Page last updated: 2024-08-23

tobramycin and aztreonam

tobramycin has been researched along with aztreonam in 111 studies

Research

Studies (111)

Timeframe	Studies, this research(%)	All Research%
pre-1990	22 (19.82)	18.7374
1990's	7 (6.31)	18.2507
2000's	40 (36.04)	29.6817
2010's	35 (31.53)	24.3611
2020's	7 (6.31)	2.80

Authors

Authors	Studies
Kawakami, Y; Kobayashi, Y; Uchida, H	1
Moss, RB	1
Fasano, D; Palù, P; Papadia, F	1
Apice, G; Beneduce, G; Bruni, GS; D'Aprile, M; Pergola, M; Perna, M; Silvestro, P; Villari, P	1
Birolini, D; de Souza, OS; Moraes, MF	1
Ramirez-Ronda, CH; Rivera-Vazquez, CR; Rodriguez, JR; Saavedra, S	1
David Vera, C; Gallego, J; Gobernado, M; Jiménez Cruz, JF; Llopis, B; Ruiz, JL; Server, G; Vidal, J	1
Lerk, CF; Stoutenbeek, CP; van Saene, HK; van Saene, JJ	1
Chalkley, LJ; Koornhof, HJ	1
Bosso, JA; Matsen, JM; Saxon, BA	1
Black, PG; Bosso, JA	1
Elliott, CR; Pater, JL	1
Bosso, JA; Walker, KB	1
Chin, NX; Labthavikul, P; Neu, HC	1
Chin, NX; Labthavikul, P; Neu, HC; Saha, G	1
Bell, RG; Lipford, LC; Massanari, MJ; Riley, CM	1
Becker, A; Burdge, RE; Ellington, LL; Greenberg, RN; Perry, CR; Vossen, MK	1
Schentag, JJ; Simons, GW; Smith, IL; Swanson, DJ; Vari, AJ; Vigano, A; Winslade, NE	1
Kany, RJ; Zar, FA	1
Ramirez-Ronda, CH; Rodriguez, JR	1
Nevárez, M; Ramírez-Ronda, CH; Rodríguez, JR	1
Hazenberg, MP; Pennock-Schröder, AM; van de Merwe, JP	1
Fass, RJ; Helsel, VL	1
Pennington, JE; Schiff, JB	1
Marks, MI; Scribner, RK; Stutman, HR; Welch, DF	1
Daenen, SM; de Vries-Hospers, HG; Erjavec, Z; Halie, MR; van der Waaij, D; van Kamp, H	1
Danko, LS; Greenberg, RN; Meade, DW	1
Deguchi, K; Fukayama, S; Ishihara, R; Koguchi, M; Oda, S; Suzuki, Y	1
Flynn, CM; Johnson, DM; Jones, RN	1
Ballow, CH; Booker, BM; Forrest, A; Schentag, JJ; Smith, PF	1
Jones, RN; Rhomberg, PR	1
Tiddens, H	1
Dudley, MN; Griffith, DC; Miller, CE; Nolan, TG; Sabet, M; Senekeo-Effenberger, K	1
Martin, L; Rajendran, R; Ramage, G; Rinaldi, A; Smith, K; Walker, D	1
Ballmann, M; Geller, DE; Smyth, A	1
Hewer, SL	1
Angyalosi, G; Balp, MM; Capkun-Niggli, G; Doering, G; Higashi, K; Jansen, JP; Littlewood, KJ; Tiddens, HA	1
Griffin, EF; Moreau-Marquis, S; O'Toole, GA; Schwartzman, JD; Stanton, BA; Yu, Q	1
Assael, BM; Bilton, D; Bresnik, M; Chiron, R; Fayon, M; Fischer, R; Knoop, C; LaRosa, M; Lewis, SA; McElvaney, N; Montgomery, AB; Oermann, CM; Pressler, T	1
Bell, SC; Goss, CH	1
Cantón, R; Girón, RM; Lamas, A; Máiz, L; Mensa, J; Olveira, C; Pastor, D; Quintana, E	1
Chmiel, JF; Forssén, AV; Kim, SH; Moskowitz, SM; Nichols, DP; Nick, JA; Saavedra, MT; Saiman, L; Taylor-Cousar, JL	1
Goss, CH; Quon, BS; Ramsey, BW	1
Fiel, SB	1
Coutermarsh, B; Moreau-Marquis, S; Stanton, BA	1
Bos, AC; Devadason, S; Janssens, HM; Mouton, JW; Tiddens, HA	1
Dasenbrook, EC; Konstan, MW; VanDevanter, DR	1
Daines, CL; Farquharson, R; Higuchi, K; Schechter, MS; Trueman, D	1
Beaudoin, T; LiPuma, JJ; Tom, SK; Waters, V; Yau, YC	1
Gholipourmalekabadi, M; Hashemi, A; Mozafari, M; Rostami, A; Sameni, M; Zamani, F	1
Cabot, G; Cantón, R; López-Causapé, C; Macià, MD; Moyà, B; Oliver, A; Pérez, JL; Rojo-Molinero, E; Rubio, R	1
Banerjee, R; Boyce, TG; Cunningham, SA; Hasassri, ME; Jeraldo, PR; Kaye, KS; Norgan, AP; Patel, R; Pogue, JM; Weissman, SJ	1
Bresnik, M; Clancy, JP; Derchak, PA; Flume, PA; Lewis, SA; Ramsey, BW; Retsch-Bogart, GZ; Tullis, DE	1
Bratcher, PE; Caceres, SM; Chmiel, JF; Happoldt, CL; Malcolm, KC; Nichols, DP; Nick, JA; Saavedra, MT; Saiman, L; Taylor-Cousar, JL	1
Britton, WJ; Chan, HK; Chang, RYK; Kutter, E; Lin, Y; Morales, S	1
Kaznowski, A; Konecka, E; Krzymińska, S; Mokracka, J	1
Cogen, JD; Goss, CH; Heltshe, SL; Nichols, DP; Odem-Davis, K; Ren, CL; Skalland, M; Somayaji, R	1
Kutter, JP; Moodley, A; Mu, H; Wang, J; Yang, M	1
Haines, RR; Hammer, KA; Putsathit, P; Tai, AS	1
Gu, H; Tong, K; Wei, J; Zhou, S	1
Rowbotham, NJ; Smith, S	1
Aldogan, EH; Hacioglu, M; Yilmaz, FN	1
Hernando-Amado, S; Laborda, P; López-Causapé, C; Martínez, JL; Oliver, A; Sanz-García, F	1
Cheng, ML; Duffield, J; Hu, C; Hwang, SB; Ichikawa, Y; Liang, CH; Marby, KA; Rabuka, D; Romero, A; Sears, P; Sgarbi, PW; Shue, YK; Sucheck, SJ; Yao, S	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Furuno, JP; Graffunder, E; Graves, J; Lodise, TP; Lomaestro, B; McGregor, JC; McNutt, LA; Miller, CD	1
Adams, J; de Oliveira Garcia, D; Doi, Y; Paterson, DL	1
Dumas, JL; Köhler, T; Reinhardt, A; Ricou, B; Rohner, P; van Delden, C; Wood, P	1
Correa, A; Kattan, JN; Lolans, K; Lopez, JA; Quinn, JP; Villegas, MV	1
Caniça, M; Ferreira, E; Leitão, J; Manageiro, V; Mendonça, N	1
Bonomo, RA; Endimiani, A; Hujer, AM; Hujer, KM; Luzzaro, F; Mantengoli, E; Migliavacca, R; Pagani, L; Rossolini, GM; Toniolo, A	1
Ariza, J; Dominguez, MA; Gudiol, F; Guzmán, A; Peña, C; Pujol, M; Suarez, C; Tubau, F	1
Avlami, A; Daikos, GL; Katsilambros, N; Kosmidis, C; Petrikkos, G; Psychogiou, M; Stefanou, I; Tassios, PT; Vasilakopoulou, A	1
Borrell, N; Maciá, MD; Moya, B; Oliver, A; Pérez, JL; Plasencia, V	1
Castanheira, M; Jones, RN; Mendes, RE; Sader, HS; Toleman, MA; Walsh, TR	1
Beceiro, A; Bou, G; Canle, D; Fernández, A; Lasa, I; Latasa, C; Mallo, S; Molina, F; Pérez, A; Pérez, S; Poza, M; Tomás, Mdel M; Villanueva, R	1
Bajolet, O; Berthelot, P; Bingen, E; Couetdic, G; Favre, R; Grattard, F; Hocquet, D; Husson, MO; Jeannot, K; Mariani-Kurkdjian, P; Marty, N; Plésiat, P; Roussel-Delvallez, M	1
Bouza, E; Cercenado, E; Coll, P; Gutiérrez, O; Juan, C; Navarro, F; Oliver, A; Pérez, JL	1
Bethel, CR; Bonomo, RA; Carias, LL; Endimiani, A; Fox, WR; Hall, GS; Hujer, AM; Hujer, KM; Hutton, RA; Jacobs, MR; Jenkins, SG; Paterson, DL; Perez, F; Rice, LB; Tenover, FC	1
Lombardo, F; Obach, RS; Waters, NJ	1
Attree, I; Elsen, S; Jeannot, K; Köhler, T; Plésiat, P; van Delden, C	1
Espedido, BA; Iredell, JR; Partridge, SR	1
Badur, S; Cagatay, AA; Carrër, A; Eraksoy, H; Nordmann, P; Poirel, L	1
Bauernfeind, A; Keuleyan, E; Markovska, R; Queenan, AM; Rasshofer, R; Schneider, I	1
Bratu, S; Georgescu, C; Landman, D; Martin, DA; Quale, J	1
Albertí, S; Beceiro, A; Bou, G; Garau, M; Gutiérrez, O; Juan, C; Oliver, A; Pérez, JL	1
Cattoir, V; Nordmann, P; Poirel, L	1
Baptista, BC; Correia, JD; da Fonseca, JD; Martínez-Martínez, L; Pomba, C	1
Bell, JM; Castanheira, M; Deshpande, LM; Jones, RN; Mendes, RE; Turnidge, JD	1
Bell, JM; Castanheira, M; Jones, RN; Mathai, D; Turnidge, JD	1
Juan, C; Maciá, MD; Mena, A; Mulet, X; Oliver, A; Pérez, JL	1
Duljasz, W; Gniadkowski, M; Jebelean, C; Sitter, S; Wojna, A	1
Attrée, I; Ducruix, A; El Garch, F; Llanes, C; Muller, C; Phan, G; Plésiat, P; Vettoretti, L	1
Christiansen, LE; Ciofu, O; Høiby, N; Kirkby, N; Mandsberg, LF; Poulsen, HE	1
Kirikae, T; Kitao, T; Miyoshi-Akiyama, T	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Carattoli, A; Ellington, MJ; Karisik, E; Livermore, DM; Underwood, A; Woodford, N	1
Acosta, J; Chaves, F; Juan, C; Oliver, A; Otero, JR; Sanz, F; Viedma, E; Zamorano, L	1
Albertí, S; Juan, C; Mulet, X; Oliver, A; Pérez, JL; Zamorano, L	1
Burns, JL; Dudley, MN; Griffith, DC; King, P; Lomovskaya, O	1
Courvalin, P; Coyne, S; Guigon, G; Périchon, B	1
Ge, Y; Juan, C; Oliver, A; Pérez, JL; Zamorano, L	1
Baussanne, I; Bussière, A; Décout, JL; Ennifar, E; Ganem-Elbaz, C; Halder, S; Mingeot-Leclercq, MP; Ouberai, M; Paris, JM; Riou, M	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Dunman, PM; Hood, MI; Jacobs, AC; Sayood, K; Skaar, EP	1
Beceiro, A; Bou, G; Doumith, M; Livermore, DM; Tomás, M; Turton, JF; Warner, M; Woodford, N	1
Chang, FY; Chen, TL; Fung, CP; Huang, LY; Lu, PL; Siu, LK	1
Abele-Horn, M; Claus, H; Elias, J; Engelhardt, K; Frosch, M; Joseph, B; Oesterlein, A; Schoen, C; Turnwald, D; Valenza, G	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A	1

