tocophersolan has been researched along with d-alpha tocopherol in 556 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (0.90) | 18.7374 |
| 1990's | 15 (2.70) | 18.2507 |
| 2000's | 60 (10.79) | 29.6817 |
| 2010's | 376 (67.63) | 24.3611 |
| 2020's | 100 (17.99) | 2.80 |
| Authors | Studies |
|---|---|
| Antapli, M; Hidiroglou, N; McDowell, LR; Papas, AM; Wilkinson, NS | 1 |
| Argao, EA; Heubi, JE; Hollis, BW; Tsang, RC | 1 |
| Johnson, KE; Kam, I; Karrer, FM; Narkewicz, MR; Smith, D; Sokol, RJ | 1 |
| Hidiroglou, M; Ivan, M | 1 |
| Boelsterli, UA; Göldlin, CR | 1 |
| Hawkey, CM; Jackson, SI; Kirkwood, JK; Markham, J | 1 |
| Carini, R; Cheeseman, KH; Dianzani, MU; Maddix, SP; Poli, G; Slater, TF | 1 |
| Accurso, F; Butler-Simon, N; Hammond, K; Heubi, JE; Heyman, M; Iannaccone, ST; McClung, HJ; Riely, C; Sinatra, F; Sokol, RJ | 1 |
| Kayden, HJ; Rindler, MJ; Thellman, CA; Traber, MG | 1 |
| Butler-Simon, N; Heubi, JE; Lilly, JR; McClung, HJ; Silverman, A; Sokol, RJ | 1 |
| Bettis, D; Butler-Simon, NA; Silverman, A; Smith, DJ; Sokol, RJ | 1 |
| Helson, C; Helson, L | 1 |
| Kayden, HJ; Schiano, TD; Shike, M; Steephen, AC; Traber, MG | 1 |
| Antapli, M; Hidiroglou, N; McDowell, LR; Papas, AM; Wilkinson, NS; Wolynetz, MS | 1 |
| Barker, DL; Ewan, RC; Mallarino, EG; Palo, PE; Piquer, FJ; Sell, JL; Soto-Salanova, MF | 1 |
| Blazek, J; Boudreaux, JP; Dick, D; Hayes, DH; Maggiore, P; Mizrahi, S | 1 |
| Butler-Simon, N; Conner, C; Heubi, JE; Heyman, MB; Levy, J; Perrault, J; Rothbaum, RJ; Sinatra, FR; Sokol, RJ; Suchy, FJ | 1 |
| Koletzko, B; Pawlowska, J; Proszynska, K; Socha, J; Socha, P | 1 |
| Dintaman, JM; Silverman, JA | 1 |
| Bridgers, A; Coffin, M; Long, S; Polli, J; Roy, A; Vickers, A; Winnike, R; Yu, L | 1 |
| McGinity, JW; Repka, MA | 1 |
| Wacher, VJ; Wong, HT; Wong, S | 1 |
| Bowman, RW; Cather, C; Cavanagh, HD; Fini, ME; Fisher, S; Gelender, H; Guidera, A; Hargrave, SL; Jester, JV; Jung, JC; McCulley, JP; Udell, I | 1 |
| Feng, SS; Mu, L | 3 |
| Kao, JP; Polli, JE; Rege, BD | 1 |
| Chai, A; Chan, AO; O'Mahony, D; Ramtoola, Z; Silverman, JA; Tran-Tau, P; Wacher, VJ; Wong, S; Yu, XQ | 1 |
| Bittner, B; Fullhardt, P; González, RC; Guenzi, A; Mountfield, RJ; Zuercher, G | 1 |
| Eaimtrakarn, S; Ishida, M; Prasad, YV; Puthli, SP; Shibata, N; Takada, K; Yoshikawa, Y | 1 |
| Kim, J; Shin, SC | 1 |
| Chen, LC; Chen, SY; Ho, HO; Sheu, MT | 1 |
| Sethia, S; Squillante, E | 1 |
| Samii, A; Walker, M | 1 |
| Alsenz, J; Bogman, K; Degen, L; Drewe, J; Gutmann, H; Hopfgartner, G; Zysset, Y | 1 |
| Ho, HO; Ke, WT; Lin, SY; Sheu, MT | 1 |
| Feng, SS; Mu, L; Ning, HZ; Tan, CS; Teo, MM | 1 |
| Alpar, OH; Bandera, M; Gradassi, G; Pandit, S; Ravichandran, E; Somavarapu, S | 1 |
| Basit, AW; Coffin, MD; Parsons, GE; Peters, EE; Schulze, JD; Staton, JS; Vickers, AW | 1 |
| Feng, SS; Zhang, Z | 2 |
| Choi, MK; Chung, JH; Kim, SH; Lee, CH; Lee, E; Lee, YJ; Lim, SJ; Youk, HJ | 1 |
| Corkill, M; Feranchak, AP; Gralla, J; King, R; Narkewicz, MR; Ramirez, RO; Sokol, RJ | 1 |
| Elbayoumi, TA; Mu, L; Torchilin, VP | 1 |
| Chen, CH; Ho, HO; Lin, KP; Sheu, MT; Wu, AB | 1 |
| Feng, SS; Win, KY | 1 |
| Baldes, C; Collnot, EM; Edgar, KJ; Hyatt, J; Lehr, CM; Navarro, L; Schaefer, UF; Wempe, MF | 1 |
| Mu, L; Seow, PH | 1 |
| Ho, HO; Lin, KP; Shen, CH; Sheu, MT; Wu, AB | 1 |
| Ashiru, DA; Basit, AW; Coffin, MD; Evans, DF; Khela, MK; Parsons, GE; Patel, R; Schulze, JD | 1 |
| Griffin, BT; O'Driscoll, CM | 1 |
| Barakat, NS | 1 |
| Feng, SS; Huey Lee, S; Zhang, Z | 1 |
| Kalbfleisch, J; Mohon, R; Papas, K | 1 |
| Conway, BR; Du, L; Nimmannit, U; Suppasansatorn, P; Wang, Y | 1 |
| Tan, EC; Yung, LY; Zhao, HZ | 1 |
| Dong, Y; Feng, SS; Zhang, Z | 1 |
| Chiappetta, D; Li, J | 1 |
| Armas, HN; D'Autry, W; Janssens, S; Nagels, S; Van den Mooter, G; Van Schepdael, A | 1 |
| Dai, WG; Deng, Z; Dong, LC; Li, S | 1 |
| Gao, Y; Li, LB; Zhai, G | 1 |
| Feng, SS; Pan, J | 2 |
| Bentley, MV; Casagrande, R; Fonseca, MJ; Georgetti, SR; Verri, WA; Vicentini, FT | 1 |
| Chang, YW; Chao, YS; Chen, CT; Chiang, TH; Ho, PY; Lin, HL; Lo, YK; Wu, HY; Wu, SH; Yao, HT; Yeh, TK | 1 |
| Goddeeris, C; Van den Mooter, G; Willems, T | 1 |
| Cao, N; Feng, SS | 1 |
| Chaw, CS; Yeung, E | 1 |
| Goddeeris, C; Van den Mooter, G | 1 |
| Goddeeris, C; Houthoofd, K; Martens, JA; Van den Mooter, G; Willems, T | 1 |
| Feng, SS; Pan, J; Wang, Y | 1 |
| Yung, LY; Zhao, H | 1 |
| Buchanan, CM; Caflisch, GB; Edgar, KJ; Large, SE; Lightner, JW; Little, JL; Rice, PJ; Ruble, KM; Wacher, VJ; Wempe, MF; Wright, C | 1 |
| Lau-Cam, CA; Sadoqi, M; Wu, SH | 1 |
| Jung, GY; Myung, PK; Na, YE; Park, CS; Park, MS | 1 |
| Bogatcheva, E; Einck, L; Nacy, CA; Nikonenko, BV; Protopopova, M; Reddy, VM | 1 |
| Dong, LF; Knötigová, P; Koudelka, S; Mahdavian, E; Neuzil, J; Procházka, L; Salvatore, BA; Sangsura, S; Turánek, J; Vacek, A; Vrublová, E; Wang, XF | 1 |
| Li, LB; Wang, J; Wang, R | 1 |
| Augustijns, P; Froyen, L; Houthoofd, K; Martens, JA; Mols, R; Van den Mooter, G; Van Eerdenbrugh, B; Van Humbeeck, J; Van Speybroeck, M | 1 |
| Chen, SY; Ho, HO; Liou, YB; Sheu, MT | 1 |
| Keck, CM | 1 |
| Jin, F; Tatavarti, A | 1 |
| Baldes, C; Collnot, EM; Edgar, KJ; Lehr, CM; Schaefer, UF; Wempe, MF | 1 |
| Anbharasi, V; Cao, N; Feng, SS | 1 |
| Chandran, T; Katragadda, U; Tan, C; Teng, Q | 1 |
| Feng, SS; Liu, Y; Pan, J | 1 |
| Damian, F; Fabian, J; Friend, DR; Kiser, PF | 1 |
| Cao, F; Cui, J; Gao, Y; Guo, C; Li, A; Li, H; Li, Z; Lou, H; Sun, M; Xi, Y; Zhai, G | 1 |
| Feng, SS; Zhao, L | 1 |
| Annaert, P; Augustijns, P; Brouwers, J; Mols, R | 1 |
| Hung, WC; Lai, PS; Li, PY; Syu, WJ | 1 |
| Augustijns, P; Froyen, L; Humbeeck, JV; Martens, JA; Van den Mooter, G; Van Eerdenbrugh, B; Vermant, J | 1 |
| Fricker, G; Hartmann, FJ; Parmentier, J | 1 |
| Bellare, JR; Dahe, GJ; Kadam, SS; Teotia, RS | 1 |
| Chen, CH; Chen, ET; Ho, HO; Ke, WT; Sheu, MT; Wei, JD | 1 |
| Liu, W; Nie, N; Song, N; Tu, Q; Wang, J; Zhang, Y | 1 |
| Dandekar, P; Hassan, PA; Jain, R; Pandey, U; Patravale, V; Samuel, G; Subramanian, S; Venkatesh, M | 1 |
| Bose, S; Ghosh, I; Harmon, F; Vippagunta, R | 1 |
| Backensfeld, T; Christiansen, A; Kühn, S; Weitschies, W | 1 |
| Feng, SS; Liu, Y; Mi, Y | 1 |
| Banerjee, R; Shah, AR | 1 |
| De Zordi, N; Macchiavelli, S; Moneghini, M; Princivalle, F; Solinas, D | 1 |
| Chen, HY; Hsu, CY; Huang, FH; Huang, LY; Lai, PS; Shieh, MJ | 1 |
| Cheow, WS; Hadinoto, K | 1 |
| Abela, AR; Duplais, C; Gadwood, RC; Gaston, RD; Ghorai, S; Krasovskiy, A; Lipshutz, BH; Moser, R; Nishikata, T | 1 |
| Chandrasekharan, P; Chuang, KH; Ding, J; Feng, SS; Maity, D; Yong, CX | 1 |
| Chen, W; Fan, DJ; Lin, X; Meng, LK; Miao, YQ; Tang, X; Yang, SS | 1 |
| Balakrishnan, P; Cho, HJ; Chung, SJ; Kim, DD; Shim, CK | 1 |
| Charkoftaki, G; Dokoumetzidis, A; Macheras, P; Valsami, G | 1 |
| Chandran, T; Katragadda, U; Rayaprolu, BM; Tan, C; Teng, Q | 1 |
| Chen, H; Huang, L; Liu, K; Liu, R; Mei, L; Song, X; Zeng, X; Zheng, Y | 1 |
| Feng, SS; Kulkarni, SA; Muthu, MS; Xiong, J | 1 |
| Bao, ZB; Kong, LY; Ren, QL; Su, BG; Xing, HB; Yang, YW | 1 |
| Chen, YC; Ho, HO; Ke, WT; Lin, YM; Sheu, MT; Su, YD; Wu, JY | 1 |
| Benhabbour, SR; Feng, L; Ma, P; Mumper, RJ; Wu, H | 1 |
| Baek, JS; Cho, CW; Hwang, CJ; Keum, CG; Lim, JH; Na, YG; Noh, YW; Shin, SC | 1 |
| Aggarwal, N; Goindi, S; Mehta, SD | 1 |
| Bauer-Brandl, A; di Cagno, M; Hlaváč, J; Skalko-Basnet, N; Stein, PC; Styskala, J | 1 |
| Brueggemeier, RW; Kanthamneni, N; Lee, LJ; Lee, RJ; Mao, Y; Sugimoto, Y; Yu, B; Zhang, Y; Zhou, C | 1 |
| Feng, SS; Liu, Y; Mi, Y; Zhao, J | 1 |
| Constantinou, AI; Constantinou, C; Hyatt, JA; Neophytou, CM; Papas, KA; Vraka, P | 1 |
| Cao, W; He, ZG; Lian, H; Liu, YH; Sun, J; Sun, YH; Wang, SL; Wang, YJ; Yu, YP | 1 |
| Ghosh, I; Michniak-Kohn, B | 2 |
| Feng, SS; Kulkarni, SA; Muthu, MS; Raju, A | 1 |
| Feng, SS; Kulkarni, SA; Liu, Y; Muthu, MS | 1 |
| Hussain, MD; Saxena, V | 2 |
| Gill, KK; Kaddoumi, A; Nazzal, S | 1 |
| Jia, X; Lingling, C; Lv, H; Sun, E; Tan, X; Xin, J; Yan, C; Zhang, Z | 1 |
| Amighi, K; Duret, C; Sebti, T; Vanderbist, F; Wauthoz, N | 1 |
| Feng, SS; Tan, S; Zhang, Z | 1 |
| Bajaj, A; Khole, I; Munjapara, G; Rao, MR | 1 |
| Lu, Y; Shan, W; Wang, T; Xiong, S; Yin, X | 1 |
| Rayaprolu, BM; Strom, JG | 1 |
| He, Z; Liu, H; Sun, J; Wang, Y; Xu, H | 1 |
| Gu, Y; Meng, L; Ren, T; Tang, X; Tian, B; Wang, X; Zhang, Y | 1 |
| Addai-Mensah, J; Losic, D; Sinn Aw, M | 1 |
| Bansal, AK; Lale, SV; Munjal, B; Patel, SB; Pawar, YB; Purohit, H; Valicherla, GR | 1 |
| Palm, AS; Šašić, S; Tang, D | 1 |
| Bezerra, JA; Haber, B; Karpen, SJ; Kerkar, N; Magee, JC; Raghunathan, T; Robuck, PR; Rosenthal, P; Schwarz, K; Shneider, BL; Sokol, RJ; Suchy, FJ; Turmelle, Y; Whitington, PF | 1 |
| Chen, L; Li, Y; Shen, J; Yin, Q; Zhang, Z | 1 |
| Bose, S; Ghosh, I; Ruegger, C; Schenck, D | 1 |
| Feng, SS; Mi, Y; Zhao, J | 3 |
| Gershkovich, P; Ibrahim, F; Sivak, O; Wasan, EK; Wasan, KM | 1 |
| Ceresara, G; Fogagnolo, P; Lapadula, P; Orzalesi, N; Paderni, R; Rossetti, L; Sacchi, M | 1 |
| Brownlow, B; Elbayoumi, T; Jordan, M; Nayel, A | 1 |
| Caruso, C; Del Prete, A; Laneri, S; Ostacolo, C; Pacente, L; Sacchi, A; Troisi, S; Tronino, D | 1 |
| Al Shaal, L; Keck, CM; Müller, RH; Rachmawati, H | 1 |
| Lee, EH; Lim, SJ | 1 |
| Jia, XB; Jin, X; Sun, E; Tan, XB; Zhang, ZH; Zhu, FX | 1 |
| George, M; Ghosh, I | 1 |
| Bindra, DS; Gour, S; Hamey, R; Pandey, P; Sinko, PD; Vema-Varapu, C | 1 |
| Li, Y; Shen, J; Sun, H; Wang, S; Xu, P; Yin, Q; Yu, H; Zhang, Z | 1 |
| Ding, LY; Guo, M; Liu, YQ; Lu, Y; Ron, WT; Song, FF; Wang, Y; Yu, SQ | 1 |
| Feng, SS; Mei, L; Zhang, Z | 1 |
| Hu, PY; Li, Y; Ma, YQ; Wan, J; Wang, CH; Wang, Y; Yang, M; Yuan, HL; Yue, PF | 1 |
| Cho, WK; Hwang, SJ; Kim, JS; Kim, MS | 1 |
| Aw, MS; Losic, D | 1 |
| Feng, SS; Kulkarni, SA | 1 |
| di Cagno, M; Luppi, B | 1 |
| Fan, L; He, C; Mo, X; Sheng, X; Wang, H; Zhang, K | 1 |
| Fan, Z; Fang, X; Sha, X; Wu, J | 1 |
| Cha, KH; Cho, W; Hwang, SJ; Kim, JS; Kim, MS; Park, HJ; Park, J | 1 |
| Huang, B; Liu, CS; Wang, G; Wu, Y; Yu, B; Yuan, Y | 1 |
| Alany, RG; Chen, JJ; Falconer, JR; Farid, M; Tallon, SJ; Wen, J; Zargar-Shoshtari, S | 1 |
| Alany, RG; Chen, JJ; El Maghraby, GM; Falconer, JR; Farid, M; Wen, J; Zargar-Shoshtari, S | 1 |
| Feng, SS; Muthu, MS; Raju, A | 1 |
| Fu, Q; Liu, F; Racette, K; Ramishetti, S; Tang, J; Wang, D; Wang, Y | 1 |
| Guo, Y; Luo, J; Otieno, BO; Tan, S; Zhang, Z | 1 |
| Gu, L; Zou, T | 1 |
| McKelvey, C; Moser, J; Rege, B; Sotthivirat, S; Xu, W; Zhang, D | 1 |
| Chen, H; Dong, Y; Huang, H; Zhang, J; Zhang, W; Zhao, T; Zhu, J | 1 |
| Bandari, S; Eedara, BB; Jukanti, R; Veerareddy, PR | 1 |
| Chu, M; Guo, Y; Huang, J; Liu, H; Tan, S; Zhang, Z; Zhao, S | 1 |
| Huang, L; Liu, T; Mei, L; Ouyang, C; Tao, W; Wang, Z; Xiong, Q; Zeng, X | 1 |
| Chen, L; Li, Y; Shen, J; Xu, P; Yin, Q; Yu, H; Zhang, Z | 1 |
| Gao, L; Kang, J; Liu, G; Ma, J; Niu, M; Wang, H; Wang, X; Wang, Z | 1 |
| Bu, S; Jiang, L; Xie, X; Yang, C; Zeng, Q; Zhang, L; Zheng, Y; Zhu, D | 1 |
| Bernabeu, E; Chiappetta, DA; Gonzalez, L; Helguera, G; Hocht, C; Legaspi, MJ; Taira, C | 1 |
| Dou, J; Liu, X; Zhai, G; Zhang, H; Zhang, M | 1 |
| Cholkar, K; Mitra, AK; Vadlapatla, RK; Vadlapudi, AD | 1 |
| Hascicek, C; Oz, UC; Serim, TM; Turk, CT | 1 |
| Chu, M; Guo, Y; Liu, H; Otieno, BO; Tan, S; Xu, C; Yang, X; Zhang, Z; Zhao, S | 1 |
| Li, Y; Meng, Q; Shen, J; Sui, H; Yin, Q; Yu, H; Zhang, Z | 1 |
| Abbad, S; Baraza, LD; Lv, H; Munyendo, WL; Waddad, AY; Zhang, Z; Zhou, J | 1 |
| Mosquera-Giraldo, LI; Taylor, LS; Trasi, NS | 1 |
| Bera, T; Das, S; Halder, A; Mondal, S; Mukherjee, A; Roy, P | 1 |
| Bristow, A; Kilgour, D; McBride, E; O'Connor, PB; Wei, J | 1 |
| Feng, SS; Leong, DT; Tan, GR | 1 |
| Klumphu, P; Lipshutz, BH | 1 |
| Chen, Y; Deng, J; Jia, X; Lv, H; Zhang, Z; Zhou, J | 1 |
| Jin, L; Shan, W; Shu, D; Wang, H; Wang, T; Wu, J; Xiong, S; Zhang, S | 1 |
| Cho, HJ; Kim, DD; Park, JW; Yoon, IS | 1 |
| Constantinou, AI; Constantinou, C; Neophytou, CM; Papageorgis, P | 1 |
| Dai, X; Fan, W; Katragadda, U; Mckinley, D; Tan, C; Teng, Q; Wang, Y | 1 |
| Cui, J; Gu, W; Jiang, S; Li, Y; Liu, Z; Niu, B; Zhang, Z | 1 |
| Jain, NK; Mehra, NK; Mishra, PR; Verma, AK | 1 |
| Ali, J; Baboota, S; Sahni, JK; Sharma, S | 1 |
| Fallon, JK; Fu, Q; He, Z; Liu, D; Liu, F; Ma, Y; Wang, D; Wang, Y; Yang, X | 1 |
| Furuno, T; Kurimoto, I; Obata, T; Ogawa, N; Sasaki, T; Suzuki, Y; Tanaka, M; Yamamoto, H | 1 |
| Abdulla, A; Kaklotar, D; Muthu, MS; Pandey, BL; Rajesh, CV; Sahu, AK; Singh, S | 1 |
| Bu, H; He, X; Li, Y; Yin, Q; Yu, H; Zhang, Z | 1 |
| Ji, H; Li, M; Ren, J; Tang, J; Wu, L; Zheng, N | 1 |
| Shen, M; Shi, X; Tang, Y; Wen, S; Zhang, G; Zheng, L; Zhu, J | 1 |
| Ai, X; Ding, W; Han, X; He, Z; Lian, H; Niu, H; Pu, X; Ren, G; Sun, J; Wang, J; Wu, C; Xu, T; Zhong, L | 1 |
| Cholkar, K; Gunda, S; Hariharan, S; Mitra, AK | 1 |
| Bao, X; Chu, QC; Gao, M; Guan, X; Jiang, N; Liu, KX; Tian, Y; Xu, H; Zhang, CH | 1 |
| Jin, J; Li, C; Liu, J; Xu, X; Yin, J | 1 |
| Chen, D; Chen, G; Huang, S; Li, T; Lv, Z; Song, F; Yang, F; Yang, L; Yu, A; Yu, X; Zhang, Y; Zhu, W | 1 |
| Kulhari, H; Mukherjee, S; Pooja, D; Rachamalla, SS; Singh, MK; Sistla, R | 1 |
| Fang, Z; Lou, H; Ren, M; Sun, D; Wei, X; Xue, X; Zhang, X | 1 |
| Cui, Y; Li, L; Li, Y; Zhao, Y | 1 |
| Chen, YC; Chiou, JD; Ho, HO; Sheu, MT | 1 |
| Bao, Y; Cheng, B; Guo, Y; Li, D; Tan, S; Zhang, Z; Zhuang, X | 1 |
| Ahmad, FJ; Anwar, M; Garg, V; Jain, GK; Khar, RK; Talegaonkar, S; Warsi, MH | 1 |
| Baek, IH; Cho, W; Choo, GH; Ha, ES; Hwang, SJ; Jin, SE; Jung, YS; Kim, JS; Kim, MS | 1 |
| Chen, D; Chen, Q; Cheng, L; Hu, H; Hu, W; Li, G; Li, Z; Long, M; Qiao, M; Qiu, L; Tian, C; Wang, M; Zhao, X | 1 |
| Guo, Y; Si, L; Song, Q; Tan, S; Wu, T; Ye, Q; Zhang, Z; Zhao, Y; Zhuang, X | 1 |
| Chen, M; Fang, X; Li, Y; Wang, Y; Zhang, J; Zhou, D | 1 |
| Chen, D; Chen, Q; Hao, T; Hu, H; Li, Z; Mei, L; Qiao, M; Qiu, L; Zhang, J; Zhao, H; Zhao, X | 1 |
| Danhier, F; Draoui, N; Duhem, N; Feron, O; Kouhé, TT; Préat, V; Staub, A; Ucakar, B | 1 |
| Bernabeu, E; Chiappetta, DA; Flor, S; Höcht, C; Lucangioli, S; Moretton, MA; Taira, C | 1 |
| Correia, IJ; Costa, EC; de Melo-Diogo, D; Gallardo, E; Gaspar, VM; Moreira, AF; Oppolzer, D | 1 |
| Bristow, AW; O'Connor, PB; Wei, J | 1 |
| Baumgart, BR; Bunch, RT; Davies, MH; Donegan, M; Lange, RW; Lentz, K; Salcedo, TW; Sanderson, TP; Simic, D; Van Vleet, TR | 1 |
| Chen, M; Chen, R; Morott, J; Repka, MA; Wang, S; Wang, Y | 1 |
| Cholkar, K; Earla, R; Gunda, S; Mitra, AK; Pal, D | 1 |
| Gu, Z; Tian, G; Wang, D; Yang, X; Yin, W; Yu, J; Zhang, X; Zhang, Z; Zhao, Y; Zheng, X | 1 |
| Baek, IH; Cho, W; Choo, GH; Ha, ES; Hwang, SJ; Jeong, HY; Jung, YS; Kim, JS; Kim, MS; Noh, J; Ok, J | 1 |
| Chen, Y; Lee, RJ; Sun, Y; Tang, S; Teng, L; Wang, G; Wu, Y; Xu, S; Yu, B; Yuan, Y; Zhang, X | 1 |
| Feng, SS; Kutty, RV; Luo, Z; Muthu, MS; Xie, J | 1 |
| Cai, S; Hou, W; Liu, F; Sun, L; Tang, X; Zhang, R; Zhu, H | 1 |
| Chen, X; Cui, H; Cui, Z; Guo, C; Li, Y; Yang, X; Yin, Q; Yu, H; Yu, P; Zhang, P | 1 |
| Han, HK; Shao, Y; Yang, L | 1 |
| Abbad, S; Lv, H; Waddad, AY; Wang, C; Zhou, J | 1 |
| Gao, Y; Li, J; Li, X; Liu, Y; Ma, S; Wang, D; Zhang, C; Zhao, L; Zhao, Y; Zhou, Y | 1 |
| Hou, J; Lu, Y; Qi, SS; Rong, WT; Wang, DF; Xiao, Q; Xu, Q; You, J; Yu, SQ; Zhang, J | 1 |
| Feng, X; Jin, X; Liang, Y; Sun, L; Tang, X; Zhang, R | 1 |
| Cai, X; Du, H; Duan, Y; Zhai, G | 1 |
| Butt, AM; Katas, H; Mohd Amin, MC | 1 |
| Chen, Y; Li, X; Li, Z; Mei, L; Xu, G; Yan, M; Zheng, Y; Zhou, Y | 1 |
| Chen, H; Hu, B; Hu, Y; Li, S; Qiu, L; Wu, X; Zheng, Y | 1 |
| Atef, E; Karzuon, B; Raut, S | 1 |
| Ishak, RA; Osman, R | 1 |
| Chang, D; Chen, Y; Huang, L; Mei, L; Tao, W; Wang, T; Zeng, X; Zhang, J; Zhang, X | 1 |
| Huang, L; Liu, D; Liu, G; Liu, Y; Mei, L; Tao, W; Yu, Q; Zeng, X; Zhang, J; Zhu, X | 1 |
| Balasubramanian, S; Malathi, S; Nandhakumar, P; Pandiyan, V; Webster, TJ | 1 |
| Huang, L; Liu, G; Mei, L; Wang, Z; Wu, Y; Yang, C; Zeng, X; Zhang, H | 1 |
| Deka, SR; Mahato, M; Rai, V; Sharma, AK; Singh, M; Yadav, S | 1 |
| Liang, DS; Liu, YJ; Qi, XR; Wang, AT | 1 |
| Adams, DJ; Barui, AK; Kulhari, H; Naidu Vegi, GM; Patra, CR; Pooja, D; Shrivastava, S; Sistla, R; Telukutala, SR | 1 |
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| Ahmed, OAA; Alhakamy, NA; Fahmy, UA | 1 |
| Cao, X; Choi, G; Choy, JH; Guo, R; Jiang, T; Shi, X; Sun, W; Zhang, C | 1 |
| Chen, Y; Feng, X; Li, L; Zhang, L; Zhang, Y; Zhang, Z | 1 |
| Ahmad, FJ; Akhter, S; Garg, N; Kumar Jain, G; Selvapandiyan, A; Zafar, S | 1 |
| Fu, T; Gu, X; Liu, Q; Peng, X; Yang, J | 1 |
| Adu-Frimpong, M; Deng, W; Li, W; Li, Y; Ma, P; Sun, C; Xu, X; Yu, J; Zhang, H; Zhu, Y | 1 |
| Fernández-Rubio, C; González-Benito, J; González-Gaitano, G; Houston, JE; Nguewa, P; Puig-Rigall, J; Radulescu, A | 1 |
| Malathi, S; Pavithra, PS; Sridevi, S; Verma, RS | 1 |
| Gou, G; Li, N; Liu, Q; Mai, Y; Yang, J | 1 |
| Gao, J; Liu, J; Lu, Y; Shen, X; Xie, F; Yin, C | 1 |
| Caporossi, A; Fasciani, R; Gambini, G; Tredici, C; Villano, A | 1 |
| Bai, Y; Chen, L; Fakhri, GE; Gao, H; Wang, M | 1 |
| He, K; Jiang, M; Li, J; Liu, Q; Qiu, T; Sun, J; Yang, M; Zhan, S; Zhang, X | 1 |
| Chu, Q; Kong, L; Qin, X; Tu, J; Tu, K; Wang, L; Xu, H; Yuan, X; Zhang, Z | 1 |
| Li, G; Li, R; Liu, S; Qian, J; Shen, J; Sun, J; Xie, Y | 1 |
| Bai, R; Bi, F; Liu, J; Qin, Y; Yong, H | 1 |
| Li, X; Li, Z; Lian, D; Liu, J; Ye, L | 1 |
| Guan, Q; Huang, L; Liu, Y; Qiao, J; Wang, N; Wu, J; Yu, D; Yu, S; Zhang, G | 1 |
| Baek, JS; Byeon, JJ; Cho, CW; Han, MG; Kim, MK; Lee, HK; Na, YG; Pham, TMA | 1 |
| He, L; Sun, M; Tang, R; Wang, X | 1 |
| Ding, Y; Gao, M; Li, L; Ma, C; Ma, X; Wang, C; Wang, Y; Xu, Y | 1 |
| Bai, P; Chen, L; Liu, H; Qiu, N; Shu, X; Wang, Z; Wen, J; Yang, L; Zhu, Z | 1 |
| Bao, YL; Ding, MH; Guan, Y; Tan, SW; Wang, B; Wang, LY | 1 |
| Chen, H; Li, W; Lu, Y; Tao, R; Wang, C; Zhang, C; Zhou, H | 1 |
| Awad, GAS; El-Borady, OM; Elhabak, M; Mohamed, M; Mortada, N; Osman, R | 1 |
| Chen, S; Cui, Q; Wande, DP; Xiong, H; Xu, C; Yao, J | 1 |
| Kurmi, BD; Paliwal, R; Paliwal, SR; Tekchandani, P | 1 |
| Mahajan, HS; Patil, PH | 1 |
| Chen, J; Cheng, B; Li, D; Liu, D; Pan, H; Pan, W; Qiao, S; Wu, Q | 1 |
| Cheng, X; He, L; Song, J; Sun, M; Tang, R; Wang, X; Wei, B; Xiong, N; Xu, J | 1 |
| Charalambous, C; Constantinou, AI; Constantinou, C; Kanakis, D; Kolokotroni, O | 1 |
| Fang, J; Li, Q; Li, X; Wang, J; Wu, X; Xin, M; Yang, H | 1 |
| Li, L; Liao, JX; Liu, T; Song, DB; Wang, GH; Zhang, ZY | 1 |
| Blanco-Prieto, MJ; Dreiss, CA; González-Gaitano, G; Puig-Rigall, J; Radulescu, A | 1 |
| Adu-Frimpong, M; Chen, B; Deng, W; Sun, C; Xu, X; Yu, J; Zhang, H; Zhu, Y | 1 |
| Abagyan, R; Feng, J; He, X; Liu, Y; Shi, D; Xiang, T; Yan, S; Zhang, J; Zhang, Y; Zhong, C | 1 |
| Alshehri, S; Altamimi, MA; Alzahrani, TA; Hussain, A; Imam, SS | 1 |
| Chourasia, MK; Dixit, S; Konwar, R; Meher, JG; Pawar, VK; Saklani, R; Singh, Y | 1 |
| Han, S; Mutlu-Agardan, NB | 1 |
| Bahadur, P; Rathod, S; Tiwari, S | 1 |
| Chen, R; Kuang, X; Tang, R; Wang, X; Wang, Z; Wu, S; Yan, G | 1 |
| Ahsan, A; Farooq, MA; Jabeen, A; Kutoka, PT; Seidu, TA; Wang, B; Xinyu, H | 1 |
| Blond, E; Bordat, C; Cuerq, C; Halimi, C; Nowicki, M; Peretti, N; Reboul, E | 1 |
| Li, D; Liu, S; Shen, L; Zhang, QY; Zhu, H; Zhu, J | 1 |
| Beig, A; Dahan, A; Fine-Shamir, N | 1 |
| Du, X; Gao, N; Song, X | 1 |
| Choudhury, H; Gorain, B; Kokare, CR; Kumbhar, SA; Shrivastava, B | 1 |
| Flora, SJS; Kumar, A; Shukla, R; Singh, A | 1 |
| Fang, K; Gao, X; Guo, D; Hu, S; Ji, C; Ji, H; Jiang, S; Li, G; Peng, L; Si, H; Song, X; Wang, J; Zhang, J; Zuo, R | 1 |
| Kurmi, BD; Paliwal, SR | 1 |
| Afanador, N; Brown, C; Ren, J; Rosenberg, K; Skomski, D; Sotthivirat, S; Taggart, RV; Wasylaschuk, W | 1 |
| Gong, Y; Li, Y; Li, Z; Wu, T; Xiong, X | 1 |
| Chen, H; Chen, Y; Li, CH; Quan, G; Wang, Q; Wang, Z; Wu, P; Xie, D; Xu, J; Yang, L; Zhang, J | 1 |
| Agrawal, N; Azad, S; Jha, A; Mahto, SK; Muthu, MS; Poddar, S; Viswanadh, MK | 1 |
| Bi, D; Feng, L; Fu, J; Guo, Y; Han, J; Han, M; Wang, X; Zou, Y | 1 |
| Abriata, JP; Chorilli, M; Emery, FDS; Luiz, MT; Marchetti, JM; Tofani, LB; Vaidergorn, MM; Viegas, JSR | 1 |
| Li, J; Luo, K; Wang, G; Xu, F; Yao, T; Yu, H; Zhu, J | 1 |
| Fan, Y; Feng, N; Guo, T; Lu, J; Sha, X; Yin, S; Zhang, Y | 1 |
| Amin, PD; Shinde, UK; Suryawanshi, DG | 1 |
| Du, X; Wang, R; Yan, H; Zhai, G | 1 |
| Fan, Z; Fu, X; Ge, D; Hou, Z; Shi, D; Su, G; Yang, Y; Zhao, Q; Zheng, K | 1 |
| Alam Rizvi, MM; Amin, S; Mir, SR; Perwez, A; Rizwanullah, M | 1 |
| Asrat, H; Boinapally, N; Hawkey, A; Holloway, Z; Levin, ED | 1 |
| Du, Z; Fu, J; Hu, J; Mao, Y; Yin, J; You, Q; Zhang, P | 1 |
| Qi, M; Zhao, H | 1 |
| Huang, QF; Jiang, YY; Liu, M; Lu, XX; Shao, CL; Wang, GH; Zhang, JM | 1 |
| Abdelmonsif, DA; Aly, RG; Elgindy, NA; Mohyeldin, SM; Ragab, D; Samy, WM | 1 |
| Deng, Y; Liu, M; Liu, X; Song, Y; Su, Y; Sun, J; Tian, Q | 1 |
| Cai, R; Liu, Y; Song, T; Wang, H; Xiong, Y; Yang, D | 1 |
| Chen, G; Li, H; Liu, M; Lu, W; Svirskis, D; Wen, J; Ying, M | 1 |
| Abd-Elsalam, WH; Ibrahim, RR | 1 |
| da Silva Neto, MR; de Gomes, MG; de Oliveira Pacheco, C; Dos Santos, RB; Giacomeli, R; Haas, SE; Maciel, TR; Parisotto, AJM; Ribeiro, ACF | 1 |
| Hua, D; Li, S; Tong, M; Wang, J; Wu, X; Yu, X; Zhang, S; Zhang, Z | 1 |
| Bai, R; Jian, L; Ren, T; Yang, Y; Zheng, X | 1 |
| Açıkalın, A; Dağlıoğlu, YK; Oruz, O; Polat, S; Şaker, D; Yar, K | 1 |
| Indulkar, AS; Lou, X; Taylor, LS; Zhang, GGZ | 1 |
| Chinni, S; Kala, SG | 1 |
| Chen, J; Ding, W; Feng, J; Li, F; Li, Y; Liang, D; Tang, L; Xie, T; Yang, X; Zhang, Z; Zou, L | 1 |
| Amin, MM; Fayad, W; Hegazy, H; Zakaria, MY | 1 |
| Gui, S; Guo, J; He, N; Huang, Y; Li, Z; Liang, X; Tang, M; Tao, Y | 1 |
| Jimenez-Del-Rio, M; Mendivil-Perez, M; Velez-Pardo, C | 1 |
| Chen, X; Fang, K; Gao, X; Gong, J; Guo, D; Hu, S; Ji, H; Jiang, S; Lv, Y; Peng, L; Song, X; Yang, F; Zhang, J; Zhang, Y; Zuo, R | 1 |
| Chen, N; Du, Y; Hong, D; Jiang, S; Li, L; Lu, X; Ma, K; Sun, Y; Wang, X; Xu, X; Zhang, S | 1 |
| Dora, CP; Ghadi, R; Jain, S; Katiyar, SS; Kuche, K; Kushwah, V; Patil, R | 1 |
| Basu Baul, TS; Koch, B; Singh, M; Singh, V | 1 |
| Gao, T; Ma, S; Mai, Y; Yang, J; Yu, N; Yu, R | 1 |
| De Caro, L; Giannini, C; Giudice, AD; Gozzo, F; Grandeury, A; Morin, M; Reinle-Schmitt, M | 1 |
| Gu, L; Wang, GP; Yagiz, Y | 1 |
| Farooq, MA; Trevaskis, NL | 1 |
| Deng, Y; Qi, Z; Shi, J; Song, Y | 1 |
| Chauhan, D; Chourasia, MK; Gayen, JR; Kalleti, N; Kedar, AS; Mishra, K; Mitra, K; Mugale, MN; Rana, R; Rath, SK; Saklani, R; Sharma, D; Tiwari, AK; Verma, S; Wahajuddin, M; Yadav, P; Yadav, PK | 1 |
| Balıkçı, AT; Ulutaş, HG | 1 |
| Attia, Y; El-Nabarawi, M; Mahmoud, K; Swidan, S; Teaima, M | 1 |
| DU, Z; Zhang, D | 1 |
| Bhattacharya, S; Hatware, K; Jain, A; Manthalkar, L; Phatak, N; Shah, D; Sreelaya, P | 1 |
14 review(s) available for tocophersolan and d-alpha tocopherol
| Article | Year |
|---|---|
Vitamin E TPGS as a molecular biomaterial for drug delivery.
