Page last updated: 2024-08-16

timolol and diclofenac

timolol has been researched along with diclofenac in 31 studies

Research

Studies (31)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (3.23)	18.7374
1990's	2 (6.45)	18.2507
2000's	15 (48.39)	29.6817
2010's	12 (38.71)	24.3611
2020's	1 (3.23)	2.80

Authors

Authors	Studies
Andrews, PR; Craik, DJ; Martin, JL	1
Topliss, JG; Yoshida, F	1
Faller, B; Wohnsland, F	1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Ascaso Puyuelo, J; Castillo Laguarta, J; Cristobal Bescos, JA; Garcia Garcia, J; Loras Alegre, E; Minana Beamonte, I; Palomar Gomez, A	1
Edwall, L; Kerezoudis, NP; Olgart, L	1
Akura, J; Ibaraki, N; Ichihashi, S; Maekubo, K; Miyake, K; Miyake, S; Ota, I; Shibuya, Y	1
Fiscella, RG; Gaynes, BI; Jensen, M	1
Dommerich, S; Graumüller, S; Hoff, M; Ostwald, J	1
Antinozzi, PP; Caccavale, A; Costagliola, C; Cotticelli, L; Parmeggiani, F; Sebastiani, A	1
Rath, EZ; Rumelt, S	1
Ahmad, L; Iqbal, Z; Khan, A; Khan, AZ; Khan, JA; Khan, S; Nasir, F; Shah, Y	1
Braga, M; Colaço, R; Galante, R; Ghisleni, D; Oliveira, AS; Pinto, TJA; Serro, AP; Topete, A	1
Cetina-Čižmek, B; Filipović-Grčić, J; Hafner, A; Juretić, M; Lovrić, J; Pepić, I	1
Hagström, M; Kidron, H; Rimpelä, AK; Urtti, A	1
Arshad, S; Batool, F; Fu, Q; Shahzad, A; Shahzad, S; Zubair, F	1

Reviews

1 review(s) available for timolol and diclofenac

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

3 trial(s) available for timolol and diclofenac

Article	Year
[Influence of topical administration of diclofenac on the reduction of intraocular pressure induced by timolol in healthy subjects]. Journal francais d'ophtalmologie, 1991, Volume: 14, Issue:2 Topics: Administration, Topical; Depression, Chemical; Diclofenac; Double-Blind Method; Drug Evaluation; Drug Interactions; Humans; Intraocular Pressure; Time Factors; Timolol	1991
Enhanced disruption of the blood-aqueous barrier and the incidence of angiographic cystoid macular edema by topical timolol and its preservative in early postoperative pseudophakia. Archives of ophthalmology (Chicago, Ill. : 1960), 2001, Volume: 119, Issue:3 Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Anterior Eye Segment; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Benzalkonium Compounds; Blood-Aqueous Barrier; Capillary Permeability; Diclofenac; Double-Blind Method; Female; Fluorescein Angiography; Fluorometholone; Glaucoma, Open-Angle; Humans; Incidence; Intraocular Pressure; Macular Edema; Male; Ocular Hypertension; Preservatives, Pharmaceutical; Pseudophakia; Single-Blind Method; Timolol	2001
The influence of diclofenac ophthalmic solution on the intraocular pressure-lowering effect of topical 0.5% timolol and 0.005% latanoprost in primary open-angle glaucoma patients. Experimental eye research, 2005, Volume: 81, Issue:5 Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Diclofenac; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sample Size; Timolol; Tonometry, Ocular	2005

