Page last updated: 2024-09-04

tipifarnib and clofarabine

tipifarnib has been researched along with clofarabine in 4 studies

Compound Research Comparison

Studies
(tipifarnib)
Trials
(tipifarnib)
Recent Studies (post-2010)
(tipifarnib)
Studies
(clofarabine)
Trials
(clofarabine)
Recent Studies (post-2010) (clofarabine)
3099294424101280

Protein Interaction Comparison

ProteinTaxonomytipifarnib (IC50)clofarabine (IC50)
cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)3.12

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gore, SD1
Steensma, DP1
Baer, MR; Gojo, I1
Burnett, AK; Hills, RK1

Reviews

1 review(s) available for tipifarnib and clofarabine

ArticleYear
Novel therapies for myelodysplastic syndromes.
    Hematology/oncology clinics of North America, 2010, Volume: 24, Issue:2

    Topics: Adenine Nucleotides; Aged; Alkylating Agents; Antimetabolites; Arabinonucleosides; Clinical Trials as Topic; Clofarabine; DNA Repair; Drug Therapy, Combination; Drugs, Investigational; Enzyme Activation; Enzyme Inhibitors; Farnesyltranstransferase; Glutathione; Histone Deacetylase Inhibitors; Humans; Hydrazines; JNK Mitogen-Activated Protein Kinases; Myelodysplastic Syndromes; Quinolones; Sulfonamides; Therapies, Investigational

2010

Other Studies

3 other study(ies) available for tipifarnib and clofarabine

ArticleYear
New agents for the treatment of AML recent study findings.
    Clinical advances in hematology & oncology : H&O, 2008, Volume: 6, Issue:11

    Topics: Adenine Nucleotides; Antineoplastic Agents; Arabinonucleosides; Azacitidine; Carbazoles; Clofarabine; Decitabine; Enzyme Inhibitors; Furans; Humans; Hydrazines; Immunotherapy; Lenalidomide; Leukemia, Myeloid, Acute; Quinolones; Staurosporine; Sulfonamides; Thalidomide

2008
Novel agents for the treatment of acute myeloid leukemia in the older patient.
    Journal of the National Comprehensive Cancer Network : JNCCN, 2011, Volume: 9, Issue:3

    Topics: Adenine Nucleotides; Age Factors; Aged; Antineoplastic Agents; Arabinonucleosides; Azacitidine; Clofarabine; Cytosine; Decitabine; Disease-Free Survival; Hematopoietic Stem Cell Transplantation; Humans; Lenalidomide; Leukemia, Myeloid, Acute; Middle Aged; Prognosis; Quinolones; Thalidomide

2011
Applicability of a "Pick a Winner" trial design to acute myeloid leukemia.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Adenine Nucleotides; Aged; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Arsenic Trioxide; Arsenicals; Clinical Trials, Phase III as Topic; Clofarabine; Cost-Benefit Analysis; Cytarabine; Cytosine; Drug Discovery; Early Termination of Clinical Trials; Follow-Up Studies; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Middle Aged; Multicenter Studies as Topic; Oxides; Patient Selection; Quality-Adjusted Life Years; Quinolones; Randomized Controlled Trials as Topic; Research Design; Sample Size; Software Design; Treatment Outcome; United Kingdom

2011