Compounds > tiopronin
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tiopronin and glycine

tiopronin has been researched along with glycine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19905 (45.45)18.7374
1990's1 (9.09)18.2507
2000's2 (18.18)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Brimacombe, KR; Dulcey, AE; Goldsborough, AS; Gottesman, MM; Griffiths, G; Hall, MD; Handley, MD; Kannan, P; Pluchino, KM1
Haldar, J; Lowbridge, J; Manning, M; Sawyer, WH1
Arrigoni Martelli, E; Bruno, G; Chassard, D; Douin, MJ; Giubilei, C; Marzo, A; Mignot, A; Nava, D; Thebault, JJ1
Besselievre, R; Bouboutou, R; Devin, J; Fournie-Zaluski, MC; Roques, BP; Waksman, G1
Bruno, M; Fruttero, B; Linari, F; Marangella, M1
CHO, Y; TANIFUJI, J1
IWATA, H; NAKAJIMA, K; SANTO, H1
Bond, JS; Hengst, JA1
Chen, SA; Chen, YC; Chen, YJ; Cheng, CC; Huang, JH; Lai, MS; Lin, CI; Lin, YK1

Trials

1 trial(s) available for tiopronin and glycine

ArticleYear
Pharmacokinetics of 2-(alpha-thenoylthio)-propionylglycine (TTPG) in healthy volunteers--an oral dose-proportionality investigation.
    Journal of pharmaceutical and biomedical analysis, 1992, Volume: 10, Issue:9

    Topics: Adult; Carboxylic Acids; Chromatography, High Pressure Liquid; Expectorants; Female; Glycine; Half-Life; Humans; Male; Spectrophotometry, Ultraviolet; Sulfides; Thiophenes; Tiopronin

1992

Other Studies

10 other study(ies) available for tiopronin and glycine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Collateral sensitivity of multidrug-resistant cells to the orphan drug tiopronin.
    Journal of medicinal chemistry, 2011, Jul-28, Volume: 54, Issue:14

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; HEK293 Cells; Humans; Multidrug Resistance-Associated Proteins; Orphan Drug Production; Paclitaxel; RNA Stability; RNA, Messenger; Structure-Activity Relationship; Tiopronin

2011
Synthesis and some pharmacological properties of [4-threonine, 7-glycine]oxytocin, [1-(L-2-hydroxy-3-mercaptopropanoic acid), 4-threonine, 7-glycine]oxytocin (hydroxy[Thr4, Gly7]oxytocin), and [7-Glycine]oxytocin, peptides with high oxytocic-antidiuretic
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:1

    Topics: Amino Acids, Sulfur; Glycine; Humans; Hydroxylation; Methods; Oligopeptides; Oxytocin; Threonine; Tiopronin; Vasopressins

1977
Binding of the bidentate inhibitor [3H]HACBO-Gly to the rat brain neutral endopeptidase "enkephalinase".
    Biochemical and biophysical research communications, 1985, Aug-30, Volume: 131, Issue:1

    Topics: Animals; Brain; Captopril; Cell Membrane; Corpus Striatum; Glycine; Hydroxylamines; Leucine; Male; Neprilysin; Protease Inhibitors; Rats; Rats, Inbred Strains; Substantia Nigra; Thiorphan; Tiopronin; Tissue Distribution

1985
[Cystinuria: clinical and therapeutic aspects].
    Bollettino chimico farmaceutico, 1982, Volume: 121, Issue:2

    Topics: Adolescent; Adult; Aged; Child; Cystinuria; Drug Evaluation; Glycine; Humans; Kinetics; Middle Aged; Penicillamine; Sulfides; Thiophenes; Tiopronin

1982
[STUDY ON THE USE OF THIOLA IN SKIN DISEASES].
    Hifuka kiyo. Acta dermatologica, 1964, Volume: 59

    Topics: Drug Therapy; Fabaceae; Glycine; Humans; Research; Skin Diseases; Sulfhydryl Compounds; Tiopronin

1964
[THE EFFECT OF ALPHA-THIOLA (ALPHA-MERCAPTO-PROPIONYL-GLYCINE) ON THE LEUKOPENIA INDUCED BY THE TREATMENT WITH SOME ANTICANCER AGENTS].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1964, Sep-20, Volume: 60

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Glycine; Leukopenia; Mice; Pharmacology; Propionates; Rabbits; Research; Sulfhydryl Compounds; Thiotepa; Tiopronin; Toxicology

1964
Transport of meprin subunits through the secretory pathway: role of the transmembrane and cytoplasmic domains and oligomerization.
    The Journal of biological chemistry, 2004, Aug-13, Volume: 279, Issue:33

    Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Caseins; Cell Line; Cell Membrane; Chromatography; Culture Media; Cytoplasm; Dimerization; Disulfides; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Gene Deletion; Glycine; Glycoside Hydrolases; Golgi Apparatus; Humans; Immunoblotting; Leucine; Metalloendopeptidases; Mice; Models, Biological; Molecular Sequence Data; Mutagenesis; Mutation; Plasmids; Protein Structure, Tertiary; Protein Transport; Recombinant Fusion Proteins; Tiopronin

2004
Hypoxia and reoxygenation modulate the arrhythmogenic activity of the pulmonary vein and atrium.
    Clinical science (London, England : 1979), 2012, Volume: 122, Issue:3

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Atrial Fibrillation; Blotting, Western; Chloramphenicol; Glyburide; Glycine; Heart Atria; HSP70 Heat-Shock Proteins; Hypoglycemic Agents; Hypoxia; In Vitro Techniques; Male; Oxygen; Pinacidil; Protein Synthesis Inhibitors; Pulmonary Veins; Rabbits; Reactive Oxygen Species; Tiopronin; Vasodilator Agents

2012