Page last updated: 2024-08-16

timolol and eye

timolol has been researched along with eye in 141 studies

Research

Studies (141)

TimeframeStudies, this research(%)All Research%
pre-199049 (34.75)18.7374
1990's39 (27.66)18.2507
2000's28 (19.86)29.6817
2010's24 (17.02)24.3611
2020's1 (0.71)2.80

Authors

AuthorsStudies
Le Douarec, JC; Lotti, VJ; Schmitt, C; Vareilles, P1
D'Anna, SA; Koslov, S; Kues, HA; Lutty, GA; McLeod, DS; Monahan, JC1
Lee, VH; Ohdo, S; Zhu, J1
Järvinen, K; Urtti, A1
Baba, H; Tokoro, T; Yamazaki, S1
Kitada, S; Lee, DA; Nguyen, KD; Shapourifar-Tehrani, S; Williams, DE1
Lee, VH; Moy, KC; Podder, SK1
Bloedow, DC; Ellis, PP; Pfoff, DS; Riegel, MR; Wu, PY1
Cruess, DF; Kao, SF; Kincaid, MC; Rabbani, R; Skuta, GL; Smith, DL1
Smith, SE; Trew, DR1
Lee, VH; Luo, AM; Sasaki, H1
Chiou, GC; Li, BH; Shen, ZF; Zhao, F1
Haruta, Y; Hill, JM; Kaufman, HE; Reidy, JJ; Rootman, DS1
Chiou, FY; Chiou, GC; Li, BH; Ruiz-Razura, A1
Bartels, SP; Belmonte, C; Liu, JH; Neufeld, AH1
Fredj, D; Lapalus, P; Moulin, G1
Chen, J; Dowling, MC; Feldmann, BJ; Woodward, DF1
Hesse, R; Kendall, K; Lavin, P; Mundorf, T; Nardin, G; Zimmerman, TJ1
Bundgaard, H; Lee, VH; Potter, DE; Shumate, DJ1
Briones, O; Dawson, CR; Santos, C1
Araullo-Cruz, T; Gordon, YJ; Harwick, J; Romanowski, E1
Berman, E; Dudley, JB; Haruta, Y; Hill, JM; Kwon, BS; Maguire, LJ; Shimomura, Y1
Aula, P; Huupponen, R; Kaila, T; Salminen, L1
Fukado, Y; Inatomi, M; Koide, R; Maeda, I; Oguchi, K; Uchida, E; Ueda, T; Yasuhara, H1
Pipkin, JD; Repta, AJ; Rork, G; Sendo, T; Urtti, A1
Huupponen, R; Kaila, T; Salminen, L1
Green, K; Hatchett, TL1
Shin, DH1
Chiou, GC; Yan, HY1
Bullimore, MA; Gilmartin, B1
Albert, J; Davidson, J; Putterman, GJ1
Caruso, C; Cennamo, G; Nastri, G1
Trawick, AB1
Kodama, T1
Green, K; Schermerhorn, J1
Chiou, GC; Lauber, JK; McLaughlin, MA1
Innemee, HC; Ros, FE; van Zwieten, PA1
Bartels, SP; Jumblatt, MM; Neufeld, AH; Roth, HO1
Colasanti, BK; Trotter, RR1
Bengtsson, E; Holmdahl, G1
Avaux, G; Missotten, L; Van Tornout, I; Van Wijnendaele, J1
Araie, M; Ishii, Y; Kitagawa, M; Sakai, Y; Takase, M; Yokoyama, Y1
Chou, A; Go, F; Hori, S; Komatsu, M; Takase, M1
Kaufman, HE; Leader, B; Zimmerman, TJ1
Folberg, R; Hargett, NA; McLean, IW; Weaver, JE1
Petursson, GJ; Shock, JP; Stone, JE; Zalta, AH1
Doyle, WJ; Meeks, RH; Weber, PA1
Aziz, MZ; Green, K; Jay, WM1
Bartels, SP; Liu, JH; Neufeld, AH1
Kramer, P; Ritch, R1
Baumann, JD; Hetherington, J; Zimmerman, TJ1
Fraunfelder, FT; Meyer, SM1
Salminen, L; Urtti, A1
Gilmartin, B; Hogan, RE; Thompson, SM1
Keates, EU; Stone, R1
Anderson, J; Blumenthal, M; Chen, CC; Duzman, E; Twizer, H1
Babický, A; Obenberger, J; Růzicková, E; Výborný, P1
Araie, M; Kitagawa, M; Takase, M; Yokoyama, Y1
Blanchet, LM; Coupland, SG; Kirkham, TH; Nelson, DE1
LeDouarec, JC; Lotti, VJ; Schmitt, CJ1
Bosem, ME; Lusky, M; Morsman, CD; Weinreb, RN1
Cunliffe, I; McIntyre, C; Rees, R; Rennie, I1
Kaila, T; Vuori, ML1
Kaila, T; Rouhiainen, H; Saano, V; Urtti, A1
Becker, MA; Liu, GS; Menon, IA; Persad, SD; Thibodeau, JR; Trope, GE1
Kompella, UB; Lee, VH; Lee, YH1
Chetoni, P; Lee, VH; Li, SY; Saettone, MF; Sasaki, H1
Urtti, A1
Freedman, NJ; Freedman, SF; Keates, EU; Lobaugh, B; Ollie, A; Samsa, GP; Shields, MB1
Claridge, KG1
Crandall, AS; Mamalis, N; Sharir, M; Zimmerman, TJ1
Carr, RD; Humphries, RG; Millar, JC; Wilson, WS1
Acheampong, AA; Breau, A; Lam, S; Luo, W; Shackleton, M; Tang-Liu, DD1
Chen, IJ; Chiou, GC; Hong, SJ; Liu, SX; Sheu, MM; Wu, BN1
Cheng, YL; Friedrich, SW; Rootman, DS; Saville, BA1
Hong, SJ; Wang, HZ; Wu, KY1
Chetoni, P; Perini, G; Saettone, MF; Vigetti, B1
Ichikawa, M; Kawakami, S; Mukai, T; Nakamura, J; Nishida, K; Sasaki, H; Yamamura, K1
Crichton, AC; Drance, SM; Greve, EL; Hoyng, PF; Mills, RP; Rulo, AH1
Huang, JK; Hung, PT; Shih, YF; Wang, TH1
Abiko, T; Ishiko, S; Kato, Y; Kitaya, N; Mori, F; Nagaoka, T; Ogasawara, H; Yoshida, A1
Barros, MD; Bodor, N; Farag, HH; Prokai, L; Somogyi, G; Wu, WM1
Berrino, L; Boldrini, E; Imperatore, A; Lampa, E; Matera, MG; Rossi, F; Russo, F1
Jaitely, V; Mysore, N; Venkatesan, N; Vyas, SP1
Ichikawa, M; Mukai, T; Nakamura, J; Nakashima, M; Nishida, K; Sasaki, H; Yamamura, K1
Cantor, LB; Evans, DW; Harris, A1
Järvinen, K; Paronen, P; Sääskilahti, M; Svarfvar, B; Tarvainen, T; Urtii, A1
Becker, R; Pillunat, LE; Schmidt, KG; von Rückmann, A1
Cole, C; Garzozi, H; Harris, A; Jonescu-Cuypers, CP; Kagemann, L; Martin, B; Nowacki, EA1
Ishibashi, Y; Muto, T; Roy, S; Sato, T1
Mao, J; Sui, R; Zhao, J1
Izumi, H; Karita, K; Naito, A; Tamai, M1
Archibald, ML; Chauhan, BC; Kelly, ME; LeVatte, TL; Tan, AY; Tremblay, F1
Calissendorff, B; Grunge-Lowerud, A; Högberg, G; Sjöquist, B1
Gressnerová, S; Oláh, Z; Veselá, A; Veselovský, J1
Kaila, T; Korte, JM; Saari, KM1
Bucci, MG; Centofanti, M; Gregori, D; Manni, G; Migliardj, R; Oddone, F; Scipioni, M1
Recker, K1
Brignoli, R; Mermoud, A; Ravinet, E1
Agarwal, HC; Gupta, V; Sihota, R1
Ishibashi, T; Kinoshita, S; Yokoi, N1
Harris, A; Janulevicienë, I; Kagemann, L; McCranor, L; Siesky, B1
Criado, S; García, NA1
Aggarwal, D; Kaur, IP1
Aggermann, T; Buehl, W; Eichler, HG; Fuchsjäger-Mayrl, G; Kolodjaschna, J; Polska, E; Rainer, G; Schmetterer, L; Vass, C; Wally, B; Weigert, G1
Chauhan, A; Zhu, H1
Martínez, A; Sánchez, M1
Hardarson, SH; Loftsson, T; Níelsdóttir, GE; Sigurdsson, HH; Stefánsson, E; Valgeirsson, J1
Harris, A; Malinovsky, VE; McCranor, L; Rechtman, E; Siesky, B; Sines, D; Yung, CW; Zalish, M1
Li, R; Liu, JH; Nelson, TR; Weinreb, RN1
Ammon, DM; Borazjani, RN; Foster, WJ; Garcia, CA; Hacker, MC; Haesslein, A; Kunzler, JF; Mikos, AG; Salamone, JC; Ueda, H1
Higuchi, S; Kawazu, K; Kitahara, T; Nakamura, J; Nakashima, M; Nishida, K; Sakanaka, K; Sasaki, H; Tomonari, M1
Czechowicz-Janicka, K; Kałuzny, BJ; Kałuzny, J; Kecik, D; Sobecki, R; Stewart, JA; Stewart, WC1
Ajayi, BG; Ashaye, AO; Fasina, O1
Ammon, DM; Borazjani, RN; Hacker, MC; Haesslein, A; Kunzler, JF; Mikos, AG; Salamone, JC; Ueda, H1
Konstas, AG; Kozobolis, VP; Lasaridis, AN; Mikropoulos, D; Nelson, LA; Pikilidou, MI; Sarafidis, PA; Stewart, WC; Tsironi, S1
Bwatwa, J; Ehrlich, R; Harris, A; Kagemann, L; McCranor, L; Miller, B; Regev, G; Siesky, B; Stefansson, E1
García-Pérez, JL; González-Gordaliza, C; Muñoz-Negrete, FJ; Puerto-Hernández, B; Rebolleda Fernández, G1
Bastien, NR; Behki, R; Boucher, S; Crichton, AC; Harasymowycz, P; Hutnik, CM; Ibrahim, F; Liao, C; Rifkind, AW; Sampalis, JS; Solomon, L1
Daito, M; Hiraoka, T; Kiuchi, T; Okamoto, F; Oshika, T1
Hakkola, J; Mäenpää, J; Pelkonen, O; Vapaatalo, H; Volotinen, M1
Cai, SP; Liu, G; Liu, X; Pang, IH; Wang, H; Yan, N; Yu, W; Zeng, T1
Abrams, L; Cantor, L; Ehrlich, R; Harris, A; Hollander, DA; Rusia, D; Shoja, MM; Shoshani, Y; Siesky, B; Williams, JM1
Cunha-Júnior, Ada S; Faraco, AG; Fulgêncio, Gde O; Ribeiro, RR; Viana, FA; Yoshida, MI1
Ohguro, H; Ohguro, I1
Burke, MT; Carbia, BE; Chauhan, A; Peng, CC; Plummer, C1
Garhöfer, G; Hommer, A; Popa-Cherecheanu, A; Qiao, C; Resch, H; Schmetterer, L; Sperl, P1
Feke, GT; Pasquale, LR; Rhee, DJ; Turalba, AV1
Barros, Jde N; Faria, NV; Gomes, JÁ; Mello, PA; Montiani-Ferreira, F; Nogueira-Filho, PA; Russ, HH1
Carmichael, TR; Choonara, YE; du Toit, LC; Kumar, P; Moosa, RM; Pillay, V; Tomar, LK; Tyagi, C1
Backman, JT; Kautiainen, H; Mäenpää, J; Neuvonen, M; Neuvonen, PJ; Niemi, M; Volotinen-Maja, M1
Fukuda, M; Sasaki, H1
Bikiaris, DN; Karavas, E; Kostoglou, M; Koukaras, EN; Koutris, E; Siafaka, PI; Titopoulou, A1
Ha, SJ; Seo, du R1
Antopolsky, M; Hagström, M; Kidron, H; Latonen, S; Manzanares, JA; Rimpelä, AK; Schmitt, M; Urtti, A1
Aslan, CA; Baltepe Altıok, I; Eliacik, M; Gulkilik, G; Karaman Erdur, S; Kaya, F1
Cong, X; Molloy, BL; Watson, C1
Allemandi, DA; Arias, FJ; Fernández-Colino, A; Girotti, A; Palma, SD; Quinteros, DA1
Ma, F; Ma, H; Ma, J; Shang, Q; Su, J; Wang, X; Yu, J; Zhang, T1
Desai, AR; Maulvi, FA; Patil, RJ; Ranch, KM; Shah, DO; Shah, SA; Shukla, MR; Vaidya, RJ; Vyas, BA1
Babiskin, A; Chen, Z; Fan, J; German, C; Przekwas, A; Tan, ML; Walenga, R; Zhao, L1

