Page last updated: 2024-08-23

ticrynafen and hydrochlorothiazide

ticrynafen has been researched along with hydrochlorothiazide in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199028 (87.50)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Agnew, MN; Caldwell, SR; Kitzen, JM; Ong, HH; Profitt, JA; Ress, RJ; Tegeler, JJ; Wilker, JC1
Bunnell, PR; Crowley, SR; Dodge, PW; Fung, AK; Pariza, RJ; Parks, JA; Pernet, AG; Plattner, JJ1
Cragoe, EJ; Fanelli, GM; Hoffman, WF; Novello, FC; Springer, JP; Watson, LS; Woltersdorf, OW1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Andersson, O; Berglund, G; Hansson, L1
Freis, ED2
Beg, MA; Okun, R1
Beg, MA; Noble, RE1
Beg, MA; Ragland, R1
Fishman, AP; Weber, KT1
Jain, AK; McMahon, FG; Ryan, JR1
Covi, G; di Perri, T; Gouère, P; Lechi, A; Locatelli, F; Messa, GL; Pedrini, L; Pincella, G; Ponticelli, C; Recchia, M; Redaelli, B; Rivolta, E1
Covi, G; Danti, G; Lechi, A; Pedrolli, E; Pomari, S; Riva, AD1
Sherrard, DJ1
Singer, K1
Chrysant, SG; De Carvalho, JG; Dunn, FG; Frohlich, ED1
Agabiti-Rosei, E; Alicandri, C; Corea, L; Fariello, R; Muiesan, G; Oldoni, T1
Daveloose, D; Labeyrie, E; Leterrier, F; Molle, D; Salesse, R; Viret, J1
Ferrara, LA; Galletti, F; Siani, A; Strazzullo, P1
Rosendorff, C1
Gillies, A; Morgan, TO; Myers, JB; Waga, S1
Amery, A; Fagard, R; Lijnen, P; Staessen, J1
Denham, I; Emmerson, BT; Ravenscroft, PJ; Renshaw, PJ; Schey, S1
de Torrenté, A1
Tse, TF; Wong, CM1
Berger, L; Kaung, C; Sarkozi, L; Yü, T1
Badimón, JJ; Badimón, L; Bruseghini, L; Padró, T; Villaverde, CA1

Reviews

1 review(s) available for ticrynafen and hydrochlorothiazide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

14 trial(s) available for ticrynafen and hydrochlorothiazide

ArticleYear
Tienilic acid in mild to moderate hypertension.
    Postgraduate medical journal, 1979, Volume: 55 Suppl 3

    Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Glycolates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Ticrynafen; Uric Acid

1979
A double-blind study of tienilic acid with two year follow-up of patients with mild to moderate essential hypertension.
    Postgraduate medical journal, 1979, Volume: 55 Suppl 3

    Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Follow-Up Studies; Glycolates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Ticrynafen; Uric Acid

1979
Long-term usage of tienilic acid in essential hypertension.
    Postgraduate medical journal, 1979, Volume: 55 Suppl 3

    Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Glycolates; Humans; Hydrochlorothiazide; Hypertension; Ticrynafen; Time Factors; Uric Acid

1979
Safety of tienilic acid.
    Postgraduate medical journal, 1979, Volume: 55 Suppl 3

    Topics: Clinical Trials as Topic; Glycolates; Heart Failure; Humans; Hydrochlorothiazide; Hypertension; Kidney Diseases; Probenecid; Ticrynafen; Uric Acid

1979
Tienilic acid, a uricosuric diuretic, in the treatment of heart failure.
    Postgraduate medical journal, 1979, Volume: 55 Suppl 3

    Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Glycolates; Heart Failure; Humans; Hydrochlorothiazide; Male; Middle Aged; Ticrynafen

1979
The hypouricaemic effect of tienilic acid: experience in patients with hyperuricaemia.
    Postgraduate medical journal, 1979, Volume: 55 Suppl 3

    Topics: Adult; Aged; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus; Double-Blind Method; Drug Administration Schedule; Female; Glycolates; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Probenecid; Ticrynafen; Uric Acid