Reviews

7 review(s) available for tobramycin and aztreonam

Article	Year
Inhaled antibiotics in cystic fibrosis: what's new? Journal of the Royal Society of Medicine, 2012, Volume: 105 Suppl 2 Topics: Administration, Inhalation; Adolescent; Amikacin; Anti-Bacterial Agents; Aztreonam; Child; Child, Preschool; Ciprofloxacin; Clinical Trials, Phase III as Topic; Cystic Fibrosis; Female; Follow-Up Studies; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Incidence; Infant; Male; Randomized Controlled Trials as Topic; Risk Assessment; Severity of Illness Index; Survival Rate; Tobramycin; Treatment Outcome	2012
A network meta-analysis of the efficacy of inhaled antibiotics for chronic Pseudomonas infections in cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2012, Volume: 11, Issue:5 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Aztreonam; Bacterial Load; Bayes Theorem; Biological Availability; Chronic Disease; Colistin; Cystic Fibrosis; Disease Progression; Female; Forced Expiratory Volume; Humans; Information Services; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Respiratory Tract Infections; Tobramycin; Treatment Outcome	2012
Inhaled antibiotics for the treatment of chronic bronchopulmonary Pseudomonas aeruginosa infection in cystic fibrosis: systematic review of randomised controlled trials. Expert opinion on pharmacotherapy, 2013, Volume: 14, Issue:9 Topics: Administration, Inhalation; Anti-Bacterial Agents; Aztreonam; Chronic Disease; Colistin; Cystic Fibrosis; Humans; Lung Diseases; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Tobramycin	2013
Inhaled antibiotics for lower airway infections. Annals of the American Thoracic Society, 2014, Volume: 11, Issue:3 Topics: Administration, Inhalation; Amikacin; Amphotericin B; Anti-Bacterial Agents; Aztreonam; Ceftazidime; Colistin; Cystic Fibrosis; Gentamicins; Humans; Nebulizers and Vaporizers; Respiratory Tract Infections; Tobramycin	2014
Aerosolized antibiotics in cystic fibrosis: an update. Expert review of respiratory medicine, 2014, Volume: 8, Issue:3 Topics: Administration, Inhalation; Amikacin; Anti-Bacterial Agents; Aztreonam; Colistin; Cystic Fibrosis; Equipment Design; Humans; Levofloxacin; Nebulizers and Vaporizers; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Tobramycin	2014
Inhaled antibiotics: dry or wet? The European respiratory journal, 2014, Volume: 44, Issue:5 Topics: Administration, Inhalation; Aerosols; Anti-Bacterial Agents; Aztreonam; Colistin; Cystic Fibrosis; Disease Progression; Dry Powder Inhalers; Humans; Nebulizers and Vaporizers; Pseudomonas aeruginosa; Tobramycin	2014
Inhaled anti-pseudomonal antibiotics for long-term therapy in cystic fibrosis. The Cochrane database of systematic reviews, 2022, Nov-14, Volume: 11 Topics: Adolescent; Adult; Anti-Bacterial Agents; Aztreonam; Child; Child, Preschool; Cystic Fibrosis; Humans; Lysine; Middle Aged; Quality of Life; Randomized Controlled Trials as Topic; Tobramycin; Young Adult	2022