Topics: Animals; Biocompatible Materials; Drug Delivery Systems; Humans; Liposomes; Micelles; Nanoparticles; Polyethylene Glycols; Vitamin E | 2012 |
The applications of Vitamin E TPGS in drug delivery.
Topics: Animals; Chemistry, Pharmaceutical; Drug Delivery Systems; Humans; Polyethylene Glycols; Vitamin E; Vitamins | 2013 |
Current trends in the use of vitamin E-based micellar nanocarriers for anticancer drug delivery.
Topics: alpha-Tocopherol; Antineoplastic Agents; Drug Carriers; Drug Delivery Systems; Drug Resistance, Multiple; Humans; Hydrophobic and Hydrophilic Interactions; Micelles; Nanoparticles; Neoplasms; Solubility; Vitamin E | 2017 |
Recent advances in TPGS-based nanoparticles of docetaxel for improved chemotherapy.
Topics: Cell Line, Tumor; Docetaxel; Drug Carriers; Humans; Nanoparticles; Polyethylene Glycols; Taxoids; Vitamin E | 2017 |
Recent developments in d-α-tocopheryl polyethylene glycol-succinate-based nanomedicine for cancer therapy.
Topics: Animals; Drug Carriers; Drug Delivery Systems; Humans; Nanomedicine; Neoplasms; Vitamin E | 2017 |
Recent Advances in the Application of Vitamin E TPGS for Drug Delivery.
Topics: Animals; Drug Delivery Systems; Drug Resistance, Multiple; Humans; Nanomedicine; Solubility; Vitamin E | 2018 |
Paclitaxel loaded vitamin E-TPGS nanoparticles for cancer therapy.
Topics: Animals; Drug Delivery Systems; Humans; Nanoparticles; Nanotechnology; Neoplasms; Paclitaxel; Vitamin E | 2018 |
Iron Transport Tocopheryl Polyethylene Glycol Succinate in Animal Health and Diseases.
Topics: Animals; Biological Availability; Conalbumin; Drug Compounding; Drug Delivery Systems; Gastrointestinal Tract; Iron; Stomach Diseases; Vitamin E | 2019 |
Recent Advances of D-α-tocopherol Polyethylene Glycol 1000 Succinate Based Stimuli-responsive Nanomedicine for Cancer Treatment.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Carriers; Drug Resistance, Neoplasm; Drug Synergism; Humans; Nanoparticles; Neoplasms; Vitamin E | 2020 |
Rediscovering Tocophersolan: A Renaissance for Nano-Based Drug Delivery and Nanotheranostic Applications.
Topics: Drug Delivery Systems; Excipients; Humans; Nanoparticles; Polymers; Theranostic Nanomedicine; Vitamin E | 2021 |
Update on the Anti-Cancer Potency of Tocotrienols and α-Tocopheryl Polyethylene Glycol 1000 Succinate on Leukemic Cell Lines.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line; Cell Line, Tumor; Humans; Polyethylene Glycols; Succinates; Tocotrienols; Vitamin E | 2021 |
Nanocarriers based on vitamin E-TPGS: Design principle and molecular insights into improving the efficacy of anticancer drugs.
Topics: Antineoplastic Agents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Micelles; Polyethylene Glycols; Vitamin E | 2021 |
Progress in the study of D-α-tocopherol polyethylene glycol 1000 succinate (TPGS) reversing multidrug resistance.
Topics: alpha-Tocopherol; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Polyethylene Glycols; Succinates; Vitamin E | 2021 |
TPGS Decorated Liposomes as Multifunctional Nano-Delivery Systems.
Topics: alpha-Tocopherol; Humans; Liposomes; Nanoparticle Drug Delivery System; Neoplasms; Polyethylene Glycols; Vitamin E | 2023 |
10 trial(s) available for tocophersolan and d-alpha tocopherol
| Article | Year |
|---|---|
Improvement of cyclosporin absorption in children after liver transplantation by means of water-soluble vitamin E.
Topics: Adult; Child; Child, Preschool; Cyclosporins; Humans; Immunosuppression Therapy; Infant; Intestinal Absorption; Lipids; Liver Diseases; Liver Transplantation; Polyethylene Glycols; Vitamin E | 1991 |
Multicenter trial of d-alpha-tocopheryl polyethylene glycol 1000 succinate for treatment of vitamin E deficiency in children with chronic cholestasis.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Cholestasis; Chronic Disease; Copper; Female; Humans; Infant; Male; Polyethylene Glycols; Stereoisomerism; Vitamin E; Vitamin E Deficiency | 1993 |
P-glycoprotein and surfactants: effect on intestinal talinolol absorption.
Topics: Adrenergic beta-Agonists; Adult; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Caco-2 Cells; Cross-Over Studies; Drug Interactions; Half-Life; Humans; Intestinal Absorption; Male; Permeability; Poloxamer; Polyethylene Glycols; Propanolamines; Surface-Active Agents; Vitamin E | 2005 |
Comparison of indices of vitamin A status in children with chronic liver disease.
Topics: Administration, Oral; Adolescent; Adult; Child; Child, Preschool; Cholestasis; Chronic Disease; Diterpenes; Dry Eye Syndromes; Female; Humans; Infant; Liver Diseases; Male; Polyethylene Glycols; Retinol-Binding Proteins; Retinyl Esters; Sensitivity and Specificity; Vitamin A; Vitamin A Deficiency; Vitamin E | 2005 |
Bioavailability of a novel, water-soluble vitamin E formulation in malabsorbing patients.
Topics: Adolescent; Adult; alpha-Tocopherol; Antioxidants; Area Under Curve; Biological Availability; Chemistry, Pharmaceutical; Child; Cystic Fibrosis; Dosage Forms; gamma-Tocopherol; Humans; Intestinal Absorption; Lipids; Malabsorption Syndromes; Polyethylene Glycols; Solubility; Solvents; Tocopherols; Vitamin E; Water | 2007 |
Preparation and evaluation of dermal delivery system of griseofulvin containing vitamin E-TPGS as penetration enhancer.
Topics: Administration, Cutaneous; Adult; Animals; Drug Evaluation, Preclinical; Female; Griseofulvin; Humans; Male; Mice; Mycoses; Patch Tests; Polyethylene Glycols; Skin Absorption; Vitamin E; Young Adult | 2012 |
Efficacy of fat-soluble vitamin supplementation in infants with biliary atresia.
Topics: alpha-Tocopherol; Avitaminosis; Biliary Atresia; Bilirubin; Dietary Supplements; Double-Blind Method; Female; Humans; Infant; Male; Polyethylene Glycols; Portoenterostomy, Hepatic; Postoperative Care; Retinol-Binding Proteins; Vitamin A; Vitamin D; Vitamin E; Vitamin K | 2012 |
The effects of topical coenzyme Q10 and vitamin E D-α-tocopheryl polyethylene glycol 1000 succinate after cataract surgery: a clinical and in vivo confocal study.
Topics: Administration, Topical; Aged; Cataract Extraction; Drug Carriers; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Microscopy, Confocal; Ophthalmic Solutions; Polyethylene Glycols; Postoperative Care; Postoperative Complications; Retrospective Studies; Treatment Outcome; Ubiquinone; Vitamin E; Vitamins; Wound Healing | 2013 |
Transepithelial Corneal Cross-Linking With Vitamin E-Enhanced Riboflavin Solution and Abbreviated, Low-Dose UV-A: 24-Month Clinical Outcomes.
Topics: Adult; Collagen; Corneal Stroma; Cross-Linking Reagents; Drug Combinations; Female; Humans; Keratoconus; Male; Ophthalmic Solutions; Photochemotherapy; Photosensitizing Agents; Polyethylene Glycols; Prospective Studies; Radiotherapy Dosage; Riboflavin; Treatment Outcome; Ultraviolet Rays; Visual Acuity; Vitamin E; Young Adult | 2016 |
Emulsification by vitamin E TPGS or Quillaja extract enhanced absorption of berberine without affecting its metabolism in humans.
Topics: Berberine; Cross-Over Studies; Female; Humans; Male; Plant Extracts; Powders; Quillaja; Tandem Mass Spectrometry; Vitamin E | 2022 |
532 other study(ies) available for tocophersolan and d-alpha tocopherol
| Article | Year |
|---|---|
Bioavailability of vitamin E compounds in lambs.
Topics: Absorption; Administration, Oral; alpha-Tocopherol; Animals; Biological Availability; Male; Nicotinic Acids; Polyethylene Glycols; Random Allocation; Sheep; Tocopherols; Vitamin E | 1992 |
d-Alpha-tocopheryl polyethylene glycol-1000 succinate enhances the absorption of vitamin D in chronic cholestatic liver disease of infancy and childhood.
Topics: Adult; Alagille Syndrome; Biliary Atresia; Child; Child, Preschool; Cholestasis; Cholestasis, Intrahepatic; Chronic Disease; Female; Humans; Infant; Intestinal Absorption; Male; Micelles; Polyethylene Glycols; Vitamin D; Vitamin E | 1992 |
Plasma alpha-tocopherol profiles in sheep after oral administration of dl-alpha-tocopheryl acetate and d-alpha-tocopheryl polyethylene glycol-1000 succinate.
Topics: Administration, Oral; alpha-Tocopherol; Animals; Biological Availability; Male; Polyethylene Glycols; Random Allocation; Sheep; Tocopherols; Vitamin E | 1991 |
Reactive oxygen species and non-peroxidative mechanisms of cocaine-induced cytotoxicity in rat hepatocyte cultures.
Topics: Animals; Cell Survival; Cells, Cultured; Cocaine; Deferoxamine; Drug Interactions; Glutathione; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Male; Maleates; Oxygen; Polyethylene Glycols; Rats; Rats, Inbred Strains; Vitamin E | 1991 |
Plasma vitamin E response in two black rhinoceroses following dietary supplementation.
Topics: Animals; Male; Perissodactyla; Polyethylene Glycols; Vitamin E | 1991 |
Comparative evaluation of the antioxidant activity of alpha-tocopherol, alpha-tocopherol polyethylene glycol 1000 succinate and alpha-tocopherol succinate in isolated hepatocytes and liver microsomal suspensions.
Topics: Animals; Antioxidants; Lipid Peroxidation; Liver; Microsomes, Liver; Polyethylene Glycols; Rats; Rats, Inbred Strains; Time Factors; Tocopherols; Vitamin E | 1990 |
Vitamin E deficiency neuropathy in children with fat malabsorption. Studies in cystic fibrosis and chronic cholestasis.
Topics: Cholestasis; Cystic Fibrosis; Humans; Infant; Malabsorption Syndromes; Neuromuscular Diseases; Polyethylene Glycols; Prospective Studies; Vitamin E; Vitamin E Deficiency | 1989 |
Uptake of intact TPGS (d-alpha-tocopheryl polyethylene glycol 1000 succinate) a water-miscible form of vitamin E by human cells in vitro.
Topics: Carbon Radioisotopes; Cell Line; Cholestasis; Erythrocytes; Fibroblasts; Humans; Hydrolysis; Intestinal Mucosa; Kinetics; Polyethylene Glycols; Solubility; Temperature; Tocopherols; Vitamin E; Water | 1988 |
Treatment of vitamin E deficiency during chronic childhood cholestasis with oral d-alpha-tocopheryl polyethylene glycol-1000 succinate.
Topics: Administration, Oral; Child; Cholestasis; Chronic Disease; Female; Humans; Intestinal Absorption; Male; Polyethylene Glycols; Vitamin E; Vitamin E Deficiency | 1987 |
Tocopheryl polyethylene glycol 1000 succinate therapy for vitamin E deficiency during chronic childhood cholestasis: neurologic outcome.
Topics: Child, Preschool; Cholestasis; Chronic Disease; Female; Humans; Infant; Male; Nervous System Diseases; Polyethylene Glycols; Vitamin E; Vitamin E Deficiency | 1987 |
Effects of vitamin E on fibroblast fibronectin.
Topics: Cells, Cultured; Fibroblasts; Fibronectins; Humans; Polyethylene Glycols; Vitamin E | 1985 |
Efficacy of water-soluble vitamin E in the treatment of vitamin E malabsorption in short-bowel syndrome.
Topics: Aged; Humans; Intestinal Absorption; Male; Polyethylene Glycols; Short Bowel Syndrome; Solubility; Vitamin E | 1994 |
Serum total cholesterol, high-density lipoprotein-cholesterol and triglyceride concentrations in lambs following supplementation with various forms of tocopherol.
Topics: alpha-Tocopherol; Animals; Cholesterol; Cholesterol, HDL; Female; Nicotinic Acids; Polyethylene Glycols; Sheep; Tocopherols; Triglycerides; Vitamin E | 1993 |
Research note: vitamin E status of turkey poults as influenced by different dietary vitamin E sources, a bile salt, and an antioxidant.
Topics: alpha-Tocopherol; Animals; Antioxidants; Bile Acids and Salts; Diet; Liver; Male; Nutritional Status; Polyethylene Glycols; Tocopherols; Turkeys; Vitamin E | 1993 |
Use of water-soluble liquid vitamin E to enhance cyclosporine absorption in children after liver transplant.
Topics: Antilymphocyte Serum; Bilirubin; Child; Cyclosporine; Graft Survival; Humans; Intestinal Absorption; Liver Transplantation; Muromonab-CD3; Pilot Projects; Polyethylene Glycols; Retrospective Studies; Vitamin E | 1993 |
Treatment of cholestatic children with water-soluble vitamin E (alpha-tocopheryl polyethylene glycol succinate): effects on serum vitamin E, lipid peroxides, and polyunsaturated fatty acids.
Topics: Child, Preschool; Cholestasis; Fatty Acids; Humans; Infant; Lipid Peroxidation; Phospholipids; Polyethylene Glycols; Solubility; Thiobarbituric Acid Reactive Substances; Vitamin E; Water | 1997 |
Inhibition of P-glycoprotein by D-alpha-tocopheryl polyethylene glycol 1000 succinate (TPGS).
Topics: 3T3 Cells; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Survival; Coloring Agents; Cyclosporine; Fluorouracil; Immunosuppressive Agents; Mice; Micelles; Paclitaxel; Polyethylene Glycols; Rhodamine 123; Vinblastine; Vitamin E | 1999 |
Vitamin E-TPGS increases absorption flux of an HIV protease inhibitor by enhancing its solubility and permeability.
Topics: Algorithms; Animals; Biological Availability; Caco-2 Cells; Calcium Channel Blockers; Carbamates; Cell Membrane Permeability; Chromatography, High Pressure Liquid; Dogs; Furans; HIV Protease Inhibitors; Humans; Permeability; Polyethylene Glycols; Solubility; Stimulation, Chemical; Sulfonamides; Verapamil; Vitamin E | 1999 |
Influence of vitamin E TPGS on the properties of hydrophilic films produced by hot-melt extrusion.
Topics: Administration, Cutaneous; Cellulose; Drug Delivery Systems; Polyethylene Glycols; Temperature; Tensile Strength; Vitamin E | 2000 |
Peppermint oil enhances cyclosporine oral bioavailability in rats: comparison with D-alpha-tocopheryl poly(ethylene glycol 1000) succinate (TPGS) and ketoconazole.
Topics: Administration, Oral; Animals; Antiemetics; Antifungal Agents; Biological Availability; Cyclosporine; Drug Synergism; Humans; Immunosuppressive Agents; Ketoconazole; Male; Mentha piperita; Microsomes, Liver; Plant Oils; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Vitamin E | 2002 |
Possible role of the vitamin E solubilizer in topical diclofenac on matrix metalloproteinase expression in corneal melting: an analysis of postoperative keratolysis.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Cornea; Corneal Diseases; Diclofenac; Female; Humans; In Situ Hybridization; Keratoplasty, Penetrating; Lasers, Excimer; Lens Implantation, Intraocular; Male; Matrix Metalloproteinases; Middle Aged; Photorefractive Keratectomy; Postoperative Complications; Refractive Surgical Procedures; Retrospective Studies; Vitamin E | 2002 |
Vitamin E TPGS used as emulsifier in the solvent evaporation/extraction technique for fabrication of polymeric nanospheres for controlled release of paclitaxel (Taxol).
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Delayed-Action Preparations; Excipients; Microspheres; Nanotechnology; Paclitaxel; Polyethylene Glycols; Polymers; Solvents; Vitamin E | 2002 |
Effects of nonionic surfactants on membrane transporters in Caco-2 cell monolayers.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Cadherins; Carrier Proteins; Cell Membrane Permeability; Dipeptides; Glycerol; Humans; Membrane Fluidity; Membrane Transport Modulators; Membrane Transport Proteins; Monocarboxylic Acid Transporters; Polyethylene Glycols; Polysorbates; Protein Kinase C; Rhodamine 123; Surface-Active Agents; Vitamin E | 2002 |
Sirolimus oral absorption in rats is increased by ketoconazole but is not affected by D-alpha-tocopheryl poly(ethylene glycol 1000) succinate.
Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line; Humans; Intestinal Absorption; Ketoconazole; Kinetics; Male; Metabolic Clearance Rate; Rats; Rats, Sprague-Dawley; Sirolimus; Tumor Cells, Cultured; Vitamin E | 2002 |
Improvement of the bioavailability of colchicine in rats by co-administration of D-alpha-tocopherol polyethylene glycol 1000 succinate and a polyethoxylated derivative of 12-hydroxy-stearic acid.
Topics: alpha-Tocopherol; Animals; Antioxidants; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Chromatography, High Pressure Liquid; Colchicine; Cytochrome P-450 Enzyme System; Intestinal Absorption; Intestinal Mucosa; Intestines; Male; Polyethylene Glycols; Rats; Rats, Wistar; Solubility; Stearic Acids; Stimulation, Chemical; Succinates; Surface-Active Agents; Vitamin E | 2002 |
Enhanced intestinal absorption of vancomycin with Labrasol and D-alpha-tocopheryl PEG 1000 succinate in rats.
Topics: Animals; Area Under Curve; Emulsions; Glycerides; Intestinal Absorption; Male; Organic Chemicals; Polyethylene Glycols; Rats; Rats, Wistar; Vancomycin; Vitamin E | 2003 |
A novel controlled release formulation for the anticancer drug paclitaxel (Taxol): PLGA nanoparticles containing vitamin E TPGS.
Topics: Antineoplastic Agents, Phytogenic; Chemistry, Pharmaceutical; Delayed-Action Preparations; Lactic Acid; Nanotechnology; Paclitaxel; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Vitamin E | 2003 |
Physicochemical characterization of solid dispersion of furosemide with TPGS.
Topics: Chemical Phenomena; Chemistry, Physical; Furosemide; Polyethylene Glycols; Solubility; Vitamin E | 2003 |
Influence of micelle solubilization by tocopheryl polyethylene glycol succinate (TPGS) on solubility enhancement and percutaneous penetration of estradiol.
Topics: Administration, Cutaneous; Animals; Diffusion Chambers, Culture; Dose-Response Relationship, Drug; Estradiol; Mice; Mice, Nude; Micelles; Skin Absorption; Solubility; Vitamin E | 2003 |
PLGA/TPGS nanoparticles for controlled release of paclitaxel: effects of the emulsifier and drug loading ratio.
Topics: Delayed-Action Preparations; Drug Compounding; Emulsifying Agents; Lactic Acid; Nanotechnology; Paclitaxel; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Vitamin E | 2003 |
Solid dispersion of carbamazepine in PVP K30 by conventional solvent evaporation and supercritical methods.
Topics: Calorimetry, Differential Scanning; Carbamazepine; Chemistry, Pharmaceutical; Chromatography, Supercritical Fluid; Polyethylene Glycols; Povidone; Solubility; Solvents; Spectroscopy, Fourier Transform Infrared; Temperature; Vitamin E; X-Ray Diffraction | 2004 |
Delayed onset of ataxia in a patient with short bowel syndrome: a case of vitamin E deficiency.
Topics: Ataxia; Crohn Disease; Humans; Magnesium; Magnesium Deficiency; Male; Middle Aged; Polyethylene Glycols; Short Bowel Syndrome; Vitamin E; Vitamin E Deficiency | 2004 |
Physical characterizations of microemulsion systems using tocopheryl polyethylene glycol 1000 succinate (TPGS) as a surfactant for the oral delivery of protein drugs.
Topics: Chemical Phenomena; Chemistry, Physical; Drug Carriers; Emulsions; Molecular Weight; Oils; Polyethylene Glycols; Polysorbates; Proteins; Surface-Active Agents; Triglycerides; Vitamin E | 2005 |
Novel powder formulations for controlled delivery of poorly soluble anticancer drug: application and investigation of TPGS and PEG in spray-dried particulate system.
Topics: Antineoplastic Agents; Calorimetry, Differential Scanning; Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Chromatography, High Pressure Liquid; Drug Compounding; Excipients; Lactic Acid; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Powders; Solubility; Surface Properties; Vitamin E | 2005 |
Effect of vitamin E TPGS on immune response to nasally delivered diphtheria toxoid loaded poly(caprolactone) microparticles.
Topics: Administration, Intranasal; Animals; Antioxidants; Chemistry, Pharmaceutical; Desiccation; Diphtheria Toxoid; Emulsions; Immunoglobulin G; Mice; Mice, Inbred BALB C; Microscopy, Electron, Scanning; Microspheres; Particle Size; Polyesters; Polyethylene Glycols; Vitamin E | 2005 |
Excipient effects on gastrointestinal transit and drug absorption in beagle dogs.
Topics: Ampicillin; Animals; Antipyrine; Biological Availability; Dogs; Excipients; Female; Gastric Emptying; Glycerides; Intestinal Absorption; Male; Organic Chemicals; Polyethylene Glycols; Propylene Glycol; Succinates; Vitamin E | 2005 |
Nanoparticles of poly(lactide)/vitamin E TPGS copolymer for cancer chemotherapy: synthesis, formulation, characterization and in vitro drug release.
Topics: Antineoplastic Agents, Phytogenic; Drug Carriers; Drug Therapy; Humans; Lactic Acid; Molecular Structure; Molecular Weight; Nanostructures; Neoplasms; Paclitaxel; Particle Size; Polyesters; Polyethylene Glycols; Polymers; Surface Properties; Vitamin E | 2006 |
Enhanced anticancer efficacy of alpha-tocopheryl succinate by conjugation with polyethylene glycol.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Carriers; Drug Evaluation, Preclinical; Female; Flow Cytometry; Humans; Immunoblotting; Injections, Subcutaneous; Kinetics; Mice; Mice, Nude; Molecular Structure; Neoplasm Transplantation; Polyethylene Glycols; Reactive Oxygen Species; Transplantation, Heterologous; Vitamin E; Xenograft Model Antitumor Assays | 2005 |
Mixed micelles made of poly(ethylene glycol)-phosphatidylethanolamine conjugate and d-alpha-tocopheryl polyethylene glycol 1000 succinate as pharmaceutical nanocarriers for camptothecin.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Stability; Humans; Micelles; Nanostructures; Particle Size; Polyethylene Glycols; Solubility; Vitamin E | 2005 |
Simultaneous effects of tocopheryl polyethylene glycol succinate (TPGS) on local hair growth promotion and systemic absorption of topically applied minoxidil in a mouse model.
Topics: Administration, Topical; Alopecia; Animals; Disease Models, Animal; Drug Carriers; Hair; Male; Mice; Mice, Inbred C57BL; Minoxidil; Polyethylene Glycols; Skin Absorption; Succinates; Sulfotransferases; Time Factors; Vitamin E | 2005 |
In vitro and in vivo studies on vitamin E TPGS-emulsified poly(D,L-lactic-co-glycolic acid) nanoparticles for paclitaxel formulation.
Topics: Antineoplastic Agents, Phytogenic; Area Under Curve; Drug Carriers; Drug Delivery Systems; Emulsifying Agents; Glycerol; Humans; Lactic Acid; Nanostructures; Paclitaxel; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Surface-Active Agents; Vitamin E | 2006 |
Influence of vitamin E TPGS poly(ethylene glycol) chain length on apical efflux transporters in Caco-2 cell monolayers.
Topics: Analysis of Variance; Biological Transport; Caco-2 Cells; Cell Survival; Dose-Response Relationship, Drug; Humans; Molecular Structure; Polyethylene Glycols; Quantitative Structure-Activity Relationship; Rhodamine 123; Vitamin E | 2006 |
Application of TPGS in polymeric nanoparticulate drug delivery system.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Antineoplastic Agents, Phytogenic; Cell Membrane; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Kinetics; Nanotechnology; Paclitaxel; Polyethylene Glycols; Polymers; Surface Properties; Vitamin E | 2006 |
Effect of tocopheryl polyethylene glycol succinate on the percutaneous penetration of minoxidil from water/ethanol/polyethylene glycol 400 solutions.
Topics: Administration, Cutaneous; Algorithms; Animals; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Carriers; Ethanol; Mice; Mice, Inbred BALB C; Mice, Nude; Minoxidil; Polyethylene Glycols; Skin Absorption; Solubility; Solutions; Surface-Active Agents; Vasodilator Agents; Vitamin E; Water | 2006 |
Impact of formulation excipients on human intestinal transit.
Topics: Adult; Caprylates; Chemistry, Pharmaceutical; Excipients; Gastric Emptying; Gastrointestinal Transit; Glycerides; Humans; Male; Middle Aged; Polyethylene Glycols; Propylene Glycol; Vitamin E | 2006 |
A comparison of intestinal lymphatic transport and systemic bioavailability of saquinavir from three lipid-based formulations in the anaesthetised rat model.
Topics: Anesthesia; Animals; Biological Availability; Biological Transport; Excipients; HIV Protease Inhibitors; Intestinal Absorption; Intestinal Mucosa; Lymph; Male; Micelles; Oleic Acid; Polyethylene Glycols; Rats; Rats, Wistar; Saquinavir; Succinates; Triglycerides; Vitamin E | 2006 |
Self-assembled nanoparticles of poly(lactide)--Vitamin E TPGS copolymers for oral chemotherapy.
Topics: Administration, Oral; Antineoplastic Agents, Phytogenic; Caco-2 Cells; Calorimetry, Differential Scanning; Cell Survival; Chemistry, Pharmaceutical; Humans; Hydrogen-Ion Concentration; Nanoparticles; Paclitaxel; Particle Size; Polyesters; Polyethylene Glycols; Solubility; Vitamin E | 2006 |
Etodolac-liquid-filled dispersion into hard gelatin capsules: an approach to improve dissolution and stability of etodolac formulation.
Topics: Calorimetry, Differential Scanning; Capsules; Crystallization; Drug Carriers; Drug Stability; Etodolac; Gelatin; Humidity; Polyethylene Glycols; Solubility; Spectroscopy, Fourier Transform Infrared; Temperature; Vitamin E | 2006 |
Folate-decorated poly(lactide-co-glycolide)-vitamin E TPGS nanoparticles for targeted drug delivery.
Topics: Animals; Breast Neoplasms; Capsules; Cell Line, Tumor; Cell Survival; Coated Materials, Biocompatible; Diffusion; Drug Carriers; Folic Acid; Lactic Acid; Materials Testing; Mice; Nanostructures; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Vitamin E | 2007 |
Microemulsions as topical delivery vehicles for the anti-melanoma prodrug, temozolomide hexyl ester (TMZA-HE).
Topics: Administration, Cutaneous; Animals; Antineoplastic Agents, Alkylating; Dacarbazine; Detergents; Drug Carriers; Drug Delivery Systems; Emulsions; Esters; In Vitro Techniques; Melanoma; Mice; Mice, Hairless; Myristates; Oleic Acid; Permeability; Pharmaceutical Vehicles; Polyethylene Glycols; Prodrugs; Rats; Skin Absorption; Skin Neoplasms; Solubility; Temozolomide; Vitamin E | 2007 |
Potential use of cholecalciferol polyethylene glycol succinate as a novel pharmaceutical additive.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biocompatible Materials; Caco-2 Cells; Chemistry, Pharmaceutical; Cholecalciferol; Drug Delivery Systems; Humans; Magnetic Resonance Spectroscopy; Micelles; Nanoparticles; Particle Size; Polyethylene Glycols; Polymers; Rhodamines; Spectroscopy, Fourier Transform Infrared; Succinates; Vitamin E | 2008 |
d-alpha-Tocopheryl polyethylene glycol 1000 succinate (TPGS) modified poly(l-lactide) (PLLA) films for localized delivery of paclitaxel.
