Page last updated: 2024-08-23

tobramycin and meropenem

tobramycin has been researched along with meropenem in 121 studies

Research

Studies (121)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	11 (9.09)	18.2507
2000's	53 (43.80)	29.6817
2010's	42 (34.71)	24.3611
2020's	15 (12.40)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Furuno, JP; Graffunder, E; Graves, J; Lodise, TP; Lomaestro, B; McGregor, JC; McNutt, LA; Miller, CD	1
Adams, J; de Oliveira Garcia, D; Doi, Y; Paterson, DL	1
Dumas, JL; Köhler, T; Reinhardt, A; Ricou, B; Rohner, P; van Delden, C; Wood, P	1
Correa, A; Kattan, JN; Lolans, K; Lopez, JA; Quinn, JP; Villegas, MV	1
Caniça, M; Ferreira, E; Leitão, J; Manageiro, V; Mendonça, N	1
Bonomo, RA; Endimiani, A; Hujer, AM; Hujer, KM; Luzzaro, F; Mantengoli, E; Migliavacca, R; Pagani, L; Rossolini, GM; Toniolo, A	1
Ariza, J; Dominguez, MA; Gudiol, F; Guzmán, A; Peña, C; Pujol, M; Suarez, C; Tubau, F	1
Adams, J; Paterson, DL; Peleg, AY	1
Avlami, A; Daikos, GL; Katsilambros, N; Kosmidis, C; Petrikkos, G; Psychogiou, M; Stefanou, I; Tassios, PT; Vasilakopoulou, A	1
Borrell, N; Maciá, MD; Moya, B; Oliver, A; Pérez, JL; Plasencia, V	1
Castanheira, M; Jones, RN; Mendes, RE; Sader, HS; Toleman, MA; Walsh, TR	1
Beceiro, A; Bou, G; Canle, D; Fernández, A; Lasa, I; Latasa, C; Mallo, S; Molina, F; Pérez, A; Pérez, S; Poza, M; Tomás, Mdel M; Villanueva, R	1
Bouza, E; Cercenado, E; Coll, P; Gutiérrez, O; Juan, C; Navarro, F; Oliver, A; Pérez, JL	1
Castanheira, M; Deshpande, LM; Martin, CA; Morita, K; Ribes, JA; Sader, HS	1
Bethel, CR; Bonomo, RA; Carias, LL; Endimiani, A; Fox, WR; Hall, GS; Hujer, AM; Hujer, KM; Hutton, RA; Jacobs, MR; Jenkins, SG; Paterson, DL; Perez, F; Rice, LB; Tenover, FC	1
Lombardo, F; Obach, RS; Waters, NJ	1
Alba, V; Blasco, MD; Espinal, P; Fernández-Cuenca, F; Marti, S; Pascual, A; Ruiz, M; Sánchez-Céspedes, J; Vila, J	1
Badur, S; Cagatay, AA; Carrër, A; Eraksoy, H; Nordmann, P; Poirel, L	1
Bauernfeind, A; Keuleyan, E; Markovska, R; Queenan, AM; Rasshofer, R; Schneider, I	1
Bratu, S; Georgescu, C; Landman, D; Martin, DA; Quale, J	1
Albertí, S; Beceiro, A; Bou, G; Garau, M; Gutiérrez, O; Juan, C; Oliver, A; Pérez, JL	1
Wang, H; Wu, X; Zhao, X	1
Adams-Haduch, JM; Doi, Y; Harrison, LH; Muto, CA; Pasculle, AW; Paterson, DL; Potoski, BA; Sidjabat, HE	1
Bennett, JW; Herrera, ML; Jorgensen, JH; Lewis, JS; Wickes, BW	1
Baptista, BC; Correia, JD; da Fonseca, JD; Martínez-Martínez, L; Pomba, C	1
Bell, JM; Castanheira, M; Deshpande, LM; Jones, RN; Mendes, RE; Turnidge, JD	1
Bell, JM; Castanheira, M; Jones, RN; Mathai, D; Turnidge, JD	1
Duljasz, W; Gniadkowski, M; Jebelean, C; Sitter, S; Wojna, A	1
Kirikae, T; Kitao, T; Miyoshi-Akiyama, T	1
Hall, RM; Post, V	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Carattoli, A; Ellington, MJ; Karisik, E; Livermore, DM; Underwood, A; Woodford, N	1
Acosta, J; Chaves, F; Juan, C; Oliver, A; Otero, JR; Sanz, F; Viedma, E; Zamorano, L	1
Albertí, S; Juan, C; Mulet, X; Oliver, A; Pérez, JL; Zamorano, L	1
Bulik, CC; Crandon, JL; Nicolau, DP	1
Albertí, S; Bengoechea, JA; Doménech-Sánchez, A; Llobet, E; Martínez-Martínez, L; Padilla, E	1
Bulik, CC; Christensen, H; Nicolau, DP	1
Ge, Y; Juan, C; Oliver, A; Pérez, JL; Zamorano, L	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Dunman, PM; Hood, MI; Jacobs, AC; Sayood, K; Skaar, EP	1
Beceiro, A; Bou, G; Doumith, M; Livermore, DM; Tomás, M; Turton, JF; Warner, M; Woodford, N	1
Chang, SC; Chen, YC; Hsia, KC; Li, SY; Liao, MH; Lin, YC; Sheng, WH	1
Chang, FY; Chen, TL; Fung, CP; Huang, LY; Lu, PL; Siu, LK	1
Barber, M; Eberly, LE; Feeney, LA; Miller, GH; Summers, A; Wortmann, G; Zapor, MJ	1
Abele-Horn, M; Claus, H; Elias, J; Engelhardt, K; Frosch, M; Joseph, B; Oesterlein, A; Schoen, C; Turnwald, D; Valenza, G	1
Cars, O; Löwdin, E; Melhus, A; Tängdén, T	1
Blázquez, J; Couce, A; Rodríguez-Rojas, A	1
Hamprecht, A; Higgins, PG; Schneiders, T; Seifert, H	1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Maravić, A; Odžak, R; Skočibušić, M	1
Banerjee, A; Chakrapani, H; Lahiri, S; Malwal, SR; Pardeshi, KA; Rangarajan, R	1
Fernando, DM; Gorityala, BK; Goswami, S; Guchhait, G; Kumar, A; Schweizer, F; Zhanel, GG	1
Chen, CL; Deng, Y; Fyfe, C; Grossman, TH; Hunt, DK; Sun, C; Sutcliffe, JA; Xiao, XY	1
Domalaon, R; Gorityala, BK; Goswami, S; Idowu, T; Lyu, Y; Schweizer, F; Shan, A; Yang, X; Zhanel, GG	1
Bojkovic, J; Dean, CR; Dobler, M; Dzink-Fox, J; Glick, M; Hamann, LG; Kerrigan, J; Lanieri, L; Lenoir, F; Lilly, MD; Liu, E; Lu, Y; McKenney, D; Nunez, J; Osborne, C; Parker, DT; Patnaik, A; Peng, Y; Piizzi, G; Ranjitkar, S; Sprague, ER; Tommasi, R; Wang, B; Wang, H; Wattanasin, S; Xie, L; Yang, X; Yu, D	1
Arthur, G; Idowu, T; Schweizer, F; Zhanel, GG	1
Jiang, K; Lin, F; Wu, H; Xiao, J; Xiao, Z; Yan, X; Yu, J; Yue, Y; Zhao, M; Zhou, X	1
Lohan, S; Mohammed, EHM; Parang, K; Tiwari, RK	1
Arhema Frejat, FO; Cao, Y; Kong, X; Liu, H; Luo, C; Ren, C; Shi, X; Wang, H; Wu, C; Yang, P; Yang, Y; Zhai, H; Zhang, S	1
Condon, RE; Fabian, TC; Nichols, RL; Sirinek, KR; Walker, AP; White, PW; Wilson, SE	1
Appleman, MD; Berne, TV; Gill, MA; Heseltine, PN; Yellin, AE	1
Iaconis, JP; Nadler, HL; Pitkin, DH; Sheikh, W	1
Wilson, SE	1
Berman, SJ; Farkas, SA; Geckler, RW; Sieger, B	1
Battles, A; Liu, QF; Liu, W; Louie, A; Miller, DA; Miller, MH; Sucke, AC	1
Aleksandrova, IA; Grudinina, SA; Rezvan, SP; Sidorenko, SV; Sterkhova, GV	1
Cross, AS; Marre, R; Rukavina, T; Trautmann, M; Zick, R	1
Faulkner, K; Wilson, SE	1
Sieger, B	1
Bingen, E; Bonacorsi, S; Fitoussi, F; Lhopital, S	1
Ljungberg, B; Nilsson-Ehle, I; Nyhlén, A; Odenholt, I	1
Jones, RN; Rhomberg, PR	1
Cook, FV; Gavin, PJ; Peterson, LR; Suseno, MT; Thomson, RB	1
Jones, DP; Kink, RJ; Lau, KK	1
Boucher, AN; Lewis, RE; Melnick, DA; Schilling, AN; Tam, VH	1
Abe, M; Araki, M; Horimi, T; Nasu, Y; Ono, N; Takahashi, I	1
Blumer, JL; Konstan, MW; Melnick, D; Saiman, L	1
Balke, B; Häussler, S; Hogardt, M; Hoy, L; Schmoldt, S; Weissbrodt, H	1
Adam, HJ; Laing, N; Mayer, M; Zhanel, GG	1
Arima, H; Hoshitani, K; Ikeda, N; Kobayashi, K; Nakamoto, H; Okada, H; Okada, S; Shoda, J; Sugahara, S; Suzuki, H; Takane, Y; Uchida, K	1
Barbetseas, J; Papathanasiou, S; Rigopoulos, A; Rizos, I; Stefanadis, C; Tsiodras, S	1
Bauernfeind, A; Fehling, M; Griese, M; Kappler, M; Latzin, P; Reinhardt, D	1
Akova, M; Altun, B; Gürkan Aydin, N; Hasçelik, G; Metan, G; Zarakolu, P	1
Dodd, ME; Jones, AM; Webb, AK; Weidmann, A	1
Drusano, GL; Fregeau, C; Kulawy, R; Liu, W; Louie, A	1
Church, AC; Foweraker, J; Parmer, J; Sivasothy, P	1
Boni, V; Braccini, G; Braggion, C; Campana, S; Festini, F; Galici, V; Neri, AS; Taccetti, G; Trevisan, F; Zavataro, L	1
Eagye, KJ; Kuti, JL; Nicasio, AM; Nicolau, DP; Palter, M; Pepe, J; Shore, E	1
Brown, D; Drusano, GL; Fikes, S; Liu, W; Louie, A	1
Kemper, AL; Young, DC; Zobell, JT	1
Fusté, E; Gainza, E; López-Jiménez, L; Segura, C; Viñas, M; Vinuesa, T	1
Eberl, T; Jung, JS; Kostrzewa, M; Lange, C; Schubert, S; Sparbier, K; Wieser, A	1
Baek, JY; Cho, SY; Chung, DR; Kang, CI; Kim, J; Kim, SH; Ko, KS; Peck, KR; Song, JH	1
Charlton-Ouw, KM; Gulbis, BE; Koehler, TM; Kubrusly, F; Leake, SS; Safi, HJ; Sandhu, HK; Swick, MC	1
Buyck, JM; Tulkens, PM; Van Bambeke, F	1
Gholipourmalekabadi, M; Hashemi, A; Mozafari, M; Rostami, A; Sameni, M; Zamani, F	1
Brul, S; Feng, Y; Jonker, MJ; Moustakas, I; Ter Kuile, BH	1
Banerjee, R; Boyce, TG; Cunningham, SA; Hasassri, ME; Jeraldo, PR; Kaye, KS; Norgan, AP; Patel, R; Pogue, JM; Weissman, SJ	1
Acke, M; Coenye, T; Cools, F; Cos, P; Gielis, J; Van Acker, H	1
Akeda, Y; Hagiya, H; Takimoto, K; Tanaka, T; Tomono, K; Yamamoto, N; Yoshida, H	1