Trials

15 trial(s) available for tobramycin and aztreonam

Article	Year
Sensitization to aztreonam and cross-reactivity with other beta-lactam antibiotics in high-risk patients with cystic fibrosis. The Journal of allergy and clinical immunology, 1991, Volume: 87, Issue:1 Pt 1 Topics: Adolescent; Adult; Anti-Bacterial Agents; Antibodies, Anti-Idiotypic; Azlocillin; Aztreonam; Ceftazidime; Child; Child, Preschool; Cross Reactions; Cystic Fibrosis; Drug Hypersensitivity; Female; Humans; Immunoglobulin E; Immunoglobulin G; Male; Piperacillin; Skin Tests; Ticarcillin; Tobramycin	1991
Comparison of aztreonam plus clindamycin with tobramycin plus clindamycin in the treatment of intra-abdominal infections. Chemotherapy, 1989, Volume: 35 Suppl 1 Topics: Abdomen; Adolescent; Adult; Aged; Aged, 80 and over; Aztreonam; Bacterial Infections; Clindamycin; Clinical Trials as Topic; Cross Infection; Drug Therapy, Combination; Female; Gram-Negative Bacteria; Humans; Male; Middle Aged; Random Allocation; Tobramycin	1989
A comparative analysis of aztreonam + clindamycin versus tobramycin + clindamycin or amikacin + mezlocillin in the treatment of gram-negative lower respiratory tract infections. Chemotherapy, 1989, Volume: 35 Suppl 1 Topics: Adult; Aged; Aged, 80 and over; Amikacin; Aztreonam; Bacterial Infections; Clindamycin; Clinical Trials as Topic; Cross Infection; Drug Therapy, Combination; Gram-Negative Bacteria; Humans; Male; Mezlocillin; Middle Aged; Pneumonia; Random Allocation; Tobramycin	1989
[Aztreonam versus tobramycin in acute pyelonephritis. A comparative study]. Archivos espanoles de urologia, 1989, Volume: 42, Issue:2 Topics: Acute Disease; Adult; Aged; Aztreonam; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Male; Middle Aged; Pyelonephritis; Tobramycin	1989
Controlled trial of aztreonam vs. tobramycin and azlocillin for acute pulmonary exacerbations of cystic fibrosis. The Pediatric infectious disease journal, 1988, Volume: 7, Issue:3 Topics: Adolescent; Azlocillin; Aztreonam; Child; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Liver; Male; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Random Allocation; Respiratory Tract Infections; Sputum; Tobramycin; Transaminases	1988
The effect of different measures of outcome on the results of studies of empiric antibiotic therapy in febrile neutropenic patients. Clinical and investigative medicine. Medecine clinique et experimentale, 1988, Volume: 11, Issue:5 Topics: Acute Disease; Agranulocytosis; Anti-Bacterial Agents; Aztreonam; Clinical Trials as Topic; Cloxacillin; Drug Therapy, Combination; Fever; Humans; Infection Control; Leukemia; Lymphoma; Moxalactam; Multicenter Studies as Topic; Neoplasms; Neutropenia; Prognosis; Random Allocation; Tobramycin	1988
Treatment with aztreonam or tobramycin in critical care patients with nosocomial gram-negative pneumonia. The American journal of medicine, 1985, Feb-08, Volume: 78, Issue:2A Topics: Aged; Anti-Bacterial Agents; Aztreonam; Bacterial Infections; Clinical Trials as Topic; Critical Care; Cross Infection; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Middle Aged; Pneumonia; Random Allocation; Tobramycin	1985
Efficacy and safety of aztreonam-clindamycin versus tobramycin-clindamycin in the treatment of lower respiratory tract infections caused by aerobic gram-negative bacilli. Antimicrobial agents and chemotherapy, 1985, Volume: 27, Issue:2 Topics: Aged; Anti-Bacterial Agents; Aztreonam; Bacteria, Aerobic; Clindamycin; Drug Therapy, Combination; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Respiratory Tract Infections; Tobramycin	1985
Comparison of imipenem versus cefuroxime plus tobramycin as empirical therapy for febrile granulocytopenic patients and efficacy of vancomycin and aztreonam in case of failure. Scandinavian journal of infectious diseases, 1994, Volume: 26, Issue:5 Topics: Adolescent; Adult; Aged; Agranulocytosis; Aztreonam; Cefuroxime; Drug Therapy, Combination; Female; Fever of Unknown Origin; Gram-Positive Bacterial Infections; Humans; Imipenem; Male; Microbial Sensitivity Tests; Middle Aged; Prospective Studies; Tobramycin; Treatment Failure; Vancomycin	1994
Pharmacokinetics and pharmacodynamics of aztreonam and tobramycin in hospitalized patients. Clinical therapeutics, 2001, Volume: 23, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Area Under Curve; Aztreonam; Bacterial Infections; Dose-Response Relationship, Drug; Female; Humans; Inpatients; Male; Microbial Sensitivity Tests; Middle Aged; Tobramycin; Treatment Outcome	2001
Inhaled aztreonam lysine vs. inhaled tobramycin in cystic fibrosis: a comparative efficacy trial. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2013, Volume: 12, Issue:2 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Aztreonam; Child; Cystic Fibrosis; Female; Humans; Male; Pseudomonas Infections; Respiratory Function Tests; Tobramycin; Treatment Outcome	2013
Azithromycin may antagonize inhaled tobramycin when targeting Pseudomonas aeruginosa in cystic fibrosis. Annals of the American Thoracic Society, 2014, Volume: 11, Issue:3 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Azithromycin; Aztreonam; Cystic Fibrosis; Drug Interactions; Female; Forced Expiratory Volume; Humans; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Quality of Life; Tobramycin; Young Adult	2014
Inhaled aztreonam lysine versus inhaled tobramycin in cystic fibrosis. An economic evaluation. Annals of the American Thoracic Society, 2015, Volume: 12, Issue:7 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Aztreonam; Chronic Disease; Cost-Benefit Analysis; Cystic Fibrosis; Female; Humans; Lung Transplantation; Male; Models, Economic; Pseudomonas aeruginosa; Pseudomonas Infections; Quality of Life; Tobramycin; United States; Young Adult	2015
Continuous alternating inhaled antibiotics for chronic pseudomonal infection in cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2016, Volume: 15, Issue:6 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Aztreonam; Chronic Disease; Cystic Fibrosis; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Medication Therapy Management; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Time Factors; Tobramycin; Treatment Outcome	2016
Impact of azithromycin on the clinical and antimicrobial effectiveness of tobramycin in the treatment of cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2017, Volume: 16, Issue:3 Topics: Anti-Bacterial Agents; Azithromycin; Aztreonam; Cystic Fibrosis; Drug Administration Routes; Drug Interactions; Drug Monitoring; Female; Humans; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Function Tests; Tobramycin; Treatment Outcome; Young Adult	2017

