Compounds > ticlopidine
Page last updated: 2024-08-16

ticlopidine and cyclosporine

ticlopidine has been researched along with cyclosporine in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.55)18.2507
2000's9 (40.91)29.6817
2010's11 (50.00)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Barthelemy, JC; Batt, AM; Boissonnat, P; Brouard, R; de Lorgeril, M; Delaye, J; Perroux, V; Salen, P; Serres, E1
Liebman, HA; Murata-Collins, JL; Pullarkat, VA; Rho, H1
de Cos, MA; López-Lázaro, L; Verdejo, A; Zubimendi, JA1
Chinnakotla, S; Fidler, ME; Hammeke, MD; Leone, JP; Tarantolo, S1
George, JN; Medina, PJ; Sipols, JM1
Ertorer, ME; Gokcel, A; Kocak, R; Savaş, L1
Ancarani, E; Feriozzi, S; Massimetti, C1
Bennett, C; Zakarija, A1
Burton, I; Burton, JR; Pearson, GJ1
Takahashi, R1
Jang, YP; Kim, HJ; Lee, JH; Lee, YJ; Oh, JH; Shin, YJ1
Lee, JH; Lee, YJ; Oh, JH; Shin, YJ1

Reviews

5 review(s) available for ticlopidine and cyclosporine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Ticlopidine-induced aplastic anemia: development of chromosomal abnormalities and response to immunosuppressive therapy.
    American journal of hematology, 2000, Volume: 63, Issue:3

    Topics: Aged; Aged, 80 and over; Anemia, Aplastic; Bone Marrow; Chromosome Aberrations; Chromosome Disorders; Cyclosporine; Dexamethasone; Fibrinolytic Agents; Humans; Immunosuppressive Agents; Male; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome

2000
Drug-associated thrombotic thrombocytopenic purpura-hemolytic uremic syndrome.
    Current opinion in hematology, 2001, Volume: 8, Issue:5

    Topics: Antibiotics, Antineoplastic; Clopidogrel; Cyclosporine; Hemolytic-Uremic Syndrome; Humans; Immunosuppressive Agents; Mitomycin; Muscle Relaxants, Central; Platelet Aggregation Inhibitors; Quinine; Ticlopidine

2001
Drug-induced thrombotic microangiopathy.
    Seminars in thrombosis and hemostasis, 2005, Volume: 31, Issue:6

    Topics: ADAM Proteins; ADAMTS13 Protein; Antibiotics, Antineoplastic; Cyclosporine; Endothelium, Vascular; Fibrinolytic Agents; Hemolytic-Uremic Syndrome; Humans; Immunosuppressive Agents; Mitomycin; Purpura, Thrombotic Thrombocytopenic; Quinine; Ticlopidine; Treatment Outcome

2005
[Drug-induced thrombotic thrombocytopenic purpura].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Oct-28, Volume: 65 Suppl 8

    Topics: Antirheumatic Agents; Aspirin; Cyclosporine; Diagnosis, Differential; Humans; Immunosuppressive Agents; Penicillamine; Plasma; Plasma Exchange; Platelet Aggregation Inhibitors; Prognosis; Purpura, Thrombotic Thrombocytopenic; Ticlopidine

2007

Trials

1 trial(s) available for ticlopidine and cyclosporine

ArticleYear
A drug interaction study between ticlopidine and cyclosporin in heart transplant recipients.
    European journal of clinical pharmacology, 1997, Volume: 53, Issue:1

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Double-Blind Method; Drug Interactions; Heart Transplantation; Humans; Hydrocortisone; Immunosuppressive Agents; Male; Middle Aged; Mixed Function Oxygenases; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine

1997

Other Studies

16 other study(ies) available for ticlopidine and cyclosporine

ArticleYear
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Drug points. Probable interaction between cyclosporin A and low dose ticlopidine.
    BMJ (Clinical research ed.), 2000, Apr-15, Volume: 320, Issue:7241

    Topics: Biological Availability; Cyclosporine; Drug Interactions; Female; Fibrinolytic Agents; Humans; Immunosuppressive Agents; Kidney Transplantation; Middle Aged; Oculomotor Nerve Diseases; Platelet Aggregation Inhibitors; Ticlopidine

2000
Clopidogrel-associated thrombotic thrombocytopenic purpura/hemolytic uremic syndrome in a kidney/pancreas transplant recipient.
    Transplantation, 2000, Aug-15, Volume: 70, Issue:3

    Topics: Adult; Clopidogrel; Coronary Disease; Cyclosporine; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Hemolytic-Uremic Syndrome; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Pancreas Transplantation; Plasmapheresis; Platelet Aggregation Inhibitors; Purpura, Thrombotic Thrombocytopenic; Ticlopidine

2000
Ticlopidine-induced marrow aplasia treated with cyclosporine.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2002, Volume: 8, Issue:2

    Topics: Bone Marrow Diseases; Cyclosporine; Diabetes Complications; Diabetes Mellitus; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome

2002
Treatment with ticlopidine is associated with reduction of cyclosporin a blood levels.
    Nephron, 2002, Volume: 92, Issue:1

    Topics: Cyclosporine; Drug Interactions; Female; Fibrinolytic Agents; Humans; Immunosuppressive Agents; Kidney Transplantation; Middle Aged; Ticlopidine

2002
Clopidogrel-precipitated rhabdomyolysis in a stable heart transplant patient.
    The Annals of pharmacotherapy, 2007, Volume: 41, Issue:1

    Topics: Clopidogrel; Cyclosporine; Drug Therapy, Combination; Female; Heart Transplantation; Humans; Middle Aged; Rhabdomyolysis; Simvastatin; Ticlopidine

2007
Danshen extract does not alter pharmacokinetics of docetaxel and clopidogrel, reflecting its negligible potential in P-glycoprotein- and cytochrome P4503A-mediated herb-drug interactions.
    International journal of pharmaceutics, 2011, May-30, Volume: 410, Issue:1-2

    Topics: Administration, Oral; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Clopidogrel; Cyclosporine; Cytochrome P-450 CYP3A; Docetaxel; Drugs, Chinese Herbal; Herb-Drug Interactions; Infusions, Intravenous; Male; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza; Taxoids; Ticlopidine

2011
Pharmacokinetic interactions of clopidogrel with quercetin, telmisartan, and cyclosporine A in rats and dogs.
    Archives of pharmacal research, 2012, Volume: 35, Issue:10

    Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Benzoates; Chromatography, High Pressure Liquid; Clopidogrel; Cyclosporine; Dogs; Drug Interactions; Female; Platelet Aggregation Inhibitors; Quercetin; Rats; Rats, Sprague-Dawley; Species Specificity; Telmisartan; Ticlopidine

2012