Baker, SM; Giatpaiboon, S; LiPuma, JJ; Narayanaswamy, VP; Townsend, SM; Wiesmann, WP	1
Goodlet, KJ; Nailor, MD; Nicolau, DP	1
Maura, D; Rahme, LG	1
Engel, J; Haagensen, J; Huang, L; Spormann, AM; Verotta, D; Yang, K	1
Abreu Ferreira, PM; de Oliveira, SD; Donamore, BK; Gallo, SW; Sanchez Ferreira, CA	1
Avery, LM; DeRonde, KJ; Kuti, JL; Motos, A; Mullane, EM; Nicolau, DP	1
Avery, LM; Nicolau, DP; Sutherland, CA	1
Archetti, M; Baumgartner, M; Kümmerli, R; Mignot, I; Rezzoagli, C	1
Bostrom, MP; Carli, AV; Levack, AE; Miller, AO; Turajane, K; Wellman, DS; Yang, X	1
Ahn, J; Dawan, J; Kim, JC	1
Bostrom, MP; Carli, AV; Driscoll, DA; Levack, AE; Miller, AO; Turajane, K; Wellman, DS; Yang, X	1
Darlow, C; Das, S; Farrington, N; Greenberg, R; Hope, W; Hornik, C; Jimenez-Valverde, A; Johnson, A; McEntee, L; Schwartz, J; Unsworth, J	1
Daneman, N; Elligsen, M; Katz, K; Lam, PW; Lo, J; MacFadden, D; Teitelbaum, D; Vermeiren, C	1
Ardebili, A; Bagheri, H; Goharrizi, MASB; Hjimohammadi, A; Izanloo, A; Jamali, A; Shahri, FN	1
Bakkaloglu, Z; Demirbas, Z; Dizbay, M; Ozger, HS; Suzuk-Yildiz, S	1
Abulaila, A; Aktas, Z; Cantón, R; Díez-Aguilar, M; Erdem, F; Kayacan, C; Morosini, MI; Oksuz, L; Oncul, O	1
Baccaro, M; Bakker, W; Murali, A; Rietjens, IMCM; van Ravenzwaay, B; Wang, J; Zhang, N; Zheng, W	1
Gu, H; Tong, K; Wei, J; Zhou, S	1
Caljon, B; Crombé, F; De Geyter, D; Demuyser, T; Janssen, T; Muyldermans, A; Piérard, D; Seyler, L; Vanstokstraeten, R; Wybo, I	1

Reviews

4 review(s) available for tobramycin and meropenem

Article	Year
Left-sided endocarditis caused by Pseudomonas aeruginosa: successful treatment with meropenem and tobramycin. Diagnostic microbiology and infectious disease, 2003, Volume: 47, Issue:2 Topics: Adult; Anti-Bacterial Agents; Drug Therapy, Combination; Endocarditis, Bacterial; Humans; Male; Meropenem; Pseudomonas aeruginosa; Pseudomonas Infections; Thienamycins; Tobramycin	2003
Prosthetic valve endocarditis due to Acinetobacter spp: a rare case and literature review. The American journal of the medical sciences, 2007, Volume: 333, Issue:3 Topics: Acinetobacter; Acinetobacter Infections; Aged; Anti-Bacterial Agents; Cross Infection; Echocardiography, Transesophageal; Endocarditis, Bacterial; Heart Valve Prosthesis; Heart Valve Prosthesis Implantation; Humans; Male; Meropenem; Reoperation; Thienamycins; Tobramycin	2007
Mediastinal abscess after lung transplantation secondary to Burkholderia gladioli infection. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2009, Volume: 28, Issue:5 Topics: Abscess; Adult; Anti-Bacterial Agents; Burkholderia gladioli; Burkholderia Infections; Combined Modality Therapy; Cystic Fibrosis; Diagnosis, Differential; Drainage; Drug Therapy, Combination; Humans; Infusions, Intravenous; Lung Transplantation; Male; Mediastinal Diseases; Meropenem; Opportunistic Infections; Postoperative Complications; Thienamycins; Tobramycin; Tomography, X-Ray Computed	2009
Non-nosocomial healthcare-associated left-sided Pseudomonas aeruginosa endocarditis: a case report and literature review. BMC infectious diseases, 2016, 08-20, Volume: 16, Issue:1 Topics: Aged; Anti-Bacterial Agents; Aortic Valve; Drug Therapy, Combination; Echocardiography, Transesophageal; Endocarditis; Endocarditis, Bacterial; Foramen Ovale, Patent; Heart Valve Prosthesis; Heart Valve Prosthesis Implantation; Humans; Intermittent Urethral Catheterization; Magnetic Resonance Imaging; Male; Meropenem; Pseudomonas aeruginosa; Pseudomonas Infections; Thienamycins; Tobramycin; Ultrasonography, Doppler	2016

Trials

7 trial(s) available for tobramycin and meropenem

Article	Year
Meropenem versus tobramycin plus clindamycin for treatment of intraabdominal infections: results of a prospective, randomized, double-blind clinical trial. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1995, Volume: 21, Issue:3 Topics: Abdomen; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Clindamycin; Diarrhea; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Meropenem; Middle Aged; Prospective Studies; Thienamycins; Tobramycin	1995
Meropenem versus tobramycin with clindamycin in the antibiotic management of patients with advanced appendicitis. Journal of the American College of Surgeons, 1996, Volume: 182, Issue:5 Topics: Adult; Anti-Bacterial Agents; Appendicitis; Clindamycin; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Intestinal Perforation; Length of Stay; Male; Meropenem; Rupture, Spontaneous; Thienamycins; Time Factors; Tobramycin	1996
Results of a randomized, multicenter trial of meropenem versus clindamycin/tobramycin for the treatment of intra-abdominal infections. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1997, Volume: 24 Suppl 2 Topics: Abdominal Abscess; Adolescent; Adult; Aged; Anti-Bacterial Agents; Appendicitis; Bacteria, Anaerobic; Clindamycin; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Gram-Negative Aerobic Bacteria; Gram-Positive Bacteria; Humans; Male; Meropenem; Middle Aged; Thienamycins; Tobramycin; Treatment Outcome	1997
Empiric treatment of hospital-acquired lower respiratory tract infections with meropenem or ceftazidime with tobramycin: a randomized study. Meropenem Lower Respiratory Infection Group. Critical care medicine, 1997, Volume: 25, Issue:10 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Ceftazidime; Cephalosporins; Cross Infection; Drug Therapy, Combination; Female; Humans; Male; Meropenem; Middle Aged; Prospective Studies; Respiratory Tract Infections; Thienamycins; Time Factors; Tobramycin	1997
Impact an anatomical site on bacteriological and clinical outcome in the management of intra-abdominal infections. The American surgeon, 1998, Volume: 64, Issue:5 Topics: Adult; Aged; Anti-Bacterial Agents; Appendicitis; Bacterial Infections; Bacteriological Techniques; Cause of Death; Cilastatin; Clindamycin; Combined Modality Therapy; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Imipenem; Male; Meropenem; Middle Aged; Peritonitis; Risk Factors; Survival Rate; Thienamycins; Tobramycin; Treatment Outcome	1998
The efficacy and safety of meropenem and tobramycin vs ceftazidime and tobramycin in the treatment of acute pulmonary exacerbations in patients with cystic fibrosis. Chest, 2005, Volume: 128, Issue:4 Topics: Adolescent; Adult; Anti-Bacterial Agents; Burkholderia cepacia; Burkholderia Infections; Ceftazidime; Child; Child, Preschool; Cystic Fibrosis; Disease Progression; Drug Therapy, Combination; Forced Expiratory Volume; Humans; Meropenem; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Function Tests; Sputum; Thienamycins; Tobramycin	2005
Efficacy and safety of intravenous meropenem and tobramycin versus ceftazidime and tobramycin in cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2008, Volume: 7, Issue:2 Topics: Adolescent; Anti-Bacterial Agents; Bacterial Infections; C-Reactive Protein; Ceftazidime; Child; Child, Preschool; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Infusions, Intravenous; Male; Meropenem; Prospective Studies; Thienamycins; Tobramycin; Treatment Outcome	2008

Other Studies

110 other study(ies) available for tobramycin and meropenem

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Clinical prediction tool to identify patients with Pseudomonas aeruginosa respiratory tract infections at greatest risk for multidrug resistance. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:2 Topics: Adult; Anti-Bacterial Agents; Case-Control Studies; Drug Resistance, Multiple, Bacterial; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Predictive Value of Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Retrospective Studies; Risk; Risk Factors	2007
