timolol has been researched along with alprenolol in 54 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 29 (53.70) | 18.7374 |
1990's | 4 (7.41) | 18.2507 |
2000's | 11 (20.37) | 29.6817 |
2010's | 10 (18.52) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Bultsma, T; Donné-Op den Kelder, GM; Rademaker, B; Timmerman, H | 1 |
Carrupt, PA; el Tayar, N; Testa, B; Van de Waterbeemd, H | 1 |
Andrews, PR; Craik, DJ; Martin, JL | 1 |
Baldwin, JJ; Gross, DM; McClure, DE; Williams, M | 1 |
Carrupt, PA; Gaillard, P; Schambel, P; Testa, B | 1 |
Topliss, JG; Yoshida, F | 1 |
Faller, B; Wohnsland, F | 1 |
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
Baker, JG | 1 |
Caron, G; Ermondi, G | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Bard, B; Carrupt, PA; Martel, S | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
Campillo, NE; Guerra, A; Páez, JA | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Bellman, K; Knegtel, RM; Settimo, L | 1 |
Folkers, K; Kishi, T; Watanabe, T | 1 |
Meier, J | 1 |
Dickerson, DD; Fulmor, IE; Goldberg, ME; Lee, RJ | 1 |
Lund-Johansen, P | 2 |
Kiechel, JR; Meier, J | 1 |
Eliasson, K; Lins, LE; Sundqvist, K | 1 |
Drummer, O; Jarrott, B; Louis, WJ; McNeil, JJ; Rand, MJ | 1 |
Neufeld, AH; Page, ED | 1 |
Heinze, A; Werth, HW; Wessels, F | 1 |
Wilkinson, DA; Wilkinson, M | 1 |
Fishbein, L; Jackson, CD | 1 |
Johansson, SR; McCall, M; Vedin, JA; Wilhelmsson, C | 1 |
Borer, JS; Moses, JW | 1 |
Hampton, JR | 1 |
Le Douarec, JC; Lotti, VJ; Schmitt, C | 1 |
Vedin, A; Wilhelmsson, C | 1 |
Hjalmarson, A | 1 |
Moss, AJ | 1 |
Alvan, G; Calissendorff, BM; Haglund, K; Marén, N; Seideman, P | 1 |
Pratt, CM; Roberts, R | 1 |
Friedewald, WT; Frishman, WH; Furberg, CD | 2 |
Tomov, I | 1 |
Bromberg, BB; Gregory, DS; Sears, ML | 1 |
Gemba, M; Hosaka, K; Kamiyama, M; Kobayashi, I; Konno, C; Maruo, H; Ueno, T | 1 |
Caldwell, GW; Evangelisto, M; Masucci, JA; White, R | 1 |
Caldwell, GW; Demarest, K; Easlick, SM; Gunnet, J; Masucci, JA | 1 |
Pisklak, DM; Wawer, I; Zielińska-Pisklak, MA | 1 |
Chalmers, MJ; Chien, EY; Gatchalian, J; Griffin, PR; Katritch, V; Stevens, RC; West, GM | 1 |
9 review(s) available for timolol and alprenolol
Article | Year |
---|---|
Modeling of beta-adrenoceptors based on molecular electrostatic potential studies of agonists and antagonists.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Models, Molecular; Receptors, Adrenergic, beta; Structure-Activity Relationship | 1988 |
[Comparative pharmacokinetics of beta-blockers].
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Half-Life; Humans; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol; Timolol | 1978 |
A toxicological review of beta-adrenergic blockers.
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Cocarcinogenesis; Ethanolamines; Female; Kinetics; Labetalol; Lethal Dose 50; Male; Metoprolol; Mice; Mutagens; Nadolol; Neoplasms, Experimental; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol; Rats; Sotalol; Timolol | 1986 |
Beta-adrenergic antagonists in the treatment of patients with heart disease.
