ticrynafen has been researched along with thiophenes in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amar, C; Dansette, PM; Mansuy, D; Pons, C; Smith, C | 1 |
| Andronik, V; Dansette, PM; Mansuy, D; Neau, E | 1 |
| Dansette, PM; Dijols, S; Mansuy, D; Minoletti, C | 1 |
| Gramec, D; Peterlin Mašič, L; Sollner Dolenc, M | 1 |
1 review(s) available for ticrynafen and thiophenes
| Article | Year |
|---|---|
Bioactivation potential of thiophene-containing drugs.
Topics: Antidepressive Agents; Cytochrome P-450 Enzyme System; Depression; Duloxetine Hydrochloride; Hepatitis; Humans; Platelet Aggregation Inhibitors; Thiophenes; Ticrynafen | 2014 |
3 other study(ies) available for ticrynafen and thiophenes
| Article | Year |
|---|---|
Oxidative activation of the thiophene ring by hepatic enzymes. Hydroxylation and formation of electrophilic metabolites during metabolism of tienilic acid and its isomer by rat liver microsomes.
Topics: Animals; Biotransformation; Chromatography, High Pressure Liquid; Glycolates; Hydroxylation; Isomerism; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Phenobarbital; Protein Binding; Rats; Rats, Inbred Strains; Thiophenes; Ticrynafen | 1990 |
Hydroxylation of the thiophene ring by hepatic monooxygenases. Evidence for 5-hydroxylation of 2-aroylthiophenes as a general metabolic pathway using a simple UV-visible assay.
Topics: Animals; Cytochrome P-450 Enzyme System; Hydroxylation; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Oxygenases; Rats; Rats, Inbred Strains; Spectrophotometry; Spectrophotometry, Ultraviolet; Thiophenes; Ticrynafen | 1990 |
Comparison of the substrate specificities of human liver cytochrome P450s 2C9 and 2C18: application to the design of a specific substrate of CYP 2C18.
Topics: Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Hydroxylation; Liver; Mixed Function Oxygenases; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Recombinant Proteins; Spectrophotometry, Ultraviolet; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Structure-Activity Relationship; Substrate Specificity; Thiophenes; Ticrynafen | 1999 |