timolol has been researched along with ici 118551 in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (46.67) | 18.7374 |
| 1990's | 7 (46.67) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Carrupt, PA; el Tayar, N; Testa, B; Van de Waterbeemd, H | 1 |
| Baker, JG | 1 |
| Erickson-Lamy, KA; Nathanson, JA | 1 |
| Armour, JA; Boudreau, G; Cardinal, R; Watson-Wright, W | 1 |
| Bast, A; Beusenberg, FD; Leurs, R; Timmerman, H; Van Amsterdam, JG | 1 |
| Nathanson, JA | 3 |
| Chen, J; Padillo, E; Ruiz, G; Woodward, DF | 1 |
| Gerber, U; Niemeyer, G; Uji, Y | 1 |
| Ali-Melkkilä, T; Iisalo, E; Kaila, T; Saari, KM; Vuori, ML | 2 |
| Li, M; Lu, Y; Shen, Y | 1 |
| Abuin, L; Cotecchia, S; Lattion, A; Nenniger-Tosato, M | 1 |
1 review(s) available for timolol and ici 118551
| Article | Year |
|---|---|
Modeling of beta-adrenoceptors based on molecular electrostatic potential studies of agonists and antagonists.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Models, Molecular; Receptors, Adrenergic, beta; Structure-Activity Relationship | 1988 |
2 trial(s) available for timolol and ici 118551
| Article | Year |
|---|---|
Absorption of ocular timolol: drug concentrations and beta-receptor binding activity in the aqueous humour of the treated and contralateral eye.
Topics: Absorption; Administration, Topical; Adrenergic beta-Antagonists; Aged; Animals; Aqueous Humor; Cataract Extraction; Heart Rate; Humans; Lenses, Intraocular; Ophthalmic Solutions; Propanolamines; Rabbits; Radioligand Assay; Rats; Receptors, Adrenergic, beta; Timolol | 1993 |
Beta 1- and beta 2-antagonist activity of topically applied betaxolol and timolol in the systemic circulation.
Topics: Administration, Topical; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Betaxolol; Humans; Middle Aged; Propanolamines; Radioligand Assay; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Timolol | 1993 |
12 other study(ies) available for timolol and ici 118551
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Algorithms; Animals; Cell Line; CHO Cells; Cricetinae; Dioxoles; Humans; Propanolamines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3 | 2005 |
Epinephrine increases facility of outflow and cyclic AMP content in the human eye in vitro.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Aqueous Humor; Cyclic AMP; Epinephrine; Humans; Middle Aged; Perfusion; Propanolamines; Radioimmunoassay; Receptors, Adrenergic, beta; Timolol; Trabecular Meshwork | 1992 |
Beta 1- and beta 2-adrenoceptor subtypes in canine intrathoracic efferent sympathetic nervous system regulating the heart.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Atropine; Axons; Dogs; Efferent Pathways; Electric Stimulation; Female; Ganglia, Sympathetic; Heart Conduction System; Isoproterenol; Male; Myocardial Contraction; Propanolamines; Receptors, Adrenergic, beta; Stellate Ganglion; Sympathetic Nervous System; Timolol | 1991 |
Identification of beta 2-adrenoceptors on guinea pig alveolar macrophages using (-)-3-[125I]iodocyanopindolol.
Topics: Adrenergic beta-Antagonists; Animals; Binding, Competitive; Cell Membrane; Guinea Pigs; Iodine Radioisotopes; Iodocyanopindolol; Macrophages; Male; Pindolol; Propanolamines; Pulmonary Alveoli; Receptors, Adrenergic, beta; Timolol | 1990 |
Differential inhibition of beta adrenergic receptors in human and rabbit ciliary process and heart.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Adult; Aged; Animals; Ciliary Body; Dose-Response Relationship, Drug; Heart Rate; Humans; Isoproterenol; Kinetics; Male; Methylation; Middle Aged; Myocardium; Propanolamines; Propranolol; Rabbits; Receptors, Adrenergic, beta; Timolol | 1985 |
Pharmacological characterization of beta-adrenoceptor subtype involvement in the ocular hypotensive response to beta-adrenergic stimulation.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Dose-Response Relationship, Drug; Female; Intraocular Pressure; Isoproterenol; Male; Pindolol; Propanolamines; Rabbits; Receptors, Adrenergic, beta; Time Factors; Timolol | 1986 |
Stereospecificity of beta adrenergic antagonists: R-enantiomers show increased selectivity for beta-2 receptors in ciliary process.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Betaxolol; Ciliary Body; Heart; Isoproterenol; Male; Metoprolol; Myocardium; Propanolamines; Rabbits; Receptors, Adrenergic, beta; Stereoisomerism; Structure-Activity Relationship; Timolol | 1988 |
[Effect of beta-blockers on retinal function in vitro].
Topics: Adrenergic beta-Antagonists; Animals; Cats; Dose-Response Relationship, Drug; Evoked Potentials, Visual; Optic Nerve; Perfusion; Propanolamines; Propranolol; Retina; Timolol | 1988 |
ICI 118,551: an effective ocular hypotensive agent with selectivity for the ciliary process beta 2-adrenoceptor and with minimal cardiac side effects.
Topics: Adenylyl Cyclase Inhibitors; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Ciliary Body; Heart Rate; In Vitro Techniques; Intraocular Pressure; Isoproterenol; Lung; Propanolamines; Rabbits; Receptors, Adrenergic, beta; Timolol | 1984 |
[The effects of adrenergic antagonists on epinephrine determined by the assay of adenosine 3',5'-monophosphate in bovine trabecular cells in vitro].
Topics: Adrenergic beta-Antagonists; Animals; Bisoprolol; Cattle; Cells, Cultured; Cyclic AMP; Epinephrine; Propanolamines; Timolol; Trabecular Meshwork | 1997 |
Constitutively active mutants of the beta1-adrenergic receptor.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Amino Acid Substitution; Betaxolol; Carbazoles; Carvedilol; Cell Line; Cyclic AMP; Epinephrine; Humans; Imidazoles; Isoproterenol; Labetalol; Point Mutation; Practolol; Propanolamines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Recombinant Proteins; Timolol | 1999 |