tipifarnib has been researched along with ggti 298 in 2 studies
| Studies (tipifarnib) | Trials (tipifarnib) | Recent Studies (post-2010) (tipifarnib) | Studies (ggti 298) | Trials (ggti 298) | Recent Studies (post-2010) (ggti 298) |
|---|---|---|---|---|---|
| 309 | 92 | 94 | 71 | 0 | 17 |
| Protein | Taxonomy | tipifarnib (IC50) | ggti 298 (IC50) |
|---|---|---|---|
| Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | Homo sapiens (human) | 0.054 | |
| Geranylgeranyl transferase type-1 subunit beta | Homo sapiens (human) | 0.054 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bell, IM | 1 |
| Abbruzzese, A; Caraglia, M; D'Alessandro, A; Giuberti, G; Iannuzzi, C; Irace, G; Misso, G; Sirangelo, I; Vilasi, S | 1 |
1 review(s) available for tipifarnib and ggti 298
| Article | Year |
|---|---|
Inhibitors of farnesyltransferase: a rational approach to cancer chemotherapy?
Topics: Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Drug Design; Farnesyltranstransferase; Genes, ras; Humans; Neoplasms | 2004 |
1 other study(ies) available for tipifarnib and ggti 298
| Article | Year |
|---|---|
W7FW14F apomyoglobin amyloid aggregates-mediated apoptosis is due to oxidative stress and AKT inactivation caused by Ras and Rac.
Topics: Amyloid; Animals; Apoproteins; Apoptosis; Benzamides; Cell Line; Cell Survival; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Humans; Mice; Microscopy, Fluorescence; Mitochondria; Models, Biological; Mutant Proteins; Myoglobin; Oxidative Stress; Protein Structure, Quaternary; Proto-Oncogene Proteins c-akt; Quinolones; rac GTP-Binding Proteins; ras Proteins | 2009 |