Reviews

5 review(s) available for timolol and eye

ArticleYear
Advances in ocular pharmacology.
    Annual review of pharmacology and toxicology, 1980, Volume: 20

    Topics: Animals; Cannabis; Carbachol; Cytochalasin B; Epinephrine; Eye; Eye Diseases; Glaucoma; Humans; Idoxuridine; Interferons; Intraocular Pressure; Keratitis; Membranes, Artificial; Pharmaceutical Preparations; Timolol; Trifluridine; Vidarabine; Virus Diseases

1980
Delivery of antiglaucoma drugs: ocular vs systemic absorption.
    Journal of ocular pharmacology, 1994,Spring, Volume: 10, Issue:1

    Topics: Absorption; Animals; Biological Availability; Delayed-Action Preparations; Drug Delivery Systems; Eye; Glaucoma; Half-Life; Humans; Ophthalmic Solutions; Timolol

1994
Reduced intraocular pressure and increased ocular perfusion pressure in normal tension glaucoma: a review of short-term studies with three dose regimens of latanoprost treatment.
    Survey of ophthalmology, 1997, Volume: 41 Suppl 2

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Circadian Rhythm; Dose-Response Relationship, Drug; Eye; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol

1997
Four years later: a clinical update on latanoprost.
    European journal of ophthalmology, 2003, Volume: 13, Issue:2

    Topics: Antihypertensive Agents; Aqueous Humor; Blood Flow Velocity; Circadian Rhythm; Clinical Trials as Topic; Drug Therapy, Combination; Eye; Glaucoma, Angle-Closure; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Safety; Sulfonamides; Thiophenes; Timolol

2003
Metabolism of ophthalmic timolol: new aspects of an old drug.
    Basic & clinical pharmacology & toxicology, 2011, Volume: 108, Issue:5

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Eye; Glaucoma; Heart Rate; Humans; Intraocular Pressure; Liver; Timolol

2011

Trials

28 trial(s) available for timolol and eye

ArticleYear
Effects of eyelid closure and nasolacrimal duct occlusion on the systemic absorption of ocular timolol in human subjects.
    Journal of ocular pharmacology, 1986,Fall, Volume: 2, Issue:4

    Topics: Absorption; Administration, Topical; Adult; Eye; Eyelids; Female; Humans; Male; Nasolacrimal Duct; Timolol

1986
Tonic accommodation, cognitive demand, and ciliary muscle innervation.
    American journal of optometry and physiological optics, 1987, Volume: 64, Issue:1

    Topics: Accommodation, Ocular; Adult; Cognition; Eye; Humans; Male; Muscles; Optometry; Sympathetic Nervous System; Timolol

1987
Effect of topical timolol maleate on exercise performance.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1984, Volume: 102, Issue:10

    Topics: Administration, Topical; Adult; Clinical Trials as Topic; Double-Blind Method; Exercise Test; Eye; Female; Heart Rate; Humans; Male; Physical Exertion; Placebos; Random Allocation; Respiration; Timolol

1984
The effect of Timolol Maleate on tonic accommodation, tonic vergence, and pupil diameter.
    Investigative ophthalmology & visual science, 1984, Volume: 25, Issue:6

    Topics: Accommodation, Ocular; Eye; Eye Movements; Fixation, Ocular; Humans; Sympathetic Nervous System; Timolol

1984
Diacetyl derivative of nadolol. I. Ocular pharmacology and short-term ocular hypotensive effect in glaucomatous eyes.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1982, Volume: 100, Issue:12

    Topics: Absorption; Adult; Animals; Clinical Trials as Topic; Double-Blind Method; Eye; Female; Glaucoma, Open-Angle; Humans; Hydrolysis; Male; Nadolol; Ocular Hypertension; Propanolamines; Rabbits; Timolol

1982
The effect of topical beta-adrenoceptor blocking agents on pulsatile ocular blood flow.
    Eye (London, England), 1995, Volume: 9 ( Pt 3)

