ticlopidine has been researched along with aspirin in 4265 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 68 (1.59) | 18.7374 |
| 1990's | 326 (7.64) | 18.2507 |
| 2000's | 1697 (39.79) | 29.6817 |
| 2010's | 2118 (49.66) | 24.3611 |
| 2020's | 56 (1.31) | 2.80 |
| Authors | Studies |
|---|---|
| Fukami, H; Hara, H; Kikumoto, R; Ninomiya, K; Osakabe, M; Sugano, M; Tamao, Y | 1 |
| Cillero, FJ; Fau de Casa-Juana, M; Ortega, MP; Priego, JG; Sunkel, CE | 1 |
| Campillo, N; Carrasco, E; García, C; Goya, P; Grau, M; Páez, JA | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Fang, L; Li, ZB; Liu, XH; Tian, X; Wang, LY; Xia, S; Yuan, Y; Zuo, H | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Fang, L; Liu, JQ; Tian, Y; Wang, JH; Wang, XH; Wang, Y; Xia, S; Zuo, H | 1 |
| Hua, K; Huang, Z; Ji, H; Sheng, X; Wang, X; Xu, J; Yang, C; Zhang, Y | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Choussat, A; Jimenez, M; Legrain, V; Maleville, J; Meraud, JP; Moimeaux, V; Taieb, A | 1 |
| Góra, P; Krzanowski, M; Radwan, J; Szczeklik, A | 1 |
| Dalen, JE; Fuster, V; Harker, LB; Hirsh, J; Salzman, EW | 1 |
| Andry, P; Bodemer, C; Brunelle, F; de Prost, Y; Hubert, P; Nihoul-Fékété, C; Sebag, G; Teillac-Hamel, D | 1 |
| Ando, E; Ishii, I; Matsuda, T; Nagamatsu, Y; Sasaki, Y; Yamamoto, J | 1 |
| Harbison, JW | 3 |
| Bailliart, O; Bonneau, M; Bonnin, P; Caen, JP; Drouet, LO; Maffrand, JP; Mazoyer, E; Pignaud, G; Samama, CM; Viars, P | 1 |
| Cowan, S | 1 |
| Hattori, A | 1 |
| Aosaki, M; Hosoda, S; Iwade, K; Kimata, S | 1 |
| Bregani, R; Corneo, G; Fowst, C; Pogliani, EM | 1 |
| Fogelholm, R; Kaste, M | 1 |
| Riekkinen, P; Sivenius, J | 1 |
| Easton, JD | 2 |
| Grotta, JC; Kamm, B; Norris, JW | 1 |
| Lowenthal, A | 1 |
| Inoue, M; Iwane, Y; Kobune, K; Kudo, T; Morikawa, M; Takanami, Y; Tsuboi, M | 1 |
| Karasawa, A; Kubo, K; Shirakura, S | 1 |
| Delahaye, JP; Sagnol, P | 1 |
| Hershey, LA | 1 |
| Cazenave, JP; Freund, M; Mantz, F | 1 |
| Adams, HP; Gordon, DL | 1 |
| Bernini, W; Buti Strata, G; De Caterina, R; Giannessi, D; Lazzerini, G; Sicari, R | 1 |
| Himmelreich, G; Riess, H | 1 |
| Grunfeld, S; Han, E; Joseph, R; Robertson, W | 1 |
| Katayama, Y; Kobayashi, K; Matsuyama, T; Sakata, T; Takada, T | 1 |
| Akedo, Y; Nagakawa, Y; Orimo, H; Yano, H | 1 |
| FitzGerald, GA | 2 |
| Derian, CK; Friedman, PA; Gould, RJ | 1 |
| Warlow, C | 2 |
| Balsano, F; Cimminiello, C; Violi, F | 1 |
| Nelson, E | 1 |
| Lima, JM | 1 |
| Kienast, J; Verstraete, M | 1 |
| del Zoppo, GJ | 1 |
| Cox, JL; Gotlieb, AI | 1 |
| Kobayashi, I; Kusakabe, K; Maruyama, S; Nagayama, T; Shibagaki, Y; Sone, R; Uchiyama, S | 1 |
| Arnau, JM; Carné, X; Laporte, JR | 1 |
| Johnson, M; Makuch, R | 1 |
| Goyan, JE | 2 |
| Alaimo, P; Catalano, I; Cerbone, AM; Davì, G; Notarbartolo, A; Spatola, A; Strano, A | 1 |
| Adams, HP; Anderson, S; Easton, JD; Hass, WK; Kamm, B; Molony, BA; Pryse-Phillips, W | 1 |
| Cerbone, AM; Davi, G | 1 |
| Kobayashi, I; Maruyama, S; Nagayama, T; Tsutsumi, Y; Uchiyama, S | 1 |
| Itoh, T; Kambayashi, J; Mori, T; Sakon, M; Tsujinaka, T; Uemura, Y | 1 |
| Cannizzaro, S; Davì, G; Giubilato, A; Strano, A | 1 |
| Merz, B | 1 |
| Hayashida, N | 1 |
| Hrcková, Y; Indrák, K; Jezdinský, J; Kapustová, M; Kubis, M; Scudla, V | 1 |
| Ando, Y; Ikeda, Y; Kikuchi, M; Murakami, H; Murata, M; Satoh, K; Watanabe, K | 1 |
| Bochko, II; Kuz'mina, LF; Martynov, IV; Nechaev, DD | 1 |
| Harker, LA | 2 |
| Inoue, M; Kojima, T; Morikawa, M; Tsuboi, M | 1 |
| Bertele', V; Cerletti, C; de Gaetano, G | 1 |
| Allen, BT; Anderson, CB; Freeman, MB; McGoff, MA; Sicard, GA; Valentin, LI | 1 |
| Furukawa, K; Hino, H; Kawachi, K; Konagai, N; Kudo, T; Shimizu, T | 1 |
| Liusov, VA; Savenkov, MP | 1 |
| Ambrogio, C; Coller, BS; Karpatkin, S; Pearlstein, E | 1 |
| Botindari, G; Catalano, I; Davì, G; Strano, A | 1 |
| Hachinski, VC; Mirsen, TR | 1 |
| Limet, R | 1 |
| Alberca, I; Cattaneo, M; Coccato, MP; Faioni, E; Mannucci, PM; Mari, D; Vianello, L; Vicente, V | 1 |
| Brown, BG; Chesebro, JH; Ekeström, S; Harker, LA; Henderson, AH; Jewitt, DE; Oliver, MF; Sleight, P; Verstraete, M | 1 |
| Hatsuoka, M; Kashii, A; Sasaki, K; Seiki, M | 1 |
| Murakami, M; Tohgi, H | 1 |
| Murata, T; Nishio, S; Osada, E; Tanaka, Y; Umetsu, T | 1 |
| Balbarini, A; Evangelisti, L; Gherarducci, G; Giordani, R; Mariani, M; Petronio, AS; Preti, R | 1 |
| Greenough, PG; Hershey, LA; Jaffe, DF; Yang, SL | 1 |
| David, JL | 1 |
| Edgerton, TA; Faust, KB; Geisinger, KR; Hansen, KJ; Howe, HR; Kon, ND; Meredith, JH | 1 |
| Baca, M; Boschello, M; Dalla Volta, S; Marzari, A; Pengo, V; Schivazappa, L | 1 |
| Di Perri, T | 1 |
| Díez, M; Fernández, A; Gil, M; Lasierra, J; Velázquez, E; Viladés, E | 1 |
| Hashimoto, N; Kholoussy, AM; Kumashiro, R; Matsumoto, T; Piotrowski, JJ | 1 |
| Bernat, A; Maffrand, JP; Roncucci, R; Vallée, E | 1 |
| Breddin, HK; Pauliks, V; Weichert, W | 1 |
| Offerhaus, L | 1 |
| Tullio, D | 1 |
| Kester, RC | 1 |
| Gaillard, JL; Kher, A; Lecompte, T; Samama, M | 1 |
| Hass, WK; Kamm, B | 1 |
| Tohgi, H | 1 |
| Díez, MM; Fernández, A; Gil, M; Lasierra, J; Velázquez, E; Viladés, E | 1 |
| Butler, KD; White, AM | 1 |
| Naruse, T; Ogawa, S | 1 |
| Pinon, JF | 1 |
| Hanson, SR; Harker, LA | 1 |
| Kholoussy, AM; Kumashiro, R; Matsumoto, T; Pavlides, CA | 1 |
| Paris, J | 1 |
| Blanchard, J; Blatrix, C; Panak, E; Thébault, JJ | 1 |
| Bertelé, V; de Gaetano, G | 1 |
| Verstraete, M | 1 |
| Chevolet, C; Dresse, A; Grosdent, JC; Reiters, GM | 1 |
| Conard, J; Horellou, MH; Lecrubier, C; Samama, M | 1 |
| Furukawa, Y; Kondo, M; Murakami, M; Takemura, S; Yoshikawa, T | 1 |
| Aubert, D; Ferrand, C; Loubrie, JC; Tuong, A; Tuong, CC | 1 |
| Abiko, Y; Ashida, S; Sakuma, K | 1 |
| Lindsay, R; Nunn, B | 1 |
| Imura, Y; Kiyota, Y; Nagai, Y; Nishikawa, K; Terashita, Z | 1 |
| Fitzgerald, GA; Meagher, EA | 1 |
| Oda, M; Yamashita, A; Yokota, K | 1 |
| Kariyazono, H; Moriyama, Y; Nakamura, K; Saigenji, H; Shimokawa, S; Taira, A; Toyohira, H; Yamada, K | 1 |
| Ganiats, T | 1 |
| Benveniste, E; Biron, Y; Bourdonnec, C; Faivre, R; Fajadet, J; Gaspard, P; Glatt, B; Joly, P; Morice, MC; Zemour, G | 1 |
| Bergentz, SE; Bergqvist, D; Greenfield, LJ; Lindblad, B; Nichol, BJ; Stanley, JC; Stanley, TJ; Wakefield, TW | 1 |
| Mudra, H | 1 |
| Bauters, C; Bertrand, ME; Hamon, M; Lablanche, JM; McFadden, EP; Van Belle, E | 1 |
| Ciborski, T; Rehse, K | 1 |
| Barbui, T; Camerlingo, M; Casto, L; Censori, B; Finazzi, G; Mamoli, A | 1 |
| Barbui, T; Cortelazzo, S; Finazzi, G; Galli, M; Rodeghiero, F; Ruggeri, M; Vestri, O | 1 |
| Oda, M; Yamamoto, N; Yamashita, A; Yokota, K | 1 |
| Roald, HE; Sakariassen, KS | 1 |
| Basile, AP; Fiala, TG; May, JW; Yaremchuk, MJ | 1 |
| Imura, Y; Kato, K; Kawamura, M; Nishikawa, K; Terashita, Z | 1 |
| Landau, WM | 1 |
| Barnett, HJ; Feussner, JR; Matchar, DB; McCrory, DC | 1 |
| Almagor, Y; Colombo, A; Gaglione, A; Goldberg, SL; Hall, P; Maiello, L; Martini, G; Nakamura, S; Tobis, JM | 1 |
| Kunze, K | 1 |
| Higo, K; Karasawa, A; Shirakura, S; Takeda, M | 1 |
| Mezhetskaia, IA; Shalaev, SV | 1 |
| Cazenave, JP; Panak, E; Verry, M | 1 |
| Karasawa, T; Katoh, M; Odawara, A; Sasaki, Y; Tamura, K | 1 |
| Bladin, CF; Norris, JW | 1 |
| Komiya, T; Kudo, M; Mizuno, Y; Urabe, T | 1 |
| Busse, O | 1 |
| Katayama, S; Kohriyama, T; Nakamura, S; Tanaka, E; Yamamura, Y | 1 |
| Lumley, P; Sullivan, AT; White, BP | 1 |
| Chiba, K; Sasaki, K; Suzuki, H; Takahashi, H; Tamura, K; Tohgi, H | 1 |
| Anderson, HV; Buja, LM; Ferguson, JJ; Maffrand, JP; Ober, JC; Willerson, JT; Yao, SK | 2 |
| Fukuyama, M; Handa, M; Ikeda, Y; Itagaki, I; Maruyama, S; Uchiyama, S; Yamazaki, M | 1 |
| Bernat, A; Herbert, JM | 1 |
| Kashiwaya, M; Takahashi, H; Tohgi, H; Watanabe, K | 1 |
| Bernat, A; Defreyn, G; Herbert, JM; Maffrand, JP; Mares, AM | 1 |
| Hart, RG; Rothrock, JF | 1 |
| Brey, RL | 1 |
| Aït-Chek, L; Bernat, A; Dumas, A; Herbert, JM; Savi, P | 1 |
| Hart, RG; Solomon, DH | 1 |
| Kakishita, E; Oura, Y; Suehiro, A; Ueda, M | 1 |
| Algra, A; van Gijn, J | 3 |
| Epstein, AM; Huse, DM; Lacey, MJ; Oster, G | 1 |
| Macko, R | 1 |
| Couch, JR | 1 |
| Hartmann, F | 1 |
| Durham, SK; Heran, CL; Megill, JR; Schumacher, WA; Steinbacher, TE | 1 |
| Beretz, A; Cazenave, JP; Freund, M; Gachet, C; Mantz, F; Meyer, L; Mulvihill, J; Nicolini, P | 1 |
| Greenlee, RG; Unwin, DH | 1 |
| Fujimura, M; Mikashima, H | 1 |
| Kleinsorge, H; Müller, P; Simon, B | 1 |
| Verheugt, FW | 6 |
| Bellavance, A | 1 |
| Weisberg, LA | 1 |
| Kanter, MC; Sherman, DG | 1 |
| Bruno, A | 1 |
| Grotta, J | 1 |
| Chiba, K; Takahashi, H; Tamura, K; Tohgi, H | 1 |
| Doi, H; Kaburaki, M; Murata, S; Narita, H; Yasoshima, A | 1 |
| Blengino, S; Colombo, A; Ferraro, M; Hall, P; Itoh, A; Maiello, L; Martini, G; Nakamura, S | 1 |
| Arrobas, M; Caravaca, F; Cid, MC; Cubero, J; López-Minguez, JR; Miranda, MP; Pizarro, JL; Sanchez-Casado, E | 1 |
| Belardi, J; Bonnier, H; Colombo, A; de Jaegere, P; Emanuelsson, H; Fajadet, J; Garcia, E; Goy, JJ; Heyndrickx, G; Kiemeney, F; Legrand, V; Lunn, AC; Macaya, C; Materne, P; Morel, MA; Morice, MC; Rutsch, W; Ruygrok, P; Serruys, PW; Suryapranata, H; van der Giessen, W | 1 |
| Zippel, C | 1 |
| Bihour, C; Nurden, AT; Nurden, P; Raymond, JM; Smith, M | 1 |
| Alt, E; Blasini, R; Hadamitzky, M; Kastrati, A; Neumann, FJ; Richardt, G; Schmitt, C; Schömig, A; Schühlen, H; Ulm, K; Walter, H; Zitzmann-Roth, EM | 1 |
| Fukushi, H; Imura, Y; Kawamura, M; Kita, S; Moriya, N; Nishikawa, K; Sugihara, H; Terashita, Z | 1 |
| Izawa, M; Kagawa, M; Kawamata, T; Kubo, O; Takakura, K; Takeshita, M | 1 |
| Katoh, M; Kikkawa, K; Odawara, A; Sasaki, Y; Shimazaki, T; Toryu, H | 1 |
| Iwamoto, Y; Naritomi, H; Nishimura, H; Sugita, M; Tachibana, H | 1 |
| Zuckerman, GR | 1 |
| Calpe Climent, AV; Horrach Pérez, M; Llobera C-anaves, J; Peña Díaz, JJ; Rodríguez Moreno, C; Thomàs Mulet, V; Tomàs Arbona, FJ | 1 |
| Elsman, P; Zijlstra, F | 1 |
| Bogousslavsky, J; Castillo, V; Vuadens, P | 1 |
| Díaz-Marín, C; Matías-Guiu, J | 1 |
| Aguilar, M; Bonaventura, I; Martínez, I; Quintana, S; Rey, A | 1 |
| Kuki, H; Shirasawa, Y; Takahashi, H; Tohgi, H; Watanabe, K | 1 |
| Benveniste, E; Biron, Y; Glatt, B; Guérin, Y; Lefevre, T; Lienhart, Y; Louvard, Y; Morice, MC; Valeix, B; Zemour, G | 1 |
| Eubanks, LE; Galen, W; McBurney, EI; Reed, R | 1 |
| Hosokawa, FG; Kim, K; Miyake, S; Saito, S; Tanaka, S | 1 |
| Schafer, AI | 2 |
| Gawaz, M; May, A; Neumann, FJ; Ott, I; Schömig, A | 1 |
| Bernat, A; Herbert, JM; Maffrand, JP; Samama, M | 1 |
| Bednar, MM; Booth, C; Fuller, SP; Gross, CE; Howard, D; Quilley, J; Russell, SR | 1 |
| Aubry, P; Benveniste, E; Bunouf, P; Cattan, S; Chevalier, B; Commeau, P; Cribier, A; Eiferman, C; Grollier, G; Guerin, Y; Henry, M; Karrillon, GJ; Lefevre, T; Livarek, B; Louvard, Y; Makowski, S; Marco, J; Monassier, JP; Morice, MC; Pernes, JM; Rioux, P; Spaulding, C; Zemour, G | 1 |
| Obata, Y; Oda, M; Yamamoto, N; Yokota, K | 1 |
| Bogousslavsky, J; Dewarrat, A | 1 |
| Adams, HP; Bendixen, BH | 1 |
| Kuzniar, J; Malinga, K; Mazurek, AP; Splawinska, B; Splawinski, J | 1 |
| Bauters, C; Bedossa, M; Bertrand, ME; Bonnet, JL; Danchin, N; Grollier, G; Lablanche, JM; Leclercq, C; McFadden, EP; Vahanian, A; Van Belle, E | 1 |
| Droste, DW; Kaps, M; Siemens, HJ; Sonne, M; Wagner, T | 1 |
| Droste, DW; Kaps, M; Siemens, HJ; Sonne, M | 1 |
| al-Shaibi, KF; Dean, LS; Goods, CM; Iyer, SS; Jain, SP; Liu, MW; Mathur, A; Parks, JM; Roubin, GS; Yadav, JS | 1 |
| Bertsch, G; Langenfeld, H; Markert, T; Schanzenbächer, P | 1 |
| Baron, D; Lowe, H; Roy, P | 1 |
| al-Shaibi, KF; Dean, LS; Goods, CM; Iyer, SS; Liu, MW; Mathur, A; Parks, JM; Roubin, GS; Yadav, JS | 1 |
| Nurden, AT | 1 |
| Blasini, R; Neumann, FJ; Paloncy, R; Richardt, G; Schmitt, C; Schömig, A | 1 |
| Akiyama, T; Colombo, A; Di Mario, C; Moussa, I; Reimers, B; Tobis, J | 1 |
| Bernies, M; Bossi, IM; Brunel, P; Cassagneau, B; Fajadet, J; Gregorini, L; Mannucci, PM; Marco, J | 1 |
| Colombo, A; Di Maggio, M; Gaglione, A; Hall, P; Maiello, L; Martini, G; Nakamura, S; Tiecco, F | 1 |
| Alt, E; Blasini, R; Dirschinger, J; Hadamitzky, M; Hausleiter, J; Kastrati, A; Neumann, FJ; Schmitt, C; Schömig, A; Schühlen, H; Walter, H; Zitzmann-Roth, EM | 1 |
| Stiegler, H | 1 |
| Violi, F | 1 |
| Bahadori, B; Toplak, H; Wascher, TC | 1 |
| Davie, AP; Love, MP | 1 |
| Barer, D | 1 |
| Gregorini, L; Marco, J | 1 |
| Halbmayer, WM; Haushofer, A; Prachar, H | 1 |
| Christopoulou-Cokkinou, V; Cokkinos, DV; Haliassos, A; Manolis, AS; Maounis, TN; Melita-Manolis, H; Papatheou, D; Psarros, L; Vassilikos, V | 1 |
| Catella-Lawson, F; FitzGerald, GA | 1 |
| Baim, DS; Carrozza, JP | 1 |
| Albiero, R; Blengino, S; Colombo, A; Ferraro, M; Hall, P; Itoh, A; Martini, G; Nakamura, S | 1 |
| Aurora, SK; Chant, C; Fagan, SC; Gidal, BE; Joseph, R | 1 |
| Hama, J; Ishikawa, K; Kanamasa, K; Katori, R; Kimura, A; Naito, T; Nakai, S; Ogawa, I; Oyaizu, M; Takenaka, T; Yamamoto, K; Yamamoto, T | 1 |
| Born, GV; Collins, R | 1 |
| Chaithiraphan, S; Chotinaiwattarakul, C; Kangkagate, C; Mahanonda, N | 1 |
| Barragan, P; Pietri, P; Roquebert, PO; Silvestri, M; Villain, P | 1 |
| Canaple, S; Rosa, A | 1 |
| Atkinson, R; Royal, HD; Santoro, SA; Windus, DW | 1 |
| Cho, SY; Hong, MK; Jang, YS; Kang, JC; Kim, JJ; Kim, KB; Kim, KS; Oh, BH; Oh, DJ; Park, SJ; Park, SW | 1 |
| Hadamitzky, M; Schömig, A; Schühlen, H; Ulm, K; Walter, H | 1 |
| Buller, CE; Chauhan, A; Moscovich, MD; Penn, IM; Ricci, DR; Zubaid, M | 1 |
| Cazenave, JP; Gachet, C | 1 |
| Hall, D; Neumann, FJ; Schömig, A | 1 |
| Keil, Tu | 1 |
| Blasini, R; Dickfeld, T; Gawaz, M; Neumann, FJ; Schomig, A; Walter, H; Wehinger, A | 1 |
| Hobson, AG; Sowinski, KM | 1 |
| Colombo, A; Di Francesco, L; Di Mario, C; Martini, G; Moses, J; Moussa, I; Reimers, B; Tobis, J | 1 |
| Hankey, GJ | 6 |
| Anders, RJ; Broderick, TM; Ferguson, JJ; Hantsbarger, G; Higby, NA; Kereiakes, DJ; Kleiman, N; Martin, LH; McDonald, S; Runyon, JP | 1 |
| Patrono, C; Renda, G | 1 |
| Bernat, A; Herbert, JM; Hoffmann, P; Savi, P | 1 |
| Bioulac-Sage, P; Labbé, L; Léauté-Labrèze, C; Méraud, JP; Taïeb, A | 1 |
| Aubry, P; Barragan, P; Bedossa, M; Blanchard, D; Cattan, S; Cribier, A; Elias, J; Faugier, JP; Hamon, M; Joly, P; Juliard, JM; Khalifé, K; Lefevre, T; Maillard, L; Masquet, C; Meyer, P; Monassier, JP; Morice, MC; Petiteau, PY; Raynaud, P; Rioux, P; Roriz, R; Royer, T; Spaulding, C | 1 |
| Cumberland, D; Wheeldon, N | 1 |
| Chesney, CM | 1 |
| Armstrong, PW; Brown, NE; Gill, S; Majumdar, S | 1 |
| Anzuini, A; Bonnier, H; Chierchia, SL; Coppi, R; Kulbertus, HE; Legrand, V; Marazzi, G; Montorfano, M; Pagnotta, P; Rosanio, S; Sheiban, I; Tocchi, M; Vicedomini, G | 1 |
| Colombo, A; di Mario, C; Ferraro, M; Moussa, I; Reimers, B; Reinhardt, R | 1 |
| Hacke, W; Orberk, E; Schellinger, PD | 1 |
| Lincoff, AM; Steinhubl, SR | 1 |
| Gershlick, AH | 1 |
| Azaceta, G; Civeira, E; Cornudella, R; Iturbe, T; Moreno, JA; Olave, T; Peleato, J; Sánchez, C; Varo, MJ | 1 |
| Gawaz, M; May, AE; Neumann, FJ; Ott, I; Schömig, A; Walter, H | 1 |
| Schrör, K; Weber, AA | 1 |
| Anzuini, A; Bonnier, H; Chierchia, SL; Coppi, R; Kulbertus, HE; Legrand, V; Rosanio, S; Sheiban, I; Tocchi, M | 1 |
| Stone, GW | 2 |
| Zarranz Imirizaldu, JJ | 1 |
| Eachempati, SR; Reed, RL; Sebastian, MW | 1 |
| Just, H; Nauck, M; Noory, E; van de Loo, A; Wollschläger, H | 1 |
| Choussat, R; Montalescot, G | 1 |
| Noth, J | 1 |
| Bell, MR; Berger, PB; Grill, DE; Holmes, DR; Melby, S | 1 |
| Borkowski, U; Darius, H; Genth, S; Meyer, J; Nowak, B; Rupprecht, HJ; Voigtländer, T | 1 |
| Forbes, CD | 2 |
| Stoupel, E | 1 |
| Algra, A; Koudstaal, PJ; van Gijn, J | 1 |
| Belkin, M; Conte, MS; Donaldson, MC; Whittemore, AD | 1 |
| Kariyazono, H; Moriyama, Y; Nakamura, K; Taira, A; Toyohira, H | 1 |
| Pellegrino, TR | 1 |
| Ferguson, JJ; Gonzalez, ER; Kannel, WB; Olin, JW; Raps, EC | 1 |
| Bruschke, AV; Jukema, JW; Oemrawsingh, PV; Reiber, JH; Schalij, MJ; Tuinenburg, JC | 1 |
| Lüderitz, B; Pizzulli, L | 1 |
| Diener, HC | 9 |
| Bruschke, AV; Oemrawsingh, PV; Schalij, MJ; Udayachalerm, W; van der Wall, EE | 1 |
| Alonso, M; Amaro, A; Calvo, I; Colman, T; Esplugas, E; Insa, L; Lezaun, R; López Mínguez, JR; Martínez Elbal, L; Picó, F; Vázquez, N | 1 |
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| Dambrink, JH; de Boer, MJ; Gosselink, AT; Hamm, C; Heestermans, T; Koopmans, P; Mosterd, A; ten Berg, JM; van 't Hof, AW; van Houwelingen, G; van Werkum, JW; Zijlstra, F | 1 |
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| Ahn, JM; Cho, YR; Han, S; Jang, JY; Kang, SJ; Kim, JJ; Kim, WJ; Kim, YH; Kwon, CH; Lee, CW; Lee, JY; Lee, SW; Lee, WS; Park, DW; Park, GM; Park, SJ; Park, SW; Park, YK | 1 |
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| Hariki, H; Hiranuma, N; Hirata, K; Inoue, T; Iwasaki, M; Kinutani, H; Konishi, A; Kuroda, M; Nakagawa, M; Nishio, R; Osue, T; Otake, H; Shinke, T; Taniguchi, Y | 1 |
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| Chen, C; Deng, QQ; Fu, JH; Huang, YN; Markus, H; Ratanakorn, D; Tang, J; Wong, KS; Zhao, H | 1 |
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| Armstrong, PW; Bhatt, DL; Corbalán, R; Cyr, DD; Fox, KA; Jackson, LR; Lopes, RD; Lüscher, TF; Magnus Ohman, E; Martinez, F; Neely, ML; Piccini, JP; Prabhakaran, D; Roe, MT; White, HD; Winters, KJ | 1 |
| Chaudhary, N; Gemmete, JJ; Li, P; Pandey, AS; Thompson, BG; Xi, G; Zhang, C | 1 |
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| Barbieri, L; Brouwer, MA; Camaro, C; Damen, SA; de Boer, MJ; De Luca, G; Kedhi, E; Lee, SW; Ligtenberg, E; Rognoni, A; Suryapranata, H; van T Hof, AW; Verdoia, M | 1 |
| Anstrom, KJ; Armstrong, PW; Boden, WE; Clapp-Channing, N; Cowper, P; Davidson-Ray, L; Fakhouri, W; Fox, KA; Gašparović, V; Hochman, JS; Kaul, P; Knight, JD; Mark, DB; McCollam, P; Ohman, EM; Prabhakaran, D; Roe, MT; White, HD | 1 |
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| Chao, Y; Chen, CC; Chen, TJ; Hu, YW; Huang, YH; Huo, TI; Lee, PC; Lin, HC; Liu, CJ; Su, CW; Wu, JC; Yeh, CM | 1 |
| Broderick, TM; Dalia, AA; Essandoh, MK; Flores, AS; George, BS; Kirtane, AJ; Otey, AJ; Rao, SV | 1 |
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| Ahn, JH; Gurbel, PA; Hwang, JY; Hwang, SJ; Jang, JY; Jeong, YH; Kang, MG; Kim, K; Koh, JS; Kwak, CH; Park, HW; Park, JR; Park, Y; Tantry, US | 1 |
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| He, Y; Jing, J; Li, H; Pan, Y; Wang, Y | 1 |
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| Cho, MH; Kim, EH; Kim, HK; Lee, H; Lee, SP; Lim, YK; Shin, DW; Shin, JH; Yun, JM | 1 |
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| Dong, M; Li, L; Mu, N; Ren, F; Tan, J; Zhang, C; Zhang, X | 1 |
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| Ardissino, D; Armstrong, PW; Bhatt, DL; Cornel, JH; Erlinge, D; Fox, KA; Gurbel, PA; Jakubowski, JA; Neely, B; Ohman, EM; Prabhakaran, D; Roe, MT; Tantry, US; White, HD | 1 |
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| Blankenberg, S; Brieger, D; Chen, JY; Goodman, SG; Granger, CB; Grieve, R; Maguire, A; Nicolau, JC; Pocock, SJ; Requena, G; Simon, T; Vega, AM; Yasuda, S | 1 |
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| Ben-Yehuda, O; Brodie, BR; Gupta, R; Kirtane, AJ; Mehran, R; Metzger, DC; Ozan, MO; Rinaldi, MJ; Stone, GW; Stuckey, TD; Weisz, G; Witzenbichler, B | 1 |
| Chen, W; Li, J; Lin, J; Lin, Y; Liu, L; Meng, X; Ou, L; Wang, A; Wang, D; Wang, Y; Zhao, X | 1 |
