Compounds > tobramycin
Page last updated: 2024-08-23

tobramycin and framycetin

tobramycin has been researched along with framycetin in 116 studies

Research

Studies (116)

TimeframeStudies, this research(%)All Research%
pre-199038 (32.76)18.7374
1990's15 (12.93)18.2507
2000's38 (32.76)29.6817
2010's23 (19.83)24.3611
2020's2 (1.72)2.80

Authors

AuthorsStudies
Alborn, WE; Allen, NE; Kirst, HA; Toth, JE1
Cedergren, R; Leclerc, F1
Huffman, GR; Tok, JB1
Cashman, DJ; Kellogg, GE; Rife, JP1
Des Jean, RC; Dunn, LJ; Tok, JB1
Fenker, J; Tok, JB1
Baboolal, N; Tok, JB; Wong, W1
Rando, RR; Ryu, DH2
Detering, C; Varani, G1
Hines, JV; Means, JA1
Avison, MB; Okazaki, A1
Baasov, T; Cherniavsky, M; Hainrichson, M; Nudelman, I; Shallom-Shezifi, D; Yaniv, O; Yaron, S1
Adams, J; de Oliveira Garcia, D; Doi, Y; Paterson, DL1
Arakawa, Y; Ike, Y; Kimura, K; Kurokawa, H; Shibata, N; Shibayama, K; Suzuki, S; Wachino, J; Yamane, K1
Kirikae, T; Kitao, T; Miyoshi-Akiyama, T1
Aboul-ela, F; Allam, K; Bodoor, K; Boisdore, M; Boyapati, V; Gopu, V; Miller, J; Treleaven, WD; Weldeghiorghis, T1
Aggen, JB; Armstrong, ES; Bonomo, RA; Choudhary, Y; Endimiani, A; Hujer, AM; Hujer, KM1
Baussanne, I; Bussière, A; Décout, JL; Ennifar, E; Ganem-Elbaz, C; Halder, S; Mingeot-Leclercq, MP; Ouberai, M; Paris, JM; Riou, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Brown, JM; Gonoi, T; Ishikawa, J; Kogure, T; Mikami, Y; Shimada, R; Yazawa, K1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Herdewijn, P; Maiti, M; Nauwelaerts, K1
Baussanne, I; Bussière, A; Décout, JL; Jolivalt, C; Mingeot-Leclercq, MP; Ouberai, M; Zimmermann, L1
Geng, H; Huang, J; Jiang, H; Kong, X; Li, L; Liu, J; Luo, C; Xie, Y; Ye, F; Yue, L; Zhou, R1
Barros R S, V; Das, I; Décout, JL; Désiré, J; El Khoury, M; Mingeot-Leclercq, MP; Sautrey, G; Zimmermann, L1
Briée, F; Décout, JL; Kempf, J; Mingeot-Leclercq, MP; Swain, J; Zimmermann, L1
Kondo, S; Takeuchi, T; Umezawa, H; Yagisawa, M1
Witchitz, JL1
Brown, DF; Porthouse, A; Rogers, T; Smith, RG1
DeFuria, MD; Price, KE; Pursiano, TA1
Brumfitt, W; Hamilton-Miller, JM; Reyonolds, AV1
Hybels, RL1
Bennett, WM; Gilbert, DN; Houghton, DC; Parker, RA; Plamp, CE; Porter, GA1
Förström, L; Pirilä, L; Pirilä, V1
Ball, AP; Gray, JA; Murdoch, JM1
Burkardt, HJ; Kleber, I; Pühler, A; Traub, WH1
de Rosayro, M; Healy, TE1
Moore, BJ; Ryden, R1
Bruns, WT; Davis, SD1
Garretson, HD; Noonan, JD; Reid, KH; Shields, CB1
Capmau, ML; Edery, M; Goffic, FL; Moreau, N1
Acar, JF; Goldstein, F; Le Goffic, F; Talbot, JN; Witchitz, JL1
Ridgway, HB; Schorr, WF1
Neu, HC1
Baca, B; Dublanchet, A; Duval, J; Le Goffic, F; Soussy, CJ1
Kondo, S; Umezawa, H1
Brown, EM; Butters, RR; Chen, CJ; Katz, CL1
Cannon, M; Davies, J; Moazed, D; Noller, HF; Woodcock, J1
Armstrong, FA; Cammack, R; George, SJ; Hatchikian, EC; Thomson, AJ1
Lightman, JM; Mannis, MJ; Pinilla, C; Serdahl, CL; Shapiro, DR; Zadnik, K1
Lerk, CF; Stoutenbeek, CP; van Saene, HK; van Saene, JJ1
Bonetti, A; Luthy, R; Siegenthaler, WE1
Schacht, J; Smith, DE; Williams, SE1
Farruggella, T; Josepovitz, C; Kaloyanides, GJ; Levine, R1
Umezawa, S1
Hori, R; Inui, K; Kohno, M; Saito, H; Yamamoto, K1
Booij, LH; Crul, JF; Rutten, CL; Rutten, JM1
Black, FO; Hawkins, JE; Johnsson, LG; Kingsley, TC; Matz, GJ1
Hedges, RW; Shannon, KP1
Gunter, JM; Gupta, VD; Stewart, KR1
Mulder, JG; van der Waaij, D; Welling, GW; Wiersma, WE1
Fujita, Y; Kitano, S; Mori, I1
Breeze, AS; Simpson, AM1
Powell, JH; Reidenberg, MM1
Hecht, DW; Parisi, JT1
Birdsey, TJ; Davidge, CG; Garland, HO; Harpur, ES; McLaughlin, JT; Oakes, LM; Smith, AJ1
Hamasaki, K; Killian, J; Rando, RR; Wang, Y1
Glossmann, H; Grabner, M; Grabner-Weiss, C; Hering, S; Pichler, M; Reimer, D; Striessnig, J; Wang, Z1
Demidchuk, IuA; Fedorenko, VA; Golets, LM1
Jensen, RJ1
Cho, J; Hamasaki, K; Killian, J; Rando, RR1
Chattin, SE; Mathew, AG; Upchurch, WG1
Hermann, T; Westhof, E2
Abu-Hasan, N; Adwan, K; Al-Asmar, H1
Hu, W; Jaishree, TJ; Jiang, L; Majumdar, A; Patel, DJ; Xu, W1
Michael, K; Tor, Y; Wang, H1
Bent, JP; Hebert, RL; King, GE; Vick, ML1
Czeizel, AE; Olsen, J; Rockenbauer, M; Sørensen, HT1
Martín, M; Mateu, E1
Bedwell, DM; Keeling, K; Manuvakhova, M1
Drainas, D; Stathopoulos, C; Tekos, A; Tsagla, A1
Church, CA; Jinn, TH; John, EO; Jung, TT; Kim, PD; Russell, PT1
Litovchick, A; Rando, RR; Ryu, DH1
Hu, XL; Li, N; Liu, SP1
Schippers, EF; van Dissel, JT1
Bischoff, KM; Callaway, TR; Edrington, TS; Genovese, KJ; Nisbet, DJ1
Arya, DP; Coffee, RL; Xue, L1
Fuhrhop, JH; Kopaczynska, M; Lauer, M; Schaefer, A; Schulz, A; Wang, T1
Amin, D; Bertin, D; Cockrum, PC; Kennedy, M; Notivol, R; Whitling, A1
Deb, JK; Jana, S1
García-Rubio, I; Martínez-Cócera, C; Robledo Echarren, T; Vázquez Cortés, S1
Buszman, E; Trzcionka, J; Wrześniok, D1
Jakoniuk, P; Leszczyńska, K; Sacha, PT; Wieczorek, P; Zalewska, M1
Hanko, VP; Liu, HH; Liu, X; Rohrer, JS; Tang, X; Zhang, S; Zheng, C1
Childs-Disney, JL; Disney, MD; Labuda, LP; Paul, DJ; Poplawski, SG; Pushechnikov, A; Tran, T; Velagapudi, SP; Wu, M1
Dediulescu, DF; Dediulescu, L1
de Keizer, RJ; Jager, MJ; van Zuuren, EJ; Wijnmaalen, AL1
Disney, MD; Tran, T1
Dix, AV; Esko, JD; Fischer, L; Redgate, CP; Sarrazin, S; Tor, Y1
Cowan, JA; Patwardhan, A1
Fenner, AM; Kerns, RJ1
Cuthbertson, BH; Daneman, N; Fowler, RA; Sarwar, S1
Dahal, RK; Kirikae, T; Mishra, SK; Miyoshi-Akiyama, T; Ohara, H; Pokhrel, BM; Shimada, K; Tada, T1
Ahmed, HM; Derayea, SM; Hammad, MA; Omar, MA1
Aly, AA; Hammad, MA; Nagy, DM; Omar, MA1
Benhida, R; Darfeuille, F; Di Giorgio, A; Duca, M; Staedel, C; Tran, TP; Vo, DD1
Kalinec, F; Kalinec, G; Park, C; Thein, P1
Chen, L; Jiang, N; Li, W; Lin, X; Wang, J; Xie, Z; You, L; Zhang, Q; Zhao, Q1
Böttger, EC; Crich, D; Hobbie, SN; Kato, T; Mandhapati, AR; Shcherbakov, D; Vasella, A; Yang, G1
Deng, R; Hu, X; Huang, J; Li, Q; Shi, Q; Sun, Y; Teng, M; Yang, Y; Zhang, G; Zhang, Z1
Čusak, A; Durán-Alonso, MB; Fernández-Martínez, M; Fujs, Š; García-Mateo, N; Ishikawa, M; Knipper, M; Kosec, G; López-Hernández, I; Löwenheim, H; Martínez-Martínez, L; Müller, M; Petković, H; Rüttiger, L; Schimmang, T; Singer, W1
Bhamare, P; Dunman, PM; Johnson, W; Kinn, B; Laskey, E; Mei, JA; Nolin, L; Stalker, C; Wozniak, RAF1
Hall, RM; Harmer, CJ; Lebreton, F; McGann, PT; Stam, J1

