tipepidine has been researched along with piperidines in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (8.00) | 18.7374 |
| 1990's | 2 (8.00) | 18.2507 |
| 2000's | 2 (8.00) | 29.6817 |
| 2010's | 15 (60.00) | 24.3611 |
| 2020's | 4 (16.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kamikawa, Y; Shimo, Y | 1 |
| Fujii, Y; Iwaki, M; Ogiso, T; Tanino, T; Yamashita, K | 1 |
| Cuomo, RM | 1 |
| Baggio, P; Danda, R; Fumiani, G | 1 |
| Kobayashi, M; Koida, Y; Matsubara, K; Sugimoto, M | 1 |
| Honda, S; Inoue, M; Kawaura, K; Ogata, Y; Shirasaki, T; Soeda, F; Takahama, K | 1 |
| Honda, S; Kawaura, K; Shirasaki, T; Soeda, F; Takahama, K | 2 |
| Itoh, M; Iwabuchi, C; Kanto, H; Ohashi, N | 1 |
| Honda, S; Kawaura, K; Miki, R; Shehata, AM; Shirasaki, T; Soeda, F; Takahama, K; Urashima, Y | 1 |
| Arakawa, C; Endo, A; Fuchigami, T; Fujita, Y; Imai, Y; Ishii, W; Kohira, R; Mugishima, H | 1 |
| Kawahara, R; Kawaura, K; Miki, R; Shirasaki, T; Soeda, F; Takahama, K; Urashima, Y | 1 |
| Honda, S; Kawahara, R; Kawaura, K; Miki, R; Noguchi, T; Shirasaki, T; Soeda, F; Takahama, K | 1 |
| Hamasaki, R; Shirasaki, T; Soeda, F; Takahama, K | 1 |
| Hamao, K; Hamasaki, R; Kawaura, K; Shirasaki, T; Soeda, F; Takahama, K | 1 |
| Hashimoto, K; Sato, K; Shirayama, Y; Suzuki, M; Takahashi, M | 1 |
| Fujioka, T; Fujisawa, TX; Kosaka, H; Kumazaki, H; Matsuzaki, H; Suzuki, H; Takiguchi, S; Tanaka, S; Tomoda, A; Yatsuga, C | 1 |
| Honda, S; Kawaura, K; Ogata, Y; Shirasaki, T; Soeda, F; Takahama, K | 1 |
| Hamasaki, R; Honda, I; Kawahara, R; Miki, R; Misumi, S; Shirasaki, T; Soeda, F; Takahama, K | 1 |
| Fukami, T; Fukuda, H; Hashizaki, K; Kanazawa, T; Kobayashi, C; Omotani, Y; Suzuki, N; Suzuki, T; Yamamoto, Y; Yoshimura, S | 1 |
| Akhondzadeh, S; Bagheri, S; Dehbozorghi, S; Mohammadi, MR; Moradi, K; Shokraee, K | 1 |
| Hayashi, M; Hirasawa-Inoue, A; Matsumoto, N; Matsumura, Y; Mizuguchi, T; Shirai, K; Sugai, K; Takase, C; Watanabe, A; Watanabe, T | 1 |
| Iwamori, S; Mizuno-Yasuhira, A; Nishino, I; Okada, T; Saito, K; Saito, T; Shinoda, S; Tomoda, A; Umeuchi, H; Urano, H; Yamashita, Y | 1 |
| Akhondzadeh, S; Hashemi, MG; Hoobehfekr, S; Kashefinejad, S; Moghaddam, HS; Pirmoradi, MM; Poopak, A; Sakenian, A; Shalbafan, M; Yarahmadi, M | 1 |
| Hayakawa, T; Muto, T; Okumura, A | 1 |
1 review(s) available for tipepidine and piperidines
| Article | Year |
|---|---|
[Novel antidepressant-like action of drugs possessing GIRK channel blocking action in rats].