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| Becker, RC; Cannon, CP; Hagström, E; Himmelmann, A; James, SK; Katus, HA; Lindholm, D; López-Sendón, JL; Maurer, G; Siegbahn, A; Steg, PG; Storey, RF; Wallentin, L | 1 |
| Chen, W; Jing, J; Johnston, SC; Li, H; Liu, L; Meng, X; Pan, Y; Wang, D; Wang, Y; Zhao, X | 1 |
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| Barmparas, G; Bosarge, P; Brown, CV; Bukur, M; Carrick, MM; Catalano, RD; Coimbra, R; Holly-Nicolas, J; Inaba, K; Kaminski, S; Klein, AL; Kobayashi, L; Kopelman, T; Ley, EJ; Martinez, EM; Moore, FO; Murry, J; Nirula, R; Paul, D; Quick, J; Rivera, O; Schreiber, M | 1 |
| Bi, Q; Fu, P; Guo, F; Qiao, M; Song, Z; Wang, Y | 1 |
| Fiolaki, A; Giannopoulos, S; Katsanos, AH; Kosmidou, M; Kyritsis, AP; Moschonas, IC; Papadaki, S; Tselepis, AD | 1 |
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| Chen, WC; Chuah, SK; Hsu, PI; Huang, YT; Lin, KH; Sun, WC; Tsai, TJ; Wu, DC | 1 |
| Jang, HJ; Kang, WC; Kim, TH; Kwon, SW; Lee, K; Moon, J; Oh, PC; Park, HW; Park, SD; Suh, J | 1 |
| Baber, U; Vogel, B | 1 |
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| Apruzzese, PK; Cutlip, DE; Kereiakes, DJ; Massaro, JM; Mauri, L; Secemsky, EA; Steg, PG; Yeh, RW | 1 |
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| Boersma, E; Diletti, R; Fam, JM; Felix, CM; IJsselmuiden, AJJ; Lansink, WJ; Onuma, Y; Regar, ES; Smits, PC; van Geuns, RJM; Vlachojannis, GJ; Zijlstra, F | 1 |
| Armstrong, PW; Gershlick, A; Halvorsen, S; Huber, K; Shavadia, J; Steg, PG; Van de Werf, F; Welsh, R; Zheng, Y | 1 |
| Al-Qoofi, F; Chamandi, C; Côté, M; Dumont, E; Garcia Del Blanco, B; Généreux, P; Maluenda, G; Masson, JB; Paradis, JM; Pelletier, M; Rodés-Cabau, J; Serra, V; Thoenes, M; Webb, JG; Welsh, RC | 1 |
| Ahn, JM; Choi, HI; Kang, SH; Kang, SJ; Kim, YH; Lee, CW; Lee, PH; Lee, SW; Park, DW; Park, SJ; Park, SW | 1 |
| Godier, A; Houssany-Pissot, S; Martin, AC; Taylor, G; Zlotnik, D | 1 |
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| Bil, J; Bojko, K; Gil, RJ; Górny, J; Januszko-Giergielewicz, B; Kern, A; Sienkiewicz, E | 1 |
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| Bigliardi, G; Dell'Acqua, ML; Ferraro, D; Lelli, N; Mimmi, S; Nichelli, P; Pentore, R; Picchetto, L; Rosafio, F; Trenti, T; Vandelli, L; Zini, A | 1 |
| Armstrong, PW; Bhatt, DL; Cyr, DD; Dalby, AJ; Fox, KAA; Gottlieb, S; Magnus Ohman, E; McGuire, DK; Prabhakaran, D; Roe, MT; Ruzyllo, W; White, HD; Winters, KJ; Wiviott, SD | 1 |
| Aitmokhtar, O; Azaza, A; Azzouz, A; Benamara, S; Benathmane, T; Benkhedda, S; Bonello, L; Bouzid, A; Hamza, O; Harbi, F; Kara, M; Monsuez, JJ; Paganelli, F; Saidane, M; Seddiki, S; Sik, A | 1 |
| Bhatt, DL; Michelson, AD | 1 |
| Arous, S; Bentaoune, T; El Ghali Benouna, M; Habbal, R; Haboub, M | 1 |
| Ariotti, S; Baldo, A; Franzone, A; Gargiulo, G; Moschovitis, A; Piccolo, R; Santucci, A; Tumscitz, C; Valgimigli, M; Windecker, S | 1 |
| Cai, M; Chen, S; Fang, Z; Lan, B; Li, R; Ma, C; Yang, Y; Zhu, T | 1 |
| Chang, S; Chang, Y; Lu, S; Sun, Q; Zhang, Y | 1 |
| Angiolillo, DJ; Becker, RC; Cannon, CP; Himmelmann, A; Huber, K; James, SK; Katus, HA; Lowenstern, A; Morais, J; Neely, M; Siegbahn, A; Steg, PG; Storey, RF; Sun, JL; Wallentin, L | 1 |
| Chen, Q; Geng, G; Han, W; Hao, Y; Hao, Z; Jia, K; Liu, H; Liu, L; Liu, Y; Wang, D; Zhou, Y | 1 |
| Akasaka, T; Hirata, KI; Iwasaki, M; Kinutani, H; Konishi, A; Kuroda, M; Nakamura, M; Osue, T; Otake, H; Saito, S; Shinke, T; Shite, J; Takahashi, H; Takaya, T; Terashita, D; Uzu, K | 1 |
| Bertoldi Franco, J; Buhatem Medeiros, F; Gallottini, M; Itagiba Neves, IL; Ortega, KL; Pepe Medeiros de Rezende, N; Porrio de Andrade, AC; Timerman, L | 1 |
| Adlbrecht, C; Eber, B; Egger, F; Hajos, J; Helmreich, W; Huber, K; Machata, M; Michael, N; Neumayr, M; Rohla, M; Suppan, M; Tscharre, M; Weiss, TW; Zweiker, R | 1 |
| Ako, J; Ando, K; Anzai, H; Hamasaki, T; Iijima, R; Inoue, K; Ishiwata, S; Ito, Y; Kadotani, M; Kawaguchi, K; Morita, T; Nakamura, M; Niinuma, H; Nishida, Y; Ochiai, M; Ohira, H; Okada, H; Omiya, K; Shinke, T; Takiuchi, S; Tanaka, H; Ueda, Y; Yasaka, Y; Yokoi, H; Zen, K | 1 |
| Armengaud, J; Barragan, P; Ben Amer, H; Berlan, J; Blanchard, D; Bressolette, E; Carrie, D; Cassat, C; Castellant, P; Cazaux, P; Champagnac, D; Darremont, O; Dauphin, R; Delarche, N; Didier, R; Druelles, P; Dupouy, P; Furber, A; Gilard, M; Gommeaux, A; Hovasse, T; Jouve, B; Kermarrec, A; Kiss, RG; Le Breton, H; Levy, G; Lyuycx-Bore, A; Maillard, L; Majwal, T; Morice, MC; Noor, HA; Noryani, AAL; Ohlmann, P; Ormezzano, O; Paganelli, F; Sainsous, J; Schneeberger, M; Ungi, I; Wojcik, J | 1 |
| Bang, CS; Hong, KS; Hong, MK; Jeong, H; Jung, MH; Kim, CY; Park, SM | 1 |
| Bachelot-Loza, C; Belleville-Rolland, T; Gaussem, P; Godier, A; Helley, D; Martin, AC | 1 |
| Huang, RC; Yuan, C; Zhong, L | 1 |
| Jukes, A; Miljkovic, D; Psaltis, AJ; Wormald, PJ | 1 |
| Kosar, L; Koziol, K; Martens, B; Schellenberg, A; Shmyr, D | 1 |
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| Jiang, M; You, JHS | 1 |
| de Mast, Q; El Messaoudi, S; Gerretsen, J; Gomes, M; Kiers, D; Kox, M; Pickkers, P; Riksen, NP; Rongen, GA; van der Heijden, WA; van der Ven, AJ; van Ede, L | 1 |
| Budaj, A; Ramotowski, B; Żuk, A | 1 |
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| Barbieri, L; De Luca, G; Nardin, M; Suryapranata, H; Verdoia, M | 1 |
| Columbo, JA; Riblet, NBV; Stone, DH | 1 |
| Ayele, GM; Ben-Yehuda, O; Cox, DA; Duffy, PL; Furer, A; Généreux, P; Giustino, G; Henry, TD; Kirtane, AJ; Lin, SH; Maehara, A; Mazzaferri, EL; Mehran, R; Metzger, DC; Mintz, GS; Neumann, FJ; Redfors, B; Rinaldi, MJ; Stone, GW; Stuckey, TD; Weisz, G; Witzenbichler, B | 1 |
| Elisaf, M; Manios, E; Milionis, H; Ntaios, G; Papavasileiou, V; Spengos, K; Vemmos, K | 1 |
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| Fu, DL; Gao, YX; Li, XL; Liu, XF; Lu, HK; Peng, WH; Wang, Q; Wang, Y; Yang, P; Zhang, H; Zhao, TT; Zheng, JG | 1 |
| Aquino, M; Ariti, C; Baber, U; Bhasin, A; Chandrasekhar, J; Chieffo, A; Cohen, D; Colombo, A; Dangas, G; Farhan, S; Gibson, CM; Henry, TD; Iakovou, I; Kini, A; Kruckoff, M; Mehran, R; Moliterno, D; Pocock, S; Sartori, S; Schoos, M; Sorrentino, S; Steg, PG; Stuckey, T; Vogel, B; Weisz, G; Witzenbichler, B | 1 |
| Ben-Yehuda, O; Brodie, BR; Cox, DA; Duffy, PL; Généreux, P; Gurbel, PA; Henry, TD; Kirtane, AJ; Litherland, C; Mazzaferri, EL; Mehran, R; Metzger, DC; Neumann, FJ; Rinaldi, MJ; Simonton, CA; Stone, GW; Stuckey, TD; Weisz, G; Witzenbichler, B | 1 |
| Adriaenssens, T; Bernlochner, I; Byrne, RA; Colleran, R; Emmer, R; Fischer, M; Giacoppo, D; Han, Y; Harada, Y; Ibrahim, T; Jacobshagen, C; Kastrati, A; Kufner, S; Lahmann, AL; Laugwitz, KL; Lohaus, R; Maeng, M; Mayer, K; Mehilli, J; Michel, J; Morath, T; Neumann, FJ; Schulz-Schüpke, S; Schunkert, H; Seyfarth, M; Ten Berg, JM; Tölg, R; Wöhrle, J; Wolk, A; Zrenner, B | 1 |
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| Chen, XL; Dai, QL; Han, YF; Liu, WH; Liu, XF; Ma, MM; Xiong, YY; Xu, GL; Yin, Q; Zhang, RL; Zhu, WS | 1 |
| Abizaid, A; Bhatt, DL; Colombo, A; Feres, F; Gilard, M; Hong, MK; Kim, HS; Morice, MC; Palmerini, T; Piccolo, R; Stone, GW; Valgimigli, M; Windecker, S | 1 |
| Giri, J; Nathan, A | 1 |
| Han, FS; He, H; Ke, BB; Li, X; Li, Y; Zeng, YJ | 1 |
| Bhatt, DL; Cannon, CP; Ellis, SG; Gropper, S; Harper, R; Hohnloser, SH; Januzzi, JL; Kimura, T; Kleine, E; Lip, GYH; Maeng, M; Manassie, J; Merkely, B; Nordaby, M; Oldgren, J; Steg, PG; Ten Berg, JM; Zeymer, U | 1 |
| Agrifoglio, M; Benedetto, U; Bianco, M; Colombo, A; Conrotto, F; D'Amico, M; D'Ascenzo, F; D'Onofrio, A; Moretti, C; Ribichini, F; Rinaldi, M; Salizzoni, S; Tarantini, G | 1 |
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| Fu, WX; He, RX; Jing, QM; Liu, HW; Liu, YJ; Wang, XZ; Yuan, WJ; Zhang, L; Zhou, TN | 1 |
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| Brener, SJ; Dangas, GD; Deliargyris, EN; Généreux, P; Giustino, G; Kirtane, AJ; Mehran, R; Pocock, SJ; Prats, J; Redfors, B; Stone, GW | 1 |
| Agrawal, V; Almahmoud, K; Burlew, CC; Cahill, A; Campion, EM; Dissanaike, S; Foley, N; Frazee, R; Hartline, C; Jackson, T; Kim, D; Michaels, D; Nelson, P; Olatubosun, O; Pearcy, C; Regner, J; Spence, L; Stewart, C; Todd, SR; Truitt, MS | 1 |
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| Jin, J; Luo, X; Qian, C; Yang, M; Zuo, Z | 1 |
| Calabrò, P; De Luca, L; Gragnano, F | 1 |
| Alexopoulos, D; Angiolillo, DJ; Aradi, D; Bhatt, DL; Bonello, L; Cuisset, T; De Luca, L; Franchi, F; Gurbel, PA; Hochholzer, W; James, S; Mehran, R; Montalescot, G; Price, MJ; Rollini, F; Schneider, DJ; Sibbing, D; So, DYF; Storey, RF; Tantry, US; Trenk, D; Valgimigli, M; Waksman, R; Wang, TY | 1 |
| Garcellano, M; Oza, R; Rundell, K | 1 |
| Athanasiou, A; Damaskos, C; Moris, D; Politou, M; Spartalis, E; Spartalis, M; Tzatzaki, E | 1 |
| Li, YH; Wan, YM; Wu, HM; Wu, XN; Xu, Y; Xu, ZY; Yang, JH; Yang, LH | 1 |
| de Man, FHAF; Doggen, CJM; Hartmann, M; Knottnerus, IL; Kok, MM; Linssen, GCM; Louwerenburg, JW; Löwik, MM; Stoel, MG; van der Heijden, LC; van Houwelingen, KG; von Birgelen, C; Zocca, P | 1 |
| Gremmel, T; Kopp, CW; Koppensteiner, R; Lang, IM; Lee, S; Panzer, S; Pultar, J; Wadowski, PP; Weikert, C | 1 |
| Byun, JK; Choi, BG; Choi, CU; Choi, SY; Kim, EJ; Kim, JB; Na, JO; Oh, DJ; Park, CG; Rha, SW; Seo, HS | 1 |
| Jia, P; Wang, XF; Ye, M; Zeng, YJ | 1 |
| Abrams-Ogg, ACG; Blois, SL; Saati, S; Wood, RD | 1 |
| Doan, G; Kaltenbach, T; Lin, D; McQuaid, K; Mou, S; Pham, C; Rouse, RV; Shergill, AK; Soetikno, RM; Somsouk, M | 1 |
| Chorianopoulos, E; Giannitsis, E; Katus, HA; Mohr, SK; Müller, OJ; Preusch, M; Tilemann, L | 1 |
| Chen, J; Gao, LJ; Gao, RL; Gao, Z; Qiao, SB; Tang, XF; Xu, B; Xu, JJ; Yang, YJ; Yuan, JQ; Zhang, Y; Zhu, P | 1 |
| Bellesini, M; Donadini, MP; Middeldorp, S; Squizzato, A; Takeda, A | 1 |
| Chourdakis, E; Hahalis, G; Koniari, I; Kounis, NG; Patsouras, N; Roumeliotis, A; Soufras, G; Tsigkas, G | 1 |
| Appleton, JP; Bath, PM; Beridze, M; Christensen, H; Dineen, RA; Duley, L; England, TJ; Flaherty, K; Havard, D; Heptinstall, S; James, M; Krishnan, K; Markus, HS; Montgomery, AA; Pocock, SJ; Randall, M; Ranta, A; Robinson, TG; Scutt, P; Sprigg, N; Venables, GS; Woodhouse, LJ | 1 |
| Bonetti, B; Bovi, P; Cappellari, M; Forlivesi, S; Toni, D; Turcato, G; Zivelonghi, C | 1 |
| Alexander, E; Dawn, B; Gupta, K; Olyaee, M; Shaukat, A; Waheed, S; Washko, D | 1 |
| Beales, ILP | 1 |
| Consolo, F; D'Angelo, A; Della Valle, P; Pappalardo, F; Pozzi, L; Sferrazza, G; Slepian, MJ | 1 |
| Chan, PH; Kwok, OH; Lam, CC; Lam, YY; Siu, CW; Wong, CK | 1 |
| Grabovica, SG; Granov, N; Haxhibeqiri-Karabdic, I; Straus, S | 1 |
| Cai, B; Lin, A; Wu, X; Zhu, J | 1 |
| Albeiruti, AR; Malik, A; Messina, M; Pandya, U; Spalding, C | 1 |
| Adeeb, N; Alturki, AY; Griessenauer, CJ; Gupta, R; Moore, JM; Ogilvy, CS; Schneider, AM; Sieber, S; Thomas, AJ; Winkler, PA | 1 |
| Gao, BL; Li, L; Li, TX; Xu, GQ; Yang, BW | 1 |
| Grinshtein, IY; Grinshtein, YI; Kosinova, AA; Savchenko, AA; Subbotina, TN | 1 |
| Chen, WH; Lin, DL; Lin, XH; Wu, YM; Yi, TY; Zhang, MF | 1 |
| Amoroso, G; Bergmeijer, TO; Dewilde, WJ; Gimbel, ME; Godschalk, TC; Heestermans, T; Janssen, PW; Kelder, JC; Nolet, WW; Ten Berg, JM; van Kessel, DJ; Wykrzykowska, JJ | 1 |
| Chen, M; Feng, Y; Li, YJ; Liao, YB; Liu, XJ; Xiong, TY; Zhao, MY; Zhao, ZG | 1 |
| Ge, ML; Han, YL; Jing, QM; Li, L; Li, Y; Liu, HW; Ma, YY; Wang, B; Wang, G; Wang, XZ; Xu, K; Yang, BS; Zhang, L; Zhao, X | 1 |
| Chen, W; Hu, W; Kuang, X; Liu, Z; Tong, J | 1 |
| Al-Daher, S; Alwis, I; Calkin, AC; Chen, Y; Cohen, N; Cooper, ME; Coulter, B; Felner, EI; Jackson, SP; Ju, L; Maiocchi, S; McFadyen, JD; Schoenwaelder, SM; Tønnesen, LL; Yuan, Y; Zhu, C | 1 |
| Bae, JH; Cho, DK; Cho, JH; Choi, JH; Choi, KH; Choi, SH; Choi, WG; Doh, JH; Gwon, HC; Hahn, JY; Jeong, JO; Kim, BO; Kim, DI; Kim, J; Kim, SH; Lee, JB; Lee, JM; Lee, WS; Oh, JH; Park, HK; Park, JS; Park, TK; Song, YB; Suh, IW; Yang, JH | 1 |
| Bhatt, DL; Motovska, Z | 1 |
| Baorda, F; Fusco, A; Porta, L | 1 |
| Abraham, P; Henni, S; Ouedraogo, N | 1 |
| Nusdeo, G; Parodi, G; Terrosu, P | 2 |
| Kou, N; Miao, Y; Qu, H; Shi, DZ; Wang, MM; Xue, M; Yang, B; Yang, L; Zang, MX | 1 |
| Pitts-Tucker, T; Small, J | 1 |
| Liu, X; Zhang, JJ | 1 |
| Chan, KA; Lai, CL; Lai, HY; Lai, MS; Lin, TT; Yang, YY | 1 |
| Adnan, S; Ali, S; Ali, T; Farooq, M; Gill, SA; Masood, Z; Saleem, H; Shabbir, M; Shahid, N; Waqar, K | 1 |
| Hanna Deschamps, E; Hanna, EB | 1 |
| Cohn, SL; Munyon, R; Pfeifer, K; Slawski, B; Smetana, GW | 1 |
| Agarwal, SK; Garg, N; Goel, P; Kapoor, A; Khanna, R; Kumar, S; Pande, S; Pereira, P; Sinha, A; Srivastava, N; Tewari, S | 1 |
| Bath, PM; Heptinstall, S; May, J | 1 |
| Lader, E | 1 |
| Davda, N; Osman, C | 1 |
| Barsan, W; Conwit, RA; Easton, JD; Elm, JJ; Farrant, M; Johnston, SC; Kim, AS; Lindblad, AS; Palesch, YY | 1 |
| Crowther, MA; Eikelboom, JW | 1 |
| Bulaeva, NI; Golukhova, EZ; Grigoryan, MV; Ryabinina, MN | 2 |
| Belcaro, G; Cesarone, MR; Cornelli, U; Corsi, M; Cotellese, R; Dugall, M; Errichi, BM; Feragalli, B; Hosoi, M; Hu, S; Ippolito, E; Ledda, A; Ricci, A | 1 |
| Chai, Z; Han, Z; Huang, R; Lin, J; Wang, C; Yi, X; Zhou, Q | 1 |
| Ding, L; Peng, B | 1 |
| Cho, KH; Choi, KH; Kim, JT; Lee, JS; Park, MS; Saver, JL | 1 |
| Krajcer, Z; Shatila, W | 1 |
| Cui, M; Gu, ZC; Li, WY; Pan, MM; Yao, JC | 1 |
| Brunner, S; Hamm, W; Lackermair, K; Mehr, M; Rizas, K | 1 |
| Velázquez de Campos, O | 1 |
| Alderson, P; Lewis, SR; Pritchard, MW; Schofield-Robinson, OJ; Smith, AF | 1 |
| Berry, C; Dawson, J; Mazlan-Kepli, W; Walters, M | 1 |
| Hoorntje, JCA | 1 |
| Bellesini, M; Donadini, MP; Squizzato, A | 1 |
| Choi, SY; Kim, MH | 1 |
| Espinola-Klein, C | 1 |
| Chen, W; Fu, Y; Li, W; Liu, Z; Tang, Y; Wang, W; Wang, Z; Zhang, X; Zhou, Z | 1 |
| Belcaro, G; Cotellese, R; Dugall, M; Eggenhoffner, R; Giacomelli, L; Hosoi, M; Hu, S; Ledda, A; Peterzan, P; Riva, A; Togni, S | 1 |
| Jiang, WJ; Li, C; Liu, AF; Qiu, H; Wang, K; Wu, Z; Zhang, Y; Zhou, J | 1 |
| Chai, Z; Lin, J; Wang, C; Yi, X; Zhou, Q | 1 |
| Benit, E; Chichareon, P; Dominici, M; Ferrario, M; Hamm, C; Heg, D; Huber, K; Janssens, L; Jüni, P; McFadden, EP; Möllmann, H; Moschovitis, A; Onuma, Y; Serruys, PW; Slagboom, T; Steg, PG; Valgimigli, M; van Es, GA; Van Geuns, RJ; van Meijeren, C; Vranckx, P; Windecker, S; Zurakowski, A | 1 |
| Kim, B; Kim, HR; Kweon, OJ; Lee, MK; Lim, YK | 1 |
| Li, J; Yan, G | 1 |
| De Rosa, R; Palmerini, T; Piscione, F | 1 |
| Frelinger, AL; Gachet, C; Gresele, P; Harrison, P; Mezzano, D; Mumford, AD; Noris, P | 1 |
| Hoppe, UC; Jung, C; Lauten, A; Lichtenauer, M; Navarese, EP; Wernly, B | 1 |
| Huang, B; Wang, J; Xiang, Y; Zhao, J | 1 |
| Geng, XY; Ma, JG; Wei, YY; Yu, HR | 1 |
| Armon, C; Rapoport, M; Sherban, A | 1 |
| Fujii, T; Hayashi, T; Hirata, KI; Igarashi, N; Ishihara, T; Kadotani, M; Kawamori, H; Matsumoto, D; Matsuura, A; Nagano, Y; Nagasawa, A; Okada, M; Onishi, H; Otake, H; Sakakibara, T; Shinke, T; Shite, J; Sugizaki, Y; Takeshige, R; Toba, T; Tsukiyama, Y; Yamamoto, H; Yanaka, K; Yasaka, Y | 1 |
| Karkouti, K; Wijeysundera, DN | 1 |
| Easton, JD; Kim, AS | 1 |
| Li, XY; Lyu, QZ; Shen, JQ; Song, K; Wang, Z; Xia, LM | 1 |
| Byrne, RA; Colleran, R; Kastrati, A | 1 |
| Belcaro, G; Bradford, HD; Cesarone, MR; Cotellese, R; Dugall, M; Feragalli, B; Gizzi, C; Hosoi, M; Hu, S; Rodriguez, P | 1 |
| Ashby, D; Lyon, C | 1 |
| Chen, PC; Chen, ZW; Huang, JW; Lee, JK; Lin, LY; Lin, YH; Wu, CK; Wu, VC; Yang, YH | 1 |
| Abe, S; Inoue, T; Kanaya, T; Koyabu, Y; Nakajima, T; Obi, S; Sakuma, M; Toyoda, S; Yoneda, S | 1 |
| Dinh, AT; Luu, NM; Nguyen, TTH; Nguyen, VH | 1 |
| Moliterno, DJ; Ziada, KM | 1 |
| Fotydar, S; Katyal, VK; Verma, PSFVK | 1 |
| Chen, C; Huang, S; Lin, D; Luo, Y; Wu, Y; Yu, W | 1 |
| Doshi, R; Kumar, A; Shariff, M | 1 |
| De Luca, G; Fierro, N; Gioscia, R; Nardin, M; Negro, F; Pergolini, P; Rolla, R; Saghir Afifeh, AM; Suryapranata, H; Verdoia, M; Viglione, F | 1 |
| Cannata, F; Cao, D; Chiarito, M; Condorelli, G; De Caterina, R; Ferrante, G; Godino, C; Panico, C; Regazzoli, D; Reimers, B; Sanz-Sánchez, J; Stefanini, GG; Sturla, M | 1 |
| Di, Y; Guo, T; Hou, J; Kong, F; Li, Y; Ming, JE; Ping, C; Wang, L; Xie, F; Yang, N; Yin, H; Zhang, L | 1 |
| Ahn, CM; Cho, DK; Cho, JY; Cho, S; Cho, YH; Choi, D; Her, AY; Hong, BK; Hong, MK; Hong, SJ; Jang, Y; Jeon, DW; Kim, BK; Kim, JS; Kim, YH; Ko, YG; Kwon, H; Nam, CM; Shin, DH; Suh, Y; Yoo, SY; Yun, KH | 1 |
| Robson, A | 1 |
| Galiuto, L; Patrono, C | 2 |
| Hoang, C; Levitt, MR; Mak, HY; Sandler, M | 1 |
| Eichelberger, B; Gremmel, T; Panzer, S; Pultar, J; Tscharre, M; Wadowski, PP; Weikert, C | 1 |
| Hsu, YH; Ong, CT; Tsai, CF; Wong, YS | 1 |
| Chen, F; Chen, SL; Gao, DS; Gao, XF; Ge, Z; Han, YL; He, YQ; Kan, J; Kong, XQ; Li, F; Lin, S; Liu, ZZ; Qian, XS; Qu, H; Shao, YB; Tao, L; Tian, NL; Wang, Y; Wang, ZZ; Wen, SY; Xia, Y; Xiao, PX; Yang, Q; Yang, S; Ye, F; Zeng, HS; Zhang, JJ; Zuo, GF | 1 |
| Paliy, IG; Vernyhorodskyi, SV; Yankovetska, AG; Zaika, SV | 1 |
| Dong, Z; Pan, L; Zhai, H; Zhang, B | 1 |
| Harada, K; Kohara, H; Matsumiya, K; Shinozawa, T; Yukawa, T | 1 |
| Carretero Rodrigo, M; Lipperheide Vallhonrat, I; Ortega Marcos, J; Parra Esteban, C; Silva Melchor, L; Vela Martín, P | 1 |
| Dou, KF; Wang, HY | 1 |
| Algra, A; Bath, PM; Csiba, L; Diener, HC; Greving, JP; Hacke, W; Hilkens, NA; Kappelle, LJ; Koudstaal, PJ; Leys, D; Mas, JL; Sacco, RL | 1 |
| Altınay, L; Çetin, E | 1 |
| Lyu, SQ; Shao, XH; Wang, J; Wu, S; Yang, YM; Zhang, H; Zhu, J | 1 |
| Du, Y; He, L; Liu, Q; Wang, H; Wang, J; Xu, J; Xu, X | 1 |
| Azzopardi, LM; Barbara, C; Camilleri, L; Osama, S; Wirth, F; Xuereb, RG; Zahra, G | 1 |
| Hvas, AM; Nissen, PH; Pedersen, TF; Schultz-Lebahn, A; Tang, M | 1 |
| Fang, S; Li, F; Li, H; Li, T; Qin, S; Zhang, S; Zhu, B; Zhu, J | 1 |
| Martínez-Quintana, E; Medina-Gil, JM; Rodríguez-González, F; Saavedra-Santana, P; Santana-Mateos, M; Tugores, A | 1 |
| Doran, T; Keles, EC; Kirac, D; Mihmanli, M; Yaman, AE | 1 |
| Barry, HC | 1 |
| Friebel, J; Hassanein, A; Jakobs, K; Landmesser, U; Puccini, M; Rauch, C; Rauch, U | 1 |
| Ahn, CM; Cho, JY; Choi, D; Hong, MK; Hong, SJ; Jang, Y; Kim, BK; Kim, JS; Ko, YG; Lee, SJ; Lee, YJ; Yun, KH | 1 |
| de Havenon, A; Kraler, L; Lansberg, MG; Zhou, LW | 1 |
| Demchuk, AM; Jahn, B; Menon, BK; Micieli, A; Siebert, U; Singh, N | 1 |
| Cheng, J; Deng, X; Li, H; Ma, Y; Shi, T; Wang, X; Wu, Y; Zhang, Z; Zhu, Q | 1 |
| Fujii, S; Fujita, K; Hirai, S; Ishikawa, M; Karakama, J; Miki, K; Nemoto, S; Sumita, K; Yamaoka, H; Yoshimura, M | 1 |
| Fan, X; Jiao, L; Ma, H; Meng, X; Wang, J; Zhao, L | 1 |
| Patrono, C | 1 |
| Dookeeram, D; Giddings, S; Gomes, C; Grimaldos, G; Grimaldos, K; Ishmael, A; Kampradi, L; Peram, L; Ramlackhansingh, A; Raza, S; Richard, S; Sandy, S; Schneider, D; Seecheran, NA; Seecheran, R; Seecheran, V; Sukha, D; Tello-Montoliu, A; Umaharan, P | 1 |
| Patrono, C; Vergallo, R | 1 |
| Moustafa, B; Testai, FD | 1 |
| Chang, R; Liu, Y; Wu, J; Ye, Y; Zhang, X; Zhou, W | 1 |
| Cheng, Y; Li, D; Liu, H; Shao, T; Wang, H; Yang, T; Zhang, J; Zhang, T | 1 |
| Ahlbrecht, S; Dannenberg, L; Helten, C; Hohlfeld, T; Huhn, R; Kelm, M; M'Pembele, R; Mourikis, P; Naguib, D; Petzold, T; Polzin, A; Trojovsky, K; Zako, S; Zeus, T | 1 |
| Li, X; Lv, Q; Wang, Z; Xu, S; Yao, Y | 1 |
