Page last updated: 2024-08-23

tobramycin and levofloxacin

tobramycin has been researched along with levofloxacin in 67 studies

Research

Studies (67)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (1.49)	18.2507
2000's	24 (35.82)	29.6817
2010's	34 (50.75)	24.3611
2020's	8 (11.94)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bonomo, RA; Endimiani, A; Hujer, AM; Hujer, KM; Luzzaro, F; Mantengoli, E; Migliavacca, R; Pagani, L; Rossolini, GM; Toniolo, A	1
Courvalin, P; Galimand, M; Périchon, B	1
Castanheira, M; Jones, RN; Mendes, RE; Sader, HS; Toleman, MA; Walsh, TR	1
Liu, Y; Shi, W; Wang, M; Wu, S; Xu, X; Ye, X; Zhang, Y	1
Andres, P; Centrón, D; Galas, M; Guerriero, L; Petroni, A; Quiroga, C; Quiroga, MP; Soler Bistué, AJ; Tokumoto, M; Tolmasky, ME; Vargas, LJ; Zorreguieta, A	1
Arakawa, Y; Suzuki, S; Wachino, J; Yamane, K	1
Bethel, CR; Bonomo, RA; Carias, LL; Endimiani, A; Fox, WR; Hall, GS; Hujer, AM; Hujer, KM; Hutton, RA; Jacobs, MR; Jenkins, SG; Paterson, DL; Perez, F; Rice, LB; Tenover, FC	1
Lombardo, F; Obach, RS; Waters, NJ	1
Bratu, S; Georgescu, C; Landman, D; Martin, DA; Quale, J	1
Cattoir, V; Nordmann, P; Poirel, L	1
Esteban, J; Fernández-Martínez, AI; Fernández-Roblas, R; Gadea, I; García-Almeida, D; Martín-de-Hijas, NZ	1
Bennett, JW; Herrera, ML; Jorgensen, JH; Lewis, JS; Wickes, BW	1
Baptista, BC; Correia, JD; da Fonseca, JD; Martínez-Martínez, L; Pomba, C	1
Bradford, PA; Jones, CH; Keeney, D; Ruzin, A; Tuckman, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Brunner, LS; Haas, W; Lee, JC; Morris, TW; Pillar, CM; Zurenko, GE	1
Dudley, MN; Griffith, DC; Miller, CE; Nolan, TG; Sabet, M; Senekeo-Effenberger, K	1
Burns, JL; Dudley, MN; Griffith, DC; King, P; Lomovskaya, O	1
Albertí, S; Bengoechea, JA; Doménech-Sánchez, A; Llobet, E; Martínez-Martínez, L; Padilla, E	1
Bulik, CC; Christensen, H; Nicolau, DP	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Dunman, PM; Hood, MI; Jacobs, AC; Sayood, K; Skaar, EP	1
Chang, SC; Chen, YC; Hsia, KC; Li, SY; Liao, MH; Lin, YC; Sheng, WH	1
Barber, M; Eberly, LE; Feeney, LA; Miller, GH; Summers, A; Wortmann, G; Zapor, MJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Clark, M; Doolittle, J; Giddings, MC; Khatun, J; Ramkissoon, K; Secrest, A; Su, HC; Wolfgang, MC	1
Glen, RC; Lowe, R; Mitchell, JB	1
Ekins, S; Williams, AJ; Xu, JJ	1
Hamprecht, A; Higgins, PG; Schneiders, T; Seifert, H	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Brozovic, A; Dowson, CG; Gazvoda, M; Košmrlj, J; Lloyd, A; Osmak, M; Proud, C; Roper, DI; Vajs, J	1
Ashenden, S; Bender, A; Cokol, M; Karakoc, I; Kuru, N; Mason, DJ; Meral, S; Stott, I; Weinstein, ZB	1
Bera, S; Mondal, D	1
Camp, JE; Nyamini, SB; Scott, FJ	1
Lohan, S; Mohammed, EHM; Parang, K; Tiwari, RK	1
Flynn, CM; Johnson, DM; Jones, RN	1
Burgess, DS; Hall, RG	1
Adam, HJ; Laing, N; Mayer, M; Zhanel, GG	1
Kim, EC; Kim, MS	2
Otuk, G; Ozbek, B	1
Dai, YH; Huang, YS; Lan, J; Sun, SY; Xie, LX	1
Gordon, YJ; Kowalski, RP; Mah, FS; Romanowski, EG; Shanks, RM	1
Cox, JC; Drachman, DA; Hibbard, ML; Kopelman, TR; Maly, TJ; Matthews, MR; O'Neill, PJ; Quan, AN; Vail, SJ	1
Dudley, MN; Griffith, DC; Lomovskaya, O; Sabet, M; Tarazi, Z; Tsivkovskii, R	1
Bai, N; Cai, Y; Kan, Q; Liang, B; Nie, X; Wang, R; Yang, J	1
Chen, ZJ; Han, L; Sun, ST; Wang, LY; Yue, J; Zhang, YQ	1
Blanco, AR; Papa, V; Spoto, CG; Sudano Roccaro, A	1
Ohashi, Y; Suzuki, T	1
Huang, H; Li, G; Lin, S	1
Fiel, SB	1
Mataraci-Kara, E; Ozbek Celik, B; Yilmaz, M	1
Aaron, SD; Bell, SC; Conrad, D; Dudley, MN; Fischer, R; Flume, PA; Geller, DE; Kerem, E; Loutit, JS; Morgan, EE; Smyth, AR; Stuart Elborn, J; VanDevanter, DR	1
Accorinti, M; Cecere, M; Colao, L; Gilardi, M; Pesci, FR; Salotti, A	1
