Page last updated: 2024-08-22

tiletamine hydrochloride and thiazoles

tiletamine hydrochloride has been researched along with thiazoles in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19905 (18.52)18.7374
1990's9 (33.33)18.2507
2000's7 (25.93)29.6817
2010's3 (11.11)24.3611
2020's3 (11.11)2.80

Authors

AuthorsStudies
Harrison, RA; Roldan, ER1
Foreman, JC; Hayes, NA; McLeod, J1
de Nucci, G; Mitchell, JA; Vane, JR; Warner, TD1
Boarder, MR; Jones, JA; Owen, PJ1
Dickinson, KE; Hirschowitz, BI; Hokin, LE; Pruitt, RE; Sekar, MC1
Dunn, WD; Nadler, J; Natarajan, R; Stern, N1
Cantwell, ME; Foreman, JC1
Burch, RM1
Dale, MM; Penfield, A1
Dale, MM; Muid, RE; Twomey, B1
Dale, MM; Muid, RE; Penfield, A1
Acamovic, F; Mackie, SC; Morrison, KS; Palmer, RM; Thompson, MG1
Burt, RP; Chapple, CR; Marshall, I1
Pagano, RE; Salman, M1
Ascher-Landsberg, J; Phillippe, M; Saunders, T1
Chakrabarti, R; Kumar, S1
Berry, JM; Bradshaw, TD; Burger, AM; Seaton, A; Stevens, MF; Wang, B; Wells, G; Westwell, AD1
Bradshaw, TD; Carmichael, J; Martin, SG; Mukherjee, A; Stevens, MF; Westwell, AD1
Bailey, K; Bradshaw, TD; Chew, EH; Cookson, J; Harris, E; Laughton, CA; Matthews, CS; Monks, A; Shah, M; Stevens, MF; Wells, G; Westwell, AD1
Bradshaw, TD; Chew, EH; Hagen, T; Matthews, CS; McCarroll, AJ; Stevens, MF; Westwell, AD; Zhang, J1
Alcaro, S; Bolasco, A; Carradori, S; Chimenti, F; Chimenti, P; Cirilli, R; Ferretti, R; Granese, A; La Torre, F; Maccioni, E; Orallo, F; Ortuso, F; Secci, D; Yáñez, M1
Chen, H; Huang, H; Jiang, H; Wu, W; Zhao, J1
Abbas, NS; Ahmed, EA1
Aydinok, Y; Berk, G; Cohen, AR; Giardina, PJ; Jeglinski, BI; Kuo, KH; Kwiatkowski, JL; Neufeld, EJ; Pietropaolo, K; Saliba, AN; Taher, AT; Viprakasit, V1
Abdo, NYM; Al-Darkazali, WN; Mohareb, RM1
Elmetwally, AM; Mohamed, AA; Mohareb, RM; Wardakhan, WW1
Alwan, ES; Ibrahim, RA; Mohareb, RM1

Trials

1 trial(s) available for tiletamine hydrochloride and thiazoles

ArticleYear
Safety and pharmacokinetics of the oral iron chelator SP-420 in β-thalassemia.
    American journal of hematology, 2017, Volume: 92, Issue:12

    Topics: Adolescent; Adult; beta-Thalassemia; Blood Transfusion; Cyclohexanones; Dihydropyridines; Dose-Response Relationship, Drug; Humans; Iron Chelating Agents; Kidney Diseases; Middle Aged; Siderophores; Thiazoles; Young Adult

2017

Other Studies

26 other study(ies) available for tiletamine hydrochloride and thiazoles

ArticleYear
The role of diacylglycerol in the exocytosis of the sperm acrosome. Studies using diacylglycerol lipase and diacylglycerol kinase inhibitors and exogenous diacylglycerols.
    The Biochemical journal, 1992, Feb-01, Volume: 281 ( Pt 3)

    Topics: Acrosome; Animals; Calcimycin; Calcium; Cyclohexanones; Diacylglycerol Kinase; Diglycerides; Exocytosis; Lipoprotein Lipase; Male; Neomycin; Phosphatidic Acids; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phosphotransferases; Pyrimidinones; Sheep; Spermatozoa; Thiazoles

1992
Effect of 12-O-tetradecanoylphorbol-13-acetate (TPA) on substance P-induced histamine release from rat peritoneal mast cells.
    Agents and actions, 1990, Volume: 30, Issue:1-2