| Falcinelli, E; Gresele, P; Guglielmini, G; Isernia, G; Lenti, M; Mezzasoma, AM; Simonte, G | 1 |
| Aldica, M; Anchidin, OI; Blendea, D; Moldovan, H; Molnar, A; Nemes, A; Pop, D; Rosianu, SH | 1 |
| Atar, D; Gurvich, ML; Marciniak, TA; Serebruany, VL; Tanguay, JF | 1 |
| Chen, S; Li, M; Li, Y; Pan, H; Qiang, J; Tian, R; Yuan, T; Zhang, Y; Zhao, B; Zhu, H | 1 |
| Manunga, J; Pai, A; Pedersen, C; Skeik, N; Stanberry, L; Sullivan, TM | 1 |
| Bellomo, T; Boada, AE; Dua, A; Goudot, G; Hall, RP; Jessula, S; Kukreja, N; Lee, I; Majumdar, M; Parmar, G; Suarez Ferreira, SP | 1 |
| Huang, J; Liao, F; Shu, X; Tang, J | 1 |
| Dahlen, JR; Hosokawa, K; Kitagawa, K; Ohnishi, T; Shirai, Y; Yamazaki, M | 1 |
| Ahmad, FS; Anderson, RD; Benziger, CP; Effron, MB; Farrehi, P; Girotra, S; Gupta, K; Harrington, RA; Hernandez, AF; Jain, SK; Jones, WS; Kripalani, S; Marquis-Gravel, G; Muñoz, D; Polonsky, TS; Roe, MT; Rothman, RL; Stebbins, A; Whittle, J; Wruck, L | 1 |
| Algarni, RA; Alshargi, O; Alshehri, S; Alshibani, M; Althagafi, AA | 1 |
| Kristensen, SD; Maeng, M; Thim, T | 1 |
872 review(s) available for ticlopidine and aspirin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Aspirin and other platelet-active drugs. The relationship between dose, effectiveness, and side effects.
Topics: Anticoagulants; Aspirin; Cerebrovascular Disorders; Dipyridamole; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Humans; Myocardial Infarction; Thrombosis; Ticlopidine | 1992 |
[The use of drugs that affect thrombocytes in cerebral ischemia].
Topics: Aspirin; Blood Platelets; Brain Ischemia; Dipyridamole; Female; Humans; Male; Ticlopidine | 1990 |
Antiplatelet therapy in the prevention of stroke.
Topics: Aspirin; Cerebrovascular Disorders; Dipyridamole; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Sulfinpyrazone; Ticlopidine | 1991 |
[Anticoagulant or antiplatelet aggregation treatment after aortocoronary bypass].
Topics: Anticoagulants; Aspirin; Coronary Artery Bypass; Dipyridamole; Graft Occlusion, Vascular; Humans; Meta-Analysis as Topic; Platelet Aggregation Inhibitors; Sulfinpyrazone; Ticlopidine; Vitamin K | 1991 |
Stroke prevention in women: role of aspirin versus ticlopidine.
Topics: Aspirin; Cerebrovascular Disorders; Female; Humans; Meta-Analysis as Topic; Recurrence; Sex Factors; Ticlopidine; United States | 1991 |
Epidemiology of and stroke-preventive strategies for atherothromboembolic brain infarction in the elderly.
Topics: Aged; Anticoagulants; Arteriosclerosis; Aspirin; Cerebral Infarction; Cerebrovascular Disorders; Female; Humans; Intracranial Embolism and Thrombosis; Ischemic Attack, Transient; Male; Middle Aged; Pentoxifylline; Risk Factors; Ticlopidine | 1991 |
Ticlopidine, a new antithrombotic drug: but is it better than aspirin for longterm use?
Topics: Aspirin; Cerebrovascular Disorders; Humans; Ischemic Attack, Transient; Myocardial Infarction; Randomized Controlled Trials as Topic; Ticlopidine | 1990 |
Current use of antiplatelet drugs in stroke syndromes in the USA.
Topics: Aspirin; Cerebrovascular Disorders; Female; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine | 1990 |
Pharmacology of the interaction between platelets and vessel wall.
Topics: Animals; Aspirin; Blood Platelets; Blood Vessels; Dextrans; Diltiazem; Dipyridamole; Epoprostenol; Humans; Imidazoles; Ketanserin; Piperidines; Pyrazoles; Pyrazolones; Sulfinpyrazone; Sulfonamides; Thiophenes; Ticlopidine | 1986 |
Antiplatelet therapy in thrombotic thrombocytopenic purpura.
Topics: Aspirin; Blood Platelets; Dextrans; Dipyridamole; Epoprostenol; Humans; Microcirculation; Platelet Aggregation; Purpura, Thrombotic Thrombocytopenic; Sulfinpyrazone; Ticlopidine | 1987 |
Review of antiplatelet drug use in preventing restenosis following percutaneous transluminal coronary angioplasty.
Topics: Angioplasty, Balloon; Aspirin; Calcium Channel Blockers; Coronary Disease; Cyclooxygenase Inhibitors; Dextrans; Humans; Nitrates; Phosphodiesterase Inhibitors; Phospholipases; Platelet Aggregation Inhibitors; Propranolol; Recurrence; Thromboxane-A Synthase; Ticlopidine | 1988 |
Issues in planning and interpreting active control equivalence studies.
Topics: Adult; Aspirin; Cerebrovascular Disorders; Clinical Trials as Topic; Humans; Random Allocation; Research Design; Sulfinpyrazone; Ticlopidine | 1989 |
[Platelet function inhibitors in peripheral arteriopathies].
Topics: Adrenal Cortex Hormones; Adrenergic alpha-Antagonists; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Arteriosclerosis Obliterans; Aspirin; Blood Platelets; Calcium Channel Blockers; Clinical Trials as Topic; Cyclic AMP; Dipyridamole; Extremities; Heparin; Humans; Imidazoles; Prostaglandins; Prostanoic Acids; Pyrazoles; Pyrazolones; Quinacrine; Thiophenes; Thromboembolism; Thrombosis; Ticlopidine; Vascular Diseases | 1986 |
[Thrombosis in various diseases: myocardial infarct].
Topics: Angioplasty, Balloon; Aspirin; Dipyridamole; Humans; Myocardial Infarction; Platelet Aggregation; Thiophenes; Thrombosis; Ticlopidine | 1986 |
Antiplatelet drugs in the management of patients with thrombotic disorders.
Topics: Arterial Occlusive Diseases; Arteriosclerosis; Aspirin; Blood Coagulation Disorders; Blood Platelets; Catheterization; Cerebrovascular Disorders; Coronary Disease; Dipyridamole; Glomerulonephritis; Humans; Sulfinpyrazone; Suloctidil; Thiophenes; Thrombophlebitis; Thrombosis; Ticlopidine; Vascular Diseases; Vascular Surgical Procedures | 1986 |
[Antiplatelet drugs and prevention of aortocoronary bypass occlusion].
Topics: Aspirin; Coronary Artery Bypass; Dipyridamole; Humans; Platelet Aggregation Inhibitors; Sulfinpyrazone; Thrombosis; Ticlopidine | 1988 |
Transient ischemic attacks and stroke.
Topics: Aspirin; Cerebrovascular Disorders; Humans; Ischemic Attack, Transient; Risk Factors; Ticlopidine | 1988 |
Clinical trials evaluating platelet-modifying drugs in patients with atherosclerotic cardiovascular disease and thrombosis.
Topics: Anticoagulants; Aspirin; Blood Platelets; Blood Vessel Prosthesis; Cardiovascular Diseases; Clinical Trials as Topic; Dipyridamole; Double-Blind Method; Female; Glomerulonephritis; Graft Occlusion, Vascular; Heart Valve Prosthesis; Humans; Ischemic Attack, Transient; Male; Myocardial Infarction; Postoperative Complications; Random Allocation; Sulfinpyrazone; Thiophenes; Ticlopidine | 1986 |
[Role of antiaggregant platelet drugs in thromboembolism].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anti-Bacterial Agents; Aspirin; Cerebrovascular Disorders; Dextrans; Dipyridamole; Humans; Mitral Valve; Platelet Aggregation; Platelet Function Tests; Pyridines; Pyridinolcarbamate; Random Allocation; Sulfinpyrazone; Suloctidil; Thiophenes; Thromboembolism; Ticlopidine | 1981 |
[Pharmacology of anti-platelet agents].
Topics: Animals; Anticoagulants; Aspirin; Blood Platelets; Cyclic AMP; Cyclooxygenase Inhibitors; Dipyridamole; Epoprostenol; Female; Fibrinolytic Agents; Humans; In Vitro Techniques; Intestinal Absorption; Kinetics; Male; Papio; Platelet Aggregation; Prostaglandin Antagonists; Rabbits; Sulfinpyrazone; Thiophenes; Thrombosis; Thromboxane A2; Ticlopidine | 1983 |
Antiplatelet drugs.
Topics: Animals; Arterial Occlusive Diseases; Aspirin; Dipyridamole; Humans; Integrins; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine | 1994 |
Medical treatment for stroke prevention.
Topics: Aspirin; Atrial Fibrillation; Cerebrovascular Disorders; Humans; Ischemic Attack, Transient; Myocardial Infarction; Recurrence; Risk Factors; Ticlopidine; Warfarin | 1994 |
Antiplatelet therapy in the prevention of ischaemic stroke.
Topics: Aspirin; Brain Ischemia; Clinical Trials as Topic; Dose-Response Relationship, Drug; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 1994 |
Antithrombotic therapies for stroke prevention.
Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Brain Ischemia; Cerebrovascular Disorders; Fibrinolytic Agents; Humans; Ticlopidine | 1994 |
Antiplatelet therapy in the treatment of cerebrovascular disease.
Topics: Adult; Aged; Aspirin; Cardiovascular Diseases; Cerebrovascular Disorders; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Ticlopidine | 1993 |
Prophylactic drug therapy in cerebrovascular disease.
Topics: Aspirin; Cerebrovascular Disorders; Humans; Ticlopidine; Warfarin | 1993 |
[Blood platelet aggregation inhibitors in the treatment of heart diseases].
Topics: Angina, Unstable; Aspirin; Coronary Artery Disease; Coronary Disease; Dipyridamole; Humans; Platelet Aggregation Inhibitors; Primary Prevention; Ticlopidine | 1993 |
Strategies for preventing stroke.
Topics: Adult; Aged; Aspirin; Blood Pressure; Cerebrovascular Disorders; Endarterectomy, Carotid; Female; Humans; Male; Middle Aged; Myocardial Infarction; Risk Factors; Ticlopidine | 1993 |
[Current status of primary and secondary prevention of cerebral apoplexy].
Topics: Aspirin; Cerebrovascular Disorders; Humans; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine | 1995 |
An ounce of prevention. Toward preventing gastrointestinal endoscopic complications.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibiotic Prophylaxis; Anticoagulants; Aspirin; Diagnostic Tests, Routine; Dipyridamole; Endocarditis, Bacterial; Endoscopy, Gastrointestinal; Humans; Hypoglycemic Agents; Insulin; Medical History Taking; Physical Examination; Platelet Aggregation Inhibitors; Ticlopidine; Vasodilator Agents; Warfarin | 1996 |
[Preventive treatment of cerebrovascular accidents of arterial origin].
Topics: Adult; Aged; Anticoagulants; Arterial Occlusive Diseases; Arteriosclerosis; Aspirin; Clinical Trials as Topic; Humans; Intracranial Embolism and Thrombosis; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine | 1996 |
Linear scleroderma in children.
Topics: Administration, Topical; Adolescent; Anti-Infective Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Betamethasone; Child; Dermatologic Agents; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Male; Methylprednisolone; Penicillins; Phenytoin; Scleroderma, Localized; Ticlopidine; Vitamin E | 1996 |
Antiplatelet therapy.
Topics: Aspirin; Dipyridamole; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine | 1996 |
[Antithrombotic agents and prevention of cerebrovascular accidents].
Topics: Aspirin; Atrial Fibrillation; Cerebrovascular Disorders; Clopidogrel; Echocardiography; Humans; Intracranial Embolism and Thrombosis; Platelet Aggregation Inhibitors; Primary Prevention; Ticlopidine | 1996 |
Ticlopidine or clopidogrel as alternatives to aspirin in prevention of ischemic stroke.
Topics: Aspirin; Brain Ischemia; Cerebrovascular Disorders; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 1996 |
New thoughts on strategies for modulating platelet function through the inhibition of surface receptors.
Topics: Animals; Aspirin; Blood Platelets; Clopidogrel; Drug Evaluation, Preclinical; Endothelium, Vascular; Humans; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Cell Surface; Signal Transduction; Thrombosis; Ticlopidine; Type C Phospholipases | 1996 |
Confusion in reperfusion. Problems in the clinical development of antithrombotic drugs.
Topics: Abciximab; Antibodies, Monoclonal; Aspirin; Cerebrovascular Disorders; Drug Therapy, Combination; Fibrinolytic Agents; Heparin; Humans; Immunoglobulin Fab Fragments; Ischemic Attack, Transient; Myocardial Infarction; Myocardial Ischemia; Platelet Aggregation Inhibitors; Ticlopidine; Tissue Plasminogen Activator | 1997 |
Stent thrombosis. Closing in on the best preventive treatment.
Topics: Aspirin; Atherectomy; Coronary Disease; Humans; Platelet Aggregation Inhibitors; Recurrence; Stents; Thrombosis; Ticlopidine | 1997 |
[Antiplatelet therapy during coronary endoprosthesis placement].
Topics: Angioplasty, Balloon, Coronary; Aspirin; Coronary Disease; Coronary Thrombosis; Drug Therapy, Combination; Drug Tolerance; Echocardiography; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Recurrence; Stents; Ticlopidine | 1996 |
Anti-platelet drugs: do they affect megakaryocytes?
Topics: Aspirin; Blood Platelets; Cyclic AMP; Humans; Megakaryocytes; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine | 1997 |
Ticlopidine and aspirin therapy following implantation of coronary artery stents.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clinical Trials as Topic; Coronary Disease; Coronary Thrombosis; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 1997 |
Antiplatelet therapy with glycoprotein IIb/IIIa receptor inhibitors and other novel agents.
Topics: Aspirin; Dipyridamole; Hemorrhage; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombosis; Ticlopidine | 1997 |
Platelet activation and inhibition in unstable coronary syndromes.
Topics: Angina, Unstable; Aspirin; Humans; Myocardial Infarction; Platelet Activation; Platelet Aggregation Inhibitors; Thromboxane A2; Ticlopidine | 1997 |
Tufted angioma associated with platelet trapping syndrome: response to aspirin.
Topics: Aspirin; Biopsy; Blood Platelet Disorders; Child, Preschool; Combined Modality Therapy; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Hemangioma, Capillary; Humans; Platelet Aggregation Inhibitors; Skin Neoplasms; Syndrome; Ticlopidine | 1997 |
Pharmacologic prevention of acute ischemic complications of coronary angioplasty.
Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Constriction, Pathologic; Coronary Disease; Fibrinolytic Agents; Heparin; Humans; Immunoglobulin Fab Fragments; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine | 1997 |
[Antithrombotic therapy after cerebral ischemia].
Topics: Aspirin; Brain Ischemia; Clopidogrel; Dipyridamole; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fibrinolytic Agents; Heparin; Heparinoids; Humans; Intracranial Embolism and Thrombosis; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine; Treatment Outcome | 1997 |
[Pharmacology of ticlopidine and clopidogrel in comparison with acetylsalicylic acid].
Topics: Aspirin; Cerebrovascular Disorders; Clopidogrel; Coronary Thrombosis; Death, Sudden, Cardiac; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 1997 |
[Anti-aggregation therapy for prevention of cerebral ischemic stroke: a risk benefit analysis].
Topics: Aspirin; Brain Ischemia; Clinical Trials as Topic; Humans; Platelet Aggregation Inhibitors; Risk; Ticlopidine | 1997 |
Posttraumatic bilateral carotid artery and right vertebral artery dissections in a patient with fibromuscular dysplasia: case report and review of the literature.
Topics: Accidents, Traffic; Adult; Aortic Dissection; Aspirin; Carotid Artery Diseases; Female; Fibromuscular Dysplasia; Humans; Multiple Trauma; Platelet Aggregation Inhibitors; Ticlopidine; Vertebral Artery; Wounds, Nonpenetrating | 1998 |
[Secondary prevention following cerebral ischemia: is monotherapy with acetylsalicylic acid still first choice?].
Topics: Anticoagulants; Aspirin; Brain Ischemia; Cerebral Hemorrhage; Cerebrovascular Disorders; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Recurrence; Ticlopidine | 1998 |
Anticoagulants and antiplatelet agents in acute ischemic stroke.
Topics: Acute Disease; Anticoagulants; Aspirin; Brain Ischemia; Cerebrovascular Disorders; Clinical Trials as Topic; Humans; Platelet Aggregation Inhibitors; Prognosis; Ticlopidine; Warfarin | 1998 |
Beyond aspirin.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Thrombosis; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine | 1998 |
Antiplatelet drugs in secondary prevention of stroke.
Topics: Aged; Aspirin; Cerebrovascular Disorders; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Ticlopidine | 1998 |
Choosing the most appropriate treatment for stable angina. Safety considerations.
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Calcium Channel Blockers; Drug Interactions; Estrogen Replacement Therapy; Female; Humans; Hypolipidemic Agents; Myocardial Infarction; Nitrates; Prognosis; Smoking Cessation; Ticlopidine | 1998 |
[Antithrombotic agents in unstable angina. Review of clinical trials].
Topics: Angina, Unstable; Aspirin; Clopidogrel; Fibrinolytic Agents; Heparin, Low-Molecular-Weight; Hirudin Therapy; Humans; Platelet Aggregation Inhibitors; Thrombolytic Therapy; Ticlopidine | 1998 |
The results of CAPRIE, IST and CAST. Clopidogrel vs. Aspirin in Patients at Risk of Ischaemic Events. International Stroke Trial. Chinese Acute Stroke Trial.
Topics: Aspirin; Cerebrovascular Disorders; Clopidogrel; Double-Blind Method; Humans; Ischemia; Myocardial Infarction; Platelet Aggregation Inhibitors; Recurrence; Ticlopidine | 1998 |
Atherosclerosis: a unifying disorder with diverse manifestations.
Topics: Arteriosclerosis; Aspirin; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Ticlopidine; United States | 1998 |
Antiplatelet therapy in coronary artery disease: review and update of efficacy studies.
Topics: Abciximab; Antibodies, Monoclonal; Aspirin; Clopidogrel; Coronary Disease; Dipyridamole; Humans; Immunoglobulin Fab Fragments; Platelet Aggregation Inhibitors; Ticlopidine | 1998 |
Clinical considerations in selecting antiplatelet therapy in cerebrovascular disease.
Topics: Aspirin; Cerebrovascular Disorders; Clopidogrel; Dipyridamole; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 1998 |
Management of peripheral arterial disease.
Topics: Arterial Occlusive Diseases; Aspirin; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 1998 |
Evolution of improved antithrombotic and antiplatelet agents: genesis of the Comparison of Abciximab Complications with Hirulog [and back-Up Abciximab] Events Trial (CACHET).
Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Antithrombins; Aspirin; Cardiac Catheterization; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Heparin; Hirudin Therapy; Hirudins; Humans; Immunoglobulin Fab Fragments; Myocardial Infarction; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Recombinant Proteins; Research Design; Ticlopidine | 1998 |
Platelet-active drugs: the relationships among dose, effectiveness, and side effects.
Topics: Aspirin; Cyclooxygenase Inhibitors; Dipyridamole; Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine | 1998 |
Antithrombotic therapy in peripheral arterial occlusive disease.
Topics: Angioplasty, Balloon, Coronary; Arterial Occlusive Diseases; Aspirin; Clopidogrel; Endarterectomy, Carotid; Fibrinolytic Agents; Graft Occlusion, Vascular; Humans; Leg; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Thromboembolism; Ticlopidine; Warfarin | 1998 |
[Drug-induced platelet functional disorder].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Blood Platelet Disorders; Heparin; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 1998 |
Clinical pharmacology of the adenosine diphosphate (ADP) receptor antagonist, clopidogrel.
Topics: Adenosine Diphosphate; Animals; Arteriosclerosis; Aspirin; Clopidogrel; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Rats; Receptors, Purinergic P2; Signal Transduction; Thrombosis; Ticlopidine | 1998 |
Results of the CAPRIE trial: efficacy and safety of clopidogrel. Clopidogrel versus aspirin in patients at risk of ischaemic events.
Topics: Arteriosclerosis; Aspirin; Cerebrovascular Disorders; Clopidogrel; Follow-Up Studies; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk Assessment; Ticlopidine; Treatment Outcome | 1998 |
Antiplatelet therapy. Aspirin, ticlopidine/clopidogrel, and anti-integrin agents.
