Page last updated: 2024-08-23

tobramycin and metronidazole

tobramycin has been researched along with metronidazole in 44 studies

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-199019 (43.18)18.7374
1990's11 (25.00)18.2507
2000's7 (15.91)29.6817
2010's5 (11.36)24.3611
2020's2 (4.55)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Brunner, LS; Haas, W; Lee, JC; Morris, TW; Pillar, CM; Zurenko, GE1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Kohl, S; Pickering, LK1
McAllister, TA1
Koch, JM; Reuber, H1
Heikkinen, E; Seppänen, J; Uhari, M1
Goodwin, SD; Heyd, A; Nix, DE; Wilton, JH1
Gattereau, D; Knoefel, F; Morisset, ME; Morisset, R; Rousseau, S1
Dahl, V; Johnstad, B1
Christou, NV; De Santis, M; Poenaru, D1
Haas, CE; Nix, DE; Schentag, JJ1
Davey, MR; van Iddekinge, B1
Stassen, LP; van der Werken, C; van Vroonhoven, TJ1
Dehne, M; el Abed, K; Hofmann, W; Kroh, U; Lennartz, H1
Bell, GA; Forget, JP; Forward, AD; Murphy, J; Smith, JA1
Bourke, JB; Foster, GE; Graham, TR; Hardcastle, JD; Reynolds, JR1
Lenderink, AW; Oostvogel, HJ; van der Werken, C; van Vroonhoven, TJ1
Pastorek, JG; Phelan, M; Ragan, FA1
Bell, RG; Lipford, LC; Massanari, MJ; Riley, CM1
Becker, P; Cassel, R; Hinder, RA; Kleinman, M; Koornhof, HJ; Myburgh, JA; Naude, G; Perrott, CA; Taubin, A1
Béland, L; Biron, S; Bourque, RA; Brochu, G; Marceau, P; Piché, P; Potvin, M1
Bell, GA; Forward, AD; Murphy, JM; Skidmore, AG; Smith, JA; Sutherland, E1
Aeberhard, P; Hassler, H; Kläy, K1
Bell, GA; Fothergill, J; Murphy, J; Smith, JA1
Bell, GA; Murphy, J; Smith, JA1
Clarke, AM; Forward, AD; Skidmore, AG; Smith, JA; Sutherland, E1
Addison, WA; Ayers, OM; Gall, SA; Hill, GB; Hughes, CE; Kohan, AP1
Bell, GA; Forward, AD; Murphy, JM; Skidmore, AG; Smith, JA1
Cooper, DA; Lowenthal, RM1
Hatzis, A; Kontogiannis, P; Mantzaris, GJ; Triadaphyllou, G1
Endo, M; Okabe, S; Yabata, E1
Aschoff, R; Baldauf, A; Leike, S; Meurer, M; Wirth, MP1
Aguilar, MM; Alcaide, MJ; Arroyo, A; Bellón, M; Calpena, R; Candela, F; Moya, P; Pérez-Vázquez, MT; Rodríguez-Prieto, MA1
Dilley, M; Geng, B1
Boettcher, M; Dennebaum, M; Elrod, J; Koenigs, I; Mohr, C; Reinshagen, K; Vincent, D; Yarmal, F1

Reviews

3 review(s) available for tobramycin and metronidazole

ArticleYear
Recent advances in antimicrobial therapy.
    Southern medical journal, 1977, Volume: 70, Issue:10

    Topics: Amikacin; Amoxicillin; Anti-Bacterial Agents; Cephalosporins; Clindamycin; Humans; Metronidazole; Sisomicin; Spectinomycin; Sulfamethoxazole; Ticarcillin; Tobramycin; Trimethoprim

1977
Recent advances in antibiotics.
    Scottish medical journal, 1976, Volume: 21, Issue:4

    Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Antitubercular Agents; Bacteria; Bacterial Infections; Cephalosporins; Cephamycins; Flucytosine; Gentamicins; Metronidazole; Penicillins; Plasmids; Sisomicin; Tobramycin

1976
Immediate and Delayed Hypersensitivity Reactions to Antibiotics: Aminoglycosides, Clindamycin, Linezolid, and Metronidazole.
    Clinical reviews in allergy & immunology, 2022, Volume: 62, Issue:3