Other Studies

89 other study(ies) available for tobramycin and aztreonam

Article	Year
Synergy with aztreonam and arbekacin or tobramycin against Pseudomonas aeruginosa isolated from blood. The Journal of antimicrobial chemotherapy, 1992, Volume: 30, Issue:6 Topics: Aminoglycosides; Anti-Bacterial Agents; Aztreonam; Dibekacin; Drug Synergism; Drug Therapy, Combination; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Tobramycin	1992
[Use of aztreonam in the perioperative prevention in burned patients]. Acta bio-medica de L'Ateneo parmense : organo della Societa di medicina e scienze naturali di Parma, 1990, Volume: 61, Issue:1-2 Topics: Aztreonam; Burns; Drug Evaluation; Drug Therapy, Combination; Humans; Oxacillin; Premedication; Skin Transplantation; Tobramycin	1990
[Bacterial infections in cancer patients without neutropenia. Comparison between 2 antibiotic combinations (aztreonam and oxacillin versus cefoxitin and tobramycin)]. La Clinica terapeutica, 1989, Nov-15, Volume: 131, Issue:3 Topics: Adult; Aged; Aztreonam; Bacterial Infections; Cefoxitin; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Neoplasms; Oxacillin; Tobramycin	1989
Influence of faeces on the activity of antimicrobial agents used for decontamination of the alimentary canal. Scandinavian journal of infectious diseases, 1985, Volume: 17, Issue:3 Topics: Anti-Bacterial Agents; Aztreonam; Ciprofloxacin; Colistin; Digestive System; Dose-Response Relationship, Drug; Feces; Humans; Nalidixic Acid; Neomycin; Norfloxacin; Pipemidic Acid; Quinolines; Tobramycin	1985
Antimicrobial activity of ciprofloxacin against Pseudomonas aeruginosa, Escherichia coli, and Staphylococcus aureus determined by the killing curve method: antibiotic comparisons and synergistic interactions. Antimicrobial agents and chemotherapy, 1985, Volume: 28, Issue:2 Topics: Azlocillin; Aztreonam; Ciprofloxacin; Drug Synergism; Escherichia coli; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Quinolines; Staphylococcus aureus; Tobramycin	1985
In vitro activity of aztreonam combined with tobramycin and gentamicin against clinical isolates of Pseudomonas aeruginosa and Pseudomonas cepacia from patients with cystic fibrosis. Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:9 Topics: Aztreonam; Cystic Fibrosis; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; Gentamicins; Humans; Microbial Sensitivity Tests; Pseudomonas; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	1987
Lack of correlation between objective indicators and clinical-response scores during antimicrobial therapy for acute pulmonary exacerbations of cystic fibrosis. Clinical pharmacy, 1988, Volume: 7, Issue:12 Topics: Anti-Bacterial Agents; Azlocillin; Aztreonam; Ciprofloxacin; Cystic Fibrosis; Humans; Tobramycin	1988
The in-vitro activity and beta-lactamase stability of carumonam. The Journal of antimicrobial chemotherapy, 1986, Volume: 18, Issue:1 Topics: Anti-Bacterial Agents; Aztreonam; beta-Lactamase Inhibitors; beta-Lactamases; Cefotaxime; Ceftazidime; Culture Media; Gram-Negative Aerobic Bacteria; Microbial Sensitivity Tests; Piperacillin; Tobramycin	1986
In vitro activity against aerobic and anaerobic gram-positive and gram-negative bacteria and beta-lactamase stability of RS-533, a novel carbapenem. Antimicrobial agents and chemotherapy, 1986, Volume: 30, Issue:6 Topics: Aztreonam; beta-Lactamase Inhibitors; beta-Lactamases; Cefoperazone; Cefotaxime; Cefoxitin; Ceftazidime; Gram-Negative Bacteria; Gram-Positive Bacteria; Imipenem; Microbial Sensitivity Tests; Piperacillin; Thienamycins; Tobramycin	1986
Stability of intravenous admixtures of aztreonam and cefoxitin, gentamicin, metronidazole, or tobramycin. American journal of hospital pharmacy, 1986, Volume: 43, Issue:6 Topics: Aztreonam; Cefoxitin; Drug Combinations; Drug Stability; Drug Storage; Gentamicins; Glucose; Metronidazole; Sodium Chloride; Tobramycin	1986
Antibiotic stability in an implantable pump. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 1986, Volume: 4, Issue:4 Topics: Amikacin; Anti-Bacterial Agents; Aztreonam; Clindamycin; Drug Stability; Gentamicins; Humans; Infusion Pumps; Microbial Sensitivity Tests; Netilmicin; Osteomyelitis; Tobramycin	1986
In vitro studies of investigational beta-lactams as possible therapy for Pseudomonas aeruginosa endocarditis. Antimicrobial agents and chemotherapy, 1985, Volume: 27, Issue:1 Topics: Anti-Bacterial Agents; Aztreonam; Cefsulodin; Drug Synergism; Endocarditis, Bacterial; Humans; Imipenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Thienamycins; Ticarcillin; Tobramycin	1985
Efficacy and safety of aztreonam versus tobramycin for aerobic gram-negative bacilli lower respiratory tract infections. The American journal of medicine, 1985, Feb-08, Volume: 78, Issue:2A Topics: Anti-Bacterial Agents; Aztreonam; Bacterial Infections; Drug Administration Schedule; Drug Evaluation; Gram-Negative Aerobic Bacteria; Humans; Random Allocation; Respiratory Tract Infections; Tobramycin	1985
Binding to and antibacterial effect of aztreonam, temocillin, gentamicin and tobramycin on human faeces. The Journal of hygiene, 1985, Volume: 95, Issue:2 Topics: Aztreonam; Dose-Response Relationship, Drug; Enterobacteriaceae; Feces; Gentamicins; Humans; In Vitro Techniques; Penicillins; Tobramycin	1985
In vitro activity of carumonam. Antimicrobial agents and chemotherapy, 1985, Volume: 28, Issue:6 Topics: Anti-Bacterial Agents; Aztreonam; Clindamycin; Drug Synergism; Enterobacteriaceae; Gram-Negative Aerobic Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Nafcillin; Piperacillin; Tobramycin	1985
Comparative efficacies of piperacillin, azlocillin, ticarcillin, aztreonam, and tobramycin against experimental Pseudomonas aeruginosa pneumonia. Antimicrobial agents and chemotherapy, 1984, Volume: 25, Issue:1 Topics: Animals; Anti-Bacterial Agents; Azlocillin; Aztreonam; Guinea Pigs; Penicillins; Piperacillin; Pneumonia; Pseudomonas Infections; Ticarcillin; Tobramycin	1984
In vitro antimicrobial activity of aztreonam alone and in combination against bacterial isolates from pediatric patients. Antimicrobial agents and chemotherapy, 1984, Volume: 25, Issue:2 Topics: Anti-Bacterial Agents; Aztreonam; Bacteria; Bacterial Infections; Cefoxitin; Child; Drug Synergism; Humans; Microbial Sensitivity Tests; Time Factors; Tobramycin	1984
Comparison of the synergic activity of aztreonam or tobramycin plus piperacillin or mezlocillin. The Journal of antimicrobial chemotherapy, 1993, Volume: 32, Issue:2 Topics: Aztreonam; Drug Synergism; Drug Therapy, Combination; Humans; Mezlocillin; Microbial Sensitivity Tests; Piperacillin; Tobramycin	1993