Topics: Aspirin; Clopidogrel; Humans; Integrins; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine | 1998 |
Antiplatelet agents and stroke prevention.
Topics: Aspirin; Atrial Fibrillation; Cerebrovascular Disorders; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Female; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine | 1998 |
Antiplatelet drugs in secondary prevention after acute myocardial infarction.
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine | 1998 |
Stroke: part I. A clinical update on prevention.
Topics: Aspirin; Atrial Fibrillation; Carotid Stenosis; Cerebrovascular Disorders; Clinical Trials as Topic; Endarterectomy, Carotid; Humans; Patient Education as Topic; Platelet Aggregation Inhibitors; Risk; Risk Factors; Teaching Materials; Ticlopidine | 1999 |
Antiplatelet drugs.
Topics: Abciximab; Antibodies, Monoclonal; Aspirin; Cardiovascular Diseases; Dipyridamole; Humans; Immunoglobulin Fab Fragments; Platelet Aggregation Inhibitors; Ticlopidine | 1999 |
Antiplatelet therapy for secondary stroke prevention.
Topics: Aspirin; Cerebrovascular Disorders; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Risk Factors; Survival Rate; Ticlopidine | 1999 |
Clopidogrel with aspirin is the optimal antiplatelet regimen for intracoronary stenting.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Disease; Coronary Thrombosis; Drug Therapy, Combination; Hematologic Diseases; Humans; Platelet Aggregation Inhibitors; Premedication; Randomized Controlled Trials as Topic; Stents; Ticlopidine | 1999 |
Low molecular weight heparins in the cardiac catheterization laboratory.
Topics: Abciximab; Angina, Unstable; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Aspirin; Cardiac Catheterization; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Enoxaparin; Fibrinolytic Agents; Heparin; Heparin, Low-Molecular-Weight; Humans; Immunoglobulin Fab Fragments; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine; Tunica Intima | 1999 |
Aspirin and ticlopidine after routine coronary stenting: the gold standard as of 1999.
Topics: Anemia, Aplastic; Angioplasty, Balloon, Coronary; Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Disease; Coronary Thrombosis; Drug Therapy, Combination; Health Policy; Hematologic Diseases; Hemorrhage; Humans; Multivariate Analysis; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Premedication; Purpura, Thrombotic Thrombocytopenic; Randomized Controlled Trials as Topic; Retrospective Studies; Risk; Stents; Ticlopidine; Treatment Outcome | 1999 |
Antiplatelet therapy for treatment of acute coronary syndromes.
Topics: Abciximab; Acetates; Antibodies, Monoclonal; Aspirin; Clopidogrel; Coronary Disease; Eptifibatide; Humans; Immunoglobulin Fab Fragments; Peptides; Platelet Aggregation Inhibitors; Ticlopidine; Tirofiban; Treatment Outcome; Tyrosine; Vascular Patency | 1999 |
Management of high-risk subsets in unstable angina.
Topics: Angina, Unstable; Angioplasty, Balloon, Coronary; Aspirin; Atherectomy, Coronary; Calcium Channel Blockers; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Heparin; Heparin, Low-Molecular-Weight; Hirudin Therapy; Humans; Intra-Aortic Balloon Pumping; Nitrates; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Stents; Ticlopidine | 1999 |
[Current therapy for unstable angina pectoris].
Topics: Angina, Unstable; Anti-Bacterial Agents; Anticholesteremic Agents; Anticoagulants; Antithrombins; Aspirin; Clopidogrel; Cyclooxygenase Inhibitors; Fibrinolytic Agents; Heparin; Hirudin Therapy; Humans; Macrolides; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine | 1999 |
Therapeutic benefit. Aspirin revisited in light of the introduction of clopidogrel.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Decision Making; Humans; Platelet Aggregation Inhibitors; Secondary Prevention; Ticlopidine; Treatment Outcome | 1999 |
Adjuvant medical therapy in peripheral bypass surgery.
Topics: Alprostadil; Anticoagulants; Aspirin; Chemotherapy, Adjuvant; Clinical Trials as Topic; Dextrans; Double-Blind Method; Femoral Artery; Heparin, Low-Molecular-Weight; Humans; Iloprost; Ischemia; Leg; Platelet Aggregation Inhibitors; Popliteal Artery; Prospective Studies; Randomized Controlled Trials as Topic; Ticlopidine; Vascular Surgical Procedures | 1999 |
Bleeding complications in secondary stroke prevention by antiplatelet therapy: a benefit-risk analysis.
Topics: Aspirin; Cerebrovascular Disorders; Clopidogrel; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Recurrence; Risk; Ticlopidine; Treatment Outcome | 1999 |
Antiplatelet therapy in the prevention of ischemic vascular events: literature review and evidence-based guidelines for drug selection.
Topics: Algorithms; Arteriosclerosis; Aspirin; Brain Ischemia; Clinical Trials as Topic; Clopidogrel; Critical Pathways; Evidence-Based Medicine; Humans; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Risk; Ticlopidine | 1999 |
Antiplatelet agents in the prevention of cardiovascular morbidity and mortality in older patients with vascular disease.
Topics: Aged; Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Female; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine; Vascular Diseases | 1999 |
Ticlopidine and clopidogrel.
Topics: Adenosine Diphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Angina, Unstable; Aspirin; Bone Marrow Diseases; Carbamazepine; Cardiovascular Diseases; Clopidogrel; Combined Modality Therapy; Coronary Disease; Drug Interactions; Hemorrhage; Humans; Myocardial Infarction; Peripheral Vascular Diseases; Phenytoin; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Receptors, Purinergic P2; Safety; Stents; Theophylline; Thrombolytic Therapy; Ticlopidine | 1999 |
Platelet-endothelial interactions in atherothrombotic disease: therapeutic implications.
Topics: Animals; Arteriosclerosis; Aspirin; Disease Progression; Endothelium, Vascular; Humans; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Risk Factors; Thrombosis; Ticlopidine | 1999 |
[Antiplatelet therapy].
Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Arteriosclerosis; Aspirin; Clinical Trials as Topic; Clopidogrel; Collagen; Humans; Immunoglobulin Fab Fragments; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Thromboembolism; Thrombophilia; Ticlopidine | 1999 |
Antiplatelet therapy in interventional cardiology: I. Newer oral antiplatelet agents.
Topics: Administration, Oral; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Disease; Drug Administration Schedule; Humans; Platelet Aggregation Inhibitors; Postoperative Complications; Randomized Controlled Trials as Topic; Stents; Thrombosis; Ticlopidine | 2000 |
Ticlopidine-induced aplastic anemia and quick recovery with G-CSF: case report and literature review.
Topics: Aged; Aged, 80 and over; Anemia, Aplastic; Aspirin; Bone Marrow Cells; Coronary Disease; Female; Gastrointestinal Hemorrhage; Granulocyte Colony-Stimulating Factor; Humans; Kidney Failure, Chronic; Leukocyte Count; Platelet Aggregation Inhibitors; Platelet Count; Ticlopidine | 2000 |
Antiplatelet and anticoagulant therapy in the secondary prevention of ischemic heart disease.
Topics: Anticoagulants; Aspirin; Clopidogrel; Coronary Disease; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Recurrence; Ticlopidine; Treatment Outcome | 2000 |
Clopidogrel and [symbol: see text] ticlopidine--improvements on aspirin?
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Contraindications; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stents; Ticlopidine | 1999 |
Aspirin, ticlopidine and clopidogrel in and out of the catheterization laboratory.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 1999 |
[Aspirin and cerebral ischemic accidents].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Cerebral Infarction; Clinical Trials as Topic; Clopidogrel; Cyclooxygenase Inhibitors; Dipyridamole; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Phosphodiesterase Inhibitors; Placebos; Platelet Aggregation Inhibitors; Primary Prevention; Recurrence; Risk Factors; Stroke; Ticlopidine; Vasodilator Agents; Warfarin | 2000 |
Thienopyridine derivatives (ticlopidine, clopidogrel) versus aspirin for preventing stroke and other serious vascular events in high vascular risk patients.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2000 |
Thienopyridines or aspirin to prevent stroke and other serious vascular events in patients at high risk of vascular disease? A systematic review of the evidence from randomized trials.
Topics: Aspirin; Brain Ischemia; Clopidogrel; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Ticlopidine | 2000 |
Vascular drugs in the new millennium.
Topics: Abciximab; Animals; Anistreplase; Antibodies, Monoclonal; Anticoagulants; Aspirin; Chondroitin Sulfates; Clopidogrel; Dermatan Sulfate; Drug Combinations; Fibrinolytic Agents; Heparin, Low-Molecular-Weight; Heparitin Sulfate; Humans; Immunoglobulin Fab Fragments; Intermittent Claudication; Platelet Aggregation Inhibitors; Streptokinase; Ticlopidine; Vascular Diseases; Venous Thrombosis | 2000 |
Antiplatelet agents in cardiology: the choice of therapy.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Disease; Coronary Thrombosis; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Stents; Ticlopidine | 2000 |
The thienopyridines in coronary artery disease.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Disease; Coronary Thrombosis; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stents; Ticlopidine | 1999 |
[Platelet antiaggregants].
Topics: Aspirin; Cardiovascular Diseases; Cyclooxygenase Inhibitors; Dipyridamole; Drug Utilization; Fibrinolytic Agents; Humans; Phosphodiesterase Inhibitors; Platelet Aggregation Inhibitors; Risk Factors; Spain; Ticlopidine | 2000 |
Optimization of platelet therapy.
Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Atherectomy, Coronary; Clopidogrel; Coronary Disease; Humans; Immunoglobulin Fab Fragments; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Randomized Controlled Trials as Topic; Stents; Ticlopidine; Treatment Outcome | 2000 |
Antiplatelet agents for stroke prevention.
Topics: Aspirin; Clopidogrel; Dipyridamole; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Stroke; Ticlopidine | 2000 |
Prevention of ischaemic stroke--antiplatelets.
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Secondary Prevention; Stroke; Ticlopidine | 2000 |
Update on clinical trials of antiplatelet therapy for cerebrovascular diseases.
Topics: Aspirin; Cerebrovascular Disorders; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine | 2000 |
Antiplatelet agents in stroke prevention. combination therapy: present and future.
Topics: Abciximab; Antibodies, Monoclonal; Aspirin; Clopidogrel; Dipyridamole; Humans; Immunoglobulin Fab Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Purinergic P2 Receptor Antagonists; Stroke; Ticlopidine | 2000 |
[Therapeutic inhibition of platelets in a acute coronary syndrome and in coronary intervention: mechanisms and clinical results].
Topics: Abciximab; Acute Disease; Adult; Angina Pectoris; Angina, Unstable; Angioplasty, Balloon, Coronary; Animals; Antibodies, Monoclonal; Aspirin; Blood Platelets; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Coronary Disease; Cyclooxygenase Inhibitors; Humans; Immunoglobulin Fab Fragments; Meta-Analysis as Topic; Mice; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Randomized Controlled Trials as Topic; Receptors, Purinergic P2; Stents; Syndrome; Ticlopidine | 2000 |
Antiplatelet medications and their indications in preventing and treating coronary thrombosis.
Topics: Aspirin; Clopidogrel; Coronary Thrombosis; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine | 2000 |
Antithrombotic therapy in cardiac stent patients.
Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clopidogrel; Coronary Disease; Humans; Immunoglobulin Fab Fragments; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Stents; Ticlopidine | 2001 |
Novel platelet inhibitors.
Topics: Arteriosclerosis; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Humans; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine; Treatment Outcome | 2001 |
Stroke prevention: antiplatelet and antithrombolytic therapy.
Topics: Anticoagulants; Aspirin; Brain Damage, Chronic; Carotid Stenosis; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Endarterectomy, Carotid; Fibrinolytic Agents; Gastritis; Goals; Hemorrhage; Heparin, Low-Molecular-Weight; Humans; Ischemic Attack, Transient; Meta-Analysis as Topic; Multicenter Studies as Topic; Neutropenia; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Recurrence; Risk; Safety; Single-Blind Method; Stroke; Thrombolytic Therapy; Ticlopidine; Treatment Failure; Treatment Outcome | 2000 |
Antiplatelet therapy in the elderly. Aspirin, ticlopidine-clopidogrel, and GPIIb/GPIIIa antagonists.
Topics: Aged; Aged, 80 and over; Aspirin; Clinical Trials as Topic; Clopidogrel; Female; Humans; Male; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prognosis; Sensitivity and Specificity; Thromboembolism; Ticlopidine; Treatment Outcome | 2001 |
Stent thrombosis in the modern era: a pooled analysis of multicenter coronary stent clinical trials.
Topics: Aspirin; Blood Vessel Prosthesis Implantation; Causality; Coronary Disease; Coronary Thrombosis; Endpoint Determination; Female; Graft Occlusion, Vascular; Humans; Incidence; Logistic Models; Male; Middle Aged; Multicenter Studies as Topic; Myocardial Revascularization; Odds Ratio; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Survival Rate; Ticlopidine; Treatment Outcome | 2001 |
Benefit of ADP receptor antagonists in atherothrombotic patients: new evidence.
Topics: Arteriosclerosis; Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Purinergic P2 Receptor Antagonists; Randomized Controlled Trials as Topic; Thrombosis; Ticlopidine | 2001 |
Regular or "super-aspirins"? A review of thienopyridines or aspirin to prevent stroke.
Topics: Aspirin; Clopidogrel; Drug Combinations; Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stroke; Ticlopidine | 2001 |
[Acute coronary syndromes: an update. I. Pathogenesis and drug therapy].
Topics: Acute Disease; Administration, Oral; Adrenergic beta-Antagonists; Angina, Unstable; Anticoagulants; Aspirin; Calcium Channel Blockers; Clinical Trials as Topic; Clopidogrel; Electrocardiography; Fibrinolytic Agents; Humans; Multicenter Studies as Topic; Myocardial Infarction; Nitrates; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Risk Factors; Syndrome; Terminology as Topic; Ticlopidine; Tirofiban; Tyrosine | 2001 |
Aspirin in patients with coronary artery disease: is it simply irresistible?
Topics: Abciximab; Antibodies, Monoclonal; Aspirin; Benzamidines; Clinical Trials as Topic; Clopidogrel; Coronary Disease; Cyclooxygenase Inhibitors; Diabetes Complications; Dipyridamole; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Endothelium, Vascular; Fibrinolytic Agents; Humans; Immunoglobulin Fab Fragments; Oximes; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prospective Studies; Randomized Controlled Trials as Topic; Stroke; Thrombosis; Thromboxane-A Synthase; Ticlopidine; Vasodilator Agents | 2001 |
The use of antiplatelet agents in acute cardiac care.
Topics: Aspirin; Clopidogrel; Coronary Disease; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine | 2001 |
Complications of oral antiplatelet medications.
Topics: Administration, Oral; Aspirin; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine | 2001 |
Antiplatelet agents for secondary prevention of ischemic stroke.
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Cost-Benefit Analysis; Dipyridamole; Humans; Myocardial Ischemia; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2001 |
What can I do to continue walking despite intermittent claudication?
Topics: Aspirin; Cilostazol; Clopidogrel; Humans; Intermittent Claudication; Tetrazoles; Ticlopidine; Vasodilator Agents; Walking | 2001 |
Platelet glycoprotein IIb/IIIa blockers for percutaneous coronary revascularization, and unstable angina and non-ST-segment elevation myocardial infarction.
Topics: Angina, Unstable; Angioplasty, Balloon, Coronary; Aspirin; Fibrinolytic Agents; Heparin; Humans; Myocardial Infarction; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine | 2001 |
Ticlopidine versus oral anticoagulation for coronary stenting.
Topics: Administration, Oral; Anticoagulants; Aspirin; Coronary Thrombosis; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stents; Ticlopidine | 2001 |
New approaches to the pharmacological treatment of angina.
Topics: Angina Pectoris; Angina, Unstable; Angioplasty, Balloon, Coronary; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Calcium Channel Blockers; Clinical Trials as Topic; Drug Therapy, Combination; Fibrinolytic Agents; Heparin; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombin; Thrombolytic Therapy; Ticlopidine | 2001 |
Combination therapy with clopidogrel and aspirin: can the CURE results be extrapolated to cerebrovascula patients?
Topics: Angina, Unstable; Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Humans; Middle Aged; Platelet Aggregation Inhibitors; Secondary Prevention; Stroke; Ticlopidine; Treatment Outcome | 2001 |
Meta-analysis of randomized and registry comparisons of ticlopidine with clopidogrel after stenting.
Topics: Aspirin; Clopidogrel; Coronary Disease; Coronary Thrombosis; Drug Therapy, Combination; Humans; Odds Ratio; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Registries; Stents; Ticlopidine | 2002 |
New antiplatelet agents: ticlopidine and clopidogrel. Antiplatelet therapy but at what cost?
Topics: Aspirin; Bone Marrow; Clopidogrel; Humans; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine | 2001 |
Rationale for the use of platelet aggregation inhibitors in PAD patients.
Topics: Aspirin; Clopidogrel; Humans; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine; Treatment Outcome | 2001 |
[Antithrombotic treatment protocols in interventional cardiology].
Topics: Aspirin; Clopidogrel; Drug Resistance; Enoxaparin; Fibrinolytic Agents; Heparin; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk Factors; Stents; Thrombosis; Ticlopidine | 2001 |
From CURE to MATCH: ADP receptor antagonists as the treatment of choice for high-risk atherothrombotic patients.
Topics: Angina, Unstable; Aspirin; Clopidogrel; Drug Therapy, Combination; Heparin; Humans; Intracranial Arteriosclerosis; Intracranial Thrombosis; Ischemic Attack, Transient; Myocardial Infarction; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Recurrence; Risk Factors; Stroke; Ticlopidine | 2002 |
Persistence of the prothrombotic state after acute coronary syndromes: implications for treatment.
Topics: Angina, Unstable; Aspirin; Clopidogrel; Coronary Thrombosis; Heparin, Low-Molecular-Weight; Humans; Myocardial Infarction; Platelet Glycoprotein GPIIb-IIIa Complex; Randomized Controlled Trials as Topic; Thrombolytic Therapy; Ticlopidine; Time Factors; Warfarin | 2002 |
The use of antithrombotic drugs in older people.
Topics: Aged; Aspirin; Clopidogrel; Fibrinolytic Agents; Heparin; Heparin, Low-Molecular-Weight; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Pulmonary Embolism; Secondary Prevention; Stroke; Thromboembolism; Thrombolytic Therapy; Ticlopidine; Venous Thrombosis; Warfarin | 2002 |
[Acute gastrointestinal bleeding in patients with antithrombotic therapy].
Topics: Acute Disease; Anticoagulants; Aspirin; Coumarins; Deamino Arginine Vasopressin; Gastrointestinal Hemorrhage; Heart Valve Prosthesis; Hemostatics; Heparin; Humans; Thrombolytic Therapy; Ticlopidine | 2002 |
Preventing atherothrombotic events in peripheral arterial disease: the use of antiplatelet therapy.
Topics: Algorithms; Arteriosclerosis; Aspirin; Clopidogrel; Humans; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine | 2002 |
The role of platelets in peripheral arterial disease: therapeutic implications.
Topics: Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; Peripheral Vascular Diseases; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine | 2002 |
[Modern therapy in acute coronary syndrome].
Topics: Angina, Unstable; Anticoagulants; Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Survival Rate; Ticlopidine | 2002 |
[Prevention of recurrence in cerebral infarction].
Topics: Anticoagulants; Arteriosclerosis; Aspirin; Atrial Fibrillation; Cerebral Infarction; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Meta-Analysis as Topic; Platelet Aggregation Inhibitors; Secondary Prevention; Ticlopidine; Warfarin | 2002 |
Antithrombotic drugs for prevention of recurrent stroke.
Topics: Adult; Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Female; Fibrinolytic Agents; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Secondary Prevention; Stroke; Ticlopidine; Treatment Outcome | 2002 |
Antiplatelet treatment in unstable angina: aspirin, clopidogrel, glycoprotein IIb/IIIa antagonist, or all three?
Topics: Administration, Oral; Angina, Unstable; Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Costs; Drug Therapy, Combination; Humans; Infusions, Intravenous; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine | 2002 |
Antithrombotic agents: implications in dentistry.
Topics: Anticoagulants; Aspirin; Blood Coagulation Tests; Clopidogrel; Dental Care; Drug Interactions; Embolism; Fibrinolytic Agents; Hemostasis; Heparin; Heparin, Low-Molecular-Weight; Humans; Oral Hemorrhage; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombosis; Ticlopidine; Tirofiban; Tyrosine; Venous Thrombosis; Warfarin | 2002 |
Aspirin beyond platelet inhibition.
Topics: Abciximab; Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Aspirin; Clopidogrel; Coronary Artery Disease; Humans; Immunoglobulin Fab Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine | 2002 |
Role of antiplatelet agents in cardioprotection.
Topics: Arteriosclerosis; Aspirin; Cardiotonic Agents; Cardiovascular Diseases; Clopidogrel; Female; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine; United States | 2002 |
Clopidogrel in interventional cardiology: questions answered and questions remaining.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Randomized Controlled Trials as Topic; Stents; Ticlopidine | 2002 |
Unstable angina.
Topics: Angina, Unstable; Aspirin; Drug Therapy, Combination; Fibrinolytic Agents; Heparin, Low-Molecular-Weight; Hirudin Therapy; Hirudins; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Randomized Controlled Trials as Topic; Ticlopidine; Treatment Outcome | 2002 |
State of the art--a journey through the world of antithrombotic therapy.
Topics: Ambulatory Care; Arterial Occlusive Diseases; Aspirin; Clopidogrel; Coronary Disease; Fibrinolytic Agents; Heart Failure; Hemorrhage; Heparin, Low-Molecular-Weight; Humans; Orthopedic Procedures; Platelet Aggregation Inhibitors; Postoperative Complications; Practice Guidelines as Topic; Recurrence; Respiratory Insufficiency; Thromboembolism; Thrombolytic Therapy; Thrombophlebitis; Thrombosis; Ticlopidine | 2002 |
A benefit-risk assessment of agents used in the secondary prevention of stroke.
Topics: Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Antihypertensive Agents; Aspirin; Clinical Trials as Topic; Clopidogrel; Coumarins; Dipyridamole; Humans; Hypertension; Hypoglycemic Agents; Insulin; Platelet Aggregation Inhibitors; Risk Assessment; Risk Factors; Smoking Cessation; Stroke; Ticlopidine; Warfarin | 2002 |
Contemporary antithrombotic strategies in patients undergoing coronary stent implantation.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Coronary Disease; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Registries; Risk Factors; Stents; Thrombosis; Ticlopidine; Time Factors | 2002 |
Combination antiplatelet therapy: implications for pharmacists.
Topics: Adult; Aspirin; Clopidogrel; Coronary Restenosis; Drug Therapy, Combination; Eptifibatide; Female; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Patient Compliance; Peptides; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Stents; Ticlopidine | 2002 |
Spontaneous multivessel coronary artery dissection in a long-distance runner successfully treated with oral antiplatelet therapy.
Topics: Adult; Aortic Dissection; Aspirin; Clopidogrel; Coronary Aneurysm; Exercise; Female; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Radiography; Ticlopidine | 2002 |
[Secondary and primary prevention of coronary heart disease: platelet aggregation inhibitors and anticoagulants].
Topics: Anticoagulants; Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Interactions; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Recurrence; Risk Factors; Ticlopidine | 2002 |
Management of patients with intermittent claudication.
Topics: Aspirin; Blood Vessel Prosthesis; Cilostazol; Clopidogrel; Exercise Therapy; Humans; Intermittent Claudication; Medical History Taking; Pentoxifylline; Physical Examination; Platelet Aggregation Inhibitors; Tetrazoles; Ticlopidine; Vasodilator Agents | 2002 |
Clinical implications of CURE and PCI-CURE in patients with the acute coronary syndrome without persistent ST-elevation.
Topics: Acute Disease; Anticoagulants; Aspirin; Clopidogrel; Coronary Disease; Electrocardiography; Heparin, Low-Molecular-Weight; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Syndrome; Ticlopidine | 2002 |
Platelets: is aspirin sufficient or must we know how to pronounce abciximab?
Topics: Abciximab; Antibodies, Monoclonal; Arteriosclerosis; Aspirin; Blood Platelets; Clopidogrel; Endarterectomy, Carotid; Humans; Immunoglobulin Fab Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyridines; Ticlopidine; Tirofiban; Tyrosine | 2002 |
Utility of platelet adp receptor antagonism in the emergency department: a review.
Topics: Aspirin; California; Clopidogrel; Coronary Disease; Critical Care; Drug Utilization; Emergency Service, Hospital; Female; Humans; Male; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prognosis; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Risk Assessment; Severity of Illness Index; Stroke; Survival Analysis; Ticlopidine; Treatment Outcome | 2003 |
[Endovascular brachytherapy to prevent restenosis after angioplasty].
Topics: Angioplasty, Balloon; Angioplasty, Balloon, Coronary; Arterial Occlusive Diseases; Aspirin; Brachytherapy; Clinical Trials as Topic; Clopidogrel; Combined Modality Therapy; Coronary Restenosis; Follow-Up Studies; Humans; Retreatment; Stents; Ticlopidine | 2003 |
Unstable angina.
Topics: Angina, Unstable; Aspirin; Drug Therapy, Combination; Fibrinolytic Agents; Heparin, Low-Molecular-Weight; Hirudin Therapy; Hirudins; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine | 2002 |
Sirolimus-eluting stents: a review of experimental and clinical findings.
Topics: Angina Pectoris; Angioplasty, Balloon, Coronary; Animals; Aspirin; Clopidogrel; Coronary Angiography; Coronary Disease; Coronary Restenosis; Disease Models, Animal; Drug Delivery Systems; Follow-Up Studies; Humans; Immunosuppressive Agents; Injections, Intramuscular; Multicenter Studies as Topic; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Rats; Sirolimus; Stents; Swine; Thrombosis; Ticlopidine; Time Factors; Ultrasonography, Interventional | 2002 |
Short- and long-term oral antiplatelet therapy in acute coronary syndromes and percutaneous coronary intervention.
Topics: Acute Disease; Administration, Oral; Angina, Unstable; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Thrombosis; Drug Therapy, Combination; Humans; Myocardial Infarction; Outcome Assessment, Health Care; Platelet Activation; Platelet Aggregation Inhibitors; Ticlopidine | 2003 |
Platelet activation in patients with congestive heart failure: do we have enough evidence to consider clopidogrel?
Topics: Angiotensin-Converting Enzyme Inhibitors; Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Heart Failure; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Ticlopidine; Treatment Outcome | 2003 |
Preventing stroke in patients with atrial fibrillation: current treatments and new concepts.
Topics: Aspirin; Atrial Appendage; Atrial Fibrillation; Azetidines; Benzylamines; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Prodrugs; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Ticlopidine; Treatment Outcome; Warfarin | 2003 |
Appropriate antiplatelet and antithrombotic therapy in patients with acute coronary syndromes: recent updates to the ACC/AHA guidelines.