Beaudoin, T; LiPuma, JJ; Tom, SK; Waters, V; Yau, YC	1
Cohen, F; Elborn, JS; Flume, PA; Loutit, J; VanDevanter, DR	1
Cheng, Z; Wu, G; Wu, W; Ye, C; Zheng, Q	1
Al-Hasan, MN; Ereshefsky, BJ; Gokun, Y; Martin, CA	1
Alfonso, EC; Gibbons, A; Miller, D; OʼBrien, TP; Palioura, S; Spierer, O	1
Istanbullu Tosun, A; Mataraci Kara, E; Özbek Çelik, B; Yilmaz, M	1
Bhamare, P; Dunman, PM; Johnson, W; Kinn, B; Laskey, E; Mei, JA; Nolin, L; Stalker, C; Wozniak, RAF	1
Ardebili, A; Bagheri, H; Goharrizi, MASB; Hjimohammadi, A; Izanloo, A; Jamali, A; Shahri, FN	1
Khan, M; Ma, K; Wan, I; Willcox, MD	1
Belov, DF; Deng, QQ; Jiang, H; Li, JL; Li, SH; Li, WJ; Luo, XQ; Nikolaenko, VP; She, TT; Wang, PD; Wang, Y; Yang, ZW	1
Chen, M; Chen, R; Hu, Y; Huang, D; Jiang, A; Li, J; Li, S; Liang, X; Meng, Z; Shen, Y; Wumaier, A; Xie, L; Yu, X	1

Reviews

2 review(s) available for tobramycin and levofloxacin

Article	Year
Insights of synthetic analogues of anti-leprosy agents. Bioorganic & medicinal chemistry, 2019, 07-01, Volume: 27, Issue:13 Topics: Humans; Leprostatic Agents; Leprosy; Structure-Activity Relationship	2019
Aerosolized antibiotics in cystic fibrosis: an update. Expert review of respiratory medicine, 2014, Volume: 8, Issue:3 Topics: Administration, Inhalation; Amikacin; Anti-Bacterial Agents; Aztreonam; Colistin; Cystic Fibrosis; Equipment Design; Humans; Levofloxacin; Nebulizers and Vaporizers; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Tobramycin	2014

Trials

4 trial(s) available for tobramycin and levofloxacin

Article	Year
[Study of different methods in reducing conjunctival bacteria before cataract surgery]. Zhonghua yi xue za zhi, 2009, Sep-22, Volume: 89, Issue:35 Topics: Aged; Antibiotic Prophylaxis; Cataract; Cataract Extraction; Conjunctiva; Humans; Levofloxacin; Middle Aged; Ofloxacin; Tobramycin	2009
Comparative study of the disinfection effects of three types of conjunctiva sac irrigations. Eye science, 2013, Volume: 28, Issue:1 Topics: Aged; Anti-Infective Agents, Local; Cataract; Chlorhexidine; Conjunctiva; Disinfection; Drug Combinations; Ethanol; Gentamicins; Humans; Iodine; Lens Implantation, Intraocular; Levofloxacin; Ophthalmic Solutions; Phacoemulsification; Postoperative Care; Prospective Studies; Therapeutic Irrigation; Tobramycin	2013
A phase 3, open-label, randomized trial to evaluate the safety and efficacy of levofloxacin inhalation solution (APT-1026) versus tobramycin inhalation solution in stable cystic fibrosis patients. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2015, Volume: 14, Issue:4 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Chronic Disease; Cystic Fibrosis; Female; Forced Expiratory Volume; Humans; Levofloxacin; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Quality of Life; Tobramycin; Treatment Outcome; Young Adult	2015
Safety and efficacy of prolonged levofloxacin inhalation solution (APT-1026) treatment for cystic fibrosis and chronic Pseudomonas aeruginosa airway infection. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2016, Volume: 15, Issue:5 Topics: Administration, Inhalation; Adult; Aerosols; Anti-Bacterial Agents; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Monitoring; Female; Humans; Levofloxacin; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin; Treatment Outcome	2016

Other Studies

61 other study(ies) available for tobramycin and levofloxacin

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Spread in an Italian hospital of a clonal Acinetobacter baumannii strain producing the TEM-92 extended-spectrum beta-lactamase. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6 Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Cross Infection; Humans; Italy; Microbial Sensitivity Tests	2007
