; Propionates; Tumor Burden; Vitamin E | 2019 |
A personalized and long-acting local therapeutic platform combining photothermal therapy and chemotherapy for the treatment of multidrug-resistant colon tumor.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Combined Modality Therapy; Drug Liberation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Elastic Modulus; Gold; Humans; Hydrogels; Hyperthermia, Induced; Inhibitory Concentration 50; Male; Mice, Nude; Micelles; Nanoparticles; Nanotubes; Neoplasm Recurrence, Local; Paclitaxel; Phototherapy; Polyethylene Glycols; Temperature; Time Factors; Vitamin E | 2018 |
Combined administration of PTX and S-HM-3 in TPGS/Solutol micelle system for oncotarget therapy.
Topics: Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Movement; Drug Carriers; Female; Humans; Inhibitory Concentration 50; Male; Mice, Inbred BALB C; Mice, Nude; Micelles; Neoplasms; Paclitaxel; Polyethylene Glycols; Stearic Acids; Tissue Distribution; Tumor Burden; Vitamin E; Whole Body Imaging | 2019 |
Dual-functionalized liposome by co-delivery of paclitaxel with sorafenib for synergistic antitumor efficacy and reversion of multidrug resistance.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Female; Humans; Hyaluronic Acid; Liposomes; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Paclitaxel; Polyethylene Glycols; Polymers; Rats; Sorafenib; Vitamin E | 2019 |
The roles of a surfactant in zein-HPMC blend solid dispersions for improving drug delivery.
Topics: Crystallization; Drug Liberation; Hydrophobic and Hydrophilic Interactions; Hypromellose Derivatives; Paclitaxel; Surface-Active Agents; Vitamin E; Wettability; Zein | 2019 |
Mixed micelles of TPGS and Soluplus
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Female; Fenretinide; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Micelles; Paclitaxel; Polyethylene Glycols; Polyvinyls; Rats; Rats, Wistar; Tumor Burden; Vitamin E; Xenograft Model Antitumor Assays | 2020 |
Paclitaxel-Loaded Colloidal Silica and TPGS-Based Solid Self-Emulsifying System Interferes Akt/mTOR Pathway in MDA-MB-231 and Demonstrates Anti-tumor Effect in Syngeneic Mammary Tumors.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biological Availability; Cell Line, Tumor; Colloids; Drug Delivery Systems; Emulsions; Humans; Mammary Neoplasms, Animal; Paclitaxel; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Research Design; Silicon Dioxide; TOR Serine-Threonine Kinases; Vitamin E | 2020 |
Chemosensitizing micelles self-assembled from amphiphilic TPGS-indomethacin twin drug for significantly synergetic multidrug resistance reversal.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Apoptosis; Cell Proliferation; Drug Liberation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Humans; Indomethacin; MCF-7 Cells; Micelles; Mitochondria; Paclitaxel; Reactive Oxygen Species; Vitamin E | 2021 |
Encapsulating Halofuginone Hydrobromide in TPGS Polymeric Micelles Enhances Efficacy Against Triple-Negative Breast Cancer Cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Compounding; Female; Humans; Membrane Potential, Mitochondrial; Mice, Inbred BALB C; Mice, Nude; Micelles; Paclitaxel; Piperidines; Polymers; Quinazolinones; Reactive Oxygen Species; Treatment Outcome; Triple Negative Breast Neoplasms; Vitamin E | 2021 |
Preparation and In Vitro/Vivo Evaluation of Folate-conjugated Pluronic F87-PLGA/TPGS Mixed Nanoparticles for Targeted Drug Delivery.
Topics: Apoptosis; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Female; Folic Acid; Humans; Nanoparticles; Ovarian Neoplasms; Paclitaxel; Poloxamer; Polyethylene Glycols; Vitamin E | 2021 |
Pterostilbene nanoparticles with small particle size show excellent anti-breast cancer activity
Topics: Animals; Antineoplastic Agents; Biological Availability; Breast Neoplasms; Drug Compounding; Female; HeLa Cells; Humans; Lecithins; MCF-7 Cells; Mice; Mice, Inbred BALB C; Nanoparticles; Paclitaxel; Particle Size; Solubility; Stilbenes; Treatment Outcome; Tumor Burden; Vitamin E; Xenograft Model Antitumor Assays | 2021 |
TPGS and chondroitin sulfate dual-modified lipid-albumin nanosystem for targeted delivery of chemotherapeutic agent against multidrug-resistant cancer.
Topics: Albumins; Animals; Breast Neoplasms; Cell Proliferation; Cell Survival; Chondroitin Sulfates; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Hyaluronan Receptors; Lipids; MCF-7 Cells; Mice; Nanoparticles; Paclitaxel; Vitamin E; Xenograft Model Antitumor Assays | 2021 |
Paclitaxel-Loaded TPGS
Topics: Biological Availability; Cell Line, Tumor; Cyclodextrins; Gelatin; HeLa Cells; Humans; Hyaluronic Acid; Nanoparticles; Paclitaxel; Vitamin E | 2022 |
Lipid- and TPGS-Based Core-Shell-Type Nanocapsules Endowed with High Paclitaxel Loading and Enhanced Anticancer Potential.
Topics: alpha-Tocopherol; Cell Line, Tumor; Humans; Lipids; Nanocapsules; Paclitaxel; Polyethylene Glycols; Vitamin E | 2022 |
Enhanced apoptosis and mitochondrial cell death by paclitaxel-loaded TPP-TPGS
Topics: Animals; Apoptosis; Cell Line, Tumor; Mice; Paclitaxel; Polyethylene Glycols; Tissue Distribution; Vitamin E | 2023 |