Topics: Abciximab; Angina, Unstable; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clopidogrel; Fibrinolytic Agents; Heparin; Humans; Immunoglobulin Fab Fragments; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Practice Guidelines as Topic; Survival Rate; Ticlopidine | 2002 |
Evidence with antiplatelet therapy and ADP-receptor antagonists.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Stroke; Thrombosis; Ticlopidine | 2003 |
[Platelet inhibitors: old and new].
Topics: Abciximab; Antibodies, Monoclonal; Arteriosclerosis; Aspirin; Clopidogrel; Coronary Disease; Dipyridamole; Drug Monitoring; Eptifibatide; Humans; Immunoglobulin Fab Fragments; Membrane Proteins; Patient Selection; Peptides; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thrombosis; Thromboxanes; Ticlopidine | 2002 |
Aspirin and clopidogrel in patients with ACS undergoing PCI: CURE and PCI-CURE.
Topics: Adult; Aged; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Emergency Service, Hospital; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Assessment; Severity of Illness Index; Survival Analysis; Ticlopidine; Treatment Outcome | 2003 |
[Anti thrombotic therapy after coronary thrombolysis].
Topics: Anticoagulants; Aspirin; Coronary Restenosis; Drug Therapy, Combination; Fibrinolytic Agents; Heparin; Heparin, Low-Molecular-Weight; Humans; Myocardial Infarction; Myocardial Reperfusion; Platelet Aggregation Inhibitors; Thrombolytic Therapy; Ticlopidine; Tissue Plasminogen Activator; Warfarin | 2003 |
[Anticoagulant, antiplatelet agents].
Topics: Anticoagulants; Aspirin; Death, Sudden, Cardiac; Dipyridamole; Drug Therapy, Combination; Heparin; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Ticlopidine; Warfarin | 2003 |
Aspirin and clopidogrel in acute coronary syndromes: therapeutic insights from the CURE study.
Topics: Acute Disease; Aspirin; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Syndrome; Ticlopidine | 2003 |
[Clopidogrel: background information and use in clinical practice].
Topics: Arteriosclerosis; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Stroke; Thrombosis; Ticlopidine | 2003 |
What is the role for improved long-term antiplatelet therapy after percutaneous coronary intervention?
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Brachytherapy; Clopidogrel; Coronary Disease; Cyclooxygenase Inhibitors; Drug Therapy, Combination; Endothelium, Vascular; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Stents; Thrombosis; Ticlopidine; Warfarin | 2003 |
[Update cardiology 2001/2002-part II. From unstable coronary syndrome to terminal heart failure].
Topics: Abciximab; Acute Disease; Adrenergic beta-Antagonists; Angina, Unstable; Antibodies, Monoclonal; Anticholesteremic Agents; Arrhythmias, Cardiac; Aspirin; Atorvastatin; Clopidogrel; Defibrillators, Implantable; Double-Blind Method; Fibrinolytic Agents; Heart Failure; Heart Septal Defects, Atrial; Heart Transplantation; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoglobulin Fab Fragments; Myocardial Infarction; Placebos; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrroles; Quality of Life; Randomized Controlled Trials as Topic; Regeneration; Risk Factors; Syndrome; Ticlopidine; Time Factors; Tirofiban; Tyrosine | 2003 |
The role of platelets and platelet inhibition in acute myocardial infarction.
Topics: Animals; Aspirin; Blood Platelets; Clopidogrel; Fibrinolytic Agents; Humans; Membrane Glycoproteins; Myocardial Infarction; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Ticlopidine; Tissue Plasminogen Activator | 2003 |
Contemporary use of antiplatelet therapies in percutaneous coronary interventions.
Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clopidogrel; Coronary Disease; Hirudins; Humans; Immunoglobulin Fab Fragments; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Recombinant Proteins; Stents; Ticlopidine | 2003 |
Clinical pharmacokinetics of antiplatelet agents used in the secondary prevention of stroke.
Topics: Aspirin; Aspirin, Dipyridamole Drug Combination; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Drug Combinations; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2003 |
[Stent thrombosis in patients with myocardial infarction].
Topics: Angioplasty, Balloon, Coronary; Aspirin; Coronary Angiography; Coronary Thrombosis; Fibrinolytic Agents; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Risk Factors; Stents; Ticlopidine; Time Factors; Ultrasonography, Interventional | 2003 |
Combined antiplatelet therapy in atrial fibrillation: review of the literature and future avenues.
Topics: Aspirin; Atrial Fibrillation; Clopidogrel; Drug Combinations; Evidence-Based Medicine; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stroke; Thrombosis; Ticlopidine; Treatment Outcome | 2003 |
Review of antithrombotic agents used for acute coronary syndromes in renal patients.
Topics: Acute Disease; Anticoagulants; Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Disease; Fibrinolytic Agents; Hemorrhagic Disorders; Humans; Kidney Diseases; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombolytic Therapy; Ticlopidine | 2003 |
Angina (unstable).
Topics: Angina, Unstable; Aspirin; Clopidogrel; Heparin, Low-Molecular-Weight; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine; Warfarin | 2003 |
Antiplatelet treatment in stable coronary artery disease.
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Disease; Drug Interactions; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Purinergic P2 Receptor Antagonists; Ticlopidine | 2003 |
[Antiplatelet drugs in prevention and treatment of coronary heart disease: aspirin is obligatory, quite sufficient, and safe].
Topics: Angiotensin-Converting Enzyme Inhibitors; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Interactions; Drug Resistance; Drug Tolerance; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine | 2003 |
[Antiplatelet drugs in prevention of complications of arteriosclerotic diseases: it is necessary to move beyond aspirin].
Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Death, Sudden, Cardiac; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2003 |
The role of clopidogrel in the management of acute coronary syndromes.
Topics: Acute Disease; Angina, Unstable; Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Disease; Cost-Benefit Analysis; Drug Interactions; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2003 |
Treatment of unstable angina pectoris/non-ST-segment elevation myocardial infarction in elderly patients.
Topics: Adrenergic beta-Antagonists; Aged; Angina, Unstable; Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Aspirin; Clopidogrel; Coronary Angiography; Drug Therapy, Combination; Electrocardiography; Humans; Hypolipidemic Agents; Myocardial Infarction; Oxygen Inhalation Therapy; Ticlopidine | 2003 |
[Treatment of acute stroke -- an overview].
Topics: Abciximab; Antibodies, Monoclonal; Anticoagulants; Aspirin; Brain Edema; Case-Control Studies; Cerebral Infarction; Clinical Trials, Phase IV as Topic; Clopidogrel; Contraindications; Double-Blind Method; Fibrinolytic Agents; Heparin; Humans; Hypertension; Immunoglobulin Fab Fragments; Intracranial Pressure; Intubation, Intratracheal; Ischemic Attack, Transient; Meta-Analysis as Topic; Middle Aged; Multicenter Studies as Topic; Placebos; Plasminogen Activators; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prospective Studies; Randomized Controlled Trials as Topic; Respiration, Artificial; Stroke; Thrombolytic Therapy; Ticlopidine; Time Factors; Tissue Plasminogen Activator; Tomography, X-Ray Computed; Ultrasonography | 2003 |
[Carotid stenosis: diagnosis, patient selection, therapy].
Topics: Aged; Aged, 80 and over; Angiography, Digital Subtraction; Angioplasty, Balloon; Aspirin; Carotid Stenosis; Clopidogrel; Endarterectomy, Carotid; Fibrinolytic Agents; Forecasting; Humans; Life Expectancy; Magnetic Resonance Angiography; Patient Selection; Platelet Aggregation Inhibitors; Recurrence; Risk Factors; Stents; Stroke; Ticlopidine; Tomography, X-Ray Computed; Ultrasonography, Doppler, Duplex | 2003 |
Aspirin and stroke prevention.
Topics: Aspirin; Clopidogrel; Dipyridamole; Dose-Response Relationship, Drug; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Treatment Failure; Treatment Outcome | 2003 |
Role of antiplatelet drugs in the prevention of cardiovascular events.
Topics: Aspirin; Benzamidines; Clopidogrel; Coronary Artery Disease; Humans; Myocardial Infarction; Oximes; Piperidines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyridines; Stroke; Ticlopidine; Treatment Outcome | 2003 |
Aggrenox((R)) versus other pharmacotherapy in preventing recurrent stroke.
Topics: Aspirin; Aspirin, Dipyridamole Drug Combination; Clopidogrel; Cost-Benefit Analysis; Delayed-Action Preparations; Dipyridamole; Drug Combinations; Humans; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Secondary Prevention; Stroke; Ticlopidine | 2004 |
Recent clinical trial results with antiplatelet therapy: implications in stroke prevention.
Topics: Angina, Unstable; Aspirin; Clinical Trials as Topic; Clopidogrel; Humans; Myocardial Infarction; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Risk Factors; Risk Reduction Behavior; Stroke; Ticlopidine | 2004 |
Trials of newer approaches to anticoagulation in atrial fibrillation.
Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Azetidines; Benzylamines; Clopidogrel; Humans; International Normalized Ratio; Platelet Aggregation Inhibitors; Risk Factors; Stroke; Thrombin; Ticlopidine; Warfarin | 2004 |
The role of warfarin and aspirin in secondary prevention of stroke.
Topics: Anticoagulants; Aspirin; Clopidogrel; Heart Septal Defects, Atrial; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Treatment Outcome; Warfarin | 2004 |
[Interactions of statins with antithrombotic drugs].
Topics: Animals; Anticholesteremic Agents; Aspirin; Atorvastatin; Cardiovascular Diseases; Clopidogrel; Controlled Clinical Trials as Topic; Drug Interactions; Drug Therapy, Combination; Fibrinolytic Agents; Follow-Up Studies; Hemostasis; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Platelet Aggregation Inhibitors; Pravastatin; Primary Prevention; Pyrroles; Rats; Ticlopidine; Time Factors | 2004 |
Antiplatelet agents in atherothrombotic diseases.
Topics: Arteriosclerosis; Aspirin; Clopidogrel; Dipyridamole; Humans; Ischemia; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombosis; Ticlopidine | 2004 |
[Drug therapy for patients with unstable angina].
Topics: Abciximab; Adrenergic beta-Antagonists; Angina, Unstable; Antibodies, Monoclonal; Aspirin; Calcium Channel Blockers; Coronary Artery Bypass; Heparin; Humans; Immunoglobulin Fab Fragments; Intra-Aortic Balloon Pumping; Nitroglycerin; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Risk; Ticlopidine | 2004 |
Prevention of coronary heart disease with aspirin and clopidogrel: efficacy, safety, costs and cost-effectiveness.
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Disease; Cost-Benefit Analysis; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2004 |
Clopidogrel's role in the management of atherosclerotic disease: a focus on acute coronary syndromes.
Topics: Angina, Unstable; Angioplasty, Balloon, Coronary; Arteriosclerosis; Aspirin; Clinical Trials as Topic; Clopidogrel; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Pyridines; Stents; Ticlopidine; Treatment Outcome; Vascular Diseases | 2003 |
Antiplatelet treatment for secondary prevention of acute ischemic stroke and transient ischemic attacks: mechanisms, choices and possible emerging patterns of use.
Topics: Aspirin; Aspirin, Dipyridamole Drug Combination; Clopidogrel; Dipyridamole; Drug Combinations; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Secondary Prevention; Stroke; Ticlopidine | 2003 |
Atrial fibrillation: should we target platelets or the coagulation pathway?
Topics: Aspirin; Atrial Fibrillation; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Risk Assessment; Stroke; Thrombolytic Therapy; Ticlopidine; Venous Thrombosis; Warfarin | 2003 |
[The value of platelet inhibitors in the secondary prophylaxis of stroke -- a review].
Topics: Aspirin; Brain Ischemia; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Dose-Response Relationship, Drug; Humans; Platelet Aggregation Inhibitors; Secondary Prevention; Ticlopidine; Treatment Outcome | 2004 |
[EBM of cerebral infarction: message from mega-studies].
Topics: Anticoagulants; Aspirin; Azetidines; Benzylamines; Cerebral Infarction; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Meta-Analysis as Topic; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Secondary Prevention; Ticlopidine; Warfarin | 2003 |
Clopidogrel in the management of cerebrovascular events.
Topics: Arteriosclerosis; Aspirin; Clopidogrel; Drug Costs; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stroke; Thrombosis; Ticlopidine | 2004 |
[Treatment of ischemic heart disease with the platelet aggregation inhibitor clopidogrel].
Topics: Aspirin; Clopidogrel; Coronary Disease; Coronary Thrombosis; Drug Therapy, Combination; Humans; Myocardial Ischemia; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stents; Stroke; Ticlopidine | 2004 |
Clopidogrel: how good is it and how does it work?
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Endothelium, Vascular; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Recurrence; Ticlopidine; Treatment Outcome | 2004 |
Antiplatelet agents.
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Design; Drug Resistance; Drug Therapy, Combination; Humans; Meta-Analysis as Topic; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyridines; Ticlopidine | 2004 |
Antithrombotic drugs in vascular medicine: a historical perspective.
Topics: Administration, Oral; Anticoagulants; Aspirin; Blood Platelets; Clopidogrel; Endothelium, Vascular; Fibrinolytic Agents; Heparin; Heparin, Low-Molecular-Weight; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombosis; Ticlopidine | 2003 |
Combined antithrombotic therapy for acute coronary syndrome.
Topics: Administration, Oral; Angina, Unstable; Anticoagulants; Aspirin; Clopidogrel; Coronary Thrombosis; Dipyridamole; Drug Therapy, Combination; Fibrinolytic Agents; Heparin; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine | 2003 |
Antithrombotic treatment of NSTEMI/UAP. The interaction with PCI.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Fibrinolytic Agents; Heparin; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine | 2004 |
[Acute coronary syndromes without ST segment elevation].
Topics: Acute Disease; Adrenergic beta-Antagonists; Analgesics, Opioid; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Aspirin; Calcium Channel Blockers; Clopidogrel; Coronary Disease; Electrocardiography; Enoxaparin; Humans; Morphine; Myocardial Revascularization; Oxygen Inhalation Therapy; Patient Selection; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Risk Factors; Ticlopidine; Time Factors | 2004 |
Comparison of cilostazol and ticlopidine for one-month effectiveness and safety after elective coronary stenting.
Topics: Administration, Oral; Aspirin; Cilostazol; Coronary Restenosis; Coronary Stenosis; Coronary Vessels; Data Collection; Data Interpretation, Statistical; Death; Documentation; Drug Administration Schedule; Drug Therapy, Combination; Elective Surgical Procedures; Evaluation Studies as Topic; Humans; Japan; Medical Records; Myocardial Infarction; Odds Ratio; Stents; Tetrazoles; Ticlopidine; Time Factors; Treatment Outcome | 2004 |
Antiplatelet agents and anticoagulants for hypertension.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Clopidogrel; Humans; Hypertension; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Thromboembolism; Ticlopidine; Warfarin | 2004 |
Comparison of bilateral thoracic artery grafting with percutaneous coronary interventions in diabetic patients.
Topics: Abciximab; Aged; Angioplasty, Balloon; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Combined Modality Therapy; Coronary Artery Bypass; Coronary Disease; Diabetes Complications; Diltiazem; Eptifibatide; Female; Humans; Immunoglobulin Fab Fragments; Isosorbide Dinitrate; Life Tables; Male; Middle Aged; Peptides; Platelet Aggregation Inhibitors; Recurrence; Retrospective Studies; Stents; Survival Analysis; Thoracic Arteries; Ticlopidine; Treatment Outcome; Vascular Patency | 2004 |
Relationship between activated clotting time and ischemic or hemorrhagic complications: analysis of 4 recent randomized clinical trials of percutaneous coronary intervention.
Topics: Abciximab; Aged; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Aspirin; Blood Coagulation Tests; Clopidogrel; Comorbidity; Coronary Restenosis; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Hemorrhage; Heparin; Hirudins; Humans; Immunoglobulin Fab Fragments; Incidence; Male; Middle Aged; Multicenter Studies as Topic; Myocardial Infarction; Myocardial Ischemia; Peptide Fragments; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Recombinant Proteins; Retrospective Studies; Stents; Thrombophilia; Ticlopidine; Tirofiban; Tyrosine | 2004 |
Role of clopidogrel in unstable angina and non-ST-segment elevation myocardial infarction: from literature and guidelines to practice.
Topics: Angina, Unstable; Aspirin; Clopidogrel; Coronary Disease; Cost-Benefit Analysis; Hemorrhage; Humans; Middle Aged; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Risk Factors; Ticlopidine | 2004 |
Antiplatelet therapy in peripheral arterial disease.
Topics: Arterial Occlusive Diseases; Aspirin; Clopidogrel; Dipyridamole; Humans; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine; Treatment Outcome | 2004 |
Antithrombotic therapy for coronary artery disease: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.
Topics: Antithrombins; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease; Coronary Thrombosis; Electrocardiography; Evidence-Based Medicine; Fibrinolytic Agents; Heparin; Heparin, Low-Molecular-Weight; Humans; Myocardial Infarction; Randomized Controlled Trials as Topic; Risk Assessment; Ticlopidine | 2004 |
Thrombolysis and adjunctive therapy in acute myocardial infarction: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.
Topics: Aspirin; Clopidogrel; Contraindications; Drug Therapy, Combination; Electrocardiography; Evidence-Based Medicine; Fibrinolytic Agents; Heparin; Heparin, Low-Molecular-Weight; Humans; Infusions, Intravenous; Injections, Subcutaneous; Myocardial Infarction; Randomized Controlled Trials as Topic; Risk Assessment; Secondary Prevention; Thrombolytic Therapy; Ticlopidine | 2004 |
Antithrombotic therapy during percutaneous coronary intervention: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.
Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clopidogrel; Contraindications; Coronary Restenosis; Coronary Stenosis; Drug Therapy, Combination; Evidence-Based Medicine; Fibrinolytic Agents; Heparin; Hirudins; Humans; Immunoglobulin Fab Fragments; Peptide Fragments; Practice Guidelines as Topic; Pyridines; Recombinant Proteins; Risk Assessment; Stents; Ticlopidine | 2004 |
Antithrombotic therapy in patients with saphenous vein and internal mammary artery bypass grafts: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.
Topics: Aspirin; Clopidogrel; Contraindications; Coronary Artery Bypass; Coronary Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; Evidence-Based Medicine; Fibrinolytic Agents; Graft Occlusion, Vascular; Humans; Internal Mammary-Coronary Artery Anastomosis; Myocardial Infarction; Randomized Controlled Trials as Topic; Risk Assessment; Ticlopidine; Veins | 2004 |
Antithrombotic therapy in peripheral arterial occlusive disease: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.
Topics: Arterial Occlusive Diseases; Aspirin; Cilostazol; Clopidogrel; Contraindications; Evidence-Based Medicine; Extremities; Fibrinolytic Agents; Heparin; Humans; Intermittent Claudication; Ischemia; Randomized Controlled Trials as Topic; Risk Assessment; Tetrazoles; Thromboembolism; Ticlopidine; Vitamin K | 2004 |
Aspirin and clopidogrel: efficacy, safety, and the issue of drug resistance.
Topics: Aspirin; Clopidogrel; Drug Resistance; Humans; Ticlopidine; Treatment Failure; Treatment Outcome; Venous Thrombosis | 2004 |
Clinical effectiveness and cost-effectiveness of clopidogrel and modified-release dipyridamole in the secondary prevention of occlusive vascular events: a systematic review and economic evaluation.
Topics: Aspirin; Clopidogrel; Cost-Benefit Analysis; Delayed-Action Preparations; Diarrhea; Dipyridamole; Drug Costs; Drug Eruptions; Dyspepsia; Evidence-Based Medicine; Hemorrhage; Humans; Ischemia; Models, Econometric; Nausea; Platelet Aggregation Inhibitors; Research Design; Risk Factors; Ticlopidine; Treatment Outcome; Vascular Diseases; Vomiting | 2004 |
Clopidogrel used in combination with aspirin compared with aspirin alone in the treatment of non-ST-segment-elevation acute coronary syndromes: a systematic review and economic evaluation.
Topics: Acute Disease; Aspirin; Clopidogrel; Coronary Disease; Cost-Benefit Analysis; Drug Therapy, Combination; Electrocardiography; Humans; Platelet Aggregation Inhibitors; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Ticlopidine; Treatment Outcome | 2004 |
The results of MATCH: light or heat?
Topics: Aspirin; Clopidogrel; Controlled Clinical Trials as Topic; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Stroke; Ticlopidine | 2004 |
Oral antiplatelet therapy in cerebrovascular disease, coronary artery disease, and peripheral arterial disease.
Topics: Administration, Oral; Angina Pectoris; Arteriosclerosis; Aspirin; Cerebrovascular Disorders; Clopidogrel; Coronary Artery Disease; Dipyridamole; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Stroke; Thrombosis; Ticlopidine | 2004 |
Comparative benefits of clopidogrel and aspirin in high-risk patient populations: lessons from the CAPRIE and CURE studies.
Topics: Angina, Unstable; Aspirin; Clopidogrel; Comorbidity; Diabetes Mellitus; Humans; Hypercholesterolemia; Myocardial Ischemia; Platelet Aggregation Inhibitors; Recurrence; Risk; Ticlopidine | 2004 |
Platelet function testing in cardiovascular diseases.
Topics: Angina, Unstable; Aspirin; Cardiovascular Diseases; Case Management; Clopidogrel; Drug Resistance; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombosis; Ticlopidine; Treatment Outcome | 2004 |
[Cardiovascular risk in diabetes--diagnostic and therapeutic aspects].
Topics: Abciximab; Angioplasty, Balloon, Coronary; Angiotensin-Converting Enzyme Inhibitors; Antibodies, Monoclonal; Aspirin; Blood Glucose; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Diabetes Complications; Diabetes Mellitus; Follow-Up Studies; Glucose Tolerance Test; Humans; Hypolipidemic Agents; Immunoglobulin Fab Fragments; Insulin; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Primary Prevention; Risk; Risk Factors; Stents; Ticlopidine; Time Factors | 2004 |
Angina (unstable).
Topics: Angina, Unstable; Aspirin; Cardiac Catheterization; Heparin, Low-Molecular-Weight; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine; Warfarin | 2003 |
Prevention of cardiovascular events in diabetes.
Topics: Angioplasty, Balloon; Antihypertensive Agents; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Bypass; Diabetic Angiopathies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypertension; Hypolipidemic Agents; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Smoking Cessation; Ticlopidine | 2003 |
G13-mediated signaling as a potential target for antiplatelet drugs.
Topics: Animals; Aspirin; Blood Platelets; Clopidogrel; Forecasting; Germany; GTP-Binding Protein alpha Subunits, G12-G13; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Signal Transduction; Ticlopidine | 2004 |
New possibilities in anticoagulant management of atrial fibrillation.
Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Azetidines; Benzylamines; Clopidogrel; Humans; Oligosaccharides; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Warfarin | 2004 |
Stroke: advances in therapy.
Topics: Aspirin; Carotid Stenosis; Clinical Trials as Topic; Clopidogrel; Coronary Artery Bypass; Drug Therapy, Combination; Endarterectomy, Carotid; Fibrinolytic Agents; Humans; Myocardial Infarction; Plasminogen Activators; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stents; Stroke; Ticlopidine; Treatment Outcome | 2005 |
Controversies of oral antiplatelet therapy in acute coronary syndromes and percutaneous coronary intervention.
Topics: Administration, Oral; Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Disease; Drug Synergism; Humans; Myocardial Infarction; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine | 2004 |
Cilostazol, clopidogrel or ticlopidine to prevent sub-acute stent thrombosis: a meta-analysis of randomized trials.
Topics: Anticoagulants; Aspirin; Cilostazol; Clopidogrel; Coronary Thrombosis; Drug Therapy, Combination; Humans; Odds Ratio; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stents; Tetrazoles; Ticlopidine; Warfarin | 2004 |
Secondary prevention of recurrent stroke.
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Diabetes Complications; Endarterectomy; Endarterectomy, Carotid; Fibrinolytic Agents; Homocysteine; Humans; Platelet Aggregation Inhibitors; Risk; Risk Factors; Secondary Prevention; Stents; Stroke; Ticlopidine; Vitamin B Complex | 2005 |
[Aspirin: recent advances in cardiovascular prevention].
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Primary Prevention; Ticlopidine | 2004 |
Stroke prevention. MATCHing therapy to the patient with TIA.
Topics: Aspirin; Clopidogrel; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Recurrence; Risk Factors; Stroke; Ticlopidine | 2005 |
Combination antiplatelet agents in ischemic cerebrovascular disease.
Topics: Aspirin; Brain Ischemia; Cardiovascular Diseases; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine | 2005 |
[Antithrombotic therapy after myocardial infarction: arguments for the use of acetylsalicylic acid and coumarin derivatives].
Topics: Anticoagulants; Aspirin; Clopidogrel; Coumarins; Death, Sudden, Cardiac; Fibrinolytic Agents; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk Factors; Secondary Prevention; Stroke; Ticlopidine | 2005 |
[Antithrombotic therapy of acute coronary syndromes].
Topics: Acute Disease; Aspirin; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Fibrinolytic Agents; Heparin, Low-Molecular-Weight; Humans; Thrombolytic Therapy; Ticlopidine | 2005 |
Adverse effects and drug interactions of antithrombotic agents used in prevention of ischaemic stroke.
Topics: Anticoagulants; Aspirin; Clopidogrel; Dipyridamole; Drug Interactions; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Salicylates; Stroke; Ticlopidine; Warfarin | 2005 |
What is the risk of stent thrombosis associated with the use of paclitaxel-eluting stents for percutaneous coronary intervention?: a meta-analysis.
Topics: Aged; Angioplasty, Balloon, Coronary; Antineoplastic Agents, Phytogenic; Aspirin; Blood Vessel Prosthesis Implantation; Clopidogrel; Coated Materials, Biocompatible; Coronary Artery Disease; Coronary Thrombosis; Female; Humans; Male; Middle Aged; Paclitaxel; Platelet Aggregation Inhibitors; Postoperative Complications; Risk Factors; Stents; Ticlopidine; Treatment Outcome | 2005 |
Optimal antithrombotic treatment for percutaneous coronary intervention.
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Blood Coagulation; Clinical Trials as Topic; Clopidogrel; Heparin, Low-Molecular-Weight; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyridines; Stents; Thrombin; Thrombosis; Ticlopidine; Treatment Outcome | 2005 |
Efficacy and costs of secondary prevention with antiplatelets after ischaemic stroke.
Topics: Aspirin; Brain Ischemia; Clopidogrel; Cost-Benefit Analysis; Dipyridamole; Health Care Costs; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2005 |
Optimal duration of antiplatelet therapy in recipients of coronary drug-eluting stents.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Disease; Drug Administration Schedule; Humans; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2005 |
Adding aspirin to clopidogrel after TIA and ischemic stroke: benefits do not match risks.
Topics: Aspirin; Brain Ischemia; Clopidogrel; Drug Synergism; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Risk Assessment; Secondary Prevention; Stroke; Thromboembolism; Ticlopidine | 2005 |
Clopidogrel and ticlopidine: P2Y12 adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis.
Topics: Adenosine Diphosphate; Animals; Arteriosclerosis; Aspirin; Clinical Trials as Topic; Clopidogrel; Cohort Studies; Double-Blind Method; Drug Resistance; Fibrinolytic Agents; Forecasting; Humans; Membrane Proteins; Meta-Analysis as Topic; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Pyridines; Randomized Controlled Trials as Topic; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thrombophilia; Thrombosis; Ticlopidine | 2005 |
Pharmacology of CS-747 (prasugrel, LY640315), a novel, potent antiplatelet agent with in vivo P2Y12 receptor antagonist activity.