Reviews

4 review(s) available for tobramycin and framycetin

ArticleYear
Antibacterial Drugs today: II.
    Drugs, 1975, Volume: 10, Issue:2

    Topics: Aminoglycosides; Anti-Bacterial Agents; Cephalexin; Cephaloridine; Cephalosporins; Cephalothin; Cephamycins; Cephradine; Framycetin; Gentamicins; Humans; Kanamycin; Neomycin; Paromomycin; Polymyxins; Streptomycin; Tobramycin

1975
Aminoglycoside antibiotics in infectious diseases. An overview.
    The American journal of medicine, 1986, Jun-30, Volume: 80, Issue:6B

    Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Drug Resistance, Microbial; Drug Therapy, Combination; Endocarditis, Bacterial; Gentamicins; Humans; Kanamycin; Kinetics; Neomycin; Netilmicin; Pneumonia; Sepsis; Sisomicin; Streptomycin; Tobramycin

1986
Structures and syntheses of aminoglycoside antibiotics.
    Advances in carbohydrate chemistry and biochemistry, 1974, Volume: 30

    Topics: Aminoglycosides; Anti-Bacterial Agents; Butirosin Sulfate; Chemical Phenomena; Chemistry; Drug Resistance, Microbial; Gentamicins; Hygromycin B; Kanamycin; Neomycin; Paromomycin; Ribostamycin; Sisomicin; Streptomycin; Structure-Activity Relationship; Tobramycin

1974
Effect of selective decontamination on antimicrobial resistance in intensive care units: a systematic review and meta-analysis.
    The Lancet. Infectious diseases, 2013, Volume: 13, Issue:4

    Topics: Aminoglycosides; Amphotericin B; Anti-Bacterial Agents; Anti-Infective Agents, Local; Cephalosporins; Clinical Trials as Topic; Cross Infection; Decontamination; Digestive System; Disease Transmission, Infectious; Drug Resistance, Bacterial; Enterobacteriaceae; Europe; Fluoroquinolones; Gentamicins; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Intensive Care Units; Methicillin-Resistant Staphylococcus aureus; Neomycin; Nystatin; Odds Ratio; Oropharynx; Polymyxins; Prevalence; Primary Prevention; Pseudomonas aeruginosa; Randomized Controlled Trials as Topic; South Africa; Tobramycin; United States; Vancomycin

2013

Trials

2 trial(s) available for tobramycin and framycetin

ArticleYear
Low dose oral tobramycin treatment for selective decontamination of the digestive tract: a study in human volunteers.
    The Journal of antimicrobial chemotherapy, 1984, Volume: 13, Issue:5

    Topics: Adolescent; Adult; Digestive System; Drug Resistance, Microbial; Feces; Female; Gram-Negative Bacteria; Humans; Male; Middle Aged; Neomycin; Pharynx; Tobramycin

1984
Comparison of topical tobramycin-dexamethasone with dexamethasone-neomycin-polymyxin and neomycin-polymyxin-gramicidin for control of inflammation after cataract surgery: results of a multicenter, prospective, three-arm, randomized, double-masked, control
    Clinical therapeutics, 2004, Volume: 26, Issue:8

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Inflammatory Agents; Brazil; Cataract Extraction; Dexamethasone; Double-Blind Method; Drug Therapy, Combination; Europe; Female; Gramicidin; Humans; Inflammation; Male; Middle Aged; Neomycin; Polymyxins; Postoperative Complications; Prospective Studies; Tobramycin; Treatment Outcome

2004

Other Studies

110 other study(ies) available for tobramycin and framycetin

ArticleYear
Comparison of aminoglycoside antibiotics with respect to uptake and lethal activity in Escherichia coli.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:2

    Topics: Aminoglycosides; Anti-Bacterial Agents; Biological Transport; Escherichia coli; Indicators and Reagents; Kinetics; Structure-Activity Relationship

1987
Modeling RNA-ligand interactions: the Rev-binding element RNA-aminoglycoside complex.
    Journal of medicinal chemistry, 1998, Jan-15, Volume: 41, Issue:2

    Topics: Aminoglycosides; Anti-Bacterial Agents; Antiviral Agents; Binding Sites; Computer Simulation; Crystallography, X-Ray; Gene Products, rev; Humans; Ligands; Macromolecular Substances; Models, Chemical; Models, Molecular; Nucleic Acid Conformation; Protein Conformation; Rhinovirus; RNA, Viral; Structure-Activity Relationship

1998
Enhanced binding of aminoglycoside dimers to a "dimerized" A-site 16S rRNA construct.
    Bioorganic & medicinal chemistry letters, 2000, Jul-17, Volume: 10, Issue:14

    Topics: Aminoglycosides; Anti-Bacterial Agents; Binding Sites; Carbohydrate Conformation; Carbohydrate Sequence; Dimerization; Molecular Conformation; Molecular Sequence Data; Molecular Structure; RNA, Ribosomal, 16S

2000
Which aminoglycoside ring is most important for binding? A hydropathic analysis of gentamicin, paromomycin, and analogues.
    Bioorganic & medicinal chemistry letters, 2001, Jan-22, Volume: 11, Issue:2

