Page last updated: 2024-08-16

timolol and alprenolol

timolol has been researched along with alprenolol in 54 studies

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-199029 (53.70)18.7374
1990's4 (7.41)18.2507
2000's11 (20.37)29.6817
2010's10 (18.52)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bultsma, T; Donné-Op den Kelder, GM; Rademaker, B; Timmerman, H1
Carrupt, PA; el Tayar, N; Testa, B; Van de Waterbeemd, H1
Andrews, PR; Craik, DJ; Martin, JL1
Baldwin, JJ; Gross, DM; McClure, DE; Williams, M1
Carrupt, PA; Gaillard, P; Schambel, P; Testa, B1
Topliss, JG; Yoshida, F1
Faller, B; Wohnsland, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Baker, JG1
Caron, G; Ermondi, G1
Lombardo, F; Obach, RS; Waters, NJ1
Bard, B; Carrupt, PA; Martel, S1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Folkers, K; Kishi, T; Watanabe, T1
Meier, J1
Dickerson, DD; Fulmor, IE; Goldberg, ME; Lee, RJ1
Lund-Johansen, P2
Kiechel, JR; Meier, J1
Eliasson, K; Lins, LE; Sundqvist, K1
Drummer, O; Jarrott, B; Louis, WJ; McNeil, JJ; Rand, MJ1
Neufeld, AH; Page, ED1
Heinze, A; Werth, HW; Wessels, F1
Wilkinson, DA; Wilkinson, M1
Fishbein, L; Jackson, CD1
Johansson, SR; McCall, M; Vedin, JA; Wilhelmsson, C1
Borer, JS; Moses, JW1
Hampton, JR1
Le Douarec, JC; Lotti, VJ; Schmitt, C1
Vedin, A; Wilhelmsson, C1
Hjalmarson, A1
Moss, AJ1
Alvan, G; Calissendorff, BM; Haglund, K; Marén, N; Seideman, P1
Pratt, CM; Roberts, R1
Friedewald, WT; Frishman, WH; Furberg, CD2
Tomov, I1
Bromberg, BB; Gregory, DS; Sears, ML1
Gemba, M; Hosaka, K; Kamiyama, M; Kobayashi, I; Konno, C; Maruo, H; Ueno, T1
Caldwell, GW; Evangelisto, M; Masucci, JA; White, R1
Caldwell, GW; Demarest, K; Easlick, SM; Gunnet, J; Masucci, JA1
Pisklak, DM; Wawer, I; Zielińska-Pisklak, MA1
Chalmers, MJ; Chien, EY; Gatchalian, J; Griffin, PR; Katritch, V; Stevens, RC; West, GM1

Reviews

9 review(s) available for timolol and alprenolol

ArticleYear
Modeling of beta-adrenoceptors based on molecular electrostatic potential studies of agonists and antagonists.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:11

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Models, Molecular; Receptors, Adrenergic, beta; Structure-Activity Relationship

1988
[Comparative pharmacokinetics of beta-blockers].
    La Nouvelle presse medicale, 1978, Sep-20, Volume: 7, Issue:31

    Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Half-Life; Humans; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol; Timolol

1978
A toxicological review of beta-adrenergic blockers.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1986, Volume: 6, Issue:3

    Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Cocarcinogenesis; Ethanolamines; Female; Kinetics; Labetalol; Lethal Dose 50; Male; Metoprolol; Mice; Mutagens; Nadolol; Neoplasms, Experimental; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol; Rats; Sotalol; Timolol

1986
Beta-adrenergic antagonists in the treatment of patients with heart disease.
    Disease-a-month : DM, 1981, Volume: 27, Issue:9

    Topics: Acebutolol; Adrenergic beta-Agonists; Alprenolol; Animals; Arrhythmias, Cardiac; Bronchial Spasm; Cardiomyopathy, Hypertrophic; Coronary Disease; Female; Heart Diseases; Heart Failure; Humans; Hypertension; Metoprolol; Mitral Valve Prolapse; Mitral Valve Stenosis; Nadolol; Nervous System Diseases; Pindolol; Pregnancy; Pregnancy Complications, Cardiovascular; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Structure-Activity Relationship; Timolol

1981
The use of beta blockers for the reduction of mortality after myocardial infarction.
    European heart journal, 1981, Volume: 2, Issue:4

    Topics: Adrenergic beta-Antagonists; Alprenolol; Atenolol; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Myocardial Infarction; Norway; Oxprenolol; Practolol; Propranolol; Random Allocation; Timolol