    Topics: Adrenergic beta-Antagonists; Betaxolol; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Levobunolol; Male; Middle Aged; Ocular Hypertension; Pulsatile Flow; Time Factors; Timolol

1995
Effects of ocular carteolol and timolol on plasma high-density lipoprotein cholesterol level.
    American journal of ophthalmology, 1993, Nov-15, Volume: 116, Issue:5

    Topics: Administration, Topical; Adult; Carteolol; Cholesterol; Cholesterol, HDL; Double-Blind Method; Eye; Humans; Intraocular Pressure; Lipids; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Timolol

1993
A comparison of the ocular tolerability of a single dose of timolol and levobunolol in healthy normotensive volunteers.
    Annals of ophthalmology, 1993, Volume: 25, Issue:4

    Topics: Adult; Aged; Asthenopia; Double-Blind Method; Drug Tolerance; Eye; Female; Humans; Intraocular Pressure; Levobunolol; Male; Middle Aged; Timolol; Vision Disorders

1993
The effect of 0.5% timolol maleate on the ocular perfusion of ocular hypertensive patients by scanning laser flowmetry.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1997, Volume: 13, Issue:3

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Blood Volume; Eye; Female; Humans; Male; Ocular Hypertension; Regional Blood Flow; Timolol

1997
Effect of timolol and UF-021 (a prostaglandin-related compound) on pulsatile ocular blood flow in normal volunteers.
    Ophthalmic research, 1997, Volume: 29, Issue:3

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Blood Pressure; Dinoprost; Double-Blind Method; Eye; Heart Rate; Humans; Intraocular Pressure; Ophthalmic Solutions; Pulsatile Flow; Reference Values; Reproducibility of Results; Timolol

1997
Primary open-angle glaucoma patients characterized by ocular vasospasm demonstrate a different ocular vascular response to timolol versus betaxolol.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1999, Volume: 15, Issue:6

    Topics: Adrenergic beta-Antagonists; Betaxolol; Cross-Over Studies; Double-Blind Method; Eye; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Hypercapnia; Intraocular Pressure; Male; Middle Aged; Ophthalmic Artery; Spasm; Timolol; Ultrasonography, Doppler, Color; Vascular Resistance

1999
[Ocular pulse amplitude, intraocular pressure and beta blocker/carbonic anhydrase inhibition in combined therapy of primary open-angle glaucoma].
    Klinische Monatsblatter fur Augenheilkunde, 1999, Volume: 215, Issue:6

    Topics: Adrenergic beta-Antagonists; Aged; Blood Pressure; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Pulsatile Flow; Sulfonamides; Thiophenes; Timolol

1999
Effect of dorzolamide timolol combination versus timolol 0.5% on ocular bloodflow in patients with primary open-angle glaucoma.
    American journal of ophthalmology, 2001, Volume: 132, Issue:4

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Flow Velocity; Ciliary Arteries; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Eye; Fluorescein Angiography; Glaucoma, Open-Angle; Humans; Indocyanine Green; Intraocular Pressure; Laser-Doppler Flowmetry; Ophthalmic Artery; Ophthalmic Solutions; Ophthalmoscopy; Regional Blood Flow; Retinal Artery; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Ultrasonography; Visual Acuity

2001
Systemic bioavailability and cardiopulmonary effects of 0.5% timolol eyedrops.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2002, Volume: 240, Issue:6

    Topics: Absorption; Adrenergic beta-Antagonists; Adult; Area Under Curve; Biological Availability; Blood Pressure; Cross-Over Studies; Eye; Female; Forced Expiratory Volume; Heart Rate; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Timolol; Vital Capacity

2002
Effect of changing from concomitant timolol pilocarpine to bimatoprost monotherapy on ocular blood flow and IOP in primary chronic angle closure glaucoma.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2003, Volume: 19, Issue:2

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Amides; Bimatoprost; Chronic Disease; Cloprostenol; Drug Therapy, Combination; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lipids; Male; Middle Aged; Pilocarpine; Prospective Studies; Pulsatile Flow; Regional Blood Flow; Single-Blind Method; Timolol; Treatment Outcome

2003
A comparison of the effects of dorzolamide/timolol fixed combination versus latanoprost on intraocular pressure and pulsatile ocular blood flow in primary open-angle glaucoma patients.
    Acta ophthalmologica Scandinavica, 2004, Volume: 82, Issue:6

    Topics: Adult; Aged; Antihypertensive Agents; Blood Flow Velocity; Cross-Over Studies; Drug Therapy, Combination; Eye; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Prostaglandins F, Synthetic; Pulsatile Flow; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Ultrasonography, Doppler

2004
Effect of dorzolamide and timolol on ocular blood flow in patients with primary open angle glaucoma and ocular hypertension.
    The British journal of ophthalmology, 2005, Volume: 89, Issue:10

    Topics: Aged; Antihypertensive Agents; Choroid; Double-Blind Method; Eye; Female; Glaucoma, Open-Angle; Heart Rate; Hemodynamics; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Ocular Hypertension; Optic Disk; Regional Blood Flow; Regression Analysis; Retinal Vessels; Sulfonamides; Thiophenes; Timolol

2005
A comparison of the effects of 0.005% latanoprost and fixed combination dorzolamide/timolol on retrobulbar haemodynamics in previously untreated glaucoma patients.
    Current medical research and opinion, 2006, Volume: 22, Issue:1

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Prostaglandins F, Synthetic; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol; Treatment Outcome

2006
A comparative analysis of the effects of the fixed combination of timolol and dorzolamide versus latanoprost plus timolol on ocular hemodynamics and visual function in patients with primary open-angle glaucoma.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2006, Volume: 22, Issue:5

    Topics: Adrenergic beta-Antagonists; Aged; Blood Pressure; Cross-Over Studies; Double-Blind Method; Eye; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol; Visual Acuity

2006
Efficacy and safety of latanoprost versus pilocarpine/timolol maleate fixed combination in patients with primary open-angle glaucoma or ocular hypertension.
    Acta ophthalmologica, 2008, Volume: 86, Issue:8

    Topics: Aged; Drug Administration Schedule; Drug Combinations; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Pain; Pilocarpine; Prostaglandins F, Synthetic; Timolol; Treatment Outcome; Vision Disorders

2008
24-hour intraocular pressure and blood pressure levels with latanoprost/timolol fixed combination versus timolol.
    Current eye research, 2009, Volume: 34, Issue:5

    Topics: Aged; Blood Pressure; Circadian Rhythm; Cross-Over Studies; Drug Administration Schedule; Drug Combinations; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol

2009
Ocular blood flow and oxygen delivery to the retina in primary open-angle glaucoma patients: the addition of dorzolamide to timolol monotherapy.
    Acta ophthalmologica, 2010, Volume: 88, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Eye; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Middle Aged; Oximetry; Oxygen; Regional Blood Flow; Retina; Retinal Vessels; Sulfonamides; Thiophenes; Timolol; Ultrasonography, Doppler, Color

2010
[Evaluation of the effect of bimatoprost/timolol fixed combination on ocular blood flow in patients with ocular hypertension using colour Doppler imaging. Preliminary study].
    Archivos de la Sociedad Espanola de Oftalmologia, 2010, Volume: 85, Issue:4

    Topics: Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Double-Blind Method; Drug Combinations; Eye; Female; Humans; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Regional Blood Flow; Timolol; Ultrasonography, Doppler, Color

2010
Short-term effects of brimonidine/timolol and dorzolamide/timolol on ocular perfusion pressure and blood flow in glaucoma.
    Advances in therapy, 2012, Volume: 29, Issue:1

    Topics: Administration, Ophthalmic; Aged; Antihypertensive Agents; Blood Pressure; Brimonidine Tartrate; Cross-Over Studies; Double-Blind Method; Drug Combinations; Eye; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Male; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular

2012
A double-masked randomized crossover study comparing the effect of latanoprost/timolol and brimonidine/timolol fixed combination on intraocular pressure and ocular blood flow in patients with primary open-angle glaucoma or ocular hypertension.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2012, Volume: 28, Issue:6

    Topics: Aged; Antihypertensive Agents; Blood Flow Velocity; Brimonidine Tartrate; Cross-Over Studies; Double-Blind Method; Drug Combinations; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Quinoxalines; Time Factors; Timolol; Ultrasonography, Doppler, Color

