Page last updated: 2024-08-16

timolol and apraclonidine

timolol has been researched along with apraclonidine in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19905 (15.63)18.7374
1990's19 (59.38)18.2507
2000's5 (15.63)29.6817
2010's2 (6.25)24.3611
2020's1 (3.13)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Brubaker, RF; Koskela, T1
Arkin, LM; Cummings, HL; Robin, AL; Sulewski, ME1
Lee, SH; Lee, SY; Parrow, KA; Shin, DH; Yaldo, MK1
Brubaker, RF; Gharagozloo, NZ1
Coleman, AL; Robin, AL1
Lewis, RA; Shields, MB; Wilkerson, M1
Robin, AL1
Bacon, DR; Fahrenbach, WF; Van Buskirk, EM1
Morrison, JC; Robin, AL1
Dandona, L; Morrison, JC; Quigley, HA; Robin, AL1
Lehmann, RP; Ritch, R; Shin, DH; Shrader, CE; Stewart, WC; van Buskirk, EM1
Chuniaud, M; Demailly, P; Hitchings, RA; Nagasubramanian, S; Pannarale, MR; Parsons, DG; Pecori-Giraldi, J; Stodtmeister, R1
Bausher, L; Horio, B; Matsui, H; Mead, A; Sears, M1
Horwitz, B; Kottler, M; Laibovitz, R; Ritch, R; Stewart, RH; Stewart, WC1
Alçelik, T; Caglar, Y; Elibol, O; Yüksel, N1
Lee, MS; Pasha, M; Weitzman, M1
Burnstein, Y; Higginbotham, EJ; Shelton, K1
Brubaker, R; Dinslage, S; McLaren, J1
Kaya, M; Mete, U; Ozdemir, N; Polat, S; Soylu, M; Unlügenç, Z1
Brubaker, RF; Maus, TL; Nau, C1
Kaufman, PF1
Konstas, AG; Maltezos, A; Mantziris, DA; Sine, CS; Stewart, WC1
Cheung, J; Sharma, S1
Connor, TB; Dev, S; Han, DP; Mieler, WF; Mittra, RA; Pollack, JS; Pulido, JS1
Oruç, S; Sener, EC1
Chua, JK; Lai, JS; Lam, DS; Tham, CC1
Besada, E; Frauens, BJ; Shechtman, D1
Dot, C; El Chehab, H; Giraud, JM; Le Corre, A; Ract-Madoux, G; Swalduz, B1
Alagoz, G; Altun, G; Celik, E; Turkoglu, EB1
Asghari, A; Ozmaie, S; Rajaei, SM; Ziadi, A1

Reviews

1 review(s) available for timolol and apraclonidine

ArticleYear
Assessment of ocular hypotensive mechanisms and additivity of antiglaucoma drugs in humans.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1999, Volume: 117, Issue:5

    Topics: Administration, Topical; Adrenergic alpha-Agonists; Aqueous Humor; Brimonidine Tartrate; Clonidine; Drug Synergism; Humans; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Timolol

1999

Trials

19 trial(s) available for timolol and apraclonidine

ArticleYear
Apraclonidine and timolol. Combined effects in previously untreated normal subjects.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1991, Volume: 109, Issue:6

    Topics: Administration, Topical; Adrenergic alpha-Agonists; Aqueous Humor; Circadian Rhythm; Clonidine; Drug Therapy, Combination; Fluorescein; Fluoresceins; Humans; Intraocular Pressure; Random Allocation; Timolol

1991
Effects of topical flurbiprofen on the intraocular pressure lowering effects of apraclonidine and timolol.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1991, Volume: 109, Issue:6

    Topics: Administration, Topical; Adrenergic alpha-Agonists; Adult; Clonidine; Double-Blind Method; Evaluation Studies as Topic; Female; Flurbiprofen; Humans; Intraocular Pressure; Male; Middle Aged; Premedication; Prospective Studies; Timolol

1991
Additive effect of 1% apraclonidine hydrochloride to nonselective beta-blockers.
    Ophthalmology, 1991, Volume: 98, Issue:7

    Topics: Adrenergic alpha-Agonists; Clonidine; Double-Blind Method; Drug Synergism; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Levobunolol; Male; Ocular Hypertension; Prospective Studies; Random Allocation; Timolol

1991
Effect of apraclonidine in long-term timolol users.
    Ophthalmology, 1991, Volume: 98, Issue:10

    Topics: Adrenergic alpha-Agonists; Aged; Aqueous Humor; Clonidine; Double-Blind Method; Drug Administration Schedule; Drug Interactions; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Secretory Rate; Timolol

1991
Apraclonidine hydrochloride: an evaluation of plasma concentrations, and a comparison of its intraocular pressure lowering and cardiovascular effects to timolol maleate.
    Transactions of the American Ophthalmological Society, 1990, Volume: 88