Topics: Acebutolol; Adrenergic beta-Agonists; Alprenolol; Animals; Arrhythmias, Cardiac; Bronchial Spasm; Cardiomyopathy, Hypertrophic; Coronary Disease; Female; Heart Diseases; Heart Failure; Humans; Hypertension; Metoprolol; Mitral Valve Prolapse; Mitral Valve Stenosis; Nadolol; Nervous System Diseases; Pindolol; Pregnancy; Pregnancy Complications, Cardiovascular; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Structure-Activity Relationship; Timolol | 1981 |
The use of beta blockers for the reduction of mortality after myocardial infarction.
Topics: Adrenergic beta-Antagonists; Alprenolol; Atenolol; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Myocardial Infarction; Norway; Oxprenolol; Practolol; Propranolol; Random Allocation; Timolol | 1981 |
Beta blocking agents: current status in the prevention of sudden coronary death.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Alprenolol; Atenolol; Clinical Trials as Topic; Coronary Disease; Death, Sudden; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Practolol; Propranolol; Prospective Studies; Random Allocation; Timolol | 1982 |
Beta-adrenergic blockade for survivors of acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Arrhythmias, Cardiac; Clinical Trials as Topic; Coronary Disease; Follow-Up Studies; Humans; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol; Time Factors; Timolol | 1984 |
The use of beta-adrenergic blocking drugs in patients with myocardial infarction.
Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Atenolol; Clinical Trials as Topic; Humans; Hypertension; Metoprolol; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Receptors, Adrenergic, beta; Risk; Sotalol; Timolol | 1984 |
[Therapeutic value of the long-term administration of beta-adrenergic blockaders after myocardial infarct].
Topics: Adrenergic beta-Antagonists; Alprenolol; Clinical Trials as Topic; Humans; Metoprolol; Myocardial Infarction; Placebos; Practolol; Propranolol; Random Allocation; Sotalol; Time Factors; Timolol | 1984 |
11 trial(s) available for timolol and alprenolol
Article | Year |
---|---|
Clinical pharmacology of adrenergic-blocking drugs.
Topics: Adrenergic beta-Antagonists; Alprenolol; Biological Availability; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Humans; Hypertension; Pindolol; Placebos; Propranolol; Pulse; Timolol | 1979 |
[Antihypertensive therapy with a new beta-blocking agent Timolol. Double blind study and comparison with Alprenolol and Pindolol (author's transl)].
Topics: Adult; Alprenolol; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Pindolol; Propanolamines; Pulse; Renin; Timolol | 1977 |
Duration of action of beta blockers.
Topics: Adrenergic beta-Antagonists; Adult; Alprenolol; Atenolol; Blood Pressure; Coronary Disease; Heart Rate; Humans; Metoprolol; Penbutolol; Physical Exertion; Pindolol; Propranolol; Regression Analysis; Rest; Sotalol; Time Factors; Timolol | 1980 |
The use of beta blockers for the reduction of mortality after myocardial infarction.
Topics: Adrenergic beta-Antagonists; Alprenolol; Atenolol; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Myocardial Infarction; Norway; Oxprenolol; Practolol; Propranolol; Random Allocation; Timolol | 1981 |
Beta blockers after myocardial infarction--aspects on study design based on current knowledge.
Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Myocardial Infarction; Practolol; Timolol | 1981 |
Beta blocking agents: current status in the prevention of sudden coronary death.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Alprenolol; Atenolol; Clinical Trials as Topic; Coronary Disease; Death, Sudden; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Practolol; Propranolol; Prospective Studies; Random Allocation; Timolol | 1982 |
Postinfarction therapy with beta blockers: who should be treated?
Topics: Adrenergic beta-Antagonists; Alprenolol; Clinical Trials as Topic; Double-Blind Method; Heart; Humans; Metoprolol; Myocardial Infarction; Propranolol; Random Allocation; Timolol | 1982 |
Chronic beta blockade therapy in patients after myocardial infarction.
Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Clinical Trials as Topic; Double-Blind Method; Humans; Metoprolol; Myocardial Infarction; Practolol; Propranolol; Timolol | 1983 |
Beta-adrenergic blockade for survivors of acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Arrhythmias, Cardiac; Clinical Trials as Topic; Coronary Disease; Follow-Up Studies; Humans; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol; Time Factors; Timolol | 1984 |
The use of beta-adrenergic blocking drugs in patients with myocardial infarction.
Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Atenolol; Clinical Trials as Topic; Humans; Hypertension; Metoprolol; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Receptors, Adrenergic, beta; Risk; Sotalol; Timolol | 1984 |
[Therapeutic value of the long-term administration of beta-adrenergic blockaders after myocardial infarct].
Topics: Adrenergic beta-Antagonists; Alprenolol; Clinical Trials as Topic; Humans; Metoprolol; Myocardial Infarction; Placebos; Practolol; Propranolol; Random Allocation; Sotalol; Time Factors; Timolol | 1984 |
39 other study(ies) available for timolol and alprenolol
Article | Year |
---|---|
Mapping of the beta 2-adrenoceptor on Chang liver cells. Differences between high- and low-affinity receptor states.
Topics: Cell Membrane; Cells, Cultured; Guanylyl Imidodiphosphate; Hydrogen Bonding; Iodocyanopindolol; Liver; Models, Molecular; Pindolol; Protein Conformation; Receptors, Adrenergic, beta; Receptors, Dopamine; Receptors, Dopamine D2; Stereoisomerism; Structure-Activity Relationship | 1988 |
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Use of (S)-(trifloxymethyl)oxirane in the synthesis of a chiral beta-adrenoceptor antagonist, (R)- and (S)-9-[[3-(tert-butylamino)-2-hydroxypropyl]oximino]fluorene.
Topics: Adrenergic beta-Antagonists; Animals; Binding, Competitive; Chemical Phenomena; Chemistry; Dihydroalprenolol; Female; Guinea Pigs; Indicators and Reagents; Lung; Muscle Contraction; Muscle, Smooth, Vascular; Myocardium; Propanolamines; Stereoisomerism | 1982 |
Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models.
Topics: Indoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Propanolamines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes | 1996 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water | 2001 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Algorithms; Animals; Cell Line; CHO Cells; Cricetinae; Dioxoles; Humans; Propanolamines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3 | 2005 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography.
Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Bioenergetics in clinical medicine XV. Inhibition of coenzyme Q10-enzymes by clinically used adrenergic blockers of beta-receptors.
Topics: Adrenergic beta-Antagonists; Alprenolol; NADH, NADPH Oxidoreductases; Propranolol; Stereoisomerism; Timolol; Ubiquinone | 1977 |
Pindolol: a pharmacokinetic comparison with other beta-adrenoceptor blocking agents.
Topics: Adrenergic beta-Antagonists; Alprenolol; Biological Availability; Half-Life; Humans; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Protein Binding; Sotalol; Timolol | 1977 |
Direct myocardial depressant effects of several beta-adrenergic blocking agents in the unanesthetized atherosclerotic rabbit.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Arteriosclerosis; Atenolol; Blood Pressure; Depression, Chemical; Heart Rate; Isoproterenol; Male; Oxprenolol; Pindolol; Propanolamines; Propranolol; Rabbits; Timolol | 1978 |
alpha-Methyldopa and beta-blockers in hypertension--a comparison of their haemodynamic effects.
Topics: Adrenergic beta-Antagonists; Alprenolol; Hemodynamics; Humans; Hypertension; Methyldopa; Metoprolol; Physical Exertion; Propranolol; Time Factors; Timolol | 1978 |
Vasospastic phenomena in patients treated with beta-adrenoceptor blocking agents.
Topics: Adrenergic beta-Antagonists; Alprenolol; Blood Circulation; Cardiac Output; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Propranolol; Raynaud Disease; Skin Temperature; Timolol | 1979 |
In vitro determination of the ability of drugs to bind to adrenergic receptors.