Transferable resistance to aminoglycosides by methylation of G1405 in 16S rRNA and to hydrophilic fluoroquinolones by QepA-mediated efflux in Escherichia coli. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7 Topics: Amino Acid Motifs; Amino Acid Sequence; Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; Conjugation, Genetic; Conserved Sequence; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Escherichia coli; Escherichia coli Proteins; Fluoroquinolones; Genes, rRNA; Methylation; Methyltransferases; Microbial Sensitivity Tests; Molecular Sequence Data; Norfloxacin; Plasmids; Sequence Analysis, DNA; Sequence Homology, Amino Acid	2007
Characterization of an integron carrying blaIMP-1 and a new aminoglycoside resistance gene, aac(6')-31, and its dissemination among genetically unrelated clinical isolates in a Brazilian hospital. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7 Topics: Acinetobacter; Amino Acid Sequence; Aminoglycosides; Anti-Bacterial Agents; Base Sequence; Brazil; Codon, Terminator; Cross Infection; Drug Resistance, Multiple, Bacterial; Gene Transfer, Horizontal; Genes, Bacterial; Hospitals; Humans; Integrons; Microbial Sensitivity Tests; Molecular Sequence Data; Open Reading Frames; Plasmids; Pseudomonas putida; Transcription, Genetic	2007
Prevalence and expression of the plasmid-mediated quinolone resistance determinant qnrA1. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11 Topics: Anti-Infective Agents; Base Sequence; Ciprofloxacin; DNA, Bacterial; Drug Resistance, Bacterial; Enterobacter cloacae; Enterobacteriaceae; Gene Expression Regulation, Bacterial; Genes, Bacterial; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Polymerase Chain Reaction; Promoter Regions, Genetic; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid	2007
Complex class 1 integrons with diverse variable regions, including aac(6')-Ib-cr, and a novel allele, qnrB10, associated with ISCR1 in clinical enterobacterial isolates from Argentina. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12 Topics: Alleles; Amino Acid Sequence; Argentina; Bacterial Proteins; Base Sequence; beta-Lactamases; Cross Infection; DNA Transposable Elements; Drug Resistance, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Integrons; Microbial Sensitivity Tests; Molecular Sequence Data; Polymerase Chain Reaction; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid	2007
Plasmid-mediated qepA gene among Escherichia coli clinical isolates from Japan. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:4 Topics: Anti-Bacterial Agents; Conjugation, Genetic; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Fluoroquinolones; Hospitals; Humans; Japan; Microbial Sensitivity Tests; Plasmids; Prevalence	2008
Presence of plasmid-mediated quinolone resistance in Klebsiella pneumoniae isolates possessing blaKPC in the United States. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:7 Topics: Aged; Bacterial Proteins; Base Sequence; beta-Lactamases; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Genes, Bacterial; Humans; Klebsiella Infections; Klebsiella pneumoniae; Male; Microbial Sensitivity Tests; Molecular Epidemiology; Plasmids; Quinolones; United States	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:9 Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; beta-Lactamases; Drug Resistance, Bacterial; Endemic Diseases; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; New York City; Sequence Analysis, DNA	2008
Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:10 Topics: Aged; Base Sequence; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Female; Fluoroquinolones; France; Genes, Bacterial; Humans; Models, Genetic; Molecular Sequence Data; Plasmids	2008
In vitro activities of tigecycline and 10 other antimicrobials against nonpigmented rapidly growing mycobacteria. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:11 Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Minocycline; Mycobacterium; Mycobacterium Infections; Pigmentation; Species Specificity; Tigecycline	2008
KPC-2-producing Enterobacter cloacae and pseudomonas putida coinfection in a liver transplant recipient. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:1 Topics: Anti-Bacterial Agents; beta-Lactamases; Enterobacter cloacae; Female; Humans; Liver Transplantation; Microbial Sensitivity Tests; Middle Aged; Pseudomonas putida; RNA, Ribosomal, 16S	2009
Detection of the pandemic O25-ST131 human virulent Escherichia coli CTX-M-15-producing clone harboring the qnrB2 and aac(6')-Ib-cr genes in a dog. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:1 Topics: Animals; Anti-Bacterial Agents; Dogs; Drug Resistance, Bacterial; Escherichia coli; Genes, Bacterial; Humans; Plasmids; Virulence	2009
Characterization and sequence analysis of extended-spectrum-{beta}-lactamase-encoding genes from Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis isolates collected during tigecycline phase 3 clinical trials. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:2 Topics: Anti-Bacterial Agents; Bacterial Infections; beta-Lactamases; Clinical Trials, Phase III as Topic; DNA Primers; Drug Resistance, Bacterial; Escherichia coli; Humans; Isoelectric Focusing; Klebsiella pneumoniae; Microbial Sensitivity Tests; Minocycline; Proteus mirabilis; Reverse Transcriptase Polymerase Chain Reaction; Tigecycline	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Besifloxacin, a novel fluoroquinolone, has broad-spectrum in vitro activity against aerobic and anaerobic bacteria. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:8 Topics: Anti-Bacterial Agents; Azepines; Bacteria, Anaerobic; Drug Resistance, Bacterial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests	2009
Efficacy of aerosol MP-376, a levofloxacin inhalation solution, in models of mouse lung infection due to Pseudomonas aeruginosa. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:9 Topics: Administration, Inhalation; Aerosols; Animals; Anti-Bacterial Agents; Aztreonam; Disease Models, Animal; Female; Levofloxacin; Lung Diseases; Mice; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2009
In vitro pharmacodynamics of levofloxacin and other aerosolized antibiotics under multiple conditions relevant to chronic pulmonary infection in cystic fibrosis. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1 Topics: Aerosols; Anti-Bacterial Agents; Bacteria; Biofilms; Chronic Disease; Ciprofloxacin; Colony Count, Microbial; Cystic Fibrosis; Humans; Levofloxacin; Lung Diseases; Microbial Sensitivity Tests; Ofloxacin; Sputum	2010
Klebsiella pneumoniae AcrAB efflux pump contributes to antimicrobial resistance and virulence. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1 Topics: Animals; Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Culture Media; Defensins; DNA, Bacterial; Drug Resistance, Bacterial; Genotype; Humans; Klebsiella Infections; Klebsiella pneumoniae; Lipopolysaccharides; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Phenotype; Plasmids; Polymyxin B; Polysaccharides; Repressor Proteins; RNA, Bacterial	2010