1981
Beta blocking agents: current status in the prevention of sudden coronary death.
    Annals of the New York Academy of Sciences, 1982, Volume: 382

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Alprenolol; Atenolol; Clinical Trials as Topic; Coronary Disease; Death, Sudden; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Practolol; Propranolol; Prospective Studies; Random Allocation; Timolol

1982
Beta-adrenergic blockade for survivors of acute myocardial infarction.
    The New England journal of medicine, 1984, Mar-29, Volume: 310, Issue:13

    Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Arrhythmias, Cardiac; Clinical Trials as Topic; Coronary Disease; Follow-Up Studies; Humans; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol; Time Factors; Timolol

1984
The use of beta-adrenergic blocking drugs in patients with myocardial infarction.
    Current problems in cardiology, 1984, Volume: 9, Issue:3

    Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Atenolol; Clinical Trials as Topic; Humans; Hypertension; Metoprolol; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Receptors, Adrenergic, beta; Risk; Sotalol; Timolol

1984
[Therapeutic value of the long-term administration of beta-adrenergic blockaders after myocardial infarct].
    Vutreshni bolesti, 1984, Volume: 23, Issue:3

    Topics: Adrenergic beta-Antagonists; Alprenolol; Clinical Trials as Topic; Humans; Metoprolol; Myocardial Infarction; Placebos; Practolol; Propranolol; Random Allocation; Sotalol; Time Factors; Timolol

1984

Trials

11 trial(s) available for timolol and alprenolol

ArticleYear
Clinical pharmacology of adrenergic-blocking drugs.
    Cardiology, 1979, Volume: 64 Suppl 1

    Topics: Adrenergic beta-Antagonists; Alprenolol; Biological Availability; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Humans; Hypertension; Pindolol; Placebos; Propranolol; Pulse; Timolol

1979
[Antihypertensive therapy with a new beta-blocking agent Timolol. Double blind study and comparison with Alprenolol and Pindolol (author's transl)].
    Medizinische Klinik, 1977, Oct-14, Volume: 72, Issue:41

    Topics: Adult; Alprenolol; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Pindolol; Propanolamines; Pulse; Renin; Timolol

1977
Duration of action of beta blockers.
    Clinical pharmacology and therapeutics, 1980, Volume: 27, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Alprenolol; Atenolol; Blood Pressure; Coronary Disease; Heart Rate; Humans; Metoprolol; Penbutolol; Physical Exertion; Pindolol; Propranolol; Regression Analysis; Rest; Sotalol; Time Factors; Timolol

1980
The use of beta blockers for the reduction of mortality after myocardial infarction.
    European heart journal, 1981, Volume: 2, Issue:4

    Topics: Adrenergic beta-Antagonists; Alprenolol; Atenolol; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Myocardial Infarction; Norway; Oxprenolol; Practolol; Propranolol; Random Allocation; Timolol

1981
Beta blockers after myocardial infarction--aspects on study design based on current knowledge.
    Acta medica Scandinavica. Supplementum, 1981, Volume: 651

    Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Myocardial Infarction; Practolol; Timolol

1981
Beta blocking agents: current status in the prevention of sudden coronary death.
    Annals of the New York Academy of Sciences, 1982, Volume: 382

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Alprenolol; Atenolol; Clinical Trials as Topic; Coronary Disease; Death, Sudden; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Practolol; Propranolol; Prospective Studies; Random Allocation; Timolol

1982
Postinfarction therapy with beta blockers: who should be treated?
    International journal of cardiology, 1982, Volume: 1, Issue:5-6

    Topics: Adrenergic beta-Antagonists; Alprenolol; Clinical Trials as Topic; Double-Blind Method; Heart; Humans; Metoprolol; Myocardial Infarction; Propranolol; Random Allocation; Timolol

1982
Chronic beta blockade therapy in patients after myocardial infarction.
    The American journal of cardiology, 1983, Oct-01, Volume: 52, Issue:7

    Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Clinical Trials as Topic; Double-Blind Method; Humans; Metoprolol; Myocardial Infarction; Practolol; Propranolol; Timolol

1983
Beta-adrenergic blockade for survivors of acute myocardial infarction.
    The New England journal of medicine, 1984, Mar-29, Volume: 310, Issue:13

    Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Arrhythmias, Cardiac; Clinical Trials as Topic; Coronary Disease; Follow-Up Studies; Humans; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol; Time Factors; Timolol

1984
The use of beta-adrenergic blocking drugs in patients with myocardial infarction.
    Current problems in cardiology, 1984, Volume: 9, Issue:3

    Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Atenolol; Clinical Trials as Topic; Humans; Hypertension; Metoprolol; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Receptors, Adrenergic, beta; Risk; Sotalol; Timolol

1984
[Therapeutic value of the long-term administration of beta-adrenergic blockaders after myocardial infarct].
    Vutreshni bolesti, 1984, Volume: 23, Issue:3

    Topics: Adrenergic beta-Antagonists; Alprenolol; Clinical Trials as Topic; Humans; Metoprolol; Myocardial Infarction; Placebos; Practolol; Propranolol; Random Allocation; Sotalol; Time Factors; Timolol

1984

Other Studies

39 other study(ies) available for timolol and alprenolol

ArticleYear
Mapping of the beta 2-adrenoceptor on Chang liver cells. Differences between high- and low-affinity receptor states.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:6

    Topics: Cell Membrane; Cells, Cultured; Guanylyl Imidodiphosphate; Hydrogen Bonding; Iodocyanopindolol; Liver; Models, Molecular; Pindolol; Protein Conformation; Receptors, Adrenergic, beta; Receptors, Dopamine; Receptors, Dopamine D2; Stereoisomerism; Structure-Activity Relationship

1988
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Use of (S)-(trifloxymethyl)oxirane in the synthesis of a chiral beta-adrenoceptor antagonist, (R)- and (S)-9-[[3-(tert-butylamino)-2-hydroxypropyl]oximino]fluorene.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:8

    Topics: Adrenergic beta-Antagonists; Animals; Binding, Competitive; Chemical Phenomena; Chemistry; Dihydroalprenolol; Female; Guinea Pigs; Indicators and Reagents; Lung; Muscle Contraction; Muscle, Smooth, Vascular; Myocardium; Propanolamines; Stereoisomerism

1982
Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models.
    Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1

    Topics: Indoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Propanolamines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes

1996
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
    Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6

    Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water

2001
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors.
    British journal of pharmacology, 2005, Volume: 144, Issue:3

    Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Algorithms; Animals; Cell Line; CHO Cells; Cricetinae; Dioxoles; Humans; Propanolamines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3

2005
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography.
    Journal of medicinal chemistry, 2009, May-28, Volume: 52, Issue:10

    Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Bioenergetics in clinical medicine XV. Inhibition of coenzyme Q10-enzymes by clinically used adrenergic blockers of beta-receptors.
    Research communications in chemical pathology and pharmacology, 1977, Volume: 17, Issue:1

    Topics: Adrenergic beta-Antagonists; Alprenolol; NADH, NADPH Oxidoreductases; Propranolol; Stereoisomerism; Timolol; Ubiquinone

1977
Pindolol: a pharmacokinetic comparison with other beta-adrenoceptor blocking agents.
    Acta medica Scandinavica. Supplementum, 1977, Volume: 606

    Topics: Adrenergic beta-Antagonists; Alprenolol; Biological Availability; Half-Life; Humans; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Protein Binding; Sotalol; Timolol

1977
Direct myocardial depressant effects of several beta-adrenergic blocking agents in the unanesthetized atherosclerotic rabbit.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1978, Volume: 158, Issue:2

    Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Arteriosclerosis; Atenolol; Blood Pressure; Depression, Chemical; Heart Rate; Isoproterenol; Male; Oxprenolol; Pindolol; Propanolamines; Propranolol; Rabbits; Timolol

1978
alpha-Methyldopa and beta-blockers in hypertension--a comparison of their haemodynamic effects.
    Clinical and experimental pharmacology & physiology. Supplement, 1978, Volume: 4

    Topics: Adrenergic beta-Antagonists; Alprenolol; Hemodynamics; Humans; Hypertension; Methyldopa; Metoprolol; Physical Exertion; Propranolol; Time Factors; Timolol

1978
Vasospastic phenomena in patients treated with beta-adrenoceptor blocking agents.
    Acta medica Scandinavica. Supplementum, 1979, Volume: 628

    Topics: Adrenergic beta-Antagonists; Alprenolol; Blood Circulation; Cardiac Output; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Propranolol; Raynaud Disease; Skin Temperature; Timolol

1979
In vitro determination of the ability of drugs to bind to adrenergic receptors.
    Investigative ophthalmology & visual science, 1977, Volume: 16, Issue:12

    Topics: Alprenolol; Animals; Ciliary Body; Clonidine; Dihydroergotoxine; Dopamine; Epinephrine; In Vitro Techniques; Iris; Isoproterenol; Male; Phentolamine; Propranolol; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Timolol