Topics: Alprenolol; Animals; Ciliary Body; Clonidine; Dihydroergotoxine; Dopamine; Epinephrine; In Vitro Techniques; Iris; Isoproterenol; Male; Phentolamine; Propranolol; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Timolol | 1977 |
Beta-adrenergic [( 3H]CGP-12177) binding to brain slices and single intact pineal glands.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Brain; Cerebral Cortex; Cricetinae; In Vitro Techniques; Isoproterenol; Kinetics; Male; Mesocricetus; Phentolamine; Pineal Gland; Propanolamines; Rats; Rats, Inbred Strains; Timolol | 1985 |
Penetration of five beta-adrenergic antagonists into the rabbit eye after ocular instillation.
Topics: Administration, Topical; Adrenergic beta-Agonists; Alprenolol; Animals; Aqueous Humor; Chromatography, Gas; Oxprenolol; Practolol; Propranolol; Rabbits; Timolol | 1981 |
Additive intraocular pressure reducing effect of topical timolol during systemic beta-blockade.
Topics: Administration, Oral; Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Alprenolol; Blood Pressure; Female; Humans; Intraocular Pressure; Male; Metoprolol; Middle Aged; Propanolamines; Timolol | 1982 |
Central haemodynamic effects of beta blockers in hypertension. A comparison between atenolol, metoprolol, timolol, penbutolol, alprenolol pindolol and bunitrolol.
Topics: Adrenergic beta-Antagonists; Alprenolol; Atenolol; Hemodynamics; Humans; Hypertension; Metoprolol; Pindolol; Propanolamines; Time Factors; Timolol | 1983 |
Beta-adrenergic receptors in ciliary processes of the rabbit.
Topics: Adenylyl Cyclases; Alprenolol; Animals; Cell Membrane; Ciliary Body; Epinephrine; Isoproterenol; Male; Phentolamine; Pindolol; Propranolol; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, beta; Timolol | 1980 |
Relationship between amount of beta-blockers permeating through the stratum corneum and skin irritation after application of beta-blocker adhesive patches to guinea pig skin.
Topics: Acebutolol; Administration, Cutaneous; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Dermatitis, Irritant; Guinea Pigs; Male; Oxprenolol; Skin; Skin Absorption; Timolol | 1997 |
Evaluation of the immobilized artificial membrane phosphatidylcholine. Drug discovery column for high-performance liquid chromatographic screening of drug-membrane interactions.
Topics: Acebutolol; Acetonitriles; Adrenergic beta-Antagonists; Alprenolol; Aniline Compounds; Atenolol; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Membranes, Artificial; Metoprolol; Models, Chemical; Osmolar Concentration; Oxprenolol; Phosphatidylcholines; Pindolol; Propranolol; Reproducibility of Results; Timolol | 1998 |
In vitro permeability of eight beta-blockers through Caco-2 monolayers utilizing liquid chromatography/electrospray ionization mass spectrometry.
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Atenolol; Biological Availability; Caco-2 Cells; Cell Membrane Permeability; Chromatography, Liquid; Epithelial Cells; Humans; Intestinal Absorption; Intestinal Mucosa; Mass Spectrometry; Metoprolol; Molecular Structure; Oxprenolol; Pindolol; Propranolol; Research Design; Timolol | 1998 |
1H and 13C NMR characteristics of β-blockers.
Topics: Acebutolol; Acids; Adrenergic beta-Antagonists; Alkalies; Alprenolol; Atenolol; Carbazoles; Carbon Isotopes; Carvedilol; Nuclear Magnetic Resonance, Biomolecular; Pindolol; Propanolamines; Propranolol; Protons; Timolol | 2011 |
Ligand-dependent perturbation of the conformational ensemble for the GPCR β2 adrenergic receptor revealed by HDX.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Alprenolol; Binding Sites; Clenbuterol; Deuterium Exchange Measurement; Humans; Hydrogen Bonding; Ligands; Mass Spectrometry; Membranes; Peptides; Propanolamines; Protein Binding; Protein Stability; Protein Structure, Tertiary; Receptors, Adrenergic, beta-2; Timolol | 2011 |