Other Studies

27 other study(ies) available for timolol and diclofenac

Article	Year
Functional group contributions to drug-receptor interactions. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship	1984
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes. Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6 Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water	2001
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability. Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7 Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties	2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human. European journal of medicinal chemistry, 2009, Volume: 44, Issue:4 Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software	2009
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR. European journal of medicinal chemistry, 2011, Volume: 46, Issue:1 Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests	2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Evans blue extravasation in rat dental pulp and oral tissues induced by electrical stimulation of the inferior alveolar nerve. Archives of oral biology, 1993, Volume: 38, Issue:10 Topics: Animals; Blood Proteins; Capillary Permeability; Capsaicin; Chlorisondamine; Dental Pulp; Diclofenac; Electric Stimulation; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Gingiva; Lip; Male; Mandibular Nerve; Methysergide; Phenoxybenzamine; Pyrilamine; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Timolol; Vasodilation	1993
Equivalence of generic and brand-name ophthalmic products. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2001, Apr-01, Volume: 58, Issue:7 Topics: Diclofenac; Drugs, Generic; Humans; Ophthalmic Solutions; Therapeutic Equivalency; Timolol; United States; United States Food and Drug Administration	2001
[Influence of rhinologic usual and unusual drugs on fibroblasts from nasal polyps in cell culture]. Laryngo- rhino- otologie, 2003, Volume: 82, Issue:6 Topics: Administration, Topical; Adrenergic beta-Antagonists; Androstadienes; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Beclomethasone; Calcium Channel Blockers; Cells, Cultured; Culture Media; Diclofenac; Fibroblasts; Fluticasone; Glucocorticoids; Hematologic Agents; Humans; In Vitro Techniques; Mesalamine; Methylprednisolone; Mometasone Furoate; Muscarinic Agonists; Nasal Polyps; Pentoxifylline; Pilocarpine; Piroxicam; Prednisolone; Pregnadienediols; Time Factors; Timolol; Verapamil	2003
Acute visual loss due to serous retinal detachment from acquired optic pit may be a rare presentation of primary open-angle glaucoma. Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2007, Volume: 42, Issue:2 Topics: Acute Disease; Antihypertensive Agents; Diclofenac; Drug Therapy, Combination; Female; Fluorescein Angiography; Glaucoma, Open-Angle; Humans; Middle Aged; Optic Disk; Optic Nerve Diseases; Retinal Detachment; Serum; Sulfonamides; Thiophenes; Timolol; Tomography, Optical Coherence; Vision Disorders; Visual Acuity	2007
Simultaneous determination of timolol maleate, rosuvastatin calcium and diclofenac sodium in pharmaceuticals and physiological fluids using HPLC-UV. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011, Nov-15, Volume: 879, Issue:30 Topics: Animals; Aqueous Humor; Cattle; Chromatography, High Pressure Liquid; Diclofenac; Drug Stability; Fluorobenzenes; Humans; Hydrogen-Ion Concentration; Linear Models; Pyrimidines; Reproducibility of Results; Rosuvastatin Calcium; Sensitivity and Specificity; Sulfonamides; Timolol	2011
Drug-eluting silicone hydrogel for therapeutic contact lenses: Impact of sterilization methods on the system performance. Colloids and surfaces. B, Biointerfaces, 2018, Jan-01, Volume: 161 Topics: Chlorhexidine; Contact Lenses; Diclofenac; Drug Liberation; Gamma Rays; Hydrogels; Levofloxacin; Ophthalmic Solutions; Ozone; Polymers; Silicones; Steam; Sterilization; Timolol	2018
Biopharmaceutical evaluation of surface active ophthalmic excipients using in vitro and ex vivo corneal models. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2018, Jul-30, Volume: 120 Topics: Administration, Ophthalmic; Animals; Biopharmaceutics; Cell Line; Chloramphenicol; Dexamethasone; Diclofenac; Drug Compounding; Dynamic Light Scattering; Electric Impedance; Epithelium, Corneal; Excipients; Female; Glycerol; Humans; Male; Ocular Absorption; Ophthalmic Solutions; Permeability; Pharmaceutical Preparations; Poloxamer; Polyethylene Glycols; Polysorbates; Surface-Active Agents; Sus scrofa; Technology, Pharmaceutical; Time Factors; Timolol	2018
Melanin targeting for intracellular drug delivery: Quantification of bound and free drug in retinal pigment epithelial cells. Journal of controlled release : official journal of the Controlled Release Society, 2018, 08-10, Volume: 283 Topics: Animals; Biological Transport; Cell Line; Chloroquine; Diclofenac; Epithelial Cells; Humans; Melanins; Methotrexate; Molecular Targeted Therapy; Propranolol; Retinal Pigment Epithelium; Swine; Timolol	2018
Development and Validation of Facile RP-HPLC Method for Simultaneous Determination of Timolol Maleate, Moxifloxacin Hydrochloride, Diclofenac Sodium and Dexamethasone in Plasma, Aqueous Humor and Pharmaceutical Products. Journal of chromatographic science, 2023, Aug-19, Volume: 61, Issue:7 Topics: Animals; Aqueous Humor; Cattle; Chromatography, High Pressure Liquid; Dexamethasone; Diclofenac; Humans; Moxifloxacin; Pharmaceutical Preparations; Reproducibility of Results; Timolol	2023