2012
Effects of dorzolamide-timolol and brimonidine-timolol on retinal vascular autoregulation and ocular perfusion pressure in primary open angle glaucoma.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2013, Volume: 29, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Cross-Over Studies; Drug Combinations; Eye; Female; Glaucoma, Open-Angle; Homeostasis; Humans; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Quinoxalines; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol

2013
Ocular surface evaluation in patients treated with a fixed combination of prostaglandin analogues with 0.5% timolol maleate topical monotherapy: a randomized clinical trial.
    Clinics (Sao Paulo, Brazil), 2013, Volume: 68, Issue:10

    Topics: Aged; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Drug Combinations; Eye; Female; Glaucoma, Open-Angle; HLA-DR Antigens; Humans; Immunohistochemistry; Interleukin-6; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Prostaglandins, Synthetic; Single-Blind Method; Timolol; Travoprost; Treatment Outcome

2013
Preventive Dorzolamide-Timolol for Rising Intraocular Pressure During Steep Trendelenburg Position Surgery.
    AANA journal, 2016, Volume: 84, Issue:3

    Topics: Adult; Aged; Blood Pressure; Double-Blind Method; Drug Combinations; Eye; Female; Head-Down Tilt; Humans; Intraocular Pressure; Intraoperative Complications; Laparoscopy; Male; Middle Aged; Monitoring, Intraoperative; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular

2016

Other Studies

108 other study(ies) available for timolol and eye

ArticleYear
[Experimental studies with timolol: a new ocular hypotensive agent (author's transl)].
    Journal francais d'ophtalmologie, 1978, Volume: 1, Issue:12

    Topics: Animals; Aqueous Humor; Eye; Intraocular Pressure; Propanolamines; Rabbits; Timolol

1978
Increased sensitivity of the non-human primate eye to microwave radiation following ophthalmic drug pretreatment.
    Bioelectromagnetics, 1992, Volume: 13, Issue:5

    Topics: Administration, Topical; Animals; Capillary Permeability; Endothelium, Corneal; Eye; Fluorescein Angiography; Iris; Macaca fascicularis; Macaca mulatta; Microwaves; Pilocarpine; Timolol

1992
Light-dark variations in ocular timolol concentrations following topical solution instillation in the pigmented rabbit.
    Life sciences, 1992, Volume: 51, Issue:26

    Topics: Absorption; Animals; Anterior Eye Segment; Chromatography, High Pressure Liquid; Conjunctiva; Dark Adaptation; Eye; Light; Male; Ophthalmic Solutions; Pigmentation; Rabbits; Sclera; Timolol; Uvea

1992
Duration and long-term efficacy of phenylephrine-induced reduction in the systemic absorption of ophthalmic timolol in rabbits.
    Journal of ocular pharmacology, 1992,Summer, Volume: 8, Issue:2

    Topics: Absorption; Animals; Conjunctiva; Eye; Female; Longitudinal Studies; Male; Nasal Mucosa; Ophthalmic Solutions; Phenylephrine; Rabbits; Timolol; Vasoconstriction

1992
[Effects of timolol and carteolol on ocular pulsatile blood flow].
    Nippon Ganka Gakkai zasshi, 1992, Volume: 96, Issue:8

    Topics: Adult; Carteolol; Eye; Humans; Intraocular Pressure; Pulsatile Flow; Regional Blood Flow; Timolol

1992
Effects of timolol, betaxolol, and levobunolol on human tenon's fibroblasts in tissue culture.
    Investigative ophthalmology & visual science, 1992, Volume: 33, Issue:7

    Topics: Benzalkonium Compounds; Betaxolol; Cell Adhesion; Cell Division; Cells, Cultured; DNA Replication; Eye; Fascia; Fibroblasts; Humans; Levobunolol; Timolol

1992
Improving the safety of topically applied timolol in the pigmented rabbit through manipulation of formulation composition.
    Experimental eye research, 1992, Volume: 54, Issue:5

    Topics: Administration, Topical; Animals; Chromatography, High Pressure Liquid; Drug Delivery Systems; Eye; Hydrogen-Ion Concentration; Male; Polymers; Rabbits; Timolol

1992
Effect of nasolacrimal occlusion on timolol concentrations in the aqueous humor of the human eye.
    Journal of pharmaceutical sciences, 1992, Volume: 81, Issue:3

    Topics: Aged; Aged, 80 and over; Aqueous Humor; Cataract Extraction; Eye; Female; Humans; Male; Middle Aged; Nasolacrimal Duct; Timolol

1992
The effects of glaucoma medications on Tenon's capsule and conjunctiva in the rabbit.
    Ophthalmic surgery, 1991, Volume: 22, Issue:6

    Topics: Administration, Topical; Animals; Antihypertensive Agents; Conjunctiva; Disease Models, Animal; Epinephrine; Eye; Fascia; Glaucoma; Pilocarpine; Pilot Projects; Rabbits; Timolol

1991
Postural studies in pulsatile ocular blood flow: II. Chronic open angle glaucoma.
    The British journal of ophthalmology, 1991, Volume: 75, Issue:2

    Topics: Adult; Aged; Blood Pressure; Chronic Disease; Eye; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Posture; Pulsatile Flow; Supination; Time Factors; Timolol

1991
Ocular drug interactions involving topically applied timolol in the pigmented rabbit.
    Current eye research, 1991, Volume: 10, Issue:3

    Topics: Absorption; Animals; Drug Interactions; Epinephrine; Eye; Male; Ophthalmic Solutions; Pilocarpine; Rabbits; Timolol

1991
Effects of D-timolol and L-timolol on ocular blood flow and intraocular pressure.
    Journal of ocular pharmacology, 1990,Spring, Volume: 6, Issue:1

    Topics: Administration, Topical; Animals; Choroid; Eye; Female; Injections, Intravenous; Intraocular Pressure; Male; Rabbits; Regional Blood Flow; Retinal Vessels; Stereoisomerism; Timolol

1990
Trifluridine decreases ocular HSV-1 recovery, but not herpetic lesions after timolol iontophoresis.
    Investigative ophthalmology & visual science, 1989, Volume: 30, Issue:4

    Topics: Animals; Eye; Iontophoresis; Keratitis, Dendritic; Rabbits; Simplexvirus; Thymidine; Timolol; Trifluridine

1989
Microvascular access to the uveal tract in the rabbit eye for ocular pharmacologic studies.
    Ophthalmic research, 1989, Volume: 21, Issue:6

    Topics: Animals; Catheterization, Peripheral; Dose-Response Relationship, Drug; Eye; Insulin; Intraocular Pressure; Microcirculation; Pharmaceutical Preparations; Pilocarpine; Rabbits; Timolol; Uvea

1989
Effects of stimulation of the ocular sympathetic nerves on IOP and aqueous humor flow.
    Investigative ophthalmology & visual science, 1987, Volume: 28, Issue:10

    Topics: Animals; Anterior Chamber; Aqueous Humor; Electric Stimulation; Eye; Female; Intraocular Pressure; Male; Phentolamine; Rabbits; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sympathetic Nervous System; Timolol

1987
[Kinetics of drugs in ophthalmology].
    Bulletin des societes d'ophtalmologie de France, 1985, Volume: Spec No

    Topics: Adrenal Cortex Hormones; Adrenergic beta-Antagonists; Animals; Anti-Bacterial Agents; Eye; Eye Diseases; Humans; Kinetics; Ophthalmic Solutions; Pharmaceutical Preparations; Timolol; Tissue Distribution

1985
Topical timolol, at conventional, unilateral doses causes bilateral ocular beta-blockade in rabbits.
    Experimental eye research, 1987, Volume: 44, Issue:2

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Blood Pressure; Dose-Response Relationship, Drug; Eye; Female; Heart Rate; Intraocular Pressure; Isoproterenol; Male; Rabbits; Time Factors; Timolol

1987
Tolerability of timolol and betaxolol in patients with chronic open-angle glaucoma.
    Clinical therapeutics, 1987, Volume: 9, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Betaxolol; Chronic Disease; Drug Tolerance; Eye; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ophthalmic Solutions; Propanolamines; Timolol

1987
Ocular and cardiac beta-antagonism by timolol prodrugs, timolol and levobunolol.
    Current eye research, 1988, Volume: 7, Issue:8

    Topics: Adrenergic beta-Antagonists; Animals; Eye; Heart; Heart Rate; Intraocular Pressure; Isoproterenol; Levobunolol; Male; Prodrugs; Rabbits; Timolol

1988
Peripheral adrenergic stimulation and indomethacin in experimental ocular shedding of HSV.
    Current eye research, 1987, Volume: 6, Issue:1