Topics: Adenosine Diphosphate; Adult; Animals; Aspirin; Biotransformation; Clinical Trials, Phase I as Topic; Clopidogrel; Collagen; Drug Evaluation, Preclinical; Drug Synergism; Fibrinolytic Agents; Hemostasis; Humans; Male; Membrane Proteins; Molecular Structure; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Prodrugs; Purinergic P2 Receptor Antagonists; Pyridines; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thiophenes; Thrombin; Thrombosis; Ticlopidine | 2005 |
The value of clopidogrel versus aspirin in reducing atherothrombotic events: the CAPRIE study.
Topics: Arterial Occlusive Diseases; Aspirin; Clopidogrel; Cost-Benefit Analysis; Humans; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Ticlopidine | 2004 |
The value of clopidogrel in addition to standard therapy in reducing atherothrombotic events.
Topics: Angioplasty, Balloon, Coronary; Arterial Occlusive Diseases; Aspirin; Benchmarking; Clopidogrel; Drug Therapy, Combination; Humans; Ticlopidine | 2004 |
Issues in the management of antiplatelet therapy in patients undergoing surgical revascularization. A roundtable discussion.
Topics: Angina, Unstable; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Combined Modality Therapy; Coronary Artery Bypass; Coronary Stenosis; Female; Humans; Male; Myocardial Revascularization; Platelet Aggregation Inhibitors; Prognosis; Radiography; Risk Assessment; Stents; Survival Rate; Ticlopidine; Treatment Outcome | 2005 |
[Antithrombotic therapy during percutaneous coronary interventions].
Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clopidogrel; Fibrinolytic Agents; Heparin; Humans; Immunoglobulin Fab Fragments; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine | 2005 |
[Oral antithrombotic therapy in primary and secondary prevention].
Topics: Animals; Aspirin; Clopidogrel; Fibrinolytic Agents; Humans; Primary Prevention; Secondary Prevention; Thrombosis; Ticlopidine | 2005 |
Platelet inhibition in percutaneous coronary interventions.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Thrombosis; Humans; Platelet Aggregation Inhibitors; Premedication; Ticlopidine | 2005 |
Clopidogrel in acute coronary syndrome: when, how much, how long?
Topics: Acute Disease; Angina, Unstable; Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; Germany; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Practice Patterns, Physicians'; Syndrome; Ticlopidine; Treatment Outcome | 2005 |
[Mechanism and drug treatment of atherothrombosis].
Topics: Anticoagulants; Arteriosclerosis; Aspirin; C-Reactive Protein; CD40 Antigens; Clopidogrel; Drug Therapy, Combination; Fibrinolytic Agents; Heparin; Heparin, Low-Molecular-Weight; Humans; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombolytic Therapy; Thrombosis; Ticlopidine | 2005 |
Avoiding central nervous system bleeding during antithrombotic therapy: recent data and ideas.
Topics: Administration, Oral; Age Factors; Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Blood Pressure; Brain Ischemia; Cerebral Hemorrhage; Clinical Trials as Topic; Clopidogrel; Female; Fibrinolytic Agents; Humans; International Normalized Ratio; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine; Warfarin | 2005 |
Aspirin and clopidogrel: a sweeping combination in cardiology.
Topics: Aspirin; Cardiology; Cardiovascular Diseases; Clopidogrel; Humans; Ticlopidine | 2005 |
Resistance to antiplatelet therapy.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Clopidogrel; Coronary Disease; Drug Tolerance; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2005 |
Antiplatelet therapy in neuroendovascular therapeutics.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Humans; Intracranial Aneurysm; Intracranial Thrombosis; Platelet Aggregation Inhibitors; Radiography; Stents; Ticlopidine | 2005 |
Female-specific aspects in the pharmacotherapy of chronic cardiovascular diseases.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Aspirin; Calcium Channel Blockers; Cardiovascular Agents; Cardiovascular Diseases; Chronic Disease; Clopidogrel; Digitalis Glycosides; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Sex Factors; Ticlopidine; Women's Health | 2005 |
Meta-analysis of trials comparing oral anticoagulation and aspirin versus dual antiplatelet therapy after coronary stenting. Clues for the management of patients with an indication for long-term anticoagulation undergoing coronary stenting.
Topics: Administration, Oral; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coronary Stenosis; Drug Therapy, Combination; Follow-Up Studies; Humans; Long-Term Care; Multicenter Studies as Topic; Myocardial Infarction; Myocardial Revascularization; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stents; Ticlopidine; Treatment Outcome | 2005 |
Balancing the benefit and risk of oral antiplatelet agents in coronary artery bypass surgery.
Topics: Administration, Oral; Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Coronary Artery Bypass; Graft Occlusion, Vascular; Humans; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Risk Assessment; Ticlopidine | 2005 |
Therapeutic approaches in arterial thrombosis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Atherosclerosis; Blood Platelets; Clopidogrel; Coronary Thrombosis; Disease Models, Animal; Disease Progression; Fibrinolytic Agents; Humans; Mice; Models, Biological; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyridines; Risk; Signal Transduction; Thrombosis; Ticlopidine; Time Factors | 2005 |
Determinants of the interindividual variability in response to antiplatelet drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Clopidogrel; Drug Interactions; Drug Resistance; Humans; Models, Biological; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Risk; Thrombosis; Ticlopidine; Treatment Outcome | 2005 |
Antiplatelet agents in patients undergoing percutaneous coronary intervention: how many and how much?
Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clinical Trials as Topic; Clopidogrel; Eptifibatide; Hirudins; Humans; Immunoglobulin Fab Fragments; Peptide Fragments; Peptides; Platelet Aggregation Inhibitors; Recombinant Proteins; Ticlopidine; Tirofiban; Tyrosine | 2005 |
Antiplatelet therapy in anticoagulated patients requiring coronary intervention.
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Risk Factors; Stents; Thromboembolism; Ticlopidine; Warfarin | 2005 |
Review of antiplatelet therapy in secondary prevention of cerebrovascular events: a need for direct comparisons between antiplatelet agents.
Topics: Aspirin; Clopidogrel; Dipyridamole; Humans; Platelet Aggregation Inhibitors; Recurrence; Salicylates; Stroke; Ticlopidine | 2005 |
[Triplex antithrombotic therapy after coronary-stent implantation (that is absent from recommendation)].
Topics: Aspirin; Clopidogrel; Coronary Restenosis; Coronary Stenosis; Coronary Vessels; Coumarins; Drug Therapy, Combination; Fibrinolytic Agents; Heparin, Low-Molecular-Weight; Humans; Secondary Prevention; Stents; Ticlopidine | 2005 |
[The new antithrombotic agents].
Topics: Administration, Oral; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Azetidines; Benzylamines; Clopidogrel; Fibrinolytic Agents; Glycine; Hirudins; Humans; Injections, Subcutaneous; Platelet Aggregation Inhibitors; Polysaccharides; Prodrugs; Randomized Controlled Trials as Topic; Stents; Thrombosis; Ticlopidine; Time Factors; Venous Thrombosis | 2005 |
[Preventing cerebrovascular accidents during atrial fibrillation].
Topics: Administration, Oral; Age Factors; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Aspirin; Atrial Fibrillation; Azetidines; Benzylamines; Clopidogrel; Drug Therapy, Combination; Electric Countershock; Humans; Hypolipidemic Agents; Incidence; Injections, Subcutaneous; Middle Aged; Oligosaccharides; Placebos; Platelet Aggregation Inhibitors; Prevalence; Prodrugs; Randomized Controlled Trials as Topic; Recurrence; Risk Factors; Stroke; Ticlopidine; Warfarin | 2005 |
Effect on platelet function of cilostazol, clopidogrel, and aspirin, each alone or in combination.
Topics: Aspirin; Bleeding Time; Blood Platelets; Cilostazol; Clopidogrel; Drug Therapy, Combination; Humans; Intermittent Claudication; Platelet Aggregation; Platelet Aggregation Inhibitors; Tetrazoles; Ticlopidine; Treatment Outcome | 2005 |
[Current concepts of the antiplatelet and anticoagulant treatment in the prevention of stroke].
Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Brain Ischemia; Clinical Trials as Topic; Clopidogrel; Delayed-Action Preparations; Dipyridamole; Drug Therapy, Combination; Evidence-Based Medicine; Fibrinolytic Agents; Humans; Multicenter Studies as Topic; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Recurrence; Stroke; Ticlopidine; Warfarin | 2005 |
Upper gastrointestinal haemorrhage complicating antiplatelet treatment with aspirin and/or clopidogrel: where we are now?
Topics: Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Esomeprazole; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine | 2006 |
Aspirin and clopidogrel resistance: an emerging clinical entity.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Drug Resistance; Female; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2006 |
[Evidence-based medicine in antithrombotic therapy].
Topics: Aspirin; Evidence-Based Medicine; Fibrinolytic Agents; Heparin; Humans; Thrombolytic Therapy; Thrombosis; Ticlopidine; Warfarin | 2005 |
Best evidence topic report. Clopidogrel plus aspirin or aspirin alone in unstable angina.
Topics: Angina, Unstable; Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2006 |
Selective serotonin reuptake inhibitors and increased bleeding risk: are we missing something?
Topics: Aspirin; Clopidogrel; Depressive Disorder; Drug Interactions; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Selective Serotonin Reuptake Inhibitors; Ticlopidine | 2006 |
[Haemostasis. Aspirin and clopidogrel platelet resistances].
Topics: Aspirin; Clopidogrel; Drug Resistance; Hemostasis; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2006 |
Emerging drugs in peripheral arterial disease.
Topics: Administration, Oral; Anticoagulants; Arterial Occlusive Diseases; Arteries; Aspirin; Clopidogrel; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Intermittent Claudication; Ischemic Attack, Transient; Myocardial Infarction; Pentoxifylline; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Ticlopidine; Tissue Plasminogen Activator; Vasodilator Agents | 2006 |
[Cardiological (pharmaco)therapy and dental practice].
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Thrombosis; Defibrillators, Implantable; Heart Valve Prosthesis; Humans; Oral Surgical Procedures; Platelet Aggregation Inhibitors; Risk Factors; Secondary Prevention; Ticlopidine | 2006 |
Gastrointestinal complications of dual antiplatelet therapy.
Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Duodenal Ulcer; Endoscopy, Digestive System; Gastrointestinal Diseases; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine | 2006 |
[Secondary prevention of acute coronary syndromes: are we following correctly the guidelines?].
Topics: Acute Disease; Adrenergic beta-Antagonists; Algorithms; Angina, Unstable; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Chest Pain; Clinical Trials as Topic; Clopidogrel; Cost-Benefit Analysis; Diagnosis, Differential; Electrocardiography; Evidence-Based Medicine; Fibrinolytic Agents; Forecasting; Guideline Adherence; Humans; Hypolipidemic Agents; Myocardial Infarction; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Prognosis; Risk Assessment; Syndrome; Ticlopidine | 2006 |
Is clopidogrel cardiovascular medicine's double-edged sword?
Topics: Aspirin; Clopidogrel; Coronary Artery Bypass, Off-Pump; Coronary Disease; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Vascular Diseases | 2006 |
Aspirin and clopidogrel resistance.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Resistance, Multiple; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2006 |
[Anti-platelet drugs (aspirin, ticlopidine, etc)].
Topics: Angina, Unstable; Angioplasty, Balloon, Coronary; Aspirin; Clinical Trials as Topic; Humans; Meta-Analysis as Topic; Myocardial Infarction; Platelet Aggregation Inhibitors; Stroke; Syndrome; Ticlopidine | 2006 |
[Adding aspirin to clopidogrel in secondary prevention of ischemic stroke: no significant benefits. Results of the Match study].
Topics: Aspirin; Cerebral Infarction; Clopidogrel; Drug Therapy, Combination; Follow-Up Studies; Hemorrhage; Hospitalization; Humans; Ischemic Attack, Transient; Multicenter Studies as Topic; Myocardial Infarction; Patient Selection; Placebos; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Ticlopidine; Time Factors | 2006 |
Angina (unstable).
Topics: Angina, Unstable; Aspirin; Cardiac Catheterization; Clopidogrel; Heparin, Low-Molecular-Weight; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine; Warfarin | 2005 |
Masterclass series in peripheral arterial disease. Antiplatelet therapy for peripheral arterial disease and claudication.
Topics: Aspirin; Atherosclerosis; Clopidogrel; Drug Therapy, Combination; Humans; Intermittent Claudication; Lower Extremity; Meta-Analysis as Topic; Peripheral Vascular Diseases; Phthalic Acids; Platelet Aggregation; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Ticlopidine | 2006 |
[Dual antithrombotic therapy after implantation of coronary stents].
Topics: Aspirin; Clopidogrel; Coronary Stenosis; Dose-Response Relationship, Drug; Drug Synergism; Humans; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2006 |
Clopidogrel resistance: myth or reality?
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine | 2006 |
Aspirin resistance: does it exist and is it an important clinical problem?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Resistance; Humans; Myeloproliferative Disorders; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Thrombosis; Ticlopidine | 2006 |
Clopidogrel in the treatment of ischaemic heart disease.
Topics: Adolescent; Adult; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine | 2006 |
Antiplatelet therapy in populations at high risk of atherothrombosis.
Topics: Arteriosclerosis; Aspirin; Chemoprevention; Clopidogrel; Drug Therapy, Combination; Embolism, Cholesterol; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Thromboembolism; Ticlopidine | 2006 |
MATCH results: implications for the internist.
Topics: Aspirin; Atherosclerosis; Clopidogrel; Controlled Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Europe; Hemorrhage; Humans; Ischemic Attack, Transient; Multicenter Studies as Topic; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stroke; Thrombosis; Ticlopidine; Treatment Failure; United States | 2006 |
[Atheromatosis of the thoracic aorta and risk of stroke].
Topics: Anticoagulants; Aorta, Thoracic; Aortic Diseases; Aspirin; Atherosclerosis; Clopidogrel; Controlled Clinical Trials as Topic; Echocardiography, Transesophageal; Fibrinolytic Agents; Follow-Up Studies; Humans; Hypolipidemic Agents; Meta-Analysis as Topic; Odds Ratio; Platelet Aggregation Inhibitors; Prognosis; Recurrence; Risk Factors; Stroke; Ticlopidine; Time Factors; Warfarin | 2006 |
Prevention of vascular events in patients with cerebrovascular disease: efficacy and appropriate duration of antiplatelet therapy.
Topics: Aspirin; Cerebrovascular Disorders; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2006 |
Clopidogrel: a pharmacoeconomic review of its use in patients with non-ST elevation acute coronary syndromes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Coronary Disease; Cost-Benefit Analysis; Economics, Pharmaceutical; Humans; Markov Chains; Platelet Aggregation Inhibitors; Prescription Fees; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Ticlopidine | 2006 |
Antiplatelet resistance with aspirin and clopidogrel: is it real and does it matter?
Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine | 2006 |
Aortic arch atheroma and the risk of stroke.
Topics: Aorta, Thoracic; Aspirin; Atherosclerosis; Clopidogrel; History, 18th Century; Humans; Risk Factors; Stroke; Ticlopidine | 2006 |
Systematic review and meta-analysis of adverse events of low-dose aspirin and clopidogrel in randomized controlled trials.
Topics: Aspirin; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2006 |
[Resistance to acetylsalicylic acid and clopidogrel: current status].
Topics: Aspirin; Clopidogrel; Drug Monitoring; Drug Resistance; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; Vascular Diseases | 2006 |
Secondary prevention of ischaemic cardiac events.
Topics: Adrenergic beta-Antagonists; Angioplasty, Balloon, Coronary; Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Antihypertensive Agents; Aspirin; Clopidogrel; Coronary Artery Bypass; Diet; Drug Therapy, Combination; Estrogen Replacement Therapy; Exercise; Female; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Myocardial Ischemia; Platelet Aggregation Inhibitors; Smoking Cessation; Ticlopidine | 2006 |
Prevention of cardiovascular events in diabetes.
Topics: Angioplasty, Balloon; Antihypertensive Agents; Aspirin; Bezafibrate; Cardiovascular Diseases; Clopidogrel; Diabetic Angiopathies; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperglycemia; Hyperlipidemias; Hypertension; Hypolipidemic Agents; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Smoking Cessation; Ticlopidine | 2006 |
Does a coxib-associated thrombotic risk limit the clinical use of the compounds as analgesic, antiinflammatory drugs? Arguments against.
Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Cardiovascular Diseases; Clopidogrel; Cyclooxygenase 2 Inhibitors; Drug Interactions; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Patient Selection; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Assessment; Thrombosis; Ticlopidine | 2006 |
Possible mechanisms of drug-induced aspirin and clopidogrel resistance.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Drug Resistance; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Platelet Aggregation Inhibitors; Ticlopidine | 2006 |
Aspirin and clopidogrel resistance: consideration and management.
Topics: Adenosine; Adenosine Monophosphate; Angioplasty, Balloon, Coronary; Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Restenosis; Drug Resistance; Humans; Membrane Proteins; Myocardial Ischemia; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Thiophenes; Ticagrelor; Ticlopidine | 2006 |
Current developments in anti-platelet therapy.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cerebral Infarction; Clopidogrel; Drug Resistance; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine | 2006 |
The safety and efficacy of aspirin and clopidogrel as a combination treatment in patients with coronary heart disease.
Topics: Aspirin; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2006 |
Antiplatelet drug resistance and drug-drug interactions: Role of cytochrome P450 3A4.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Drug Interactions; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2006 |
[Are the NSAIDs able to compromising the cardio-preventive efficacy of aspirin?].
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Cyclooxygenase Inhibitors; Drug Interactions; Follow-Up Studies; Humans; Ibuprofen; MEDLINE; Middle Aged; Multivariate Analysis; Naproxen; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk; Thromboxane B2; Ticlopidine; Time Factors | 2006 |
Clinical applications of antiplatelet therapy.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Disease; Cyclooxygenase Inhibitors; Drug Resistance; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Pyridines; Ticlopidine | 2006 |
[Platelet-function inhibitors in the secondary prevention of ischemic stroke].
Topics: Aged; Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; Middle Aged; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Risk Factors; Secondary Prevention; Stroke; Ticlopidine | 2006 |
Aspirin resistance or variable response or both?
Topics: Aspirin; Clopidogrel; Drug Resistance; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine | 2006 |
Clopidogrel response variability, resistance, or both?
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Resistance; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Function Tests; Research Design; Ticlopidine | 2006 |
Prasugrel.
Topics: Adenosine Diphosphate; Animals; Aspirin; Clinical Trials, Phase I as Topic; Clinical Trials, Phase III as Topic; Clopidogrel; Collagen; Coronary Disease; Drug Evaluation, Preclinical; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Drugs, Investigational; Humans; Piperazines; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Prodrugs; Purinergic P2 Receptor Antagonists; Pyridines; Rats; Receptors, Purinergic P2Y12; Thiophenes; Ticlopidine | 2006 |
[Antithrombotic treatment of acute coronary syndromes without ST-segment elevation].
Topics: Abciximab; Antibodies, Monoclonal; Aspirin; Clopidogrel; Eptifibatide; Fibrinolytic Agents; Humans; Immunoglobulin Fab Fragments; Myocardial Infarction; Peptides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Risk Factors; Syndrome; Ticlopidine; Tirofiban; Tyrosine | 2006 |
Clopidogrel resistance?
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Humans; Membrane Proteins; Models, Biological; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Ticlopidine | 2007 |
Drug insight: antithrombotic therapy after percutaneous coronary intervention in patients with an indication for anticoagulation.
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Heart Valve Prosthesis Implantation; Heparin; Humans; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Practice Guidelines as Topic; Risk Factors; Stents; Thrombosis; Ticlopidine; Venous Thrombosis; Warfarin | 2006 |
[Antiplatelet agents--problem for cardiac surgeon].
Topics: Anticoagulants; Aspirin; Coronary Thrombosis; Dipyridamole; Fibrinolytic Agents; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Risk Factors; Ticlopidine | 2006 |
Evolving management of ST-segment elevation myocardial infarction: update on recent data.
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Fibrinolytic Agents; Heparin; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Practice Guidelines as Topic; Societies, Medical; Thrombolytic Therapy; Ticlopidine; United States | 2006 |
Identification of and management approaches for the high-risk patient.
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Artery Bypass; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Thromboembolism; Ticlopidine | 2006 |
Clopidogrel bisulfate: in ST-segment elevation myocardial infarction.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine | 2006 |
Stroke and the statistics of the aspirin/clopidogrel secondary prevention trials.
Topics: Aspirin; Clinical Protocols; Clinical Trials as Topic; Clopidogrel; Data Interpretation, Statistical; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Reproducibility of Results; Stroke; Ticlopidine; Treatment Outcome | 2007 |
Evolving perspectives on clopidogrel in the treatment of ischemic stroke.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Research Design; Secondary Prevention; Stroke; Ticlopidine; Treatment Outcome | 2006 |
The relationship of platelet reactivity to the occurrence of post-stenting ischemic events: emergence of a new cardiovascular risk factor.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Clopidogrel; Combined Modality Therapy; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Humans; Myocardial Infarction; Myocardial Ischemia; Patient Selection; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Risk Assessment; Risk Factors; Stents; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2006 |
Accelerating time to reperfusion in acute myocardial infarction: prehospital and emergency department strategies, systems of care, and pharmacologic interventions.
Topics: Adrenergic beta-Antagonists; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Blood Platelets; Cardiovascular Agents; Clopidogrel; Community Health Services; Critical Pathways; Emergency Medical Services; Emergency Service, Hospital; Fibrinolytic Agents; Health Services Accessibility; Heparin; Humans; Myocardial Infarction; Patient Care Team; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Program Development; Ticlopidine; Time Factors; Treatment Outcome; Triage; United States | 2006 |
Measuring antiplatelet drug effects in the laboratory.
Topics: Aspirin; Blood Platelets; Clopidogrel; Drug Resistance; Humans; Laboratories; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine | 2007 |
[Antiplatelet drugs and intraoperative hemorrhage].
Topics: Algorithms; Aspirin; Blood Loss, Surgical; Clopidogrel; Coronary Thrombosis; Drug Therapy, Combination; Humans; Intraoperative Period; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Risk Assessment; Ticlopidine | 2006 |
Clinical update on the therapeutic use of clopidogrel: treatment of acute ST-segment elevation myocardial infarction (STEMI).
Topics: Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Coronary Artery Bypass; Drug Resistance; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Ticlopidine; Treatment Outcome | 2006 |
Oral antiplatelet therapy for percutaneous coronary revascularization.
Topics: Administration, Oral; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Combined Modality Therapy; Coronary Disease; Coronary Thrombosis; Dose-Response Relationship, Drug; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyridines; Ticlopidine | 2007 |
Current management of transient ischemic attack.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Endarterectomy, Carotid; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Prognosis; Stents; Stroke; Ticlopidine | 2007 |
Role of clopidogrel in managing atherothrombotic cardiovascular disease.
Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Administration Schedule; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2007 |
Secondary prevention of stroke and transient ischemic attack: is more platelet inhibition the answer?
Topics: Aspirin; Atherosclerosis; Cilostazol; Clinical Trials as Topic; Clopidogrel; Coronary Disease; Dipyridamole; Disease Susceptibility; Drug Interactions; Drug Therapy, Combination; Dyslipidemias; Hemorrhage; Humans; Ischemic Attack, Transient; Multicenter Studies as Topic; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Recurrence; Stroke; Tetrazoles; Ticlopidine; Treatment Outcome; Vasodilator Agents | 2007 |
[Coronary stents, dual antiplatelet therapy and peri-operative problems].
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Humans; Perioperative Care; Platelet Aggregation Inhibitors; Platelet Function Tests; Stents; Thrombosis; Ticlopidine | 2007 |
Antiplatelet therapy in the treatment of atherothrombotic disease: considering the evidence.
Topics: Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Comorbidity; Drug Therapy, Combination; Evidence-Based Medicine; Female; Humans; Male; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Ticlopidine | 2007 |
[Stents in interventional cardiology].
Topics: Aged; Angioplasty, Balloon, Coronary; Anti-Bacterial Agents; Anti-Inflammatory Agents; Aspirin; Clopidogrel; Coronary Restenosis; Coronary Thrombosis; Diabetes Complications; Drug Delivery Systems; Drug Therapy, Combination; Fibrinolytic Agents; Follow-Up Studies; Humans; Immunosuppressive Agents; Middle Aged; Platelet Aggregation Inhibitors; Prednisolone; Randomized Controlled Trials as Topic; Risk Factors; Sirolimus; Stents; Ticlopidine; Time Factors; Treatment Outcome | 2007 |
Significance of aspirin and clopidogrel resistance in patients undergoing percutaneous coronary interventions.
Topics: Angioplasty, Balloon, Coronary; Animals; Aspirin; Blood Platelets; Clopidogrel; Drug Interactions; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2007 |
Variable platelet response to aspirin and clopidogrel in atherothrombotic disease.
Topics: Adenosine Diphosphate; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Atherosclerosis; Biomarkers; Biotransformation; Blood Coagulation Tests; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Interactions; Drug Resistance; Hemorrhage; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Randomized Controlled Trials as Topic; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Thrombosis; Thromboxane A2; Thromboxane B2; Ticlopidine; Treatment Failure | 2007 |
Clinical aspects of platelet inhibitors and thrombus formation.
Topics: Aspirin; Atherosclerosis; Blood Platelets; Cardiovascular Diseases; Cilostazol; Clopidogrel; Dipyridamole; Drug Resistance; Humans; Pentanoic Acids; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Purinergic P2 Receptor Antagonists; Pyridines; Receptor, PAR-1; Stents; Tetrazoles; Thrombosis; Thromboxanes; Ticlopidine | 2007 |
Antiplatelet therapy for atherothrombotic disease: an update for the primary care physician.
Topics: Anticoagulants; Aspirin; Atherosclerosis; Clopidogrel; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Primary Health Care; Recurrence; Risk Assessment; Stroke; Syndrome; Thrombosis; Ticlopidine | 2007 |
[Very late intrastent thrombosis--at 27 months!].
Topics: Aspirin; Clopidogrel; Coronary Thrombosis; Fatal Outcome; Flurbiprofen; Follow-Up Studies; Hernia, Inguinal; Humans; Laparoscopy; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Stents; Ticlopidine | 2007 |
[Dual platelet aggregation inhibition in coronary artery stent implantation--what is evidence-based?].
Topics: Aspirin; Clopidogrel; Coronary Thrombosis; Coronary Vessels; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Stents; Ticlopidine; Time Factors | 2007 |
The role of clopidogrel in the management of ischemic heart disease.
Topics: Aspirin; Clopidogrel; Humans; Myocardial Ischemia; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stents; Ticlopidine | 2007 |
Adjusted indirect meta-analysis of aspirin plus warfarin at international normalized ratios 2 to 3 versus aspirin plus clopidogrel after acute coronary syndromes.
Topics: Anticoagulants; Aspirin; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Humans; International Normalized Ratio; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Assessment; Syndrome; Ticlopidine; Warfarin | 2007 |
Should EDTA chelation therapy be used instead of long-term clopidogrel plus aspirin to treat patients at risk from drug-eluting stents?