    Topics: Algorithms; Aminoglycosides; Anti-Bacterial Agents; Binding Sites; Carbohydrate Conformation; Carbohydrate Sequence; Escherichia coli; Gentamicins; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Paromomycin; RNA, Ribosomal, 16S; Structure-Activity Relationship; Thermodynamics

2001
Binding of dimeric aminoglycosides to the HIV-1 rev responsive element (RRE) RNA construct.
    Bioorganic & medicinal chemistry letters, 2001, May-07, Volume: 11, Issue:9

    Topics: Anti-Bacterial Agents; Binding Sites; Carbohydrate Sequence; HIV-1; Models, Molecular; Molecular Sequence Data; Neomycin; Response Elements; RNA, Viral; Spectrometry, Fluorescence

2001
Novel synthesis and RNA-binding properties of aminoglycoside dimers conjugated via a naphthalene diimide-based intercalator.
    Bioorganic & medicinal chemistry letters, 2001, Nov-19, Volume: 11, Issue:22

    Topics: Aminoglycosides; Base Sequence; DNA; Imides; Intercalating Agents; Molecular Sequence Data; Naphthalenes; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Phenanthrolines; RNA-Binding Proteins; Structure-Activity Relationship

2001
Binding of aminoglycoside antibiotics with modified A-site 16S rRNA construct containing non-nucleotide linkers.
    Bioorganic & medicinal chemistry letters, 2002, Feb-11, Volume: 12, Issue:3

    Topics: Aminoglycosides; Anisotropy; Anti-Bacterial Agents; Base Pairing; Binding Sites; Cyclization; Drug Design; Indicators and Reagents; Kinetics; Nucleic Acid Conformation; RNA, Complementary; RNA, Ribosomal, 16S; Structure-Activity Relationship

2002
Decoding region bubble size and aminoglycoside antibiotic binding.
    Bioorganic & medicinal chemistry letters, 2002, Aug-19, Volume: 12, Issue:16

    Topics: Aminoglycosides; Anti-Bacterial Agents; Base Sequence; Fluorescence Polarization; Humans; Molecular Structure; Mutation; Nucleic Acid Conformation; RNA, Ribosomal

2002
Validation of automated docking programs for docking and database screening against RNA drug targets.
    Journal of medicinal chemistry, 2004, Aug-12, Volume: 47, Issue:17

    Topics: Algorithms; Aminoglycosides; Anti-Bacterial Agents; Binding Sites; Databases, Factual; Ligands; Models, Molecular; Nucleic Acid Conformation; Quantitative Structure-Activity Relationship; RNA; RNA, Ribosomal; Software

2004
Fluorescence resonance energy transfer studies of aminoglycoside binding to a T box antiterminator RNA.
    Bioorganic & medicinal chemistry letters, 2005, Apr-15, Volume: 15, Issue:8

    Topics: Aminoglycosides; Bacterial Proteins; Fluorescence Resonance Energy Transfer; RNA-Binding Proteins; RNA, Bacterial; T-Box Domain Proteins

2005
Aph(3')-IIc, an aminoglycoside resistance determinant from Stenotrophomonas maltophilia.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:1

    Topics: Aminoglycosides; Anti-Bacterial Agents; Butirosin Sulfate; Drug Resistance, Multiple, Bacterial; Escherichia coli; Gram-Negative Bacterial Infections; Humans; Kanamycin; Kanamycin Kinase; Microbial Sensitivity Tests; Mutation; Neomycin; Stenotrophomonas maltophilia

2007
Overexpression and initial characterization of the chromosomal aminoglycoside 3'-O-phosphotransferase APH(3')-IIb from Pseudomonas aeruginosa.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:2

    Topics: Bacterial Proteins; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Kanamycin Kinase; Kinetics; Phosphorylation; Pseudomonas aeruginosa

2007
Coproduction of novel 16S rRNA methylase RmtD and metallo-beta-lactamase SPM-1 in a panresistant Pseudomonas aeruginosa isolate from Brazil.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:3

    Topics: Amino Acid Sequence; Aminoglycosides; beta-Lactamases; Brazil; Carbapenems; Cloning, Molecular; Drug Resistance, Multiple, Bacterial; Methyltransferases; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Pseudomonas aeruginosa; Pseudomonas Infections

2007
Novel plasmid-mediated 16S rRNA m1A1408 methyltransferase, NpmA, found in a clinically isolated Escherichia coli strain resistant to structurally diverse aminoglycosides.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12

    Topics: Amino Acid Sequence; Aminoglycosides; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Methyltransferases; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Plasmids; Protein Binding; Ribosome Subunits, Small; RNA, Ribosomal, 16S; Sequence Homology, Amino Acid

2007
AAC(6')-Iaf, a novel aminoglycoside 6'-N-acetyltransferase from multidrug-resistant Pseudomonas aeruginosa clinical isolates.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:6

    Topics: Acetylation; Acetyltransferases; Aminoglycosides; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Integrons; Microbial Sensitivity Tests; Pseudomonas aeruginosa

2009
Design and implementation of an ribonucleic acid (RNA) directed fragment library.
    Journal of medicinal chemistry, 2009, Jun-25, Volume: 52, Issue:12

    Topics: Binding Sites; Chemistry, Physical; Databases, Factual; Drug Design; Ligands; Magnetic Resonance Spectroscopy; Molecular Weight; Organic Chemicals; Quality Control; RNA; Small Molecule Libraries

2009
ACHN-490, a neoglycoside with potent in vitro activity against multidrug-resistant Klebsiella pneumoniae isolates.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:10

    Topics: Aminoglycosides; Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Structure

2009
Synthesis and antimicrobial evaluation of amphiphilic neamine derivatives.
    Journal of medicinal chemistry, 2010, Jan-14, Volume: 53, Issue:1

    Topics: Anti-Bacterial Agents; Calorimetry; Framycetin; Gram-Negative Bacteria; Microbial Sensitivity Tests; Molecular Structure; Staphylococcus aureus; Stereoisomerism; Structure-Activity Relationship

2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Homozygous triplicate mutations in three 16S rRNA genes responsible for high-level aminoglycoside resistance in Nocardia farcinica clinical isolates from a Canada-wide bovine mastitis epizootic.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:6

    Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Base Sequence; Canada; Cattle; DNA Primers; Drug Resistance, Bacterial; Female; Genes, Bacterial; Homozygote; In Vitro Techniques; Mastitis, Bovine; Microbial Sensitivity Tests; Nocardia; Nocardia Infections; Point Mutation; RNA, Bacterial; RNA, Ribosomal, 16S

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
Pre-microRNA binding aminoglycosides and antitumor drugs as inhibitors of Dicer catalyzed microRNA processing.
    Bioorganic & medicinal chemistry letters, 2012, Feb-15, Volume: 22, Issue:4

    Topics: Aminoglycosides; Antineoplastic Agents; Base Sequence; DEAD-box RNA Helicases; Humans; MicroRNAs; Models, Biological; Molecular Sequence Data; Ribonuclease III; RNA Processing, Post-Transcriptional

2012
Tuning the antibacterial activity of amphiphilic neamine derivatives and comparison to paromamine homologues.
    Journal of medicinal chemistry, 2013, Oct-10, Volume: 56, Issue:19

    Topics: Aminoglycosides; Anti-Bacterial Agents; Drug Resistance, Bacterial; Framycetin; Gram-Negative Bacteria; Microbial Sensitivity Tests; Naphthalenes; Staphylococcus aureus; Structure-Activity Relationship

2013
Discovery of two aminoglycoside antibiotics as inhibitors targeting the menin-mixed lineage leukaemia interface.
    Bioorganic & medicinal chemistry letters, 2014, May-01, Volume: 24, Issue:9

