tipifarnib has been researched along with tanespimycin in 3 studies
| Studies (tipifarnib) | Trials (tipifarnib) | Recent Studies (post-2010) (tipifarnib) | Studies (tanespimycin) | Trials (tanespimycin) | Recent Studies (post-2010) (tanespimycin) |
|---|---|---|---|---|---|
| 309 | 92 | 94 | 921 | 39 | 496 |
| Protein | Taxonomy | tipifarnib (IC50) | tanespimycin (IC50) |
|---|---|---|---|
| Corticotropin releasing hormone receptor 2 | Sus scrofa (pig) | 0.004 | |
| Lysine-specific demethylase 6B | Homo sapiens (human) | 0.4 | |
| Lysine-specific demethylase 4B | Homo sapiens (human) | 0.7 | |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | 3 | |
| ATP-dependent molecular chaperone HSP82 | Saccharomyces cerevisiae S288C | 7.65 | |
| Receptor tyrosine-protein kinase erbB-2 | Homo sapiens (human) | 0.031 | |
| Heat shock protein HSP 90-alpha | Homo sapiens (human) | 0.9391 | |
| Heat shock protein HSP 90-beta | Homo sapiens (human) | 0.5124 | |
| Breakpoint cluster region protein | Homo sapiens (human) | 3 | |
| Lysine-specific demethylase 5A | Homo sapiens (human) | 0.13 | |
| Endoplasmin | Canis lupus familiaris (dog) | 0.031 | |
| Heat shock protein 75 kDa, mitochondrial | Homo sapiens (human) | 1.496 | |
| Putative heat shock protein HSP 90-alpha A4 | Homo sapiens (human) | 0.78 | |
| Lysine-specific demethylase 4C | Homo sapiens (human) | 0.7 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beloueche, M; Jackson, LE; Leach, MO; Ronen, SM | 1 |
| Bentke, A; Krzykowska-Petitjean, K; Laidler, P; Małecki, J; Ostrowska, B | 2 |
3 other study(ies) available for tipifarnib and tanespimycin
| Article | Year |
|---|---|
Magnetic resonance detects changes in phosphocholine associated with Ras activation and inhibition in NIH 3T3 cells.
Topics: 3T3 Cells; Animals; Benzoquinones; Biomarkers, Tumor; Cell Division; Cell Line, Transformed; Enzyme Inhibitors; Genes, ras; Lactams, Macrocyclic; Magnetic Resonance Spectroscopy; MAP Kinase Signaling System; Mice; Mutation; Nucleotides; Phosphorylcholine; Proto-Oncogene Proteins p21(ras); Quinolones; Rifabutin; Simvastatin; Transfection | 2001 |
Tipifarnib and tanespimycin show synergic proapoptotic activity in U937 cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzoquinones; Blotting, Western; Caspase 3; Drug Synergism; HSP90 Heat-Shock Proteins; Humans; In Situ Nick-End Labeling; Lactams, Macrocyclic; Protein Serine-Threonine Kinases; Quinolones; U937 Cells | 2012 |
Tanespimycin and tipifarnib exhibit synergism in inducing apoptosis in melanoma cell lines from later stages of tumor progression.
Topics: Antineoplastic Agents; Apoptosis; Benzoquinones; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Activation; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Melanoma; Protein Serine-Threonine Kinases; Quinolones | 2013 |