Page last updated: 2024-09-04

tipifarnib and pd 184352

tipifarnib has been researched along with pd 184352 in 2 studies

Compound Research Comparison

Studies (tipifarnib)	Trials (tipifarnib)	Recent Studies (post-2010) (tipifarnib)	Studies (pd 184352)	Trials (pd 184352)	Recent Studies (post-2010) (pd 184352)
309	92	94	185	3	74

Protein Interaction Comparison

Protein	Taxonomy	pd 184352 (IC50)
RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)	0.012
Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)	0.0263
Casein kinase II subunit alpha	Homo sapiens (human)	0.017
Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)	0.0218

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ	1
Dancey, JE	1

Reviews

1 review(s) available for tipifarnib and pd 184352

Article	Year
Agents targeting ras signaling pathway. Current pharmaceutical design, 2002, Volume: 8, Issue:25 Topics: Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Benzamides; Benzodiazepines; Enzyme Inhibitors; Farnesyltranstransferase; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Imidazoles; MAP Kinase Kinase Kinases; Oligonucleotides, Antisense; Phosphorothioate Oligonucleotides; Piperidines; Proto-Oncogene Proteins c-raf; Pyridines; Quinolones; Signal Transduction	2002

Article

Year

Agents targeting ras signaling pathway.

Current pharmaceutical design, 2002, Volume: 8, Issue:25

Topics: Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Benzamides; Benzodiazepines; Enzyme Inhibitors; Farnesyltranstransferase; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Imidazoles; MAP Kinase Kinase Kinases; Oligonucleotides, Antisense; Phosphorothioate Oligonucleotides; Piperidines; Proto-Oncogene Proteins c-raf; Pyridines; Quinolones; Signal Transduction

2002

Other Studies

1 other study(ies) available for tipifarnib and pd 184352

Article	Year
Identification of potent Yes1 kinase inhibitors using a library screening approach. Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15 Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship	2013

Article

Year

Identification of potent Yes1 kinase inhibitors using a library screening approach.

Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013