    Topics: Anti-Bacterial Agents; Humans; Leukemia; Models, Molecular; Myeloid-Lymphoid Leukemia Protein; Neomycin; Protein Binding; Protein Interaction Maps; Proto-Oncogene Proteins; Tobramycin

2014
New Broad-Spectrum Antibacterial Amphiphilic Aminoglycosides Active against Resistant Bacteria: From Neamine Derivatives to Smaller Neosamine Analogues.
    Journal of medicinal chemistry, 2016, Oct-27, Volume: 59, Issue:20

    Topics: Aminoglycosides; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Framycetin; Glucosamine; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Surface-Active Agents

2016
Broad-spectrum antibacterial amphiphilic aminoglycosides: A new focus on the structure of the lipophilic groups extends the series of active dialkyl neamines.
    European journal of medicinal chemistry, 2018, Sep-05, Volume: 157

    Topics: Aminoglycosides; Anti-Bacterial Agents; Cell Survival; Dose-Response Relationship, Drug; Eukaryotic Cells; Framycetin; Humans; Microbial Sensitivity Tests; Molecular Structure; Pseudomonas aeruginosa; Structure-Activity Relationship; Surface-Active Agents

2018
Aminoglycoside 6'-N-acetyl-transferase of Pseudomonas aeruginosa: structural requirements of substrate.
    The Journal of antibiotics, 1975, Volume: 28, Issue:6

    Topics: Acetylation; Acetyltransferases; Amikacin; Aminoglycosides; Butirosin Sulfate; Chemical Phenomena; Chemistry; Gentamicins; Kanamycin; Microbial Sensitivity Tests; Neomycin; Pseudomonas aeruginosa; Ribostamycin; Tobramycin

1975
[Mechanisms of inactivation of aminosides. Relationship to phenotype in Gram negative bacilli].
    La Nouvelle presse medicale, 1975, Sep-20, Volume: 4, Issue:30

    Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Binding Sites; Butirosin Sulfate; Drug Resistance, Microbial; Enterobacteriaceae; Framycetin; Gentamicins; Kanamycin; Paromomycin; Phenotype; R Factors; Sisomicin; Structure-Activity Relationship; Tobramycin

1975
Gentamicin resistance in Staphylococcus aureus.
    Lancet (London, England), 1976, Jan-03, Volume: 1, Issue:7949

    Topics: Anti-Bacterial Agents; Drug Resistance, Microbial; Gentamicins; Humans; Kanamycin; Neomycin; Staphylococcus; Staphylococcus aureus; Streptomycin; Tobramycin

1976
Amikacin, an aminoglycoside with marked activity against antibiotic-resistant clinical isolates.
    The Journal of infectious diseases, 1976, Volume: 134 SUPPL

    Topics: Acinetobacter; Alcaligenes; Amikacin; Bacteria; Butirosin Sulfate; Dibekacin; Drug Resistance, Microbial; Enterobacteriaceae; Flavobacterium; Gentamicins; Kanamycin; Neomycin; Paromomycin; Pseudomonas; Ribostamycin; Staphylococcus; Tobramycin

1976
In vitro activity of amikacin and ten other aminoglycoside antibiotics against gentamicin-resistant bacterial strains.
    The Journal of infectious diseases, 1976, Volume: 134 SUPPL

    Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Butirosin Sulfate; Drug Resistance, Microbial; Enterobacteriaceae; Gentamicins; Kanamycin; Neomycin; Paromomycin; Pseudomonas aeruginosa; Ribostamycin; Sisomicin; Streptomycin; Tobramycin

1976
Drug toxicity of the inner ear.
    The Medical clinics of North America, 1979, Volume: 63, Issue:2

    Topics: Animals; Chloroquine; Dihydrostreptomycin Sulfate; Ethacrynic Acid; Furosemide; Gentamicins; Humans; Kanamycin; Labyrinth Diseases; Neomycin; Quinine; Salicylates; Streptomycin; Tobramycin

1979
Renal transport of organic acids and bases in aminoglycoside nephrotoxicity.
    Antimicrobial agents and chemotherapy, 1979, Volume: 16, Issue:2

    Topics: Acute Kidney Injury; Aminoglycosides; Animals; Biological Transport; Gentamicins; Kidney; Kidney Function Tests; Kidney Tubular Necrosis, Acute; Male; Neomycin; Niacinamide; p-Aminohippuric Acid; Rats; Tobramycin

1979
Cross-sensitivity within the neomycin group of antibiotics.
    Acta dermato-venereologica. Supplementum, 1979, Volume: 59, Issue:85

    Topics: Aminoglycosides; Anti-Bacterial Agents; Cross Reactions; Drug Hypersensitivity; Gentamicins; Humans; Kanamycin; Neomycin; Netilmicin; Sisomicin; Spectinomycin; Tobramycin

1979
Characterization of a nosocomially significant, multiple drug-resistant strain of Serratia marcescens.
    Chemotherapy, 1976, Volume: 22, Issue:5

    Topics: Ampicillin; Carbenicillin; Chloramphenicol; DNA, Bacterial; DNA, Circular; Gentamicins; Humans; Kanamycin; Nalidixic Acid; Neomycin; Penicillin Resistance; Polymyxins; Serratia marcescens; Streptomycin; Sulfonamides; Tobramycin

1976
Tobramycin and neuromuscular transmission in the rat isolated phrenic nerve-diaphragm preparation.
    British journal of anaesthesia, 1978, Volume: 50, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Gentamicins; In Vitro Techniques; Male; Muscle Contraction; Neomycin; Neuromuscular Junction; Rats; Streptomycin; Synaptic Transmission; Tobramycin

1978
The in vitro activity of apramycin, a new aminocyclitol antibiotic.
    The Journal of antimicrobial chemotherapy, 1977, Volume: 3, Issue:6

    Topics: Anti-Bacterial Agents; Bacteria; Drug Resistance, Microbial; Escherichia coli; Microbial Sensitivity Tests; Nebramycin; Neomycin; Streptomycin

1977
Effects of sputum from patients with cystic fibrosis on the activity in vitro of 5 antimicrobial drugs on Pseudomonas aeruginosa.
    The American review of respiratory disease, 1978, Volume: 117, Issue:1

    Topics: Anti-Bacterial Agents; Carbenicillin; Cystic Fibrosis; Gentamicins; Humans; Microbial Sensitivity Tests; Neomycin; Polymyxin B; Pseudomonas aeruginosa; Sputum; Tobramycin

1978
The effect of topical application of antibiotics on the cerebral cortex: an experimental update.
    Journal of neurosurgery, 1979, Volume: 50, Issue:6

    Topics: Administration, Topical; Amikacin; Animals; Anti-Bacterial Agents; Carbenicillin; Cats; Cephalothin; Cerebral Cortex; Electroencephalography; Gentamicins; Kanamycin; Methicillin; Neomycin; Penicillins; Seizures; Time Factors; Tobramycin

1979
[Analysis of biospecific complexes by electrophoresis: antibiotics specific to bacterial ribosomes].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1976, Sep-20, Volume: 283, Issue:5

    Topics: Anti-Bacterial Agents; Binding Sites; Chloramphenicol; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gentamicins; Neomycin; Ribosomes; Streptomycin; Tobramycin

1976
Suceptibility of aminoglycoside-resistant gram-negative bacilli to amikacin: delineation of individual resistance patterns.
    The Journal of infectious diseases, 1976, Volume: 134 SUPPL

    Topics: Amikacin; Aminoglycosides; Drug Resistance, Microbial; Enterobacteriaceae; Gentamicins; Kanamycin; Moraxella; Neomycin; Paromomycin; Pseudomonas aeruginosa; Tobramycin

