Page last updated: 2024-09-04

tipifarnib and ggti 298

tipifarnib has been researched along with ggti 298 in 2 studies

Compound Research Comparison

Studies
(tipifarnib)
Trials
(tipifarnib)
Recent Studies (post-2010)
(tipifarnib)
Studies
(ggti 298)
Trials
(ggti 298)
Recent Studies (post-2010) (ggti 298)
309929471017

Protein Interaction Comparison

ProteinTaxonomytipifarnib (IC50)ggti 298 (IC50)
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alphaHomo sapiens (human)0.054
Geranylgeranyl transferase type-1 subunit betaHomo sapiens (human)0.054

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bell, IM1
Abbruzzese, A; Caraglia, M; D'Alessandro, A; Giuberti, G; Iannuzzi, C; Irace, G; Misso, G; Sirangelo, I; Vilasi, S1

Reviews

1 review(s) available for tipifarnib and ggti 298

ArticleYear
Inhibitors of farnesyltransferase: a rational approach to cancer chemotherapy?
    Journal of medicinal chemistry, 2004, Apr-08, Volume: 47, Issue:8

    Topics: Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Drug Design; Farnesyltranstransferase; Genes, ras; Humans; Neoplasms

2004

Other Studies

1 other study(ies) available for tipifarnib and ggti 298

ArticleYear
W7FW14F apomyoglobin amyloid aggregates-mediated apoptosis is due to oxidative stress and AKT inactivation caused by Ras and Rac.
    Journal of cellular physiology, 2009, Volume: 221, Issue:2

    Topics: Amyloid; Animals; Apoproteins; Apoptosis; Benzamides; Cell Line; Cell Survival; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Humans; Mice; Microscopy, Fluorescence; Mitochondria; Models, Biological; Mutant Proteins; Myoglobin; Oxidative Stress; Protein Structure, Quaternary; Proto-Oncogene Proteins c-akt; Quinolones; rac GTP-Binding Proteins; ras Proteins

2009