Topics: Calorimetry, Differential Scanning; Drug Delivery Systems; Paclitaxel; Polyesters; Polyethylene Glycols; Solubility; Tensile Strength; Vitamin E | 2008 |
An investigation of the thermodynamic miscibility between VeTPGS and polymers.
Topics: Calorimetry, Differential Scanning; Polyethylene Glycols; Polymethyl Methacrylate; Solubility; Thermodynamics; Vitamin E; X-Ray Diffraction | 2008 |
Formulation and characterization of ternary solid dispersions made up of Itraconazole and two excipients, TPGS 1000 and PVPVA 64, that were selected based on a supersaturation screening study.
Topics: Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Crystallization; Dosage Forms; Drug Compounding; Drug Delivery Systems; Drug Evaluation, Preclinical; Excipients; Gas Chromatography-Mass Spectrometry; Itraconazole; Polyethylene Glycols; Povidone; Pyrrolidines; Solubility; Temperature; Vinyl Compounds; Vitamin E; X-Ray Diffraction | 2008 |
Combination of Pluronic/Vitamin E TPGS as a potential inhibitor of drug precipitation.
Topics: Body Fluids; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Stability; Excipients; Hydrogen-Ion Concentration; Indicators and Reagents; Poloxamer; Polyethylene Glycols; Surface-Active Agents; Vitamin E; X-Ray Diffraction | 2008 |
Preparation and characterization of Pluronic/TPGS mixed micelles for solubilization of camptothecin.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Camptothecin; Cell Line, Tumor; Cell Survival; Colorimetry; Drug Screening Assays, Antitumor; Female; Humans; Micelles; Molecular Structure; Poloxamer; Polyethylene Glycols; Solubility; Vitamin E | 2008 |
Targeted delivery of paclitaxel using folate-decorated poly(lactide)-vitamin E TPGS nanoparticles.
Topics: Antineoplastic Agents, Phytogenic; Brain Neoplasms; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Drug Delivery Systems; Female; Folic Acid; Humans; Molecular Structure; Nanoparticles; Nanotechnology; Paclitaxel; Particle Size; Polyesters; Polyethylene Glycols; Spectrum Analysis; Vitamin E | 2008 |
Quercetin in lyotropic liquid crystalline formulations: physical, chemical and functional stability.
Topics: Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Dosage Forms; Drug Compounding; Drug Stability; Emulsifying Agents; Free Radical Scavengers; Humidity; Liquid Crystals; Myristates; Polyethylene Glycols; Propylene Glycol; Quercetin; Technology, Pharmaceutical; Temperature; Time Factors; Vitamin E | 2008 |
Enhanced oral bioavailability of paclitaxel by D-alpha-tocopheryl polyethylene glycol 400 succinate in mice.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Biological Availability; Caco-2 Cells; Ethanol; Glycerol; Humans; Injections, Intravenous; Male; Mice; Mice, Inbred BALB C; Microsomes, Liver; Paclitaxel; Permeability; Polyethylene Glycols; Rhodamine 123; Solvents; Steroid Hydroxylases; Vitamin E | 2008 |
Formulation of fast disintegrating tablets of ternary solid dispersions consisting of TPGS 1000 and HPMC 2910 or PVPVA 64 to improve the dissolution of the anti-HIV drug UC 781.
Topics: Anilides; Anti-HIV Agents; Chemistry, Pharmaceutical; Drug Carriers; Drug Compounding; Furans; Hypromellose Derivatives; Kinetics; Methylcellulose; Models, Chemical; Polyethylene Glycols; Povidone; Pyrrolidines; Solubility; Tablets; Technology, Pharmaceutical; Thermodynamics; Thioamides; Transition Temperature; Vinyl Compounds; Vitamin E | 2008 |
Doxorubicin conjugated to D-alpha-tocopheryl polyethylene glycol 1000 succinate (TPGS): conjugation chemistry, characterization, in vitro and in vivo evaluation.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Doxorubicin; Drug Carriers; Female; Humans; Male; Molecular Structure; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Tissue Distribution; Vitamin E | 2008 |
Ciclosporin-loaded poly(lactide) microparticles: effect of TPGS.
Topics: Cyclosporine; Drug Carriers; Lactic Acid; Microspheres; Plasticizers; Polyesters; Polyethylene Glycols; Polymers; Solvents; Vitamin E | 2009 |
Free flowing solid dispersions of the anti-HIV drug UC 781 with Poloxamer 407 and a maximum amount of TPGS 1000: investigating the relationship between physicochemical characteristics and dissolution behaviour.
Topics: Algorithms; Anilides; Anti-HIV Agents; Calorimetry, Differential Scanning; Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Chromatography, High Pressure Liquid; Desiccation; Drug Carriers; Drug Compounding; Excipients; Furans; Hydrolysis; Poloxamer; Polyethylene Glycols; Solubility; Thioamides; Vitamin E; X-Ray Diffraction | 2008 |
Dissolution enhancement of the anti-HIV drug UC 781 by formulation in a ternary solid dispersion with TPGS 1000 and Eudragit E100.
Topics: Acrylates; Anilides; Anti-HIV Agents; Chemistry, Pharmaceutical; Drug Carriers; Furans; Kinetics; Polyethylene Glycols; Polymers; Powders; Solubility; Surface-Active Agents; Technology, Pharmaceutical; Thioamides; Transition Temperature; Vitamin E | 2008 |
Formulation, characterization, and in vitro evaluation of quantum dots loaded in poly(lactide)-vitamin E TPGS nanoparticles for cellular and molecular imaging.
Topics: Cell Line, Tumor; Cells; Humans; Image Processing, Computer-Assisted; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanoparticles; Polyesters; Polyethylene Glycols; Quantum Dots; Spectroscopy, Fourier Transform Infrared; Staining and Labeling; Vitamin E | 2008 |
Addition of TPGS to folate-conjugated polymer micelles for selective tumor targeting.
Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Cell Line; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Delivery Systems; Folate Receptors, GPI-Anchored; Folic Acid; Gene Expression Regulation, Neoplastic; Humans; Lactic Acid; Micelles; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Receptors, Cell Surface; Rhodamines; Vitamin E | 2009 |
Targeting and imaging cancer cells by folate-decorated, quantum dots (QDs)- loaded nanoparticles of biodegradable polymers.
Topics: Animals; Biocompatible Materials; Cell Death; Cell Line, Tumor; Cell Survival; Folic Acid; Humans; Mice; Microscopy, Confocal; Microscopy, Electron; Nanoparticles; Neoplasms; NIH 3T3 Cells; Particle Size; Polyethylene Glycols; Quantum Dots; Spectrum Analysis; Static Electricity; Succinates; Surface Properties; Vitamin E | 2009 |
Inhibiting efflux with novel non-ionic surfactants: Rational design based on vitamin E TPGS.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Biological Transport; Caco-2 Cells; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Carriers; Humans; Male; Mass Spectrometry; Polyethylene Glycols; Raloxifene Hydrochloride; Rats; Rats, Inbred Strains; Rhodamine 123; Surface-Active Agents; Vitamin E | 2009 |
Investigation of the micellar properties of the tocopheryl polyethylene glycol succinate surfactants TPGS 400 and TPGS 1000 by steady state fluorometry.
Topics: Fluorometry; Micelles; Octoxynol; Polyethylene Glycols; Pyrenes; Surface-Active Agents; Viscosity; Vitamin E | 2009 |
Preparation of sustained release microparticles with improved initial release property.
Topics: Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Octreotide; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Surface Properties; Vitamin E | 2009 |
Activity of SQ641, a capuramycin analog, in a murine model of tuberculosis.
Topics: Aminoglycosides; Animals; Antitubercular Agents; Disease Models, Animal; Female; Mice; Mice, Inbred C57BL; Mycobacterium tuberculosis; Solubility; Tuberculosis; Vitamin E | 2009 |
Liposomal formulation of alpha-tocopheryl maleamide: in vitro and in vivo toxicological profile and anticancer effect against spontaneous breast carcinomas in mice.
Topics: alpha-Tocopherol; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Chemistry, Pharmaceutical; Female; Humans; Liposomes; Maleimides; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Polyethylene Glycols; Vitamin E | 2009 |
Preparation and properties of hydroxycamptothecin-loaded nanoparticles made of amphiphilic copolymer and normal polymer.
Topics: Camptothecin; Cell Line, Tumor; Drug Carriers; Humans; Micelles; Nanoparticles; Polyethylene Glycols; Polymers; Vitamin E | 2009 |
Itraconazole/TPGS/Aerosil200 solid dispersions: characterization, physical stability and in vivo performance.
Topics: Animals; Chemistry, Pharmaceutical; Crystallization; Drug Carriers; Drug Stability; Itraconazole; Male; Polyethylene Glycols; Powders; Rats; Rats, Wistar; Silicon Dioxide; Vitamin E; X-Ray Diffraction | 2009 |
Correlation of the penetration enhancement with the influence of an alcohol/tocopheryl polyethylene glycol succinate (TPGS) cosolvent system on the molecular structure of the stratum corneum of nude mouse skin as examined by microscopic FTIR/DSC.
Topics: Animals; Calorimetry, Differential Scanning; Estradiol; Ethanol; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Polyethylene Glycols; Skin; Skin Absorption; Spectroscopy, Fourier Transform Infrared; Vitamin E | 2009 |
Particle size analysis of nanocrystals: improved analysis method.
Topics: Chemistry Techniques, Analytical; Cyclosporine; Drug Stability; Excipients; Light; Microscopy; Nanoparticles; Particle Size; Poloxamer; Polyethylene Glycols; Polysorbates; Refractometry; Rutin; Scattering, Radiation; Scattering, Small Angle; Sodium Dodecyl Sulfate; Solubility; Temperature; Vitamin E | 2010 |
Tabletability assessment of conventional formulations containing Vitamin E tocopheryl polyethylene glycol succinate.
Topics: Biological Availability; Cellulose; Chemistry, Pharmaceutical; Excipients; Polyethylene Glycols; Solubility; Tablets; Temperature; Tensile Strength; Transition Temperature; Vitamin E | 2010 |
Vitamin E TPGS P-glycoprotein inhibition mechanism: influence on conformational flexibility, intracellular ATP levels, and role of time and site of access.
Topics: Adenosine Triphosphate; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Humans; Polyethylene Glycols; Protein Conformation; Vitamin E | 2010 |
Doxorubicin conjugated to D-alpha-tocopheryl polyethylene glycol succinate and folic acid as a prodrug for targeted chemotherapy.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Doxorubicin; Drug Carriers; Folic Acid; Humans; Materials Testing; Molecular Structure; Polyethylene Glycols; Prodrugs; Random Allocation; Rats; Rats, Sprague-Dawley; Tissue Distribution; Vitamin E | 2010 |
Design and evaluation of micellar nanocarriers for 17-allyamino-17-demethoxygeldanamycin (17-AAG).
Topics: Antineoplastic Agents; Benzoquinones; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Drug Carriers; Drug Design; Drug Evaluation, Preclinical; Drug Stability; Drug Storage; Humans; Lactams, Macrocyclic; Magnetic Resonance Spectroscopy; Micelles; Nanoparticles; Particle Size; Phosphatidylethanolamines; Polyethylene Glycols; Solubility; Vitamin E | 2010 |
Multifunctional nanoparticles of biodegradable copolymer blend for cancer diagnosis and treatment.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Membrane Permeability; Cell Survival; Docetaxel; Female; Humans; Lactic Acid; Mice; Nanoparticles; NIH 3T3 Cells; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Quantum Dots; Taxoids; Vitamin E | 2010 |
Approaches to improve the stability of the antiviral agent UC781 in aqueous solutions.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Anilides; Antioxidants; Antiviral Agents; Ascorbic Acid; beta-Cyclodextrins; Chemistry, Pharmaceutical; Dimethyl Sulfoxide; Drug Compounding; Drug Stability; Edetic Acid; Excipients; Fumarates; Furans; Glutathione; Hot Temperature; Models, Chemical; Oxidation-Reduction; Polyethylene Glycols; Polysorbates; Solubility; Sulfites; Technology, Pharmaceutical; Thioamides; Time Factors; Vitamin E | 2010 |
Preparation, characterization, pharmacokinetics, and tissue distribution of curcumin nanosuspension with TPGS as stabilizer.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Chemical Phenomena; Chemistry, Pharmaceutical; Curcumin; Drug Carriers; Drug Stability; Excipients; Infusions, Intravenous; Mice; Nanoparticles; Nanospheres; Particle Size; Polyethylene Glycols; Powders; Rabbits; Solubility; Suspensions; Tissue Distribution; Vitamin E | 2010 |
Enhanced oral bioavailability of paclitaxel formulated in vitamin E-TPGS emulsified nanoparticles of biodegradable polymers: in vitro and in vivo studies.
Topics: Absorbable Implants; Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Biological Availability; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Carriers; Electrochemistry; Excipients; Humans; Lactic Acid; Light; Microscopy, Electron, Scanning; Nanoparticles; Paclitaxel; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Sprague-Dawley; Scattering, Radiation; Vitamin E | 2010 |
Validation of a differential in situ perfusion method with mesenteric blood sampling in rats for intestinal drug interaction profiling.
Topics: Adrenergic beta-Antagonists; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carbamates; Drug Interactions; Furans; Intestinal Absorption; Ketoconazole; Male; Perfusion; Polyethylene Glycols; Rats; Rats, Wistar; Splanchnic Circulation; Sulfonamides; Verapamil; Vitamin E | 2010 |
Poly(L-lactide)-vitamin E TPGS nanoparticles enhanced the cytotoxicity of doxorubicin in drug-resistant MCF-7 breast cancer cells.
Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Catalysis; Cell Culture Techniques; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Carriers; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Microscopy, Electron, Transmission; Nanoparticles; Particle Size; Polyethylene Glycols; Solubility; Succinates; Surface Properties; Vitamin E | 2010 |
Solubility increases associated with crystalline drug nanoparticles: methodologies and significance.
Topics: Acetamides; Acetophenones; Chemistry, Pharmaceutical; Crystallization; Drug Stability; Excipients; Itraconazole; Light; Micelles; Nanoparticles; Naproxen; Nephelometry and Turbidimetry; Particle Size; Phenytoin; Polyethylene Glycols; Scattering, Radiation; Solubility; Suspensions; Vitamin E | 2010 |
In vitro evaluation of liposomes containing bio-enhancers for the oral delivery of macromolecules.
Topics: Administration, Oral; Amines; Caco-2 Cells; Cholesterol; Cholic Acids; Dextrans; Drug Carriers; Drug Delivery Systems; Fluorescein-5-isothiocyanate; Humans; Liposomes; Macromolecular Substances; Phosphatidylcholines; Polyethylene Glycols; Sarcosine; Vitamin E | 2010 |
The biocompatibility and separation performance of antioxidative polysulfone/vitamin E TPGS composite hollow fiber membranes.
Topics: Animals; Biocompatible Materials; Cell Proliferation; Hemolysis; Membranes, Artificial; Mice; Microscopy, Confocal; Microscopy, Electron, Scanning; NIH 3T3 Cells; Platelet Aggregation; Polyethylene Glycols; Polymers; Renal Dialysis; Spectroscopy, Fourier Transform Infrared; Sulfones; Thermogravimetry; Ultrafiltration; Vitamin E | 2011 |
Characterisation of fenofibrate dissolution delivered by a self-microemulsifying drug-delivery system.
Topics: Biological Availability; Drug Delivery Systems; Emulsifying Agents; Excipients; Fenofibrate; Hypolipidemic Agents; Polyethylene Glycols; Polysorbates; Propylene Glycol; Sodium Dodecyl Sulfate; Solubility; Triglycerides; Viscosity; Vitamin E | 2010 |
Folate-decorated hybrid polymeric nanoparticles for chemically and physically combined paclitaxel loading and targeted delivery.
Topics: Animals; Antineoplastic Agents, Phytogenic; Drug Delivery Systems; Drug Screening Assays, Antitumor; Folic Acid; HeLa Cells; Humans; Mice; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Nanoparticles; NIH 3T3 Cells; Paclitaxel; Particle Size; Polyesters; Polyethylene Glycols; Vitamin E | 2011 |
Technetium-99m-labeled poly(DL-lactide-co-glycolide) nanoparticles as an alternative for sentinel lymph node imaging.
Topics: Animal Structures; Animals; Cryoprotective Agents; Female; Freeze Drying; Isotope Labeling; Lactic Acid; Lymph Nodes; Microscopy, Atomic Force; Nanoparticles; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Radionuclide Imaging; Rats; Rats, Wistar; Sentinel Lymph Node Biopsy; Surface-Active Agents; Technetium; Tissue Distribution; Vitamin E | 2010 |
Nanosuspension for improving the bioavailability of a poorly soluble drug and screening of stabilizing agents to inhibit crystal growth.
Topics: Animals; Benzodiazepinones; Biological Availability; Crystallization; Dogs; Drug Carriers; Drug Stability; Excipients; Hydrophobic and Hydrophilic Interactions; Hypromellose Derivatives; Male; Methylcellulose; Nanoparticles; Particle Size; Phenylurea Compounds; Polyethylene Glycols; Solubility; Suspensions; Vitamin E | 2011 |
Investigating the stability of the nonionic surfactants tocopheryl polyethylene glycol succinate and sucrose laurate by HPLC-MS, DAD, and CAD.
Topics: Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Mass Spectrometry; Polyethylene Glycols; Sucrose; Surface-Active Agents; Temperature; Vitamin E | 2011 |
Formulation of Docetaxel by folic acid-conjugated d-α-tocopheryl polyethylene glycol succinate 2000 (Vitamin E TPGS(2k)) micelles for targeted and synergistic chemotherapy.
Topics: Animals; Cell Line, Tumor; Cell Survival; Docetaxel; Folic Acid; Humans; Mice; Micelles; Microscopy, Confocal; Nanotechnology; NIH 3T3 Cells; Polyethylene Glycols; Polymers; Taxoids; Vitamin E | 2011 |
Effect of D-α-tocopheryl polyethylene glycol 1000 succinate (TPGS) on surfactant monolayers.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Lipid Bilayers; Liposomes; Molecular Structure; Oleic Acid; Oxidation-Reduction; Phosphatidylglycerols; Polyethylene Glycols; Spectrometry, Fluorescence; Surface Properties; Surface-Active Agents; Vitamin E | 2011 |
Characterization of solid dispersions of itraconazole and vitamin E TPGS prepared by microwave technology.
Topics: Calorimetry, Differential Scanning; Crystallization; Dosage Forms; Drug Compounding; Drug Delivery Systems; Itraconazole; Microwaves; Polyethylene Glycols; Spectroscopy, Fourier Transform Infrared; Surface-Active Agents; Vitamin E; X-Ray Diffraction | 2010 |
Reversal of doxorubicin-resistance by multifunctional nanoparticles in MCF-7/ADR cells.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; Cell Survival; Cytoplasmic Granules; Cytosol; Doxorubicin; Drug Carriers; Drug Combinations; Drug Resistance, Neoplasm; Female; Fluoresceins; Fluorescent Dyes; Humans; Lactic Acid; Light; Molecular Structure; Nanoparticles; Particle Size; Photochemotherapy; Photosensitizing Agents; Polyesters; Polyethylene Glycols; Polymers; Porphyrins; Verapamil; Vitamin E | 2011 |
Factors affecting drug encapsulation and stability of lipid-polymer hybrid nanoparticles.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Compounding; Drug Delivery Systems; Drug Stability; Lactic Acid; Levofloxacin; Lipids; Microscopy, Electron, Scanning; Nanoparticles; Ofloxacin; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solubility; Surface-Active Agents; Vitamin E; Water | 2011 |
TPGS-750-M: a second-generation amphiphile for metal-catalyzed cross-couplings in water at room temperature.
Topics: Catalysis; Hydrophobic and Hydrophilic Interactions; Metals; Micelles; Polyethylene Glycols; Succinates; Sulfonamides; Surface-Active Agents; Temperature; Thiadiazoles; Vitamin E; Water | 2011 |
Vitamin E (D-alpha-tocopheryl-co-poly(ethylene glycol) 1000 succinate) micelles-superparamagnetic iron oxide nanoparticles for enhanced thermotherapy and MRI.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Hyperthermia, Induced; Magnetic Resonance Imaging; Mice; Mice, SCID; Micelles; Nanoparticles; Polyethylene Glycols; Vitamin E; Xenograft Model Antitumor Assays | 2011 |
Bioavailability study of berberine and the enhancing effects of TPGS on intestinal absorption in rats.
Topics: Administration, Oral; Animals; Berberine; Biological Availability; Drug Carriers; Drug Synergism; Intestinal Absorption; Male; Polyethylene Glycols; Random Allocation; Rats; Rats, Wistar; Vitamin E | 2011 |
Evaluation of protein stability and in vitro permeation of lyophilized polysaccharides-based microparticles for intranasal protein delivery.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Absorption; Administration, Intranasal; beta-Cyclodextrins; Chitosan; Freeze Drying; Humans; Hypromellose Derivatives; Methylcellulose; Muramidase; Nasal Mucosa; Particle Size; Polyethylene Glycols; Powders; Primary Cell Culture; Protein Stability; Succinates; Vitamin E | 2011 |
Supersaturated dissolution data and their interpretation: the TPGS-carbamazepine model case.
Topics: Anticonvulsants; Carbamazepine; Drug Carriers; Models, Theoretical; Polyethylene Glycols; Solubility; Temperature; Vitamin E | 2011 |
Multi-drug delivery to tumor cells via micellar nanocarriers.
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzoquinones; Cell Line, Tumor; Cell Proliferation; Delayed-Action Preparations; Drug Carriers; Drug Combinations; Drug Delivery Systems; Female; Half-Life; Humans; Lactams, Macrocyclic; Micelles; Nanoparticles; Ovarian Neoplasms; Paclitaxel; Phosphatidylethanolamines; Polyethylene Glycols; Vitamin E | 2011 |
Nanoformulation of D-α-tocopheryl polyethylene glycol 1000 succinate-b-poly(ε-caprolactone-ran-glycolide) diblock copolymer for breast cancer therapy.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Docetaxel; Female; Humans; Magnetic Resonance Spectroscopy; Mice; Mice, SCID; Microscopy, Electron, Scanning; Nanoparticles; Polyesters; Polyethylene Glycols; Polyglycolic Acid; Random Allocation; Taxoids; Vitamin E; Xenograft Model Antitumor Assays | 2011 |
Vitamin E TPGS coated liposomes enhanced cellular uptake and cytotoxicity of docetaxel in brain cancer cells.
Topics: Absorption; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Coumarins; Docetaxel; Glioma; Humans; Liposomes; Microscopy, Atomic Force; Microscopy, Confocal; Microscopy, Electron, Transmission; Particle Size; Polyethylene Glycols; Taxoids; Thiazoles; Vitamin E | 2011 |
Direct quantification of mono- and di-D-α-tocopherol polyethylene glycol 1000 succinate by high performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Drug Stability; Linear Models; Polyethylene Glycols; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Vitamin E | 2011 |
In situ formation of nanocrystals from a self-microemulsifying drug delivery system to enhance oral bioavailability of fenofibrate.
Topics: Administration, Oral; Analysis of Variance; Area Under Curve; Biological Availability; Drug Carriers; Drug Delivery Systems; Emulsions; Fenofibrate; Humans; Nanoparticles; Particle Size; Polyethylene Glycols; Polysorbates; Solubility; Vitamin E | 2011 |
Development and optimization of oil-filled lipid nanoparticles containing docetaxel conjugates designed to control the drug release rate in vitro and in vivo.
Topics: Analysis of Variance; Animals; Area Under Curve; Cell Line, Tumor; Cell Survival; Delayed-Action Preparations; Docetaxel; Drug Carriers; Fatty Acids; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Polyethylene Glycols; Solubility; Taxoids; Triglycerides; Vitamin E | 2011 |
Practical preparation procedures for docetaxel-loaded nanoparticles using polylactic acid-co-glycolic acid.
Topics: Acetates; Centrifugation; Chloroform; Docetaxel; Lactic Acid; Nanocapsules; Nanoparticles; Particle Size; Photoelectron Spectroscopy; Poloxamer; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyvinyl Alcohol; Sonication; Surface Tension; Surface-Active Agents; Taxoids; Vitamin E | 2011 |
Overcoming instability and low solubility of new cytostatic compounds: a comparison of two approaches.
Topics: Antioxidants; beta-Cyclodextrins; Biological Availability; Chemistry, Pharmaceutical; Cytostatic Agents; Drug Stability; Freeze Drying; Hydroxyquinolines; Kinetics; Magnetic Resonance Spectroscopy; Micelles; Particle Size; Photoelectron Spectroscopy; Polyethylene Glycols; Solubility; Surface-Active Agents; Vitamin E; Water | 2012 |
SPANosomes as delivery vehicles for small interfering RNA (siRNA).
Topics: Aromatase; Cell Line, Tumor; Cryoelectron Microscopy; Fatty Acids, Monounsaturated; Flow Cytometry; Gene Knockdown Techniques; Green Fluorescent Proteins; Hexoses; Humans; Liposomes; Microscopy, Electron, Transmission; Nanoparticles; Oligonucleotide Probes; Particle Size; Polyethylene Glycols; Quaternary Ammonium Compounds; RNA, Small Interfering; Surface-Active Agents; Transfection; Vitamin E | 2012 |
Quantitative control of targeting effect of anticancer drugs formulated by ligand-conjugated nanoparticles of biodegradable copolymer blend.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Biocompatible Materials; Biodegradation, Environmental; Cell Line, Tumor; Drug Delivery Systems; Humans; Immunohistochemistry; Lactic Acid; Ligands; Nanoparticles; Nanotechnology; Particle Size; Polyesters; Polyethylene Glycols; Polymers; Surface Properties; Trastuzumab; Vitamin E | 2012 |
Induction of DNA damage and caspase-independent programmed cell death by vitamin E.
Topics: Apoptosis; Caspase 3; Caspases; Cell Line, Tumor; DNA Damage; Drug Screening Assays, Antitumor; Etoposide; Humans; Isomerism; Male; Poly(ADP-ribose) Polymerases; Polyethylene Glycols; Prostatic Neoplasms; Tocotrienols; Vitamin E | 2012 |
Supramolecular micellar nanoaggregates based on a novel chitosan/vitamin E succinate copolymer for paclitaxel selective delivery.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Chitosan; Delayed-Action Preparations; Diffusion; Female; Humans; Micelles; Nanocapsules; Paclitaxel; Polyethylene Glycols; Vitamin E | 2011 |
A comparative study of vitamin E TPGS/HPMC supersaturated system and other solubilizer/polymer combinations to enhance the permeability of a poorly soluble drug through the skin.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Crystallization; Drug Stability; Hypromellose Derivatives; Ibuprofen; In Vitro Techniques; Membranes, Artificial; Methylcellulose; Particle Size; Permeability; Poloxamer; Polyethylene Glycols; Povidone; Propylene Glycol; Skin; Skin Absorption; Solubility; Solvents; Swine; Vitamin E | 2012 |
Theranostic liposomes of TPGS coating for targeted co-delivery of docetaxel and quantum dots.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Survival; Docetaxel; Female; Humans; Liposomes; Polyethylene Glycols; Quantum Dots; Radiation-Sensitizing Agents; Taxoids; Vitamin E | 2012 |
Development of docetaxel-loaded vitamin E TPGS micelles: formulation optimization, effects on brain cancer cells and biodistribution in rats.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Docetaxel; Drug Carriers; Glioma; Humans; Male; Micelles; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Taxoids; Vitamin E | 2012 |
Poloxamer 407/TPGS mixed micelles for delivery of gambogic acid to breast and multidrug-resistant cancer.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Micelles; Nanocapsules; Particle Size; Poloxamer; Polyethylene Glycols; Vitamin E; Xanthones | 2012 |
Mixed micelles of PEG(2000)-DSPE and vitamin-E TPGS for concurrent delivery of paclitaxel and parthenolide: enhanced chemosenstization and antitumor efficacy against non-small cell lung cancer (NSCLC) cell lines.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Drug Carriers; Humans; Inhibitory Concentration 50; Lung Neoplasms; Magnetic Resonance Spectroscopy; Micelles; Paclitaxel; Particle Size; Phosphatidylethanolamines; Polyethylene Glycols; Sesquiterpenes; Vitamin E | 2012 |
Influence of vitamin E tocopherol polyethylene glycol succinate 1000 on intestinal absorption of icariside II.
Topics: Algorithms; Animals; Caco-2 Cells; Chromatography, High Pressure Liquid; Colon; Electric Impedance; Flavonoids; Humans; Ileum; In Vitro Techniques; Intestinal Absorption; Male; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Vitamin E | 2012 |
Solid dispersions of itraconazole for inhalation with enhanced dissolution, solubility and dispersion properties.
Topics: Administration, Inhalation; Aerosols; Antifungal Agents; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Drug Compounding; Excipients; Itraconazole; Mannitol; Particle Size; Polyethylene Glycols; Powders; Solubility; Transition Temperature; Vitamin E; X-Ray Diffraction | 2012 |
Self-nanoemulsifying drug delivery system of cefpodoxime proxetil containing tocopherol polyethylene glycol succinate.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Area Under Curve; Biological Availability; Caprylates; Cefpodoxime Proxetil; Ceftizoxime; Drug Delivery Systems; Drug Stability; Emulsions; Female; Glycerides; Humans; Male; Nanoparticles; Polyethylene Glycols; Polysorbates; Rats; Rats, Wistar; Succinates; Vitamin E | 2013 |
Design and characterization of submicron formulation for a poorly soluble drug: the effect of Vitamin E TPGS and other solubilizers on skin permeability enhancement.
Topics: Administration, Cutaneous; Crystallization; Drug Carriers; Drug Compounding; Drug Delivery Systems; Drug Stability; Drug Storage; Excipients; Hypromellose Derivatives; Ibuprofen; Methylcellulose; Particle Size; Permeability; Poloxamer; Polyethylene Glycols; Povidone; Skin Absorption; Solubility; Thermodynamics; Vitamin E | 2012 |
Formulation, antileukemia mechanism, pharmacokinetics, and biodistribution of a novel liposomal emodin.
Topics: Animals; Antineoplastic Agents; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Emodin; Female; Humans; Leukemia L1210; Liposomes; Liver Neoplasms; Male; Mice; Mice, Inbred ICR; Particle Size; Phosphatidylethanolamines; Polyethylene Glycols; Random Allocation; Tissue Distribution; Transferrin; Vitamin E | 2012 |
Design and evaluation of D-α tocopheryl polyethylene glycol 1000 succinate emulsified poly-ϵ-caprolactone nanoparticles for protein/peptide drug delivery.
Topics: Caco-2 Cells; Circular Dichroism; Drug Delivery Systems; Emulsions; Humans; Nanoparticles; Peptides; Polyesters; Polyethylene Glycols; Proteins; Serum Albumin, Bovine; Solubility; Vitamin E | 2013 |
Efficacy and biodistribution of tocopheryl polyethylene glycol succinate noncovalent functionalized single walled nanotubes loading doxorubicin in sarcoma bearing mouse model.
Topics: Animals; Cell Line, Tumor; Doxorubicin; Materials Testing; Metabolic Clearance Rate; Mice; Nanocapsules; Nanotubes, Carbon; Organ Specificity; Sarcoma; Tissue Distribution; Treatment Outcome; Vitamin E | 2012 |
Increased absorption of mangiferin in the gastrointestinal tract and its mechanism of action by absorption enhancers in rats.
Topics: Acrylates; Adhesiveness; Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Biological Availability; Deoxycholic Acid; Dose-Response Relationship, Drug; Excipients; Intestinal Absorption; Intestinal Mucosa; Permeability; Polyethylene Glycols; Random Allocation; Rats; Rats, Wistar; Surface-Active Agents; Suspensions; Up-Regulation; Vitamin E; Xanthones | 2013 |
Polymer micelles for delayed release of therapeutics from drug-releasing surfaces with nanotubular structures.
Topics: Delayed-Action Preparations; Drug Carriers; Drug Compounding; Electrochemical Techniques; Gentamicins; Hydrophobic and Hydrophilic Interactions; Indomethacin; Kinetics; Micelles; Microscopy, Electron, Scanning; Nanotubes; Poloxamer; Polyethylene Glycols; Propylene Glycols; Solubility; Succinates; Titanium; Vitamin E | 2012 |
Novel lipid based oral formulation of curcumin: development and optimization by design of experiments approach.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Biological Availability; Curcumin; Drug Carriers; Excipients; Glycerides; Male; Organic Chemicals; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Solubility; Surface-Active Agents; Vitamin E | 2012 |
Monitoring the dissolution of Active Pharmaceutical Ingredient and TPGS in real time via IR spectroscopy during the manufacturing of liquid dosage formulation.
Topics: Calibration; Chemistry, Pharmaceutical; Computer Systems; Dosage Forms; Excipients; Models, Chemical; Online Systems; Polyethylene Glycols; Reference Standards; Software; Solubility; Spectroscopy, Fourier Transform Infrared; Technology, Pharmaceutical; Temperature; Vitamin E | 2012 |
Co-delivery of paclitaxel and survivin shRNA by pluronic P85-PEI/TPGS complex nanoparticles to overcome drug resistance in lung cancer.
Topics: Animals; Apoptosis; Cell Cycle; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; Imines; Inhibitor of Apoptosis Proteins; Lung Neoplasms; Male; Mice; Mice, Nude; Paclitaxel; Poloxalene; Polyethylene Glycols; Polyethylenes; RNA, Small Interfering; Survivin; Vitamin E | 2012 |
Optimization of formulation and process parameters for the production of nanosuspension by wet media milling technique: effect of Vitamin E TPGS and nanocrystal particle size on oral absorption.