    Topics: Animals; Ascitic Fluid; Calcium; Cyclohexanones; Female; Histamine Release; In Vitro Techniques; Male; Mast Cells; Platelet Activating Factor; Pyrimidinones; Rats; Rats, Inbred Strains; Substance P; Tetradecanoylphorbol Acetate; Thiazoles

1990
Alkaline buffers release EDRF from bovine cultured aortic endothelial cells.
    British journal of pharmacology, 1991, Volume: 103, Issue:2

    Topics: Animals; Arginine; Buffers; Cattle; Cells, Cultured; Cyclohexanones; Endothelium, Vascular; Epoprostenol; Hydrogen-Ion Concentration; Lipoprotein Lipase; Nitric Oxide; omega-N-Methylarginine; Platelet Activating Factor; Pyrimidinones; Thiazoles

1991
Influence of phorbol esters, and diacylglycerol kinase and lipase inhibitors on noradrenaline release and phosphoinositide hydrolysis in chromaffin cells.
    British journal of pharmacology, 1990, Volume: 101, Issue:3

    Topics: Adrenal Medulla; Animals; Cattle; Cyclohexanones; Diacylglycerol Kinase; Hydrolysis; In Vitro Techniques; Lipoprotein Lipase; Norepinephrine; Phosphatidylinositols; Phosphotransferases; Pyrimidinones; Tetradecanoylphorbol Acetate; Thiazoles

1990
Muscarinic receptor antagonist activity of diacylglycerol lipase and kinase inhibitors.
    Biochemical pharmacology, 1990, Jun-15, Volume: 39, Issue:12

    Topics: Animals; Brain; Cells, Cultured; Cyclic GMP; Cyclohexanes; Cyclohexanones; Guinea Pigs; Heart; Lipoprotein Lipase; Myocardium; N-Methylscopolamine; Pancreas; Parasympatholytics; Platelet Activating Factor; Pyrimidinones; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Thiazoles; Tritium

1990
Key role of diacylglycerol-mediated 12-lipoxygenase product formation in angiotensin II-induced aldosterone synthesis.
    Molecular and cellular endocrinology, 1990, Aug-20, Volume: 72, Issue:2

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Aldosterone; Angiotensin II; Animals; Arachidonate 12-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Cyclohexanones; Diacylglycerol Kinase; Diglycerides; Hydroxyeicosatetraenoic Acids; Lipoprotein Lipase; Male; Phosphotransferases; Pyrimidinones; Rats; Rats, Inbred Strains; Thiazoles; Zona Glomerulosa

1990
The actions of inhibitors of diacylglycerol kinase and diacylglycerol lipase on histamine release from rat peritoneal mast cells.
    British journal of pharmacology, 1987, Volume: 92, Issue:3

    Topics: Animals; Cyclohexanones; Diacylglycerol Kinase; Histamine Release; In Vitro Techniques; Lipoprotein Lipase; Male; Mast Cells; Peritoneal Cavity; Phosphotransferases; Pyrimidinones; Rats; Rats, Inbred Strains; Thiazoles

1987
Diacylglycerol in the synergy of bradykinin and thrombin stimulation of prostaglandin synthesis.
    European journal of pharmacology, 1989, Sep-01, Volume: 168, Issue:1

    Topics: Animals; Bradykinin; Cyclohexanones; Diacylglycerol Kinase; Diglycerides; Dinoprostone; Drug Synergism; Fibroblasts; Glycerides; Mice; Mice, Inbred BALB C; Phosphotransferases; Pyrimidinones; Thiazoles; Thrombin; Time Factors

1989
Comparison of the effects of indomethacin, RHC80267 and R59022 on superoxide production by 1,oleoyl-2,acetyl glycerol and A23187 in human neutrophils.
    British journal of pharmacology, 1987, Volume: 92, Issue:1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Calcimycin; Cyclohexanes; Cyclohexanones; Diglycerides; Glycerides; Humans; In Vitro Techniques; Indomethacin; Kinetics; Neutrophils; Platelet Activating Factor; Pyrimidinones; Superoxides; Thiazoles

1987
The effect of inhibition of both diacylglycerol metabolism and phospholipase A2 activity on superoxide generation by human neutrophils.
    FEBS letters, 1988, Jul-04, Volume: 234, Issue:1