    Topics: Animals; Eye; Hydroxydopamines; Indomethacin; Keratitis, Dendritic; Oxidopamine; Rabbits; Simplexvirus; Stimulation, Chemical; Sympathomimetics; Timolol

1987
Timolol promotes reactivation of latent HSV-1 in the mouse iontophoresis model.
    Investigative ophthalmology & visual science, 1987, Volume: 28, Issue:3

    Topics: Animals; Eye; Ganglia; Iontophoresis; Male; Mice; Mice, Inbred BALB C; Reaction Time; Simplexvirus; Timolol; Trigeminal Nerve; Virus Activation

1987
Timolol induces HSV-1 ocular shedding in the latently infected rabbit.
    Investigative ophthalmology & visual science, 1987, Volume: 28, Issue:3

    Topics: Administration, Topical; Animals; Eye; Iontophoresis; Keratitis, Dendritic; Rabbits; Simplexvirus; Timolol

1987
Timolol binding to bovine ocular melanin in vitro.
    Journal of ocular pharmacology, 1988,Spring, Volume: 4, Issue:1

    Topics: Animals; Binding, Competitive; Cattle; Ethanol; Eye; Hydrogen-Ion Concentration; In Vitro Techniques; Iris; Kinetics; Melanins; Propranolol; Stereoisomerism; Timolol

1988
Ocular hypotensive effects of monoamine oxidase-A inhibitors in rabbit.
    Japanese journal of ophthalmology, 1988, Volume: 32, Issue:2

    Topics: Animals; Drug Synergism; Epinephrine; Eye; Intraocular Pressure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pupil; Rabbits; Time Factors; Timolol; Tissue Distribution

1988
Application site dependent ocular absorption of timolol.
    Journal of ocular pharmacology, 1988,Winter, Volume: 4, Issue:4

    Topics: Absorption; Administration, Topical; Animals; Ciliary Body; Conjunctiva; Cornea; Drug Administration Routes; Eye; Iris; Rabbits; Sclera; Timolol; Vitreous Body

1988
Regional ocular blood flow after chronic topical glaucoma drug treatment.
    Acta ophthalmologica, 1987, Volume: 65, Issue:4

    Topics: Animals; Drug Evaluation, Preclinical; Echothiophate Iodide; Epinephrine; Eye; Glaucoma; Microspheres; Norepinephrine; Pilocarpine; Rabbits; Regional Blood Flow; Timolol

1987
Bilateral effects of monocular timolol treatment.
    American journal of ophthalmology, 1986, Aug-15, Volume: 102, Issue:2

    Topics: Eye; Humans; Intraocular Pressure; Male; Middle Aged; Timolol

1986
Effects of antiglaucoma drugs on the blood flow in rabbit eyes.
    Ophthalmic research, 1986, Volume: 18, Issue:5

    Topics: Animals; Blood Flow Velocity; Butyrophenones; Drug Evaluation, Preclinical; Eye; Glaucoma; Haloperidol; Intraocular Pressure; Pilocarpine; Rabbits; Timolol; Trifluperidol

1986
Lack of metabolism of timolol by ocular tissues.
    Journal of ocular pharmacology, 1985,Fall, Volume: 1, Issue:3

    Topics: Animals; Chromatography, High Pressure Liquid; Culture Techniques; Eye; Liver; Macaca fascicularis; Rabbits; Timolol

1985
Attempt to arrest eye growth by means of ocular hypotony.
    Metabolic, pediatric, and systemic ophthalmology (New York, N.Y. : 1985), 1985, Volume: 8, Issue:4

    Topics: Animals; Eye; Intraocular Pressure; Timolol; Ultrasonography

1985
Potential systemic and ocular side effects associated with topical administration of timolol maleate.
    Journal of the American Optometric Association, 1985, Volume: 56, Issue:2

    Topics: Eye; Humans; Ophthalmic Solutions; Timolol

1985
[A study of arterially perfused enucleated eye--drug effects on aqueous humor formation].
    Nippon Ganka Gakkai zasshi, 1985, Volume: 89, Issue:2

    Topics: Acetazolamide; Animals; Aqueous Humor; Epinephrine; Eye; In Vitro Techniques; Organ Preservation; Ouabain; Perfusion; Pilocarpine; Rabbits; Timolol

1985
Blood flow in aphakic rabbit eyes after sub-chronic glaucoma drug treatment.
    Current eye research, 1985, Volume: 4, Issue:6

    Topics: Animals; Aphakia; Choroid; Ciliary Body; Echothiophate Iodide; Epinephrine; Eye; Intraocular Pressure; Iris; Norepinephrine; Optic Nerve; Pilocarpine; Rabbits; Regional Blood Flow; Retinal Vessels; Timolol

1985
Timolol and pilocarpine are hypotensive in light-induced avian glaucoma.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1985, Volume: 20, Issue:4

    Topics: Animals; Aqueous Humor; Chickens; Eye; Glaucoma; Injections, Intravenous; Intraocular Pressure; Light; Pilocarpine; Radiation Injuries, Experimental; Timolol

1985
Ocular penetration of beta-adrenergic blocking agents. An experimental study with atenolol, metoprolol, timolol and propranolol.
    Documenta ophthalmologica. Advances in ophthalmology, 1980, Apr-15, Volume: 48, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Aqueous Humor; Atenolol; Carbon Radioisotopes; Ciliary Body; Cornea; Eye; Female; Iris; Male; Metoprolol; Nictitating Membrane; Propranolol; Rabbits; Timolol; Tritium

1980
Pharmacological effects of topical timolol in the rabbit eye.
    Investigative ophthalmology & visual science, 1980, Volume: 19, Issue:10

    Topics: Adrenergic beta-Antagonists; Animals; Ciliary Body; Cyclic AMP; Eye; In Vitro Techniques; Intraocular Pressure; Iris; Isoproterenol; Propanolamines; Rabbits; Timolol

1980
Effects of selective beta 1- and beta 2-adrenoreceptor agonists and antagonists on intraocular pressure in the cat.
    Investigative ophthalmology & visual science, 1981, Volume: 20, Issue:1

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Atenolol; Carbachol; Cats; Dose-Response Relationship, Drug; Echothiophate Iodide; Eye; Female; Intraocular Pressure; Male; Sympathectomy; Timolol

1981
The effect of timolol maleate on the disruption of the blood-aqueous barrier in the rabbit eye.
    Investigative ophthalmology & visual science, 1981, Volume: 20, Issue:6

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Aqueous Humor; Eye; Melanocyte-Stimulating Hormones; Propanolamines; Prostaglandins E; Rabbits; Timolol

1981
The effect of beta blocking drugs and carboxyanhydrase inhibitors on the standing potential of the eye.
    Bulletin de la Societe belge d'ophtalmologie, 1980, Volume: 191

    Topics: Acetazolamide; Action Potentials; Adrenergic beta-Antagonists; Adult; Carbonic Anhydrase Inhibitors; Electrooculography; Eye; Humans; Timolol

1980
Beta-adrenergic blockers: ocular penetration and binding to the uveal pigment.
    Japanese journal of ophthalmology, 1982, Volume: 26, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Aqueous Humor; Cornea; Eye; Permeability; Pigment Epithelium of Eye; Propanolamines; Rabbits; Time Factors; Timolol; Uvea

1982
[A preliminary study of effects of beta-blockers and benzalkonium chloride on pigmented rabbit's eye; electrophysiological and morphological studies].
    Nippon Ganka Gakkai zasshi, 1983, Mar-10, Volume: 87, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Benzalkonium Compounds; Electroretinography; Eye; Female; Male; Preservatives, Pharmaceutical; Propanolamines; Rabbits; Retinal Pigments; Timolol

1983
Filtering valve implant for neovascular glaucoma in proliferative diabetic retinopathy.
    Ophthalmology, 1982, Volume: 89, Issue:3

    Topics: Adult; Cryosurgery; Diabetic Retinopathy; Equipment Failure; Eye; Female; Filtration; Glaucoma; Humans; Intraocular Pressure; Laser Therapy; Lasers; Neovascularization, Pathologic; Timolol

1982
Topical timolol and epinephrine: biochemical actions and interactions in the rabbit eye in vivo.
    Annals of ophthalmology, 1983, Volume: 15, Issue:2

    Topics: Administration, Topical; Animals; Aqueous Humor; Cyclic AMP; Drug Combinations; Epinephrine; Eye; Propanolamines; Rabbits; Timolol

1983
Effect of topical epinephrine and timolol on ocular and optic nerve blood flow in phakic and aphakic rabbit eyes.
    Current eye research, 1984, Volume: 3, Issue:10

