timolol has been researched along with pyrazines in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (96.55) | 18.7374 |
| 1990's | 1 (3.45) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mikkelsen, E; Pedersen, OL | 2 |
| Lederballe Pedersen, O | 1 |
| Castenfors, H | 1 |
| Overlack, A; Stumpe, KO | 1 |
| Bergis, K | 1 |
| Chappin, JJ; Henquet, JW; Hintzen, AH; Slagboom, G | 1 |
| Brailovsky, D | 1 |
| Agabiti-Rosei, E; Alicandri, C; Ambrosioni, E; Magnani, B; Miele, N; Muiesan, G | 1 |
| Vorburger, C | 1 |
| Chiou, GC; Lei, XL; Li, BH; Shen, ZF; Yan, HY | 1 |
| Lehtonen, A; Lindroos, M | 1 |
| Currie, WJ; Isitt, VL; VandenBurg, MJ; Young, JH | 1 |
| Arr, SM; Wight, L; Woollard, ML; Young, JH | 1 |
| Obel, AO | 1 |
| Cooper, WD; Currie, WJ; Vandenburg, MJ | 1 |
| Knauf, H; Steim, H | 1 |
| Gould, BA; Hornung, RS; Kieso, H; Raftery, EB | 2 |
| Arr, S; Parry, EE; Tait, D | 1 |
| Brown, JL; Chrysant, SG; Hagstrom, D | 1 |
| Burns, DG; Pittaway, D | 1 |
| Pittaway, D | 1 |
| Andersson, PO; Henning, R; Karlberg, BE; Lins, LE; Nilsson, OR; Odar-Cederlöf, I; Tolagen, K | 1 |
| Ballo, M; Cospite, M; Ferrara, F; Lo Presti, T; Meli, F; Milio, G; Raimondi, F | 1 |
| Grimshaw, JJ; Jaffé, G; Vallé-Jones, JC; Warnock, JM | 1 |
| Enenkel, W; Nobis, H; Pollak, H; Prachar, H | 1 |
| Albanesi Filho, FM; Brandão, AP; Oigman, W | 1 |
| Pedersen, TR | 1 |
17 trial(s) available for timolol and pyrazines
| Article | Year |
|---|---|
Beta-blockers and uric-acid excretion.
Topics: Amiloride; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Propanolamines; Pyrazines; Timolol; Uric Acid | 1978 |
[Treatment of mild to moderate essential arterial hypertension with timolol alone and in combination with hydrochlorothiazide + amiloride. A multicenter, double-blind, cross-over study].
Topics: Amiloride; Clinical Trials as Topic; Creatinine; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Placebos; Potassium; Propanolamines; Pyrazines; Timolol | 1977 |
Long term effect of timolol and hydrochlorothiazide, or hydrochlorothiazide and amiloride, in essential hypertension.
Topics: Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Propanolamines; Pulse; Pyrazines; Time Factors; Timolol | 1977 |
[Antihypertensive effect of a fixed beta-receptor blockader-diuretic combination during a single daily administration].
Topics: Adult; Amiloride; Clinical Trials as Topic; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Placebos; Propanolamines; Pyrazines; Timolol | 1978 |
Individual factors influencing the response to a beta-adrenergic blocking agent given alone and in combination with a diuretic on arterial hypertension.
Topics: Adult; Aging; Amiloride; Body Weight; Clinical Trials as Topic; Drug Therapy, Combination; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Propanolamines; Pyrazines; Time Factors; Timolol | 1979 |
The use of timolol maleate alone and with diuretic in the treatment of essential hypertension.
Topics: Adult; Aged; Amiloride; Clinical Trials as Topic; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Placebos; Potassium; Propanolamines; Pyrazines; Timolol | 1976 |
Evaluation of the effect of timolol alone and in combination with hydrochlorothiazide and amiloride in the treatment of mild to moderate arterial hypertension: a double-blind, controlled study.
Topics: Adult; Amiloride; Clinical Trials as Topic; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propanolamines; Pyrazines; Timolol | 1976 |
[The anti-hypertensive effect of timolol maleate (blocadren) in gradated combination with a diuretic].
Topics: Amiloride; Benzothiadiazines; Diuretics; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Propanolamines; Pyrazines; Sodium Chloride Symporter Inhibitors; Timolol | 1976 |
Timolol and a hydrochlorothiazide-amiloride combination in the treatment of essential hypertension in young and middle-aged patients: a comparative study with once-daily administration.
Topics: Adult; Amiloride; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Pyrazines; Random Allocation; Timolol | 1984 |
Comparison of a fixed ratio combination of hydrochlorothiazide, amiloride and timolol ('Moducren') given once versus twice daily in mild to moderate hypertension.
Topics: Adult; Aged; Amiloride; Blood Pressure; Drug Administration Schedule; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines; Time Factors; Timolol | 1984 |
Efficacy and tolerance of a fixed ratio combination of hydrochlorothiazide, amiloride and timolol, taken before or after food, in the treatment of hypertension.