    Topics: Adrenergic alpha-Agonists; Adult; Blood Pressure; Clonidine; Double-Blind Method; Evaluation Studies as Topic; Female; Heart Rate; Hemodynamics; Humans; Intraocular Pressure; Middle Aged; Ophthalmic Solutions; Prospective Studies; Timolol

1990
Follicular conjunctivitis associated with apraclonidine.
    American journal of ophthalmology, 1991, Jan-15, Volume: 111, Issue:1

    Topics: Adult; Clonidine; Conjunctivitis; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Timolol

1991
Adjunctive glaucoma therapy. A comparison of apraclonidine to dipivefrin when added to timolol maleate.
    Ophthalmology, 1989, Volume: 96, Issue:1

    Topics: Adult; Aged; Clinical Trials as Topic; Clonidine; Drug Therapy, Combination; Epinephrine; Eye Diseases; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Timolol

1989
"Outlier" intraocular pressure readings: valid or invalid for statistical analysis?
    Ophthalmic surgery, 1989, Volume: 20, Issue:10

    Topics: Analysis of Variance; Clinical Trials as Topic; Clonidine; Data Interpretation, Statistical; Double-Blind Method; Drug Therapy, Combination; Epinephrine; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Random Allocation; Timolol

1989
The efficacy of apraclonidine as an adjunct to timolol therapy. Apraclonidine Adjunctive Therapy Study Group.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1995, Volume: 113, Issue:3

    Topics: Adrenergic alpha-Agonists; Chemotherapy, Adjuvant; Clonidine; Double-Blind Method; Drug Administration Schedule; Drug Synergism; Drug Tolerance; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol

1995
Comparison of apraclonidine and timolol in chronic open-angle glaucoma. A three-month study.
    Ophthalmology, 1993, Volume: 100, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Chronic Disease; Clonidine; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Timolol

1993
A 90-day study of the efficacy and side effects of 0.25% and 0.5% apraclonidine vs 0.5% timolol. Apraclonidine Primary Therapy Study Group.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1996, Volume: 114, Issue:8

    Topics: Administration, Topical; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Clonidine; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol

1996
Short-term effect of apraclonidine on intraocular pressure in glaucoma patients receiving timolol and pilocarpine.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1997, Volume: 211, Issue:6

    Topics: Administration, Topical; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Aged; Clonidine; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Ophthalmic Solutions; Pilocarpine; Prospective Studies; Timolol

1997
Comparison of the early effects of brimonidine and apraclonidine as topical ocular hypotensive agents.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1999, Volume: 117, Issue:5

    Topics: Administration, Topical; Adrenergic alpha-Agonists; Antihypertensive Agents; Aqueous Humor; Brimonidine Tartrate; Clonidine; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Fluorophotometry; Humans; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Timolol

1999
The comparative ocular hypotensive effect of apraclonidine with timolol maleate in exfoliation versus primary open-angle glaucoma patients.
    Eye (London, England), 1999, Volume: 13 ( Pt 3a)

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Aged; Circadian Rhythm; Clonidine; Drug Therapy, Combination; Exfoliation Syndrome; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Timolol

1999
The use of topical aqueous suppressants in the prevention of postoperative intraocular pressure elevation after pars plana vitrectomy with long-acting gas tamponade.
    Ophthalmology, 2000, Volume: 107, Issue:3

    Topics: Administration, Topical; Antihypertensive Agents; Aqueous Humor; Brimonidine Tartrate; Clonidine; Fluorocarbons; Humans; Intraocular Pressure; Ocular Hypertension; Prospective Studies; Quinoxalines; Sulfonamides; Sulfur Hexafluoride; Thiophenes; Timolol; Vitrectomy

2000
A comparative study on the effects of apraclonidine and timolol on the ophthalmic blood flow velocity waveforms.
    International ophthalmology, 1999, Volume: 23, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Blood Flow Velocity; Blood Pressure; Clonidine; Cross-Over Studies; Double-Blind Method; Female; Humans; Intraocular Pressure; Male; Ophthalmic Artery; Ophthalmic Solutions; Prospective Studies; Reference Values; Retinal Artery; Timolol; Ultrasonography, Doppler

1999
[Efficacy of prophylactic treatment of intraocular pressure spikes due to intravitreal injections].
    Journal francais d'ophtalmologie, 2012, Volume: 35, Issue:8

    Topics: Acetazolamide; Aged; Antibodies, Monoclonal, Humanized; Antihypertensive Agents; Bevacizumab; Brimonidine Tartrate; Chemoprevention; Clonidine; Drug Combinations; Female; Humans; Hypotonic Solutions; Intraocular Pressure; Intravitreal Injections; Macular Degeneration; Male; Ocular Hypertension; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome

2012
Short-term effect of topical brinzolamide 1%-timolol 0.5% fixed combination on human central corneal thickness.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2015, Volume: 31, Issue:4