[Antibacterial activities of combination uses of cefpirome with various antibiotics in vitro against clinically isolated glucose non-fermentative gram-negative rods: part 1. the results against Pseudomonas aeruginosa]. The Japanese journal of antibiotics, 1996, Volume: 49, Issue:1 Topics: Amikacin; Anti-Bacterial Agents; Aztreonam; Cefpirome; Cephalosporins; Drug Combinations; Drug Synergism; Gentamicins; Imipenem; Piperacillin; Pseudomonas aeruginosa; Tobramycin	1996
In vitro efficacy of levofloxacin alone or in combination tested against multi-resistant Pseudomonas aeruginosa strains. Journal of chemotherapy (Florence, Italy), 1996, Volume: 8, Issue:6 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aztreonam; Ceftazidime; Ciprofloxacin; Drug Resistance, Multiple; Gentamicins; Humans; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Piperacillin; Pseudomonas aeruginosa; Tobramycin	1996
Antimicrobial spectrum of activity for meropenem and nine broad spectrum antimicrobials: report from the MYSTIC Program (2002) in North America. Diagnostic microbiology and infectious disease, 2003, Volume: 47, Issue:1 Topics: Anti-Bacterial Agents; Aztreonam; Cefepime; Cephalosporins; Ciprofloxacin; Drug Resistance, Bacterial; Drug Resistance, Multiple; Female; Gentamicins; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Male; Meropenem; Microbial Sensitivity Tests; North America; Sensitivity and Specificity; Thienamycins; Tobramycin	2003
Inhaled antibiotics. Pediatric pulmonology. Supplement, 2004, Volume: 26 Topics: Administration, Inhalation; Anti-Bacterial Agents; Aztreonam; Chronic Disease; Cystic Fibrosis; Humans; Nebulizers and Vaporizers; Pseudomonas Infections; Tobramycin	2004
Efficacy of aerosol MP-376, a levofloxacin inhalation solution, in models of mouse lung infection due to Pseudomonas aeruginosa. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:9 Topics: Administration, Inhalation; Aerosols; Animals; Anti-Bacterial Agents; Aztreonam; Disease Models, Animal; Female; Levofloxacin; Lung Diseases; Mice; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2009
Activity of pyocin S2 against Pseudomonas aeruginosa biofilms. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:3 Topics: Animals; Anti-Bacterial Agents; Aztreonam; Biofilms; Child; Cystic Fibrosis; Humans; Larva; Lung; Microscopy, Electron, Scanning; Moths; Pseudomonas aeruginosa; Pyocins; Sputum; Tobramycin	2012
Therapeutic approaches to chronic cystic fibrosis respiratory infections with available, emerging aerosolized antibiotics. Respiratory medicine, 2011, Volume: 105 Suppl 2 Topics: Administration, Inhalation; Aerosols; Anti-Bacterial Agents; Aztreonam; Chronic Disease; Cystic Fibrosis; Female; Forced Expiratory Volume; Humans; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Respiratory Tract Infections; Tobramycin; Treatment Outcome	2011
In vitro evaluation of tobramycin and aztreonam versus Pseudomonas aeruginosa biofilms on cystic fibrosis-derived human airway epithelial cells. The Journal of antimicrobial chemotherapy, 2012, Volume: 67, Issue:11 Topics: Anti-Bacterial Agents; Aztreonam; Biofilms; Cystic Fibrosis; Epithelial Cells; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Time Factors; Tobramycin	2012
Aztreonam for inhalation solution, challenges to drug approval and integration into CF care. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2013, Volume: 12, Issue:2 Topics: Anti-Bacterial Agents; Aztreonam; Cystic Fibrosis; Female; Humans; Male; Pseudomonas Infections; Tobramycin	2013
Combination of hypothiocyanite and lactoferrin (ALX-109) enhances the ability of tobramycin and aztreonam to eliminate Pseudomonas aeruginosa biofilms growing on cystic fibrosis airway epithelial cells. The Journal of antimicrobial chemotherapy, 2015, Volume: 70, Issue:1 Topics: Anti-Bacterial Agents; Aztreonam; Biofilms; Cells, Cultured; Colony Count, Microbial; Drug Combinations; Drug Synergism; Epithelial Cells; Humans; Lactoferrin; Microbial Viability; Pseudomonas aeruginosa; Thiocyanates; Tobramycin	2015
Association between the introduction of a new cystic fibrosis inhaled antibiotic class and change in prevalence of patients receiving multiple inhaled antibiotic classes. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2015, Volume: 14, Issue:3 Topics: Administration, Inhalation; Adolescent; Adult; Aerosols; Anti-Bacterial Agents; Aztreonam; Child; Colistin; Cystic Fibrosis; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Prevalence; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Tobramycin; Treatment Outcome; Young Adult	2015
Effect of High-Dose Antimicrobials on Biofilm Growth of Achromobacter Species Isolated from Cystic Fibrosis Patients. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:1 Topics: Achromobacter; Amikacin; Anti-Bacterial Agents; Aztreonam; Biofilms; Colistin; Cystic Fibrosis; Gram-Negative Bacterial Infections; Humans; Levofloxacin; Microbial Sensitivity Tests; Plankton; Tobramycin	2016
Silver- and fluoride-containing mesoporous bioactive glasses versus commonly used antibiotics: Activity against multidrug-resistant bacterial strains isolated from patients with burns. Burns : journal of the International Society for Burn Injuries, 2016, Volume: 42, Issue:1 Topics: Amikacin; Animals; Anti-Bacterial Agents; Aztreonam; Burns; Carbenicillin; Cefepime; Ceftazidime; Ceftriaxone; Cell Survival; Cephalosporins; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Fluorides; Gentamicins; Glass; Humans; Imipenem; Meropenem; Mice; Microbial Sensitivity Tests; NIH 3T3 Cells; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Silver; Thienamycins; Tobramycin; Wound Infection	2016
Sequential Treatment of Biofilms with Aztreonam and Tobramycin Is a Novel Strategy for Combating Pseudomonas aeruginosa Chronic Respiratory Infections. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:5 Topics: Anti-Bacterial Agents; Aztreonam; Biofilms; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin	2016
An Immunocompromised Child with Bloodstream Infection Caused by Two Escherichia coli Strains, One Harboring NDM-5 and the Other Harboring OXA-48-Like Carbapenemase. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:6 Topics: Adolescent; Amikacin; Anti-Bacterial Agents; Aztreonam; Bacterial Proteins; beta-Lactamases; beta-Lactams; Ciprofloxacin; Ertapenem; Escherichia coli; Female; Gentamicins; Humans; Immunocompromised Host; Meropenem; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tazobactam; Thienamycins; Tobramycin	2016
Synergy of nebulized phage PEV20 and ciprofloxacin combination against Pseudomonas aeruginosa. International journal of pharmaceutics, 2018, Nov-15, Volume: 551, Issue:1-2 Topics: Amikacin; Anti-Bacterial Agents; Aztreonam; Ciprofloxacin; Colistin; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Phages; Tobramycin	2018