1976
Tobramycin-neomycin cross-sensitivity.
    Contact dermatitis, 1977, Volume: 3, Issue:3

    Topics: Anti-Bacterial Agents; Chemical Phenomena; Chemistry; Cross Reactions; Humans; Hypersensitivity; Neomycin; Patch Tests; Tobramycin

1977
Aminoglycosides: do we need new agents?
    Drugs, 1976, Volume: 12, Issue:3

    Topics: Aminoglycosides; Anti-Bacterial Agents; Drug Resistance, Microbial; Gentamicins; Humans; Kanamycin; Neomycin; Streptomycin; Tobramycin

1976
[ANT(4')I: a new aminoglycoside nucleotidyltransferase found in "staphylococcus aureus" (author's transl)].
    Annales de microbiologie, 1976, Volume: 127, Issue:3

    Topics: Aminoglycosides; Anti-Bacterial Agents; Chemical Phenomena; Chemistry; Drug Resistance, Microbial; Kanamycin; Neomycin; Nucleotidyltransferases; Paromomycin; Staphylococcus aureus; Tobramycin

1976
Ion-exchange chromatography of aminoglycoside antibodies.
    Methods in enzymology, 1975, Volume: 43

    Topics: Aminoglycosides; Anti-Bacterial Agents; Biological Assay; Chromatography, Ion Exchange; Gentamicins; Kanamycin; Klebsiella pneumoniae; Nebramycin; Neomycin; Paromomycin; Streptomyces

1975
Structure-function relationships for the effects of various aminoglycoside antibiotics on dispersed bovine parathyroid cells.
    Endocrinology, 1992, Volume: 131, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Calcium; Cattle; Cyclic AMP; Dopamine; Framycetin; Gentamicins; Parathyroid Glands; Parathyroid Hormone; Paromomycin; Structure-Activity Relationship; Tobramycin

1992
Interaction of antibiotics with A- and P-site-specific bases in 16S ribosomal RNA.
    The EMBO journal, 1991, Volume: 10, Issue:10

    Topics: Aminoglycosides; Anti-Bacterial Agents; Autoradiography; Escherichia coli; Nebramycin; Neomycin; Nucleic Acid Conformation; Nucleic Acid Hybridization; RNA, Ribosomal, 16S

1991
Electrochemical and spectroscopic characterization of the 7Fe form of ferredoxin III from Desulfovibrio africanus.
    The Biochemical journal, 1989, Nov-15, Volume: 264, Issue:1

    Topics: Amino Acid Sequence; Circular Dichroism; Desulfovibrio; Electron Spin Resonance Spectroscopy; Ferredoxins; Hydrogen-Ion Concentration; Iron; Magnetics; Molecular Sequence Data; Neomycin; Oxidation-Reduction; Spectrum Analysis; Tobramycin

1989
Infiltrative keratitis associated with disposable soft contact lenses. Case reports.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1989, Volume: 107, Issue:3

    Topics: Adult; Bacitracin; Cefazolin; Contact Lenses, Hydrophilic; Drug Combinations; Drug Therapy, Combination; Female; Humans; Keratitis; Neomycin; Ophthalmic Solutions; Polymyxin B; Tobramycin

1989
Influence of faeces on the activity of antimicrobial agents used for decontamination of the alimentary canal.
    Scandinavian journal of infectious diseases, 1985, Volume: 17, Issue:3

    Topics: Anti-Bacterial Agents; Aztreonam; Ciprofloxacin; Colistin; Digestive System; Dose-Response Relationship, Drug; Feces; Humans; Nalidixic Acid; Neomycin; Norfloxacin; Pipemidic Acid; Quinolines; Tobramycin

1985
Characteristics of gentamicin uptake in the isolated crista ampullaris of the inner ear of the guinea pig.
    Biochemical pharmacology, 1987, Jan-01, Volume: 36, Issue:1

    Topics: Animals; Binding, Competitive; Ear, Inner; Gentamicins; Guinea Pigs; Kinetics; Mathematics; Neomycin; Netilmicin; Polyamines; Temperature; Time Factors; Tobramycin

1987
Comparative effects of aminoglycosides on renal cortical and urinary phospholipids in the rat.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1986, Volume: 182, Issue:1

    Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Gentamicins; Humans; Kidney Cortex; Lysosomes; Male; Neomycin; Netilmicin; Phospholipids; Rats; Rats, Inbred Strains; Tobramycin

1986
Effect of aminoglycoside antibiotics on cellular functions of kidney epithelial cell line (LLC-PK1): a model system for aminoglycoside nephrotoxicity.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 230, Issue:3

    Topics: Adenosine Triphosphate; Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Cell Count; Cell Line; Cyclic AMP; Epithelial Cells; Gentamicins; Kidney; Microscopy, Electron; Neomycin; Swine; Tobramycin

1984
The comparative neuromuscular blocking effects of some aminoglycoside antibiotics.
    Acta anaesthesiologica Belgica, 1980, Volume: 31, Issue:4

    Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Diaphragm; Drug Synergism; Gentamicins; Neomycin; Netilmicin; Neuromuscular Blocking Agents; Pancuronium; Phrenic Nerve; Rats; Tobramycin; Vecuronium Bromide

1980
Aminoglycoside-induced cochlear pathology in man.
    Acta oto-laryngologica. Supplementum, 1981, Volume: 383

    Topics: Adult; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Child; Cochlea; Female; Gentamicins; Hair Cells, Auditory; Hearing Loss, Bilateral; Humans; Labyrinth Diseases; Male; Middle Aged; Neomycin; Organ of Corti; Spiral Lamina; Temporal Bone; Tobramycin

1981
Resistance to apramycin in Escherichia coli isolated from animals: detection of a novel aminoglycoside-modifying enzyme.
    Journal of general microbiology, 1984, Volume: 130, Issue:3

    Topics: Acetyltransferases; Aminoglycosides; Animals; Anti-Bacterial Agents; Drug Resistance, Microbial; Escherichia coli; Nebramycin; Neomycin; Plasmids

1984
Quantitation of amikacin, kanamycin, neomycin, and tobramycin in pharmaceutical dosage forms using the Hantzsch reaction.
    Journal of pharmaceutical sciences, 1983, Volume: 72, Issue:12

    Topics: Amikacin; Anti-Bacterial Agents; Capsules; Chemistry, Pharmaceutical; Excipients; Injections; Kanamycin; Neomycin; Solutions; Spectrophotometry; Tablets; Tobramycin

1983
Application of o-hydroxyhydroquinonephthalein-uranium (VI) complex to determination of neomycin and toburamycin.
    Chemical & pharmaceutical bulletin, 1984, Volume: 32, Issue:3

    Topics: Coloring Agents; Humans; Hydroquinones; Neomycin; Saliva; Spectrophotometry, Ultraviolet; Tobramycin; Uranium

1984
An improved method using acetyl-coenzyme A regeneration for the enzymic inactivation of aminoglycosides prior to sterility testing.
    The Journal of applied bacteriology, 1982, Volume: 53, Issue:2

    Topics: Acetyl Coenzyme A; Acetylation; Aminoglycosides; Anti-Bacterial Agents; Drug Contamination; Escherichia coli; Gentamicins; Kanamycin; Methods; Neomycin; Phosphate Acetyltransferase; Streptomycin; Tobramycin

1982
In vitro response of rat and human kidney lysosomes to aminoglycosides.
    Biochemical pharmacology, 1982, Nov-01, Volume: 31, Issue:21

    Topics: Acetylglucosaminidase; Aminoglycosides; Animals; Anti-Bacterial Agents; Female; Gentamicins; Hexosaminidases; Humans; Kidney Cortex; Lysosomes; Male; Neomycin; Polyamines; Rats; Streptomycin; Tobramycin