    Topics: Aminoglycosides; Anaphylaxis; Angioedema; Anti-Bacterial Agents; Clindamycin; Dermatitis, Allergic Contact; Drug Eruptions; Drug Hypersensitivity; Eosinophilia; Humans; Hypersensitivity, Delayed; Immunoglobulin E; Linezolid; Metronidazole; Tobramycin

2022

Trials

14 trial(s) available for tobramycin and metronidazole

ArticleYear
Imipenem-cilastatin vs. tobramycin and metronidazole for appendicitis-related infections.
    The Pediatric infectious disease journal, 1992, Volume: 11, Issue:6

    Topics: Adolescent; Anti-Bacterial Agents; Appendicitis; Bacterial Infections; Child; Child, Preschool; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Therapy, Combination; Female; Humans; Imipenem; Infant; Male; Metronidazole; Tobramycin

1992
Imipenem versus tobramycin--antianaerobe antibiotic therapy in intra-abdominal infections.
    Canadian journal of surgery. Journal canadien de chirurgie, 1990, Volume: 33, Issue:5

    Topics: Abdomen; Adult; Aged; Bacteria, Anaerobic; Bacterial Infections; Clindamycin; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Imipenem; Male; Metronidazole; Middle Aged; Prospective Studies; Random Allocation; Tobramycin

1990
Piperacillin in colorectal surgery.
    The Journal of hospital infection, 1985, Volume: 6, Issue:4

    Topics: Abscess; Colonic Diseases; Humans; Metronidazole; Piperacillin; Random Allocation; Rectal Diseases; Surgical Wound Infection; Tobramycin

1985
Single-dose v. short-term antibiotic therapy for prevention of wound infection in general surgery. A prospective, randomized double-blind trial.
    Acta chirurgica Scandinavica, 1987, Volume: 153, Issue:10

    Topics: Adult; Aged; Anti-Bacterial Agents; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Metronidazole; Middle Aged; Penicillins; Prospective Studies; Random Allocation; Surgical Wound Infection; Tobramycin

1987
Prophylactic antimicrobials in elective colorectal and biliary surgery.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1985, Sep-14, Volume: 68, Issue:6

    Topics: Aged; Biliary Tract Surgical Procedures; Cefoxitin; Colon; Female; Humans; Male; Metronidazole; Middle Aged; Penicillins; Premedication; Random Allocation; Rectum; Surgical Wound Infection; Tobramycin

1985
Short-term antibiotherapy for peritonitis: prospective, randomized trial comparing cefotaxime-metronidazole and clindamycin-tobramycin.
    The Journal of antimicrobial chemotherapy, 1984, Volume: 14 Suppl B

    Topics: Cefotaxime; Clindamycin; Clinical Trials as Topic; Diverticulitis; Drug Combinations; Humans; Metronidazole; Peritonitis; Prospective Studies; Random Allocation; Tobramycin

1984
Metronidazole in the treatment of intra-abdominal sepsis.
    Surgery, 1983, Volume: 93, Issue:1 Pt 2

    Topics: Abdomen; Abscess; Adult; Aged; Appendicitis; Bacterial Infections; Clindamycin; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Metronidazole; Middle Aged; Peritonitis; Prospective Studies; Random Allocation; Tobramycin

1983
[Perioperative antibiotic prophylaxis in colon surgery. Metronidazole and tobramycin versus metronidazole alone. A prospective randomized study].
    Schweizerische medizinische Wochenschrift, 1983, Mar-19, Volume: 113, Issue:11

    Topics: Aged; Anti-Bacterial Agents; Clinical Trials as Topic; Colon; Drug Therapy, Combination; Female; Humans; Male; Metronidazole; Middle Aged; Premedication; Prospective Studies; Random Allocation; Tobramycin

1983
Intravenous prophylactic antimicrobial drugs in elective colorectal operations.
    Surgery, gynecology & obstetrics, 1983, Volume: 156, Issue:3

    Topics: Anti-Bacterial Agents; Double-Blind Method; Drug Therapy, Combination; Erythromycin; Female; Humans; Infusions, Parenteral; Intestine, Large; Male; Metronidazole; Postoperative Complications; Random Allocation; Tobramycin

1983
Prophylactic antibiotics in elective colon surgery.
    Surgery, 1983, Volume: 93, Issue:1 Pt 2

    Topics: Adult; Colon; Double-Blind Method; Drug Therapy, Combination; Erythromycin; Humans; Infusions, Parenteral; Metronidazole; Premedication; Prospective Studies; Random Allocation; Rectum; Surgical Wound Infection; Tobramycin