Topics: Animals; Antidepressive Agents; Biogenic Monoamines; Brain; Cyclopentanes; Disease Models, Animal; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Humans; Male; Piperidines; Rats; Rats, Wistar | 2010 |
4 trial(s) available for tipepidine and piperidines
| Article | Year |
|---|---|
Effects of add-on tipepidine on treatment-resistant depression: an open-label pilot trial.
Topics: Adult; Antidepressive Agents; Cognition; Dehydroepiandrosterone Sulfate; Depressive Disorder, Treatment-Resistant; Dose-Response Relationship, Drug; Female; Humans; Hydrocortisone; Male; Memory; Motor Activity; Neuropsychological Tests; Pilot Projects; Piperidines; Swimming | 2016 |
Efficacy and safety of tipepidine as adjunctive therapy in children with attention-deficit/hyperactivity disorder: Randomized, double-blind, placebo-controlled clinical trial.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Methylphenidate; Piperidines; Psychiatric Status Rating Scales; Treatment Outcome | 2019 |
Using the drug repositioning approach to develop a novel therapy, tipepidine hibenzate sustained-release tablet (TS-141), for children and adolescents with attention-deficit/hyperactivity disorder.
Topics: Adolescent; Adult; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Drug Repositioning; Humans; Japan; Piperidines; Psychiatric Status Rating Scales; Tablets; Treatment Outcome | 2020 |
Efficacy and safety of tipepidine as adjunctive therapy in major depressive disorder: A randomized, double-blind, placebo-controlled clinical trial.
Topics: Adult; Citalopram; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Piperidines; Selective Serotonin Reuptake Inhibitors; Time Factors | 2021 |
20 other study(ies) available for tipepidine and piperidines
| Article | Year |
|---|---|
Inhibitory effects of non-narcotic antitussive drugs on cholinergically and non-cholinergically mediated neurogenic contractions of guinea-pig isolated bronchial muscle.
Topics: Animals; Antitussive Agents; Bronchi; Dextromethorphan; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Noscapine; Parasympathetic Nervous System; Piperidines | 1991 |
Drug interaction between cyproheptadine and tipepidine. Effect of single and repeated administrations.
Topics: Administration, Oral; Aminopyrine N-Demethylase; Animals; Blood; Cyproheptadine; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Injections, Intravenous; Male; Microsomes, Liver; Piperidines; Rats; Rats, Inbred Strains | 1991 |
On the possible convulsive activity of an antitussive piperidinic derivative ('tipepidina ibenzato') in man.
Topics: Adult; Electroencephalography; Female; Humans; Piperidines; Seizures | 1982 |
[Tipepidine poisoning].
Topics: Akathisia, Drug-Induced; Child, Preschool; Diazepam; Female; Humans; Medication Errors; Piperidines; Psychomotor Agitation | 1980 |
The preparation of rapidly disintegrating tablets in the mouth.
Topics: Administration, Oral; Chemistry, Pharmaceutical; Crystallization; Freeze Drying; Humans; Mannitol; Mouth; Piperidines; Porosity; Solubility; Sucrose; Tablets; Technology, Pharmaceutical; Tensile Strength | 2001 |
The centrally acting non-narcotic antitussive tipepidine produces antidepressant-like effect in the forced swimming test in rats.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Locomotion; Male; Motor Activity; Neuropsychological Tests; Piperidines; Rats; Rats, Wistar; Swimming; Time Factors | 2009 |
Fixed drug eruption induced by tipepidine hibenzate.
Topics: Antitussive Agents; Child; Drug Eruptions; Erythema; Humans; Japan; Male; Piperidines | 2010 |
The potent inhibitory effect of tipepidine on marble-burying behavior in mice.
Topics: Analysis of Variance; Animals; Behavior, Animal; Compulsive Behavior; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice; Motor Activity; Piperidines | 2011 |
Tipepidine enhances the antinociceptive-like action of carbamazepine in the acetic acid writhing test.