1977
Beta-adrenergic [( 3H]CGP-12177) binding to brain slices and single intact pineal glands.
    Neurochemical research, 1985, Volume: 10, Issue:6

    Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Brain; Cerebral Cortex; Cricetinae; In Vitro Techniques; Isoproterenol; Kinetics; Male; Mesocricetus; Phentolamine; Pineal Gland; Propanolamines; Rats; Rats, Inbred Strains; Timolol

1985
Penetration of five beta-adrenergic antagonists into the rabbit eye after ocular instillation.
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1981, Volume: 217, Issue:3

    Topics: Administration, Topical; Adrenergic beta-Agonists; Alprenolol; Animals; Aqueous Humor; Chromatography, Gas; Oxprenolol; Practolol; Propranolol; Rabbits; Timolol

1981
Additive intraocular pressure reducing effect of topical timolol during systemic beta-blockade.
    Acta ophthalmologica, 1982, Volume: 60, Issue:1

    Topics: Administration, Oral; Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Alprenolol; Blood Pressure; Female; Humans; Intraocular Pressure; Male; Metoprolol; Middle Aged; Propanolamines; Timolol

1982
Central haemodynamic effects of beta blockers in hypertension. A comparison between atenolol, metoprolol, timolol, penbutolol, alprenolol pindolol and bunitrolol.
    European heart journal, 1983, Volume: 4 Suppl D

    Topics: Adrenergic beta-Antagonists; Alprenolol; Atenolol; Hemodynamics; Humans; Hypertension; Metoprolol; Pindolol; Propanolamines; Time Factors; Timolol

1983
Beta-adrenergic receptors in ciliary processes of the rabbit.
    Investigative ophthalmology & visual science, 1980, Volume: 19, Issue:2

    Topics: Adenylyl Cyclases; Alprenolol; Animals; Cell Membrane; Ciliary Body; Epinephrine; Isoproterenol; Male; Phentolamine; Pindolol; Propranolol; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, beta; Timolol

1980
Relationship between amount of beta-blockers permeating through the stratum corneum and skin irritation after application of beta-blocker adhesive patches to guinea pig skin.
    Biological & pharmaceutical bulletin, 1997, Volume: 20, Issue:4

    Topics: Acebutolol; Administration, Cutaneous; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Dermatitis, Irritant; Guinea Pigs; Male; Oxprenolol; Skin; Skin Absorption; Timolol

1997
Evaluation of the immobilized artificial membrane phosphatidylcholine. Drug discovery column for high-performance liquid chromatographic screening of drug-membrane interactions.
    Journal of chromatography. A, 1998, Mar-27, Volume: 800, Issue:2

    Topics: Acebutolol; Acetonitriles; Adrenergic beta-Antagonists; Alprenolol; Aniline Compounds; Atenolol; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Membranes, Artificial; Metoprolol; Models, Chemical; Osmolar Concentration; Oxprenolol; Phosphatidylcholines; Pindolol; Propranolol; Reproducibility of Results; Timolol

1998
In vitro permeability of eight beta-blockers through Caco-2 monolayers utilizing liquid chromatography/electrospray ionization mass spectrometry.
    Journal of mass spectrometry : JMS, 1998, Volume: 33, Issue:7

    Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Atenolol; Biological Availability; Caco-2 Cells; Cell Membrane Permeability; Chromatography, Liquid; Epithelial Cells; Humans; Intestinal Absorption; Intestinal Mucosa; Mass Spectrometry; Metoprolol; Molecular Structure; Oxprenolol; Pindolol; Propranolol; Research Design; Timolol

1998
1H and 13C NMR characteristics of β-blockers.
    Magnetic resonance in chemistry : MRC, 2011, Volume: 49, Issue:5

    Topics: Acebutolol; Acids; Adrenergic beta-Antagonists; Alkalies; Alprenolol; Atenolol; Carbazoles; Carbon Isotopes; Carvedilol; Nuclear Magnetic Resonance, Biomolecular; Pindolol; Propanolamines; Propranolol; Protons; Timolol

2011
Ligand-dependent perturbation of the conformational ensemble for the GPCR β2 adrenergic receptor revealed by HDX.
    Structure (London, England : 1993), 2011, Oct-12, Volume: 19, Issue:10

    Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Alprenolol; Binding Sites; Clenbuterol; Deuterium Exchange Measurement; Humans; Hydrogen Bonding; Ligands; Mass Spectrometry; Membranes; Peptides; Propanolamines; Protein Binding; Protein Stability; Protein Structure, Tertiary; Receptors, Adrenergic, beta-2; Timolol

2011