    Topics: Animals; Aphakia; Choroid; Ciliary Body; Epinephrine; Eye; Female; Intraocular Pressure; Iris; Male; Optic Nerve; Rabbits; Regional Blood Flow; Retinal Vessels; Timolol

1984
Effects of timolol on intraocular pressure following ocular adrenergic denervation.
    Current eye research, 1984, Volume: 3, Issue:9

    Topics: Animals; Eye; Ganglia, Sympathetic; Intraocular Pressure; Rabbits; Receptors, Adrenergic; Timolol

1984
The treatment of acute angle-closure glaucoma revisited.
    Annals of ophthalmology, 1984, Volume: 16, Issue:12

    Topics: Acetazolamide; Acute Disease; Aged; Drug Therapy, Combination; Eye; Glaucoma; Humans; Middle Aged; Pilocarpine; Timolol

1984
Side effects of timolol.
    Survey of ophthalmology, 1983, Volume: 28 Suppl

    Topics: Administration, Topical; Cardiovascular System; Central Nervous System; Eye; Humans; Respiration; Timolol

1983
Safe use of ocular drugs in the elderly.
    Geriatrics, 1984, Volume: 39, Issue:4

    Topics: Adrenal Cortex Hormones; Aged; Anesthetics, Local; Epinephrine; Eye; Humans; Ophthalmic Solutions; Parasympatholytics; Phenylephrine; Thimerosal; Timolol

1984
Disposition of ophthalmic timolol in treated and untreated rabbit eyes. A multiple and single dose study.
    Experimental eye research, 1984, Volume: 38, Issue:2

    Topics: Albinism; Animals; Eye; Ophthalmic Solutions; Rabbits; Timolol; Tissue Distribution

1984
The effect of d-timolol on intraocular pressure in patients with ocular hypertension.
    American journal of ophthalmology, 1984, Jul-15, Volume: 98, Issue:1

    Topics: Administration, Topical; Adult; Aged; Blood Pressure; Double-Blind Method; Drug Evaluation; Eye; Female; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pupil; Random Allocation; Stereoisomerism; Timolol; Visual Acuity

1984
[Timolol effects in the rabbit eye (author's transl)].
    Ceskoslovenska oftalmologie, 1982, Volume: 38, Issue:2

    Topics: Animals; Eye; Intraocular Pressure; Propanolamines; Rabbits; Timolol

1982
[Timolol maleate: pharmacokinetic analysis of ocular penetration in the rabbit eye and effects on human aqueous humor dynamics (author's transl)].
    Nippon Ganka Gakkai zasshi, 1980, Dec-10, Volume: 84, Issue:12

    Topics: Adult; Animals; Aqueous Humor; Eye; Humans; Male; Ophthalmic Solutions; Propanolamines; Rabbits; Timolol

1980
Effect of timolol maleate on intraocular pressure and pupil cycle time in normal eyes.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1981, Volume: 16, Issue:3

    Topics: Administration, Topical; Adult; Drug Administration Schedule; Eye; Humans; Intraocular Pressure; Maleates; Propanolamines; Reflex, Pupillary; Timolol

1981
Penetration of timolol into the rabbit eye. Measurements after ocular instillation and intravenous injection.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1980, Volume: 98, Issue:3

    Topics: Administration, Topical; Animals; Aqueous Humor; Carbon Radioisotopes; Chromatography, Gas; Eye; Injections, Intravenous; Propanolamines; Rabbits; Scintillation Counting; Time Factors; Timolol; Tissue Distribution

1980
The effect of topical beta-blocker medications on the proliferation and viability of human Tenon's capsule fibroblasts in tissue culture.
    German journal of ophthalmology, 1995, Volume: 4, Issue:3

    Topics: Adrenergic beta-Antagonists; Benzalkonium Compounds; Carteolol; Cell Division; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Eye; Fascia; Fibroblasts; Humans; Levobunolol; Ophthalmic Solutions; Timolol

1995
Plasma kinetics and antagonist activity of topical ocular timolol in elderly patients.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1995, Volume: 233, Issue:3

    Topics: Absorption; Administration, Topical; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Aged; Aged, 80 and over; Cataract Extraction; Eye; Humans; Lenses, Intraocular; Middle Aged; Ophthalmic Solutions; Radioligand Assay; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Timolol

1995
Controlled ocular timolol delivery: systemic absorption and intraocular pressure effects in humans.
    Pharmaceutical research, 1994, Volume: 11, Issue:9

    Topics: Absorption; Aged; Drug Delivery Systems; Eye; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Silicones; Timolol

1994
Ocular timolol levels after drug withdrawal: an experimental model.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1994, Volume: 29, Issue:5

    Topics: Animals; Aqueous Humor; Eye; Melanins; Models, Biological; Ophthalmic Solutions; Pigment Epithelium of Eye; Rabbits; Timolol; Tissue Distribution; Uvea

1994
Systemic absorption pathways of topically applied beta adrenergic antagonists in the pigmented rabbit.
    Experimental eye research, 1993, Volume: 57, Issue:3

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Atenolol; Betaxolol; Biological Availability; Conjunctiva; Eye; Levobunolol; Male; Nasal Mucosa; Nasolacrimal Duct; Rabbits; Time Factors; Timolol

1993
Influence of drug release rate on systemic timolol absorption from polymeric ocular inserts in the pigmented rabbit.
    Journal of ocular pharmacology, 1994,Summer, Volume: 10, Issue:2

    Topics: Absorption; Animals; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Drug Carriers; Eye; Eyelids; Male; Polymers; Rabbits; Suppositories; Timolol

1994
The effect of topical pilocarpine on pulsatile ocular blood flow.
    Eye (London, England), 1993, Volume: 7 ( Pt 4)

    Topics: Administration, Topical; Aged; Drug Therapy, Combination; Eye; Glaucoma, Open-Angle; Humans; Middle Aged; Pilocarpine; Pulsatile Flow; Regional Blood Flow; Timolol

1993
Drug effects on intraocular pressure and vascular flow in the bovine perfused eye using radiolabelled microspheres.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1995,Spring, Volume: 11, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Blood Flow Velocity; Carteolol; Cattle; Cerium Radioisotopes; Choroid; Ciliary Body; Eye; Intraocular Pressure; Iris; Microspheres; Nitroprusside; Perfusion; Regional Blood Flow; Timolol; Vasodilator Agents; Verapamil

1995
Comparison of concentration-time profiles of levobunolol and timolol in anterior and posterior ocular tissues of albino rabbits.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1995,Winter, Volume: 11, Issue:4

    Topics: Absorption; Adrenergic beta-Antagonists; Animals; Aqueous Humor; Biological Availability; Choroid; Ciliary Body; Eye; Female; Gas Chromatography-Mass Spectrometry; Half-Life; Iris; Levobunolol; Ophthalmic Solutions; Optic Nerve; Rabbits; Retina; Timolol; Tissue Distribution; Vitreous Body

1995
Vaninolol: a novel compound for the treatment of glaucoma and ischemic retinopathy.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1995,Fall, Volume: 11, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Blood Flow Velocity; Butanones; Electroretinography; Eye; Female; Glaucoma; Intraocular Pressure; Ischemia; Male; Microspheres; Ocular Hypertension; Propanolamines; Rabbits; Rats; Retina; Retinal Artery; Retinal Artery Occlusion; Timolol

1995
Pharmacokinetic differences between ocular inserts and eyedrops.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1996,Spring, Volume: 12, Issue:1

    Topics: Absorption; Animals; Delayed-Action Preparations; Eye; Male; Models, Biological; Ophthalmic Solutions; Rabbits; Timolol

1996
Effects of pilocarpine and other antiglaucoma drugs on cultured human Tenon's fibroblast cells.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1997, Volume: 13, Issue:1

    Topics: Adrenergic beta-Antagonists; Betaxolol; Carteolol; Cell Division; Cells, Cultured; Eye; Fibroblasts; Glaucoma; Humans; Levobunolol; Muscarinic Agonists; Pilocarpine; Thymidine; Timolol

1997
[Ophthalmic mucoadhesive vehicles: preliminary study of ocular pharmacokinetics "in vivo"].
    Bollettino chimico farmaceutico, 1996, Volume: 135, Issue:2

    Topics: Adhesiveness; Adrenergic beta-Antagonists; Animals; Eye; Mucous Membrane; Ophthalmic Solutions; Polymers; Rabbits; Timolol

1996
In-situ ocular absorption of ophthalmic beta-blockers through ocular membranes in albino rabbits.
    The Journal of pharmacy and pharmacology, 1997, Volume: 49, Issue:2