1982
Characterization of the tobramycin-kanamycin-neomycin resistance plasmid in Staphylococcus epidermidis.
    The Journal of antibiotics, 1980, Volume: 33, Issue:8

    Topics: Anti-Bacterial Agents; Kanamycin; Kinetics; Molecular Weight; Neomycin; R Factors; Staphylococcus; Tobramycin

1980
Effects of gentamicin, neomycin and tobramycin on renal calcium and magnesium handling in two rat strains.
    Clinical and experimental pharmacology & physiology, 1994, Volume: 21, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Calcium; Gentamicins; Glomerular Filtration Rate; Inulin; Kidney; Magnesium; Male; Neomycin; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Species Specificity; Tobramycin; Ultrafiltration

1994
RNA molecules that specifically and stoichiometrically bind aminoglycoside antibiotics with high affinities.
    Biochemistry, 1996, Sep-24, Volume: 35, Issue:38

    Topics: Anti-Bacterial Agents; Base Sequence; Binding, Competitive; Carbohydrate Sequence; Edetic Acid; Erythromycin; Ferrous Compounds; Fluorescence Polarization; Fluorescent Dyes; Framycetin; Gentamicins; Molecular Sequence Data; Molecular Structure; Nucleic Acid Conformation; Oligoribonucleotides; Rhodamines; RNA; Tobramycin

1996
Block of P/Q-type calcium channels by therapeutic concentrations of aminoglycoside antibiotics.
    Biochemistry, 1996, Nov-19, Volume: 35, Issue:46

    Topics: Animals; Anti-Bacterial Agents; Barium; Calcium Channel Blockers; Calcium Channels; Female; Guinea Pigs; Kanamycin; Mollusk Venoms; Neomycin; omega-Conotoxins; Peptides; Streptomycin; Tobramycin; Xenopus

1996
[Characteristics of Streptomyces kanamyceticus mutants resistant to aminoglycoside antibiotics].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1996, Volume: 41, Issue:6

    Topics: Anti-Bacterial Agents; Drug Resistance, Microbial; Genes, Bacterial; Genetic Variation; Gentamicins; Kanamycin; Kanamycin Resistance; Microbial Sensitivity Tests; Mutation; Nebramycin; Neomycin; Spores, Bacterial; Streptomyces

1996
The antibiotic neomycin abolishes directional selectivity in rabbit retinal ganglion cells.
    General pharmacology, 1996, Volume: 27, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Calcium Channel Blockers; Gentamicins; In Vitro Techniques; Neomycin; Photic Stimulation; Rabbits; Retinal Ganglion Cells; Streptomycin; Tobramycin

1996
Minimal RNA constructs that specifically bind aminoglycoside antibiotics with high affinities.
    Biochemistry, 1998, Jan-13, Volume: 37, Issue:2

    Topics: Aminoglycosides; Anti-Bacterial Agents; Binding Sites; Gentamicins; Kanamycin; Neomycin; Nucleic Acid Conformation; RNA; Structure-Activity Relationship; Tobramycin

1998
Incidence of antibiotic resistance in fecal Escherichia coli isolated from commercial swine farms.
    Journal of animal science, 1998, Volume: 76, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Carbadox; Chi-Square Distribution; Drug Resistance, Microbial; Escherichia coli; Feces; Female; Gentamicins; Male; Microbial Sensitivity Tests; Nebramycin; Neomycin; Oxytetracycline; Swine

1998
Aminoglycoside binding to the hammerhead ribozyme: a general model for the interaction of cationic antibiotics with RNA.
    Journal of molecular biology, 1998, Mar-13, Volume: 276, Issue:5

    Topics: Anti-Bacterial Agents; Binding Sites; Carbohydrate Conformation; Carbohydrate Sequence; Framycetin; Magnesium; Models, Molecular; Molecular Sequence Data; Molecular Structure; Nucleic Acid Conformation; RNA; RNA, Catalytic; Solutions; Thermodynamics; Tobramycin

1998
Analysis of neomycin, kanamycin, tobramycin and amikacin resistance mechanisms in gentamicin-resistant isolates of Enterobacteriaceae.
    Journal of medical microbiology, 1998, Volume: 47, Issue:11

    Topics: Amikacin; Anti-Bacterial Agents; DNA, Bacterial; Drug Resistance, Microbial; Enterobacteriaceae; Ethidium; Fluorescent Dyes; Gentamicins; Humans; Kanamycin Resistance; Microbial Sensitivity Tests; Neomycin; R Factors; Tobramycin

1998
Docking of cationic antibiotics to negatively charged pockets in RNA folds.
    Journal of medicinal chemistry, 1999, Apr-08, Volume: 42, Issue:7

    Topics: Anti-Bacterial Agents; Binding Sites; HIV-1; Kanamycin; Models, Molecular; Neomycin; Protein Conformation; Response Elements; RNA; RNA, Ribosomal, 16S; Tobramycin

1999
Saccharide-RNA recognition in a complex formed between neomycin B and an RNA aptamer.
    Structure (London, England : 1993), 1999, Jul-15, Volume: 7, Issue:7

    Topics: Anti-Bacterial Agents; Carbohydrate Sequence; Framycetin; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Oligosaccharides; Protons; RNA; Tobramycin

1999
Enhanced RNA binding of dimerized aminoglycosides.
    Bioorganic & medicinal chemistry, 1999, Volume: 7, Issue:7

    Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Base Sequence; Deoxyribonucleases, Type II Site-Specific; Dimerization; Disulfides; Kinetics; Neomycin; Nucleic Acid Conformation; Osmolar Concentration; RNA; RNA, Catalytic; Tetrahymena; Tobramycin

1999
Tympanostomy tubes and otic suspensions: do they reach the middle ear space?
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2000, Volume: 122, Issue:3

    Topics: Administration, Topical; Anti-Bacterial Agents; Ciprofloxacin; Dexamethasone; Drug Combinations; Ear, Middle; Humans; Hydrocortisone; Middle Ear Ventilation; Neomycin; Otitis Media, Suppurative; Polymyxin B; Postoperative Complications; Therapeutic Irrigation; Tobramycin

2000
A teratological study of aminoglycoside antibiotic treatment during pregnancy.
    Scandinavian journal of infectious diseases, 2000, Volume: 32, Issue:3

    Topics: Abnormalities, Drug-Induced; Anti-Bacterial Agents; Case-Control Studies; Female; Gentamicins; Humans; Infant, Newborn; Neomycin; Pregnancy; Pregnancy Complications, Infectious; Risk; Streptomycin; Teratogens; Tobramycin

2000
Antimicrobial resistance in enteric porcine Escherichia coli strains in Spain.
    The Veterinary record, 2000, Jun-10, Volume: 146, Issue:24

    Topics: Amoxicillin; Animals; Animals, Newborn; Anti-Bacterial Agents; Cephalosporins; Colistin; Diarrhea; Drug Resistance, Microbial; Enrofloxacin; Escherichia coli; Escherichia coli Infections; Fluoroquinolones; Microbial Sensitivity Tests; Nebramycin; Neomycin; Quinolones; Spain; Swine; Swine Diseases

2000
Aminoglycoside antibiotics mediate context-dependent suppression of termination codons in a mammalian translation system.
    RNA (New York, N.Y.), 2000, Volume: 6, Issue:7

    Topics: Animals; Anti-Bacterial Agents; Cinnamates; Codon, Terminator; Dose-Response Relationship, Drug; Escherichia coli; Genes, Reporter; Gentamicins; Humans; Hygromycin B; Kanamycin; Neomycin; Paromomycin; Plasmids; Protein Biosynthesis; Rabbits; Reticulocytes; Ribosomes; RNA, Messenger; Sisomicin; Streptomycin; Tobramycin