1979
Double-blind assessment of tienilic acid in essential hypertension.
    Postgraduate medical journal, 1979, Volume: 55 Suppl 3

    Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Glycolates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Random Allocation; Ticrynafen; Uric Acid

1979
Multicentre comparative trial of tienilic acid and hydrochlorothiazide in hypertensive patients.
    European journal of clinical pharmacology, 1979, Volume: 16, Issue:5

    Topics: Adolescent; Adult; Aged; Blood Cell Count; Blood Glucose; Clinical Trials as Topic; Electrolytes; Female; Glycolates; Humans; Hydrochlorothiazide; Hypertension; Kidney; Lipids; Liver; Male; Middle Aged; Ticrynafen; Uric Acid

1979
An evaluation of tienilic acid, a new diuretic uricosuric agent, in the therapy of arterial hypertension.
    Clinical science (London, England : 1979), 1979, Volume: 57 Suppl 5

    Topics: Adolescent; Adult; Aged; Blood Glucose; Blood Pressure; Cholesterol; Clinical Trials as Topic; Creatinine; Double-Blind Method; Electrolytes; Female; Glycolates; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Posture; Ticrynafen; Triglycerides; Uric Acid

1979
[Tienilic acid in the treatment of arterial hypertension and congestive cardiac insufficiency].
    Giornale italiano di cardiologia, 1979, Volume: 9, Issue:12

    Topics: Adult; Aged; Diuresis; Drug Evaluation; Female; Glycolates; Heart Failure; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Placebos; Potassium; Ticrynafen; Triglycerides; Uric Acid

1979
Long term treatment with tienilic acid or thiazides: comparison of antihypertensive and metabolic effects.
    European journal of clinical pharmacology, 1983, Volume: 25, Issue:6

    Topics: Adult; Amiloride; Blood Pressure; Female; Glycolates; Humans; Hydrochlorothiazide; Hypertension; Liver Function Tests; Male; Middle Aged; Potassium; Pyrazines; Random Allocation; Ticrynafen; Uric Acid

1983
The treatment of mild to moderate essential hypertension with tienilic acid (ticrynafen).
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1980, Jun-28, Volume: 57, Issue:26

    Topics: Clinical Trials as Topic; Double-Blind Method; Female; Glycolates; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Ticrynafen; Uric Acid

1980
Effect of tienilic acid and amiloride in healthy volunteers and in hypertensives with normal renal function.
    British journal of clinical pharmacology, 1980, Volume: 10, Issue:4

    Topics: Adolescent; Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Diuretics; Drug Therapy, Combination; Electrolytes; Female; Glycolates; Humans; Hydrochlorothiazide; Hypertension; Kidney; Male; Middle Aged; Pyrazines; Ticrynafen; Uric Acid

1980
Ticrynafen and hydrochlorothiazide. A comparison in hypertensive patients with renal impairment.
    European journal of clinical pharmacology, 1982, Volume: 22, Issue:3

    Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Glycolates; Humans; Hydrochlorothiazide; Hypertension, Renal; Kidney Diseases; Male; Middle Aged; Ticrynafen

1982

Other Studies

17 other study(ies) available for ticrynafen and hydrochlorothiazide

ArticleYear
[(6,7-Dichlorobenzo[b]thien-5-yl)oxy]acetic acids and 1,1-dioxides. 1. A structurally novel class of diuretics with hypotensive activity.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:12

    Topics: Acetates; Animals; Antihypertensive Agents; Diuretics; Dogs; Female; Glycolates; Male; Mice; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Structure-Activity Relationship; Thiophenes

1987
Substituted 5,6-dihydrofuro[3,2-f]-1,2-benzisoxazole-6-carboxylic acids: high-ceiling diuretics with uricosuric activity.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:8

    Topics: Animals; Chlorides; Diuretics; Dogs; Dose-Response Relationship, Drug; Furans; Haplorhini; Isoxazoles; Mice; Models, Molecular; Natriuresis; Oxazoles; Potassium; Rats; Sodium; Stereoisomerism; Structure-Activity Relationship; Uricosuric Agents