Topics: Absorption; Animals; Chemistry, Pharmaceutical; Dogs; Drug Stability; Male; Nanoparticles; Particle Size; Polyethylene Glycols; Solubility; Suspensions; Technology, Pharmaceutical; Vitamin E | 2012 |
Vitamin E TPGS prodrug micelles for hydrophilic drug delivery with neuroprotective effects.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cisplatin; Drug Carriers; Hep G2 Cells; Humans; Hydrophobic and Hydrophilic Interactions; Micelles; Neuroprotective Agents; Polyethylene Glycols; Prodrugs; Vitamin E | 2012 |
Pharmacokinetics and tissue distribution of amphotericin B following oral administration of three lipid-based formulations to rats.
Topics: Administration, Oral; Amphotericin B; Animals; Anti-Infective Agents; Chromatography, High Pressure Liquid; Drug Compounding; Drug Delivery Systems; Excipients; Kidney; Lipids; Lung; Male; Oleic Acids; Phosphatidylethanolamines; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Solubility; Tissue Distribution; Vitamin E | 2013 |
Development and evaluation of tocopherol-rich argan oil-based nanoemulsions as vehicles possessing anticancer activity.
Topics: Animals; Antineoplastic Agents; Biocompatible Materials; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Drug Screening Assays, Antitumor; Emulsions; Female; Inhibitory Concentration 50; Mice; Models, Chemical; Nanomedicine; Plant Oils; Polyethylene Glycols; Rats; Tocopherols; Vitamin E | 2012 |
Enhancement of corneal permeation of riboflavin-5'-phosphate through vitamin E TPGS: a promising approach in corneal trans-epithelial cross linking treatment.
Topics: Administration, Ophthalmic; Animals; Antioxidants; Biological Availability; Cornea; Corneal Topography; Cross-Linking Reagents; Dextrans; Drug Carriers; Flavin Mononucleotide; Humans; In Vitro Techniques; Polyethylene Glycols; Prodrugs; Swine; Vitamin E | 2013 |
Development of curcumin nanocrystal: physical aspects.
Topics: Carboxymethylcellulose Sodium; Chemistry, Pharmaceutical; Coumaric Acids; Curcumin; Drug Stability; Excipients; Hydrogen-Ion Concentration; Hydrolysis; Methane; Nanoparticles; Nanotechnology; Particle Size; Polyethylene Glycols; Polyvinyl Alcohol; Povidone; Pressure; Sodium Dodecyl Sulfate; Solubility; Surface Properties; Technology, Pharmaceutical; Temperature; Vitamin E | 2013 |
Cyclooxygenase-2/prostaglandin E₂ inducing effects of α-tocopheryl polyethylene glycol succinate in lung epithelial cells.
Topics: alpha-Tocopherol; Antioxidants; Apoptosis; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dietary Supplements; Dinoprostone; Enzyme Induction; Excipients; Humans; Lung; Osmolar Concentration; Oxidative Stress; Polyethylene Glycols; Reactive Oxygen Species; Respiratory Mucosa; Surface-Active Agents; Up-Regulation; Vitamin E | 2012 |
A novel drug-phospholipid complex loaded micelle for baohuoside I enhanced oral absorption: in vivo and in vivo evaluations.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Biological Availability; Caco-2 Cells; Chemical Phenomena; Drug Carriers; Drug Compounding; Drug Stability; Drugs, Chinese Herbal; Excipients; Flavonoids; Half-Life; Humans; Intestinal Absorption; Male; Micelles; Phospholipids; Polyethylene Glycols; Random Allocation; Rats; Solubility; Vitamin E | 2013 |
Identifying the correlation between drug/stabilizer properties and critical quality attributes (CQAs) of nanosuspension formulation prepared by wet media milling technology.
Topics: 1-Octanol; Dioctyl Sulfosuccinic Acid; Drug Compounding; Drug Stability; Hypromellose Derivatives; Methylcellulose; Molecular Weight; Nanoparticles; Naproxen; Pharmaceutical Preparations; Poloxamer; Polyethylene Glycols; Sodium Dodecyl Sulfate; Solubility; Surface-Active Agents; Suspensions; Transition Temperature; Vitamin E; Water | 2013 |
Processing challenges with solid dosage formulations containing vitamin E TPGS.
Topics: Colloids; Drug Compounding; Excipients; Particle Size; Polyethylene Glycols; Porosity; Silicon Dioxide; Tablets; Time Factors; Vitamin E | 2013 |
Simultaneous inhibition of metastasis and growth of breast cancer by co-delivery of twist shRNA and paclitaxel using pluronic P85-PEI/TPGS complex nanoparticles.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Carcinoma; Drug Combinations; Female; Genetic Therapy; Imines; Mice; Mice, Inbred BALB C; Mice, Nude; Nanocapsules; Paclitaxel; Poloxalene; Polyethylene Glycols; Polyethylenes; RNA, Small Interfering; Transfection; Treatment Outcome; Vitamin E | 2013 |
Alpha-tocopheryl polyethylene glycol succinate-emulsified poly(lactic-co-glycolic acid) nanoparticles for reversal of multidrug resistance in vitro.
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Emulsions; Humans; Irinotecan; Lactic Acid; Materials Testing; Nanocapsules; Nanoparticles; Neoplasms, Experimental; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vitamin E | 2012 |
Vitamin E D-α-tocopheryl polyethylene glycol 1000 succinate-based nanomedicine.
Topics: Animals; Drug Carriers; Drug Delivery Systems; Humans; Nanomedicine; Nanoparticles; Polyethylene Glycols; Prodrugs; Vitamin E | 2012 |
D-Alpha-tocopherol acid polyethylene glycol 1000 succinate, an effective stabilizer during solidification transformation of baicalin nanosuspensions.
Topics: Crystallization; Drug Compounding; Drug Stability; Excipients; Flavonoids; Freeze Drying; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Molecular Structure; Nanoparticles; Particle Size; Phase Transition; Polyethylene Glycols; Solubility; Succinates; Surface Properties; Suspensions; Vitamin E | 2013 |
Enhanced solubility and oral absorption of sirolimus using D-α-tocopheryl polyethylene glycol succinate micelles.
Topics: Absorption; Animals; Antibiotics, Antineoplastic; Area Under Curve; Drug Carriers; Drug Stability; Lecithins; Male; Mice; Micelles; Particle Size; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Sirolimus; Solubility; Vitamin E; Water | 2013 |
Ultrasound enhanced release of therapeutics from drug-releasing implants based on titania nanotube arrays.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Buffers; Drug Carriers; Drug Delivery Systems; Drug Implants; Equipment Design; Hydrogen-Ion Concentration; Indomethacin; Micelles; Microscopy, Electron, Scanning; Nanotubes; Particle Size; Sonication; Surface Properties; Titanium; Vitamin E | 2013 |
Effects of particle size and surface modification on cellular uptake and biodistribution of polymeric nanoparticles for drug delivery.
Topics: Administration, Oral; Animals; Blood-Brain Barrier; Caco-2 Cells; Chromatography, High Pressure Liquid; Dogs; Drug Carriers; Drug Delivery Systems; Endocytosis; Fluorescent Dyes; Gastrointestinal Tract; Humans; Madin Darby Canine Kidney Cells; Male; Nanoparticles; Particle Size; Polyethylene Glycols; Polystyrenes; Rats; Rats, Sprague-Dawley; Surface Properties; Tissue Distribution; Vitamin E | 2013 |
Drug "supersaturation" states induced by polymeric micelles and liposomes: a mechanistic investigation into permeability enhancements.
Topics: Animals; Hydrocortisone; Liposomes; Micelles; Nasal Mucosa; Permeability; Phospholipids; Polyethylene Glycols; Polymers; Povidone; Powders; Sheep; Solubility; Vitamin E | 2013 |
Targeted co-delivery of docetaxel and siPlk1 by herceptin-conjugated vitamin E TPGS based immunomicelles.
Topics: Animals; Antibodies, Monoclonal, Humanized; Cell Cycle Proteins; Cell Division; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Cytoplasm; Docetaxel; Drug Delivery Systems; Gene Transfer Techniques; Humans; Inhibitory Concentration 50; Light; Mice; Micelles; Microscopy, Electron, Transmission; Particle Size; Polo-Like Kinase 1; Polyethylene Glycols; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; RNA, Small Interfering; Scattering, Radiation; Taxoids; Time-Lapse Imaging; Transfection; Trastuzumab; Vitamin E | 2013 |
Vitamin E-loaded silk fibroin nanofibrous mats fabricated by green process for skin care application.
Topics: Animals; Cell Proliferation; Cell Shape; Cell Survival; Cells, Cultured; Fibroblasts; Fibroins; Green Chemistry Technology; Mice; Micelles; Nanofibers; Oxidative Stress; Polyethylene Glycols; Polymers; Protein Structure, Secondary; Skin Care; Spectroscopy, Fourier Transform Infrared; Succinates; tert-Butylhydroperoxide; Vitamin E; X-Ray Diffraction | 2013 |
A new function of Vitamin E-TPGS in the intestinal lymphatic transport of lipophilic drugs: enhancing the secretion of chylomicrons.
Topics: Animals; Biological Transport; Caco-2 Cells; Chylomicrons; Drug Carriers; Humans; Intestinal Mucosa; Intestines; Lymphatic Vessels; Male; Polyethylene Glycols; Probucol; Rats; Rats, Sprague-Dawley; Vitamin E | 2013 |
Supersaturatable formulations for the enhanced oral absorption of sirolimus.
Topics: Absorption; Administration, Oral; Animals; Biological Availability; Drug Compounding; Excipients; Hypromellose Derivatives; Immunosuppressive Agents; Male; Methylcellulose; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Sirolimus; Sucrose; Vitamin E | 2013 |
Controlled preparation and antitumor efficacy of vitamin E TPGS-functionalized PLGA nanoparticles for delivery of paclitaxel.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chemical Precipitation; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Female; Humans; Lactic Acid; Lung Neoplasms; Mice; Mice, Nude; Microscopy, Electron, Transmission; Nanoparticles; Paclitaxel; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Treatment Outcome; Tumor Burden; Vitamin E; Xenograft Model Antitumor Assays | 2013 |
Targeted co-delivery of docetaxel, cisplatin and herceptin by vitamin E TPGS-cisplatin prodrug nanoparticles for multimodality treatment of cancer.
Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Cell Line, Tumor; Cisplatin; Docetaxel; Drug Carriers; Female; Humans; Mice; Nanoparticles; NIH 3T3 Cells; Polyethylene Glycols; Prodrugs; Taxoids; Trastuzumab; Vitamin E | 2013 |
Preparation and characterization of progesterone dispersions using supercritical carbon dioxide.
Topics: Carbon Dioxide; Chemistry, Pharmaceutical; Crystallization; Excipients; Polyethylene Glycols; Progesterone; Solubility; Time Factors; Vitamin E | 2014 |
Evaluation of progesterone permeability from supercritical fluid processed dispersion systems.
Topics: Administration, Cutaneous; Animals; Ethylene Glycols; Excipients; Mice; Permeability; Polyethylene Glycols; Progesterone; Progestins; Skin; Vitamin E | 2014 |
Trastuzumab-conjugated vitamin E TPGS liposomes for sustained and targeted delivery of docetaxel.
Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Area Under Curve; Breast Neoplasms; Calorimetry, Differential Scanning; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Coumarins; Docetaxel; Drug Carriers; Half-Life; Humans; Liposomes; Male; Microscopy, Confocal; Particle Size; Polyethylene Glycols; Rats, Sprague-Dawley; Receptor, ErbB-2; Spectroscopy, Fourier Transform Infrared; Taxoids; Thiazoles; Trastuzumab; Vitamin E | 2013 |
Multifunctional nanoparticles based on a single-molecule modification for the treatment of drug-resistant cancer.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Drug Design; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluorouracil; Humans; Hydrolysis; Models, Chemical; Nanoparticles; Neoplasms; Paclitaxel; Polyethylene Glycols; Rhodamine 123; Vitamin E | 2013 |
TPGS emulsified zein nanoparticles enhanced oral bioavailability of daidzin: in vitro characteristics and in vivo performance.
Topics: Administration, Oral; Animals; Biological Availability; Biological Transport, Active; Caco-2 Cells; Coumarins; Drug Delivery Systems; Emulsions; Humans; Intestinal Absorption; Isoflavones; Male; Mice; Nanoparticles; Phytoestrogens; Polyethylene Glycols; Solutions; Thiazoles; Vitamin E; Zein | 2013 |
Development of amorphous solid dispersion formulations of a poorly water-soluble drug, MK-0364.
Topics: Amides; Animals; Cannabinoid Receptor Agonists; Excipients; Hexoses; Macaca mulatta; Methylcellulose; Polyethylene Glycols; Polysorbates; Pyridines; Pyrrolidines; Solubility; Surface-Active Agents; Vinyl Compounds; Vitamin E; Water | 2013 |
Paclitaxel-loaded poly(glycolide-co-ε-caprolactone)-b-D-α-tocopheryl polyethylene glycol 2000 succinate nanoparticles for lung cancer therapy.
Topics: Animals; Antineoplastic Agents; Body Weight; Cell Line, Tumor; Cell Survival; Coumarins; Drug Delivery Systems; Humans; Lung Neoplasms; Mice; Mice, Nude; Nanoparticles; Neoplasms, Experimental; Paclitaxel; Polyesters; Polyethylene Glycols; Thiazoles; Vitamin E; Xenograft Model Antitumor Assays | 2013 |
Improved oral bioavailability of fexofenadine hydrochloride using lipid surfactants: ex vivo, in situ and in vivo studies.
Topics: Administration, Oral; Animals; Biological Availability; Calorimetry, Differential Scanning; Drug Carriers; Intestinal Absorption; Lipids; Male; Permeability; Polyethylene Glycols; Rats; Rats, Wistar; Solubility; Spectroscopy, Fourier Transform Infrared; Surface-Active Agents; Terfenadine; Vitamin E | 2014 |
pH-sensitive docetaxel-loaded D-α-tocopheryl polyethylene glycol succinate-poly(β-amino ester) copolymer nanoparticles for overcoming multidrug resistance.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Docetaxel; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Hydrogen-Ion Concentration; Nanoparticles; Particle Size; Polyethylene Glycols; Polymers; Taxoids; Vitamin E | 2013 |
Docetaxel-loaded nanoparticles based on star-shaped mannitol-core PLGA-TPGS diblock copolymer for breast cancer therapy.
Topics: Antineoplastic Agents; Breast Neoplasms; Calorimetry, Differential Scanning; Cell Survival; Chromatography, Gel; Coumarins; Docetaxel; Female; Humans; Inhibitory Concentration 50; Lactic Acid; Magnetic Resonance Spectroscopy; Mannitol; MCF-7 Cells; Molecular Weight; Nanoparticles; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Static Electricity; Taxoids; Thermogravimetry; Thiazoles; Vitamin E; Xenograft Model Antitumor Assays | 2013 |
Synergistic inhibition of breast cancer metastasis by silibinin-loaded lipid nanoparticles containing TPGS.
Topics: Animals; Antineoplastic Agents; Biological Transport; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Drug Carriers; Drug Synergism; Female; Humans; Lung Neoplasms; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Nude; Nanoparticles; Neoplasm Invasiveness; Particle Size; Phosphatidylcholines; Polyethylene Glycols; Silybin; Silymarin; Snail Family Transcription Factors; Solubility; Technology, Pharmaceutical; Time Factors; Tissue Distribution; Transcription Factors; Vitamin E; Wound Healing; Xenograft Model Antitumor Assays | 2013 |
Paclitaxel nanosuspensions coated with P-gp inhibitory surfactants: I. Acute toxicity and pharmacokinetics studies.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Coated Materials, Biocompatible; Mice; Nanoparticles; Paclitaxel; Particle Size; Polyethylene Glycols; Surface-Active Agents; Suspensions; Toxicity Tests, Acute; Vitamin E | 2013 |
Polymeric mixed micelles for delivery of curcumin to multidrug resistant ovarian cancer.
Topics: Antineoplastic Agents; Cell Line, Tumor; Curcumin; Delayed-Action Preparations; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Micelles; Nanocapsules; Ovarian Neoplasms; Poloxamer; Polyethylene Glycols; Treatment Outcome; Vitamin E | 2013 |
Intravitreal administration of dexamethasone-loaded PLGA-TPGS nanoparticles for the treatment of posterior segment diseases.
Topics: Animals; Anti-Inflammatory Agents; Dexamethasone; Diffusion; Eye Diseases; Intravitreal Injections; Lactic Acid; Materials Testing; Metabolic Clearance Rate; Nanocapsules; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Posterior Eye Segment; Rabbits; Tissue Distribution; Vitamin E | 2013 |
Paclitaxel-loaded PCL-TPGS nanoparticles: in vitro and in vivo performance compared with Abraxane®.
Topics: Albumin-Bound Paclitaxel; Albumins; Animals; Calorimetry, Differential Scanning; Cell Line, Tumor; Cell Proliferation; Humans; Male; Nanoparticles; Paclitaxel; Polyesters; Polyethylene Glycols; Polymers; Rats; Rats, Wistar; Vitamin E | 2014 |
Preparation and evaluation in vitro and in vivo of docetaxel loaded mixed micelles for oral administration.
Topics: Administration, Oral; Animals; Chitosan; Docetaxel; Gastrointestinal Tract; Magnetic Resonance Spectroscopy; Male; Micelles; Microscopy, Electron, Transmission; Molecular Weight; Oligosaccharides; Rats; Rats, Wistar; Stearic Acids; Taxoids; Time Factors; Vitamin E | 2014 |
Aqueous nanomicellar formulation for topical delivery of biotinylated lipid prodrug of acyclovir: formulation development and ocular biocompatibility.
Topics: Acyclovir; Administration, Ophthalmic; Antiviral Agents; Biotinylation; Cytokines; Drug Delivery Systems; Epithelium, Corneal; Gene Expression Regulation; Humans; Keratitis, Herpetic; Lipids; Micelles; Nanoparticles; Octoxynol; Particle Size; Polyethylene Glycols; Prodrugs; Real-Time Polymerase Chain Reaction; Surface-Active Agents; Vitamin E | 2014 |
Formulation and optimization of nonionic surfactants emulsified nimesulide-loaded PLGA-based nanoparticles by design of experiments.
Topics: Chemistry, Pharmaceutical; Drug Carriers; Emulsions; Lactic Acid; Nanoparticles; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Polyvinyl Alcohol; Sulfonamides; Surface-Active Agents; Vitamin E | 2014 |
Chitosan-g-TPGS nanoparticles for anticancer drug delivery and overcoming multidrug resistance.
Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Blotting, Western; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Proliferation; Chitosan; Doxorubicin; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Flow Cytometry; Humans; Liver Neoplasms; Mice; Nanoparticles; Polyethylene Glycols; Polymers; Tissue Distribution; Tumor Cells, Cultured; Vitamin E; Xenograft Model Antitumor Assays | 2014 |
iRGD conjugated TPGS mediates codelivery of paclitaxel and survivin shRNA for the reversal of lung cancer resistance.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Drug Delivery Systems; Drug Resistance, Neoplasm; Humans; Inhibitor of Apoptosis Proteins; Integrin alphaVbeta3; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Nanotechnology; Oligopeptides; Paclitaxel; Permeability; Polyethylene Glycols; RNA Interference; RNA, Small Interfering; Survivin; Vitamin E | 2014 |
Micelles of TPGS modified apigenin phospholipid complex for oral administration: preparation, in vitro and in vivo evaluation.
Topics: Animals; Apigenin; Drug Carriers; Female; Humans; Intestinal Absorption; Male; Materials Testing; Mice; Mice, Nude; Micelles; Molecular Docking Simulation; Phospholipids; Polyethylene Glycols; Polymers; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured; Vitamin E | 2013 |
Impact of surfactants on the crystal growth of amorphous celecoxib.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Celecoxib; Chemistry, Pharmaceutical; Crystallization; Drug Compounding; Drug Stability; Polyethylene Glycols; Polymers; Povidone; Pyrazoles; Sodium Dodecyl Sulfate; Solubility; Sucrose; Sulfonamides; Surface-Active Agents; Temperature; Vitamin E; X-Ray Diffraction | 2014 |
In vitro susceptibilities of wild and drug resistant leishmania donovani amastigote stages to andrographolide nanoparticle: role of vitamin E derivative TPGS for nanoparticle efficacy.
Topics: Animals; Biological Transport; Capsules; Diterpenes; Drug Interactions; Drug Resistance; Drug Stability; Female; Kinetics; Lactic Acid; Leishmania donovani; Male; Mice; Mice, Inbred BALB C; Nanoparticles; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vitamin E | 2013 |
D-α-tocopheryl polyethylene glycol 1000 succinate: a view from FTICR MS and tandem MS.
Topics: Cyclotrons; Metals; Spectroscopy, Fourier Transform Infrared; Tandem Mass Spectrometry; Vitamin E | 2014 |
The reduction of anti-cancer drug antagonism by the spatial protection of drugs with PLA-TPGS nanoparticles.
Topics: Antineoplastic Agents; Cell Death; Colloids; Coumarins; Drug Antagonism; Endocytosis; Humans; MCF-7 Cells; Nanoparticles; Polyesters; Polyethylene Glycols; Vitamin E | 2014 |
"Nok": a phytosterol-based amphiphile enabling transition-metal-catalyzed couplings in water at room temperature.
Topics: Catalysis; Hydrophobic and Hydrophilic Interactions; Nanoparticles; Phytosterols; Polyethylene Glycols; Sitosterols; Succinates; Surface-Active Agents; Temperature; Transition Elements; Vitamin E; Water | 2014 |
Solid dispersion of berberine-phospholipid complex/TPGS 1000/SiO₂: preparation, characterization and in vivo studies.
Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Berberine; Biological Availability; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Dosage Forms; Drug Carriers; Intestinal Absorption; Intestinal Mucosa; Intestines; Male; Microscopy, Electron, Scanning; Phospholipids; Polyethylene Glycols; Rats, Sprague-Dawley; Silicon Dioxide; Solubility; Spectroscopy, Fourier Transform Infrared; Technology, Pharmaceutical; Vitamin E | 2014 |
Liposomal oxymatrine in hepatic fibrosis treatment: formulation, in vitro and in vivo assessment.
Topics: Alkaloids; Animals; Carbon Tetrachloride; Chemistry, Pharmaceutical; Cytoprotection; Dimethylnitrosamine; Drug Carriers; Kinetics; Liposomes; Liver; Liver Cirrhosis, Experimental; Male; Mice, Inbred ICR; Protective Agents; Quinolizines; Solubility; Technology, Pharmaceutical; Vitamin E | 2014 |
Surface-modified solid lipid nanoparticles for oral delivery of docetaxel: enhanced intestinal absorption and lymphatic uptake.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Docetaxel; Drug Delivery Systems; Intestinal Absorption; Lipids; Lymphatic System; Male; Nanomedicine; Nanoparticles; Polyethylene Glycols; Polysorbates; Rats; Rats, Sprague-Dawley; Surface Properties; Taxoids; Triglycerides; Vitamin E | 2014 |
D-alpha-tocopheryl polyethylene glycol succinate (TPGS) induces cell cycle arrest and apoptosis selectively in Survivin-overexpressing breast cancer cells.
Topics: Apoptosis; Base Sequence; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; DNA Primers; Enzyme-Linked Immunosorbent Assay; Female; Humans; Inhibitor of Apoptosis Proteins; Polyethylene Glycols; Real-Time Polymerase Chain Reaction; Survivin; Vitamin E | 2014 |
Enhanced tumor delivery of gemcitabine via PEG-DSPE/TPGS mixed micelles.
Topics: Animals; Antimetabolites, Antineoplastic; Cathepsin B; Cell Line, Tumor; Cell Proliferation; Cytidine Deaminase; Deoxycytidine; Drug Delivery Systems; Female; Gemcitabine; Humans; Mice; Micelles; Phosphatidylethanolamines; Polyethylene Glycols; Vitamin E; Xenograft Model Antitumor Assays | 2014 |
Directed self-assembled nanoparticles of probucol improve oral delivery: fabrication, performance and correlation.
Topics: Administration, Oral; Animals; Anticholesteremic Agents; Biological Availability; Caco-2 Cells; Drug Carriers; Humans; Male; Nanoparticles; Particle Size; Polyethylene Glycols; Polysorbates; Probucol; Rats, Sprague-Dawley; Surface-Active Agents; Vitamin E | 2014 |
The cancer targeting potential of D-α-tocopheryl polyethylene glycol 1000 succinate tethered multi walled carbon nanotubes.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Doxorubicin; Drug Delivery Systems; Humans; Mice; Mice, Inbred BALB C; Nanotubes, Carbon; Neoplasms; Polyethylene Glycols; Vitamin E | 2014 |
Effect of high-pressure homogenization on formulation of TPGS loaded nanoemulsion of rutin - pharmacodynamic and antioxidant studies.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biological Availability; Chemistry, Pharmaceutical; Disease Models, Animal; Emulsions; Excipients; Free Radical Scavengers; Male; Nanoparticles; Particle Size; Polymers; Propylene Glycols; Rats; Rats, Wistar; Rutin; Solubility; Surface-Active Agents; Viscosity; Vitamin E | 2015 |
Combinational delivery of hydrophobic and hydrophilic anticancer drugs in single nanoemulsions to treat MDR in cancer.
Topics: Adenosine Triphosphatases; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Cell Line, Tumor; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Emulsions; Female; Fluorouracil; Humans; Hydrophobic and Hydrophilic Interactions; Inhibitory Concentration 50; Mice; Mice, Nude; Nanomedicine; Neoplasm Transplantation; Paclitaxel; Polyethylene Glycols; Skin Neoplasms; Vitamin E | 2014 |
Improvement of the antitumor activity of poorly soluble sapacitabine (CS-682) by using Soluplus® as a surfactant.
Topics: Animals; Antineoplastic Agents; Arabinonucleosides; Cell Line, Tumor; Cytosine; Dose-Response Relationship, Drug; Mice; Polyethylene Glycols; Polysorbates; Polyvinyls; Solubility; Surface-Active Agents; Survival Analysis; Vitamin E | 2014 |
Solubilized delivery of paliperidone palmitate by D-alpha-tocopheryl polyethylene glycol 1000 succinate micelles for improved short-term psychotic management.
Topics: Animals; Antipsychotic Agents; Apomorphine; Catalepsy; Chemistry, Pharmaceutical; Drug Compounding; Drug Delivery Systems; Mice; Micelles; Paliperidone Palmitate; Particle Size; Polyethylene Glycols; Psychotic Disorders; Vitamin E | 2016 |
A TPGS-incorporating nanoemulsion of paclitaxel circumvents drug resistance in breast cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Cycle; Cell Survival; Drug Carriers; Drug Resistance, Neoplasm; Emulsions; Humans; Inhibitory Concentration 50; Mammary Neoplasms, Experimental; MCF-7 Cells; Membrane Potential, Mitochondrial; Mice, Nude; Nanostructures; Paclitaxel; Vitamin E; Xenograft Model Antitumor Assays | 2014 |
Curcumin-loaded solid lipid nanoparticles with Brij78 and TPGS improved in vivo oral bioavailability and in situ intestinal absorption of curcumin.
Topics: Administration, Oral; Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Curcumin; Drug Carriers; Drug Compounding; Half-Life; Intestinal Absorption; Intestine, Small; Lipids; Male; Metabolic Clearance Rate; Models, Chemical; Models, Statistical; Nanoparticles; Nanotechnology; Particle Size; Polyethylene Glycols; Rats, Wistar; Solubility; Surface-Active Agents; Technology, Pharmaceutical; Vitamin E | 2016 |
Targeted cancer theranostics using alpha-tocopheryl succinate-conjugated multifunctional dendrimer-entrapped gold nanoparticles.
Topics: Animals; Cell Line, Tumor; Contrast Media; Dendrimers; Folic Acid; Gold; Humans; Male; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasms; Polyethylene Glycols; Tomography, X-Ray Computed; Vitamin E | 2014 |
Star-shape redox-responsive PEG-sheddable copolymer of disulfide-linked polyethylene glycol-lysine-di-tocopherol succinate for tumor-triggering intracellular doxorubicin rapid release: head-to-head comparison.
Topics: Antibiotics, Antineoplastic; Apoptosis; Biological Transport; Cell Nucleus; Doxorubicin; Drug Carriers; Drug Compounding; Drug Resistance, Neoplasm; Endosomes; Female; Humans; Kinetics; MCF-7 Cells; Micelles; Nanoparticles; Particle Size; Polyethylene Glycols; Vitamin E | 2014 |
Optimization of dexamethasone mixed nanomicellar formulation.
Topics: Administration, Ophthalmic; Animals; Cells, Cultured; Chemistry, Pharmaceutical; Dexamethasone; Epithelium, Corneal; Glucocorticoids; Kinetics; Least-Squares Analysis; Micelles; Models, Statistical; Nanoparticles; Nanotechnology; Octoxynol; Ophthalmic Solutions; Particle Size; Polyethylene Glycols; Proton Magnetic Resonance Spectroscopy; Rabbits; Solubility; Surface Properties; Technology, Pharmaceutical; Viscosity; Vitamin E | 2014 |
A novel oleanolic acid-loaded PLGA-TPGS nanoparticle for liver cancer treatment.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Coumarins; Delayed-Action Preparations; Drug Carriers; Drug Liberation; Hep G2 Cells; Humans; Lactic Acid; Liver Neoplasms; Nanoparticles; Oleanolic Acid; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Thiazoles; Vitamin E | 2015 |
Stimuli-responsive polypropylene for the sustained delivery of TPGS and interaction with erythrocytes.
Topics: Erythrocytes; Hemolysis; Humans; Lipid Peroxidation; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Polyethylene Glycols; Polypropylenes; Vitamin E | 2014 |
The efficacy of nimodipine drug delivery using mPEG-PLA micelles and mPEG-PLA/TPGS mixed micelles.
Topics: Animals; Drug Delivery Systems; Male; Micelles; Nimodipine; Particle Size; Polyesters; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Spectroscopy, Fourier Transform Infrared; Surface Properties; Vitamin E | 2014 |
Dendrimer-TPGS mixed micelles for enhanced solubility and cellular toxicity of taxanes.
Topics: Animals; Cell Death; Cell Line; Cell Survival; Dendrimers; Docetaxel; Hemolysis; Humans; Hydrogen-Ion Concentration; Micelles; Paclitaxel; Particle Size; Polyethylene Glycols; Rats; Solubility; Spectroscopy, Fourier Transform Infrared; Static Electricity; Taxoids; Vitamin E; X-Ray Diffraction | 2014 |
Enhanced oral absorption and therapeutic effect of acetylpuerarin based on D-α-tocopheryl polyethylene glycol 1000 succinate nanoemulsions.
Topics: Administration, Oral; Animals; Emulsions; Infarction, Middle Cerebral Artery; Isoflavones; Male; Nanostructures; Oral Mucosal Absorption; Rats; Rats, Wistar; Vitamin E | 2014 |
Stable phosphatidylcholine-bile salt mixed micelles enhance oral absorption of paclitaxel: preparation and mechanism in rats.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; Cell Line, Tumor; Drug Carriers; Drug Stability; Glycine max; Humans; Intestinal Absorption; Male; Micelles; Paclitaxel; Permeability; Phosphatidylcholines; Poloxamer; Polyethylene Glycols; Polyethyleneimine; Rats; Rats, Wistar; Sodium Cholate; Vitamin E | 2014 |
Physical and dissolution characterization of cilostazol solid dispersions prepared by hot melt granulation (HMG) and thermal adhesion granulation (TAG) methods.
Topics: Bentonite; Calcium Phosphates; Calorimetry, Differential Scanning; Caseins; Cellulose; Cilostazol; Drug Compounding; Hardness; Hot Temperature; Polyethylene Glycols; Pyrrolidines; Solubility; Tablets; Tetrazoles; Vinyl Compounds; Vitamin E | 2014 |
D-α-tocopherol polyethylene glycol succinate-based redox-sensitive paclitaxel prodrug for overcoming multidrug resistance in cancer cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Carriers; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; G2 Phase Cell Cycle Checkpoints; Half-Life; Humans; Mice; Micelles; Ovarian Neoplasms; Oxidation-Reduction; Paclitaxel; Polyethylene Glycols; Prodrugs; Rats; Rats, Sprague-Dawley; Vitamin E | 2014 |
Dorzolamide-loaded PLGA/vitamin E TPGS nanoparticles for glaucoma therapy: Pharmacoscintigraphy study and evaluation of extended ocular hypotensive effect in rabbits.
Topics: Animals; Carbonic Anhydrase Inhibitors; Glaucoma; Intraocular Pressure; Lactic Acid; Microscopy, Electron, Scanning; Nanoparticles; Ocular Hypertension; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits; Radionuclide Imaging; Sulfonamides; Thiophenes; Vitamin A; Vitamin E | 2014 |
Dissolution and bioavailability of lercanidipine-hydroxypropylmethyl cellulose nanoparticles with surfactant.
Topics: Administration, Oral; Biological Availability; Dihydropyridines; Drug Compounding; Humans; Hypromellose Derivatives; Nanoparticles; Particle Size; Poloxamer; Polyethylene Glycols; Solubility; Vitamin E | 2015 |
Enhanced effect of pH-sensitive mixed copolymer micelles for overcoming multidrug resistance of doxorubicin.
Topics: Animals; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B; Breast Neoplasms; Cell Line, Tumor; Delayed-Action Preparations; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Histidine; Humans; Hyaluronic Acid; MCF-7 Cells; Mice, Inbred BALB C; Mice, Nude; Micelles; Polyethylene Glycols; Vitamin E | 2014 |
Nitric oxide releasing d-α-tocopheryl polyethylene glycol succinate for enhancing antitumor activity of doxorubicin.
Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Carcinoma, Hepatocellular; Doxorubicin; Drug Carriers; Female; Half-Life; Hep G2 Cells; Humans; Liver Neoplasms; Mice; Micelles; Nitric Oxide; Polyethylene Glycols; Rats, Sprague-Dawley; Sarcoma 180; Tissue Distribution; Vitamin E | 2014 |
TPGS-g-PLGA/Pluronic F68 mixed micelles for tanshinone IIA delivery in cancer therapy.
Topics: Abietanes; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biological Availability; Carcinoma, Hepatocellular; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Hep G2 Cells; Humans; Lactic Acid; Liver Neoplasms; Male; Micelles; Poloxamer; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; Serum Albumin, Bovine; Vitamin E | 2014 |
pH-sensitive nanoparticles of poly(L-histidine)-poly(lactide-co-glycolide)-tocopheryl polyethylene glycol succinate for anti-tumor drug delivery.
Topics: Antibiotics, Antineoplastic; Doxorubicin; Drug Carriers; Drug Screening Assays, Antitumor; Female; Histidine; Humans; Hydrogen-Ion Concentration; Nanoparticles; Polyglactin 910; Vitamin E | 2015 |
Vitamin E-based micelles enhance the anticancer activity of doxorubicin.
Topics: alpha-Tocopherol; Animals; Antibiotics, Antineoplastic; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Doxorubicin; Drug Delivery Systems; Excipients; Female; Humans; Inhibitory Concentration 50; MCF-7 Cells; Mice; Mice, Nude; Micelles; Polyethylene Glycols; Survival Rate; Vitamin E | 2014 |
Novel nelfinavir mesylate loaded d-α-tocopheryl polyethylene glycol 1000 succinate micelles for enhanced pediatric anti HIV therapy: In vitro characterization and in vivo evaluation.
Topics: Animals; Anti-HIV Agents; HIV Infections; Male; Micelles; Nelfinavir; Rats; Rats, Wistar; Vitamin E | 2014 |
Combinatorial delivery of Crizotinib-Palbociclib-Sildenafil using TPGS-PLA micelles for improved cancer treatment.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Proliferation; Cell Survival; Crizotinib; Drug Carriers; Drug Compounding; Drug Liberation; Humans; Inhibitory Concentration 50; Micelles; Molecular Structure; Piperazines; Polyethylene Glycols; Purines; Pyrazoles; Pyridines; Sildenafil Citrate; Sulfonamides; Vitamin E | 2014 |
The Competitive influence of Li+, Na+, K+, Ag+, and H+ on the fragmentation of a PEGylated polymeric excipient.
Topics: Cations; Excipients; Hydrogen; Metals, Alkali; Polyethylene Glycols; Silver; Tandem Mass Spectrometry; Vitamin E | 2015 |
D-α-tocopheryl polyethylene glycol 1000 succinate-containing vehicles provide no detectable chemoprotection from oxidative damage.
Topics: Adrenal Glands; alpha-Tocopherol; Animals; Drug Carriers; Female; Liver; Male; Oxidation-Reduction; Oxidative Stress; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Thiobarbiturates; Vitamin E | 2015 |
mPEG-b-PCL/TPGS mixed micelles for delivery of resveratrol in overcoming resistant breast cancer.
Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Carriers; Drug Tolerance; Humans; Micelles; Polyesters; Polyethylene Glycols; Resveratrol; Stilbenes; Vitamin E | 2015 |
Nanomicellar Topical Aqueous Drop Formulation of Rapamycin for Back-of-the-Eye Delivery.
Topics: Administration, Ophthalmic; Administration, Topical; Animals; Aqueous Humor; Cells, Cultured; Chemistry, Pharmaceutical; Drug Delivery Systems; Epithelial Cells; Epithelium, Corneal; Humans; Male; Ophthalmic Solutions; Polyethylene Glycols; Rabbits; Retinal Pigment Epithelium; Sirolimus; Tissue Distribution; Vitamin E | 2015 |
TPGS-stabilized NaYbF4:Er upconversion nanoparticles for dual-modal fluorescent/CT imaging and anticancer drug delivery to overcome multi-drug resistance.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Cell Death; Cell Survival; Drug Delivery Systems; Drug Resistance, Multiple; Fluorescence; Humans; Luminescence; MCF-7 Cells; Mice, Nude; Nanoparticles; Oleic Acid; Polyethylene Glycols; Spectroscopy, Fourier Transform Infrared; Thermogravimetry; Tomography, X-Ray Computed; Vitamin E; Ytterbium | 2015 |
Fabrication and evaluation of celecoxib microparticle surface modified by hydrophilic cellulose and surfactant.
Topics: Celecoxib; Excipients; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Hypromellose Derivatives; Microscopy, Electron, Scanning; Microspheres; Particle Size; Polyethylene Glycols; Pyrazoles; Solubility; Sulfonamides; Surface Properties; Surface-Active Agents; Vitamin E; X-Ray Diffraction | 2015 |
Enhanced antitumor efficacy of vitamin E TPGS-emulsified PLGA nanoparticles for delivery of paclitaxel.
Topics: Animals; Cell Line, Tumor; Ethanol; Female; Humans; Lactic Acid; Mice; Mice, Nude; Nanoparticles; Paclitaxel; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vitamin E; Water; Xenograft Model Antitumor Assays | 2014 |
Theranostic vitamin E TPGS micelles of transferrin conjugation for targeted co-delivery of docetaxel and ultra bright gold nanoclusters.
Topics: Animals; Breast Neoplasms; Cell Line; Docetaxel; Drug Carriers; Flow Cytometry; Gold; Humans; Metal Nanoparticles; Mice; Mice, SCID; Micelles; Microscopy, Electron, Transmission; NIH 3T3 Cells; Particle Size; Polyethylene Glycols; Taxoids; Transferrin; Vitamin E | 2015 |
Enhanced antifungal effects of amphotericin B-TPGS-b-(PCL-ran-PGA) nanoparticles in vitro and in vivo.
Topics: Amphotericin B; Animals; Antifungal Agents; Candida albicans; Candidiasis; Colony Count, Microbial; Drug Carriers; Ethylene Glycols; Kidney; Liver; Mice; Nanoparticles; Polyesters; Polyethylene Glycols; Vitamin E | 2014 |
Reversal of doxorubicin resistance in breast cancer by mitochondria-targeted pH-responsive micelles.
Topics: Animals; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Death; Cell Proliferation; Doxorubicin; Drug Resistance, Neoplasm; Endocytosis; Female; Humans; Hydrogen-Ion Concentration; MCF-7 Cells; Membrane Potential, Mitochondrial; Mice, Inbred BALB C; Mice, Nude; Micelles; Microscopy, Electron, Transmission; Mitochondria; Polymethacrylic Acids; Rats, Sprague-Dawley; Tissue Distribution; Vitamin E | 2015 |
TPGS-chitosome as an effective oral delivery system for improving the bioavailability of Coenzyme Q10.
Topics: Administration, Oral; Animals; Antioxidants; Biological Availability; Caco-2 Cells; Cell Line, Tumor; Chemistry, Pharmaceutical; Chitosan; Drug Delivery Systems; Humans; Liposomes; Male; Particle Size; Polyethylene Glycols; Powders; Rats; Rats, Sprague-Dawley; Ubiquinone; Vitamin E | 2015 |
Preparation, in vitro and in vivo evaluation of polymeric nanoparticles based on hyaluronic acid-poly(butyl cyanoacrylate) and D-alpha-tocopheryl polyethylene glycol 1000 succinate for tumor-targeted delivery of morin hydrate.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Drug Carriers; Enbucrilate; Flavonoids; Humans; Hyaluronic Acid; Mice; Nanoparticles; Vitamin E | 2015 |
pH-responsive polymeric micelles based on poly(2-ethyl-2-oxazoline)-poly(D,L-lactide) for tumor-targeting and controlled delivery of doxorubicin and P-glycoprotein inhibitor.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biocompatible Materials; Cations; Dioxanes; Doxorubicin; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Hydrogen-Ion Concentration; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Micelles; Microscopy, Fluorescence; Oxazoles; Polyesters; Polyethylene Glycols; Polymers; Vitamin E | 2015 |
TPGS2k/PLGA nanoparticles for overcoming multidrug resistance by interfering mitochondria of human alveolar adenocarcinoma cells.
Topics: Adenosine Triphosphate; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Camptothecin; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Irinotecan; Lactic Acid; Mitochondria; Nanoparticles; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vitamin E | 2015 |
Co-delivery of docetaxel and Poloxamer 235 by PLGA-TPGS nanoparticles for breast cancer treatment.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Docetaxel; Drug Carriers; Drug Resistance, Multiple; Female; Humans; Lactic Acid; MCF-7 Cells; Nanoparticles; Particle Size; Poloxamer; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Taxoids; Vitamin E | 2015 |
Novel in situ gel systems based on P123/TPGS mixed micelles and gellan gum for ophthalmic delivery of curcumin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cornea; Curcumin; Drug Carriers; Drug Liberation; Factor Analysis, Statistical; Hydrophobic and Hydrophilic Interactions; Inflammation; Irritants; Kinetics; Male; Micelles; Particle Size; Permeability; Poloxalene; Polyethylene Glycols; Polysaccharides, Bacterial; Rabbits; Sodium Dodecyl Sulfate; Solubility; Vitamin E; Water | 2015 |
Synergistic effect of pH-responsive folate-functionalized poloxamer 407-TPGS-mixed micelles on targeted delivery of anticancer drugs.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Synergism; Folic Acid; Humans; Hydrogen-Ion Concentration; Micelles; Poloxamer; Polyethylene Glycols; Vitamin E | 2015 |
Nanoformulation of D-α-tocopheryl polyethylene glycol 1000 succinate-b-poly(ε-caprolactone-ran-glycolide) diblock copolymer for siRNA targeting HIF-1α for nasopharyngeal carcinoma therapy.
Topics: Animals; Antineoplastic Agents; Carcinoma; Cell Line, Tumor; Cell Survival; Drug Carriers; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Nanoparticles; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Polyesters; Polyethylene Glycols; RNA, Small Interfering; Vitamin E | 2015 |
Antifungal efficacy of itraconazole-loaded TPGS-b-(PCL-ran-PGA) nanoparticles.
Topics: Animals; Antifungal Agents; Candida albicans; Cell Survival; HeLa Cells; Humans; Itraconazole; Mice; Nanoparticles; Polyethylene Glycols; Vitamin E | 2015 |
Using in situ Raman spectroscopy to study the drug precipitation inhibition and supersaturation mechanism of Vitamin E TPGS from self-emulsifying drug delivery systems (SEDDS).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Drug Carriers; Drug Delivery Systems; Emulsions; Hydrogen Bonding; Indomethacin; Kinetics; Polyethylene Glycols; Probucol; Spectrum Analysis, Raman; Vitamin E | 2015 |
Lecithin/TPGS-based spray-dried self-microemulsifying drug delivery systems: In vitro pulmonary deposition and cytotoxicity.
Topics: Administration, Inhalation; Aerosols; Atorvastatin; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Desiccation; Dose-Response Relationship, Drug; Drug Carriers; Drug Stability; Emulsions; Humans; Inhibitory Concentration 50; Lecithins; Lung; Lung Neoplasms; Particle Size; Polyethylene Glycols; Powders; Solubility; Surface-Active Agents; Technology, Pharmaceutical; Vitamin E | 2015 |
Doxorubicin-loaded star-shaped copolymer PLGA-vitamin E TPGS nanoparticles for lung cancer therapy.
Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Cell Line, Tumor; Cell Survival; Delayed-Action Preparations; Diffusion; Doxorubicin; Lactic Acid; Lung Neoplasms; Mice; Mice, Inbred BALB C; Nanocapsules; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Treatment Outcome; Vitamin E | 2015 |
Blended nanoparticle system based on miscible structurally similar polymers: a safe, simple, targeted, and surprisingly high efficiency vehicle for cancer therapy.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biocompatible Materials; Cell Line, Tumor; Cell Survival; Docetaxel; Drug Delivery Systems; Drug Resistance, Neoplasm; Endocytosis; Female; Folic Acid; HeLa Cells; Humans; MCF-7 Cells; Mice; Mice, SCID; Nanoparticles; Neoplasms; Particle Size; Polyethylene Glycols; Polyglactin 910; Polyglycolic Acid; Polymers; Taxoids; Vitamin E | 2015 |
Novel PLGA-based nanoparticles for the oral delivery of insulin.
Topics: Administration, Oral; alpha-Tocopherol; Animals; Diabetes Mellitus, Experimental; Drug Carriers; Emulsions; Glucose; Insulin; Lactic Acid; Male; Nanoparticles; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Vitamin E | 2015 |
Fabrication of genistein-loaded biodegradable TPGS-b-PCL nanoparticles for improved therapeutic effects in cervical cancer cells.
Topics: Animals; Antineoplastic Agents; Drug Carriers; Female; Genistein; HeLa Cells; Humans; Mice; Mice, Nude; Nanoparticles; Uterine Cervical Neoplasms; Vitamin E; Xenograft Model Antitumor Assays | 2015 |
Vitamin E-TPGS stabilized self-assembled tripeptide nanostructures for drug delivery.
Topics: Aspirin; Cell Line; Cell Survival; Curcumin; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Drug Liberation; Eosine Yellowish-(YS); Humans; Hydrophobic and Hydrophilic Interactions; Keratinocytes; MCF-7 Cells; Nanostructures; Oligopeptides; Particle Size; Polyethylene Glycols; Vitamin E | 2015 |
Roles of ligand and TPGS of micelles in regulating internalization, penetration and accumulation against sensitive or resistant tumor and therapy for multidrug resistant tumors.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Proliferation; Docetaxel; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Ligands; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Micelles; Polyethylene Glycols; Taxoids; Vitamin E | 2015 |
Cyclic-RGDfK peptide conjugated succinoyl-TPGS nanomicelles for targeted delivery of docetaxel to integrin receptor over-expressing angiogenic tumours.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Docetaxel; Human Umbilical Vein Endothelial Cells; Humans; Integrins; Male; Micelles; Nanostructures; Neovascularization, Pathologic; Peptides, Cyclic; Polyethylene Glycols; Prostatic Neoplasms; Receptors, Cell Surface; Taxoids; Vitamin E | 2015 |
Enhanced supersaturation and oral absorption of sirolimus using an amorphous solid dispersion based on Eudragit® e.
Topics: Animals; Biological Availability; Biomimetic Materials; Drug Carriers; Drug Stability; Excipients; Gastric Juice; Hydrogen-Ion Concentration; Hydrolysis; Hypromellose Derivatives; Male; Oral Mucosal Absorption; Polyethylene Glycols; Polymethacrylic Acids; Rats; Rats, Sprague-Dawley; Sirolimus; Solubility; Vitamin E | 2015 |
Soluplus®/TPGS-based solid dispersions prepared by hot-melt extrusion equipped with twin-screw systems for enhancing oral bioavailability of valsartan.
Topics: Administration, Oral; Angiotensin II Type 1 Receptor Blockers; Animals; Biological Availability; Chemistry, Pharmaceutical; Drug Carriers; Drug Compounding; Drug Liberation; Hydrogen-Ion Concentration; Male; Polyethylene Glycols; Polyvinyls; Rats; Rats, Sprague-Dawley; Solubility; Valsartan; Vitamin E | 2015 |
In vivo and ex vivo proofs of concept that cetuximab conjugated vitamin E TPGS micelles increases efficacy of delivered docetaxel against triple negative breast cancer.
Topics: Animals; Antineoplastic Agents; Breast; Cell Line, Tumor; Cetuximab; Docetaxel; Drug Carriers; Drug Delivery Systems; Female; Humans; Mice, SCID; Micelles; Polyethylene Glycols; Taxoids; Triple Negative Breast Neoplasms; Vitamin E | 2015 |
Novel nanosystem to enhance the antitumor activity of lapatinib in breast cancer treatment: Therapeutic efficacy evaluation.
Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Drug Carriers; Female; Humans; Lactic Acid; Lapatinib; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Mononuclear Phagocyte System; Nanoparticles; Phagocytosis; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Quinazolines; Tumor Burden; Vitamin E; Xenograft Model Antitumor Assays | 2015 |
An Extrusion Spheronization Approach to Enable a High Drug Load Formulation of a Poorly Soluble Drug with a Low Melting Surfactant.
Topics: Animals; Anti-Retroviral Agents; Chemistry, Pharmaceutical; Dogs; Drug Carriers; Excipients; Freezing; Male; Polyethylene Glycols; Solubility; Surface-Active Agents; Vitamin E; X-Ray Diffraction | 2015 |
Gas-generating TPGS-PLGA microspheres loaded with nanoparticles (NIMPS) for co-delivery of minicircle DNA and anti-tumoral drugs.
Topics: Antibiotics, Antineoplastic; DNA, Circular; Doxorubicin; Drug Carriers; Gases; Gene Expression; Lactic Acid; Microspheres; Nanoparticles; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vitamin E; X-Ray Diffraction | 2015 |
Micelles of d-α-Tocopheryl Polyethylene Glycol 2000 Succinate (TPGS 2K) for Doxorubicin Delivery with Reversal of Multidrug Resistance.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Cell Survival; Doxorubicin; Drug Carriers; Drug Liberation; Drug Resistance, Neoplasm; Female; Humans; Hydrogen-Ion Concentration; MCF-7 Cells; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mice, Nude; Micelles; Polyethylene Glycols; Temperature; Tissue Distribution; Vitamin E | 2015 |
PEGylated γ-tocotrienol isomer of vitamin E: Synthesis, characterization, in vitro cytotoxicity, and oral bioavailability.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Biological Availability; Cell Survival; Chromatography, High Pressure Liquid; Cryoelectron Microscopy; Humans; Magnetic Resonance Spectroscopy; Male; MCF-7 Cells; Molecular Structure; Molecular Weight; Particle Size; Polyethylene Glycols; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Surface Properties; Vitamin E | 2015 |
Porphine functionalized nanoparticles of star-shaped poly(ε-caprolactone)-b-D-α-tocopheryl polyethylene glycol 1000 succinate biodegradable copolymer for chemophotodynamic therapy on cervical cancer.
Topics: Absorbable Implants; Antineoplastic Agents; Combined Modality Therapy; Delayed-Action Preparations; Diffusion; Docetaxel; Female; HeLa Cells; Humans; MCF-7 Cells; Nanocapsules; Photochemotherapy; Polyesters; Polyethylene Glycols; Porphyrins; Radiation-Sensitizing Agents; Taxoids; Treatment Outcome; Uterine Cervical Neoplasms; Vitamin E | 2015 |
Assessing Mixing Quality of a Copovidone-TPGS Hot Melt Extrusion Process with Atomic Force Microscopy and Differential Scanning Calorimetry.
Topics: Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Drug Carriers; Drug Compounding; Hot Temperature; Microscopy, Atomic Force; Polymers; Pyrrolidines; Vinyl Compounds; Vitamin E | 2016 |
TPGS/Phospholipids Mixed Micelles for Delivery of Icariside II to Multidrug-Resistant Breast Cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Inducing Factor; bcl-2-Associated X Protein; Breast Neoplasms; Caco-2 Cells; Caspases; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Flavonoids; Humans; MCF-7 Cells; Mice; Mice, Nude; Micelles; Phospholipids; Proto-Oncogene Proteins c-bcl-2; Vitamin E | 2016 |
Mixed Micelles of Doxorubicin Overcome Multidrug Resistance by Inhibiting the Expression of P-Glycoprotein.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Micelles; Nanocapsules; Neoplasms, Experimental; Phosphatidylethanolamines; Polyethylene Glycols; Treatment Outcome; Vitamin E | 2015 |
D-α-tocopherol polyethylene glycol succinate-based derivative nanoparticles as a novel carrier for paclitaxel delivery.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Drug Delivery Systems; Female; Humans; Lung Neoplasms; MCF-7 Cells; Mice; Micelles; Nanoparticles; Ovarian Neoplasms; Paclitaxel; Particle Size; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Sarcoma; Succinates; Vitamin E | 2015 |
Preparation and in vivo/in vitro evaluation of formononetin phospholipid/vitamin E TPGS micelles.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Carriers; Isoflavones; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Micelles; Particle Size; Phospholipids; Polyethylene Glycols; Vitamin E | 2016 |
Development of megestrol acetate solid dispersion nanoparticles for enhanced oral delivery by using a supercritical antisolvent process.
Topics: Administration, Oral; Animals; Area Under Curve; Biological Availability; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Chromatography, Supercritical Fluid; Crystallography, X-Ray; Hypromellose Derivatives; Intestinal Absorption; Male; Megestrol Acetate; Microscopy, Electron, Scanning; Nanoparticles; Nanotechnology; Polyethylene Glycols; Povidone; Powder Diffraction; Progesterone Congeners; Rats, Sprague-Dawley; Solubility; Surface-Active Agents; Technology, Pharmaceutical; Vitamin E | 2015 |
Preparation of intravenous injection nanoformulation of VESylated gemcitabine by co-assembly with TPGS and its anti-tumor activity in pancreatic tumor-bearing mice.
Topics: alpha-Tocopherol; Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Deoxycytidine; Drug Carriers; Drug Stability; Drug Storage; Female; Gemcitabine; Humans; Injections, Intravenous; Mice; Mice, Inbred BALB C; Mice, Nude; Micelles; Microscopy, Electron, Transmission; Nanoparticles; Pancreatic Neoplasms; Particle Size; Polyethylene Glycols; Prodrugs; Vitamin E | 2015 |
Reversal of multidrug resistance by co-delivery of paclitaxel and lonidamine using a TPGS and hyaluronic acid dual-functionalized liposome for cancer treatment.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Hyaluronic Acid; Indazoles; Lipids; Liposomes; Male; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Neoplasms; Paclitaxel; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Vitamin E | 2015 |
Transferrin receptor-targeted vitamin E TPGS micelles for brain cancer therapy: preparation, characterization and brain distribution in rats.
Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Docetaxel; Drug Carriers; Drug Liberation; Micelles; Particle Size; Rats; Receptors, Transferrin; Taxoids; Vitamin E | 2016 |
Enhanced toxicity and cellular uptake of methotrexate-conjugated nanoparticles in folate receptor-positive cancer cells by decorating with folic acid-conjugated d-α-tocopheryl polyethylene glycol 1000 succinate.
Topics: Breast Neoplasms; Female; Folic Acid; Humans; MCF-7 Cells; Methotrexate; Microscopy, Electron, Scanning; Nanoparticles; Polyethylene Glycols; Spectroscopy, Fourier Transform Infrared; Toxicokinetics; Vitamin E | 2015 |
Co-delivery of docetaxel and chloroquine via PEO-PPO-PCL/TPGS micelles for overcoming multidrug resistance.
Topics: Antineoplastic Agents; Cell Death; Cell Line, Tumor; Chloroquine; Docetaxel; Drug Combinations; Drug Delivery Systems; Drug Liberation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Hemolysis; Humans; Micelles; Polyesters; Polyethylene Glycols; Taxoids; Vitamin E | 2015 |
Docetaxel (DTX)-loaded polydopamine-modified TPGS-PLA nanoparticles as a targeted drug delivery system for the treatment of liver cancer.
Topics: Animals; Carcinoma, Hepatocellular; Docetaxel; Drug Delivery Systems; Hep G2 Cells; Humans; Indoles; Lactic Acid; Liver Neoplasms, Experimental; Mice; Mice, Nude; Nanoparticles; Polyesters; Polyethylene Glycols; Polymers; Taxoids; Vitamin E; Xenograft Model Antitumor Assays | 2016 |
pH-Sensitive self-assembling nanoparticles for tumor near-infrared fluorescence imaging and chemo-photodynamic combination therapy.
Topics: Animals; Cell Line, Tumor; Chlorophyllides; Doxorubicin; Female; Humans; Hydrogen-Ion Concentration; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasms, Experimental; Optical Imaging; Photochemotherapy; Polyethylene Glycols; Porphyrins; Vitamin E; Xenograft Model Antitumor Assays | 2016 |
Genistein-loaded nanoparticles of star-shaped diblock copolymer mannitol-core PLGA-TPGS for the treatment of liver cancer.
Topics: Animals; Drug Carriers; Genistein; Hep G2 Cells; Humans; Lactic Acid; Liver Neoplasms; Mannitol; Mice; Mice, SCID; Nanoparticles; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vitamin E; Xenograft Model Antitumor Assays | 2016 |
The effects of quercetin-loaded PLGA-TPGS nanoparticles on ultraviolet B-induced skin damages in vivo.
Topics: Animals; Antioxidants; Cell Line; Drug Carriers; Female; Humans; Keratinocytes; Lactic Acid; Mice; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Quercetin; Radiation Injuries, Experimental; Skin; Skin Diseases; Ultraviolet Rays; Vitamin E | 2016 |
Physical characterization and in vivo pharmacokinetic study of self-assembling amphotericin B-loaded lecithin-based mixed polymeric micelles.
Topics: Administration, Intravenous; Administration, Oral; Amphotericin B; Animals; Biological Availability; HT29 Cells; Humans; Lecithins; Male; Micelles; Microscopy, Electron, Transmission; Particle Size; Phosphatidylethanolamines; Polyethylene Glycols; Polymers; Rats, Sprague-Dawley; Solubility; Time Factors; Vitamin E | 2015 |
Self-emulsifying excipient platform for improving technological properties of alginate-hydroxypropylcellulose pellets.
Topics: Alginates; Calorimetry, Differential Scanning; Cellulose; Chemistry, Pharmaceutical; Crystallization; Drug Liberation; Emulsions; Excipients; Glucuronic Acid; Glycerides; Hexuronic Acids; Hydrogen-Ion Concentration; Ibuprofen; Particle Size; Pectins; Polyethylene Glycols; Solubility; Technology, Pharmaceutical; Vitamin E | 2016 |
Improved antitumor activity of epirubicin-loaded CXCR4-targeted polymeric nanoparticles in liver cancers.
Topics: Animals; Antibiotics, Antineoplastic; Cell Survival; Drug Liberation; Epirubicin; Hep G2 Cells; Humans; Lactic Acid; Liver Neoplasms; Mice; Microscopy, Electron, Transmission; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Treatment Outcome; Vitamin E | 2016 |
Omega-3 fatty acids incorporated colloidal systems for the delivery of Angelica gigas Nakai extract.
Topics: Administration, Oral; Angelica; Animals; Benzopyrans; Butyrates; Colloids; Drug Carriers; Drug Delivery Systems; Drug Liberation; Emulsions; Fatty Acids, Omega-3; Intestinal Absorption; Intestinal Mucosa; Male; Plant Extracts; Polyethylene Glycols; Rats, Sprague-Dawley; Vitamin E | 2016 |
Evaluation of TPGS-modified thermo-sensitive Pluronic PF127 hydrogel as a potential carrier to reverse the resistance of P-gp-overexpressing SMMC-7721 cell lines.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Line, Tumor; Cell Survival; Docetaxel; Drug Carriers; Drug Evaluation, Preclinical; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Liver Neoplasms; Mice, Inbred BALB C; Mice, Nude; Microscopy, Electron, Scanning; Poloxamer; Polyethylene Glycols; Taxoids; Temperature; Tumor Burden; Vitamin E; Xenograft Model Antitumor Assays | 2016 |
Enhancement of Curcumin Solubility by Phase Change from Crystalline to Amorphous in Cur-TPGS Nanosuspension.
Topics: alpha-Tocopherol; Chemistry, Pharmaceutical; Crystallization; Curcuma; Curcumin; Drug Stability; Nanotechnology; Particle Size; Polyethylene Glycols; Powders; Solubility; Vitamin E | 2016 |
Novel Soluplus(®)-TPGS mixed micelles for encapsulation of paclitaxel with enhanced in vitro cytotoxicity on breast and ovarian cancer cell lines.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Drug Compounding; Drug Liberation; Female; Humans; Immunoblotting; MCF-7 Cells; Micelles; Microscopy, Electron, Transmission; Nanoparticles; Ovarian Neoplasms; Paclitaxel; Poly(ADP-ribose) Polymerases; Polyethylene Glycols; Polyvinyls; Solubility; Vitamin E | 2016 |
Comparison of poly(ε-caprolactone) chain lengths of poly(ε-caprolactone)-co-d-α-tocopheryl-poly(ethylene glycol) 1000 succinate nanoparticles for enhancement of quercetin delivery to SKBR3 breast cancer cells.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Drug Delivery Systems; Female; Humans; Nanoparticles; Particle Size; Polyesters; Polyethylene Glycols; Quercetin; Succinates; Vitamin E | 2016 |
Large amino acid transporter 1 mediated glutamate modified docetaxel-loaded liposomes for glioma targeting.
Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Calorimetry, Differential Scanning; Cell Line, Tumor; Cell Survival; Docetaxel; Drug Carriers; Drug Liberation; Glioma; Glutamic Acid; Large Neutral Amino Acid-Transporter 1; Liposomes; Male; Mice; Microscopy, Confocal; Microscopy, Electron, Transmission; Taxoids; Vitamin E | 2016 |
Fluoridated hydroxyapatite: Eu(3+) nanorods-loaded folate-conjugated D-α-tocopheryl polyethylene glycol succinate (vitamin E TPGS) micelles for targeted imaging of cancer cells.
Topics: Cell Survival; Diagnostic Imaging; Drug Stability; Folic Acid; Humans; Hydroxyapatites; MCF-7 Cells; Micelles; Nanoconjugates; Nanotubes; Neoplasms; Polyethylene Glycols; Vitamin E | 2016 |
Liver-targeting Resibufogenin-loaded poly(lactic-co-glycolic acid)-D-α-tocopheryl polyethylene glycol 1000 succinate nanoparticles for liver cancer therapy.
Topics: Animals; Antineoplastic Agents; Apoptosis; Bufanolides; Coumarins; Drug Carriers; Hep G2 Cells; Humans; Lactic Acid; Liver Neoplasms; Male; Mice; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Sprague-Dawley; Thiazoles; Vitamin E | 2016 |
Evaluation in vitro and in vivo of curcumin-loaded mPEG-PLA/TPGS mixed micelles for oral administration.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Area Under Curve; Biological Availability; Chemistry, Pharmaceutical; Curcumin; Drug Liberation; Gastrointestinal Tract; Hydrogen-Ion Concentration; Intestinal Absorption; Kinetics; Male; Metabolic Clearance Rate; Micelles; Microscopy, Electron, Transmission; Particle Size; Polyesters; Polyethylene Glycols; Rats, Wistar; Reproducibility of Results; Vitamin E | 2016 |
Vitamin E TPGS conjugated carbon nanotubes improved efficacy of docetaxel with safety for lung cancer treatment.
Topics: A549 Cells; Alkaline Phosphatase; Animals; Antineoplastic Agents; Apoptosis; Bronchoalveolar Lavage Fluid; Cell Cycle; Cell Survival; Coated Materials, Biocompatible; Coumarins; Docetaxel; Drug Liberation; Humans; L-Lactate Dehydrogenase; Lung; Lung Neoplasms; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Nanotubes, Carbon; Rats; Reactive Oxygen Species; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Taxoids; Thiazoles; Vitamin E | 2016 |
Novel galactosylated biodegradable nanoparticles for hepatocyte-delivery of oridonin.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Survival; Diterpenes, Kaurane; Drug Carriers; Drug Liberation; Galactose; Hep G2 Cells; Hepatocytes; Humans; Lactic Acid; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vitamin E | 2016 |
Transferrin liposomes of docetaxel for brain-targeted cancer applications: formulation and brain theranostics.
Topics: Blood-Brain Barrier; Brain; Brain Neoplasms; Cell Line, Tumor; Chemistry, Pharmaceutical; Docetaxel; Drug Carriers; Humans; Liposomes; Permeability; Polyethylene Glycols; Quantum Dots; Taxoids; Theranostic Nanomedicine; Transferrin; Vitamin E | 2016 |
[Development and characterization of TPGS modified proniosomes of docetaxel].
Topics: Chemistry, Pharmaceutical; Docetaxel; Particle Size; Polyethylene Glycols; Taxoids; Vitamin E | 2015 |
A Lipid Base Formulation for Intramuscular Administration of a Novel Sulfur Donor for Cyanide Antagonism.
Topics: Animals; Antidotes; Cyanides; Drug Carriers; Injections, Intramuscular; Male; Mice; Micelles; Muscle, Skeletal; Phosphatidylethanolamines; Polyethylene Glycols; Solubility; Sulfides; Vitamin E | 2016 |
Core-matched encapsulation of an oleate prodrug into nanostructured lipid carriers with high drug loading capability to facilitate the oral delivery of docetaxel.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Biological Availability; Biological Transport; Docetaxel; Dogs; Drug Carriers; Drug Compounding; Endocytosis; Glycerides; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Intestinal Mucosa; Intestines; Madin Darby Canine Kidney Cells; Nanostructures; Oleic Acids; Particle Size; Prodrugs; Rats; Rats, Sprague-Dawley; Taxoids; Tissue Distribution; Vitamin E | 2016 |
Exemestane encapsulated vitamin E-TPGS-polymeric nanoparticles: preparation, optimization, characterization, and in vitro cytotoxicity assessment.
Topics: Androstadienes; Antineoplastic Agents, Phytogenic; Biological Transport; Cell Survival; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Drug Liberation; Factor Analysis, Statistical; Female; Humans; Hydrogen-Ion Concentration; Kinetics; MCF-7 Cells; Nanoparticles; Particle Size; Polyesters; Vitamin E | 2017 |
Effect of Absorption Behavior of Solubilizers on Drug Dissolution in the Gastrointestinal Tract: Evaluation Based on In Vivo Luminal Concentration-Time Profile of Cilostazol, a Poorly Soluble Drug, and Solubilizers.