2000
Inhibition of eukaryotic ribonuclease P activity by aminoglycosides: kinetic studies.
    FEBS letters, 2000, Nov-17, Volume: 485, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Binding, Competitive; Cations; Dictyostelium; Endoribonucleases; Enzyme Inhibitors; Gentamicins; Kanamycin; Kinetics; Magnesium; Mathematics; Neomycin; Paromomycin; Ribonuclease P; RNA, Catalytic; Static Electricity; Tobramycin

2000
Aminoglycoside binding to human and bacterial A-Site rRNA decoding region constructs.
    Bioorganic & medicinal chemistry, 2001, Volume: 9, Issue:10

    Topics: Algorithms; Aminoglycosides; Anti-Bacterial Agents; Bacteria; Fluorescence Polarization; Framycetin; Humans; Kanamycin; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; Paromomycin; Rhodamines; RNA, Ribosomal; RNA, Ribosomal, 16S; RNA, Ribosomal, 18S; Structure-Activity Relationship; Tobramycin

2001
Determination of ototoxicity of common otic drops using isolated cochlear outer hair cells.
    The Laryngoscope, 2001, Volume: 111, Issue:12

    Topics: Acetic Acid; Administration, Topical; Animals; Cell Size; Cell Survival; Cells, Cultured; Chinchilla; Drug Combinations; Gentamicins; Hair Cells, Auditory, Outer; Hydrocortisone; Neomycin; Polymyxin B; Tobramycin; Ultrasonography

2001
Stereospecificity of aminoglycoside-ribosomal interactions.
    Biochemistry, 2002, Aug-20, Volume: 41, Issue:33

    Topics: Anti-Bacterial Agents; Binding, Competitive; Fluorescence Polarization; Framycetin; Inhibitory Concentration 50; Microbial Sensitivity Tests; Oligoribonucleotides; Paromomycin; Protein Biosynthesis; Rhodamines; Ribosomes; RNA, Bacterial; RNA, Fungal; RNA, Ribosomal; Spectrometry, Fluorescence; Stereoisomerism; Tobramycin

2002
Resonance Rayleigh scattering spectra for studying the interaction of aminoglycoside antibiotics with pontamine sky blue and their analytical applications.
    Analytical and bioanalytical chemistry, 2003, Volume: 376, Issue:1

    Topics: Aminoglycosides; Anti-Bacterial Agents; Azo Compounds; Coloring Agents; Gentamicins; Hydrogen-Ion Concentration; Kanamycin; Molecular Structure; Neomycin; Scattering, Radiation; Spectrometry, Fluorescence; Tobramycin; Trypan Blue

2003
Selective gut decontamination.
    Critical care medicine, 2003, Volume: 31, Issue:11

    Topics: Anti-Bacterial Agents; Decontamination; Endotoxemia; Humans; Intestines; Neomycin; Randomized Controlled Trials as Topic; Tobramycin

2003
Characterization of antimicrobial resistant Salmonella Kinshasa from dairy calves in Texas.
    Letters in applied microbiology, 2004, Volume: 38, Issue:2

    Topics: Ampicillin; Animals; Anti-Bacterial Agents; Cattle; Chloramphenicol; Conjugation, Genetic; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Feces; Fluoroquinolones; Gene Transfer, Horizontal; Microbial Sensitivity Tests; Nebramycin; Neomycin; Oxytetracycline; Public Health; Risk Factors; Salmonella; Serotyping; Spectinomycin; Streptomycin; Sulfamethoxazole; Tetracycline; Texas

2004
From triplex to B-form duplex stabilization: reversal of target selectivity by aminoglycoside dimers.
    Bioorganic & medicinal chemistry letters, 2004, Sep-20, Volume: 14, Issue:18

    Topics: Calorimetry; Dimerization; DNA; Neomycin; Nucleic Acid Conformation; Structure-Activity Relationship; Tobramycin

2004
Aminoglycoside antibiotics aggregate to form starch-like fibers on negatively charged surfaces and on phage lambda-DNA.
    Langmuir : the ACS journal of surfaces and colloids, 2004, Oct-12, Volume: 20, Issue:21

    Topics: Aminoglycosides; Anti-Bacterial Agents; Bacteriophage lambda; Carbohydrate Conformation; Carbohydrate Sequence; DNA, Viral; Filtration; Kanamycin; Molecular Sequence Data; Neomycin; Particle Size; Static Electricity; Surface Properties; Tobramycin

2004
Kinetic mechanism of streptomycin adenylyltransferase from a recombinant Escherichia coli.
    Biotechnology letters, 2005, Volume: 27, Issue:7

    Topics: Adenosine Triphosphate; Diphosphates; Enzyme Inhibitors; Escherichia coli; Kinetics; Neomycin; Nucleotidyltransferases; Recombinant Proteins; Streptomycin; Tobramycin

2005
Fixed exanthema from systemic tobramycin.
    Journal of investigational allergology & clinical immunology, 2006, Volume: 16, Issue:4

    Topics: Aged; Aminoglycosides; Anti-Bacterial Agents; Cross Reactions; Drug Hypersensitivity; Exanthema; Female; Humans; Immunologic Tests; Neomycin; Ophthalmic Solutions; Skin Tests; Tobramycin

2006
Interaction of neomycin, tobramycin and amikacin with melanin in vitro in relation to aminoglycosides-induced ototoxicity.
    Die Pharmazie, 2007, Volume: 62, Issue:3

    Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Dihydroxyphenylalanine; Drug Interactions; Hearing Disorders; Indicators and Reagents; Kinetics; Melanins; Neomycin; Protein Binding; Tobramycin

2007
[The role of aminoglycoside--modifying enzymes in resistance of Gram-negative rods].
    Medycyna doswiadczalna i mikrobiologia, 2006, Volume: 58, Issue:4

    Topics: Acetyltransferases; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Gentamicins; Gram-Negative Bacteria; Humans; Kanamycin; Microbial Sensitivity Tests; Neomycin; Netilmicin; Phenotype; Pseudomonas aeruginosa; Tobramycin

2006
Identification of tobramycin impurities for quality control process monitoring using high-performance anion-exchange chromatography with integrated pulsed amperometric detection.
    Journal of pharmaceutical and biomedical analysis, 2008, Aug-05, Volume: 47, Issue:4-5

    Topics: Anti-Bacterial Agents; Chromatography, Ion Exchange; Drug Contamination; Electrochemistry; Fermentation; Hydrogen-Ion Concentration; Kanamycin; Nebramycin; Neomycin; Quality Control; Reference Standards; Streptomyces; Technology, Pharmaceutical; Tobramycin

2008
Two-dimensional combinatorial screening identifies specific aminoglycoside-RNA internal loop partners.
    Journal of the American Chemical Society, 2008, Aug-20, Volume: 130, Issue:33

    Topics: Alkynes; Aminoglycosides; Azides; Base Pairing; Carbohydrate Conformation; Combinatorial Chemistry Techniques; Framycetin; Kanamycin; Ligands; Nucleic Acid Conformation; Oligonucleotide Array Sequence Analysis; Oligonucleotides; Reverse Transcriptase Polymerase Chain Reaction; RNA; Small Molecule Libraries; Tobramycin; Transcription, Genetic

2008
[Study of cytotoxic and antiviral effects of some eye drops].
    Oftalmologia (Bucharest, Romania : 1990), 2008, Volume: 52, Issue:4

