timolol has been researched along with apraclonidine in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (15.63) | 18.7374 |
| 1990's | 19 (59.38) | 18.2507 |
| 2000's | 5 (15.63) | 29.6817 |
| 2010's | 2 (6.25) | 24.3611 |
| 2020's | 1 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Brubaker, RF; Koskela, T | 1 |
| Arkin, LM; Cummings, HL; Robin, AL; Sulewski, ME | 1 |
| Lee, SH; Lee, SY; Parrow, KA; Shin, DH; Yaldo, MK | 1 |
| Brubaker, RF; Gharagozloo, NZ | 1 |
| Coleman, AL; Robin, AL | 1 |
| Lewis, RA; Shields, MB; Wilkerson, M | 1 |
| Robin, AL | 1 |
| Bacon, DR; Fahrenbach, WF; Van Buskirk, EM | 1 |
| Morrison, JC; Robin, AL | 1 |
| Dandona, L; Morrison, JC; Quigley, HA; Robin, AL | 1 |
| Lehmann, RP; Ritch, R; Shin, DH; Shrader, CE; Stewart, WC; van Buskirk, EM | 1 |
| Chuniaud, M; Demailly, P; Hitchings, RA; Nagasubramanian, S; Pannarale, MR; Parsons, DG; Pecori-Giraldi, J; Stodtmeister, R | 1 |
| Bausher, L; Horio, B; Matsui, H; Mead, A; Sears, M | 1 |
| Horwitz, B; Kottler, M; Laibovitz, R; Ritch, R; Stewart, RH; Stewart, WC | 1 |
| Alçelik, T; Caglar, Y; Elibol, O; Yüksel, N | 1 |
| Lee, MS; Pasha, M; Weitzman, M | 1 |
| Burnstein, Y; Higginbotham, EJ; Shelton, K | 1 |
| Brubaker, R; Dinslage, S; McLaren, J | 1 |
| Kaya, M; Mete, U; Ozdemir, N; Polat, S; Soylu, M; Unlügenç, Z | 1 |
| Brubaker, RF; Maus, TL; Nau, C | 1 |
| Kaufman, PF | 1 |
| Konstas, AG; Maltezos, A; Mantziris, DA; Sine, CS; Stewart, WC | 1 |
| Cheung, J; Sharma, S | 1 |
| Connor, TB; Dev, S; Han, DP; Mieler, WF; Mittra, RA; Pollack, JS; Pulido, JS | 1 |
| Oruç, S; Sener, EC | 1 |
| Chua, JK; Lai, JS; Lam, DS; Tham, CC | 1 |
| Besada, E; Frauens, BJ; Shechtman, D | 1 |
| Dot, C; El Chehab, H; Giraud, JM; Le Corre, A; Ract-Madoux, G; Swalduz, B | 1 |
| Alagoz, G; Altun, G; Celik, E; Turkoglu, EB | 1 |
| Asghari, A; Ozmaie, S; Rajaei, SM; Ziadi, A | 1 |
1 review(s) available for timolol and apraclonidine
| Article | Year |
|---|---|
Assessment of ocular hypotensive mechanisms and additivity of antiglaucoma drugs in humans.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Aqueous Humor; Brimonidine Tartrate; Clonidine; Drug Synergism; Humans; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Timolol | 1999 |
19 trial(s) available for timolol and apraclonidine
| Article | Year |
|---|---|
Apraclonidine and timolol. Combined effects in previously untreated normal subjects.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Aqueous Humor; Circadian Rhythm; Clonidine; Drug Therapy, Combination; Fluorescein; Fluoresceins; Humans; Intraocular Pressure; Random Allocation; Timolol | 1991 |
Effects of topical flurbiprofen on the intraocular pressure lowering effects of apraclonidine and timolol.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Adult; Clonidine; Double-Blind Method; Evaluation Studies as Topic; Female; Flurbiprofen; Humans; Intraocular Pressure; Male; Middle Aged; Premedication; Prospective Studies; Timolol | 1991 |
Additive effect of 1% apraclonidine hydrochloride to nonselective beta-blockers.
Topics: Adrenergic alpha-Agonists; Clonidine; Double-Blind Method; Drug Synergism; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Levobunolol; Male; Ocular Hypertension; Prospective Studies; Random Allocation; Timolol | 1991 |
Effect of apraclonidine in long-term timolol users.
