ticlopidine has been researched along with efavirenz in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 6 (75.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Astuccio, AV; Obach, RS; Walsky, RL | 1 |
| Desta, Z; Guo, Y; Ogburn, ET; Xu, C | 1 |
| Bae, SK; Desta, Z; Flockhart, DA; Jiang, F; Kim, HS; Lee, SS; Liu, KH; Shin, JG; Shon, JH; Yeo, CW | 1 |
| Abdelhady, AM; Desta, Z; Jiang, F; Overholser, BR; Shin, JG; Yeo, CW | 1 |
1 review(s) available for ticlopidine and efavirenz
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 trial(s) available for ticlopidine and efavirenz
| Article | Year |
|---|---|
Effects of clopidogrel and itraconazole on the disposition of efavirenz and its hydroxyl metabolites: exploration of a novel CYP2B6 phenotyping index.
Topics: Alkynes; Anti-HIV Agents; Antifungal Agents; Aryl Hydrocarbon Hydroxylases; Benzoxazines; Clopidogrel; Cross-Over Studies; Cyclopropanes; Cytochrome P-450 CYP2B6; Genotype; Humans; Hydroxylation; Itraconazole; Male; Oxidoreductases, N-Demethylating; Phenotype; Platelet Aggregation Inhibitors; Ticlopidine | 2013 |
Population pharmacogenetic-based pharmacokinetic modeling of efavirenz, 7-hydroxy- and 8-hydroxyefavirenz.
Topics: Adult; Algorithms; Alkynes; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzoxazines; Chromatography, High Pressure Liquid; Clopidogrel; Computer Simulation; Cross-Over Studies; Cyclopropanes; Cytochrome P-450 Enzyme System; DNA; Drug Interactions; Humans; Male; Models, Biological; Pharmacogenetics; Population; Reverse Transcriptase Inhibitors; Tandem Mass Spectrometry; Ticlopidine; Treatment Outcome; Young Adult | 2014 |
5 other study(ies) available for ticlopidine and efavirenz
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Evaluation of 227 drugs for in vitro inhibition of cytochrome P450 2B6.
Topics: Algorithms; Alkynes; Antidepressive Agents, Second-Generation; Antifungal Agents; Area Under Curve; Benzoxazines; Bupropion; Clopidogrel; Clotrimazole; Cyclopropanes; Cytochrome P-450 CYP2B6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Itraconazole; Kinetics; Microsomes, Liver; Molecular Structure; Oxazines; Platelet Aggregation Inhibitors; Raloxifene Hydrochloride; Reverse Transcriptase Inhibitors; Selective Estrogen Receptor Modulators; Selective Serotonin Reuptake Inhibitors; Sertraline; Ticlopidine; Xenobiotics | 2006 |
Effects of the CYP2B6*6 allele on catalytic properties and inhibition of CYP2B6 in vitro: implication for the mechanism of reduced efavirenz metabolism and other CYP2B6 substrates in vivo.
Topics: Alkynes; Alleles; Aryl Hydrocarbon Hydroxylases; Benzoxazines; Biotransformation; Bupropion; Catalysis; Clopidogrel; Cyclopropanes; Cytochrome P-450 CYP2B6; Cytochromes b5; Enzyme Inhibitors; Humans; Hydroxylation; In Vitro Techniques; Kinetics; Microsomes, Liver; Oxidoreductases, N-Demethylating; Pyrimidines; Substrate Specificity; Ticlopidine; Triazoles; Voriconazole | 2012 |