Page last updated: 2024-08-16

tiopronin and acetaminophen

tiopronin has been researched along with acetaminophen in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19907 (58.33)18.7374
1990's1 (8.33)18.2507
2000's2 (16.67)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Davis, M; Williams, R1
Davis, M; Labadarios, D; Portmann, B; Williams, R1
Labadarios, D; Williams, RS1
Harman, AW; Self, G1
Curzio, M; Flaccavento, C; Negro, F; Paradisi, L; Torrielli, MV1
Massey, TE; McElligott, TF; Racz, WJ; Walker, RM1
Davis, M; Smith, HM; Tredger, JM; Williams, R1
Sakr, SA1

Reviews

1 review(s) available for tiopronin and acetaminophen

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

11 other study(ies) available for tiopronin and acetaminophen

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Therapeutic aspects of paracetamol overdose including management of acute liver failure.
    Acta pharmacologica et toxicologica, 1977, Volume: 41 Suppl 2

    Topics: Acetaminophen; Chemical and Drug Induced Liver Injury; Cysteamine; Humans; Tiopronin

1977
Paracetamol-induced hepatic necrosis in the mouse-relationship between covalent binding, hepatic glutathione depletion and the protective effect of alpha-mercaptopropionylglycine.
    Biochemical pharmacology, 1977, Jan-01, Volume: 26, Issue:1

    Topics: Acetaminophen; Amino Acids, Sulfur; Animals; Chemical and Drug Induced Liver Injury; Glutathione; Liver; Male; Mice; Time Factors; Tiopronin

1977
Paracetamol, alpha-mercaptopropionyl glycine and some observations on the toxicity of protective agents.
    The Journal of international medical research, 1976, Volume: 4, Issue:4 Suppl

    Topics: Acetaminophen; Amino Acids, Sulfur; Animals; Cysteamine; Glutathione; Liver; Male; Mice; Tiopronin

1976
Comparison of the protective effects of N-acetylcysteine, 2-mercaptopropionylglycine and dithiothreitol against acetaminophen toxicity in mouse hepatocytes.
    Toxicology, 1986, Volume: 41, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Amino Acids, Sulfur; Animals; Cells, Cultured; Dithiothreitol; Glutathione; Liver; Male; Mice; Tiopronin

1986
[Susceptibility of the liver to lipid peroxidation after treatment with paracetamol].
    Bollettino della Societa italiana di biologia sperimentale, 1981, Feb-15, Volume: 57, Issue:3

    Topics: Acetaminophen; Adenosine Triphosphatases; Animals; Cell Membrane; Cysteine; Glutathione; Lipid Metabolism; Liver; Male; Microsomes, Liver; Nucleotidases; Rats; Tiopronin

1981
Ultrastructural effects of acetaminophen in isolated mouse hepatocytes.
    Experimental and molecular pathology, 1983, Volume: 39, Issue:2

    Topics: Acetaminophen; Acetylcysteine; Animals; Cell Survival; Cytoplasm; Liver; Male; Mice; Microscopy, Electron; Microvilli; Tiopronin

1983
Effects of sulphur-containing compounds on paracetamol activation and covalent binding in a mouse hepatic microsomal system.
    Toxicology letters, 1980, Volume: 5, Issue:5

    Topics: Acetaminophen; Acetylcysteine; Animals; Biotransformation; Cysteamine; In Vitro Techniques; Male; Methionine; Mice; Microsomes, Liver; Mixed Function Oxygenases; Sulfur; Tiopronin

1980
Effect of thiola on acetaminophen induced hepatic necrosis in mice.
    Bulletin of environmental contamination and toxicology, 1993, Volume: 51, Issue:6

    Topics: Acetaminophen; Animals; Behavior, Animal; Chemical and Drug Induced Liver Injury; Drug Interactions; Liver; Liver Diseases; Male; Mice; Mice, Inbred Strains; Necrosis; Tiopronin

1993