In vitro potency of CXA-101, a novel cephalosporin, against Pseudomonas aeruginosa displaying various resistance phenotypes, including multidrug resistance. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1 Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Cephalosporins; Child; Child, Preschool; Cross Infection; Drug Combinations; Drug Resistance, Multiple, Bacterial; Humans; Infant; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Pseudomonas aeruginosa; Tazobactam; Young Adult	2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Acinetobacter baumannii increases tolerance to antibiotics in response to monovalent cations. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:3 Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Proteins; Cations, Monovalent; Culture Media; Drug Resistance, Bacterial; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Humans; Microbial Sensitivity Tests; Oligonucleotide Array Sequence Analysis; Proteomics; Sodium Chloride; Virulence Factors	2010
Genetic basis of multidrug resistance in Acinetobacter clinical isolates in Taiwan. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5 Topics: Acinetobacter baumannii; Acinetobacter Infections; Aminoglycosides; beta-Lactamases; Carbapenems; Cephalosporins; DNA Gyrase; Drug Resistance, Bacterial; Drug Resistance, Multiple; Fluoroquinolones; Humans; Taiwan	2010
In vitro activity of the aminoglycoside antibiotic arbekacin against Acinetobacter baumannii-calcoaceticus isolated from war-wounded patients at Walter Reed Army Medical Center. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:7 Topics: Acinetobacter baumannii; Aminoglycosides; Anti-Bacterial Agents; Carbapenems; Dibekacin; Hospitals, Military; Humans; Microbial Sensitivity Tests; Warfare	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
The development of ciprofloxacin resistance in Pseudomonas aeruginosa involves multiple response stages and multiple proteins. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:11 Topics: Anti-Infective Agents; Bacterial Proteins; Ciprofloxacin; DNA, Bacterial; Drug Resistance, Bacterial; Electrophoresis, Gel, Two-Dimensional; Methylmalonate-Semialdehyde Dehydrogenase (Acylating); Microbial Sensitivity Tests; Pseudomonas aeruginosa; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Succinate-Semialdehyde Dehydrogenase	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:12 Topics: Acinetobacter baumannii; Acinetobacter Infections; Bacterial Proteins; Carbapenems; Drug Resistance, Bacterial; Fatal Outcome; Humans; Male; Middle Aged; Molecular Sequence Data; Mutation, Missense; Reverse Transcriptase Polymerase Chain Reaction	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Diaryltriazenes as antibacterial agents against methicillin resistant Staphylococcus aureus (MRSA) and Mycobacterium smegmatis. European journal of medicinal chemistry, 2017, Feb-15, Volume: 127 Topics: Anti-Bacterial Agents; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Mycobacterium smegmatis; Triazenes	2017
Prediction of Antibiotic Interactions Using Descriptors Derived from Molecular Structure. Journal of medicinal chemistry, 2017, 05-11, Volume: 60, Issue:9 Topics: Anti-Bacterial Agents; Drug Interactions; Molecular Structure	2017
Cyrene™ is a green alternative to DMSO as a solvent for antibacterial drug discovery against ESKAPE pathogens. RSC medicinal chemistry, 2020, Jan-01, Volume: 11, Issue:1 Topics:	2020
Amphiphilic cyclic peptide [W European journal of medicinal chemistry, 2022, May-05, Volume: 235 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Gram-Negative Bacteria; Gram-Positive Bacteria; Meropenem; Microbial Sensitivity Tests; Peptides, Cyclic; Pseudomonas aeruginosa	2022