Coproduction of novel 16S rRNA methylase RmtD and metallo-beta-lactamase SPM-1 in a panresistant Pseudomonas aeruginosa isolate from Brazil. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:3 Topics: Amino Acid Sequence; Aminoglycosides; beta-Lactamases; Brazil; Carbapenems; Cloning, Molecular; Drug Resistance, Multiple, Bacterial; Methyltransferases; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Pseudomonas aeruginosa; Pseudomonas Infections	2007
Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4 Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Drug Resistance, Bacterial; Humans; Longitudinal Studies; Pneumonia, Ventilator-Associated; Polymerase Chain Reaction; Pseudomonas aeruginosa; Pseudomonas Infections	2007
First identification of Pseudomonas aeruginosa isolates producing a KPC-type carbapenem-hydrolyzing beta-lactamase. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4 Topics: beta-Lactamases; Carbapenems; Drug Resistance, Bacterial; Hydrolysis; Microbial Sensitivity Tests; Pseudomonas aeruginosa	2007
Spread of extended-spectrum beta-lactamase CTX-M-producing escherichia coli clinical isolates in community and nosocomial environments in Portugal. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6 Topics: Aged; Anti-Bacterial Agents; beta-Lactamases; Community-Acquired Infections; Cross Infection; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Humans; Microbial Sensitivity Tests; Middle Aged; Portugal	2007
Spread in an Italian hospital of a clonal Acinetobacter baumannii strain producing the TEM-92 extended-spectrum beta-lactamase. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6 Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Cross Infection; Humans; Italy; Microbial Sensitivity Tests	2007
Effects of carbapenem exposure on the risk for digestive tract carriage of intensive care unit-endemic carbapenem-resistant Pseudomonas aeruginosa strains in critically ill patients. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6 Topics: Adult; Aged; Anti-Bacterial Agents; beta-Lactam Resistance; Carbapenems; Carrier State; Critical Illness; Endemic Diseases; Female; Gastrointestinal Tract; Humans; Imipenem; Incidence; Intensive Care Units; Male; Middle Aged; Pharynx; Pseudomonas aeruginosa; Pseudomonas Infections; Rectum; Risk Factors	2007
Tigecycline Efflux as a Mechanism for Nonsusceptibility in Acinetobacter baumannii. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6 Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance, Bacterial; Ethidium; Gene Expression Regulation, Bacterial; Humans; Membrane Transport Proteins; Microbial Sensitivity Tests; Minocycline; Molecular Sequence Data; Sequence Analysis, DNA; Tigecycline	2007
Enterobacteriaceae bloodstream infections: presence of integrons, risk factors, and outcome. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7 Topics: Bacteremia; Community-Acquired Infections; Cross Infection; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Enterobacteriaceae Infections; Gene Transfer, Horizontal; Humans; Infectious Disease Transmission, Professional-to-Patient; Integrons; Microbial Sensitivity Tests; Nucleic Acid Amplification Techniques; Polymerase Chain Reaction; Prospective Studies; Risk Factors; Sequence Analysis, DNA; Treatment Outcome	2007
Influence of high mutation rates on the mechanisms and dynamics of in vitro and in vivo resistance development to single or combined antipseudomonal agents. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7 Topics: Animals; Anti-Bacterial Agents; Ceftazidime; Ciprofloxacin; Disease Models, Animal; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; Female; Humans; In Vitro Techniques; Lung; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Mutation; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2007
Characterization of an integron carrying blaIMP-1 and a new aminoglycoside resistance gene, aac(6')-31, and its dissemination among genetically unrelated clinical isolates in a Brazilian hospital. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7 Topics: Acinetobacter; Amino Acid Sequence; Aminoglycosides; Anti-Bacterial Agents; Base Sequence; Brazil; Codon, Terminator; Cross Infection; Drug Resistance, Multiple, Bacterial; Gene Transfer, Horizontal; Genes, Bacterial; Hospitals; Humans; Integrons; Microbial Sensitivity Tests; Molecular Sequence Data; Open Reading Frames; Plasmids; Pseudomonas putida; Transcription, Genetic	2007
Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:9 Topics: Bacterial Proteins; Base Sequence; beta-Lactamases; Carrier Proteins; Cloning, Molecular; DNA, Bacterial; Drug Resistance, Bacterial; Enterobacter cloacae; Enterobacteriaceae Infections; Genes, MDR; Genetic Vectors; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Porins	2007
Molecular epidemiology and mechanisms of carbapenem resistance in Pseudomonas aeruginosa isolates from Spanish hospitals. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12 Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Carbapenems; Chromosomes, Bacterial; Cross Infection; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Integrons; Molecular Epidemiology; Molecular Sequence Data; Mutation; Plasmids; Polymerase Chain Reaction; Porins; Pseudomonas aeruginosa; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Spain	2007
IMP-15-producing Pseudomonas aeruginosa strain isolated in a U.S. medical center: a recent arrival from Mexico. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:6 Topics: Adult; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Hospitals; Humans; Imipenem; Kentucky; Male; Mexico; Pseudomonas aeruginosa; United States	2008
Presence of plasmid-mediated quinolone resistance in Klebsiella pneumoniae isolates possessing blaKPC in the United States. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:7 Topics: Aged; Bacterial Proteins; Base Sequence; beta-Lactamases; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Genes, Bacterial; Humans; Klebsiella Infections; Klebsiella pneumoniae; Male; Microbial Sensitivity Tests; Molecular Epidemiology; Plasmids; Quinolones; United States	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Characterization of the carbapenem-hydrolyzing oxacillinase oxa-58 in an Acinetobacter genospecies 3 clinical isolate. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8 Topics: Acinetobacter; Acinetobacter Infections; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; beta-Lactamases; Carbapenems; Humans; Imipenem; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Sequence Analysis, DNA	2008
Spread of OXA-48-positive carbapenem-resistant Klebsiella pneumoniae isolates in Istanbul, Turkey. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8 Topics: Bacterial Proteins; beta-Lactamases; Carbapenems; Cross Infection; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Models, Genetic; Turkey	2008
VIM-15 and VIM-16, two new VIM-2-like metallo-beta-lactamases in Pseudomonas aeruginosa isolates from Bulgaria and Germany. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8 Topics: Amino Acid Substitution; Bacterial Proteins; beta-Lactamases; Bulgaria; Catalysis; Germany; Hydrolysis; Isoenzymes; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Pseudomonas aeruginosa; Sequence Analysis, DNA	2008
Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:9 Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; beta-Lactamases; Drug Resistance, Bacterial; Endemic Diseases; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; New York City; Sequence Analysis, DNA	2008