    Topics: Cyclohexanones; Diacylglycerol Kinase; Humans; Indomethacin; Lipoprotein Lipase; Meclofenamic Acid; Neutrophils; Phospholipases; Phospholipases A; Phospholipases A2; Phosphotransferases; Pyrimidinones; Sodium Fluoride; Superoxides; Thiazoles

1988
The diacylglycerol kinase inhibitor, R59022, enhances the superoxide generation from human neutrophils induced by stimulation of fMet-Leu-Phe, IgG and C3b receptors.
    Biochemical and biophysical research communications, 1987, Mar-13, Volume: 143, Issue:2

    Topics: Cyclohexanones; Diacylglycerol Kinase; Diglycerides; Humans; In Vitro Techniques; Lipoprotein Lipase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphotransferases; Protein Kinase C; Pyrimidinones; Receptors, Complement; Receptors, Complement 3b; Receptors, Fc; Receptors, Formyl Peptide; Receptors, Immunologic; Superoxides; Thiazoles

1987
Arachidonate activation of protein kinase C may be involved in the stimulation of protein synthesis by insulin in L6 myoblasts.
    Bioscience reports, 1993, Volume: 13, Issue:6

    Topics: Animals; Arachidonic Acid; Cell Line; Cyclohexanones; Cyclooxygenase Inhibitors; Diglycerides; Enzyme Activation; Indoles; Insulin; Lipoprotein Lipase; Muscle Proteins; Muscles; Protein Kinase C; Pyrimidinones; Rats; Thiazoles

1993
The role of diacylglycerol and activation of protein kinase C in alpha 1A-adrenoceptor-mediated contraction to noradrenaline of rat isolated epididymal vas deferens.
    British journal of pharmacology, 1996, Volume: 117, Issue:1

    Topics: Animals; Calcium; Carcinogens; Cyclohexanones; Diglycerides; Lipoprotein Lipase; Male; Naphthalenes; Norepinephrine; Phorbol 12,13-Dibutyrate; Platelet Activating Factor; Protein Kinase C; Pyrimidinones; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Staurosporine; Thiazoles; Vas Deferens

1996
Use of a fluorescent analog of CDP-DAG in human skin fibroblasts: characterization of metabolism, distribution, and application to studies of phosphatidylinositol turnover.
    Journal of lipid research, 1997, Volume: 38, Issue:3

    Topics: 4-Chloro-7-nitrobenzofurazan; Cells, Cultured; Chromatography, Thin Layer; Cyclohexanones; Cytidine Diphosphate Diglycerides; Enzyme Inhibitors; Fibroblasts; Fluorescent Dyes; Humans; Interleukin-1; Lipoprotein Lipase; Membrane Lipids; Microscopy, Fluorescence; Oleic Acid; Palmitic Acid; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylinositols; Platelet-Derived Growth Factor; Propranolol; Pyrimidinones; Thiazoles

1997
The role of diacylglycerol as a modulator of oxytocin-stimulated phasic contractions in myometrium from pregnant and nonpregnant rats.
    American journal of obstetrics and gynecology, 2000, Volume: 182, Issue:4

    Topics: Animals; Cyclohexanones; Diacylglycerol Kinase; Diglycerides; Enzyme Inhibitors; Female; Lipoprotein Lipase; Myometrium; Oxytocin; Pregnancy; Pregnancy, Animal; Pyrimidinones; Rats; Rats, Sprague-Dawley; Reference Values; Thiazoles; Uterine Contraction

2000
Diacylglycerol mediates the T-cell receptor-driven Ca(2+) influx in T cells by a novel mechanism independent of protein kinase C activation.
    Journal of cellular biochemistry, 2000, Volume: 78, Issue:2

    Topics: Animals; Calcium Signaling; Cyclohexanones; Diglycerides; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Lipoprotein Lipase; Mice; Mice, Inbred BALB C; Naphthalenes; Nickel; Protein Kinase C; Pyrimidinones; Receptors, Antigen, T-Cell; T-Lymphocytes; Thiazoles

2000
4-Substituted 4-hydroxycyclohexa-2,5-dien-1-ones with selective activities against colon and renal cancer cell lines.
    Journal of medicinal chemistry, 2003, Feb-13, Volume: 46, Issue:4

    Topics: Algorithms; Animals; Antineoplastic Agents; Benzothiazoles; Colonic Neoplasms; Computer Simulation; Cyclohexanes; Cyclohexanones; Drug Screening Assays, Antitumor; Humans; Kidney Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Structure-Activity Relationship; Thiazoles; Transplantation, Heterologous; Tumor Cells, Cultured