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Aged; Capsule Opacification; Carbonic Anhydrase Inhibitors; Clonidine; Cornea; Corneal Pachymetry; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Lasers, Solid-State; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiazines; Timolol

2015
Effect of Topically Applied 0.5% Apraclonidine Versus 0.5% Timolol Maleate on Intraocular Pressure of Healthy Horses.
    Journal of equine veterinary science, 2022, Volume: 111

    Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Double-Blind Method; Female; Horse Diseases; Horses; Intraocular Pressure; Lubricant Eye Drops; Ocular Hypertension; Timolol

2022

Other Studies

12 other study(ies) available for timolol and apraclonidine

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
The role of apraclonidine hydrochloride in laser therapy for glaucoma.
    Transactions of the American Ophthalmological Society, 1989, Volume: 87

    Topics: Acetazolamide; Adult; Aged; Animals; Clonidine; Epinephrine; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Iris; Laser Therapy; Macaca fascicularis; Male; Middle Aged; Pilocarpine; Postoperative Complications; Timolol; Trabeculectomy

1989
Replication of ciliary vasomotor effects with controlled intravascular corrosion casting.
    Transactions of the American Ophthalmological Society, 1989, Volume: 87

    Topics: Animals; Aqueous Humor; Arterioles; Ciliary Body; Clonidine; Moxisylyte; Phenylephrine; Rabbits; Timolol; Vasomotor System

1989
Regulation and bioelectrical effects of cyclic adenosine monophosphate production in the ciliary epithelial bilayer.
    Investigative ophthalmology & visual science, 1996, Volume: 37, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Aqueous Humor; Ciliary Body; Clonidine; Colforsin; Cyclic AMP; Electrophysiology; Isoproterenol; Male; Membrane Potentials; Pigment Epithelium of Eye; Rabbits; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta; Timolol; Vasoactive Intestinal Peptide

1996
The effect of aqueous humor suppressants on intravitreal gas bubble duration in rabbits.
    American journal of ophthalmology, 1998, Volume: 125, Issue:5

    Topics: Absorption; Administration, Topical; Animals; Aqueous Humor; Clonidine; Fluorocarbons; Injections; Intraocular Pressure; Rabbits; Sulfonamides; Sulfur Hexafluoride; Thiophenes; Time Factors; Timolol; Vitreous Body

1998
Glaucomatocyclitic crisis in a child.
    American journal of ophthalmology, 1998, Volume: 126, Issue:1

    Topics: Adolescent; Clonidine; Corneal Edema; Diagnosis, Differential; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Male; Pain; Prednisolone; Sulfonamides; Syndrome; Thiophenes; Timolol; Uveitis, Intermediate; Vision Disorders; Visual Acuity

1998
Intraocular pressure in rabbits by telemetry II: effects of animal handling and drugs.
    Investigative ophthalmology & visual science, 1998, Volume: 39, Issue:12

    Topics: Animal Husbandry; Animals; Circadian Rhythm; Clonidine; Epinephrine; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Pilocarpine; Prostaglandins F, Synthetic; Rabbits; Sulfonamides; Telemetry; Thiophenes; Timolol; Tonometry, Ocular

1998
Ultrastructural effects of topical beta-adrenergic antagonists and an alpha-adrenergic agonist on the rabbit cornea.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1999, Volume: 213, Issue:3

    Topics: Administration, Topical; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Betaxolol; Clonidine; Cornea; Cytoplasm; Endoplasmic Reticulum; Levobunolol; Microvilli; Ophthalmic Solutions; Rabbits; Timolol

1999
Ophthaproblem. Acute angle-closure glaucoma.
    Canadian family physician Medecin de famille canadien, 2000, Volume: 46

    Topics: Acetazolamide; Acute Disease; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Clonidine; Diagnosis, Differential; Glaucoma, Angle-Closure; Humans; Intraocular Pressure; Laser Therapy; Male; Middle Aged; Miotics; Ophthalmic Solutions; Pilocarpine; Timolol

2000
Immediate diode laser peripheral iridoplasty as treatment of acute attack of primary angle closure glaucoma: a preliminary study.
    Journal of glaucoma, 2001, Volume: 10, Issue:2

    Topics: Acute Disease; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Clonidine; Female; Glaucoma, Angle-Closure; Humans; Intraocular Pressure; Iris; Laser Therapy; Male; Middle Aged; Miotics; Pilocarpine; Timolol; Tonometry, Ocular; Treatment Outcome

2001
Recurrent serous macular detachment after topical ocular hypotensive medication.
    Clinical & experimental optometry, 2008, Volume: 91, Issue:6

    Topics: Administration, Topical; Antihypertensive Agents; Clonidine; Drug Combinations; Drug Therapy, Combination; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Recurrence; Retinal Detachment; Serum; Sulfonamides; Thiophenes; Timolol; Tomography, Optical Coherence; Visual Acuity

2008