Characterization of the new metallo-beta-lactamase VIM-13 and its integron-borne gene from a Pseudomonas aeruginosa clinical isolate in Spain. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:10 Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; beta-Lactam Resistance; beta-Lactamases; Cloning, Molecular; DNA Primers; DNA, Bacterial; Genes, Bacterial; Genetic Variation; Humans; Imipenem; Integrons; Kinetics; Meropenem; Molecular Sequence Data; Phylogeny; Pseudomonas aeruginosa; Pseudomonas Infections; Recombinant Proteins; Sequence Homology, Amino Acid; Spain; Thienamycins	2008
Antimicrobial studies with the Pseudomonas aeruginosa two-allele library require caution. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:10 Topics: Alleles; DNA Transposable Elements; DNA, Bacterial; Drug Resistance, Bacterial; Gene Library; Genes, Bacterial; Humans; Microbial Sensitivity Tests; Mutation; Pseudomonas aeruginosa; Pyocyanine	2008
Genetic basis of multidrug resistance in Acinetobacter baumannii clinical isolates at a tertiary medical center in Pennsylvania. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:11 Topics: Academic Medical Centers; Acinetobacter baumannii; Acinetobacter Infections; Amikacin; Base Sequence; beta-Lactamases; Cross Infection; DNA Primers; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Genes, Bacterial; Humans; Microbial Sensitivity Tests; Molecular Epidemiology; Pennsylvania; Polymerase Chain Reaction	2008
KPC-2-producing Enterobacter cloacae and pseudomonas putida coinfection in a liver transplant recipient. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:1 Topics: Anti-Bacterial Agents; beta-Lactamases; Enterobacter cloacae; Female; Humans; Liver Transplantation; Microbial Sensitivity Tests; Middle Aged; Pseudomonas putida; RNA, Ribosomal, 16S	2009
Detection of the pandemic O25-ST131 human virulent Escherichia coli CTX-M-15-producing clone harboring the qnrB2 and aac(6')-Ib-cr genes in a dog. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:1 Topics: Animals; Anti-Bacterial Agents; Dogs; Drug Resistance, Bacterial; Escherichia coli; Genes, Bacterial; Humans; Plasmids; Virulence	2009
Codetection of blaOXA-23-like gene (blaOXA-133) and blaOXA-58 in Acinetobacter radioresistens: report from the SENTRY antimicrobial surveillance program. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:2 Topics: Acinetobacter; Anti-Bacterial Agents; beta-Lactamases; Drug Resistance, Bacterial; Molecular Sequence Data; Plasmids; Population Surveillance; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic	2009
Carbapenem resistance among Pseudomonas aeruginosa strains from India: evidence for nationwide endemicity of multiple metallo-beta-lactamase clones (VIM-2, -5, -6, and -11 and the newly characterized VIM-18). Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:3 Topics: Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; beta-Lactamases; Carbapenems; Drug Resistance, Bacterial; Humans; India; Microbial Sensitivity Tests; Molecular Sequence Data; Prevalence; Pseudomonas aeruginosa; Ribotyping	2009
First organisms with acquired metallo-beta-lactamases (IMP-13, IMP-22, and VIM-2) reported in Austria. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:5 Topics: Austria; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Pseudomonas aeruginosa; Pseudomonas Infections; Sequence Analysis, DNA	2009
AAC(6')-Iaf, a novel aminoglycoside 6'-N-acetyltransferase from multidrug-resistant Pseudomonas aeruginosa clinical isolates. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:6 Topics: Acetylation; Acetyltransferases; Aminoglycosides; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Integrons; Microbial Sensitivity Tests; Pseudomonas aeruginosa	2009
AbaR5, a large multiple-antibiotic resistance region found in Acinetobacter baumannii. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:6 Topics: Acinetobacter baumannii; Base Sequence; DNA Transposable Elements; Drug Resistance, Multiple, Bacterial; Molecular Sequence Data; Multigene Family; Polymerase Chain Reaction	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Complete nucleotide sequences of plasmids pEK204, pEK499, and pEK516, encoding CTX-M enzymes in three major Escherichia coli lineages from the United Kingdom, all belonging to the international O25:H4-ST131 clone. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:10 Topics: beta-Lactamases; Computational Biology; Escherichia coli; Models, Genetic; Molecular Sequence Data; Open Reading Frames; Plasmids; United Kingdom	2009
Nosocomial spread of colistin-only-sensitive sequence type 235 Pseudomonas aeruginosa isolates producing the extended-spectrum beta-lactamases GES-1 and GES-5 in Spain. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:11 Topics: Anti-Bacterial Agents; Base Sequence; beta-Lactamases; Colistin; Cross Infection; Humans; Molecular Sequence Data; Pseudomonas aeruginosa	2009
Detection of the novel extended-spectrum beta-lactamase OXA-161 from a plasmid-located integron in Pseudomonas aeruginosa clinical isolates from Spain. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:12 Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Clavulanic Acid; Gentamicins; Humans; Imipenem; Integrons; Meropenem; Molecular Sequence Data; Penicillanic Acid; Piperacillin; Plasmids; Pseudomonas aeruginosa; Pseudomonas Infections; Spain; Tazobactam; Thienamycins	2009
In vivo efficacy of 1- and 2-gram human simulated prolonged infusions of doripenem against Pseudomonas aeruginosa. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:10 Topics: Animals; Anti-Bacterial Agents; Carbapenems; Doripenem; Drug Administration Schedule; Female; Humans; Mice; Pseudomonas aeruginosa; Pseudomonas Infections	2009
Klebsiella pneumoniae AcrAB efflux pump contributes to antimicrobial resistance and virulence. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1 Topics: Animals; Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Culture Media; Defensins; DNA, Bacterial; Drug Resistance, Bacterial; Genotype; Humans; Klebsiella Infections; Klebsiella pneumoniae; Lipopolysaccharides; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Phenotype; Plasmids; Polymyxin B; Polysaccharides; Repressor Proteins; RNA, Bacterial	2010
In vitro potency of CXA-101, a novel cephalosporin, against Pseudomonas aeruginosa displaying various resistance phenotypes, including multidrug resistance. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1 Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Cephalosporins; Child; Child, Preschool; Cross Infection; Drug Combinations; Drug Resistance, Multiple, Bacterial; Humans; Infant; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Pseudomonas aeruginosa; Tazobactam; Young Adult	2010
Activity of a new antipseudomonal cephalosporin, CXA-101 (FR264205), against carbapenem-resistant and multidrug-resistant Pseudomonas aeruginosa clinical strains. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:2 Topics: Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Cephalosporins; Drug Resistance, Multiple, Bacterial; Humans; Isoelectric Focusing; Microbial Sensitivity Tests; Polymerase Chain Reaction; Pseudomonas aeruginosa; Pseudomonas Infections	2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Acinetobacter baumannii increases tolerance to antibiotics in response to monovalent cations. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:3 Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Proteins; Cations, Monovalent; Culture Media; Drug Resistance, Bacterial; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Humans; Microbial Sensitivity Tests; Oligonucleotide Array Sequence Analysis; Proteomics; Sodium Chloride; Virulence Factors	2010
Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5 Topics: Bacterial Outer Membrane Proteins; Bacterial Proteins; beta-Lactamases; Cystic Fibrosis; Drug Resistance, Bacterial; Drug Resistance, Multiple; Electrophoresis, Gel, Pulsed-Field; Humans; Membrane Transport Proteins; Mutation; Porins; Pseudomonas aeruginosa; Pseudomonas Infections; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation	2010
Genetic basis of multidrug resistance in Acinetobacter clinical isolates in Taiwan. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5 Topics: Acinetobacter baumannii; Acinetobacter Infections; Aminoglycosides; beta-Lactamases; Carbapenems; Cephalosporins; DNA Gyrase; Drug Resistance, Bacterial; Drug Resistance, Multiple; Fluoroquinolones; Humans; Taiwan	2010
Molecular characterization of beta-lactamase genes and their genetic structures in Acinetobacter genospecies 3 isolates in Taiwan. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:6 Topics: Acinetobacter; Acinetobacter Infections; beta-Lactam Resistance; beta-Lactamases; Cephalosporinase; Gene Transfer, Horizontal; Genes, Bacterial; Humans; In Vitro Techniques; Integrons; Microbial Sensitivity Tests; Molecular Epidemiology; Molecular Sequence Data; Phylogeny; Taiwan	2010
In vitro activity of the aminoglycoside antibiotic arbekacin against Acinetobacter baumannii-calcoaceticus isolated from war-wounded patients at Walter Reed Army Medical Center. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:7 Topics: Acinetobacter baumannii; Aminoglycosides; Anti-Bacterial Agents; Carbapenems; Dibekacin; Hospitals, Military; Humans; Microbial Sensitivity Tests; Warfare	2010
First survey of metallo-beta-lactamases in clinical isolates of Pseudomonas aeruginosa in a German university hospital. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:8 Topics: Anti-Bacterial Agents; beta-Lactamases; Ceftazidime; Drug Resistance, Bacterial; Germany; Hospitals, University; Humans; Imipenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections	2010
Foreign travel is a major risk factor for colonization with Escherichia coli producing CTX-M-type extended-spectrum beta-lactamases: a prospective study with Swedish volunteers. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:9 Topics: Adolescent; Adult; Aged; Aged, 80 and over; beta-Lactamases; Child; Child, Preschool; Escherichia coli; Escherichia coli Infections; Female; Humans; Male; Middle Aged; Prospective Studies; Risk Factors; Sweden; Travel; White People; Young Adult	2010
Frequency of spontaneous resistance to fosfomycin combined with different antibiotics in Pseudomonas aeruginosa. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:11 Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Fosfomycin; Mutation; Pseudomonas aeruginosa	2010
In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:12 Topics: Acinetobacter baumannii; Acinetobacter Infections; Bacterial Proteins; Carbapenems; Drug Resistance, Bacterial; Fatal Outcome; Humans; Male; Middle Aged; Molecular Sequence Data; Mutation, Missense; Reverse Transcriptase Polymerase Chain Reaction	2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR. European journal of medicinal chemistry, 2011, Volume: 46, Issue:1 Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics	2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. Bioorganic & medicinal chemistry, 2013, Dec-01, Volume: 21, Issue:23 Topics: Anti-Infective Agents; Bacterial Infections; Drug Resistance, Multiple; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Imidazoles; Microbial Sensitivity Tests; Mycoses; Oximes	2013
Thiol activated prodrugs of sulfur dioxide (SO2) as MRSA inhibitors. Bioorganic & medicinal chemistry letters, 2015, Jul-01, Volume: 25, Issue:13 Topics: Anti-Bacterial Agents; Drug Design; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Prodrugs; Staphylococcal Infections; Structure-Activity Relationship; Sulfhydryl Compounds; Sulfur Dioxide	2015
Hybrid Antibiotic Overcomes Resistance in P. aeruginosa by Enhancing Outer Membrane Penetration and Reducing Efflux. Journal of medicinal chemistry, 2016, 09-22, Volume: 59, Issue:18 Topics: Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Humans; Moxifloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2016
Heterocyclyl Tetracyclines. 1. 7-Trifluoromethyl-8-Pyrrolidinyltetracyclines: Potent, Broad Spectrum Antibacterial Agents with Enhanced Activity against Pseudomonas aeruginosa. Journal of medicinal chemistry, 2017, 03-23, Volume: 60, Issue:6 Topics: Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Halogenation; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Pyrrolidinones; Tetracycline Resistance; Tetracyclines	2017
Amphiphilic Tobramycin-Lysine Conjugates Sensitize Multidrug Resistant Gram-Negative Bacteria to Rifampicin and Minocycline. Journal of medicinal chemistry, 2017, 05-11, Volume: 60, Issue:9 Topics: Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Hemolysis; Lysine; Microbial Sensitivity Tests; Minocycline; Models, Biological; Rifampin; Tobramycin	2017
Design, Synthesis, and Properties of a Potent Inhibitor of Pseudomonas aeruginosa Deacetylase LpxC. Journal of medicinal chemistry, 2017, 06-22, Volume: 60, Issue:12 Topics: Amidohydrolases; Animals; Anti-Bacterial Agents; Chemistry Techniques, Synthetic; Crystallography, X-Ray; Drug Design; Drug Evaluation, Preclinical; Drug Resistance, Multiple, Bacterial; Enzyme Inhibitors; Female; Hep G2 Cells; Humans; K562 Cells; Mice, Inbred BALB C; Microbial Sensitivity Tests; Molecular Docking Simulation; Pseudomonas aeruginosa; Pseudomonas Infections; Structure-Activity Relationship	2017
Heterodimeric Rifampicin-Tobramycin conjugates break intrinsic resistance of Pseudomonas aeruginosa to doxycycline and chloramphenicol in vitro and in a Galleria mellonella in vivo model. European journal of medicinal chemistry, 2019, Jul-15, Volume: 174 Topics: Animals; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Chloramphenicol; Doxycycline; Drug Resistance, Multiple, Bacterial; Drug Synergism; HEK293 Cells; Hep G2 Cells; Humans; Membrane Transport Proteins; Microbial Sensitivity Tests; Molecular Structure; Moths; Pseudomonas aeruginosa; Rifampin; Swine; Tobramycin	2019
Design, synthesis, and biological evaluation of 3-amino-2-oxazolidinone derivatives as potent quorum-sensing inhibitors of Pseudomonas aeruginosa PAO1. European journal of medicinal chemistry, 2020, May-15, Volume: 194 Topics: Anti-Bacterial Agents; Biofilms; Dose-Response Relationship, Drug; Drug Design; Microbial Sensitivity Tests; Molecular Structure; Oxazolidinones; Pseudomonas aeruginosa; Quorum Sensing; Structure-Activity Relationship	2020
Amphiphilic cyclic peptide [W European journal of medicinal chemistry, 2022, May-05, Volume: 235 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Gram-Negative Bacteria; Gram-Positive Bacteria; Meropenem; Microbial Sensitivity Tests; Peptides, Cyclic; Pseudomonas aeruginosa	2022
Design, synthesis and activity against drug-resistant bacteria evaluation of C-20, C-23 modified 5-O-mycaminosyltylonolide derivatives. European journal of medicinal chemistry, 2022, Aug-05, Volume: 238 Topics: Animals; Anti-Bacterial Agents; Gram-Negative Bacteria; Gram-Positive Bacteria; Leucomycins; Mice; Microbial Sensitivity Tests; Structure-Activity Relationship	2022