1983
Prospective, randomized, double-blind comparison of metronidazole and tobramycin with clindamycin and tobramycin in the treatment of intra-abdominal sepsis.
    Annals of surgery, 1980, Volume: 192, Issue:2

    Topics: Abdomen; Adult; Anti-Bacterial Agents; Bacterial Infections; Blood Urea Nitrogen; Clindamycin; Clinical Trials as Topic; Creatinine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Metronidazole; Middle Aged; Prospective Studies; Tobramycin

1980
Intravenous metronidazole or clindamycin with tobramycin for therapy of pelvic infections.
    Obstetrics and gynecology, 1981, Volume: 57, Issue:1

    Topics: Anti-Bacterial Agents; Bacterial Infections; Clindamycin; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Genital Diseases, Female; Humans; Metronidazole; Random Allocation; Suction; Tobramycin

1981
Intravenous tobramycin and metronidazole as an adjunct to corticosteroids in acute, severe ulcerative colitis.
    The American journal of gastroenterology, 1994, Volume: 89, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Chemotherapy, Adjuvant; Colitis, Ulcerative; Drug Therapy, Combination; Female; Humans; Hydrocortisone; Injections, Intravenous; Male; Metronidazole; Middle Aged; Prospective Studies; Tobramycin

1994
A prospective, randomized clinical trial of preoperative bowel preparation for elective colorectal surgery--comparison among oral, systemic, and intraoperative luminal antibacterial preparations.
    Journal of medical and dental sciences, 1997, Volume: 44, Issue:4

    Topics: Administration, Oral; Administration, Topical; Adult; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefmetazole; Colectomy; Colorectal Neoplasms; Female; Humans; Infusions, Intravenous; Intraoperative Care; Male; Metronidazole; Middle Aged; Preoperative Care; Prospective Studies; Surgical Wound Infection; Tobramycin

1997

Other Studies

27 other study(ies) available for tobramycin and metronidazole

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Besifloxacin, a novel fluoroquinolone, has broad-spectrum in vitro activity against aerobic and anaerobic bacteria.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:8

    Topics: Anti-Bacterial Agents; Azepines; Bacteria, Anaerobic; Drug Resistance, Bacterial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Septicaemia.
    Scottish medical journal, 1975, Volume: 20, Issue:2

    Topics: Cefazolin; Cephaloridine; Cephalothin; Cephradine; Clindamycin; Drug Resistance, Microbial; Flucytosine; Gentamicins; Humans; Lincomycin; Metronidazole; Sepsis; Shock, Septic; Tobramycin

1975
[Acanthamoeba keratitis caused by extended wear contact lenses].
    Klinische Monatsblatter fur Augenheilkunde, 1992, Volume: 200, Issue:1

    Topics: Acanthamoeba Keratitis; Administration, Oral; Aged; Cataract Extraction; Contact Lenses, Extended-Wear; Drug Therapy, Combination; Female; Humans; Metronidazole; Ophthalmic Solutions; Postoperative Complications; Tobramycin

1992
Compatibility of ciprofloxacin injection with selected drugs and solutions.
    American journal of hospital pharmacy, 1991, Volume: 48, Issue:10

    Topics: Amikacin; Anti-Bacterial Agents; Ciprofloxacin; Clindamycin; Drug Compounding; Drug Incompatibility; Drug Stability; Drug Storage; Drug Therapy, Combination; Gentamicins; Metronidazole; Solutions; Theophylline; Tobramycin

1991
The role of laparoscopy in acute pelvic infections.
    European journal of obstetrics, gynecology, and reproductive biology, 1991, Jun-05, Volume: 40, Issue:1

    Topics: Acute Disease; Adult; Ampicillin; Chlamydia Infections; Drug Therapy, Combination; Female; Gonorrhea; Humans; Laparoscopy; Metronidazole; Mycoplasma Infections; Netilmicin; Pelvic Inflammatory Disease; Penicillin G Procaine; Tetracycline; Tobramycin

1991
[Gram positive septicemia].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1990, Jun-10, Volume: 110, Issue:15

    Topics: Adolescent; Adult; Female; Humans; Metronidazole; Norway; Penicillins; Sepsis; Shock, Septic; Streptococcal Infections; Streptococcus pyogenes; Tobramycin

1990
In vitro selection of resistant Helicobacter pylori.
    Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:9

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; Erythromycin; Helicobacter pylori; Metronidazole; Microbial Sensitivity Tests; Serial Passage; Tobramycin