Topics: Animals; Area Under Curve; Cilostazol; Dextrans; Dimethyl Sulfoxide; Excipients; Fluorescein-5-isothiocyanate; Gastrointestinal Tract; Intestinal Absorption; Male; Rats; Rats, Wistar; Solubility; Tetrazoles; Vitamin E | 2016 |
Characterization of Heterogeneity and Spatial Distribution of Phases in Complex Solid Dispersions by Thermal Analysis by Structural Characterization and X-ray Micro Computed Tomography.
Topics: Crystallization; Drug Carriers; Drug Compounding; Drug Liberation; Excipients; Felodipine; Pharmaceutical Preparations; Polyethylene Glycols; Polymers; Solubility; Vitamin E; X-Ray Microtomography | 2017 |
Matrix metalloproteinases-2/9-sensitive peptide-conjugated polymer micelles for site-specific release of drugs and enhancing tumor accumulation: preparation and in vitro and in vivo evaluation.
Topics: alpha-Tocopherol; Animals; Cell Death; Cell Line, Tumor; Diagnostic Imaging; Docetaxel; Drug Delivery Systems; Drug Liberation; Endocytosis; Fluorescence Resonance Energy Transfer; Humans; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice, Inbred BALB C; Mice, Nude; Micelles; Neoplasms; Peptides; Polyethylene Glycols; Polymers; Proton Magnetic Resonance Spectroscopy; Subcellular Fractions; Taxoids; Vitamin E | 2016 |
Development and evaluation of vitamin E d-α-tocopheryl polyethylene glycol 1000 succinate-mixed polymeric phospholipid micelles of berberine as an anticancer nanopharmaceutical.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Berberine; Caspase 3; Caspase 7; Cell Death; Cell Line, Tumor; Colon; Drug Liberation; Humans; Micelles; Nanoparticles; Phosphatidylethanolamines; Polyethylene Glycols; Solubility; Spheroids, Cellular; Time Factors; Vitamin E | 2016 |
Biocompatible Zr-based nanoscale MOFs coated with modified poly(ε-caprolactone) as anticancer drug carriers.
Topics: Antineoplastic Agents; Caproates; Cell Line, Tumor; Cisplatin; Coated Materials, Biocompatible; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Humans; Hydrophobic and Hydrophilic Interactions; Lactones; Nanoparticles; Paclitaxel; Particle Size; Polyethylene Glycols; Polymers; Vitamin E; Zirconium | 2016 |
Pharmacokinetics, biodistribution, in vitro cytotoxicity and biocompatibility of Vitamin E TPGS coated trans resveratrol liposomes.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Carriers; Liposomes; Male; Nanomedicine; Polyethylene Glycols; Rats; Resveratrol; Stilbenes; Vitamin E | 2016 |
Formulation optimization of Docetaxel loaded self-emulsifying drug delivery system to enhance bioavailability and anti-tumor activity.
Topics: Animals; Antineoplastic Agents; Biological Availability; Breast Neoplasms; Cell Survival; Docetaxel; Drug Compounding; Drug Delivery Systems; Drug Stability; Emulsions; Ethylene Glycols; Female; Humans; Male; MCF-7 Cells; Mice, Inbred BALB C; Polyethylene Glycols; Polymers; Propylene Glycols; Rats; Rats, Sprague-Dawley; Solubility; Taxoids; Vitamin E; Xenograft Model Antitumor Assays | 2016 |
A safe, simple and efficient doxorubicin prodrug hybrid micelle for overcoming tumor multidrug resistance and targeting delivery.
Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Cell Survival; Doxorubicin; Drug Delivery Systems; Drug Liberation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Male; MCF-7 Cells; Mice, Inbred C57BL; Micelles; Neoplasms; Prodrugs; Rats, Sprague-Dawley; Tumor Burden; Vitamin E | 2016 |
The Effect of Surfactant on Paclitaxel Nanocrystals: An In Vitro and In Vivo Study.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Size; Diffusion; Female; Metabolic Clearance Rate; Mice; Mice, Inbred C57BL; Nanocapsules; Neoplasms, Experimental; Organ Specificity; Paclitaxel; Polyethylene Glycols; Surface-Active Agents; Tissue Distribution; Treatment Outcome; Vitamin E | 2016 |
Vitamin E synthetic derivate-TPGS-selectively induces apoptosis in jurkat t cells via oxidative stress signaling pathways: implications for acute lymphoblastic leukemia.
Topics: Apoptosis; DNA Fragmentation; Humans; Jurkat Cells; Oxidative Stress; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Signal Transduction; Vitamin E | 2016 |
TPGS-modified liposomes for the delivery of ginsenoside compound K against non-small cell lung cancer: formulation design and its evaluation in vitro and in vivo.
Topics: A549 Cells; Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Drug Carriers; Ginsenosides; Liposomes; Male; Mice, Nude; Panax; Phospholipids; Phytotherapy; Plant Extracts; Polyethylene Glycols; Vitamin E | 2016 |
Robust aptamer-polydopamine-functionalized M-PLGA-TPGS nanoparticles for targeted delivery of docetaxel and enhanced cervical cancer therapy.
Topics: Animals; Antineoplastic Agents; Aptamers, Nucleotide; Docetaxel; Drug Carriers; Drug Delivery Systems; Female; HeLa Cells; Humans; Indoles; Lactic Acid; Mice, SCID; Nanoparticles; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Taxoids; Uterine Cervical Neoplasms; Vitamin E; Xenograft Model Antitumor Assays | 2016 |
Paclitaxel-Loaded TPGS-b-PCL Nanoparticles: In Vitro Cytotoxicity and Cellular Uptake in MCF-7 and MDA-MB-231 Cells versus mPEG-b-PCL Nanoparticles and Abraxane®.
Topics: Albumin-Bound Paclitaxel; Cytotoxins; Female; Humans; MCF-7 Cells; Nanoparticles; Neoplasms; Paclitaxel; Polyesters; Polyethylene Glycols; Vitamin E | 2016 |
Oral Tocofersolan Corrects or Prevents Vitamin E Deficiency in Children With Chronic Cholestasis.
Topics: Administration, Oral; Child; Child, Preschool; Cholestasis; Chronic Disease; Female; Humans; Infant; Infant, Newborn; Male; Registries; Vitamin E; Vitamin E Deficiency; Vitamins | 2016 |
Novel carvedilol paediatric nanomicelle formulation: in-vitro characterization and in-vivo evaluation.
Topics: Administration, Oral; Animals; Biological Availability; Carbazoles; Carvedilol; Chemistry, Pharmaceutical; Drug Carriers; Male; Micelles; Microscopy, Electron, Transmission; Nanoparticles; Particle Size; Polyethylene Glycols; Polymers; Polyvinyls; Propanolamines; Rats; Rats, Wistar; Solubility; Vitamin E | 2017 |
Enhanced anticancer activity in vitro and in vivo of luteolin incorporated into long-circulating micelles based on DSPE-PEG2000 and TPGS.
Topics: A549 Cells; alpha-Tocopherol; Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Chemistry, Pharmaceutical; Drug Carriers; Drug Delivery Systems; Drug Liberation; Lung Neoplasms; Luteolin; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Micelles; Particle Size; Phosphatidylethanolamines; Polyethylene Glycols; Vitamin E | 2016 |
Vitamin E succinate-conjugated F68 micelles for mitoxantrone delivery in enhancing anticancer activity.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Delayed-Action Preparations; Drug Delivery Systems; Endocytosis; Female; Humans; MCF-7 Cells; Micelles; Mitoxantrone; Poloxamer; Proton Magnetic Resonance Spectroscopy; Spectroscopy, Fourier Transform Infrared; Vitamin E | 2016 |
RGD-TPGS decorated theranostic liposomes for brain targeted delivery.
Topics: Animals; Antineoplastic Agents; Brain; Brain Neoplasms; Docetaxel; Drug Carriers; Drug Delivery Systems; Drug Liberation; Liposomes; Nanoparticles; Quantum Dots; Rats; Rats, Inbred Strains; Reactive Oxygen Species; Taxoids; Theranostic Nanomedicine; Vitamin E | 2016 |
Emodin-Loaded PLGA-TPGS Nanoparticles Combined with Heparin Sodium-Loaded PLGA-TPGS Nanoparticles to Enhance Chemotherapeutic Efficacy Against Liver Cancer.
Topics: Animals; Antimicrobial Cationic Peptides; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Liberation; Emodin; Fluorescent Dyes; Heparin; Humans; Liver Neoplasms; Male; Mice; Nanoparticles; Particle Size; Surface Properties; Vitamin E | 2016 |
Development of a novel l-sulpiride-loaded quaternary microcapsule: Effect of TPGS as an absorption enhancer on physicochemical characterization and oral bioavailability.
Topics: Administration, Oral; Animals; Biological Availability; Capsules; Drug Carriers; Drug Delivery Systems; Male; Polymers; Povidone; Rats; Rats, Sprague-Dawley; Sodium Dodecyl Sulfate; Solubility; Sulpiride; Surface-Active Agents; Tissue Distribution; Vitamin E | 2016 |
Solid lipid nanoparticles co-loaded with doxorubicin and α-tocopherol succinate are effective against drug-resistant cancer cells in monolayer and 3-D spheroid cancer cell models.
Topics: Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Resistance, Neoplasm; Humans; Nanoparticles; Particle Size; Spheroids, Cellular; Vitamin E | 2016 |
Oleanolic acid-loaded PLGA-TPGS nanoparticles combined with heparin sodium-loaded PLGA-TPGS nanoparticles for enhancing chemotherapy to liver cancer.
Topics: Animals; Antineoplastic Agents; Hep G2 Cells; Heparin; Humans; Lactic Acid; Liver Neoplasms; Mice; Nanoparticles; Oleanolic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vitamin E | 2016 |
A cost-effective method to prepare curcumin nanosuspensions with enhanced oral bioavailability.
Topics: Administration, Oral; Animals; Biological Availability; Carbon Dioxide; Curcumin; Drug Stability; Male; Nanostructures; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Suspensions; Vitamin E | 2017 |
Redox-sensitive mPEG-SS-PTX/TPGS mixed micelles: An efficient drug delivery system for overcoming multidrug resistance.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Ethylene Glycols; Humans; MCF-7 Cells; Micelles; Oxidation-Reduction; Paclitaxel; Vitamin E | 2016 |
Physiochemical and cytotoxicity study of TPGS stabilized nanoemulsion designed by ultrasonication method.
Topics: Antineoplastic Agents; Cell Survival; Chemical Phenomena; Drug Carriers; Drug Liberation; Emulsions; Hep G2 Cells; Humans; Nanostructures; Particle Size; Quinine; Sonication; Surface-Active Agents; Vitamin E; Vitamins | 2017 |
Radiolabeling and biological characterization of TPGS-based nanomicelles by means of small animal imaging.
Topics: Animals; Isotope Labeling; Micelles; Molecular Imaging; Nanotechnology; Rats; Rats, Sprague-Dawley; Technetium; Tissue Distribution; Vitamin E | 2017 |
Tyroservatide-TPGS-paclitaxel liposomes: Tyroservatide as a targeting ligand for improving breast cancer treatment.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Cell Line, Tumor; Drug Combinations; Drug Delivery Systems; Female; Humans; Liposomes; Mice; Mice, Nude; Oligopeptides; Paclitaxel; Vitamin E | 2017 |
Improved oral bioavailability and therapeutic efficacy of dabigatran etexilate via Soluplus-TPGS binary mixed micelles system.
Topics: Administration, Oral; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Caco-2 Cells; Dabigatran; Drug Delivery Systems; Fibrinolytic Agents; Humans; Intestinal Absorption; Micelles; Polyethylene Glycols; Polyvinyls; Thrombosis; Vitamin E | 2017 |
Porous mannitol carrier for pulmonary delivery of cyclosporine A nanoparticles.
Topics: Administration, Inhalation; Chemistry, Pharmaceutical; Cyclosporine; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Stability; Drug Storage; Freeze Drying; Hydrophobic and Hydrophilic Interactions; Immunosuppressive Agents; Lecithins; Lung; Mannitol; Nanoparticles; Porosity; Vitamin E | 2017 |
Ascorbyl palmitate/d-α-tocopheryl polyethylene glycol 1000 succinate monoester mixed micelles for prolonged circulation and targeted delivery of compound K for antilung cancer therapy in vitro and in vivo.
Topics: A549 Cells; Animals; Apoptosis; Ascorbic Acid; Cell Cycle; Cell Movement; Drug Delivery Systems; Endocytosis; Ginsenosides; Humans; In Situ Nick-End Labeling; Lung Neoplasms; Mice, Nude; Micelles; Succinates; Tumor Burden; Vitamin E | 2017 |
Hyaluronic acid-modified didecyldimethylammonium bromide/ d-a-tocopheryl polyethylene glycol succinate mixed micelles for delivery of baohuoside I against non-small cell lung cancer: in vitro and in vivo evaluation.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Flavonoids; Humans; Hyaluronic Acid; Inhibitory Concentration 50; Injections, Intravenous; Lung Neoplasms; Male; Mice, Inbred BALB C; Mice, Nude; Micelles; Paclitaxel; Quaternary Ammonium Compounds; Solubility; Surface Properties; Technology, Pharmaceutical; Time Factors; Vitamin E; Xenograft Model Antitumor Assays | 2017 |
D-α-tocopheryl polyethylene glycol 1000 succinate functionalized nanographene oxide for cancer therapy.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Female; Graphite; Humans; Nanoparticles; Oxides; Vitamin E | 2017 |
Mitoxantrone- and Folate-TPGS2k Conjugate Hybrid Micellar Aggregates To Circumvent Toxicity and Enhance Efficiency for Breast Cancer Therapy.
Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Delivery Systems; Drug Liberation; Female; Folic Acid; Humans; Male; MCF-7 Cells; Mice; Mice, Nude; Micelles; Mitoxantrone; Rats; Rats, Sprague-Dawley; Vitamin E | 2017 |
Preparation and in-vitro/in-vivo characterization of trans-resveratrol nanocrystals for oral administration.
Topics: Administration, Oral; Animals; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Survival; Drug Liberation; Drug Stability; Humans; Lecithins; Microscopy, Electron, Scanning; Nanoparticles; Particle Size; Poloxamer; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Vitamin E | 2017 |
Vitamin E Succinate-Grafted-Chitosan Oligosaccharide/RGD-Conjugated TPGS Mixed Micelles Loaded with Paclitaxel for U87MG Tumor Therapy.
Topics: alpha-Tocopherol; Animals; Antineoplastic Agents; Cell Line, Tumor; Chitosan; Drug Carriers; Glioma; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Micelles; Nanoparticles; Oligopeptides; Oligosaccharides; Paclitaxel; Particle Size; Succinates; Vitamin E | 2017 |
Fabrication and in vitro/in vivo evaluation of amorphous andrographolide nanosuspensions stabilized by d-α-tocopheryl polyethylene glycol 1000 succinate/sodium lauryl sulfate.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Biological Transport; Caco-2 Cells; Diterpenes; Humans; Interleukin-1; Male; Mice; Nanoparticles; Nanotechnology; Nitric Oxide; Particle Size; Rats, Sprague-Dawley; Sodium Dodecyl Sulfate; Solubility; Superoxide Dismutase; Suspensions; Time Factors; Tumor Necrosis Factor-alpha; Vitamin E | 2017 |
Improved Bioavailability and Antitumor Effect of Docetaxel by TPGS Modified Proniosomes: In Vitro and In Vivo Evaluations.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Biological Availability; Breast Neoplasms; Caco-2 Cells; Disease Models, Animal; Docetaxel; Drug Carriers; Humans; Liposomes; Mice; Taxoids; Treatment Outcome; Vitamin E | 2017 |
Co-delivery nanoparticles with characteristics of intracellular precision release drugs for overcoming multidrug resistance.
Topics: Alginates; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Chitosan; Doxorubicin; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Resistance, Multiple; Emulsions; Glucuronic Acid; Hexuronic Acids; Humans; Lactic Acid; Mice, Nude; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vincristine; Vitamin E; Xenograft Model Antitumor Assays | 2017 |
Folic acid-functionalized drug delivery platform of resveratrol based on Pluronic 127/D-α-tocopheryl polyethylene glycol 1000 succinate mixed micelles.
Topics: Animals; Cell Line, Tumor; Drug Delivery Systems; Folic Acid; Humans; Magnetic Resonance Spectroscopy; MCF-7 Cells; Micelles; Poloxamer; Polyethylene Glycols; Rats, Sprague-Dawley; Resveratrol; Spectrophotometry, Infrared; Stilbenes; Tissue Distribution; Vitamin E | 2017 |
Structural and Spectroscopic Characterization of TPGS Micelles: Disruptive Role of Cyclodextrins and Kinetic Pathways.
Topics: Cyclodextrins; Micelles; Polyethylene Glycols; Vitamin E | 2017 |
Self-assembled dehydropeptide nano carriers for delivery of ornidazole and curcumin.
Topics: Curcumin; Delayed-Action Preparations; Drug Compounding; Drug Liberation; Hydrophobic and Hydrophilic Interactions; Kinetics; Nanoparticles; Oligopeptides; Ornidazole; Particle Size; Phenylalanine; Vitamin E | 2017 |
Graphene oxide nanosheets and d-α-Tocopheryl polyethylene glycol 1000 succinate (TPGS) doping improves biocompatibility and ultrafiltration in polyethersulfone hollow fiber membranes.
Topics: Biocompatible Materials; Blood Coagulation; Graphite; HEK293 Cells; Hemolysis; Humans; Materials Testing; Membranes, Artificial; Nanostructures; Oxides; Platelet Adhesiveness; Polymers; Porosity; Sulfones; Ultrafiltration; Vitamin E | 2017 |
Topical Coenzyme Q10 demonstrates mitochondrial-mediated neuroprotection in a rodent model of ocular hypertension.
Topics: Animals; Disease Models, Animal; Male; Mitochondria; Neuroprotection; Neuroprotective Agents; Ocular Hypertension; Rats; Retinal Ganglion Cells; Treatment Outcome; Ubiquinone; Vitamin E | 2017 |
Redox-triggered mitoxantrone prodrug micelles for overcoming multidrug-resistant breast cancer.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Drug Delivery Systems; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Micelles; Mitoxantrone; Molecular Structure; Oxidation-Reduction; Prodrugs; Vitamin E | 2018 |
Pluronic F127 and D-α-Tocopheryl Polyethylene Glycol Succinate (TPGS) Mixed Micelles for Targeting Drug Delivery across The Blood Brain Barrier.
Topics: Animals; Biological Transport; Blood-Brain Barrier; Brain; Drug Carriers; Drug Delivery Systems; Immunohistochemistry; Intracellular Space; Micelles; Molecular Targeted Therapy; Optical Imaging; Poloxamer; Rats; Vitamin E | 2017 |
TPGS-Functionalized Polydopamine-Modified Mesoporous Silica as Drug Nanocarriers for Enhanced Lung Cancer Chemotherapy against Multidrug Resistance.
Topics: A549 Cells; Drug Delivery Systems; Humans; Indoles; Lung Neoplasms; Microscopy, Electron, Transmission; Nanoparticles; Photoelectron Spectroscopy; Polyethylene Glycols; Polymers; Silicon Dioxide; Spectroscopy, Fourier Transform Infrared; Vitamin E | 2017 |
Dual roles of TPGS based microemulsion for tacrolimus: Enhancing the percutaneous delivery and anti-psoriatic efficacy.
Topics: Animals; Cell Line; Drug Carriers; Humans; Male; Mice; Mice, Inbred BALB C; Polyethylene Glycols; Psoriasis; Rats, Sprague-Dawley; Skin Absorption; Tacrolimus; Vitamin E | 2017 |
Palatable food self-administration and reinstatement are not affected by dual orexin receptor antagonism.
Topics: Animals; Benzimidazoles; Brain; Conditioning, Operant; Extinction, Psychological; Food; Male; Microinjections; Orexin Receptor Antagonists; Orexin Receptors; Proto-Oncogene Proteins c-fos; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Reinforcement, Psychology; Self Administration; Vitamin E | 2018 |
The antitumor efficacy of docetaxel is enhanced by encapsulation in novel amphiphilic polymer cholesterol-coupled tocopheryl polyethylene glycol 1000 succinate micelles.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chemistry, Pharmaceutical; Cholesterol; Docetaxel; Mice; Micelles; Particle Size; Sarcoma, Experimental; Taxoids; Vitamin E; Xenograft Model Antitumor Assays | 2017 |
Glycyrrhetinic acid-modified TPGS polymeric micelles for hepatocellular carcinoma-targeted therapy.
Topics: Carcinoma, Hepatocellular; Drug Carriers; Etoposide; Glycyrrhetinic Acid; Humans; Micelles; Vitamin E | 2017 |
Synergistic apoptotic effects of apigenin TPGS liposomes and tyroservatide: implications for effective treatment of lung cancer.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apigenin; Cell Line, Tumor; Drug Combinations; Humans; Liposomes; Lung Neoplasms; Male; Mice, Nude; Oligopeptides; Vitamin E; Xenograft Model Antitumor Assays | 2017 |
Phloretin-loaded fast dissolving nanofibers for the locoregional therapy of oral squamous cell carcinoma.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Drug Carriers; Humans; Mouth Neoplasms; Nanofibers; Phloretin; Polyvinyl Alcohol; Solubility; Vitamin E | 2017 |
Effect of surfactants and drug load on physico-mechanical and dissolution properties of nanocrystalline tadalafil-loaded oral films.
Topics: Administration, Oral; Drug Delivery Systems; Drug Liberation; Glycerol; Hypromellose Derivatives; Microscopy, Electron, Scanning; Nanoparticles; Phosphodiesterase 5 Inhibitors; Poloxamer; Solubility; Stress, Mechanical; Surface-Active Agents; Tadalafil; Tensile Strength; Vitamin E | 2017 |
Mixed micelles based on a pH-sensitive prodrug and TPGS for enhancing drug efficacy against multidrug-resistant cancer cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Hydrogen-Ion Concentration; MCF-7 Cells; Micelles; Polyethylene Glycols; Vitamin E | 2017 |
Gel-like TPGS-Based Microemulsions for Imiquimod Dermal Delivery: Role of Mesostructure on the Uptake and Distribution into the Skin.
Topics: Adjuvants, Immunologic; Administration, Cutaneous; Aminoquinolines; Animals; Drug Carriers; Emulsions; Ethylene Glycols; Imiquimod; Oleic Acid; Scattering, Radiation; Skin; Skin Absorption; Swine; Tissue Distribution; Viscosity; Vitamin E | 2017 |
Enhanced transmucosal delivery of itraconazole by thiolated d-ɑ-tocopheryl poly(ethylene glycol) 1000 succinate micelles for the treatment of Candida albicans.
Topics: Antifungal Agents; Candida albicans; Candidiasis; Humans; Itraconazole; Micelles; Mouth Mucosa; Nanoparticles; Polymers; Vitamin E | 2017 |
[Preparation and in vitro evaluation of ampelopsin-loaded nanomicelles].
Topics: Antineoplastic Agents; Drug Carriers; Drug Delivery Systems; Flavonoids; Humans; MCF-7 Cells; Nanostructures; Particle Size; Poloxamer; Solubility; Vitamin E | 2016 |
Novel freeze-dried DDA and TPGS liposomes are suitable for nasal delivery of vaccine.
Topics: Administration, Intranasal; Animals; Antigens; Cattle; Cell Line; Cell Survival; Female; Freeze Drying; Humans; Immunoglobulin G; Liposomes; Mice, Inbred C57BL; Nasal Mucosa; Ovalbumin; Quaternary Ammonium Compounds; Vaccines; Vitamin E | 2017 |
Concomitant solubility-permeability increase: Vitamin E TPGS vs. amorphous solid dispersion as oral delivery systems for etoposide.
Topics: Administration, Oral; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Delivery Systems; Etoposide; Male; Permeability; Rats; Rats, Wistar; Solubility; Surface-Active Agents; Vitamin E | 2017 |
Apolipoproteins adsorption and brain-targeting evaluation of baicalin nanocrystals modified by combination of Tween80 and TPGS.
Topics: Adsorption; Animals; Apolipoproteins; Area Under Curve; Blood-Brain Barrier; Brain; Flavonoids; Humans; Male; Microscopy, Electron, Transmission; Nanoparticles; Particle Size; Polysorbates; Rats, Wistar; Suspensions; Vitamin E | 2017 |
Nebulized coenzyme Q
Topics: A549 Cells; Aerosols; Antioxidants; Biological Transport; Calibration; Cell Survival; Chemistry, Pharmaceutical; Drug Delivery Systems; Drug Liberation; Drug Stability; Humans; Lecithins; Lung; Nanoparticles; Nebulizers and Vaporizers; Particle Size; Stearates; Surface Properties; Ubiquinone; Viscosity; Vitamin E | 2018 |
Comparison of the Local Tolerability to 5 Long-acting Drug Nanosuspensions with Different Stabilizing Excipients, Following a Single Intramuscular Administration in the Rat.
Topics: Animals; Antiviral Agents; Excipients; Injections, Intramuscular; Male; Nanoparticles; Poloxamer; Polysorbates; Rats; Rats, Sprague-Dawley; Vitamin E | 2018 |
Process optimization and in vivo performance of docetaxel loaded PHBV-TPGS therapeutic vesicles: A synergistic approach.
Topics: Animals; Antineoplastic Agents; Biocompatible Materials; Calorimetry, Differential Scanning; Cell Survival; Chromatography, High Pressure Liquid; Colloids; Disease Models, Animal; Docetaxel; Drug Carriers; Drug Compounding; Drug Delivery Systems; Drug Liberation; Humans; Hydrogen-Ion Concentration; Mice; Nanoparticles; Particle Size; Polyesters; Spectroscopy, Fourier Transform Infrared; Taxoids; Vitamin E; X-Ray Diffraction; Xenograft Model Antitumor Assays | 2018 |
Near-infrared light-responsive nanoparticles for improved anticancer efficacy through synergistic chemo-photothermal therapy.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Combined Modality Therapy; Doxorubicin; Drug Synergism; Female; Hyperthermia, Induced; Indocyanine Green; Mice; Nanoparticles; Polyethylene Glycols; Vitamin E | 2018 |
Development and in-vitro characterization of nanoemulsions loaded with paclitaxel/γ-tocotrienol lipid conjugates.
Topics: Antineoplastic Agents; Cell Line, Tumor; Chemistry, Pharmaceutical; Emulsions; Humans; Lipids; Nanoparticles; Paclitaxel; Polyethylene Glycols; Tocotrienols; Vitamin E | 2018 |
mPEG-PLA/TPGS mixed micelles via intranasal administration improved the bioavailability of lamotrigine in the hippocampus.
Topics: Administration, Intranasal; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Drug Delivery Systems; Hippocampus; Lamotrigine; Micelles; Particle Size; Polyesters; Polyethylene Glycols; Rats, Sprague-Dawley; Triazines; Vitamin E | 2017 |
Optimization of Weight Ratio for DSPE-PEG/TPGS Hybrid Micelles to Improve Drug Retention and Tumor Penetration.
Topics: Amsacrine; Animals; Antineoplastic Agents; Cell Culture Techniques; Cell Survival; Delayed-Action Preparations; Drug Carriers; Drug Liberation; Drug Stability; Half-Life; Humans; Male; MCF-7 Cells; Micelles; Nanoparticles; Particle Size; Permeability; Phosphatidylethanolamines; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Surface Properties; Vitamin E | 2018 |
Transferrin and tocopheryl-polyethylene glycol-succinate dual ligands decorated, cisplatin loaded nano-sized system for the treatment of lung cancer.
Topics: Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cisplatin; Drug Liberation; Endocytosis; Humans; Ligands; Lung Neoplasms; Mice, Nude; Nanoparticles; Palmitic Acid; Particle Size; Polyesters; Proton Magnetic Resonance Spectroscopy; Static Electricity; Tissue Distribution; Transferrin; Vitamin E | 2018 |
Combination of Oxaliplatin and Vit.E-TPGS in Lipid Nanosystem for Enhanced Therapeutic Efficacy in Colon Cancers.
Topics: Antineoplastic Agents; Apoptosis; Colonic Neoplasms; Drug Carriers; Drug Compounding; Drug Screening Assays, Antitumor; HT29 Cells; Humans; Inhibitory Concentration 50; Lipids; Nanoparticles; Oxaliplatin; Vitamin E | 2018 |
Micelle System Based on Molecular Economy Principle for Overcoming Multidrug Resistance and Inhibiting Metastasis.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Delayed-Action Preparations; Doxorubicin; Drug Carriers; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Female; Humans; Hydrazines; Indazoles; Lung; Lung Neoplasms; MCF-7 Cells; Mice; Mice, Inbred BALB C; Micelles; Nanomedicine; Nitric Oxide; Rats; Rats, Sprague-Dawley; Tissue Distribution; Treatment Outcome; Vitamin E; Xenograft Model Antitumor Assays | 2018 |
Using PVA and TPGS as combined emulsifier in nanoprecipitation method improves characteristics and anticancer activity of ibuprofen loaded PLGA nanoparticles.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Breast Neoplasms; Caco-2 Cells; Chemistry, Pharmaceutical; Colorectal Neoplasms; Drug Liberation; Emulsifying Agents; Female; Humans; Ibuprofen; Lactic Acid; MCF-7 Cells; Mice; Microscopy, Electron, Transmission; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyvinyl Alcohol; Vitamin E | 2017 |
Redox-responsive F127-folate/F127-disulfide bond-d-α-tocopheryl polyethylene glycol 1000 succinate/P123 mixed micelles loaded with paclitaxel for the reversal of multidrug resistance in tumors.
Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; Disulfides; Drug Liberation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Endocytosis; Folic Acid; Humans; Inhibitory Concentration 50; MCF-7 Cells; Micelles; Mitochondria; Neoplasms; Oxidation-Reduction; Paclitaxel; Poloxalene; Poloxamer; Reactive Oxygen Species; Vitamin E | 2018 |
Functionalization of nanodiamond with vitamin E TPGS to facilitate oral absorption of curcumin.
Topics: Administration, Oral; Animals; Area Under Curve; Biological Availability; Crystallography, X-Ray; Curcumin; Drug Carriers; Drug Compounding; Drug Stability; Endocytosis; Intestinal Absorption; Male; Microscopy, Electron, Transmission; Models, Statistical; Nanodiamonds; Nanomedicine; Rats, Wistar; Solubility; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Surface Properties; Technology, Pharmaceutical; Vitamin E | 2018 |
Curcumin-Loaded TPGS/F127/P123 Mixed Polymeric Micelles for Cervical Cancer Therapy: Formulation, Characterization, and
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Curcumin; Drug Carriers; Female; HeLa Cells; Humans; Materials Testing; Mice; Micelles; NIH 3T3 Cells; Polyethylenes; Polypropylenes; Uterine Cervical Neoplasms; Vitamin E | 2017 |
Fabrication of surfactant-stabilized nanosuspension of naringenin to surpass its poor physiochemical properties and low oral bioavailability.
Topics: Administration, Oral; Animals; Biological Availability; Drug Delivery Systems; Drug Stability; Flavanones; Male; Nanoparticles; Nanostructures; Particle Size; Polyethylene Glycols; Rats, Sprague-Dawley; Solubility; Surface-Active Agents; Suspensions; Vitamin E | 2018 |
A multifunctional nanoplatform for cancer chemo-photothermal synergistic therapy and overcoming multidrug resistance.
Topics: Animals; Antineoplastic Agents; Docetaxel; Dopamine; Drug Liberation; Drug Resistance, Neoplasm; Female; Humans; Lactic Acid; Mammary Neoplasms, Experimental; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Phototherapy; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Taxoids; Vitamin E | 2018 |
TPGS functionalized mesoporous silica nanoparticles for anticancer drug delivery to overcome multidrug resistance.
Topics: Animals; Antineoplastic Agents; Apoptosis; Biocompatible Materials; Breast Neoplasms; Cell Line, Tumor; Doxorubicin; Drug Carriers; Drug Liberation; Drug Resistance, Neoplasm; Female; Humans; MCF-7 Cells; Mice; Microscopy, Confocal; Nanoparticles; Porosity; Silicon Dioxide; Tissue Distribution; Vitamin E | 2018 |
Barbaloin loaded polydopamine-polylactide-TPGS (PLA-TPGS) nanoparticles against gastric cancer as a targeted drug delivery system: Studies in vitro and in vivo.
Topics: Animals; Anthracenes; Antineoplastic Agents, Phytogenic; Biological Transport; Cell Line, Tumor; Cell Proliferation; Drug Compounding; Drug Delivery Systems; Epithelial Cells; Galactosamine; Humans; Indoles; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Polyesters; Polymers; Stomach Neoplasms; Treatment Outcome; Tumor Burden; Vitamin E; Xenograft Model Antitumor Assays | 2018 |
Assessment of interactions of efavirenz solid drug nanoparticles with human immunological and haematological systems.
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cell Line, Tumor; Clinical Trials as Topic; Complement Activation; Cyclopropanes; Drug Carriers; Drug Compounding; Drug Evaluation, Preclinical; Epithelial Cells; Erythrocytes; Hemolysis; Humans; Killer Cells, Natural; Limulus Test; Lipopolysaccharides; Nanoparticles; Platelet Activation; Platelet Aggregation; Polyvinyl Alcohol; Primary Cell Culture; T-Lymphocytes; Vitamin E | 2018 |
Surface modification of paclitaxel-loaded liposomes using d-α-tocopheryl polyethylene glycol 1000 succinate: Enhanced cellular uptake and cytotoxicity in multidrug resistant breast cancer cells.
Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Cell Survival; Drug Liberation; Drug Resistance, Neoplasm; Female; Humans; Liposomes; MCF-7 Cells; Microscopy, Confocal; Paclitaxel; Particle Size; Polysorbates; Solubility; Vitamin E | 2018 |
Co-delivery of doxorubicin and imatinib by pH sensitive cleavable PEGylated nanoliposomes with folate-mediated targeting to overcome multidrug resistance.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Survival; Doxorubicin; Drug Liberation; Drug Resistance, Neoplasm; Drug Stability; Female; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Hydrogen-Ion Concentration; Imatinib Mesylate; Liposomes; MCF-7 Cells; Mice, Inbred BALB C; Mice, Nude; Vitamin E | 2018 |
[Tissue distribution of TPGS modified artesunate liposome and its metabolites in rats].
Topics: Animals; Artesunate; Chromatography, Liquid; Liposomes; Rats; Tandem Mass Spectrometry; Tissue Distribution; Vitamin E | 2018 |
Impact of molecular rearrangement of amphiphilic stabilizers on physical stability of itraconazole nanoparticles prepared by flash nanoprecipitation.
Topics: Antifungal Agents; Chemical Precipitation; Drug Compounding; Drug Stability; Itraconazole; Microscopy, Atomic Force; Nanoparticles; Photoelectron Spectroscopy; Polyethylene Glycols; Vitamin E | 2018 |
Cryoprotectant choice and analyses of freeze-drying drug suspension of nanoparticles with functional stabilisers.
Topics: Antioxidants; Cryoprotective Agents; Drug Stability; Excipients; Folic Acid; Freeze Drying; Nanoparticles; Particle Size; Phosphatidylethanolamines; Polyethylene Glycols; Quercetin; Resveratrol; Solubility; Stilbenes; Suspensions; Vitamin E | 2018 |
Vitamin E TPGS Emulsified Vinorelbine Bitartrate Loaded Solid Lipid Nanoparticles (SLN): Formulation Development, Optimization and In vitro Characterization.
Topics: Antineoplastic Agents, Phytogenic; Cell Survival; Chemistry, Pharmaceutical; Drug Carriers; Drug Liberation; Drug Stability; Emulsions; Glycerides; Humans; MCF-7 Cells; Nanoparticles; Vinblastine; Vinorelbine; Vitamin E; Vitamins | 2018 |
Improving the biopharmaceutical attributes of mangiferin using vitamin E-TPGS co-loaded self-assembled phosholipidic nano-mixed micellar systems.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Survival; Drug Liberation; Female; Humans; Jejunum; Micelles; Nanostructures; Phospholipids; Rats, Sprague-Dawley; Solubility; Vitamin E; Xanthones | 2018 |
Reversion of Multidrug Resistance by Co-Encapsulation of Doxorubicin and Metformin in Poly(lactide-co-glycolide)-d-α-tocopheryl Polyethylene Glycol 1000 Succinate Nanoparticles.
Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Breast Neoplasms; Doxorubicin; Drug Compounding; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; MCF-7 Cells; Metformin; Nanoparticles; Polylactic Acid-Polyglycolic Acid Copolymer; Vitamin E | 2018 |
Self-controlled release of Oxaliplatin prodrug from d-α-tocopheryl polyethylene glycol 1000 succinate (TPGS) functionalized mesoporous silica nanoparticles for cancer therapy.
Topics: A549 Cells; Antineoplastic Agents; Biological Transport; Cell Survival; Delayed-Action Preparations; Drug Carriers; Drug Liberation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorescein-5-isothiocyanate; Humans; Hydrogen-Ion Concentration; Nanoparticles; Organoplatinum Compounds; Oxaliplatin; Particle Size; Polyethylene Glycols; Porosity; Prodrugs; Silicon Dioxide; Succinates; Surface Properties; Vitamin E | 2018 |
Extracellular matrix-coated polyethersulfone-TPGS hollow fiber membranes showing improved biocompatibility and uremic toxins removal for bioartificial kidney application.
Topics: Cell Proliferation; Coated Materials, Biocompatible; Extracellular Matrix; HEK293 Cells; Hemolysis; Humans; Kidney; Membranes, Artificial; Microscopy, Confocal; Microscopy, Electron, Scanning; Platelet Adhesiveness; Polymers; Renal Dialysis; Sulfones; Uremia; Vitamin E | 2018 |
Star-shaped polymer of β‑cyclodextrin-g-vitamin E TPGS for doxorubicin delivery and multidrug resistance inhibition.
Topics: Animals; Antibiotics, Antineoplastic; beta-Cyclodextrins; Cell Proliferation; Cell Survival; Doxorubicin; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; Liver Neoplasms; MCF-7 Cells; Mice; Mice, Inbred Strains; Molecular Structure; Particle Size; Polyethylene Glycols; Polymers; Succinates; Surface Properties; Tumor Cells, Cultured; Vitamin E | 2018 |
Preparation, characterization, and pharmacokinetics study of a novel genistein-loaded mixed micelles system.
Topics: Administration, Oral; Animals; Biological Availability; Caco-2 Cells; Cell Line, Tumor; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Drug Liberation; Genistein; Humans; Hydrophobic and Hydrophilic Interactions; Male; Micelles; Particle Size; Polyethylene Glycols; Polyvinyls; Rats; Rats, Sprague-Dawley; Solubility; Vitamin E | 2018 |
Nrp-1 receptor targeting peptide-functionalized TPGS micellar nanosystems to deliver 10-hydroxycampothecin for enhanced cancer chemotherapy.
Topics: A549 Cells; Apoptosis; Camptothecin; Cell Nucleus; DNA Topoisomerases, Type I; Drug Carriers; Drug Synergism; Hep G2 Cells; Humans; Inhibitory Concentration 50; MCF-7 Cells; Micelles; Mitochondria; Nanoparticles; Neoplasms; Neuropilin-1; Peptides; Polymers; Reactive Oxygen Species; Topoisomerase I Inhibitors; Vitamin E | 2018 |
The characterization, pharmacokinetic, and tissue distribution studies of TPGS-modified artesunate liposome in rats.
Topics: Animals; Artemisinins; Artesunate; Liposomes; Male; Mice; Mice, Inbred BALB C; Particle Size; Rats; Rats, Wistar; Tissue Distribution; Vitamin E | 2018 |
N-acetylaminogalactosyl-decorated biodegradable PLGA-TPGS copolymer nanoparticles containing emodin for the active targeting therapy of liver cancer.
Topics: Apoptosis; Biological Transport; Drug Carriers; Emodin; Galactose; Hep G2 Cells; Humans; Liver Neoplasms; Molecular Targeted Therapy; Nanoparticles; Polylactic Acid-Polyglycolic Acid Copolymer; Vitamin E | 2018 |
Augmented anticancer activity of naringenin-loaded TPGS polymeric nanosuspension for drug resistive MCF-7 human breast cancer cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Survival; Drug Resistance, Neoplasm; Flavanones; Humans; Liver; MCF-7 Cells; Membrane Potential, Mitochondrial; Mice; Reactive Oxygen Species; Suspensions; Vitamin E | 2018 |
Lyophilized tablets for focal delivery of fluconazole and itraconazole through vaginal mucosa, rational design and in vitro evaluation.
Topics: Antifungal Agents; Drug Design; Drug Liberation; Female; Fluconazole; Freeze Drying; Humans; Itraconazole; Liposomes; Mucous Membrane; Tablets; Vagina; Vitamin E | 2018 |
Efficacy of two vitamin E formulations in patients with abetalipoproteinemia and chylomicron retention disease.
Topics: Abetalipoproteinemia; Adult; alpha-Tocopherol; Biological Availability; Case-Control Studies; Drug Compounding; Drug Storage; Female; Humans; Hypobetalipoproteinemias; Intestinal Absorption; Malabsorption Syndromes; Male; Middle Aged; Safety; Vitamin E | 2018 |
Triphenylphosphonium and D-α-tocopheryl polyethylene glycol 1000 succinate-modified, tanshinone IIA-loaded lipid-polymeric nanocarriers for the targeted therapy of myocardial infarction.
Topics: Abietanes; Animals; Cell Death; Cell Survival; Drug Carriers; Drug Liberation; Endocytosis; Lipids; Molecular Targeted Therapy; Myocardial Infarction; Nanoparticles; Onium Compounds; Organophosphorus Compounds; Particle Size; Proton Magnetic Resonance Spectroscopy; Rats, Sprague-Dawley; Static Electricity; Tissue Distribution; Vitamin E | 2018 |
TPGS-functionalized and ortho ester-crosslinked dextran nanogels for enhanced cytotoxicity on multidrug resistant tumor cells.
Topics: Adenosine Triphosphate; Anhydrides; Antibiotics, Antineoplastic; Cell Survival; Dextrans; Doxorubicin; Drug Liberation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Esters; Gels; Humans; Hydrogen-Ion Concentration; MCF-7 Cells; Membrane Potential, Mitochondrial; Nanostructures; Vitamin E | 2018 |
Reduction-sensitive mixed micelles for selective intracellular drug delivery to tumor cells and reversal of multidrug resistance.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Delivery Systems; Drug Resistance, Neoplasm; Humans; Hyaluronic Acid; Lung Neoplasms; Mice; Micelles; Polyesters; Rats, Sprague-Dawley; Vitamin E | 2018 |
Fabrication of TPGS-Stabilized Liposome-PLGA Hybrid Nanoparticle Via a New Modified Nanoprecipitation Approach: In Vitro and In Vivo Evaluation.
Topics: Animals; Atherosclerosis; Drug Carriers; Drug Liberation; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liposomes; Mice; Nanoparticles; Oxidative Stress; Particle Size; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits; RAW 264.7 Cells; Simvastatin; Surface Properties; Vitamin E | 2018 |
Conjugation of vitamin E-TPGS and guar gum to carry borneol for enhancing blood-brain barrier permeability.
Topics: 3T3 Cells; Animals; Biological Availability; Blood-Brain Barrier; Camphanes; Cell Survival; Central Nervous System Agents; Drug Delivery Systems; Galactans; Hemolysis; Humans; Mannans; Mice; Micelles; Nanocapsules; Permeability; Plant Gums; Solubility; Succinic Acid; Vitamin E | 2018 |
Investigations on the interactions between curcumin loaded vitamin E TPGS coated nanodiamond and Caco-2 cell monolayer.
Topics: Antioxidants; Biological Transport; Caco-2 Cells; Curcumin; Drug Carriers; Humans; Intestinal Absorption; Nanodiamonds; Vitamin E; Vitamins | 2018 |
Paclitaxel-loaded TPGS enriched self-emulsifying carrier causes apoptosis by modulating survivin expression and inhibits tumour growth in syngeneic mammary tumours.
Topics: Animals; Apoptosis; Drug Delivery Systems; Emulsions; Female; Humans; Isografts; Mammary Neoplasms, Experimental; MCF-7 Cells; Micelles; Neoplasm Transplantation; Paclitaxel; Rats; Rats, Sprague-Dawley; Vitamin E | 2018 |
A pH-sensitive prodrug strategy to co-deliver DOX and TOS in TPGS nanomicelles for tumor therapy.
Topics: Adenocarcinoma; alpha-Tocopherol; Animals; Antibiotics, Antineoplastic; Breast Neoplasms; Cell Line, Tumor; Doxorubicin; Drug Carriers; Female; Heart; Humans; Hydrogen-Ion Concentration; Kidney; Liver; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Micelles; Nanoparticles; Prodrugs; Tumor Burden; Vitamin E; Xenograft Model Antitumor Assays | 2019 |
Trastuzumab decorated TPGS-g-chitosan nanoparticles for targeted breast cancer therapy.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Biological Availability; Breast Neoplasms; Cell Line, Tumor; Chitosan; Docetaxel; Drug Carriers; Female; Glycoconjugates; Humans; Kidney; Liver; Lung; Molecular Targeted Therapy; Nanoparticles; Rats; Receptor, ErbB-2; Trastuzumab; Tumor Burden; Vitamin E; Xenograft Model Antitumor Assays | 2019 |
TPGS modified nanoliposomes as an effective ocular delivery system to treat glaucoma.
Topics: Animals; Carbonic Anhydrase Inhibitors; Cell Line; Chemistry, Pharmaceutical; Cornea; Delayed-Action Preparations; Drug Delivery Systems; Glaucoma; Intraocular Pressure; Liposomes; Male; Mice; Nanoparticles; Particle Size; Permeability; Rabbits; Sulfonamides; Thiazines; Vitamin E | 2018 |
Overcoming the Bile Salt-Mediated Formation of Nanocolloids That Inhibit Oral Absorption of VX-985.
Topics: Administration, Oral; Animals; Antiviral Agents; Biological Availability; Colloids; Drug Carriers; Hepacivirus; Hepatitis C; Humans; Intestinal Absorption; Protease Inhibitors; Rats; Solubility; Spiro Compounds; Taurocholic Acid; Vitamin E | 2019 |
Codelivery of doxorubicin and elacridar to target both liver cancer cells and stem cells by polylactide-co-glycolide/d-alpha-tocopherol polyethylene glycol 1000 succinate nanoparticles.
Topics: Acridines; Animals; Carcinoma, Hepatocellular; Cell Death; Doxorubicin; Drug Delivery Systems; Drug Synergism; Endocytosis; Hep G2 Cells; Humans; Liver Neoplasms; Male; Mice, Nude; Nanoparticles; Neoplastic Stem Cells; Polyesters; Polyethylene Glycols; Rats, Sprague-Dawley; Stem Cell Transplantation; Stem Cells; Subcutaneous Tissue; Tetrahydroisoquinolines; Tissue Distribution; Tumor Stem Cell Assay; Vitamin E | 2018 |
Synergistic effects of VE-TPGS and riboflavin in crosslinking of dentine.
Topics: Collagen; Dentin; Humans; Riboflavin; Vitamin E | 2019 |
Co-delivery of paclitaxel and doxorubicin using mixed micelles based on the redox sensitive prodrugs.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Disulfides; Doxorubicin; Drug Delivery Systems; Drug Liberation; Female; Melanoma, Experimental; Mice; Micelles; Oxidation-Reduction; Paclitaxel; Prodrugs; Propionates; Tumor Burden; Vitamin E | 2019 |
Bufalin-loaded vitamin E succinate-grafted-chitosan oligosaccharide/RGD conjugated TPGS mixed micelles demonstrated improved antitumor activity against drug-resistant colon cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bufanolides; Chitosan; Colonic Neoplasms; Doxorubicin; Drug Resistance, Neoplasm; HCT116 Cells; Humans; Mice, Nude; Micelles; Oligopeptides; Oligosaccharides; Rhodamine 123; Tumor Burden; Vitamin E | 2018 |
Preparation and
Topics: Animals; Biological Availability; Caproates; Catechols; Drug Carriers; Drug Delivery Systems; Fatty Alcohols; Lactones; Male; Micelles; Particle Size; Polyethylene Glycols; Polymers; Rats; Rats, Sprague-Dawley; Solubility; Vitamin E | 2020 |
A personalized and long-acting local therapeutic platform combining photothermal therapy and chemotherapy for the treatment of multidrug-resistant colon tumor.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Combined Modality Therapy; Drug Liberation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Elastic Modulus; Gold; Humans; Hydrogels; Hyperthermia, Induced; Inhibitory Concentration 50; Male; Mice, Nude; Micelles; Nanoparticles; Nanotubes; Neoplasm Recurrence, Local; Paclitaxel; Phototherapy; Polyethylene Glycols; Temperature; Time Factors; Vitamin E | 2018 |
Optimized vinpocetine-loaded vitamin E D-α-tocopherol polyethylene glycol 1000 succinate-alpha lipoic acid micelles as a potential transdermal drug delivery system: in vitro and ex vivo studies.
Topics: Administration, Cutaneous; Animals; Biological Availability; Drug Delivery Systems; Fluorescence; Humans; Micelles; Particle Size; Rats; Skin; Skin Absorption; Solubility; Thioctic Acid; Vinca Alkaloids; Vitamin E | 2019 |
Integrating the drug, disulfiram into the vitamin E-TPGS-modified PEGylated nanostructured lipid carriers to synergize its repurposing for anti-cancer therapy of solid tumors.
Topics: Animals; Antineoplastic Agents; Blood Proteins; Cell Line, Tumor; Disulfiram; Drug Carriers; Drug Liberation; Drug Repositioning; Drug Synergism; Female; Humans; Lipids; Mice, Inbred BALB C; Nanostructures; Neoplasms; Polyethylene Glycols; Rats, Sprague-Dawley; Vitamin E | 2019 |
Enhanced intestinal absorption of asenapine maleate by fabricating solid lipid nanoparticles using TPGS: elucidation of transport mechanism, permeability across Caco-2 cell line and in vivo pharmacokinetic studies.
Topics: Animals; Biological Availability; Biological Transport; Caco-2 Cells; Dibenzocycloheptenes; Drug Carriers; Drug Liberation; Heterocyclic Compounds, 4 or More Rings; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Lipids; Nanoparticles; Particle Size; Permeability; Rats; Vitamin E | 2019 |
Preparation and Characterization of Syringic Acid-Loaded TPGS Liposome with Enhanced Oral Bioavailability and In Vivo Antioxidant Efficiency.
Topics: Administration, Oral; Animals; Antioxidants; Biological Availability; Carbon Tetrachloride Poisoning; Gallic Acid; Half-Life; Liposomes; Male; Mice; Nanoparticles; Particle Size; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Solubility; Tissue Distribution; Vitamin E | 2019 |
Antifungal efficacy of Itraconazole loaded PLGA-nanoparticles stabilized by vitamin-E TPGS: In vitro and ex vivo studies.
Topics: Antifungal Agents; Candida albicans; Chemical Precipitation; Desiccation; Drug Liberation; Freeze Drying; Itraconazole; Nanoparticles; Particle Size; Solubility; Vitamin E; X-Ray Diffraction | 2019 |
Tocophersolan stabilized lipid nanocapsules with high drug loading to improve the permeability and oral bioavailability of curcumin.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Area Under Curve; Biological Availability; Caco-2 Cells; Chemistry, Pharmaceutical; Curcumin; Drug Carriers; Excipients; Humans; Intestinal Absorption; Lipids; Male; Nanocapsules; Particle Size; Permeability; Rats; Rats, Sprague-Dawley; Vitamin E | 2019 |
Combined administration of PTX and S-HM-3 in TPGS/Solutol micelle system for oncotarget therapy.
Topics: Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Movement; Drug Carriers; Female; Humans; Inhibitory Concentration 50; Male; Mice, Inbred BALB C; Mice, Nude; Micelles; Neoplasms; Paclitaxel; Polyethylene Glycols; Stearic Acids; Tissue Distribution; Tumor Burden; Vitamin E; Whole Body Imaging | 2019 |
Dual-functionalized liposome by co-delivery of paclitaxel with sorafenib for synergistic antitumor efficacy and reversion of multidrug resistance.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Female; Humans; Hyaluronic Acid; Liposomes; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Paclitaxel; Polyethylene Glycols; Polymers; Rats; Sorafenib; Vitamin E | 2019 |
Characterization, optimization, and in vitro evaluation of Technetium-99m-labeled niosomes.
Topics: Animals; Carbon-13 Magnetic Resonance Spectroscopy; Humans; Hydrogen-Ion Concentration; Liposomes; Particle Size; Pentetic Acid; Proton Magnetic Resonance Spectroscopy; Radiopharmaceuticals; Spectroscopy, Fourier Transform Infrared; Static Electricity; Surface-Active Agents; Technetium; Time Factors; Tissue Distribution; Vitamin E | 2019 |
D-α-tocopherol polyethylene glycol 1000 succinate-modified liposomes with an siRNA corona confer enhanced cellular uptake and targeted delivery of doxorubicin via tumor priming.
Topics: Animals; Cell Death; Cell Line, Tumor; Cell Proliferation; Doxorubicin; Drug Liberation; Endocytosis; Female; Humans; Kinetics; Mice, Inbred BALB C; Micelles; Neoplasms; Particle Size; Polyethylene Glycols; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering; Spheroids, Cellular; Tissue Distribution; Vitamin E | 2019 |
Preparation, in vitro and in vivo evaluation of isoliquiritigenin-loaded TPGS modified proliposomes.
Topics: Administration, Oral; Animals; Chalcones; Drug Compounding; Drug Liberation; Drug Stability; Liposomes; Liver; Mice, Inbred ICR; Particle Size; Rats, Sprague-Dawley; Solubility; Tissue Distribution; Vitamin E | 2019 |
Synthetic chemistry in water: applications to peptide synthesis and nitro-group reductions.
Topics: Amides; Catalysis; Chemistry Techniques, Synthetic; Green Chemistry Technology; Humans; Hydrogen-Ion Concentration; Kinetics; Micelles; Oxidation-Reduction; Peptides; Polyethylene Glycols; Surface-Active Agents; Temperature; Vitamin E; Water | 2019 |
The roles of a surfactant in zein-HPMC blend solid dispersions for improving drug delivery.
Topics: Crystallization; Drug Liberation; Hydrophobic and Hydrophilic Interactions; Hypromellose Derivatives; Paclitaxel; Surface-Active Agents; Vitamin E; Wettability; Zein | 2019 |
Tocopherol polyethylene glycol succinate-modified hollow silver nanoparticles for combating bacteria-resistance.
Topics: Animals; Biological Transport; Cell Line; Drug Carriers; Drug Resistance, Bacterial; Humans; Metal Nanoparticles; Mice; Particle Size; Silver; Tigecycline; Vitamin E | 2019 |
Enhanced efficacy of baicalin-loaded TPGS polymeric micelles against periodontitis.
Topics: Animals; Apoptosis; Disease Models, Animal; Fibroblasts; Flavonoids; Gingiva; Interleukin-1beta; Lipopolysaccharides; Male; Micelles; NF-kappa B; Periodontitis; Rats; Tumor Necrosis Factor-alpha; Vitamin E; X-Ray Diffraction; X-Ray Microtomography | 2019 |
Improving lung cancer treatment: Hyaluronic acid‑modified and glutathione‑responsive amphiphilic TPGS‑doxorubicin prodrug‑entrapped nanoparticles.
Topics: A549 Cells; Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Doxorubicin; Female; Glutathione; Humans; Hyaluronic Acid; Lung Neoplasms; Mice; Nanoparticles; Particle Size; Prodrugs; Theranostic Nanomedicine; Vitamin E; Xenograft Model Antitumor Assays | 2019 |
Targeted co-delivery of the aldose reductase inhibitor epalrestat and chemotherapeutic doxorubicin via a redox-sensitive prodrug approach promotes synergistic tumor suppression.
Topics: Aldehyde Reductase; Animals; Antineoplastic Agents; Doxorubicin; Drug Carriers; Drug Liberation; Drug Synergism; Enzyme Inhibitors; Female; Humans; Intracellular Space; Mice; Micelles; Oxidation-Reduction; Prodrugs; Rhodanine; Thiazolidines; Tissue Distribution; Vitamin B 6; Vitamin E | 2019 |
The characterisation, pharmacokinetic and tissue distribution studies of TPGS modified myricetrin mixed micelles in rats.
Topics: Animals; Antioxidants; Biological Availability; Drug Carriers; Flavonoids; Male; Micelles; Rats, Sprague-Dawley; Tissue Distribution; Vitamin E | 2019 |
Development and mechanistic study of a microemulsion containing vitamin E TPGS for the enhancement of oral absorption of celecoxib.
Topics: Administration, Oral; Animals; Celecoxib; Cell Death; Drug Liberation; Electric Conductivity; Electric Impedance; Emulsions; Humans; Intestinal Absorption; Intestinal Mucosa; Kinetics; Particle Size; Permeability; Rheology; Solubility; Static Electricity; Surface-Active Agents; Swine; Vitamin E | 2019 |
Solubilization of Carbamazepine in TPGS Micelles: Effect of Temperature and Electrolyte Addition.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Carriers; Electrolytes; Excipients; Hydrophobic and Hydrophilic Interactions; Micelles; Scattering, Small Angle; Solubility; Temperature; Vitamin E | 2019 |
TPGS-grafted and acid-responsive soy protein nanogels for efficient intracellular drug release, accumulation, penetration in 3D tumor spheroids of drug-resistant cancer cells.
Topics: A549 Cells; Adenosine Triphosphate; Apoptosis; Drug Liberation; Drug Resistance, Neoplasm; Endocytosis; Humans; Hydrodynamics; Inhibitory Concentration 50; Intracellular Space; Membrane Potential, Mitochondrial; Methacrylates; Nanogels; Particle Size; Polyethylene Glycols; Polyethyleneimine; Proton Magnetic Resonance Spectroscopy; Soybean Proteins; Spheroids, Cellular; Vitamin E | 2019 |
Anionic and Cationic Vitamin E-TPGS Mixed Polymeric Phospholipid Micellar Vehicles.
Topics: Antineoplastic Agents; Berberine; Cell Line, Tumor; Drug Delivery Systems; Humans; Hydrophobic and Hydrophilic Interactions; Male; Micelles; Nanoparticles; Nanostructures; Phospholipids; Prostatic Neoplasms; Solubility; Vitamin E | 2019 |
Enhanced oral delivery and anti-gastroesophageal reflux activity of curcumin by binary mixed micelles.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Caco-2 Cells; Curcumin; Drug Carriers; Drug Compounding; Drug Evaluation, Preclinical; Drug Liberation; Gastroesophageal Reflux; Humans; Intestinal Absorption; Intestinal Mucosa; Male; Mice; Micelles; Models, Animal; Permeability; Poloxamer; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Solubility; Stearic Acids; Vitamin E | 2019 |
Development of a nanoamorphous exosomal delivery system as an effective biological platform for improved encapsulation of hydrophobic drugs.
Topics: Antineoplastic Agents; Aspirin; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Drug Delivery Systems; Epoxy Compounds; Exosomes; Humans; Hydrophobic and Hydrophilic Interactions; Poloxamer; Vitamin E | 2019 |
Vitamin E D-alpha-tocopheryl polyethylene glycol 1000 succinate-conjugated liposomal docetaxel reverses multidrug resistance in breast cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Docetaxel; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Liposomes; MCF-7 Cells; Particle Size; Polyethylene Glycols; Succinates; Vitamin E | 2019 |
Dihydroartemisinin and doxorubicin co-loaded Soluplus
Topics: Antibiotics, Antineoplastic; Antimalarials; Artemisinins; Breast Neoplasms; Doxorubicin; Drug Carriers; Drug Combinations; Female; Humans; MCF-7 Cells; Micelles; Polyethylene Glycols; Polyvinyls; Vitamin E | 2019 |
Rapamycin loaded TPGS-Lecithins-Zein nanoparticles based on core-shell structure for oral drug administration.
Topics: Administration, Oral; Animals; Caco-2 Cells; Cell Survival; Coumarins; Drug Carriers; Drug Liberation; Humans; Intestinal Absorption; Lecithins; Male; Nanoparticles; Rats, Sprague-Dawley; Sirolimus; Thiazoles; Vitamin E; Zein | 2019 |
Therapeutic Effect of Sorafenib-Loaded TPGS-
Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Liver Neoplasms; Mice; Nanoparticles; Polyethylene Glycols; Sorafenib; Vitamin E | 2018 |
Differential Effects of TPM, A Phosphorylated Tocopherol Mixture, and Other Tocopherol Derivatives as Excipients for Enhancing the Solubilization of Co-Enzyme Q10 as a Lipophilic Drug During Digestion of Lipid- Based Formulations.
Topics: Digestion; Excipients; Fasting; Intestine, Small; Phosphorylation; Solubility; Triglycerides; Ubiquinone; Vitamin E | 2019 |
Docetaxel-loaded PAMAM-based poly (γ-benzyl-l-glutamate)-b-d-α-tocopheryl polyethylene glycol 1000 succinate nanoparticles in human breast cancer and human cervical cancer therapy.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Dendrimers; Docetaxel; Drug Carriers; Drug Liberation; Female; HeLa Cells; Humans; MCF-7 Cells; Mice, Inbred BALB C; Mice, Nude; Uterine Cervical Neoplasms; Vitamin E | 2019 |
Superiority of TPGS-loaded micelles in the brain delivery of vinpocetine via administration of thermosensitive intranasal gel.
Topics: Administration, Intranasal; Animals; Biological Availability; Brain; Cattle; Drug Carriers; Drug Delivery Systems; Gels; Lipids; Male; Micelles; Nanoparticles; Particle Size; Rats, Sprague-Dawley; Solubility; Temperature; Tissue Distribution; Vinca Alkaloids; Vitamin E | 2019 |
Induction of Mitochondrial Cell Death and Reversal of Anticancer Drug Resistance via Nanocarriers Composed of a Triphenylphosphonium Derivative of Tocopheryl Polyethylene Glycol Succinate.
Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Breast Neoplasms; Disease Models, Animal; Doxorubicin; Drug Carriers; Drug Delivery Systems; Drug Resistance, Neoplasm; Female; Humans; MCF-7 Cells; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mitochondria; Molecular Docking Simulation; Reactive Oxygen Species; Tissue Distribution; Vitamin E | 2019 |
Fabrication of capsaicin emulsions: improving the stability of the system and relieving the irritation to the gastrointestinal tract of rats.
Topics: Animals; Capsaicin; Emulsifying Agents; Emulsions; Gastrointestinal Tract; Male; Particle Size; Rats; Rats, Sprague-Dawley; Vitamin E | 2020 |
Topical anesthetic analgesic therapy using the combination of ropivacaine and dexmedetomidine: hyaluronic acid modified long-acting nanostructured lipid carriers containing a skin penetration enhancer.
Topics: Administration, Cutaneous; Analgesics; Anesthetics, Local; Animals; BALB 3T3 Cells; Dexmedetomidine; Drug Carriers; Drug Liberation; Hyaluronic Acid; Lipids; Mice; Nanoparticles; Nanostructures; Particle Size; Phosphatidylethanolamines; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Ropivacaine; Skin Absorption; Vitamin E | 2019 |
d-a-Tocopheryl Polyethylene Glycol 1000 Succinate and a small-molecule Survivin suppressant synergistically induce apoptosis in SKBR3 breast cancer cells.
Topics: Apoptosis; Breast Neoplasms; Drug Delivery Systems; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; MCF-7 Cells; Naphthoquinones; Survivin; Vitamin E | 2019 |
Pharmacokinetics and brain targeting of
Topics: Administration, Intravenous; Animals; Antioxidants; Area Under Curve; Biological Availability; Blood-Brain Barrier; Brain; Drug Carriers; Drug Delivery Systems; Male; Micelles; Particle Size; Poloxamer; Rats; Rats, Sprague-Dawley; Resveratrol; Tissue Distribution; Vitamin E | 2020 |
Injected laquinimod D-α-tocopheryl polyethylene glycol-1000 succinate polymeric micelles for the treatment of inflammatory bowel disease.
Topics: Animals; Colon; Dextran Sulfate; Drug Liberation; Inflammation; Inflammatory Bowel Diseases; Injections; Intestinal Mucosa; Mice, Inbred ICR; Micelles; Particle Size; Quinolones; Solubility; Spectroscopy, Fourier Transform Infrared; Static Electricity; Vitamin E | 2020 |
Genotoxicity and biocompatibility of superparamagnetic iron oxide nanoparticles: Influence of surface modification on biodistribution, retention, DNA damage and oxidative stress.
Topics: Animals; Biocompatible Materials; DNA Damage; Humans; Iron; Lymphocytes; Magnetite Nanoparticles; Male; Mice; Mutagenicity Tests; Mutagens; Oxidative Stress; Polylactic Acid-Polyglycolic Acid Copolymer; Quaternary Ammonium Compounds; Sperm Head; Surface Properties; Vitamin E | 2020 |
Development of conjugate-by-conjugate structured nanoparticles for oral delivery of docetaxel.
Topics: Administration, Oral; Antineoplastic Agents; Breast Neoplasms; Caco-2 Cells; Cell Line, Tumor; Chitosan; Docetaxel; Drug Carriers; Drug Delivery Systems; Female; Humans; Hydrogen-Ion Concentration; Hypromellose Derivatives; Intestinal Absorption; Nanoparticles; Particle Size; Vitamin E; X-Ray Diffraction | 2020 |
Specific Modification with TPGS and Drug Loading of Cyclodextrin Polyrotaxanes and the Enhanced Antitumor Activity Study in Vitro and in Vivo.
Topics: Animals; Anticarcinogenic Agents; Camptothecin; Cell Line, Tumor; Cellulose; Cyclodextrins; Drug Delivery Systems; Humans; Mice; Nanoparticles; Neoplasms; Rotaxanes; Vitamin E; Xenograft Model Antitumor Assays | 2019 |
Formulation, Characterization And Evaluation Of Curcumin- Loaded PLGA- TPGS Nanoparticles For Liver Cancer Treatment.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Curcumin; Dose-Response Relationship, Drug; Drug Compounding; Drug Screening Assays, Antitumor; Hep G2 Cells; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred Strains; Molecular Structure; Polylactic Acid-Polyglycolic Acid Copolymer; Structure-Activity Relationship; Vitamin E | 2019 |
In vitro and in vivo cardioprotective and metabolic efficacy of vitamin E TPGS/Apelin.
Topics: Animals; Apelin; Apoptosis; Cardiomegaly; Cardiotonic Agents; Cell Hypoxia; Cell Line; Diabetic Cardiomyopathies; Diet, High-Fat; Fibrosis; Isoproterenol; Mice, Inbred C57BL; Mitochondria; Myocytes, Cardiac; Oxidative Stress; Rats; Reactive Oxygen Species; Vascular Remodeling; Vitamin E | 2020 |
Development and Characterization of Nano-emulsions Based on Oil Extracted from Black Soldier Fly Larvae.
Topics: Animals; Diptera; Emulsions; Larva; Lecithins; Surface-Active Agents; Vitamin E | 2020 |
Vitamin E TPGS based transferosomes augmented TAT as a promising delivery system for improved transdermal delivery of raloxifene.