Comparison of antibacterial activities of meropenem and six other antimicrobials against Pseudomonas aeruginosa isolates from North American studies and clinical trials. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1997, Volume: 24 Suppl 2 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Proteins; beta-Lactamases; Ceftazidime; Cephalosporins; Ciprofloxacin; Clinical Trials as Topic; Drug Resistance, Microbial; Gentamicins; Humans; Imipenem; Isoelectric Focusing; Meropenem; Microbial Sensitivity Tests; Penicillins; Piperacillin; Pseudomonas aeruginosa; Thienamycins; Tobramycin	1997
Predictive value of several signs of infection as surrogate markers for mortality in a neutropenic guinea pig model of Pseudomonas aeruginosa sepsis. Laboratory animal science, 1997, Volume: 47, Issue:6 Topics: Animals; Anti-Bacterial Agents; Biomarkers; Ceftazidime; Cephalosporins; Diarrhea; Disease Models, Animal; Female; Guinea Pigs; Imipenem; Meropenem; Movement Disorders; Neutropenia; Predictive Value of Tests; Pseudomonas Infections; Regression Analysis; Respiration; Thienamycins; Time Factors; Tobramycin; Weight Loss	1997
[Comparative activity of meropenem and other antibiotics against the pathogens of nosocomial infections]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1998, Volume: 43, Issue:1 Topics: Anti-Bacterial Agents; Cephalosporins; Cross Infection; Drug Therapy, Combination; Gentamicins; Gram-Negative Bacteria; Gram-Positive Bacteria; Imipenem; Meropenem; Microbial Sensitivity Tests; Thienamycins; Tobramycin	1998
Antibiotic-induced release of endotoxin: in-vitro comparison of meropenem and other antibiotics. The Journal of antimicrobial chemotherapy, 1998, Volume: 41, Issue:2 Topics: Anti-Bacterial Agents; Antibodies, Monoclonal; Ceftazidime; Ciprofloxacin; Enzyme-Linked Immunosorbent Assay; Escherichia coli; Imipenem; Lipopolysaccharides; Meropenem; Microbial Sensitivity Tests; O Antigens; Thienamycins; Tobramycin	1998
Meropenem monotherapy as empiric treatment of nosocomial lower respiratory tract infection. Critical care medicine, 1998, Volume: 26, Issue:8 Topics: Anti-Bacterial Agents; Ceftazidime; Cephalosporins; Critical Illness; Cross Infection; Drug Therapy, Combination; Humans; Meropenem; Pneumonia, Bacterial; Severity of Illness Index; Thienamycins; Tobramycin; Treatment Outcome	1998
Comparative in vitro activities of meropenem, imipenem, temocillin, piperacillin, and ceftazidime in combination with tobramycin, rifampin, or ciprofloxacin against Burkholderia cepacia isolates from patients with cystic fibrosis. Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:2 Topics: Burkholderia cepacia; Burkholderia Infections; Ceftazidime; Ciprofloxacin; Cystic Fibrosis; Drug Synergism; Drug Therapy, Combination; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Penicillins; Piperacillin; Rifampin; Thienamycins; Tobramycin	1999
Bactericidal effect of combinations of antibiotic and antineoplastic agents against Staphylococcus aureus and Escherichia coli. Chemotherapy, 2002, Volume: 48, Issue:2 Topics: Anti-Bacterial Agents; Antineoplastic Agents; Ceftazidime; Cephalosporins; Doxorubicin; Drug Interactions; Drug Therapy, Combination; Escherichia coli; Escherichia coli Infections; Etoposide; Fluorouracil; Meropenem; Microbial Sensitivity Tests; Staphylococcal Infections; Staphylococcus aureus; Thienamycins; Tobramycin	2002
Antimicrobial spectrum of activity for meropenem and nine broad spectrum antimicrobials: report from the MYSTIC Program (2002) in North America. Diagnostic microbiology and infectious disease, 2003, Volume: 47, Issue:1 Topics: Anti-Bacterial Agents; Aztreonam; Cefepime; Cephalosporins; Ciprofloxacin; Drug Resistance, Bacterial; Drug Resistance, Multiple; Female; Gentamicins; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Male; Meropenem; Microbial Sensitivity Tests; North America; Sensitivity and Specificity; Thienamycins; Tobramycin	2003
Myoclonus associated with intraperitoneal imipenem. Pediatric nephrology (Berlin, Germany), 2004, Volume: 19, Issue:6 Topics: Anti-Bacterial Agents; Ascitic Fluid; Child, Preschool; Enterobacter cloacae; Enterobacteriaceae Infections; Humans; Imipenem; Infusions, Parenteral; Kidney Failure, Chronic; Male; Medication Errors; Meropenem; Myoclonus; Peritoneal Dialysis, Continuous Ambulatory; Peritonitis; Thienamycins; Tobramycin	2004
Novel approach to characterization of combined pharmacodynamic effects of antimicrobial agents. Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:11 Topics: Algorithms; Colony Count, Microbial; Data Interpretation, Statistical; Drug Interactions; Drug Resistance, Multiple, Bacterial; Drug Synergism; Drug Therapy, Combination; Meropenem; Microbial Sensitivity Tests; Pilot Projects; Pseudomonas aeruginosa; Thienamycins; Tobramycin	2004
[Antimicrobial susceptibility of Pseudomonas aeruginosa isolated at Kochi Municipal Central Hospital in the last 3 years]. The Japanese journal of antibiotics, 2004, Volume: 57, Issue:5 Topics: Amikacin; Anti-Bacterial Agents; Ceftazidime; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Piperacillin; Pseudomonas aeruginosa; Pseudomonas Infections; Thienamycins; Tobramycin	2004
Evaluation of the E test for the assessment of synergy of antibiotic combinations against multiresistant Pseudomonas aeruginosa isolates from cystic fibrosis patients. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2006, Volume: 25, Issue:1 Topics: Anti-Bacterial Agents; Ceftazidime; Cystic Fibrosis; Drug Resistance, Multiple; Drug Synergism; Drug Therapy, Combination; Humans; Meropenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Reproducibility of Results; Thienamycins; Tobramycin	2006
Mutant prevention concentrations of levofloxacin alone and in combination with azithromycin, ceftazidime, colistin (Polymyxin E), meropenem, piperacillin-tazobactam, and tobramycin against Pseudomonas aeruginosa. Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:6 Topics: Anti-Bacterial Agents; Azithromycin; Ceftazidime; Colistin; Dose-Response Relationship, Drug; Drug Synergism; In Vitro Techniques; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Mutation; Ofloxacin; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Thienamycins; Tobramycin	2006
Efficacy and safety of meropenem plus tobramycin followed by meropenem plus vancomycin for treating peritonitis in patients on continuous ambulatory peritoneal dialysis. Advances in peritoneal dialysis. Conference on Peritoneal Dialysis, 2006, Volume: 22 Topics: Anti-Bacterial Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Meropenem; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Peritonitis; Thienamycins; Tobramycin; Treatment Outcome; Vancomycin	2006
[The frequency of PER-1 type extended spectrum beta-lactamases in nosocomial isolates of Pseudomonas aeruginosa]. Mikrobiyoloji bulteni, 2007, Volume: 41, Issue:3 Topics: Anti-Bacterial Agents; beta-Lactamases; Cross Infection; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Imipenem; Meropenem; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Polymerase Chain Reaction; Pseudomonas aeruginosa; Pseudomonas Infections; Thienamycins; Tobramycin	2007
Successful treatment of cepacia syndrome with combination nebulised and intravenous antibiotic therapy. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2008, Volume: 7, Issue:5 Topics: Adult; Anti-Bacterial Agents; Burkholderia cepacia; Burkholderia Infections; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Meropenem; Nebulizers and Vaporizers; Syndrome; Thienamycins; Tobramycin	2008
