timolol has been researched along with methyldopa in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (48.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (20.00) | 29.6817 |
| 2010's | 8 (32.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Lund-Johansen, P | 1 |
| Spira, M | 1 |
| Goldet, L; Jouve, A; Mathieu, M | 1 |
| Brunner, HR; Nussberger, J; Waeber, B | 2 |
| Brunner, HR; Graf, HJ; Jaussi, A; Porchet, M; Rion, F; Waeber, B | 2 |
| Ellis, R; Wood, SJ | 1 |
| Obel, AO | 1 |
| Hagelund, CH; Tretli, S | 1 |
| De Swiet, M; Fidler, J; Smith, V | 1 |
2 review(s) available for timolol and methyldopa
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Are surgery blood pressure measurements adequate to evaluate the efficacy of antihypertensive drugs?
Topics: Antihypertensive Agents; Blood Pressure Determination; Clinical Trials as Topic; Humans; Hypertension; Methyldopa; Placebos; Surgical Procedures, Operative; Timolol | 1984 |
9 trial(s) available for timolol and methyldopa
| Article | Year |
|---|---|
A crossover comparison of a timolol/bendrofluazide combination and methyldopa in essential hypertension.
Topics: Adult; Aged; Bendroflumethiazide; Blood Pressure; Drug Combinations; Female; Heart Rate; Humans; Hypertension; Male; Methyldopa; Middle Aged; Timolol | 1977 |
Results of a national therapeutic trial conducted in 10,000 hypertensive patients by 2000 general practitioners.
Topics: Adult; Aged; Amiloride; Antihypertensive Agents; Drug Tolerance; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Timolol | 1978 |
Shortcomings of office blood pressures in assessing antihypertensive therapy.
Topics: Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Clonidine; Diuretics; Humans; Hypertension; Methyldopa; Timolol | 1985 |
Blood pressure response to antihypertensive therapy: ambulatory versus office blood pressure readings.
Topics: Activities of Daily Living; Adult; Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Double-Blind Method; Drug Evaluation; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged; Office Visits; Timolol | 1985 |
[Usefulness of ambulatory registration of arterial pressure in therapeutic trials of antihypertensive agents].
Topics: Adult; Aged; Ambulatory Care; Amiloride; Antihypertensive Agents; Blood Pressure Determination; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Male; Methyldopa; Middle Aged; Private Practice; Timolol | 1985 |
Are surgery blood pressure measurements adequate to evaluate the efficacy of antihypertensive drugs?
Topics: Antihypertensive Agents; Blood Pressure Determination; Clinical Trials as Topic; Humans; Hypertension; Methyldopa; Placebos; Surgical Procedures, Operative; Timolol | 1984 |
A comparison of timolol plus hydrochlorothiazide plus amiloride and methyldopa in essential hypertension in Black Africans.
Topics: Adult; Amiloride; Antihypertensive Agents; Black People; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Kenya; Male; Methyldopa; Middle Aged; Pyrazines; Random Allocation; Timolol | 1983 |
[Clinical trials with hypertensive patients in general practice].
Topics: Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Random Allocation; Timolol | 1980 |
A randomized study comparing timolol and methyldopa in hospital treatment of puerperal hypertension.
Topics: Adult; Female; Humans; Hypertension; Methyldopa; Pregnancy; Propanolamines; Puerperal Disorders; Random Allocation; Timolol | 1982 |
15 other study(ies) available for timolol and methyldopa
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
alpha-Methyldopa and beta-blockers in hypertension--a comparison of their haemodynamic effects.
Topics: Adrenergic beta-Antagonists; Alprenolol; Hemodynamics; Humans; Hypertension; Methyldopa; Metoprolol; Physical Exertion; Propranolol; Time Factors; Timolol | 1978 |
The use of timolol/bendrofluazide (Prestim) in the treatment of hypertensive patients failing to respond to other antihypertensives.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Bendroflumethiazide; Diuretics; Drug Combinations; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged; Timolol | 1983 |
[Comparison between timolol maleate and alphamethyldopa in longterm treatment of essential hypertension (author's transl)].
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male; Methyldopa; Middle Aged; Propanolamines; Timolol | 1981 |