1990
Conservative approach to the management of pelvic inflammatory disease.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1990, Mar-03, Volume: 77, Issue:5

    Topics: Amoxicillin; Anti-Bacterial Agents; Drug Therapy, Combination; Female; Humans; Metronidazole; Oxytetracycline; Pelvic Inflammatory Disease; Penicillin G; Prospective Studies; Tetracycline; Tobramycin

1990
[Prevention of wound infection following abdominal surgery].
    Nederlands tijdschrift voor geneeskunde, 1990, Apr-07, Volume: 134, Issue:14

    Topics: Abdomen; Amoxicillin; Drug Therapy, Combination; Humans; Metronidazole; Postoperative Care; Surgical Wound Infection; Tobramycin; Wound Healing

1990
[Dosage adjustment of drugs during continuous hemofiltration. Results and practical consequences of a prospective clinical study].
    Der Anaesthesist, 1989, Volume: 38, Issue:5

    Topics: Adult; Aged; Cefotaxime; Ceftazidime; Digitoxin; Digoxin; Hemofiltration; Humans; Imipenem; Kidney Failure, Chronic; Metronidazole; Middle Aged; Netilmicin; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Theophylline; Tobramycin; Vancomycin

1989
Evaluation of the use of a protocol in the antimicrobial treatment of intra-abdominal sepsis.
    The Journal of hospital infection, 1985, Volume: 6, Issue:1

    Topics: Adult; Anti-Bacterial Agents; Appendicitis; Bacteria; Drug Administration Schedule; Humans; Metronidazole; Peritonitis; Prospective Studies; Retrospective Studies; Tobramycin

1985
Tobramycin dosing in the puerperal patient.
    The Journal of reproductive medicine, 1987, Volume: 32, Issue:5

    Topics: Cesarean Section; Drug Therapy, Combination; Endometritis; Female; Humans; Kinetics; Metronidazole; Postoperative Complications; Pregnancy; Puerperal Disorders; Tobramycin

1987
Stability of intravenous admixtures of aztreonam and cefoxitin, gentamicin, metronidazole, or tobramycin.
    American journal of hospital pharmacy, 1986, Volume: 43, Issue:6

    Topics: Aztreonam; Cefoxitin; Drug Combinations; Drug Stability; Drug Storage; Gentamicins; Glucose; Metronidazole; Sodium Chloride; Tobramycin

1986
Metronidazole and tobramycin in intra-abdominal sepsis.
    Surgery, gynecology & obstetrics, 1982, Volume: 155, Issue:2

    Topics: Abdomen; Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Drug Therapy, Combination; Female; Humans; Infusions, Parenteral; Male; Metronidazole; Middle Aged; Tobramycin

1982
Complete regression of locally-advanced breast cancer with chemotherapy.
    The Medical journal of Australia, 1981, Apr-18, Volume: 1, Issue:8

    Topics: Aged; Breast Neoplasms; Carcinoma; Drug Therapy, Combination; Female; Humans; Metronidazole; Tobramycin

1981
[Extensive Fournier gangrene. A dermatologic emergency].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2006, Volume: 57, Issue:3

    Topics: Adult; Cefotaxime; Combined Modality Therapy; Drug Therapy, Combination; Emergencies; Follow-Up Studies; Fournier Gangrene; Genital Diseases, Male; Humans; Male; Metronidazole; Necrosis; Penile Diseases; Scrotum; Skin; Streptococcal Infections; Streptococcus pyogenes; Tobramycin

2006
Photodynamic therapy for the treatment of complex anal fistula.
    Techniques in coloproctology, 2017, Volume: 21, Issue:2

    Topics: Adolescent; Adult; Aged; Aminolevulinic Acid; Anti-Infective Agents; Antibiotic Prophylaxis; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Injections; Laser Therapy; Male; Metronidazole; Middle Aged; Photochemotherapy; Photosensitizing Agents; Rectal Fistula; Tobramycin; Treatment Outcome; Young Adult

2017
Are We Hitting the Target?: The Effectiveness of Distinct Antibiotic Regimens in Pediatric Appendectomies.
    The Pediatric infectious disease journal, 2022, 06-01, Volume: 41, Issue:6

    Topics: Anti-Bacterial Agents; Appendectomy; Appendicitis; Child; Humans; Metronidazole; Retrospective Studies; Tobramycin

2022