2003
Cytotoxic and antiangiogenic activity of AW464 (NSC 706704), a novel thioredoxin inhibitor: an in vitro study.
    British journal of cancer, 2005, Jan-31, Volume: 92, Issue:2

    Topics: Antineoplastic Agents; Benzothiazoles; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Cyclohexanones; Endothelial Cells; Enzyme-Linked Immunosorbent Assay; Fibroblast Growth Factor 2; Fibroblasts; Humans; Hypoxia; In Vitro Techniques; Neovascularization, Pathologic; Thiazoles

2005
Elucidation of thioredoxin as a molecular target for antitumor quinols.
    Cancer research, 2005, May-01, Volume: 65, Issue:9

    Topics: Amino Acid Sequence; Antineoplastic Agents; Benzothiazoles; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; Colonic Neoplasms; Cyclohexanones; Drug Screening Assays, Antitumor; Humans; Hydroquinones; Insulin; Mass Spectrometry; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; Sulfones; Thiazoles; Thioredoxins

2005
Antitumor quinols: role of glutathione in modulating quinol-induced apoptosis and identification of putative cellular protein targets.
    Biochemical and biophysical research communications, 2006, Jul-21, Volume: 346, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Benzothiazoles; Caspase 3; Caspases; Cell Line, Tumor; Cyclohexanones; Glutathione; Humans; Hydroquinones; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Sulfones; Thiazoles

2006
Synthesis, stereochemical identification, and selective inhibitory activity against human monoamine oxidase-B of 2-methylcyclohexylidene-(4-arylthiazol-2-yl)hydrazones.
    Journal of medicinal chemistry, 2008, Aug-28, Volume: 51, Issue:16

    Topics: Chromatography, High Pressure Liquid; Cyclohexanones; Humans; Hydrazones; Inhibitory Concentration 50; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Stereoisomerism; Thermodynamics; Thiazoles; Thiosemicarbazones

2008
Metal-free synthesis of 2-aminobenzothiazoles via aerobic oxidative cyclization/dehydrogenation of cyclohexanones and thioureas.
    Organic letters, 2013, Jun-07, Volume: 15, Issue:11

    Topics: Benzothiazoles; Catalysis; Cyclization; Cyclohexanones; Iodine; Metals; Molecular Structure; Oxidation-Reduction; Oxygen; Thiazoles; Thiourea

2013
New approaches for the synthesis and cytotoxicity of thiazoles derived from cyclohexanone.
    Acta chimica Slovenica, 2014, Volume: 61, Issue:4

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cyclohexanones; Humans; Isothiocyanates; Molecular Structure; Structure-Activity Relationship; Sulfur; Thiazoles

2014
Heterocyclization of 2-Arylidenecyclohexan-1,3-dione: Synthesis of Thiophene, Thiazole, and Isoxazole Derivatives with Potential Antitumor Activities.
    Anti-cancer agents in medicinal chemistry, 2020, Volume: 20, Issue:3

    Topics: Acetates; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cyclization; Cyclohexanones; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Isoxazoles; Molecular Structure; Nitriles; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Proto-Oncogene Proteins c-pim-1; src-Family Kinases; Structure-Activity Relationship; Thiazoles; Thiophenes

2020
The Uses of Dimedone for the Synthesis of Thiophene, Thiazole and Annulated Derivatives with Antitumor, Pim-1 Kinase Inhibitions, PAINS Evaluations and Molecular Docking.
    Anti-cancer agents in medicinal chemistry, 2021, 10-28, Volume: 21, Issue:16

    Topics: Antineoplastic Agents; Cell Line; Cell Proliferation; Cyclohexanones; Drug Screening Assays, Antitumor; Humans; Molecular Docking Simulation; Molecular Structure; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-pim-1; Thiazoles; Thiophenes

2021
Multi-component Reactions of Cyclohexan-1,3-diketones to Produce Fused Pyran Derivatives with Antiproliferative Activities and Tyrosine Kinases and Pim-1 Kinase Inhibitions.
    Acta chimica Slovenica, 2021, Volume: 68, Issue:1

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cyclohexanones; Drug Screening Assays, Antitumor; Humans; Hydrazones; Molecular Structure; Protein Kinase Inhibitors; Structure-Activity Relationship; Thiazoles; Thiophenes; Xanthenes

2021