In vitro efficacy of levofloxacin alone or in combination tested against multi-resistant Pseudomonas aeruginosa strains. Journal of chemotherapy (Florence, Italy), 1996, Volume: 8, Issue:6 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aztreonam; Ceftazidime; Ciprofloxacin; Drug Resistance, Multiple; Gentamicins; Humans; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Piperacillin; Pseudomonas aeruginosa; Tobramycin	1996
In vitro activity of parenteral Beta-lactams, levofloxacin and tobramycin alone or in combination against extended-spectrum Beta-lactamase producing Klebsiella pneumoniae. International journal of antimicrobial agents, 2004, Volume: 24, Issue:1 Topics: beta-Lactamases; beta-Lactams; Drug Therapy, Combination; Infusions, Parenteral; Klebsiella pneumoniae; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Tobramycin	2004
Mutant prevention concentrations of levofloxacin alone and in combination with azithromycin, ceftazidime, colistin (Polymyxin E), meropenem, piperacillin-tazobactam, and tobramycin against Pseudomonas aeruginosa. Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:6 Topics: Anti-Bacterial Agents; Azithromycin; Ceftazidime; Colistin; Dose-Response Relationship, Drug; Drug Synergism; In Vitro Techniques; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Mutation; Ofloxacin; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Thienamycins; Tobramycin	2006
Bilateral acanthamoeba keratitis after orthokeratology. Cornea, 2009, Volume: 28, Issue:3 Topics: Acanthamoeba Keratitis; Biguanides; Contact Lenses, Extended-Wear; Drug Therapy, Combination; Female; Functional Laterality; Humans; Levofloxacin; Ofloxacin; Orthokeratologic Procedures; Tobramycin; Visual Acuity; Young Adult	2009
Bilateral acanthamoeba keratitis after orthokeratology. Cornea, 2010, Volume: 29, Issue:6 Topics: Acanthamoeba Keratitis; Antiprotozoal Agents; Biguanides; Drug Therapy, Combination; Escherichia coli Infections; Female; Functional Laterality; Humans; Levofloxacin; Microscopy, Phase-Contrast; Ofloxacin; Orthokeratologic Procedures; Tobramycin; Visual Acuity; Young Adult	2010
Post-antibiotic effect of levofloxacin and tobramycin alone or in combination with cefepime against Pseudomonas aeruginosa. Chemotherapy, 2009, Volume: 55, Issue:6 Topics: Anti-Bacterial Agents; Bacteremia; Cefepime; Cephalosporins; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Time Factors; Tobramycin	2009
Topical levofloxacin 1.5% overcomes in vitro resistance in rabbit keratitis models. Acta ophthalmologica, 2010, Volume: 88, Issue:4 Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Cefazolin; Ciprofloxacin; Colony Count, Microbial; Corneal Stroma; Corneal Ulcer; Disease Models, Animal; Drug Resistance, Bacterial; Eye Infections, Bacterial; Levofloxacin; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Tobramycin; Vancomycin	2010
Empiric, broad-spectrum antibiotic therapy with an aggressive de-escalation strategy does not induce gram-negative pathogen resistance in ventilator-associated pneumonia. Surgical infections, 2010, Volume: 11, Issue:5 Topics: Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Resistance, Bacterial; Gram-Negative Bacteria; Humans; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumonia, Ventilator-Associated; Retrospective Studies; Tobramycin	2010
Levofloxacin reduces inflammatory cytokine levels in human bronchial epithelia cells: implications for aerosol MP-376 (levofloxacin solution for inhalation) treatment of chronic pulmonary infections. FEMS immunology and medical microbiology, 2011, Volume: 61, Issue:2 Topics: Administration, Inhalation; Aerosols; Anti-Inflammatory Agents; Cell Line; Chronic Disease; Epithelial Cells; Gene Expression Profiling; Humans; Interleukin-6; Interleukin-8; Levofloxacin; Ofloxacin; Pneumonia; Tobramycin	2011