Topics: Angioplasty, Balloon, Coronary; Aspirin; Chelating Agents; Clopidogrel; Drug Implants; Edetic Acid; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stents; Ticlopidine | 2007 |
Optimizing platelet P2Y12 inhibition for patients undergoing PCI.
Topics: Adenosine; Angioplasty, Balloon, Coronary; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Disease; Dose-Response Relationship, Drug; Humans; Membrane Proteins; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Ticagrelor; Ticlopidine | 2007 |
Clinical evidence for anti-inflammatory effects of antiplatelet therapy in patients with atherothrombotic disease.
Topics: Angina, Unstable; Aspirin; Atherosclerosis; Biomarkers; Blood Platelets; Clopidogrel; Humans; Inflammation; Myocardial Infarction; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Stroke; Thrombosis; Ticlopidine | 2007 |
Clopidogrel plus aspirin versus aspirin alone for preventing cardiovascular disease.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine | 2007 |
Perioperative use of anti-platelet drugs.
Topics: Aspirin; Clopidogrel; Coronary Thrombosis; Elective Surgical Procedures; Hemorrhage; Humans; Perioperative Care; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Time Factors; Treatment Outcome | 2007 |
Does clopidogrel rather than aspirin plus a proton-pump inhibitor reduce the frequency of gastrointestinal complications after cardiac surgery?
Topics: Aspirin; Cardiac Surgical Procedures; Clopidogrel; Drug Therapy, Combination; Evidence-Based Medicine; Gastrointestinal Hemorrhage; Humans; Peptic Ulcer; Platelet Aggregation Inhibitors; Postoperative Complications; Proton Pump Inhibitors; Ticlopidine | 2007 |
Pro: continuation of aspirin/clopidogrel for cardiac surgery.
Topics: Aspirin; Cardiac Surgical Procedures; Clopidogrel; Heart Diseases; Humans; Platelet Aggregation Inhibitors; Postoperative Complications; Preoperative Care; Prognosis; Thrombosis; Ticlopidine | 2007 |
Con: continuation of aspirin/clopidogrel for cardiac surgery.
Topics: Aspirin; Cardiac Surgical Procedures; Clopidogrel; Drug Therapy, Combination; Heart Diseases; Humans; Platelet Aggregation Inhibitors; Postoperative Complications; Preoperative Care; Prognosis; Thrombosis; Ticlopidine | 2007 |
Incremental effect of clopidogrel on important outcomes in patients with cardiovascular disease: a meta-analysis of randomized trials.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk Assessment; Stroke; Ticlopidine | 2007 |
Clopidogrel: an updated and comprehensive review.
Topics: Angioplasty, Balloon, Coronary; Animals; Aspirin; Clopidogrel; Drug Approval; Drug Interactions; Humans; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine; United States; United States Food and Drug Administration | 2007 |
Risk reduction with clopidogrel in the management of peripheral arterial disease.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Ticlopidine | 2007 |
Upper GI risks of NSAIDs and antiplatelet agents: key issues for the cardiologist.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Cardiology; Cardiovascular Diseases; Clopidogrel; Dose-Response Relationship, Drug; Fibrinolytic Agents; Gastrointestinal Hemorrhage; Health Care Costs; Helicobacter Infections; Helicobacter pylori; Humans; Patient Selection; Platelet Aggregation Inhibitors; Risk Assessment; Risk Factors; Stomach Ulcer; Ticlopidine | 2005 |
[Management coronary syndrome in the acute phase].
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Thrombosis; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2007 |
[Long-term management of post acute coronary syndrome with oral antiplatelet therapy].
Topics: Acute Coronary Syndrome; Administration, Oral; Aspirin; Clinical Trials as Topic; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Registries; Ticlopidine | 2007 |
[What should be done after the first TIA?].
Topics: Angiotensin-Converting Enzyme Inhibitors; Aspirin; Carotid Artery, Internal; Carotid Stenosis; Clopidogrel; Diuretics; Drug Therapy, Combination; Electrocardiography; Endarterectomy, Carotid; Humans; Indapamide; Ischemic Attack, Transient; Life Style; Middle Aged; Perindopril; Platelet Aggregation Inhibitors; Prognosis; Risk Factors; Stroke; Ticlopidine; Time Factors; Tomography, X-Ray Computed | 2007 |
[Current aspects of secondary prevention of ischemic stroke].
Topics: Aspirin; Cerebral Infarction; Cholesterol, LDL; Clopidogrel; Delayed-Action Preparations; Dipyridamole; Drug Therapy, Combination; Evidence-Based Medicine; Feeding Behavior; Humans; Life Style; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Secondary Prevention; Ticlopidine | 2007 |
Antiplatelet therapy in cerebrovascular disease: implications of Management of Artherothrombosis with Clopidogrel in High-risk Patients and the Clopidogrel for High Artherothrombotic Risk and Ischemic Stabilization, Management, and Avoidance studies' resu
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Embolism, Cholesterol; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Stroke; Ticlopidine | 2007 |
Platelet function testing: state of the art.
Topics: Aspirin; Clopidogrel; Drug Resistance; Flow Cytometry; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2007 |
The PRoFESS trial: future impact on secondary stroke prevention.
Topics: Angiotensin-Converting Enzyme Inhibitors; Aspirin; Benzimidazoles; Benzoates; Brain Ischemia; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Forecasting; Humans; Internationality; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Secondary Prevention; Stroke; Telmisartan; Ticlopidine; Treatment Outcome; Vasodilator Agents | 2007 |
Prevention of secondary stroke and transient ischaemic attack with antiplatelet therapy: the role of the primary care physician [corrected].
Topics: Aged; Aspirin; Clopidogrel; Cost-Benefit Analysis; Dipyridamole; Drug Therapy, Combination; Family Practice; Humans; Ischemic Attack, Transient; Middle Aged; Physician's Role; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Risk Factors; Secondary Prevention; Stroke; Ticlopidine; Treatment Outcome | 2007 |
Antithrombotic therapy and the transition to the catheterization laboratory in UA/NSTEMI.
Topics: Angina, Unstable; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Thrombosis; Drug Therapy, Combination; Electrocardiography; Evidence-Based Medicine; Fibrinolytic Agents; Heparin, Low-Molecular-Weight; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Practice Guidelines as Topic; Ticlopidine; Treatment Outcome | 2007 |
Clopidogrel: who, when, and how?
Topics: Acute Disease; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Hemorrhage; Humans; Myocardial Ischemia; Patient Selection; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Risk Assessment; Secondary Prevention; Syndrome; Ticlopidine; Treatment Outcome | 2007 |
Meta-analysis appraising high clopidogrel loading in patients undergoing percutaneous coronary intervention.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Stenosis; Drug Administration Schedule; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Postoperative Complications; Randomized Controlled Trials as Topic; Ticlopidine | 2007 |
Coronary stents and noncardiac surgery.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Drug-Eluting Stents; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Surgical Procedures, Operative; Thrombosis; Ticlopidine | 2007 |
Management of an acute coronary syndrome in a patient with severe haemophilia A.
Topics: Acute Coronary Syndrome; Antifibrinolytic Agents; Aspirin; Clopidogrel; Fibrinolytic Agents; Hemophilia A; Hemostatics; Heparin; Humans; Life Expectancy; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2007 |
Monitoring of the antiplatelet drugs effect in patients with coronary artery disease: what is the real clinical impact?
Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Drug Monitoring; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine | 2007 |
Platelet function monitoring in patients with coronary artery disease.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Disease; Drug Resistance; Humans; Monitoring, Physiologic; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Risk Factors; Ticlopidine; Treatment Outcome | 2007 |
Low-dose aspirin and clopidogrel: how to act in patients scheduled for day surgery.
Topics: Anesthesia; Aspirin; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Practice Guidelines as Topic; Risk Assessment; Ticlopidine | 2007 |
Clopidogrel and risk for acute coronary events.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Restenosis; Drug Therapy, Combination; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine | 2007 |
Aspirin and clopidogrel resistance.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Clopidogrel; Coronary Thrombosis; Drug Resistance; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Ticlopidine | 2007 |
[Drug-induced thrombotic thrombocytopenic purpura].
Topics: Antirheumatic Agents; Aspirin; Cyclosporine; Diagnosis, Differential; Humans; Immunosuppressive Agents; Penicillamine; Plasma; Plasma Exchange; Platelet Aggregation Inhibitors; Prognosis; Purpura, Thrombotic Thrombocytopenic; Ticlopidine | 2007 |
Monitoring the ACTIVE-W trial: some issues in monitoring a noninferiority trial.
Topics: Administration, Oral; Anticoagulants; Aspirin; Atrial Fibrillation; Biphenyl Compounds; Clinical Trials Data Monitoring Committees; Clopidogrel; Decision Making; Female; Humans; Irbesartan; Male; Prognosis; Randomized Controlled Trials as Topic; Research Design; Risk Assessment; Sensitivity and Specificity; Survival Analysis; Tetrazoles; Ticlopidine; Treatment Outcome | 2008 |
Aspirin combined with clopidogrel (Plavix) decreases cardiovascular events in patients with acute coronary syndrome.
Topics: Acute Coronary Syndrome; Angina, Unstable; Aspirin; Clopidogrel; Coronary Artery Disease; Evidence-Based Medicine; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Thrombosis; Ticlopidine | 2007 |
Increased incidence of in-stent thrombosis related to cocaine use: case series and review of literature.
Topics: Adult; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Cocaine; Cocaine-Related Disorders; Coronary Artery Disease; Coronary Thrombosis; Female; Humans; Incidence; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Stents; Ticlopidine; Treatment Outcome | 2007 |
Antiplatelet therapy for stroke prevention.
Topics: Anticoagulants; Aspirin; Atherosclerosis; Atrial Fibrillation; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2007 |
Antiplatelet agents and randomized trials.
Topics: Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Secondary Prevention; Stroke; Ticlopidine | 2007 |
Antiplatelet therapy with clopidogrel and aspirin in vascular diseases: clinical evidence for and against the combination.
Topics: Aspirin; Cardiovascular Diseases; Cerebrovascular Disorders; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine | 2008 |
[Platelet response to aspirin and clopidogrel. Biochemical evaluation, clinical impact, and pharmacological modulation].
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Resistance; Flow Cytometry; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Thrombosis; Ticlopidine | 2007 |
Current update on glycoprotein IIb-IIIa and direct thrombin inhibition in percutaneous coronary intervention for non-ST elevation acute coronary syndromes: balancing bleeding risk and antiplatelet efficacy.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Antithrombins; Aspirin; Clopidogrel; Enoxaparin; Eptifibatide; Fibrinolytic Agents; Heart Conduction System; Hemorrhage; Heparin; Hirudins; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Peptide Fragments; Peptides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Recombinant Proteins; Risk Assessment; Risk Factors; Ticlopidine | 2008 |
[Drug-eluting stent thrombosis and its pharmacological prevention].
Topics: Aspirin; Clopidogrel; Death, Sudden, Cardiac; Drug-Eluting Stents; Fibrinolytic Agents; Humans; Incidence; Myocardial Infarction; Paclitaxel; Platelet Aggregation Inhibitors; Sirolimus; Terminology as Topic; Thrombosis; Ticlopidine; Turkey | 2007 |
[Monitoring of antiplatelet drug effects--fashion or necessity?].
Topics: Acenocoumarol; Aspirin; Blood Platelets; Clopidogrel; Drug Monitoring; Heparin; Humans; International Normalized Ratio; Partial Thromboplastin Time; Platelet Aggregation Inhibitors; Platelet Function Tests; Prothrombin Time; Ticlopidine | 2008 |
ST-elevation myocardial infarction: the role of adjunctive antiplatelet therapy.
Topics: Abciximab; Antibodies, Monoclonal; Aspirin; Clopidogrel; Electrocardiography; Eptifibatide; Fibrinolytic Agents; Humans; Immunoglobulin Fab Fragments; Myocardial Infarction; Peptides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyridines; Ticlopidine; Tirofiban; Tyrosine | 2008 |
[Antithrombotic therapy after percutanous coronary intervention with stenting].
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Drug-Eluting Stents; Fibrinolytic Agents; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk Factors; Stents; Ticlopidine; Time Factors; Warfarin | 2008 |
[Methods to evaluate aspirin and clopidogrel resistance].
Topics: Aspirin; Clopidogrel; Drug Resistance; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2008 |
Translational therapeutics at the platelet vascular interface. Summary.
Topics: Angina, Unstable; Animals; Aspirin; Blood Platelets; Clopidogrel; Disease Models, Animal; Drug Evaluation, Preclinical; Education, Medical, Continuing; Humans; Mice; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Secondary Prevention; Sensitivity and Specificity; Survival Analysis; Ticlopidine; Treatment Outcome | 2008 |
Indications for dual antiplatelet therapy with aspirin and clopidogrel: evidence-based recommendations for use.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Brain Ischemia; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Drug-Eluting Stents; Evidence-Based Medicine; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2008 |
Individualized antithrombotic therapy in high risk patients after coronary stenting. A double-edged sword between thrombosis and bleeding.
Topics: Algorithms; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Blood Coagulation; Clopidogrel; Drug Resistance; Evidence-Based Medicine; Fibrinolytic Agents; Hemorrhage; Humans; Patient Selection; Perioperative Care; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Risk Assessment; Risk Factors; Stents; Thrombosis; Ticlopidine | 2008 |
[Platelet aggregation inhibition in acute coronary syndrome. Facts and expectations].
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Drug Administration Schedule; Drug Resistance; Drugs, Investigational; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2008 |
Meta-analysis of the efficacy and safety of clopidogrel plus aspirin as compared to antiplatelet monotherapy for the prevention of vascular events.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Humans; Male; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine; Treatment Outcome; Vascular Diseases | 2008 |
Antiplatelet therapy in acute coronary syndromes: the emergency physician's perspective.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Bypass; Dose-Response Relationship, Drug; Emergency Medicine; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine | 2008 |
Role of antiplatelet agents in the primary and secondary prevention of atherothrombotic events in high risk-patients.
Topics: Aspirin; Atherosclerosis; Clinical Trials as Topic; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Ischemia; Platelet Aggregation Inhibitors; Practice Patterns, Physicians'; Thrombosis; Ticlopidine | 2008 |
Use of antiplatelet agents to prevent stroke: what is the role for combinations of medications?
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Drug Interactions; Drug Therapy, Combination; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Risk Assessment; Stroke; Ticlopidine | 2008 |
Antiplatelet drug nonresponsiveness.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Coronary Disease; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2008 |
Interaction effects and subgroup analyses in clinical trials: more than meets the eye?
Topics: Aspirin; Bias; Causality; Clinical Trials as Topic; Clopidogrel; Confounding Factors, Epidemiologic; Data Interpretation, Statistical; Effect Modifier, Epidemiologic; Factor Analysis, Statistical; Humans; Incidence; Linear Models; Platelet Aggregation Inhibitors; Probability; Reproducibility of Results; Research Design; Risk Factors; Thrombosis; Ticlopidine; Treatment Outcome | 2008 |
Guideline on antiplatelet and anticoagulation management in cardiac surgery.
Topics: Anticoagulants; Aprotinin; Aspirin; Cardiac Surgical Procedures; Clopidogrel; Contraindications; Evidence-Based Medicine; Heart Valve Prosthesis Implantation; Hemostasis, Surgical; Hemostatics; Humans; Monitoring, Intraoperative; Perioperative Care; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Ticlopidine; Tranexamic Acid; Warfarin | 2008 |
Antiplatelet therapy for vascular interventions.
Topics: Angioplasty, Balloon; Aspirin; Atherosclerosis; Clopidogrel; Drug Therapy, Combination; Endarterectomy, Carotid; Humans; Inguinal Canal; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Vascular Surgical Procedures | 2008 |
Will prasugrel supersede clopidogrel for acute coronary syndromes?
Topics: Acute Coronary Syndrome; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Coronary Artery Bypass; Hemorrhage; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Randomized Controlled Trials as Topic; Risk Factors; Thiophenes; Ticlopidine | 2008 |
Antiplatelet agents and arterial thrombosis.
Topics: Anticoagulants; Aspirin; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Primary Prevention; Randomized Controlled Trials as Topic; Thrombosis; Ticlopidine; Warfarin | 2008 |
Antithrombotic and thrombolytic therapy for ischemic stroke.
Topics: Aspirin; Benzenesulfonates; Cardiomyopathies; Clopidogrel; Comorbidity; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Neuroprotective Agents; Platelet Aggregation Inhibitors; Primary Prevention; Stroke; Stroke Volume; Thrombolytic Therapy; Ticlopidine | 2008 |
Chronic antithrombotic therapy in post-myocardial infarction patients.
Topics: Anticoagulants; Aspirin; Azetidines; Benzylamines; Clopidogrel; Humans; Myocardial Infarction; Peripheral Vascular Diseases; Platelet Activation; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Recurrence; Risk Factors; Thrombolytic Therapy; Thrombosis; Ticlopidine; Vitamin K; Warfarin | 2008 |
Update on antiplatelet agents, including MATCH, CHARISMA, and ESPRIT.
Topics: Aspirin; Brain Ischemia; Clopidogrel; Coronary Artery Disease; Dipyridamole; Female; Humans; Ischemic Attack, Transient; Male; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine | 2008 |
Antiplatelet therapy in early management of non-ST-segment elevation acute coronary syndrome: the 2002 and 2007 guidelines from North America and Europe.
Topics: Acute Coronary Syndrome; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Contraindications; Europe; Humans; North America; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Practice Guidelines as Topic; Ticlopidine | 2008 |
Aspirin and platelet adenosine diphosphate receptor antagonists in acute coronary syndromes and percutaneous coronary intervention: role in therapy and strategies to overcome resistance.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Ticlopidine; Treatment Outcome | 2008 |
Managing antiplatelet therapy in the ACS patient: straight from the emergency department to you.
Topics: Acute Coronary Syndrome; Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Emergency Treatment; Hospitalists; Humans; Myocardial Revascularization; Platelet Aggregation Inhibitors; Ticlopidine | 2008 |
Review of the 2005 American College of Cardiology, American Heart Association, and Society for Cardiovascular Interventions guidelines for adjunctive pharmacologic therapy during percutaneous coronary interventions: practical implications, new clinical da
Topics: American Heart Association; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Combined Modality Therapy; Coronary Disease; Drug-Eluting Stents; Hirudins; Humans; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Practice Guidelines as Topic; Pyridines; Recombinant Proteins; Societies, Medical; Thrombolytic Therapy; Ticlopidine; United States | 2008 |
Aspirin, clopidogrel, and warfarin: is the combination appropriate and effective or inappropriate and too dangerous?
Topics: Anticoagulants; Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Hemorrhage; Humans; Ischemia; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Ticlopidine; Vascular Diseases; Warfarin | 2008 |
Antiplatelet strategies: evaluating their current role in the setting of acute coronary syndromes.
Topics: Abciximab; Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Blood Platelets; Clopidogrel; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Humans; Immunoglobulin Fab Fragments; Myocardial Infarction; Patient Selection; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Risk Assessment; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2008 |
Investigating the mechanisms of hyporesponse to antiplatelet approaches.
Topics: Aspirin; Blood Platelets; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Genetic Predisposition to Disease; Humans; Patient Selection; Platelet Aggregation Inhibitors; Platelet Function Tests; Risk Assessment; Risk Factors; Ticlopidine; Treatment Outcome | 2008 |
Safety of clopidogrel and aspirin for stroke prevention: implications of the CHARISMA trial.
Topics: Animals; Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2008 |
Interpreting the CHARISMA study. What is the role of dual antiplatelet therapy with clopidogrel and aspirin?
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Thromboembolism; Ticlopidine | 2008 |
Antiplatelet and anticoagulant agents: key differences in mechanisms of action, clinical application, and therapeutic benefit in patients with non-ST-segment-elevation acute coronary syndromes.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Hirudins; Humans; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Recombinant Proteins; Ticlopidine | 2008 |
Clopidogrel in secondary ischemic stroke prevention.
Topics: Aspirin; Brain Ischemia; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Patient Selection; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Risk Assessment; Risk Factors; Secondary Prevention; Stroke; Thrombolytic Therapy; Ticlopidine; Treatment Outcome | 2008 |
Dual antiplatelet therapy with clopidogrel and aspirin.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Contraindications; Coronary Artery Bypass; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Polypharmacy; Ticlopidine | 2008 |
Antithrombotic therapy in patients treated with oral anticoagulation undergoing coronary artery stenting. An expert consensus document with focus on atrial fibrillation.
Topics: Administration, Oral; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Drug Therapy, Combination; Humans; Myocardial Revascularization; Postoperative Care; Stents; Thrombosis; Ticlopidine; Warfarin | 2008 |
Antiplatelet treatment of cardiovascular disease: a translational research perspective.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Coronary Thrombosis; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Ticlopidine | 2008 |
Coronary artery stents: II. Perioperative considerations and management.
Topics: Anesthesia, Conduction; Angioplasty, Balloon, Coronary; Aspirin; Blood Loss, Surgical; Clopidogrel; Coronary Restenosis; Coronary Thrombosis; Coronary Vessels; Humans; Perioperative Care; Platelet Aggregation Inhibitors; Stents; Surgical Procedures, Operative; Ticlopidine | 2008 |
Current antiplatelet therapies: benefits and limitations.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine | 2008 |
Oral antiplatelet agents and bleeding risk in relation to major cardiovascular surgery.
Topics: Aspirin; Cardiovascular Surgical Procedures; Cilostazol; Clopidogrel; Dipyridamole; Humans; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Risk; Tetrazoles; Ticlopidine | 2006 |
Acetylsalicylic acid + extended-release dipyridamole combination therapy for secondary stroke prevention.
Topics: Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Secondary Prevention; Stroke; Ticlopidine | 2008 |
Treatment strategies in non-ST-elevation acute coronary syndromes in patients undergoing percutaneous coronary intervention: an evidence-based review of clinical trial results and treatment guidelines: report on a roundtable discussion.
Topics: Acute Coronary Syndrome; Algorithms; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Cardiovascular Agents; Clinical Trials as Topic; Clopidogrel; Emergency Treatment; Evidence-Based Medicine; Fibrinolytic Agents; Hirudins; Humans; Peptide Fragments; Piperazines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Postoperative Hemorrhage; Practice Guidelines as Topic; Prasugrel Hydrochloride; Recombinant Proteins; Risk Assessment; Stents; Thiophenes; Thrombosis; Ticlopidine | 2008 |
Clinical implications of aspirin resistance.
Topics: Aspirin; Atherosclerosis; Clinical Trials as Topic; Clopidogrel; Coronary Disease; Drug Resistance; Humans; Ischemia; Research Design; Stroke; Thrombosis; Ticlopidine; Treatment Outcome | 2008 |
The approach to optimizing stroke care.
Topics: Aspirin; Clopidogrel; Delayed-Action Preparations; Dipyridamole; Drug Therapy, Combination; Emergency Service, Hospital; Fibrinolytic Agents; Guidelines as Topic; Humans; Platelet Aggregation Inhibitors; Secondary Prevention; Stroke; Ticlopidine | 2008 |
Reducing the risk of adverse thrombotic events - The role of aspirin and clopidogrel.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine | 2008 |
Combination antiplatelet agents for secondary prevention of ischemic stroke.
Topics: Aspirin; Brain Ischemia; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2008 |
Clopidogrel and aspirin in cardiovascular medicine: responders or not--current best available evidence.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2008 |
Drug-eluting stents and antiplatelet resistance.
Topics: Aspirin; Clopidogrel; Drug Resistance; Drug-Eluting Stents; Humans; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine | 2008 |
Intensity of antiplatelet therapy in patients with acute coronary syndromes and percutaneous coronary intervention: the promise of prasugrel?
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Thrombosis; Ticlopidine | 2008 |
Aspirin and clopidogrel response variability: review of the published literature.
Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Drug Interactions; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Secondary Prevention; Ticlopidine | 2008 |
Platelet ADP-receptor antagonists for cardiovascular disease: past, present and future.
Topics: Adenosine; Adenosine Monophosphate; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; History, 20th Century; History, 21st Century; Humans; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Stents; Thiophenes; Ticagrelor; Ticlopidine; Treatment Outcome | 2008 |
Digestion of the antiplatelets comparison of PRoFESS: 18-7=1?
Topics: Aged; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stroke; Ticlopidine; Treatment Outcome | 2009 |
Diabetes, vascular complications and antiplatelet therapy: open problems.
Topics: Aspirin; Clopidogrel; Diabetes Mellitus; Diabetic Angiopathies; Drug Interactions; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2009 |
[Current issues of anticoagulation therapy in the course of dental treatment and oral surgery].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Aspirin, Dipyridamole Drug Combination; Clopidogrel; Dental Care; Dipyridamole; Drug Administration Schedule; Drug Combinations; Humans; Oral Surgical Procedures; Platelet Aggregation Inhibitors; Ticlopidine | 2008 |
The genetics of antiplatelet drug resistance.
Topics: Aspirin; Blood Platelets; Clopidogrel; Humans; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Thrombosis; Ticlopidine | 2009 |
Antiplatelet drug response variability and the role of platelet function testing: a practical guide for interventional cardiologists.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Myocardial Ischemia; Patient Compliance; Patient Selection; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Practice Guidelines as Topic; Predictive Value of Tests; Recurrence; Risk Assessment; Stents; Ticlopidine; Treatment Failure; Treatment Outcome | 2009 |
The rationale for and comparisons of different antiplatelet treatments in acute coronary syndrome.
Topics: Acute Coronary Syndrome; Aspirin; Blood Coagulation; Blood Platelets; Clopidogrel; Drug Therapy, Combination; Eptifibatide; Humans; Ischemia; Peptides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Randomized Controlled Trials as Topic; Risk Factors; Ticlopidine; Treatment Outcome | 2008 |
Multifunctional actions of approved and candidate stroke drugs.
Topics: Albumins; Animals; Antihypertensive Agents; Aspirin; Brain Ischemia; Clopidogrel; Cytidine Diphosphate Choline; Dipyridamole; Erythropoietin; Granulocyte Colony-Stimulating Factor; Humans; Hypolipidemic Agents; Neuroprotective Agents; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2009 |
[Variable platelet response to aspirin and new therapeutic targets].
Topics: Aspirin; Blood Platelets; Clopidogrel; Drug Resistance; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2009 |
[Resistance to platelet antiaggregants: the cardiologist's point of view].
Topics: Aspirin; Cardiology; Clopidogrel; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2009 |
Prasugrel development - claims and achievements.
Topics: Administration, Oral; Angioplasty, Balloon, Coronary; Animals; Aspirin; Blood Platelets; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Drug Administration Schedule; Drug Discovery; Drug Resistance; Hemorrhage; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Research Design; Risk Assessment; Stents; Thiophenes; Ticlopidine; Treatment Outcome | 2009 |
What's new in stroke? The top 10 studies of 2006-2008. Part I.
Topics: Aspirin; Brain Ischemia; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Evidence-Based Medicine; Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Ticlopidine; Treatment Outcome | 2008 |
Role of antiplatelet therapy across the spectrum of patients with coronary artery disease.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome | 2009 |
Variability in responsiveness to oral antiplatelet therapy.
