Page last updated: 2024-08-16

timolol and cgp 12177

timolol has been researched along with cgp 12177 in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's4 (50.00)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bultsma, T; Donné-Op den Kelder, GM; Rademaker, B; Timmerman, H1
Baker, JG1
Kaila, T1
Wilkinson, DA; Wilkinson, M1
Baer, M; Chanton, C; Porzig, H1
Ali-Melkkilä, T; Iisalo, E; Kaila, T; Saari, KM; Vuori, ML2
Boutilier, RG; Gamperl, AK; Wilkinson, M1

Trials

2 trial(s) available for timolol and cgp 12177

ArticleYear
Absorption of ocular timolol: drug concentrations and beta-receptor binding activity in the aqueous humour of the treated and contralateral eye.
    Acta ophthalmologica, 1993, Volume: 71, Issue:5

    Topics: Absorption; Administration, Topical; Adrenergic beta-Antagonists; Aged; Animals; Aqueous Humor; Cataract Extraction; Heart Rate; Humans; Lenses, Intraocular; Ophthalmic Solutions; Propanolamines; Rabbits; Radioligand Assay; Rats; Receptors, Adrenergic, beta; Timolol

1993
Beta 1- and beta 2-antagonist activity of topically applied betaxolol and timolol in the systemic circulation.
    Acta ophthalmologica, 1993, Volume: 71, Issue:5

    Topics: Administration, Topical; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Betaxolol; Humans; Middle Aged; Propanolamines; Radioligand Assay; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Timolol

1993

Other Studies

6 other study(ies) available for timolol and cgp 12177

ArticleYear
Mapping of the beta 2-adrenoceptor on Chang liver cells. Differences between high- and low-affinity receptor states.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:6

    Topics: Cell Membrane; Cells, Cultured; Guanylyl Imidodiphosphate; Hydrogen Bonding; Iodocyanopindolol; Liver; Models, Molecular; Pindolol; Protein Conformation; Receptors, Adrenergic, beta; Receptors, Dopamine; Receptors, Dopamine D2; Stereoisomerism; Structure-Activity Relationship

1988
The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors.
    British journal of pharmacology, 2005, Volume: 144, Issue:3

    Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Algorithms; Animals; Cell Line; CHO Cells; Cricetinae; Dioxoles; Humans; Propanolamines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3

2005
A sensitive radioligand binding assay for timolol in plasma.
    Journal of pharmaceutical sciences, 1991, Volume: 80, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Binding, Competitive; Blood Proteins; Cell Membrane; Female; Gas Chromatography-Mass Spectrometry; Humans; In Vitro Techniques; Propanolamines; Radioligand Assay; Rats; Rats, Inbred Strains; Reticulocytes; Timolol

1991
Beta-adrenergic [( 3H]CGP-12177) binding to brain slices and single intact pineal glands.
    Neurochemical research, 1985, Volume: 10, Issue:6

    Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Brain; Cerebral Cortex; Cricetinae; In Vitro Techniques; Isoproterenol; Kinetics; Male; Mesocricetus; Phentolamine; Pineal Gland; Propanolamines; Rats; Rats, Inbred Strains; Timolol

1985
Properties of beta-adrenoceptor sites in metabolizing and nonmetabolizing rat reticulocytes and in resealed reticulocyte ghosts.
    Naunyn-Schmiedeberg's archives of pharmacology, 1981, Volume: 317, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Cell Membrane; Cold Temperature; Cytosol; Dihydroalprenolol; Energy Metabolism; Female; Isoproterenol; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, beta; Reticulocytes; Timolol

1981
Beta-adrenoreceptors in the trout (Oncorhynchus mykiss) heart: characterization, quantification, and effects of repeated catecholamine exposure.
    General and comparative endocrinology, 1994, Volume: 95, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Binding, Competitive; Catecholamines; Down-Regulation; Freezing; Heart; Heart Ventricles; Myocardium; Oncorhynchus mykiss; Propanolamines; Receptors, Adrenergic, beta; Stereoisomerism; Stress, Psychological; Timolol

1994