Topics: Adrenergic alpha-Agonists; Aged; Aqueous Humor; Clonidine; Double-Blind Method; Drug Administration Schedule; Drug Interactions; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Secretory Rate; Timolol | 1991 |
Apraclonidine hydrochloride: an evaluation of plasma concentrations, and a comparison of its intraocular pressure lowering and cardiovascular effects to timolol maleate.
Topics: Adrenergic alpha-Agonists; Adult; Blood Pressure; Clonidine; Double-Blind Method; Evaluation Studies as Topic; Female; Heart Rate; Hemodynamics; Humans; Intraocular Pressure; Middle Aged; Ophthalmic Solutions; Prospective Studies; Timolol | 1990 |
Follicular conjunctivitis associated with apraclonidine.
Topics: Adult; Clonidine; Conjunctivitis; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Timolol | 1991 |
Adjunctive glaucoma therapy. A comparison of apraclonidine to dipivefrin when added to timolol maleate.
Topics: Adult; Aged; Clinical Trials as Topic; Clonidine; Drug Therapy, Combination; Epinephrine; Eye Diseases; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Timolol | 1989 |
"Outlier" intraocular pressure readings: valid or invalid for statistical analysis?
Topics: Analysis of Variance; Clinical Trials as Topic; Clonidine; Data Interpretation, Statistical; Double-Blind Method; Drug Therapy, Combination; Epinephrine; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Random Allocation; Timolol | 1989 |
The efficacy of apraclonidine as an adjunct to timolol therapy. Apraclonidine Adjunctive Therapy Study Group.
Topics: Adrenergic alpha-Agonists; Chemotherapy, Adjuvant; Clonidine; Double-Blind Method; Drug Administration Schedule; Drug Synergism; Drug Tolerance; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol | 1995 |
Comparison of apraclonidine and timolol in chronic open-angle glaucoma. A three-month study.
Topics: Adult; Aged; Aged, 80 and over; Chronic Disease; Clonidine; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Timolol | 1993 |
A 90-day study of the efficacy and side effects of 0.25% and 0.5% apraclonidine vs 0.5% timolol. Apraclonidine Primary Therapy Study Group.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Clonidine; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol | 1996 |
Short-term effect of apraclonidine on intraocular pressure in glaucoma patients receiving timolol and pilocarpine.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Aged; Clonidine; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Ophthalmic Solutions; Pilocarpine; Prospective Studies; Timolol | 1997 |
Comparison of the early effects of brimonidine and apraclonidine as topical ocular hypotensive agents.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Antihypertensive Agents; Aqueous Humor; Brimonidine Tartrate; Clonidine; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Fluorophotometry; Humans; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Timolol | 1999 |
The comparative ocular hypotensive effect of apraclonidine with timolol maleate in exfoliation versus primary open-angle glaucoma patients.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Aged; Circadian Rhythm; Clonidine; Drug Therapy, Combination; Exfoliation Syndrome; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Timolol | 1999 |
The use of topical aqueous suppressants in the prevention of postoperative intraocular pressure elevation after pars plana vitrectomy with long-acting gas tamponade.
Topics: Administration, Topical; Antihypertensive Agents; Aqueous Humor; Brimonidine Tartrate; Clonidine; Fluorocarbons; Humans; Intraocular Pressure; Ocular Hypertension; Prospective Studies; Quinoxalines; Sulfonamides; Sulfur Hexafluoride; Thiophenes; Timolol; Vitrectomy | 2000 |
A comparative study on the effects of apraclonidine and timolol on the ophthalmic blood flow velocity waveforms.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Blood Flow Velocity; Blood Pressure; Clonidine; Cross-Over Studies; Double-Blind Method; Female; Humans; Intraocular Pressure; Male; Ophthalmic Artery; Ophthalmic Solutions; Prospective Studies; Reference Values; Retinal Artery; Timolol; Ultrasonography, Doppler | 1999 |
[Efficacy of prophylactic treatment of intraocular pressure spikes due to intravitreal injections].