Evaluation of The Pathogenic Potential of Insecticidal Polish journal of microbiology, 2019, Volume: 68, Issue:2 Topics: Animals; Anti-Bacterial Agents; Aztreonam; Biological Control Agents; Cefepime; Chlorocebus aethiops; Enterobactin; Gentamicins; Humans; Insecticides; Microbial Sensitivity Tests; Serratia marcescens; Spodoptera; Sulfamethoxazole; Tobramycin; Vero Cells	2019
Pulmonary Outcomes Associated with Long-Term Azithromycin Therapy in Cystic Fibrosis. American journal of respiratory and critical care medicine, 2020, 02-15, Volume: 201, Issue:4 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Azithromycin; Aztreonam; Child; Cohort Studies; Cystic Fibrosis; Female; Humans; Male; Pseudomonas aeruginosa; Retrospective Studies; Tobramycin; Young Adult	2020
Synergistic antibacterial effect of inhaled aztreonam and tobramycin fixed dose combination to combat multidrug-resistant Gram-negative bacteria. International journal of pharmaceutics, 2020, Nov-30, Volume: 590 Topics: Administration, Inhalation; Aerosols; Anti-Bacterial Agents; Anti-Infective Agents; Aztreonam; Dry Powder Inhalers; Particle Size; Powders; Pseudomonas aeruginosa; Tobramycin	2020
Antimicrobial effects of Melaleuca alternifolia (tea tree) essential oil against biofilm-forming multidrug-resistant cystic fibrosis-associated Pseudomonas aeruginosa as a single agent and in combination with commonly nebulized antibiotics. Letters in applied microbiology, 2022, Volume: 75, Issue:3 Topics: Anti-Bacterial Agents; Aztreonam; Biofilms; Colistin; Cystic Fibrosis; Melaleuca; Microbial Sensitivity Tests; Oils, Volatile; Pseudomonas aeruginosa; Tea; Tea Tree Oil; Tobramycin; Trees	2022
Meropenem-loaded Cement Is Effective in Preventing Gram-negative Osteomyelitis in an Animal Model. Clinical orthopaedics and related research, 2023, 01-01, Volume: 481, Issue:1 Topics: Animals; Anti-Bacterial Agents; Aztreonam; Bone Cements; Ceftazidime; Ciprofloxacin; Escherichia coli; Male; Meropenem; Microbial Sensitivity Tests; Models, Animal; Osteomyelitis; Piperacillin; Rats; Tobramycin	2023
Impact of N-Acetylcysteine and Antibiotics Against Single and Dual Species Biofilms of Pseudomonas aeruginosa and Achromobacter xylosoxidans. Current microbiology, 2022, Nov-25, Volume: 80, Issue:1 Topics: Acetylcysteine; Achromobacter denitrificans; Animals; Anti-Bacterial Agents; Aztreonam; Biofilms; Caenorhabditis elegans; Ciprofloxacin; Cystic Fibrosis; Humans; Pseudomonas aeruginosa; Tobramycin	2022
Rapid Phenotypic Convergence towards Collateral Sensitivity in Clinical Isolates of Pseudomonas aeruginosa Presenting Different Genomic Backgrounds. Microbiology spectrum, 2023, 02-14, Volume: 11, Issue:1 Topics: Anti-Bacterial Agents; Aztreonam; Ciprofloxacin; Drug Collateral Sensitivity; Genomics; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2023
Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. Bioorganic & medicinal chemistry letters, 2005, Apr-15, Volume: 15, Issue:8 Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Drug Evaluation, Preclinical; Female; Humans; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Structure-Activity Relationship	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Clinical prediction tool to identify patients with Pseudomonas aeruginosa respiratory tract infections at greatest risk for multidrug resistance. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:2 Topics: Adult; Anti-Bacterial Agents; Case-Control Studies; Drug Resistance, Multiple, Bacterial; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Predictive Value of Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Retrospective Studies; Risk; Risk Factors	2007
Coproduction of novel 16S rRNA methylase RmtD and metallo-beta-lactamase SPM-1 in a panresistant Pseudomonas aeruginosa isolate from Brazil. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:3 Topics: Amino Acid Sequence; Aminoglycosides; beta-Lactamases; Brazil; Carbapenems; Cloning, Molecular; Drug Resistance, Multiple, Bacterial; Methyltransferases; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Pseudomonas aeruginosa; Pseudomonas Infections	2007
Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4 Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Drug Resistance, Bacterial; Humans; Longitudinal Studies; Pneumonia, Ventilator-Associated; Polymerase Chain Reaction; Pseudomonas aeruginosa; Pseudomonas Infections	2007
First identification of Pseudomonas aeruginosa isolates producing a KPC-type carbapenem-hydrolyzing beta-lactamase. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4 Topics: beta-Lactamases; Carbapenems; Drug Resistance, Bacterial; Hydrolysis; Microbial Sensitivity Tests; Pseudomonas aeruginosa	2007
Spread of extended-spectrum beta-lactamase CTX-M-producing escherichia coli clinical isolates in community and nosocomial environments in Portugal. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6 Topics: Aged; Anti-Bacterial Agents; beta-Lactamases; Community-Acquired Infections; Cross Infection; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Humans; Microbial Sensitivity Tests; Middle Aged; Portugal	2007
Spread in an Italian hospital of a clonal Acinetobacter baumannii strain producing the TEM-92 extended-spectrum beta-lactamase. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6 Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Cross Infection; Humans; Italy; Microbial Sensitivity Tests	2007
Effects of carbapenem exposure on the risk for digestive tract carriage of intensive care unit-endemic carbapenem-resistant Pseudomonas aeruginosa strains in critically ill patients. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6 Topics: Adult; Aged; Anti-Bacterial Agents; beta-Lactam Resistance; Carbapenems; Carrier State; Critical Illness; Endemic Diseases; Female; Gastrointestinal Tract; Humans; Imipenem; Incidence; Intensive Care Units; Male; Middle Aged; Pharynx; Pseudomonas aeruginosa; Pseudomonas Infections; Rectum; Risk Factors	2007
Enterobacteriaceae bloodstream infections: presence of integrons, risk factors, and outcome. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7 Topics: Bacteremia; Community-Acquired Infections; Cross Infection; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Enterobacteriaceae Infections; Gene Transfer, Horizontal; Humans; Infectious Disease Transmission, Professional-to-Patient; Integrons; Microbial Sensitivity Tests; Nucleic Acid Amplification Techniques; Polymerase Chain Reaction; Prospective Studies; Risk Factors; Sequence Analysis, DNA; Treatment Outcome	2007