Topics: Acetates; Analgesics; Animals; Behavior, Animal; Carbamazepine; Drug Synergism; Male; Mice; Piperidines | 2011 |
Tipepidine hibenzate intoxication.
Topics: Antitussive Agents; Child, Preschool; Delirium; Drug Overdose; Humans; Male; Piperidines | 2011 |
Pharmacological mechanisms of antidepressant-like effect of tipepidine in the forced swimming test.
Topics: alpha-Methyltyrosine; Animals; Antidepressive Agents; Benzazepines; Drug Interactions; Fenclonine; Immobility Response, Tonic; Male; Motor Activity; Piperidines; Prazosin; Propranolol; Raclopride; Rats; Rats, Wistar; Yohimbine | 2012 |
Effect of tipepidine with novel antidepressant-like action on c-fos-like protein expression in rat brain.
Topics: Animals; Antidepressive Agents; Brain; Desipramine; Dose-Response Relationship, Drug; Gene Expression Regulation; Male; Piperidines; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Swimming | 2013 |
Tipepidine activates VTA dopamine neuron via inhibiting dopamine D₂ receptor-mediated inward rectifying K⁺ current.
Topics: Animals; Antidepressive Agents; Dopaminergic Neurons; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Immunohistochemistry; Patch-Clamp Techniques; Piperidines; Rats; Rats, Wistar; Receptors, Dopamine D2; Ventral Tegmental Area | 2013 |
Tipepidine increases dopamine level in the nucleus accumbens without methamphetamine-like behavioral sensitization.
Topics: Akathisia, Drug-Induced; Animals; Antidepressive Agents; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Male; Methamphetamine; Microdialysis; Motor Activity; Nucleus Accumbens; Piperidines; Rats, Sprague-Dawley | 2015 |
Effectiveness of oral tipepidine administration for children with attention deficit/hyperactivity disorder: A 4-week, open-label clinical study.
Topics: Administration, Oral; Attention Deficit Disorder with Hyperactivity; Child; Follow-Up Studies; Humans; Piperidines; Treatment Outcome | 2015 |
Tipepidine, a non-narcotic antitussive, exerts an antidepressant-like effect in the forced swimming test in adrenocorticotropic hormone-treated rats.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Benzazepines; Depression; Disease Models, Animal; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Fenclonine; Hormones; Imipramine; Immobility Response, Tonic; Locomotion; Male; Piperidines; Rats; Rats, Wistar; Serotonin Antagonists; Swimming | 2016 |
Effects of tipepidine on MK-801-induced cognitive impairment in mice.
Topics: Animals; Antidepressive Agents; Antitussive Agents; Clozapine; Cognitive Dysfunction; Disease Models, Animal; Dizocilpine Maleate; Dopaminergic Neurons; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Male; Mice; Patch-Clamp Techniques; Piperidines; Rats; Rats, Wistar; Schizophrenia; Ventral Tegmental Area | 2019 |
[Optimum Volume of Water Needed for the Paste State of Pediatric Powders: Considerations Based on Yield Values and Applications to Generic Medicine].
Topics: Adjuvants, Pharmaceutic; Ambroxol; Carbocysteine; Drug Compounding; Drugs, Generic; Ointments; Piperidines; Powders; Water | 2019 |
KCNT1-positive epilepsy of infancy with migrating focal seizures successfully treated with nonnarcotic antitussive drugs after treatment failure with quinidine: A case report.
Topics: Antitussive Agents; Dextromethorphan; Electroencephalography; Epilepsy; Humans; Infant; Magnetic Resonance Imaging; Male; Mutation; Nerve Tissue Proteins; Piperidines; Potassium Channels, Sodium-Activated; Quinidine; Seizures; Treatment Failure; Treatment Outcome | 2020 |
Tipepidine intoxication due to insufficient suspending of syrup formulation.
Topics: Antidepressive Agents; Humans; Piperidines | 2021 |