1984
(Acylaryloxy)acetic acid diuretics. 3. 2,3-Dihydro-5-acyl-2-benzofurancarboxylic acids, a new class of uricosuric diuretics.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:7

    Topics: Animals; Benzofurans; Chemical Phenomena; Chemistry; Diuretics; Dogs; Pan troglodytes; Rats; Species Specificity; Structure-Activity Relationship; Uricosuric Agents; X-Ray Diffraction

1981
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Treatment of hypertension: state of the art in 1979.
    Clinical science (London, England : 1979), 1979, Volume: 57 Suppl 5

    Topics: Adrenergic alpha-Antagonists; Angiotensin II; Glycolates; Humans; Hydrochlorothiazide; Hypertension; Minoxidil; Pyrimidines; Reserpine; Saralasin; Ticrynafen; United States

1979
Relative costs of ticrynafen and thiazides.
    The New England journal of medicine, 1979, Dec-13, Volume: 301, Issue:24

    Topics: Costs and Cost Analysis; Glycolates; Humans; Hydrochlorothiazide; Patient Compliance; Ticrynafen

1979
Relative costs of ticrynafen and thiazides.
    The New England journal of medicine, 1979, Dec-13, Volume: 301, Issue:24

    Topics: Costs and Cost Analysis; Glycolates; Humans; Hydrochlorothiazide; Hypertension; Ticrynafen

1979
Antihypertensive and renal effects of tienilic acid.
    Postgraduate medical journal, 1979, Volume: 55 Suppl 3

    Topics: Glycolates; Humans; Hydrochlorothiazide; Hypertension; Kidney; Male; Potassium; Ticrynafen; Uric Acid

1979
[Mechanism of action of benzothiadiazides in arterial hypertension: the energetic theory].
    Annales de medecine interne, 1982, Volume: 133, Issue:8

    Topics: Adenylyl Cyclase Inhibitors; Animals; Chlorthalidone; Columbidae; Cyclic AMP; Diuretics; Energy Metabolism; Erythrocyte Membrane; Humans; Hydrochlorothiazide; Hypertension; Indapamide; Ticrynafen

1982
Effect of chronic diuretic treatment on the plasma renin-angiotensin-aldosterone system in essential hypertension.
    British journal of clinical pharmacology, 1981, Volume: 12, Issue:3

    Topics: Adult; Aldosterone; Angiotensins; Diuretics; Electrolytes; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Renin; Ticrynafen; Time Factors

1981
[Tienilic acid, hyperuricemia and kidney function].
    Schweizerische medizinische Wochenschrift, 1981, Mar-14, Volume: 111, Issue:11

    Topics: Aged; Creatinine; Female; Furosemide; Glycolates; Heart Failure; Humans; Hydrochlorothiazide; Kidney Function Tests; Male; Middle Aged; Ticrynafen; Uric Acid

1981
Comparison of the metabolic and antihypertensive properties of tienilic acid and hydrochlorothiazide.
    The Medical journal of Australia, 1981, Mar-07, Volume: 1, Issue:5

    Topics: Adult; Aged; Double-Blind Method; Female; Glycolates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Ticrynafen

1981
Effects of diuretics on urate and calcium excretion.
    Archives of internal medicine, 1981, Volume: 141, Issue:7

    Topics: Adult; Aged; Calcium; Chlorides; Furosemide; Glycolates; Gout; Humans; Hydrochlorothiazide; Middle Aged; Phosphorus; Potassium; Sodium; Ticrynafen; Uric Acid

1981
[Pharmacological aspects of tienilic acid].
    Archivos de farmacologia y toxicologia, 1981, Volume: 7, Issue:1

    Topics: Animals; Blood Chemical Analysis; Diuresis; Female; Glycolates; Hydrochlorothiazide; Rats; Rats, Inbred Strains; Ticrynafen

1981
Tienilic acid, an unusual diuretic.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1980, Jun-28, Volume: 57, Issue:26

    Topics: Diuretics; Glycolates; Humans; Hydrochlorothiazide; Infant, Newborn; Ticrynafen; Uric Acid

1980