    Topics: Analgesics, Opioid; Androgens; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Atropine; Dexamethasone; Drug Therapy, Combination; Ethylmorphine; Glucocorticoids; Humans; Indomethacin; Keratitis, Herpetic; Nandrolone; Neomycin; Ophthalmic Solutions; Tobramycin; Treatment Outcome

2008
Cutaneous allergy testing in patients suspected of an allergic reaction to eye medication.
    Ophthalmic research, 2009, Volume: 41, Issue:4

    Topics: Anti-Bacterial Agents; Drug Hypersensitivity; Eye Diseases; Humans; Neomycin; Preservatives, Pharmaceutical; Retrospective Studies; Skin Tests; Thimerosal; Tobramycin

2009
Two-dimensional combinatorial screening of a bacterial rRNA A-site-like motif library: defining privileged asymmetric internal loops that bind aminoglycosides.
    Biochemistry, 2010, Mar-09, Volume: 49, Issue:9

    Topics: Amino Acyl-tRNA Synthetases; Aminoglycosides; Binding Sites; Combinatorial Chemistry Techniques; Drug Delivery Systems; Framycetin; Gene Library; Kanamycin; Nucleic Acid Conformation; Oligonucleotides; Reverse Transcriptase Polymerase Chain Reaction; RNA, Bacterial; RNA, Ribosomal, 16S; Tobramycin

2010
Cooperative, heparan sulfate-dependent cellular uptake of dimeric guanidinoglycosides.
    Chembiochem : a European journal of chemical biology, 2010, Nov-02, Volume: 11, Issue:16

    Topics: Animals; Biological Transport; CHO Cells; Cricetinae; Cricetulus; Dimerization; Flow Cytometry; Glycosides; Guanidine; Heparitin Sulfate; Neomycin; Paromomycin; Tobramycin

2010
Influence of charge and structure on the coordination chemistry of copper aminoglycosides.
    Dalton transactions (Cambridge, England : 2003), 2011, Feb-28, Volume: 40, Issue:8

    Topics: Aminoglycosides; Anti-Bacterial Agents; Binding Sites; Copper; Framycetin; Kanamycin; Magnetic Resonance Spectroscopy; Molecular Structure; Paromomycin; Spectrophotometry, Ultraviolet; Static Electricity; Tobramycin

2011
Synthesis, separation, and characterization of amphiphilic sulfated oligosaccharides enabled by reversed-phase ion pairing LC and LC-MS methods.
    Carbohydrate research, 2011, Dec-13, Volume: 346, Issue:17

    Topics: Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Kanamycin; Nebramycin; Neomycin; Spectrometry, Mass, Electrospray Ionization; Sulfuric Acid Esters

2011
Identification of a novel 6'-N-aminoglycoside acetyltransferase, AAC(6')-Iak, from a multidrug-resistant clinical isolate of Stenotrophomonas maltophilia.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:10

    Topics: Acetyltransferases; Anti-Bacterial Agents; Dibekacin; Drug Resistance, Multiple, Bacterial; Microbial Sensitivity Tests; Neomycin; Netilmicin; Sisomicin; Stenotrophomonas maltophilia; Tobramycin

2014
Validated spectrofluorimetric method for determination of selected aminoglycosides.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2015, Jan-25, Volume: 135

    Topics: Aminoglycosides; Dosage Forms; Indicators and Reagents; Kanamycin; Limit of Detection; Neomycin; Reproducibility of Results; Spectrometry, Fluorescence; Tobramycin

2015
Development of spectrofluorimetric method for determination of certain aminoglycoside drugs in dosage forms and human plasma through condensation with ninhydrin and phenyl acetaldehyde.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2015, Feb-05, Volume: 136 Pt C

    Topics: Acetaldehyde; Aminoglycosides; Blood Chemical Analysis; Dosage Forms; Drug Monitoring; Humans; Nanoconjugates; Neomycin; Ninhydrin; Ointments; Ophthalmic Solutions; Plasma; Solutions; Spectrometry, Fluorescence; Tablets; Tobramycin

2015
Oncogenic MicroRNAs Biogenesis as a Drug Target: Structure-Activity Relationship Studies on New Aminoglycoside Conjugates.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2016, Apr-04, Volume: 22, Issue:15

    Topics: Aminoglycosides; Biological Evolution; Drug Delivery Systems; Humans; MicroRNAs; Models, Molecular; Nebramycin; Neomycin; Stomach Neoplasms; Structure-Activity Relationship

2016
HEI-OC1 cells as a model for investigating drug cytotoxicity.
    Hearing research, 2016, Volume: 335

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Apoptosis; Autophagy; Cell Line; Cell Proliferation; Cell Survival; Cellular Senescence; Cisplatin; Dexamethasone; Drug Evaluation, Preclinical; Gentamicins; Hair Cells, Auditory; HEK293 Cells; HeLa Cells; Humans; Mice; Neomycin; Organ of Corti; Penicillins; Reactive Oxygen Species; Streptomycin; Tobramycin

2016
Urea-formaldehyde monolithic column for hydrophilic in-tube solid-phase microextraction of aminoglycosides.
    Journal of chromatography. A, 2017, Feb-17, Volume: 1485

    Topics: Adsorption; Aminoglycosides; Animals; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Hydrophobic and Hydrophilic Interactions; Limit of Detection; Neomycin; Polymers; Solid Phase Microextraction; Streptomycin; Tilapia; Tobramycin; Water

2017
Structure-Based Design and Synthesis of Apramycin-Paromomycin Analogues: Importance of the Configuration at the 6'-Position and Differences between the 6'-Amino and Hydroxy Series.
    Journal of the American Chemical Society, 2017, 10-18, Volume: 139, Issue:41

    Topics: Anti-Bacterial Agents; Nebramycin; Neomycin; Paromomycin; Ribosomes

2017
A SERS-based multiple immuno-nanoprobe for ultrasensitive detection of neomycin and quinolone antibiotics via a lateral flow assay.
    Mikrochimica acta, 2018, 01-06, Volume: 185, Issue:2

    Topics: Anti-Bacterial Agents; Antibodies, Monoclonal; Biological Assay; Biosensing Techniques; Contrast Media; Gentamicins; Gold; Limit of Detection; Metal Nanoparticles; Neomycin; Particle Size; Quinolones; Sensitivity and Specificity; Spectrum Analysis, Raman; Streptomycin; Surface Properties; Tobramycin

2018
Lower ototoxicity and absence of hidden hearing loss point to gentamicin C1a and apramycin as promising antibiotics for clinical use.
    Scientific reports, 2019, 02-20, Volume: 9, Issue:1

    Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Cell Line; Drug Resistance, Bacterial; Gentamicins; Guinea Pigs; Hair Cells, Auditory, Inner; Hearing Loss; Humans; Nebramycin; Neomycin; Ototoxicity; Protein Synthesis Inhibitors; Round Window, Ear

2019
Antimicrobial Activity of a Triple Antibiotic Combination Toward Ocular Pseudomonas aeruginosa Clinical Isolates.
    Translational vision science & technology, 2022, 05-02, Volume: 11, Issue:5

    Topics: Anti-Bacterial Agents; Bacitracin; Drug Combinations; Erythromycin; Framycetin; Humans; Keratitis; Levofloxacin; Moxifloxacin; Polymyxin B; Pseudomonas aeruginosa; Pseudomonas Infections; Rifampin; Tobramycin; Trimethoprim

2022
Mechanisms of IS
    Microbiology spectrum, 2022, 10-26, Volume: 10, Issue:5

    Topics: Acinetobacter baumannii; Anti-Bacterial Agents; DNA Transposable Elements; Drug Resistance, Bacterial; Neomycin; Tobramycin

2022