    Topics: Absorption; Adrenergic beta-Antagonists; Animals; Carteolol; Conjunctiva; Cornea; Eye; Male; Propanolamines; Rabbits; Sclera; Timolol

1997
Ocular-specific delivery of timolol by sequential bioactivation of its oxime and methoxime analogs.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1997, Volume: 13, Issue:5

    Topics: Administration, Topical; Adrenergic beta-Agonists; Animals; Eye; Hydrolysis; Intraocular Pressure; Isoproterenol; Kinetics; Male; Rabbits; Rats; Rats, Sprague-Dawley; Tachycardia; Timolol

1997
Bioavailability of timolol and aceclidine after ocular instillation in the rabbit.
    Research communications in molecular pathology and pharmacology, 1998, Volume: 100, Issue:1

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Aqueous Humor; Area Under Curve; Biological Availability; Eye; Half-Life; Male; Parasympathomimetics; Pupil; Quinuclidines; Rabbits; Spectrophotometry, Ultraviolet; Timolol

1998
Discoidal niosome based controlled ocular delivery of timolol maleate.
    Die Pharmazie, 1998, Volume: 53, Issue:7

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Delayed-Action Preparations; Drug Delivery Systems; Eye; Female; Hydrogen-Ion Concentration; Intraocular Pressure; Male; Micelles; Polyethylene Glycols; Rabbits; Surface-Active Agents; Timolol

1998
Characterization of ocular pharmacokinetics of beta-blockers using a diffusion model after instillation.
    Pharmaceutical research, 1999, Volume: 16, Issue:10

    Topics: Absorption; Administration, Topical; Adrenergic beta-Antagonists; Algorithms; Animals; Anterior Chamber; Aqueous Humor; Cornea; Dextrans; Diffusion; Eye; Fluorescein-5-isothiocyanate; Isoquinolines; Models, Biological; Rabbits; Timolol

1999
Drug release from cation exchange membrane in rabbit eye.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1999, Volume: 15, Issue:6

    Topics: Acrylic Resins; Adsorption; Animals; Cations; Chromatography, High Pressure Liquid; Conjunctiva; Eye; Ion Exchange; Male; Membranes, Artificial; Osmolar Concentration; Polyvinyls; Propranolol; Rabbits; Timolol

1999
Short-term effect of beta-adrenoreceptor blocking agents on ocular blood flow.
    Current eye research, 2001, Volume: 23, Issue:4

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Betaxolol; Blood Flow Velocity; Blood Pressure; Carteolol; Choroid; Ciliary Body; Eye; Heart Rate; Intraocular Pressure; Rabbits; Random Allocation; Regional Blood Flow; Retinal Vessels; Timolol; Vascular Resistance

2001
[The effect of three kinds of anti-glaucoma eyedrops on ocular blood flow].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2000, Volume: 36, Issue:6

    Topics: Adult; Aged; Epinephrine; Eye; Female; Fluorescein Angiography; Glaucoma; Humans; Levobunolol; Male; Middle Aged; Ophthalmic Solutions; Regional Blood Flow; Timolol

2000
Effects of a beta-adrenergic blocking agent timolol on intra ocular pressure responses induced by stimulation of cervical sympathetic nerve in the cat.
    The Tohoku journal of experimental medicine, 2001, Volume: 195, Issue:4

    Topics: Adrenergic beta-Antagonists; Adrenergic Fibers; Animals; Cats; Cervical Vertebrae; Electric Stimulation; Eye; Intraocular Pressure; Timolol

2001
Timolol concentrations in rat ocular tissues and plasma after topical and intraperitoneal dosing.
    Journal of glaucoma, 2002, Volume: 11, Issue:2

    Topics: Absorption; Administration, Topical; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Biological Availability; Chromatography, High Pressure Liquid; Eye; Injections, Intraperitoneal; Intraocular Pressure; Rats; Rats, Long-Evans; Timolol; Tissue Distribution

2002
Bioavailability in the human eye of a fixed combination of latanoprost and timolol compared to monotherapy.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2002, Volume: 18, Issue:2

    Topics: Absorption; Aged; Aqueous Humor; Biological Availability; Drug Combinations; Eye; Female; Half-Life; Humans; Intraocular Pressure; Latanoprost; Male; Prostaglandins F, Synthetic; Time Factors; Timolol

2002
[Physiologic significance of the interaction between timolol and free amino acids in eye structures].
    Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti, 2002, Volume: 58, Issue:3

    Topics: Adrenergic beta-Antagonists; Amino Acids; Autoradiography; Chromatography, Thin Layer; Eye; Glaucoma, Open-Angle; Timolol

2002
The pulsatile ocular blood flow behaviour in open angle glaucoma patients after replacing timolol therapy with timolol and dorzolamide fixed combination: preliminary study.
    Acta ophthalmologica Scandinavica. Supplement, 2002, Volume: 236

    Topics: Adrenergic beta-Antagonists; Aged; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Pulsatile Flow; Sulfonamides; Thiophenes; Timolol

2002
[Glaucoma: an ocular blood flow disorder?].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2003, Volume: 100, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Eye; Female; Glaucoma; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Rheology; Risk Factors; Sulfonamides; Thiophenes; Time Factors; Timolol

2003
Comparison of the effects of topical levobunolol and timolol solution on the human ocular surface.
    Cornea, 2003, Volume: 22, Issue:8

    Topics: Adrenergic beta-Antagonists; Adult; Contrast Media; Cornea; Epithelium, Corneal; Eye; Female; Fluorescein; Humans; Irritants; Levobunolol; Male; Middle Aged; Reference Values; Solutions; Tears; Timolol

2003
Vitamin B2-sensitised photooxidation of the ophthalmic drugs Timolol and Pindolol: kinetics and mechanism.
    Redox report : communications in free radical research, 2004, Volume: 9, Issue:5

    Topics: Adrenergic beta-Antagonists; Animals; Anions; Electrons; Eye; Free Radicals; Kinetics; Light; Models, Chemical; Oxygen; Oxygen Consumption; Photosensitizing Agents; Pindolol; Reactive Oxygen Species; Riboflavin; Spectrophotometry; Time Factors; Timolol; Ultraviolet Rays

2004
Improved pharmacodynamics of timolol maleate from a mucoadhesive niosomal ophthalmic drug delivery system.
    International journal of pharmaceutics, 2005, Feb-16, Volume: 290, Issue:1-2

    Topics: Adhesives; Animals; Drug Delivery Systems; Eye; Liposomes; Male; Ophthalmic Solutions; Rabbits; Timolol

2005
A mathematical model for ocular tear and solute balance.
    Current eye research, 2005, Volume: 30, Issue:10

    Topics: Eye; Homeostasis; Humans; Instillation, Drug; Models, Biological; Ophthalmic Solutions; Osmolar Concentration; Surface Tension; Tears; Timolol

2005
Ocular powder: dry topical formulations of timolol are well tolerated in rabbits.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2006, Volume: 22, Issue:5

    Topics: Animals; Aqueous Humor; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Eye; Feasibility Studies; Female; Male; Powders; Rabbits; Radiography; Reproducibility of Results; Timolol

2006
Resistance to blood flow in the rabbit ophthalmic artery after topical treatment with timolol.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2007, Volume: 23, Issue:2

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Blood Flow Velocity; Blood Pressure; Dose-Response Relationship, Drug; Eye; Heart Rate; Intraocular Pressure; Ophthalmic Artery; Rabbits; Regional Blood Flow; Timolol; Ultrasonography, Doppler, Color

2007
Biodegradable fumarate-based drug-delivery systems for ophthalmic applications.
    Journal of biomedical materials research. Part A, 2009, Mar-15, Volume: 88, Issue:4

    Topics: Acetazolamide; Animals; Antihypertensive Agents; Biocompatible Materials; Carbonic Anhydrase Inhibitors; Chromatography, High Pressure Liquid; Dichlorphenamide; Diuretics; Drug Carriers; Drug Delivery Systems; Eye; Fumarates; Implants, Experimental; Molecular Structure; Polypropylenes; Rabbits; Timolol

2009
Ocular pharmacokinetic/pharmacodynamic modeling for timolol in rabbits using a telemetry system.
    Biological & pharmaceutical bulletin, 2008, Volume: 31, Issue:5

    Topics: Adrenergic beta-Antagonists; Algorithms; Animals; Eye; Injections; Intraocular Pressure; Male; Rabbits; Telemetry; Timolol

2008
The effect of timolol maleate on tear film break-up time in Nigerians.
    African journal of medicine and medical sciences, 2008, Volume: 37, Issue:1

