tiglyl-coenzyme-a and tiglylglycine

tiglyl-coenzyme-a has been researched along with tiglylglycine* in 1 studies

Other Studies

1 other study(ies) available for tiglyl-coenzyme-a and tiglylglycine

Article	Year
The identification of (E)-2-methylglutaconic acid, a new isoleucine metabolite, in the urine of patients with beta-ketothiolase deficiency, propionic acidaemia and methylmalonic acidaemia. Biomedical mass spectrometry, 1982, Volume: 9, Issue:1 The identification of (E)-2-methylglutaconic acid, a 'new' metabolite of isoleucine, is described. The substance was detected in urine samples from patients with propionic acidaemia, methylmalonic acidaemia and so-called beta-ketothiolase deficiency; in the majority of cases together with N-tiglylglycine. (E)-2-Methylglutaconic acid is thought to be the end product of the 3-methylcrotonyl-CoA carboxylase-catalysed carboxylation of tiglyl-CoA. Prerequisites for the quantitative gas chromatographic analysis of the unstable 2- (and 3-) methyl-glutaconic acid ditrimethylsilyl ester are given. Topics: Acetyl-CoA C-Acyltransferase; Acyl Coenzyme A; Acyltransferases; Amino Acid Metabolism, Inborn Errors; Gas Chromatography-Mass Spectrometry; Glutarates; Glycine; Humans; Isoleucine; Malonates; Methylmalonic Acid; Propionates; Reference Values	1982

Article

Year

The identification of (E)-2-methylglutaconic acid, a new isoleucine metabolite, in the urine of patients with beta-ketothiolase deficiency, propionic acidaemia and methylmalonic acidaemia.

Biomedical mass spectrometry, 1982, Volume: 9, Issue:1

The identification of (E)-2-methylglutaconic acid, a 'new' metabolite of isoleucine, is described. The substance was detected in urine samples from patients with propionic acidaemia, methylmalonic acidaemia and so-called beta-ketothiolase deficiency; in the majority of cases together with N-tiglylglycine. (E)-2-Methylglutaconic acid is thought to be the end product of the 3-methylcrotonyl-CoA carboxylase-catalysed carboxylation of tiglyl-CoA. Prerequisites for the quantitative gas chromatographic analysis of the unstable 2- (and 3-) methyl-glutaconic acid ditrimethylsilyl ester are given.

Topics: Acetyl-CoA C-Acyltransferase; Acyl Coenzyme A; Acyltransferases; Amino Acid Metabolism, Inborn Errors; Gas Chromatography-Mass Spectrometry; Glutarates; Glycine; Humans; Isoleucine; Malonates; Methylmalonic Acid; Propionates; Reference Values

1982