Mutant prevention concentration of colistin alone and in combination with levofloxacin or tobramycin against multidrug-resistant Acinetobacter baumannii. International journal of antimicrobial agents, 2012, Volume: 40, Issue:5 Topics: Acinetobacter baumannii; Colistin; Drug Interactions; Drug Resistance, Multiple, Bacterial; Humans; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin; Selection, Genetic; Tobramycin	2012
[The changes of ocular bacterial isolates and in vitro antimicrobial susceptibility in the past six years]. [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2012, Volume: 48, Issue:6 Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Eye; Eye Infections, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Retrospective Studies; Staphylococcus epidermidis; Tobramycin	2012
Susceptibility of methicillin-resistant Staphylococci clinical isolates to netilmicin and other antibiotics commonly used in ophthalmic therapy. Current eye research, 2013, Volume: 38, Issue:8 Topics: Anti-Bacterial Agents; Aza Compounds; Azithromycin; Chloramphenicol; Drug Resistance; Eye Infections, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Moxifloxacin; Netilmicin; Quinolines; Staphylococcus epidermidis; Tobramycin; Vancomycin	2013
Combination effect of antibiotics against bacteria isolated from keratitis using fractional inhibitory concentration index. Cornea, 2013, Volume: 32, Issue:7 Topics: Anti-Bacterial Agents; Aza Compounds; Bacteria; Cefmenoxime; Corneal Ulcer; Drug Combinations; Drug Synergism; Eye Infections, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Pseudomonas; Quinolines; Staphylococcus; Streptococcus; Tobramycin	2013
Effects of various antibiotics alone or in combination with doripenem against Klebsiella pneumoniae strains isolated in an intensive care unit. BioMed research international, 2014, Volume: 2014 Topics: Carbapenems; Colistin; Doripenem; Dose-Response Relationship, Drug; Drug Combinations; Humans; Intensive Care Units; Klebsiella Infections; Klebsiella pneumoniae; Levofloxacin; Minocycline; Rifampin; Tigecycline; Tobramycin	2014
Levofloxacin and Tobramycin for Severe Bacterial Keratouveitis. Ocular immunology and inflammation, 2016, Volume: 24, Issue:5 Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteria; Contact Lenses; Corneal Ulcer; Drug Therapy, Combination; Female; Humans; Levofloxacin; Male; Middle Aged; Ophthalmic Solutions; Risk Factors; Tobramycin; Uveitis, Anterior; Visual Acuity; Young Adult	2016
Effect of High-Dose Antimicrobials on Biofilm Growth of Achromobacter Species Isolated from Cystic Fibrosis Patients. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:1 Topics: Achromobacter; Amikacin; Anti-Bacterial Agents; Aztreonam; Biofilms; Colistin; Cystic Fibrosis; Gram-Negative Bacterial Infections; Humans; Levofloxacin; Microbial Sensitivity Tests; Plankton; Tobramycin	2016
A therapeutic delivery system for chronic osteomyelitis via a multi-drug implant based on three-dimensional printing technology. Journal of biomaterials applications, 2016, Volume: 31, Issue:2 Topics: Animals; Drug Delivery Systems; Drug Implants; Drug Liberation; Levofloxacin; Male; Osteomyelitis; Polyesters; Printing, Three-Dimensional; Rabbits; Tobramycin	2016
Comparison of ß-lactam plus aminoglycoside versus ß-lactam plus fluoroquinolone empirical therapy in serious nosocomial infections due to Gram-negative bacilli. Journal of chemotherapy (Florence, Italy), 2017, Volume: 29, Issue:1 Topics: Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Cohort Studies; Critical Illness; Cross Infection; Drug Therapy, Combination; Female; Fluoroquinolones; Gentamicins; Gram-Negative Bacterial Infections; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Proportional Hazards Models; Retrospective Studies; Tobramycin; Treatment Outcome	2017