    Topics: Adrenergic beta-Agonists; Adult; Aged; Case-Control Studies; Dry Eye Syndromes; Eye; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Nigeria; Surveys and Questionnaires; Tears; Time Factors; Timolol

2008
Matrix modifications modulate ophthalmic drug delivery from photo-cross-linked poly(propylene fumarate)-based networks.
    Journal of biomaterials science. Polymer edition, 2009, Volume: 20, Issue:1

    Topics: Acetazolamide; Antihypertensive Agents; Diuretics; Drug Administration Routes; Drug Carriers; Drug Delivery Systems; Eye; Fumarates; Molecular Structure; Ophthalmic Solutions; Polyethylene Glycols; Polymers; Polypropylenes; Timolol

2009
Effectiveness of dorzolamide–timolol (COSOPT) in patients who were treatment naive for open-angle glaucoma or ocular hypertension: the COSOPT first-line study.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2010, Volume: 26, Issue:5

    Topics: Aged; Drug Combinations; Eye; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Multicenter Studies as Topic; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome

2010
Time course of changes in ocular aberrations after instillation of carteolol long-acting solution and timolol gel-forming solution.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2011, Volume: 27, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Carteolol; Eye; Female; Gels; Humans; Male; Ophthalmic Solutions; Timolol

2011
Characterization of intraocular pressure responses of the Tibetan monkey (Macaca thibetana).
    Molecular vision, 2011, Volume: 17

    Topics: Animals; Antihypertensive Agents; Circadian Rhythm; Cloprostenol; Eye; Glaucoma; Intraocular Pressure; Macaca; Male; Models, Animal; Naphazoline; Pyrrolidines; Timolol; Tonometry, Ocular; Travoprost

2011
New mucoadhesive chitosan film for ophthalmic drug delivery of timolol maleate: in vivo evaluation.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2012, Volume: 28, Issue:4

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Calorimetry, Differential Scanning; Chitosan; Drug Delivery Systems; Eye; Intraocular Pressure; Male; Ophthalmic Solutions; Rabbits; Solubility; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Timolol; Tissue Adhesives; Water

2012
The effects of a fixed combination of 0.5% timolol and 1% dorzolamide on optic nerve head blood circulation.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2012, Volume: 28, Issue:4

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Blood Pressure; Carbonic Anhydrase Inhibitors; Drug Combinations; Drug Synergism; Eye; Female; Heart Rate; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Optic Disk; Perfusion; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol; Young Adult

2012
Extended drug delivery by contact lenses for glaucoma therapy.
    Journal of controlled release : official journal of the Controlled Release Society, 2012, Aug-20, Volume: 162, Issue:1

    Topics: Animals; Antihypertensive Agents; Contact Lenses, Extended-Wear; Dogs; Drug Delivery Systems; Eye; Glaucoma; Intraocular Pressure; Ophthalmic Solutions; Timolol; Vitamin E

2012
In vivo evaluation and in-depth pharmaceutical characterization of a rapidly dissolving solid ocular matrix for the topical delivery of timolol maleate in the rabbit eye model.
    International journal of pharmaceutics, 2014, May-15, Volume: 466, Issue:1-2

    Topics: Administration, Ophthalmic; Animals; Antihypertensive Agents; Chick Embryo; Chorioallantoic Membrane; Drug Delivery Systems; Eye; In Vitro Techniques; Ophthalmic Solutions; Permeability; Rabbits; Solubility; Timolol

2014
Paroxetine markedly increases plasma concentrations of ophthalmic timolol; CYP2D6 inhibitors may increase the risk of cardiovascular adverse effects of 0.5% timolol eye drops.
    Drug metabolism and disposition: the biological fate of chemicals, 2014, Volume: 42, Issue:12

    Topics: Adult; Area Under Curve; Cardiovascular Diseases; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Drug Interactions; Eye; Heart Rate; Humans; Male; Ophthalmic Solutions; Paroxetine; Risk; Timolol; Young Adult

2014
The transcorneal penetration of commercial ophthalmic formulations containing timolol maleate in rabbit eyes.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2015, Volume: 31, Issue:1

    Topics: Animals; Benzalkonium Compounds; Chromatography, Liquid; Cloprostenol; Cornea; Drug Combinations; Eye; Glaucoma; Male; Ophthalmic Solutions; Preservatives, Pharmaceutical; Prostaglandins F, Synthetic; Rabbits; Sulfonamides; Thiophenes; Timolol

2015
Chitosan derivatives as effective nanocarriers for ocular release of timolol drug.
    International journal of pharmaceutics, 2015, Nov-10, Volume: 495, Issue:1

    Topics: Chemistry, Pharmaceutical; Chitosan; Drug Carriers; Drug Liberation; Eye; Microscopy, Electron, Transmission; Nanoparticles; Particle Size; Polyphosphates; Spectroscopy, Fourier Transform Infrared; Succinic Anhydrides; Timolol; X-Ray Diffraction

2015
Comparison of Ocular Pulse Amplitude Lowering Effects of Preservative-Free Tafluprost and Preservative-Free Dorzolamide-Timolol Fixed Combination Eyedrops.
    BioMed research international, 2015, Volume: 2015

    Topics: Drug Combinations; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Low Tension Glaucoma; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Preservatives, Pharmaceutical; Prostaglandins F; Retrospective Studies; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular

2015
Drug Distribution to Retinal Pigment Epithelium: Studies on Melanin Binding, Cellular Kinetics, and Single Photon Emission Computed Tomography/Computed Tomography Imaging.
    Molecular pharmaceutics, 2016, 09-06, Volume: 13, Issue:9

    Topics: Animals; Cells, Cultured; Chloroquine; Eye; Hydrogen-Ion Concentration; Iodine Radioisotopes; Kinetics; Melanins; Methotrexate; Nadolol; Protein Binding; Rats; Retinal Pigment Epithelium; Single Photon Emission Computed Tomography Computed Tomography; Swine; Timolol

2016
Effects of dorzolamide/timolol fixed combination on retrobulbar hemodynamics in pseudoexfoliative glaucoma.
    The Kaohsiung journal of medical sciences, 2016, Volume: 32, Issue:1

    Topics: Aged; Carbonic Anhydrase Inhibitors; Cross-Sectional Studies; Drug Combinations; Exfoliation Syndrome; Eye; Female; Hemodynamics; Humans; Male; Middle Aged; Prospective Studies; Regional Blood Flow; Retinal Artery; Sulfonamides; Thiophenes; Timolol; Treatment Outcome

2016
Self-Assembling Elastin-Like Hydrogels for Timolol Delivery: Development of an Ophthalmic Formulation Against Glaucoma.
    Molecular pharmaceutics, 2017, 12-04, Volume: 14, Issue:12

    Topics: Animals; Antihypertensive Agents; Calorimetry, Differential Scanning; Cell Line; Drug Carriers; Drug Liberation; Elastin; Eye; Fibroblasts; Glaucoma; Humans; Hydrogels; Intraocular Pressure; Male; Models, Animal; Ophthalmic Solutions; Rabbits; Rheology; Silk; Timolol; Treatment Outcome

2017
Changes in Ocular Hemodynamics after Carotid Artery Angioplasty and Stenting (CAAS) in Patients with Different Severity of Ocular Ischemic Syndrome.
    Current eye research, 2018, Volume: 43, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Angioplasty, Balloon; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Carotid Artery, Internal; Carotid Stenosis; Drug Therapy, Combination; Eye; Female; Humans; Intraocular Pressure; Iris; Ischemia; Laser Coagulation; Male; Neovascularization, Pathologic; Ophthalmic Artery; Prospective Studies; Retinal Vessels; Stents; Sulfonamides; Thiazines; Timolol; Ultrasonography, Doppler, Color; Visual Acuity

2018
Effect of gold nanoparticles on timolol uptake and its release kinetics from contact lenses: In vitro and in vivo evaluation.
    Acta biomaterialia, 2019, 03-01, Volume: 86

    Topics: Animals; Contact Lenses; Drug Liberation; Eye; Gold; Intraocular Pressure; Kinetics; Metal Nanoparticles; Rabbits; Timolol; Tissue Distribution

2019
Computational Model of In Vivo Corneal Pharmacokinetics and Pharmacodynamics of Topically Administered Ophthalmic Drug Products.
    Pharmaceutical research, 2023, Volume: 40, Issue:4

    Topics: Administration, Topical; Animals; Cornea; Eye; Humans; Ophthalmic Solutions; Rabbits; Timolol

2023