Differing effects of combination chemotherapy with meropenem and tobramycin on cell kill and suppression of resistance of wild-type Pseudomonas aeruginosa PAO1 and its isogenic MexAB efflux pump-overexpressed mutant. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:6 Topics: Anti-Bacterial Agents; Area Under Curve; Bacterial Outer Membrane Proteins; Drug Resistance, Bacterial; Drug Therapy, Combination; Membrane Transport Proteins; Meropenem; Microbial Sensitivity Tests; Mutation; Pseudomonas aeruginosa; Thienamycins; Tobramycin	2009
The costs of treatment of early and chronic Pseudomonas aeruginosa infection in cystic fibrosis patients. Journal of chemotherapy (Florence, Italy), 2009, Volume: 21, Issue:2 Topics: Adult; Anti-Bacterial Agents; Ceftazidime; Child, Preschool; Chronic Disease; Ciprofloxacin; Clavulanic Acids; Colistin; Cost of Illness; Cystic Fibrosis; Humans; Meropenem; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Thienamycins; Ticarcillin; Tobramycin	2009
Pharmacodynamic-based clinical pathway for empiric antibiotic choice in patients with ventilator-associated pneumonia. Journal of critical care, 2010, Volume: 25, Issue:1 Topics: Adult; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Critical Pathways; Drug Administration Schedule; Drug Therapy, Combination; Female; Hospital Mortality; Humans; Intensive Care Units; Length of Stay; Male; Meropenem; Microbial Sensitivity Tests; Middle Aged; Monte Carlo Method; Observation; Pneumonia, Ventilator-Associated; Prospective Studies; Pseudomonas aeruginosa; Pseudomonas Infections; Thienamycins; Tobramycin; Treatment Outcome; Vancomycin; Young Adult	2010
Impact of meropenem in combination with tobramycin in a murine model of Pseudomonas aeruginosa pneumonia. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:6 Topics: Animals; Anti-Bacterial Agents; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Female; Humans; Lung; Meropenem; Mice; Microbial Sensitivity Tests; Models, Theoretical; Pneumonia, Bacterial; Pseudomonas aeruginosa; Thienamycins; Tobramycin; Treatment Outcome	2013
The use of doripenem in pediatric cystic fibrosis patients in case of meropenem shortages. Pediatric pulmonology, 2014, Volume: 49, Issue:3 Topics: Adolescent; Anti-Bacterial Agents; Burkholderia cenocepacia; Burkholderia Infections; Carbapenems; Child; Cystic Fibrosis; Disease Progression; Doripenem; Drug Therapy, Combination; Female; Gram-Negative Bacterial Infections; Humans; Infusions, Intravenous; Meropenem; Pseudomonas aeruginosa; Pseudomonas Infections; Pseudomonas stutzeri; Rhodospirillaceae; Thienamycins; Tobramycin; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination	2014
Carbapenem-resistance mechanisms of multidrug-resistant Pseudomonas aeruginosa. Journal of medical microbiology, 2013, Volume: 62, Issue:Pt 9 Topics: Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; Base Sequence; Carbapenems; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Dipeptides; Drug Resistance, Multiple, Bacterial; Drug Synergism; Membrane Transport Proteins; Meropenem; Microbial Sensitivity Tests; Molecular Sequence Data; Porins; Pseudomonas aeruginosa; Thienamycins; Tobramycin	2013
Rapid detection of antibiotic resistance based on mass spectrometry and stable isotopes. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2014, Volume: 33, Issue:6 Topics: Amino Acids; Anti-Bacterial Agents; Ciprofloxacin; Culture Media; Drug Resistance, Bacterial; Isotope Labeling; Isotopes; Mass Spectrometry; Meropenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Thienamycins; Time Factors; Tobramycin	2014
Treatment failure due to induction of ciprofloxacin resistance during combination therapy with colistin and ciprofloxacin in multidrug-resistant Pseudomonas aeruginosa bacteraemia. International journal of antimicrobial agents, 2014, Volume: 43, Issue:4 Topics: Adult; Anti-Bacterial Agents; Bacteremia; Cefepime; Cephalosporins; Ciprofloxacin; Colistin; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Female; Humans; Immunocompromised Host; Meropenem; Pseudomonas aeruginosa; Pseudomonas Infections; Thienamycins; Tobramycin; Treatment Failure	2014
In vitro efficacy of antibiotic beads in treating abdominal vascular graft infections. Journal of vascular surgery, 2015, Volume: 62, Issue:4 Topics: Anti-Bacterial Agents; Aorta, Abdominal; Blood Vessel Prosthesis; Daptomycin; In Vitro Techniques; Meropenem; Polymethyl Methacrylate; Surgical Wound Infection; Thienamycins; Tobramycin	2015
Activities of antibiotic combinations against resistant strains of Pseudomonas aeruginosa in a model of infected THP-1 monocytes. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:1 Topics: Anti-Bacterial Agents; Cell Line; Ciprofloxacin; Colistin; Drug Resistance, Bacterial; Drug Synergism; Drug Therapy, Combination; Humans; Meropenem; Microbial Sensitivity Tests; Monocytes; Pseudomonas aeruginosa; Pseudomonas Infections; Thienamycins; Tobramycin	2015
Silver- and fluoride-containing mesoporous bioactive glasses versus commonly used antibiotics: Activity against multidrug-resistant bacterial strains isolated from patients with burns. Burns : journal of the International Society for Burn Injuries, 2016, Volume: 42, Issue:1 Topics: Amikacin; Animals; Anti-Bacterial Agents; Aztreonam; Burns; Carbenicillin; Cefepime; Ceftazidime; Ceftriaxone; Cell Survival; Cephalosporins; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Fluorides; Gentamicins; Glass; Humans; Imipenem; Meropenem; Mice; Microbial Sensitivity Tests; NIH 3T3 Cells; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Silver; Thienamycins; Tobramycin; Wound Infection	2016
Dynamics of Mutations during Development of Resistance by Pseudomonas aeruginosa against Five Antibiotics. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:7 Topics: Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Ceftazidime; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Microbial; Meropenem; Microbial Sensitivity Tests; Mutation; Piperacillin; Pseudomonas aeruginosa; Thienamycins; Tobramycin	2016
An Immunocompromised Child with Bloodstream Infection Caused by Two Escherichia coli Strains, One Harboring NDM-5 and the Other Harboring OXA-48-Like Carbapenemase. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:6 Topics: Adolescent; Amikacin; Anti-Bacterial Agents; Aztreonam; Bacterial Proteins; beta-Lactamases; beta-Lactams; Ciprofloxacin; Ertapenem; Escherichia coli; Female; Gentamicins; Humans; Immunocompromised Host; Meropenem; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tazobactam; Thienamycins; Tobramycin	2016
The Role of Reactive Oxygen Species in Antibiotic-Induced Cell Death in Burkholderia cepacia Complex Bacteria. PloS one, 2016, Volume: 11, Issue:7 Topics: Anti-Bacterial Agents; Biofilms; Burkholderia cepacia complex; Burkholderia Infections; Cell Death; Ciprofloxacin; Gene Expression Regulation, Bacterial; Meropenem; Microbial Sensitivity Tests; Reactive Oxygen Species; Repressor Proteins; Thienamycins; Tobramycin	2016
Novel glycopolymer sensitizes Burkholderia cepacia complex isolates from cystic fibrosis patients to tobramycin and meropenem. PloS one, 2017, Volume: 12, Issue:6 Topics: Acetylglucosamine; Anti-Bacterial Agents; Burkholderia cepacia complex; Cystic Fibrosis; Drug Resistance, Bacterial; Humans; Meropenem; Microbial Sensitivity Tests; Thienamycins; Tobramycin	2017
Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:12 Topics: Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Ciprofloxacin; Drug Combinations; Drug Resistance, Multiple, Bacterial; Febrile Neutropenia; Humans; Iatrogenic Disease; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pneumonia; Practice Guidelines as Topic; Pseudomonas aeruginosa; Pseudomonas Infections; Sepsis; Tazobactam; Thienamycins; Tobramycin	2017