Clinical Features, Antibiotic Susceptibility Profile, and Outcomes of Infectious Keratitis Caused by Stenotrophomonas maltophilia. Cornea, 2018, Volume: 37, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amikacin; Anti-Bacterial Agents; Ciprofloxacin; Corneal Ulcer; Eye Infections, Bacterial; Female; Gram-Negative Bacterial Infections; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Polymyxin B; Retrospective Studies; Risk Factors; Stenotrophomonas maltophilia; Tobramycin; Trimethoprim, Sulfamethoxazole Drug Combination; Young Adult	2018
Evaluation of the synergy of ceftazidime/avibactam in combination with colistin, doripenem, levofloxacin, tigecycline, and tobramycin against OXA-48 producing Enterobacterales. Journal of chemotherapy (Florence, Italy), 2020, Volume: 32, Issue:4 Topics: Anti-Bacterial Agents; Azabicyclo Compounds; beta-Lactamases; Carbapenem-Resistant Enterobacteriaceae; Ceftazidime; Colistin; Doripenem; Drug Combinations; Drug Synergism; Enterobacter cloacae; Enterobacteriaceae; Escherichia coli; Humans; Klebsiella pneumoniae; Levofloxacin; Microbial Sensitivity Tests; Real-Time Polymerase Chain Reaction; Tigecycline; Tobramycin	2020
Antimicrobial Activity of a Triple Antibiotic Combination Toward Ocular Pseudomonas aeruginosa Clinical Isolates. Translational vision science & technology, 2022, 05-02, Volume: 11, Issue:5 Topics: Anti-Bacterial Agents; Bacitracin; Drug Combinations; Erythromycin; Framycetin; Humans; Keratitis; Levofloxacin; Moxifloxacin; Polymyxin B; Pseudomonas aeruginosa; Pseudomonas Infections; Rifampin; Tobramycin; Trimethoprim	2022
Antimicrobial resistance, virulence factors, and genotypes of Pseudomonas aeruginosa clinical isolates from Gorgan, northern Iran. International microbiology : the official journal of the Spanish Society for Microbiology, 2022, Volume: 25, Issue:4 Topics: Amikacin; Anti-Bacterial Agents; Ceftazidime; Ciprofloxacin; Colistin; Deoxyribonucleases; Drug Resistance, Bacterial; Genotype; Gentamicins; Humans; Imipenem; Iran; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Pancreatic Elastase; Phospholipases; Piperacillin; Piperacillin, Tazobactam Drug Combination; Polymyxin B; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Virulence Factors	2022
Ciprofloxacin resistance and tolerance of Pseudomonas aeruginosa ocular isolates. Contact lens & anterior eye : the journal of the British Contact Lens Association, 2023, Volume: 46, Issue:3 Topics: Agar; Anti-Bacterial Agents; Ceftazidime; Ciprofloxacin; Gentamicins; Humans; Imipenem; Keratitis; Levofloxacin; Microbial Sensitivity Tests; Piperacillin; Polymyxin B; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2023
Vestnik oftalmologii, 2023, Volume: 139, Issue:2 Topics: Anti-Bacterial Agents; Bacillaceae; Cataract; Cataract Extraction; China; Dexamethasone; Endophthalmitis; Estuaries; Eye Infections, Bacterial; Genome, Bacterial; Geologic Sediments; Humans; Levofloxacin; Phylogeny; Postoperative Complications; Povidone-Iodine; Retrospective Studies; Tobramycin	2023
Microbial distributions in the conjunctiva and lacrimal sacs of patients with chronic dacryocystitis in a tertiary hospital. International ophthalmology, 2023, Volume: 43, Issue:9 Topics: Bacteria; Conjunctiva; Dacryocystitis; Dacryocystorhinostomy; Gram-Negative Bacteria; Humans; Levofloxacin; Nasolacrimal Duct; Tertiary Care Centers; Tobramycin	2023