Topics: Acetazolamide; Aged; Antibodies, Monoclonal, Humanized; Antihypertensive Agents; Bevacizumab; Brimonidine Tartrate; Chemoprevention; Clonidine; Drug Combinations; Female; Humans; Hypotonic Solutions; Intraocular Pressure; Intravitreal Injections; Macular Degeneration; Male; Ocular Hypertension; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2012 |
Short-term effect of topical brinzolamide 1%-timolol 0.5% fixed combination on human central corneal thickness.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Aged; Capsule Opacification; Carbonic Anhydrase Inhibitors; Clonidine; Cornea; Corneal Pachymetry; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Lasers, Solid-State; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiazines; Timolol | 2015 |
Effect of Topically Applied 0.5% Apraclonidine Versus 0.5% Timolol Maleate on Intraocular Pressure of Healthy Horses.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Double-Blind Method; Female; Horse Diseases; Horses; Intraocular Pressure; Lubricant Eye Drops; Ocular Hypertension; Timolol | 2022 |
12 other study(ies) available for timolol and apraclonidine
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
The role of apraclonidine hydrochloride in laser therapy for glaucoma.
Topics: Acetazolamide; Adult; Aged; Animals; Clonidine; Epinephrine; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Iris; Laser Therapy; Macaca fascicularis; Male; Middle Aged; Pilocarpine; Postoperative Complications; Timolol; Trabeculectomy | 1989 |
Replication of ciliary vasomotor effects with controlled intravascular corrosion casting.
Topics: Animals; Aqueous Humor; Arterioles; Ciliary Body; Clonidine; Moxisylyte; Phenylephrine; Rabbits; Timolol; Vasomotor System | 1989 |
Regulation and bioelectrical effects of cyclic adenosine monophosphate production in the ciliary epithelial bilayer.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Aqueous Humor; Ciliary Body; Clonidine; Colforsin; Cyclic AMP; Electrophysiology; Isoproterenol; Male; Membrane Potentials; Pigment Epithelium of Eye; Rabbits; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta; Timolol; Vasoactive Intestinal Peptide | 1996 |
The effect of aqueous humor suppressants on intravitreal gas bubble duration in rabbits.
Topics: Absorption; Administration, Topical; Animals; Aqueous Humor; Clonidine; Fluorocarbons; Injections; Intraocular Pressure; Rabbits; Sulfonamides; Sulfur Hexafluoride; Thiophenes; Time Factors; Timolol; Vitreous Body | 1998 |
Glaucomatocyclitic crisis in a child.
Topics: Adolescent; Clonidine; Corneal Edema; Diagnosis, Differential; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Male; Pain; Prednisolone; Sulfonamides; Syndrome; Thiophenes; Timolol; Uveitis, Intermediate; Vision Disorders; Visual Acuity | 1998 |
Intraocular pressure in rabbits by telemetry II: effects of animal handling and drugs.
Topics: Animal Husbandry; Animals; Circadian Rhythm; Clonidine; Epinephrine; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Pilocarpine; Prostaglandins F, Synthetic; Rabbits; Sulfonamides; Telemetry; Thiophenes; Timolol; Tonometry, Ocular | 1998 |
Ultrastructural effects of topical beta-adrenergic antagonists and an alpha-adrenergic agonist on the rabbit cornea.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Betaxolol; Clonidine; Cornea; Cytoplasm; Endoplasmic Reticulum; Levobunolol; Microvilli; Ophthalmic Solutions; Rabbits; Timolol | 1999 |
Ophthaproblem. Acute angle-closure glaucoma.
Topics: Acetazolamide; Acute Disease; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Clonidine; Diagnosis, Differential; Glaucoma, Angle-Closure; Humans; Intraocular Pressure; Laser Therapy; Male; Middle Aged; Miotics; Ophthalmic Solutions; Pilocarpine; Timolol | 2000 |
Immediate diode laser peripheral iridoplasty as treatment of acute attack of primary angle closure glaucoma: a preliminary study.
Topics: Acute Disease; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Clonidine; Female; Glaucoma, Angle-Closure; Humans; Intraocular Pressure; Iris; Laser Therapy; Male; Middle Aged; Miotics; Pilocarpine; Timolol; Tonometry, Ocular; Treatment Outcome | 2001 |
Recurrent serous macular detachment after topical ocular hypotensive medication.
Topics: Administration, Topical; Antihypertensive Agents; Clonidine; Drug Combinations; Drug Therapy, Combination; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Recurrence; Retinal Detachment; Serum; Sulfonamides; Thiophenes; Timolol; Tomography, Optical Coherence; Visual Acuity | 2008 |