Topics: Adult; Aged; Amiloride; Drug Combinations; Female; Food; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines; Timolol | 1984 |
A comparison of timolol plus hydrochlorothiazide plus amiloride and methyldopa in essential hypertension in Black Africans.
Topics: Adult; Amiloride; Antihypertensive Agents; Black People; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Kenya; Male; Methyldopa; Middle Aged; Pyrazines; Random Allocation; Timolol | 1983 |
A general practice study of timolol/hydrochlorothiazide/amiloride ('Moducren'), a new therapy for hypertension, and the doctor's influence on management.
Topics: Adult; Aged; Amiloride; Blood Pressure; Drug Combinations; Family Practice; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Patient Compliance; Propanolamines; Pyrazines; Timolol | 1983 |
Combination of timolol maleate, hydrochlorothiazide and amiloride hydrochloride in the treatment of hypertension: A multicentre trial.
Topics: Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Maleates; Middle Aged; Placebos; Potassium; Propanolamines; Pyrazines; Timolol; Urate Oxidase | 1980 |
Evaluation of a fixed combination of timolol maleate, hydrochlorothiazide and amiloride hydrochloride in the treatment of hypertension: A long-term multicentre trial.
Topics: Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Diastole; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Patient Compliance; Potassium; Propanolamines; Pulse; Pyrazines; Systole; Time Factors; Timolol; Uric Acid | 1980 |
Timolol and hydrochlorothiazide-amiloride in primary hypertension.
Topics: Adult; Amiloride; Blood Pressure; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propanolamines; Pyrazines; Renin; Timolol | 1980 |
[Hypertension treated with hydrochlorothiazide/amilorid and timolol maleate].
Topics: Adult; Amiloride; Blood Pressure; Double-Blind Method; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Propanolamines; Pyrazines; Timolol | 1980 |
12 other study(ies) available for timolol and pyrazines
| Article | Year |
|---|---|
[Results of a field study with Moducrin in 12596 hypertensive patients].
Topics: Amiloride; Drug Combinations; Drug Evaluation; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propanolamines; Pyrazines; Timolol | 1979 |
Concomitant administration of timolol and hydrochlorothiazide/amiloride in hypertensive patients. Results of a titration study.
Topics: Adult; Aged; Amiloride; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propanolamines; Pyrazines; Timolol | 1978 |
Ocular and cardiovascular pharmacology of tetramethylpyrazine isolated from Ligusticum wallichii Franch.
Topics: Animals; Blood Pressure; Choroid; Coronary Circulation; Female; Guinea Pigs; Heart Rate; Hemodynamics; In Vitro Techniques; Male; Pyrazines; Rabbits; Regional Blood Flow; Retinal Vessels; Stereoisomerism; Timolol; Vasodilator Agents | 1991 |
Do elderly patients respond differently to treatment with Moducren?
Topics: Adult; Age Factors; Aged; Amiloride; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines; Timolol | 1984 |
[Reliable lowering of blood pressure with one tablet of Moducrin daily (author's transl)].
Topics: Amiloride; Blood Pressure; Circadian Rhythm; Drug Combinations; Drug Evaluation; Humans; Hydrochlorothiazide; Hypertension; Propanolamines; Pyrazines; Timolol | 1980 |
[Therapy of hypertension with timolol, hydrochlorothiazide and amiloride].
Topics: Amiloride; Humans; Hydrochlorothiazide; Hypertension; Propanolamines; Pyrazines; Timolol | 1983 |
Antihypertensive and metabolic effects of hydrochlorothiazide, amiloride-hydrochlorothiazide, and timolol.
Topics: Amiloride; Antihypertensive Agents; Blood Pressure; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Potassium; Propanolamines; Pyrazines; Timolol | 1983 |
[Antihypertensive effects of timolol and of the combination timolol, amiloride and hydrochlorothiazide].
Topics: Adult; Amiloride; Blood Pressure; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Propanolamines; Pyrazines; Renin; Sodium; Timolol | 1981 |
A comparative study of Moducren and Moduretic and their effect on plasma potassium in essential hypertension.
Topics: Adult; Aged; Amiloride; Antihypertensive Agents; Body Weight; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Propanolamines; Pyrazines; Random Allocation; Timolol | 1982 |
The effect of a combination of timolol, hydrochlorothiazide and amiloride on 24 hour blood pressure control using ambulatory intra-arterial monitoring.
Topics: Adult; Amiloride; Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Drug Combinations; Humans; Hydrochlorothiazide; Male; Middle Aged; Monitoring, Physiologic; Propanolamines; Pyrazines; Timolol | 1982 |
[Moducrin--a new combined preparation in the treatment of hypertension (author's transl)].
Topics: Adult; Amiloride; Antihypertensive Agents; Blood Pressure; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propanolamines; Prospective Studies; Pyrazines; Timolol | 1981 |
[Treatment of arterial hypertension: comparative study of atenolol + chlorthalidone vs. timolol maleate-hydrochlorthiazide-amiloride association].
Topics: Adult; Aged; Amiloride; Atenolol; Blood Pressure; Chlorthalidone; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propanolamines; Pyrazines; Timolol | 1981 |