Topics: Administration, Cutaneous; Animals; Anticarcinogenic Agents; Breast Neoplasms; Drug Carriers; Female; Humans; MCF-7 Cells; Raloxifene Hydrochloride; Rats, Wistar; Selective Estrogen Receptor Modulators; Skin Absorption; tat Gene Products, Human Immunodeficiency Virus; Vitamin E | 2019 |
Doxorubicin Encapsulated in TPGS-Modified 2D-Nanodisks Overcomes Multidrug Resistance.
Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Doxorubicin; Drug Compounding; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Nanocapsules; Polyethylene Glycols; Vitamin E | 2020 |
Preparation, evaluation and metabolites study in rats of novel amentoflavone-loaded TPGS/soluplus mixed nanomicelles.
Topics: A549 Cells; Animals; Biflavonoids; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Stability; Humans; Male; Micelles; Nanoparticles; Particle Size; Polyethylene Glycols; Polyvinyls; Rats; Rats, Sprague-Dawley; Vitamin E | 2020 |
Co-encapsulation of docetaxel and thymoquinone in mPEG-DSPE-vitamin E TPGS-lipid nanocapsules for breast cancer therapy: Formulation optimization and implications on cellular and in vivo toxicity.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzoquinones; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Docetaxel; Drug Resistance, Neoplasm; Female; Humans; MCF-7 Cells; Mice; Mice, Inbred BALB C; Nanocapsules; Phosphatidylethanolamines; Polyethylene Glycols; Triple Negative Breast Neoplasms; Vitamin E | 2020 |
Study on the stabilization mechanisms of wet-milled cepharanthine nanosuspensions using systematical characterization.
Topics: Adsorption; Benzylisoquinolines; Carboxymethylcellulose Sodium; Drug Stability; Excipients; Nanoparticles; Nanotechnology; Polyethylene Glycols; Povidone; Suspensions; Vitamin E | 2020 |
Development of TPGS/F127/F68 mixed polymeric micelles: Enhanced oral bioavailability and hepatoprotection of syringic acid against carbon tetrachloride-induced hepatotoxicity.
Topics: Administration, Oral; Animals; Biological Availability; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Drug Carriers; Drug Delivery Systems; Gallic Acid; Humans; Liver; Male; Mice; Mice, Inbred ICR; Micelles; Nanoparticles; Oxidative Stress; Polyethylene Glycols; Polyethylenes; Polypropylenes; Propylene Glycols; Rats; Rats, Sprague-Dawley; Vitamin E | 2020 |
Structural characterization by scattering and spectroscopic methods and biological evaluation of polymeric micelles of poloxamines and TPGS as nanocarriers for miltefosine delivery.
Topics: Animals; Antiprotozoal Agents; Drug Carriers; Dynamic Light Scattering; Ethylenediamines; Leishmania major; Macrophages; Mice; Micelles; Molecular Structure; Nanoparticles; Phosphorylcholine; Spectrum Analysis; Vitamin E | 2020 |
Fabrication of nanopatterned PLGA films of curcumin and TPGS for skin cancer.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Curcumin; Drug Liberation; Humans; Mice; Nanoparticles; Particle Size; Polyethylene Glycols; Polylactic Acid-Polyglycolic Acid Copolymer; Skin Neoplasms; Vitamin E | 2020 |
Docetaxel-loaded D-α-tocopheryl polyethylene glycol-1000 succinate liposomes improve lung cancer chemotherapy and reverse multidrug resistance.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Docetaxel; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Liposomes; Lung Neoplasms; Mice; Mice, Nude; Polyethylene Glycols; Succinates; Vitamin E | 2021 |
Co-Delivery of Docetaxel and Salinomycin to Target Both Breast Cancer Cells and Stem Cells by PLGA/TPGS Nanoparticles.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Docetaxel; Drug Delivery Systems; Drug Liberation; Female; Humans; Liposomes; Male; MCF-7 Cells; Mice, Inbred BALB C; Nanoparticles; Neoplastic Stem Cells; Polylactic Acid-Polyglycolic Acid Copolymer; Pyrans; Rats, Sprague-Dawley; Tissue Distribution; Vitamin E; Xenograft Model Antitumor Assays | 2019 |
Efficacy of eye drops containing crosslinked hyaluronic acid and CoQ10 in restoring ocular health exposed to chlorinated water.
Topics: Administration, Ophthalmic; Adolescent; Adult; Chloramines; Conjunctival Diseases; Corneal Diseases; Cross-Linking Reagents; Disinfectants; Drug Combinations; Humans; Hyaluronic Acid; Hyperemia; Male; Ophthalmic Solutions; Osmolar Concentration; Prospective Studies; Quality of Life; Surveys and Questionnaires; Swimming Pools; Tears; Ubiquinone; Vitamin E; Vitamins; Water Pollutants, Chemical; Young Adult | 2020 |
Self-Assembly Nanoparticles for Overcoming Multidrug Resistance and Imaging-Guided Chemo-Photothermal Synergistic Cancer Therapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Doxorubicin; Drug Delivery Systems; Drug Liberation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Indocyanine Green; Nanoparticles; Phototherapy; Stomach Neoplasms; Theranostic Nanomedicine; Vitamin E | 2020 |
Tuning mPEG-PLA/vitamin E-TPGS-based mixed micelles for combined celecoxib/honokiol therapy for breast cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biphenyl Compounds; Breast Neoplasms; Celecoxib; Lignans; Mice; Mice, Inbred BALB C; Polyesters; Polyethylene Glycols; Vitamin E | 2020 |
Improving tumor hypoxia and radiotherapy resistance via in situ nitric oxide release strategy.
Topics: Animals; Apoptosis; Carcinoma, Lewis Lung; Cells, Cultured; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice, Inbred C57BL; Micelles; Neovascularization, Pathologic; Nitric Oxide; Nitric Oxide Donors; Radiation Tolerance; Radiation-Sensitizing Agents; Tumor Hypoxia; Vitamin E | 2020 |
Combination Therapy of Doxorubicin and Quercetin on Multidrug-Resistant Breast Cancer and Their Sequential Delivery by Reduction-Sensitive Hyaluronic Acid-Based Conjugate/d-α-Tocopheryl Poly(ethylene glycol) 1000 Succinate Mixed Micelles.
Topics: Animals; Antineoplastic Agents; Apoptosis; Biological Products; Breast; Breast Neoplasms; Cell Line, Tumor; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Hyaluronic Acid; Mice; Mice, Nude; Micelles; Polyethylene Glycols; Quercetin; Signal Transduction; Vitamin E | 2020 |
Preparation and characterization of antioxidant packaging by chitosan, D-α-tocopheryl polyethylene glycol 1000 succinate and baicalein.
Topics: Antioxidants; Chitosan; Flavanones; Food Packaging; Mechanical Phenomena; Solubility; Vitamin E; Water | 2020 |
Sorafenib-Loaded Nanoparticles Based on Biodegradable Dendritic Polymers for Enhanced Therapy of Hepatocellular Carcinoma.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Dendrimers; Drug Delivery Systems; Hep G2 Cells; Humans; Liver Neoplasms; Mice; Nanoparticles; Polymers; Sorafenib; Vitamin E; Xenograft Model Antitumor Assays | 2020 |
Synergistic effects of antitumor efficacy via mixed nano-size micelles of multifunctional Bletilla striata polysaccharide-based copolymer and D-α-tocopheryl polyethylene glycol succinate.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Doxorubicin; Drug Carriers; Drug Liberation; Female; Humans; Mice; Mice, Inbred BALB C; Micelles; Nanostructures; Orchidaceae; Polysaccharides; Tissue Distribution; Vitamin E | 2020 |
Development and evaluation of TPGS/PVA-based nanosuspension for enhancing dissolution and oral bioavailability of ticagrelor.
Topics: Administration, Oral; Animals; Biological Availability; Caco-2 Cells; Cell Survival; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Liberation; Humans; Male; Nanoparticles; Organ Culture Techniques; Polyvinyl Alcohol; Rats; Rats, Sprague-Dawley; Solubility; Ticagrelor; Vitamin E | 2020 |
Acid-breakable TPGS-functionalized and diallyl disulfide-crosslinked nanogels for enhanced inhibition of MCF-7/ADR solid tumours.
Topics: Allyl Compounds; Animals; Antineoplastic Agents; Disulfides; Doxorubicin; Drug Carriers; Drug Liberation; Humans; MCF-7 Cells; Mice; Mice, Nude; Nanogels; Neoplasms; Reactive Oxygen Species; Vitamin E | 2019 |
Mixed micelles of TPGS and Soluplus
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Female; Fenretinide; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Micelles; Paclitaxel; Polyethylene Glycols; Polyvinyls; Rats; Rats, Wistar; Tumor Burden; Vitamin E; Xenograft Model Antitumor Assays | 2020 |
Antitumor Effects of Docetaxel in Truncated Basic Fibroblast Growth Factor- Functionalized Liposomes Delivered by d-α-tocopheryl Polyethylene Glycol 2000 Succinate.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Docetaxel; Fibroblast Growth Factor 2; Liposomes; Mice; Mice, Inbred C57BL; Polyethylene Glycols; Succinates; Vitamin E | 2020 |
Characterization and Cytotoxicity of Polyprenol Lipid and Vitamin E-TPGS Hybrid Nanoparticles for Betulinic Acid and Low-Substituted Hydroxyl Fullerenol in MHCC97H and L02 Cells.
Topics: Antineoplastic Agents; Betulinic Acid; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Delivery Systems; Drug Liberation; Fullerenes; Humans; Lipids; Liver Neoplasms; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanoparticles; Pentacyclic Triterpenes; Polyprenols; Triterpenes; Vitamin E | 2020 |
Near IR responsive targeted integrated lipid polymer nanoconstruct for enhanced magnolol cytotoxicity in breast cancer.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Biphenyl Compounds; Breast Neoplasms; Cell Line, Tumor; Drug Carriers; Drug Compounding; Drug Liberation; Female; Gold; Humans; Lignans; Metal Nanoparticles; Microscopy, Confocal; Oxazines; Particle Size; Photothermal Therapy; Polylactic Acid-Polyglycolic Acid Copolymer; Proton Magnetic Resonance Spectroscopy; Spectroscopy, Fourier Transform Infrared; Surface Properties; Trastuzumab; Vitamin E | 2020 |
Galactosylated TPGS Micelles for Docetaxel Targeting to Hepatic Carcinoma: Development, Characterization, and Biodistribution Study.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Docetaxel; Drug Delivery Systems; Drug Development; Female; Galactose; Hep G2 Cells; Humans; Liver Neoplasms; Male; Random Allocation; Rats; Tissue Distribution; Vitamin E | 2020 |
Central composite design-based optimization of lopinavir vitamin E-TPGS micelle: In vitro characterization and in vivo pharmacokinetic study.
Topics: Drug Carriers; Lopinavir; Micelles; Particle Size; Polyethylene Glycols; Solubility; Vitamin E | 2020 |
Enhanced Oral Delivery of Curcumin via Vitamin E TPGS Modified Nanodiamonds: a Comparative Study on the Efficacy of Non-covalent and Covalent Conjugated Strategies.
Topics: Administration, Oral; Animals; Biological Availability; Caco-2 Cells; Curcumin; Drug Carriers; Humans; Male; Micelles; Nanodiamonds; Particle Size; Rats; Vitamin E | 2020 |
Hybrid micelles based on Pt (IV) polymeric prodrug and TPGS for the enhanced cytotoxicity in drug-resistant lung cancer cells.
Topics: Drug Resistance, Neoplasm; Humans; Lung Neoplasms; Micelles; Polymers; Prodrugs; Vitamin E | 2020 |
Rebaudioside A/TPGS mixed nanomicelles as promising nanocarriers for nimodipine ocular delivery.
Topics: Administration, Ophthalmic; Animals; Cornea; Diterpenes, Kaurane; Drug Carriers; Micelles; Nimodipine; Polyethylene Glycols; Rabbits; Vitamin E | 2021 |
Dual-responsive TPGS crosslinked nanocarriers to overcome multidrug resistance.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell-Penetrating Peptides; Doxorubicin; Drug Carriers; Drug Liberation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Fluorescence; Humans; MCF-7 Cells; Mice, Inbred BALB C; Micelles; Neoplasms; Polyethylene Glycols; Vitamin E | 2020 |
Morphology, gelation and cytotoxicity evaluation of D-α-Tocopheryl polyethylene glycol succinate (TPGS) - Tetronic mixed micelles.
Topics: alpha-Tocopherol; Micelles; Polyethylene Glycols; Vitamin E | 2021 |
Enhanced oral bioavailability of self-assembling curcumin-vitamin E prodrug-nanoparticles by co-nanoprecipitation with vitamin E TPGS.
Topics: Animals; Biological Availability; Curcumin; Drug Carriers; Nanoparticles; Polyethylene Glycols; Prodrugs; Rats; Rats, Sprague-Dawley; Vitamin E | 2020 |
Biomimetic microbioreactor-supramolecular nanovesicles improve enzyme therapy of hepatic cancer.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; Biomimetics; Enzyme Therapy; Humans; Hydrogen-Ion Concentration; Hydrolases; Liver Neoplasms; Vitamin E | 2021 |
Formulation and Evaluation of Supramolecular Food-Grade Piperine HP β CD and TPGS Complex: Dissolution, Physicochemical Characterization, Molecular Docking, In Vitro Antioxidant Activity, and Antimicrobial Assessment.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Alkaloids; Anti-Bacterial Agents; Antioxidants; Benzodioxoles; Drug Compounding; Hydrophobic and Hydrophilic Interactions; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Molecular Docking Simulation; Piperidines; Polyunsaturated Alkamides; Solubility; Spectroscopy, Fourier Transform Infrared; Vitamin E; X-Ray Diffraction | 2020 |
Paclitaxel-Loaded Colloidal Silica and TPGS-Based Solid Self-Emulsifying System Interferes Akt/mTOR Pathway in MDA-MB-231 and Demonstrates Anti-tumor Effect in Syngeneic Mammary Tumors.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biological Availability; Cell Line, Tumor; Colloids; Drug Delivery Systems; Emulsions; Humans; Mammary Neoplasms, Animal; Paclitaxel; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Research Design; Silicon Dioxide; TOR Serine-Threonine Kinases; Vitamin E | 2020 |
Topics: Administration, Oral; Animals; Blood Glucose; Deoxycholic Acid; Diabetes Mellitus, Experimental; Drug Carriers; Drug Delivery Systems; Drug Liberation; Hypoglycemic Agents; Insulin; Liposomes; Male; Nanoparticles; Particle Size; Phospholipids; Rats; Rats, Wistar; Vitamin E | 2021 |
Chemosensitizing micelles self-assembled from amphiphilic TPGS-indomethacin twin drug for significantly synergetic multidrug resistance reversal.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Apoptosis; Cell Proliferation; Drug Liberation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Humans; Indomethacin; MCF-7 Cells; Micelles; Mitochondria; Paclitaxel; Reactive Oxygen Species; Vitamin E | 2021 |
Enhanced cellular uptake and cytotoxicity of vorinostat through encapsulation in TPGS-modified liposomes.
Topics: Cell Line, Tumor; Liposomes; Particle Size; Polyethylene Glycols; Vitamin E; Vorinostat | 2021 |
Comparison of α-Tocopherol, α-Tocopherol Acetate, and α-Tocopheryl Polyethylene Glycol Succinate 1000 Absorption by Caco-2 TC7 Intestinal Cells.
Topics: alpha-Tocopherol; Biological Availability; Caco-2 Cells; Dietary Supplements; Humans; Intestinal Absorption; Intestinal Mucosa; Micelles; Vitamin E | 2020 |
Folic acid modified TPGS as a novel nano-micelle for delivery of nitidine chloride to improve apoptosis induction in Huh7 human hepatocellular carcinoma.
Topics: Antineoplastic Agents; Apoptosis; Benzophenanthridines; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Liberation; Folic Acid; Humans; Liver Neoplasms; Micelles; Nanoparticles; Vitamin E | 2021 |
Adequate formulation approach for oral chemotherapy: Etoposide solubility, permeability, and overall bioavailability from cosolvent- vs. vitamin E TPGS-based delivery systems.
Topics: Administration, Oral; Animals; Biological Availability; Etoposide; Permeability; Polyethylene Glycols; Rats; Solubility; Vitamin E | 2021 |
Bioadhesive polymer/lipid hybrid nanoparticles as oral delivery system of raloxifene with enhancive intestinal retention and bioavailability.
Topics: Acrylic Resins; Administration, Oral; Animals; Biological Availability; Caco-2 Cells; Diglycerides; Drug Carriers; Humans; Liposomes; Nanoparticles; Raloxifene Hydrochloride; Rats; Selective Estrogen Receptor Modulators; Vitamin E | 2021 |
Antipsychotic Potential and Safety Profile of TPGS-Based Mucoadhesive Aripiprazole Nanoemulsion: Development and Optimization for Nose-To-Brain Delivery.
Topics: Administration, Intranasal; Animals; Antipsychotic Agents; Aripiprazole; Brain; Drug Delivery Systems; Emulsions; Nanoparticles; Nasal Mucosa; Rats; Rats, Wistar; Sheep; Vitamin E | 2021 |
Box-Behnken Design Optimized TPGS Coated Bovine Serum Albumin Nanoparticles Loaded with Anastrozole.
Topics: Anastrozole; Drug Carriers; Nanoparticles; Particle Size; Polyethylene Glycols; Serum Albumin, Bovine; Vitamin E | 2021 |
Encapsulating Halofuginone Hydrobromide in TPGS Polymeric Micelles Enhances Efficacy Against Triple-Negative Breast Cancer Cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Compounding; Female; Humans; Membrane Potential, Mitochondrial; Mice, Inbred BALB C; Mice, Nude; Micelles; Paclitaxel; Piperidines; Polymers; Quinazolinones; Reactive Oxygen Species; Treatment Outcome; Triple Negative Breast Neoplasms; Vitamin E | 2021 |
Development and optimization of TPGS-based stealth liposome of doxorubicin using Box-Behnken design: characterization, hemocompatibility, and cytotoxicity evaluation in breast cancer cells.
Topics: alpha-Tocopherol; Breast Neoplasms; Cell Line, Tumor; Doxorubicin; Female; Humans; Liposomes; Polyethylene Glycols; Vitamin E | 2022 |
An Integrated Approach for High-Shear Wet Granulation (HSWG) Processing of TPGS-Based Formulations: Demonstration of Process Robustness through Experimental Design Conditions.
Topics: Drug Compounding; Excipients; Particle Size; Research Design; Tablets; Vitamin E | 2021 |
Preparation and In Vitro/Vivo Evaluation of Folate-conjugated Pluronic F87-PLGA/TPGS Mixed Nanoparticles for Targeted Drug Delivery.
Topics: Apoptosis; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Female; Folic Acid; Humans; Nanoparticles; Ovarian Neoplasms; Paclitaxel; Poloxamer; Polyethylene Glycols; Vitamin E | 2021 |
Development of Apremilast Solid Dispersion Using TPGS and PVPVA with Enhanced Solubility and Bioavailability.
Topics: Animals; Biological Availability; Calorimetry, Differential Scanning; Dosage Forms; Phosphodiesterase 4 Inhibitors; Povidone; Powder Diffraction; Rats; Solubility; Spectroscopy, Fourier Transform Infrared; Thalidomide; Vitamin E | 2021 |
Novel redox-sensitive thiolated TPGS based nanoparticles for EGFR targeted lung cancer therapy.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; ErbB Receptors; Lung Neoplasms; Mice; Nanoparticles; Oxidation-Reduction; Particle Size; Polyethylene Glycols; Rats; Vitamin E | 2021 |
Pterostilbene nanoparticles with small particle size show excellent anti-breast cancer activity
Topics: Animals; Antineoplastic Agents; Biological Availability; Breast Neoplasms; Drug Compounding; Female; HeLa Cells; Humans; Lecithins; MCF-7 Cells; Mice; Mice, Inbred BALB C; Nanoparticles; Paclitaxel; Particle Size; Solubility; Stilbenes; Treatment Outcome; Tumor Burden; Vitamin E; Xenograft Model Antitumor Assays | 2021 |
Docetaxel-loaded folate-modified TPGS-transfersomes for glioblastoma multiforme treatment.
Topics: Antineoplastic Agents; Cell Line, Tumor; Docetaxel; Drug Carriers; Folic Acid; Glioblastoma; Humans; Nanoparticles; Vitamin E | 2021 |
TPGS and chondroitin sulfate dual-modified lipid-albumin nanosystem for targeted delivery of chemotherapeutic agent against multidrug-resistant cancer.
Topics: Albumins; Animals; Breast Neoplasms; Cell Proliferation; Cell Survival; Chondroitin Sulfates; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Hyaluronan Receptors; Lipids; MCF-7 Cells; Mice; Nanoparticles; Paclitaxel; Vitamin E; Xenograft Model Antitumor Assays | 2021 |
TPGS assists the percutaneous administration of curcumin and glycyrrhetinic acid coloaded functionalized ethosomes for the synergistic treatment of psoriasis.
Topics: Administration, Cutaneous; Animals; Curcumin; Drug Carriers; Glycyrrhetinic Acid; Mice; Psoriasis; Vitamin E | 2021 |
Development of Gelucire
Topics: Biological Availability; Curcumin; Drug Carriers; Drug Liberation; Excipients; Micelles; Polyethylene Glycols; Polymethacrylic Acids; Solubility; Vitamin E; X-Ray Diffraction | 2021 |
A novel self-targeting theranostic nanoplatform for photoacoustic imaging-monitored and enhanced chemo-sonodynamic therapy.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Humans; Indocyanine Green; Mice; Molecular Structure; Nanoparticles; Neoplasms, Experimental; Optical Imaging; Particle Size; Photoacoustic Techniques; Prodrugs; Ultrasonic Therapy; Vitamin E | 2021 |
Exemestane encapsulated polymer-lipid hybrid nanoparticles for improved efficacy against breast cancer: optimization,
Topics: Androstadienes; Antineoplastic Agents; Biomimetic Materials; Cell Survival; Drug Carriers; Drug Compounding; Drug Liberation; Drug Stability; Factor Analysis, Statistical; Fluorescent Dyes; Gastric Juice; Humans; Kinetics; Liposomes; MCF-7 Cells; Nanoparticles; Phosphatidylcholines; Polyesters; Rhodamines; Vitamin E | 2021 |
The use of tocofersolan as a rescue agent in larval zebrafish exposed to benzo[a]pyrene in early development.
Topics: Animals; Benzo(a)pyrene; Female; Larva; Locomotion; Male; Oxidative Stress; Vitamin E; Water Pollutants, Chemical; Zebrafish | 2021 |
TPGS-Galactose-Modified Polydopamine Co-delivery Nanoparticles of Nitric Oxide Donor and Doxorubicin for Targeted Chemo-Photothermal Therapy against Drug-Resistant Hepatocellular Carcinoma.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Doxorubicin; Drug Carriers; Drug Liberation; Drug Resistance, Neoplasm; Drug Therapy; Galactose; Humans; Indoles; Infrared Rays; Liver Neoplasms; Male; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Nitric Oxide Donors; Nitroso Compounds; Photothermal Therapy; Polymers; Rats, Sprague-Dawley; Vitamin E; Xenograft Model Antitumor Assays | 2021 |
Amphiphilic tocopheryl polyethylene glycol succinate as gas chromatographic stationary phase for high-resolution separations of challenging isomers and analysis of lavender essential oil.
Topics: Gas Chromatography-Mass Spectrometry; Lavandula; Oils, Volatile; Plant Oils; Reproducibility of Results; Vitamin E | 2021 |
Brefeldin A delivery nanomicelles in hepatocellular carcinoma therapy: Characterization, cytotoxic evaluation in vitro, and antitumor efficiency in vivo.
Topics: Animals; Antineoplastic Agents; Apoptosis; Brefeldin A; Carcinoma, Hepatocellular; Cell Line; Cell Survival; Female; Humans; Liver Neoplasms; Mice, Inbred BALB C; Micelles; Nanostructures; Polyethylenes; Polypropylenes; Rats, Sprague-Dawley; Tissue Distribution; Vitamin E | 2021 |
Hybrid lipid core chitosan-TPGS shell nanocomposites as a promising integrated nanoplatform for enhanced oral delivery of sulpiride in depressive disorder therapy.
Topics: Administration, Oral; Caco-2 Cells; Chitosan; Depressive Disorder; Humans; Lipids; Nanocomposites; Sulpiride; Vitamin E | 2021 |
Evaluation of the Antitumor Effect and Immune Response of Micelles Modified with a Polysialic Acid-D-α-Tocopheryl Polyethylene Glycol 1000 Succinate Conjugate.
Topics: Antineoplastic Agents; Immunity; Micelles; Polyethylene Glycols; Sialic Acids; Succinates; Vitamin E | 2021 |
TPGS-Modified Long-Circulating Liposomes Loading Ziyuglycoside I for Enhanced Therapy of Myelosuppression.
Topics: alpha-Tocopherol; Animals; Drug Carriers; Liposomes; Mice; Particle Size; Polyethylene Glycols; Saponins; Vitamin E | 2021 |
N-trimethyl chitosan coated nano-complexes enhance the oral bioavailability and chemotherapeutic effects of gemcitabine.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Chitosan; Deoxycytidine; Drug Carriers; Drug Liberation; Gemcitabine; Male; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasms; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Sprague-Dawley; Vitamin E | 2021 |
Span 80/TPGS modified lipid-coated chitosan nanocomplexes of acyclovir as a topical delivery system for viral skin infections.
Topics: Acyclovir; Chitosan; Drug Carriers; Drug Delivery Systems; Hexoses; Lipids; Nanoparticles; Particle Size; Vitamin E | 2021 |
Surface-functionalized curcumin-loaded polymeric nanocapsules could block apomorphine-induced behavioral changes in rats.
Topics: Animals; Apomorphine; Behavior, Animal; Curcumin; Dopamine Agonists; Enzyme Inhibitors; Hexoses; Nanocapsules; Plants, Medicinal; Rats; Stereotyped Behavior; Treatment Outcome; Vitamin E | 2022 |
Application of TPGS as an efflux inhibitor and a plasticizer in baicalein solid dispersion.
Topics: Animals; Biological Availability; Caco-2 Cells; Drug Compounding; Flavanones; Humans; Mice; Plasticizers; Rats; Solubility; Vitamin E | 2022 |
Bioadhesive poly(methyl vinyl ether-co-maleic anhydride)-TPGS copolymer modified PLGA/lipid hybrid nanoparticles for improving intestinal absorption of cabazitaxel.
Topics: Intestinal Absorption; Lipids; Maleates; Nanoparticles; Polyethylenes; Taxoids; Vitamin E | 2022 |
Histopathological effects of topical coenzyme q 10 + Vit E TPGS in experimental ischemic optic neuropathy.
Topics: Animals; Disease Models, Animal; Male; Optic Neuropathy, Ischemic; Rats; Rats, Wistar; Ubiquinone; Vitamin E | 2022 |
Role of Surfactants on Release Performance of Amorphous Solid Dispersions of Ritonavir and Copovidone.
Topics: Drug Compounding; Drug Liberation; Hexoses; HIV Protease Inhibitors; Kinetics; Polysorbates; Pyrrolidines; Ritonavir; Solubility; Surface-Active Agents; Vinyl Compounds; Vitamin E | 2022 |
Bioavailability enhancement of vitamin E TPGS liposomes of nintedanib esylate: formulation optimization, cytotoxicity and pharmacokinetic studies.
Topics: Animals; Biological Availability; Carcinoma, Non-Small-Cell Lung; Drug Carriers; Indoles; Liposomes; Lung Neoplasms; Male; Particle Size; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Succinates; Vitamin E | 2022 |
Paclitaxel-Loaded TPGS
Topics: Biological Availability; Cell Line, Tumor; Cyclodextrins; Gelatin; HeLa Cells; Humans; Hyaluronic Acid; Nanoparticles; Paclitaxel; Vitamin E | 2022 |
"TPGS surface modified bilosomes as boosting cytotoxic oral delivery systems of curcumin against doxorubicin resistant MCF-7 breast cancer cells".
Topics: alpha-Tocopherol; Antineoplastic Agents; Breast Neoplasms; Caco-2 Cells; Curcumin; Doxorubicin; Female; Humans; MCF-7 Cells; Particle Size; Polyethylene Glycols; Vitamin E | 2022 |
Sorafenib-Loaded PLGA-TPGS Nanosystems Enhance Hepatocellular Carcinoma Therapy Through Reversing P-Glycoprotein-Mediated Multidrug Resistance.
Topics: alpha-Tocopherol; Animals; ATP Binding Cassette Transporter, Subfamily B; Carcinoma, Hepatocellular; Drug Resistance, Multiple; Glycolates; Humans; Lactic Acid; Liver Neoplasms; Mice; Mice, Nude; Polyesters; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Sorafenib; Vitamin E | 2022 |
Combinational treatment of TPEN and TPGS induces apoptosis in acute lymphoblastic and chronic myeloid leukemia cells in vitro and ex vivo.
Topics: Apoptosis; Child; Ethylenediamines; Humans; Jurkat Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Signal Transduction; Vitamin E | 2022 |
Orally Administered Halofuginone-Loaded TPGS Polymeric Micelles Against Triple-Negative Breast Cancer: Enhanced Absorption and Efficacy with Reduced Toxicity and Metastasis.
Topics: Animals; Caco-2 Cells; Cell Line, Tumor; Humans; Mice; Mice, Nude; Micelles; Piperidines; Polymers; Quinazolinones; Triple Negative Breast Neoplasms; Vitamin E | 2022 |
TPGS-based and S-thanatin functionalized nanorods for overcoming drug resistance in Klebsiella pneumonia.
Topics: Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Drug Resistance; Drug Resistance, Bacterial; Klebsiella Infections; Klebsiella pneumoniae; Mice; Microbial Sensitivity Tests; Nanotubes; Pneumonia; Polyethylene Glycols; Succinates; Tigecycline; Vitamin E | 2022 |
Lipid- and TPGS-Based Core-Shell-Type Nanocapsules Endowed with High Paclitaxel Loading and Enhanced Anticancer Potential.
Topics: alpha-Tocopherol; Cell Line, Tumor; Humans; Lipids; Nanocapsules; Paclitaxel; Polyethylene Glycols; Vitamin E | 2022 |
TPGS loaded triphenyltin (IV) micelles induced apoptosis by upregulating p53 in breast cancer cells and inhibit tumor progression in T-cell lymphoma bearing mice.
Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Line, Tumor; Female; Ligands; Lymphoma, T-Cell; Mice; Micelles; Organotin Compounds; Proto-Oncogene Proteins c-bcl-2; Tumor Suppressor Protein p53; Vitamin E | 2022 |
Enhanced Influenza Immunity by Nasal Mucosal Administration of the TPGS-Modified Liposomal Vaccine.
Topics: Adjuvants, Immunologic; Administration, Intranasal; alpha-Tocopherol; Animals; Antibodies, Viral; Humans; Immunoglobulin A; Immunoglobulins; Influenza Vaccines; Influenza, Human; Interferon-gamma; Lipids; Liposomes; Mice; Mice, Inbred BALB C; Phosphorylcholine; Polyethylene Glycols; Vitamin E | 2022 |
Small Angle X-Ray Scattering Data Analysis and Theoretical Modelling for the Size and Shape Characterization of Drug Delivery Systems Based on Vitamin E TPGS Micelles.
Topics: Data Analysis; Drug Delivery Systems; Micelles; Models, Theoretical; Polyethylene Glycols; Scattering, Small Angle; Vitamin E; X-Ray Diffraction; X-Rays | 2023 |
A novel micellar carrier to reverse multidrug resistance of tumours: TPGS derivatives with end-grafted cholesterol.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cholesterol; Docetaxel; Drug Resistance, Multiple; Female; Humans; Mice; Mice, Nude; Micelles; Ovarian Neoplasms; Polyethylene Glycols; Vitamin E | 2023 |
Enhanced apoptosis and mitochondrial cell death by paclitaxel-loaded TPP-TPGS
Topics: Animals; Apoptosis; Cell Line, Tumor; Mice; Paclitaxel; Polyethylene Glycols; Tissue Distribution; Vitamin E | 2023 |
Comparison of topographic outcomes between HPMC based and vitamin E TPGS based riboflavin solutions after corneal cross-linking.
Topics: Collagen; Corneal Cross-Linking; Corneal Topography; Cross-Linking Reagents; Humans; Hypromellose Derivatives; Keratoconus; Photochemotherapy; Photosensitizing Agents; Retrospective Studies; Riboflavin; Ultraviolet Rays; Vitamin E | 2023 |
Size-optimized simvastatin-loaded TPGS modified lipid nanocapsules for targeting epithelial-to-mesenchymal transition in hepatocellular carcinoma: Role of PTEN/AKT signaling.
Topics: alpha-Tocopherol; Carcinoma, Hepatocellular; Cell Line, Tumor; Humans; Lipids; Liver Neoplasms; Nanocapsules; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Simvastatin; Tissue Distribution | 2023 |
[Preparation of an ophthalmic formulation of TPGS-modified insulin-loaded liposomes and its
Topics: Animals; Cornea; Endothelial Cells; Fluorescein; Humans; Insulin; Lipopolysaccharides; Liposomes; Rabbits; Vitamin E | 2023 |
Fabrication of D-α-tocopheryl polyethylene glycol 1000 succinates and human serum albumin conjugated chitosan nanoparticles of bosutinib for colon targeting application; in vitro-in vivo investigation.
Topics: Animals; Chitosan; Colorectal Neoplasms; Drug Carriers; Humans; Male; Nanoparticles; Particle Size; Polyethylene Glycols; Rats; Succinates; Vitamin E | 2023 |