Influence of high mutation rates on the mechanisms and dynamics of in vitro and in vivo resistance development to single or combined antipseudomonal agents. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7 Topics: Animals; Anti-Bacterial Agents; Ceftazidime; Ciprofloxacin; Disease Models, Animal; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; Female; Humans; In Vitro Techniques; Lung; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Mutation; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2007
Characterization of an integron carrying blaIMP-1 and a new aminoglycoside resistance gene, aac(6')-31, and its dissemination among genetically unrelated clinical isolates in a Brazilian hospital. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7 Topics: Acinetobacter; Amino Acid Sequence; Aminoglycosides; Anti-Bacterial Agents; Base Sequence; Brazil; Codon, Terminator; Cross Infection; Drug Resistance, Multiple, Bacterial; Gene Transfer, Horizontal; Genes, Bacterial; Hospitals; Humans; Integrons; Microbial Sensitivity Tests; Molecular Sequence Data; Open Reading Frames; Plasmids; Pseudomonas putida; Transcription, Genetic	2007
Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:9 Topics: Bacterial Proteins; Base Sequence; beta-Lactamases; Carrier Proteins; Cloning, Molecular; DNA, Bacterial; Drug Resistance, Bacterial; Enterobacter cloacae; Enterobacteriaceae Infections; Genes, MDR; Genetic Vectors; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Porins	2007
Pseudomonas aeruginosa may accumulate drug resistance mechanisms without losing its ability to cause bloodstream infections. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:10 Topics: Aminoglycosides; Anti-Bacterial Agents; Bacteremia; beta-Lactams; DNA, Bacterial; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Fluoroquinolones; Genotype; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Reverse Transcriptase Polymerase Chain Reaction	2007
Molecular epidemiology and mechanisms of carbapenem resistance in Pseudomonas aeruginosa isolates from Spanish hospitals. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12 Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Carbapenems; Chromosomes, Bacterial; Cross Infection; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Integrons; Molecular Epidemiology; Molecular Sequence Data; Mutation; Plasmids; Polymerase Chain Reaction; Porins; Pseudomonas aeruginosa; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Spain	2007
Presence of plasmid-mediated quinolone resistance in Klebsiella pneumoniae isolates possessing blaKPC in the United States. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:7 Topics: Aged; Bacterial Proteins; Base Sequence; beta-Lactamases; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Genes, Bacterial; Humans; Klebsiella Infections; Klebsiella pneumoniae; Male; Microbial Sensitivity Tests; Molecular Epidemiology; Plasmids; Quinolones; United States	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Resistance and virulence of Pseudomonas aeruginosa clinical strains overproducing the MexCD-OprJ efflux pump. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:7 Topics: Adult; Aged; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; Ciprofloxacin; DNA Primers; DNA-Binding Proteins; DNA, Bacterial; Drug Resistance, Bacterial; Female; Genes, Bacterial; Humans; Male; Membrane Proteins; Membrane Transport Proteins; Middle Aged; Molecular Sequence Data; Mutation; Pseudomonas aeruginosa; Pseudomonas Infections; Transcription Factors; Virulence	2008
bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8 Topics: Australia; Bacterial Proteins; beta-Lactamases; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Molecular Sequence Data; Polymerase Chain Reaction; Sequence Analysis, DNA	2008
Spread of OXA-48-positive carbapenem-resistant Klebsiella pneumoniae isolates in Istanbul, Turkey. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8 Topics: Bacterial Proteins; beta-Lactamases; Carbapenems; Cross Infection; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Models, Genetic; Turkey	2008
VIM-15 and VIM-16, two new VIM-2-like metallo-beta-lactamases in Pseudomonas aeruginosa isolates from Bulgaria and Germany. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8 Topics: Amino Acid Substitution; Bacterial Proteins; beta-Lactamases; Bulgaria; Catalysis; Germany; Hydrolysis; Isoenzymes; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Pseudomonas aeruginosa; Sequence Analysis, DNA	2008
Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:9 Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; beta-Lactamases; Drug Resistance, Bacterial; Endemic Diseases; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; New York City; Sequence Analysis, DNA	2008
Characterization of the new metallo-beta-lactamase VIM-13 and its integron-borne gene from a Pseudomonas aeruginosa clinical isolate in Spain. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:10 Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; beta-Lactam Resistance; beta-Lactamases; Cloning, Molecular; DNA Primers; DNA, Bacterial; Genes, Bacterial; Genetic Variation; Humans; Imipenem; Integrons; Kinetics; Meropenem; Molecular Sequence Data; Phylogeny; Pseudomonas aeruginosa; Pseudomonas Infections; Recombinant Proteins; Sequence Homology, Amino Acid; Spain; Thienamycins	2008
Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:10 Topics: Aged; Base Sequence; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Female; Fluoroquinolones; France; Genes, Bacterial; Humans; Models, Genetic; Molecular Sequence Data; Plasmids	2008
Detection of the pandemic O25-ST131 human virulent Escherichia coli CTX-M-15-producing clone harboring the qnrB2 and aac(6')-Ib-cr genes in a dog. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:1 Topics: Animals; Anti-Bacterial Agents; Dogs; Drug Resistance, Bacterial; Escherichia coli; Genes, Bacterial; Humans; Plasmids; Virulence	2009
Codetection of blaOXA-23-like gene (blaOXA-133) and blaOXA-58 in Acinetobacter radioresistens: report from the SENTRY antimicrobial surveillance program. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:2 Topics: Acinetobacter; Anti-Bacterial Agents; beta-Lactamases; Drug Resistance, Bacterial; Molecular Sequence Data; Plasmids; Population Surveillance; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic	2009
Carbapenem resistance among Pseudomonas aeruginosa strains from India: evidence for nationwide endemicity of multiple metallo-beta-lactamase clones (VIM-2, -5, -6, and -11 and the newly characterized VIM-18). Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:3 Topics: Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; beta-Lactamases; Carbapenems; Drug Resistance, Bacterial; Humans; India; Microbial Sensitivity Tests; Molecular Sequence Data; Prevalence; Pseudomonas aeruginosa; Ribotyping	2009
Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:4 Topics: Anti-Bacterial Agents; Azithromycin; Bacterial Proteins; Biofilms; Cefepime; Cephalosporins; Ciprofloxacin; Cystic Fibrosis; DNA-Binding Proteins; Humans; Membrane Proteins; Membrane Transport Proteins; Microbial Sensitivity Tests; Mutation; MutS DNA Mismatch-Binding Protein; Pseudomonas aeruginosa; Transcription Factors	2009
First organisms with acquired metallo-beta-lactamases (IMP-13, IMP-22, and VIM-2) reported in Austria. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:5 Topics: Austria; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Pseudomonas aeruginosa; Pseudomonas Infections; Sequence Analysis, DNA	2009
Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:5 Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; beta-Lactams; Cystic Fibrosis; Gene Expression Regulation, Bacterial; Humans; Membrane Transport Proteins; Microbial Sensitivity Tests; Mutation; Pseudomonas aeruginosa; Pseudomonas Infections; Sputum	2009
Antibiotic resistance in Pseudomonas aeruginosa strains with increased mutation frequency due to inactivation of the DNA oxidative repair system. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:6 Topics: Cystic Fibrosis; DNA Repair; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Mutation; Neutrophil Activation; Oxidation-Reduction; Oxidative Stress; Pseudomonas aeruginosa	2009
AAC(6')-Iaf, a novel aminoglycoside 6'-N-acetyltransferase from multidrug-resistant Pseudomonas aeruginosa clinical isolates. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:6 Topics: Acetylation; Acetyltransferases; Aminoglycosides; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Integrons; Microbial Sensitivity Tests; Pseudomonas aeruginosa	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Complete nucleotide sequences of plasmids pEK204, pEK499, and pEK516, encoding CTX-M enzymes in three major Escherichia coli lineages from the United Kingdom, all belonging to the international O25:H4-ST131 clone. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:10 Topics: beta-Lactamases; Computational Biology; Escherichia coli; Models, Genetic; Molecular Sequence Data; Open Reading Frames; Plasmids; United Kingdom	2009
Nosocomial spread of colistin-only-sensitive sequence type 235 Pseudomonas aeruginosa isolates producing the extended-spectrum beta-lactamases GES-1 and GES-5 in Spain. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:11 Topics: Anti-Bacterial Agents; Base Sequence; beta-Lactamases; Colistin; Cross Infection; Humans; Molecular Sequence Data; Pseudomonas aeruginosa	2009
Detection of the novel extended-spectrum beta-lactamase OXA-161 from a plasmid-located integron in Pseudomonas aeruginosa clinical isolates from Spain. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:12 Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Clavulanic Acid; Gentamicins; Humans; Imipenem; Integrons; Meropenem; Molecular Sequence Data; Penicillanic Acid; Piperacillin; Plasmids; Pseudomonas aeruginosa; Pseudomonas Infections; Spain; Tazobactam; Thienamycins	2009
In vitro pharmacodynamics of levofloxacin and other aerosolized antibiotics under multiple conditions relevant to chronic pulmonary infection in cystic fibrosis. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1 Topics: Aerosols; Anti-Bacterial Agents; Bacteria; Biofilms; Chronic Disease; Ciprofloxacin; Colony Count, Microbial; Cystic Fibrosis; Humans; Levofloxacin; Lung Diseases; Microbial Sensitivity Tests; Ofloxacin; Sputum	2010
Screening and quantification of the expression of antibiotic resistance genes in Acinetobacter baumannii with a microarray. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1 Topics: Acinetobacter baumannii; Anti-Bacterial Agents; DNA, Bacterial; DNA, Complementary; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Genes, MDR; Metals, Heavy; Microbial Sensitivity Tests; Mutation; Oligonucleotide Array Sequence Analysis; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; RNA, Bacterial	2010
Activity of a new antipseudomonal cephalosporin, CXA-101 (FR264205), against carbapenem-resistant and multidrug-resistant Pseudomonas aeruginosa clinical strains. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:2 Topics: Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Cephalosporins; Drug Resistance, Multiple, Bacterial; Humans; Isoelectric Focusing; Microbial Sensitivity Tests; Polymerase Chain Reaction; Pseudomonas aeruginosa; Pseudomonas Infections	2010
Synthesis and antimicrobial evaluation of amphiphilic neamine derivatives. Journal of medicinal chemistry, 2010, Jan-14, Volume: 53, Issue:1 Topics: Anti-Bacterial Agents; Calorimetry; Framycetin; Gram-Negative Bacteria; Microbial Sensitivity Tests; Molecular Structure; Staphylococcus aureus; Stereoisomerism; Structure-Activity Relationship	2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Acinetobacter baumannii increases tolerance to antibiotics in response to monovalent cations. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:3 Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Proteins; Cations, Monovalent; Culture Media; Drug Resistance, Bacterial; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Humans; Microbial Sensitivity Tests; Oligonucleotide Array Sequence Analysis; Proteomics; Sodium Chloride; Virulence Factors	2010
Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5 Topics: Bacterial Outer Membrane Proteins; Bacterial Proteins; beta-Lactamases; Cystic Fibrosis; Drug Resistance, Bacterial; Drug Resistance, Multiple; Electrophoresis, Gel, Pulsed-Field; Humans; Membrane Transport Proteins; Mutation; Porins; Pseudomonas aeruginosa; Pseudomonas Infections; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation	2010
Molecular characterization of beta-lactamase genes and their genetic structures in Acinetobacter genospecies 3 isolates in Taiwan. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:6 Topics: Acinetobacter; Acinetobacter Infections; beta-Lactam Resistance; beta-Lactamases; Cephalosporinase; Gene Transfer, Horizontal; Genes, Bacterial; Humans; In Vitro Techniques; Integrons; Microbial Sensitivity Tests; Molecular Epidemiology; Molecular Sequence Data; Phylogeny; Taiwan	2010
First survey of metallo-beta-lactamases in clinical isolates of Pseudomonas aeruginosa in a German university hospital. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:8 Topics: Anti-Bacterial Agents; beta-Lactamases; Ceftazidime; Drug Resistance, Bacterial; Germany; Hospitals, University; Humans; Imipenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR. European journal of medicinal chemistry, 2011, Volume: 46, Issue:1 Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics	2011