Pharmacological Inhibition of the Pseudomonas aeruginosa MvfR Quorum-Sensing System Interferes with Biofilm Formation and Potentiates Antibiotic-Mediated Biofilm Disruption. Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:12 Topics: Anti-Bacterial Agents; Bacterial Proteins; Benzamides; Benzimidazoles; Biofilms; Colony Count, Microbial; Culture Media; Drug Synergism; Drug Tolerance; Gene Expression Regulation, Bacterial; Meropenem; Pseudomonas aeruginosa; Quorum Sensing; Thienamycins; Tobramycin; Transcription, Genetic	2017
Spatiotemporal pharmacodynamics of meropenem- and tobramycin-treated Pseudomonas aeruginosa biofilms. The Journal of antimicrobial chemotherapy, 2017, Dec-01, Volume: 72, Issue:12 Topics: Anti-Bacterial Agents; Biofilms; Biomass; Drug Tolerance; Green Fluorescent Proteins; Meropenem; Microbial Sensitivity Tests; Microbial Viability; Microscopy, Confocal; Pseudomonas aeruginosa; Spatio-Temporal Analysis; Staining and Labeling; Thienamycins; Tobramycin	2017
Levels of persisters influenced by aeration in Acinetobacter calcoaceticus-baumannii. Future microbiology, 2018, Volume: 13 Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Humans; Meropenem; Microbial Sensitivity Tests; Microbial Viability; Oxygen; Thienamycins; Tobramycin	2018
Where should antibiotic gradient diffusion strips be crossed to assess synergy? A comparison of the standard method with a novel method using steady-state antimicrobial concentrations. International journal of antimicrobial agents, 2019, Volume: 53, Issue:5 Topics: Anti-Bacterial Agents; Drug Synergism; Humans; Meropenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2019
Prevalence of in vitro synergistic antibiotic interaction between fosfomycin and nonsusceptible antimicrobials in carbapenem-resistant Pseudomonas aeruginosa. Journal of medical microbiology, 2019, Volume: 68, Issue:6 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Azabicyclo Compounds; Carbapenems; Ceftazidime; Cephalosporins; Drug Combinations; Drug Resistance, Bacterial; Drug Synergism; Fosfomycin; Humans; Meropenem; Prevalence; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam; Tobramycin; United States	2019
Combining antibiotics with antivirulence compounds can have synergistic effects and reverse selection for antibiotic resistance in Pseudomonas aeruginosa. PLoS biology, 2020, Volume: 18, Issue:8 Topics: Anti-Bacterial Agents; Bacterial Proteins; Ciprofloxacin; Colistin; Drug Combinations; Drug Resistance, Multiple, Bacterial; Drug Synergism; Furans; Gallium; Humans; Meropenem; Microbial Sensitivity Tests; Protein Biosynthesis; Pseudomonas aeruginosa; Quorum Sensing; Tobramycin; Virulence	2020
Thermal Stability and in Vitro Elution Kinetics of Alternative Antibiotics in Polymethylmethacrylate (PMMA) Bone Cement. The Journal of bone and joint surgery. American volume, 2021, 09-15, Volume: 103, Issue:18 Topics: Acinetobacter baumannii; Amikacin; Anti-Bacterial Agents; Bone Cements; Drug Stability; Fosfomycin; Kinetics; Meropenem; Microbial Sensitivity Tests; Polymethyl Methacrylate; Prosthesis-Related Infections; Staphylococcus aureus; Tobramycin	2021
Insights into collateral susceptibility and collateral resistance in Acinetobacter baumannii during antimicrobial adaptation. Letters in applied microbiology, 2021, Volume: 73, Issue:2 Topics: Acinetobacter baumannii; Acinetobacter Infections; Adaptation, Biological; Anti-Bacterial Agents; beta-Lactamases; Ciprofloxacin; Drug Collateral Sensitivity; Drug Resistance, Multiple, Bacterial; Humans; Meropenem; Microbial Sensitivity Tests; Polymyxin B; Tetracycline; Tobramycin	2021
Identifying alternative antibiotics that elute from calcium sulfate beads for treatment of orthopedic infections. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2022, Volume: 40, Issue:5 Topics: Amikacin; Anti-Bacterial Agents; Calcium Sulfate; Cefazolin; Meropenem; Minocycline; Tobramycin; Vancomycin	2022
Pharmacodynamics of Meropenem and Tobramycin for Neonatal Meningoencephalitis: Novel Approaches to Facilitate the Development of New Agents to Address the Challenge of Antimicrobial Resistance. Antimicrobial agents and chemotherapy, 2022, 04-19, Volume: 66, Issue:4 Topics: Animals; Anti-Bacterial Agents; Drug Resistance, Bacterial; Meningoencephalitis; Meropenem; Microbial Sensitivity Tests; Neonatal Sepsis; Pseudomonas aeruginosa; Rabbits; Tobramycin	2022
Introducing the Escalation Antibiogram: A Simple Tool to Inform Changes in Empiric Antimicrobials in the Nonresponding Patient. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2022, 11-14, Volume: 75, Issue:10 Topics: Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Bacteremia; Ceftriaxone; Ciprofloxacin; Ertapenem; Gentamicins; Gram-Negative Bacteria; Humans; Meropenem; Microbial Sensitivity Tests; Piperacillin, Tazobactam Drug Combination; Tobramycin; Trimethoprim, Sulfamethoxazole Drug Combination	2022
Antimicrobial resistance, virulence factors, and genotypes of Pseudomonas aeruginosa clinical isolates from Gorgan, northern Iran. International microbiology : the official journal of the Spanish Society for Microbiology, 2022, Volume: 25, Issue:4 Topics: Amikacin; Anti-Bacterial Agents; Ceftazidime; Ciprofloxacin; Colistin; Deoxyribonucleases; Drug Resistance, Bacterial; Genotype; Gentamicins; Humans; Imipenem; Iran; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Pancreatic Elastase; Phospholipases; Piperacillin; Piperacillin, Tazobactam Drug Combination; Polymyxin B; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Virulence Factors	2022
In Vitro Activity of Plazomicin Against Carbapenem Resistant Klebsiella pneumoniae Strains. Clinical laboratory, 2022, Jun-01, Volume: 68, Issue:6 Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Carbapenem-Resistant Enterobacteriaceae; Gentamicins; Humans; Klebsiella pneumoniae; Meropenem; Microbial Sensitivity Tests; Sisomicin; Tobramycin	2022
Time kill-assays of antibiotic combinations for multidrug resistant clinical isolates of OXA-48 carbapenemase producing Klebsiella pneumoniae. Acta microbiologica et immunologica Hungarica, 2022, Sep-16, Volume: 69, Issue:3 Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Ciprofloxacin; Colistin; Drug Synergism; Humans; Klebsiella Infections; Klebsiella pneumoniae; Meropenem; Microbial Sensitivity Tests; Tobramycin	2022
In vitro models to detect in vivo bile acid changes induced by antibiotics. Archives of toxicology, 2022, Volume: 96, Issue:12 Topics: Animals; Anti-Bacterial Agents; Bile Acids and Salts; Caco-2 Cells; Colistin; Doripenem; Humans; Meropenem; Rats; RNA, Ribosomal, 16S; Taurocholic Acid; Tobramycin	2022
Meropenem-loaded Cement Is Effective in Preventing Gram-negative Osteomyelitis in an Animal Model. Clinical orthopaedics and related research, 2023, 01-01, Volume: 481, Issue:1 Topics: Animals; Anti-Bacterial Agents; Aztreonam; Bone Cements; Ceftazidime; Ciprofloxacin; Escherichia coli; Male; Meropenem; Microbial Sensitivity Tests; Models, Animal; Osteomyelitis; Piperacillin; Rats; Tobramycin	2023
Genotypic resistance determined by whole genome sequencing versus phenotypic resistance in 234 Escherichia coli isolates. Scientific reports, 2023, 01-09, Volume: 13, Issue:1 Topics: Amikacin; Amoxicillin; Anti-Bacterial Agents; Cefepime; Cefotaxime; Ceftazidime; Ciprofloxacin; Clavulanic Acid; Escherichia coli; Escherichia coli Infections; Genotype; Gentamicins; Humans; Meropenem; Microbial Sensitivity Tests; Phenotype; Piperacillin; Retrospective Studies; Tazobactam; Tobramycin; Whole Genome Sequencing	2023