Topics: Acute Coronary Syndrome; Administration, Oral; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Signal Transduction; Ticlopidine; Treatment Outcome | 2009 |
Monitoring platelet function to reduce the risk of ischemic and bleeding complications.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Clopidogrel; Hemorrhage; Humans; Ischemia; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Risk Factors; Sensitivity and Specificity; Ticlopidine; Treatment Outcome | 2009 |
[Risk of gastrointestinal bleeding with aspirin and platelet antiaggregants].
Topics: Age Factors; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Clopidogrel; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dinoprostone; Gastrointestinal Hemorrhage; Helicobacter Infections; Helicobacter pylori; Histamine H2 Antagonists; Humans; Middle Aged; Misoprostol; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Risk Factors; Thromboxanes; Ticlopidine | 2009 |
Interindividual variability in the response to oral antiplatelet drugs: a position paper of the Working Group on antiplatelet drugs resistance appointed by the Section of Cardiovascular Interventions of the Polish Cardiac Society, endorsed by the Working
Topics: Aspirin; Clopidogrel; Coronary Disease; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Monitoring; Drug Resistance; Female; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine | 2009 |
Optimizing long-term dual aspirin/clopidogrel therapy in acute coronary syndromes: when does the risk outweigh the benefit?
Topics: Acute Coronary Syndrome; Administration, Oral; Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Humans; Outcome Assessment, Health Care; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Ticlopidine | 2009 |
Antiplatelet therapy after endovascular intervention: does combination therapy really work and what is the optimum duration of therapy?
Topics: Angioplasty, Balloon, Coronary; Aspirin; Blood Vessel Prosthesis Implantation; Cardiovascular Diseases; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Evidence-Based Medicine; Graft Occlusion, Vascular; Humans; Myocardial Infarction; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome; Vascular Patency | 2009 |
Combination antiplatelet therapy in patients with peripheral arterial disease: is the best therapy aspirin, clopidogrel, or both?
Topics: Aspirin; Atherosclerosis; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Evidence-Based Medicine; Hemodynamics; Hemorrhage; Humans; Ischemia; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Risk Assessment; Thrombosis; Ticlopidine; Treatment Outcome | 2009 |
[Resistance to desaggregants: causes, clinical implication, methods of diagnosis and correction].
Topics: Aspirin; Clopidogrel; Coronary Thrombosis; Dose-Response Relationship, Drug; Drug Resistance; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Myocardial Ischemia; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2008 |
Antiplatelet agents for prevention of recurrent ischemic stroke.
Topics: Aspirin; Brain Ischemia; Clopidogrel; Dipyridamole; Humans; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Stroke; Ticlopidine | 2009 |
[Routine platelet aggregation inhibition not useful when using acetylsalicylic acid or clopidogrel].
Topics: Aspirin; Clopidogrel; Drug Resistance; Humans; Mass Screening; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Ticlopidine; Treatment Failure | 2009 |
Variability in platelet response to the antiplatelet agents aspirin and clopidogrel: mechanisms, measurement, and clinical relevance.
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Probability; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Ticlopidine; Treatment Outcome | 2009 |
Antiplatelet therapy and coronary artery bypass graft surgery: perioperative safety and efficacy.
Topics: Aspirin; Clopidogrel; Coronary Artery Bypass; Drug Administration Schedule; Drug Therapy, Combination; Humans; Meta-Analysis as Topic; Perioperative Care; Platelet Aggregation Inhibitors; Postoperative Complications; Postoperative Period; Randomized Controlled Trials as Topic; Risk Assessment; Ticlopidine | 2009 |
Does timing matter? Upstream or downstream administration of antiplatelet therapy.
Topics: Acute Coronary Syndrome; Algorithms; Aspirin; Clopidogrel; Coronary Angiography; Drug Administration Schedule; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Risk Assessment; Risk Factors; Ticlopidine | 2009 |
Antiplatelet therapy in diabetes: efficacy and limitations of current treatment strategies and future directions.
Topics: Aspirin; Clopidogrel; Diabetes Mellitus; Diabetic Angiopathies; Drug Resistance; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Secondary Prevention; Ticlopidine | 2009 |
Response variability and the role of platelet function testing.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Clopidogrel; Humans; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Thiophenes; Ticlopidine | 2009 |
Antiplatelet drugs for ischemic stroke prevention.
Topics: Aged; Anticoagulants; Aspirin; Brain Ischemia; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Patient Selection; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Primary Prevention; Risk Assessment; Secondary Prevention; Stroke; Ticlopidine; Treatment Outcome | 2009 |
Antiplatelet drug 'resistance'. Part 1: mechanisms and clinical measurements.
Topics: Animals; Aspirin; Blood Platelets; Clopidogrel; Drug Interactions; Drug Resistance; Drug Therapy, Combination; Humans; Medication Adherence; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Genetic; Predictive Value of Tests; Ticlopidine; Treatment Failure | 2009 |
Percutaneous coronary intervention: assessing coronary vascular risk associated with bare-metal and drug-eluting stents.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Risk Factors; Stents; Ticlopidine | 2009 |
Acute coronary syndrome and its antithrombotic treatment: focus on aspirin and clopidogrel resistance.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Resistance; Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine | 2009 |
Combination antiplatelet therapy for secondary stroke prevention: enhanced efficacy or double trouble?
Topics: Anticoagulants; Aspirin; Aspirin, Dipyridamole Drug Combination; Clopidogrel; Dipyridamole; Drug Combinations; Drug Therapy, Combination; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Treatment Outcome | 2009 |
Significant gastrointestinal bleeding in patients at risk of coronary stent thrombosis.
Topics: Aged, 80 and over; Angioplasty, Balloon, Coronary; Anti-Bacterial Agents; Aspirin; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Duodenal Ulcer; Endoscopy, Gastrointestinal; Female; Helicobacter Infections; Helicobacter pylori; Humans; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Proton Pump Inhibitors; Risk Assessment; Risk Factors; Thrombosis; Ticlopidine; Treatment Outcome | 2009 |
Antiplatelet therapy in ischemic stroke: variability in clinical trials and its impact on choosing the appropriate therapy.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Atherosclerosis; Brain Ischemia; Clinical Trials as Topic; Clopidogrel; Confounding Factors, Epidemiologic; Decision Making; Dipyridamole; Double-Blind Method; Drug Therapy, Combination; Evidence-Based Medicine; Female; Follow-Up Studies; Hemorrhage; Humans; Ischemic Attack, Transient; Male; Middle Aged; Multicenter Studies as Topic; Patient Selection; Platelet Aggregation Inhibitors; Research Design; Secondary Prevention; Ticlopidine | 2009 |
New antiplatelet drugs: beyond aspirin and clopidogrel.
Topics: Adenosine; Adenosine Monophosphate; Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Drug Design; Humans; Imines; Lactones; Naphthalenes; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Propionates; Purinergic P2 Receptor Antagonists; Pyridines; Thiophenes; Ticagrelor; Ticlopidine | 2009 |
Possibility of a rebound phenomenon following antiplatelet therapy withdrawal: a look at the clinical and pharmacological evidence.
Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Risk Factors; Ticlopidine; Withholding Treatment | 2009 |
Diabetes mellitus: a prothrombotic state implications for outcomes after coronary revascularization.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Agents; Clopidogrel; Coronary Angiography; Coronary Stenosis; Coronary Thrombosis; Diabetes Mellitus, Type 2; Drug-Eluting Stents; Female; Humans; Medication Adherence; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk Factors; Sirolimus; Ticlopidine; Treatment Outcome | 2009 |
[New approach to interventional cardiology treatment with personalized medicine].
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Clopidogrel; Drug Resistance; Hematologic Diseases; Humans; Myocardial Infarction; Personal Health Services; Ticlopidine; Treatment Failure | 2008 |
Management of patients with high gastrointestinal risk on antiplatelet therapy.
Topics: Aspirin; Clopidogrel; Gastrointestinal Hemorrhage; Humans; Peptic Ulcer; Peptic Ulcer Hemorrhage; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Proton Pump Inhibitors; Risk Factors; Thiophenes; Ticlopidine | 2009 |
Prasugrel: newest antiplatelet agent and its emerging role in management of acute coronary syndrome and percutaneous coronary intervention.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Resistance; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Pyridines; Thiophenes; Ticlopidine | 2009 |
Bedside evaluation of thienopyridine antiplatelet therapy.
Topics: Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Aspirin; Clinical Trials as Topic; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Resistance; Drug Therapy, Combination; Humans; Mass Screening; Myocardial Infarction; Nephelometry and Turbidimetry; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Point-of-Care Systems; Prasugrel Hydrochloride; Prodrugs; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Thiophenes; Thrombelastography; Ticlopidine; United States | 2009 |
[Drug-eluting stents: implications for modern coronary revascularization].
Topics: Angioplasty, Balloon, Coronary; Aspirin; Bias; Clopidogrel; Comorbidity; Coronary Artery Bypass; Coronary Restenosis; Drug Therapy, Combination; Drug-Eluting Stents; Guideline Adherence; Hemorrhage; Humans; Intraoperative Complications; Long-Term Care; Platelet Aggregation Inhibitors; Publication Bias; Reoperation; Substance Withdrawal Syndrome; Survival Rate; Ticlopidine; Treatment Outcome | 2009 |
Peri-procedural platelet function and platelet inhibition in percutaneous coronary intervention.
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Resistance; Hemorrhage; Humans; Myocardial Infarction; Platelet Activation; Platelet Aggregation Inhibitors; Risk Assessment; Risk Factors; Thrombin; Ticlopidine; Treatment Outcome | 2008 |
P2X(1) receptor inhibition and soluble CD39 administration as novel approaches to widen the cardiovascular therapeutic window.
Topics: Adenosine Triphosphate; Antigens, CD; Apyrase; Aspirin; Biomedical Research; Cardiovascular Diseases; Cerebral Hemorrhage; Clinical Trials as Topic; Clopidogrel; Cyclooxygenase Inhibitors; Drug Therapy, Combination; Endothelium, Vascular; Humans; Myocardial Ischemia; Platelet Aggregation Inhibitors; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2Y12; Ticlopidine; Treatment Outcome | 2009 |
Antiplatelet therapy in percutaneous coronary intervention: a critical review of the 2007 AHA/ACC/SCAI guidelines and beyond.
Topics: American Heart Association; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Evidence-Based Medicine; Humans; Medication Adherence; Metals; Patient Selection; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Practice Guidelines as Topic; Prosthesis Design; Risk Assessment; Stents; Ticlopidine; Treatment Outcome; United States | 2009 |
Improving outcomes in patients undergoing percutaneous coronary intervention: role of prasugrel.
Topics: Administration, Oral; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Thrombosis; Diabetes Complications; Drug Resistance; Drug Therapy, Combination; Humans; Myocardial Infarction; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Risk Assessment; Risk Factors; Stents; Thiophenes; Ticlopidine; Treatment Outcome | 2009 |
Hospitals with and without percutaneous coronary intervention capability: considerations for treating acute coronary syndromes.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Emergency Service, Hospital; Enoxaparin; Fondaparinux; Health Services Accessibility; Hirudins; Humans; Peptide Fragments; Platelet Aggregation Inhibitors; Polysaccharides; Recombinant Proteins; Ticlopidine; Triage; United States | 2009 |
Aggressive chronic platelet inhibition with prasugrel and increased cancer risks: revising oral antiplatelet regimens?
Topics: Animals; Aspirin; Clopidogrel; Colonic Neoplasms; Gastrointestinal Hemorrhage; Humans; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Randomized Controlled Trials as Topic; Thiophenes; Ticlopidine | 2009 |
A new generation of antiplatelet agents.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Pyridines; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Receptors, Thrombin; Ticlopidine; von Willebrand Factor | 2009 |
Platelet resistance to antiplatelet drugs.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Resistance, Multiple; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2009 |
Diabetes and acute coronary syndromes.
Topics: Acute Coronary Syndrome; Anticoagulants; Aspirin; Blood Glucose; Clopidogrel; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Enoxaparin; Hirudins; Humans; Hypoglycemic Agents; Peptide Fragments; Piperazines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prasugrel Hydrochloride; Randomized Controlled Trials as Topic; Recombinant Proteins; Thiophenes; Thrombosis; Ticlopidine | 2009 |
Aspirin and clopidogrel: efficacy and resistance in diabetes mellitus.
Topics: Aspirin; Clopidogrel; Diabetes Mellitus; Drug Resistance; Endothelium, Vascular; Humans; Ischemia; Oxidative Stress; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine | 2009 |
[Clopidogrel resistance].
Topics: Aspirin; Clopidogrel; Coronary Thrombosis; Drug Resistance; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2009 |
Antithrombotic therapies in cerebrovascular disease: what should we use as secondary prevention in patients with carotid artery disease?
Topics: Anticoagulants; Aspirin; Brain Ischemia; Carotid Stenosis; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Female; Fibrinolytic Agents; Humans; Male; Patient Selection; Risk Assessment; Secondary Prevention; Stroke; Ticlopidine; Treatment Outcome | 2009 |
Evidence for using clopidogrel alone or in addition to aspirin in post coronary artery bypass surgery patients.
Topics: Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Restenosis; Drug Therapy, Combination; Electrocardiography; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Postoperative Care; Ticlopidine; Treatment Outcome | 2009 |
Safety and tolerability of antiplatelet therapies for the secondary prevention of atherothrombotic disease.
Topics: Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Secondary Prevention; Ticlopidine | 2009 |
[Technological and biopharmaceutical aspects. Antiplatelet agents for oral administration].
Topics: Administration, Oral; Animals; Aspirin; Clopidogrel; Dipyridamole; Humans; Patents as Topic; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Ticlopidine | 2009 |
[Diagnosis, causes, relevance of a complex phenomenon. Resistance to aspirin and clopidogrel].
Topics: Aspirin; Blood Platelets; Clopidogrel; Drug Interactions; Drug Resistance; Humans; Phosphorylation; Platelet Aggregation Inhibitors; Platelet Function Tests; Thrombosis; Thromboxanes; Ticlopidine | 2009 |
The effect of different treatment durations of clopidogrel in patients with non-ST-segment elevation acute coronary syndromes: a systematic review and value of information analysis.
Topics: Acute Coronary Syndrome; Adolescent; Adult; Aged; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine; Time Factors; Treatment Outcome; United Kingdom; Withholding Treatment; Young Adult | 2009 |
Assessment, mechanisms, and clinical implication of variability in platelet response to aspirin and clopidogrel therapy.
Topics: Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Prognosis; Ticlopidine | 2009 |
[Study of variability in response to aspirin and clopidogrel: clinical and/or biological resistance?].
Topics: Animals; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Drug Resistance; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2009 |
Antiplatelet therapy discontinuation following drug-eluting stent placement: dangers, reasons, and management recommendations.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Health Knowledge, Attitudes, Practice; Hemorrhage; Humans; Medication Adherence; Oral Surgical Procedures; Patient Education as Topic; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Practice Guidelines as Topic; Risk Assessment; Risk Factors; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2009 |
The present state of aspirin and clopidogrel resistance.
Topics: Anti-Inflammatory Agents; Aspirin; Clopidogrel; Coronary Disease; Drug Monitoring; Humans; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine | 2009 |
Coronary stent thrombosis in patients with chronic renal insufficiency.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Thrombosis; Drug-Eluting Stents; Humans; Platelet Glycoprotein GPIIb-IIIa Complex; Renal Insufficiency, Chronic; Risk Factors; Stents; Ticlopidine | 2010 |
Challenges in oral antiplatelet therapy: ST-segment elevation myocardial infarction.
Topics: Administration, Oral; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Administration Schedule; Humans; Myocardial Infarction; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Ticlopidine | 2009 |
Platelet-directed therapies and coronary artery bypass grafting.
Topics: Aspirin; Clopidogrel; Coronary Artery Bypass; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine | 2009 |
Nonsteroid anti-inflammatory drug-induced gastroduodenal injury.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Cyclooxygenase Inhibitors; Drug Interactions; Duodenal Diseases; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Risk Assessment; Stomach Diseases; Ticlopidine | 2009 |
Effect of pharmaceutical interventions targeting thromboxane receptors and thromboxane synthase in cardiovascular and renal diseases.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Humans; Kidney Diseases; Platelet Aggregation Inhibitors; Proteinuria; Receptors, Thrombin; Thrombosis; Thromboxane A2; Thromboxane-A Synthase; Ticlopidine | 2009 |
Platelet function testing and implications for clinical practice.
Topics: Aspirin; Blood Platelets; Clopidogrel; Drug Resistance; Hemorrhage; Hemostasis; Humans; Ischemia; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Predictive Value of Tests; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Risk Assessment; Thrombosis; Ticlopidine; Treatment Outcome | 2009 |
Antiplatelet resistance--fact or myth?
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Resistance; Humans; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Risk Factors; Stents; Thrombosis; Ticlopidine | 2009 |
Dental management of patients taking antiplatelet medications.
Topics: Aspirin; Clopidogrel; Cyclooxygenase Inhibitors; Dental Care for Chronically Ill; Humans; Oral Hemorrhage; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Thrombosis; Ticlopidine | 2009 |
Thienopyridine derivatives versus aspirin for preventing stroke and other serious vascular events in high vascular risk patients.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stroke; Ticlopidine | 2009 |
[Perioperative antiplatelet therapy of patients with coronary stents].
Topics: Administration, Oral; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Cohort Studies; Coronary Disease; Humans; Meta-Analysis as Topic; Platelet Aggregation Inhibitors; Postoperative Complications; Practice Guidelines as Topic; Retrospective Studies; Risk Factors; Stents; Thrombosis; Ticlopidine; Time Factors | 2009 |
Antiplatelet treatment in ischemic stroke treatment.
Topics: Aspirin; Brain Ischemia; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2009 |
Clopidogrel: mechanisms of action and review of the evidence relating to use during skin surgery procedures.
Topics: Aspirin; Blood Loss, Surgical; Clopidogrel; Dermatologic Surgical Procedures; Drug Therapy, Combination; Humans; Perioperative Care; Platelet Aggregation; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Ticlopidine | 2010 |
Optimizing antiplatelet therapy in high-risk patients with atrial fibrillation: insights from Atrial Fibrillation Clopidogrel Trial with Irbesartan for Prevention of Vascular Events (ACTIVE A).
Topics: Antihypertensive Agents; Aspirin; Atrial Fibrillation; Biphenyl Compounds; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Contraindications; Humans; Irbesartan; Platelet Aggregation Inhibitors; Risk Assessment; Risk Factors; Tetrazoles; Ticlopidine; Treatment Outcome | 2009 |
[Long-term use of oral antiplatelet therapy: from studies to practice].
Topics: Administration, Oral; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Combinations; Fibrinolytic Agents; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Assessment; Ticlopidine | 2010 |
Dual antiplatelet therapy in coronary artery disease: a case-based approach.
Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Myocardial Infarction; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Stents; Thiophenes; Ticlopidine | 2009 |
[Prevention of GI bleeding due to antiplatelet agents: a labyrinth!].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aspirin; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Lansoprazole; Omeprazole; Pantoprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Ticlopidine | 2009 |
Impact of genetic and acquired alteration in cytochrome P450 system on pharmacologic and clinical response to clopidogrel.
Topics: Aspirin; Calcium Channel Blockers; Clopidogrel; Cytochrome P-450 Enzyme System; Drug Interactions; Drug Resistance; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Polypharmacy; Proton Pump Inhibitors; Ticlopidine | 2010 |
Variable platelet responsiveness to aspirin and clopidogrel: role of platelet function and genetic polymorphism testing.
Topics: Aspirin; Blood Platelets; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Ticlopidine | 2009 |
Gastrointestinal bleed with clopidogrel and aspirin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2010 |
Replacing aspirin and warfarin for secondary stroke prevention: is it worth the costs?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Benzimidazoles; Clopidogrel; Cost-Benefit Analysis; Dabigatran; Humans; Platelet Aggregation Inhibitors; Pyridines; Stroke; Ticlopidine; Warfarin | 2010 |
Antiplatelets and stroke outcomes: state of the science.
Topics: Arachidonic Acid; Aspirin; Aspirin, Dipyridamole Drug Combination; Brain Ischemia; Clopidogrel; Dipyridamole; Drug Combinations; Evidence-Based Practice; Humans; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Risk Factors; Risk Reduction Behavior; Safety; Secondary Prevention; Stroke; Ticlopidine; Treatment Outcome | 2009 |
Aspirin and clopidogrel hyporesponsiveness and nonresponsiveness in patients with coronary artery stenting.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Recurrence; Risk Assessment; Risk Factors; Stents; Thrombosis; Ticlopidine; Treatment Outcome | 2009 |
Antiplatelet agents.
Topics: Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Resistance; Drug Therapy, Combination; Forecasting; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Practice Guidelines as Topic; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Ticlopidine | 2009 |
[Medicinal therapy for interventional surgery of the peripheral vascular system].
Topics: Administration, Oral; Anticoagulants; Arterial Occlusive Diseases; Aspirin; Clopidogrel; Drug Therapy, Combination; Heparin; Humans; Infusions, Intravenous; Ischemia; Leg; Long-Term Care; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Secondary Prevention; Thrombocytopenia; Thrombosis; Ticlopidine; Vitamin K | 2010 |
Current standings of the proton pump inhibitor and clopidogrel co-therapy: review on an evolving field with the eyes of the gastroenterologist.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Gastroenterology; Gastrointestinal Hemorrhage; Humans; Myocardial Infarction; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Recurrence; Ticlopidine | 2010 |
A guide to anticoagulation and endocarditis prophylaxis during cutaneous surgery.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibiotic Prophylaxis; Anticoagulants; Aspirin; Calcium Channel Blockers; Clopidogrel; Dipyridamole; Endocarditis, Bacterial; Humans; International Normalized Ratio; Perioperative Care; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Risk Factors; Skin Diseases; Ticlopidine; Warfarin | 2010 |
[Thienopyridines in the treatment and prevention of cardiovascular diseases. III. therapeutic application of clopidogrel as monotherapy (without acetylsalicylic acid)].
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Pyridines; Randomized Controlled Trials as Topic; Receptors, Purinergic P2Y12; Ticlopidine; Ulcer | 2009 |
[Thienopyridines in the treatment and prevention of cardiovascular diseases. Part IV. therapeutic application of clopidogrel in combination with acetylsalicylic acid in acute coronary syndromes and percutaneous coronary interventions].
Topics: Acute Coronary Syndrome; American Heart Association; Angioplasty, Balloon; Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Thrombosis; Ticlopidine; United States | 2009 |
Unresolved issues associated with early initiation of antiplatelet therapy in acute coronary syndromes.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine; Time Factors | 2010 |
Acute myocardial infarction in a patient with post-splenectomy thrombocytosis: a case report and review of literature.
Topics: Adult; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Follow-Up Studies; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Count; Radiography; Smoking; Splenectomy; Stents; Thrombocytosis; Ticlopidine; Treatment Outcome | 2010 |
Combination antithrombotic therapies.
Topics: Aspirin; Atherosclerosis; Clopidogrel; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Pyridines; Thrombosis; Ticlopidine | 2010 |
Antithrombotic and fibrinolytic drugs for retinal vein occlusion: a systematic review and a call for action.
Topics: Aspirin; Drug Evaluation; Fibrinolytic Agents; Heparin, Low-Molecular-Weight; Humans; Randomized Controlled Trials as Topic; Retinal Vein Occlusion; Ticlopidine; Treatment Outcome; Visual Acuity; Warfarin | 2010 |
Platelet pharmacogenomics.
Topics: Aspirin; Blood Platelets; Clopidogrel; Cohort Studies; Genomics; Humans; Pharmacogenetics; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine | 2010 |
Drug interaction between clopidogrel and proton pump inhibitors.
Topics: Aspirin; Biomarkers; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Heart; Humans; Metabolic Detoxication, Phase I; Platelet Aggregation Inhibitors; Prodrugs; Proton Pump Inhibitors; Ticlopidine | 2010 |
Neuraxial anesthesia in obstetric patients receiving anticoagulant and antithrombotic drugs.
Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Anticoagulants; Aspirin; Clopidogrel; Female; Fibrinolytic Agents; Fondaparinux; Guidelines as Topic; Hematoma, Epidural, Spinal; Heparin; Hirudins; Humans; Polysaccharides; Pregnancy; Ticlopidine; Warfarin | 2010 |
Current guidelines on antiplatelet agents for secondary prevention of noncardiogenic stroke: an evidence-based review.
Topics: American Heart Association; Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Risk Factors; Secondary Prevention; Stroke; Ticlopidine; United States; Vasodilator Agents | 2010 |
Preventing serious sequelae after an acute coronary syndrome: the consequences of thrombosis versus bleeding with antiplatelet therapy.
Topics: Acute Coronary Syndrome; Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Artery Bypass; Hemorrhage; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Pyridines; Risk Factors; Thiophenes; Thrombosis; Ticlopidine | 2010 |
Antiplatelet and antithrombotic treatment of patients with peripheral arterial disease.
Topics: Administration, Oral; Aspirin; Cardiovascular Diseases; Clopidogrel; Disease Progression; Dose-Response Relationship, Drug; Drug Resistance; Drug Therapy, Combination; Fibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Risk Assessment; Ticlopidine; Treatment Outcome | 2010 |
Aspirin and clopidogrel resistance: should we worry about?
Topics: Aspirin; Clopidogrel; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Thromboembolism; Ticlopidine | 2010 |
Platelet function tests and resistance to antiplatelet therapy.
Topics: Aspirin; Clopidogrel; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2010 |
Antiplatelet therapy prasugrel: a novel platelet ADP P2Y12 receptor antagonist.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Clinical Trials, Phase III as Topic; Clopidogrel; Drug Evaluation, Preclinical; Drug Therapy, Combination; Hemorrhage; Humans; Ischemia; Kidney Failure, Chronic; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Randomized Controlled Trials as Topic; Receptors, Purinergic P2Y12; Thiophenes; Ticlopidine | 2010 |
Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. BET 1: Adding clopidogrel to standard treatment for acute myocardial infarction.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Emergency Service, Hospital; Evidence-Based Emergency Medicine; Fibrinolytic Agents; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine | 2010 |
Heterogeneity of efficacy and safety of antiplatelet therapy in cardiovascular and cerebrovascular disease.
Topics: Acute Coronary Syndrome; Aspirin; Cardiovascular Diseases; Cerebrovascular Disorders; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Humans; Platelet Aggregation Inhibitors; Secondary Prevention; Ticlopidine | 2010 |
Prolonged infusion of eptifibatide as bridge therapy between bare-metal stent insertion and cardiovascular surgery: case report and review of the literature.
Topics: Angioplasty; Anticoagulants; Aspirin; Cardiovascular Surgical Procedures; Clopidogrel; Coronary Artery Bypass; Eptifibatide; Hemorrhage; Humans; Male; Metals; Middle Aged; Peptides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Stents; Thrombosis; Ticlopidine | 2010 |
The role of antiplatelet therapy in the secondary prevention of coronary artery disease.
Topics: Adenosine; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Interactions; Drug Therapy, Combination; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Risk Factors; Secondary Prevention; Thiophenes; Thromboxane A2; Ticagrelor; Ticlopidine | 2010 |
Diabetes and the platelet: toward new therapeutic paradigms for diabetic atherothrombosis.
Topics: Acute Coronary Syndrome; Apoptosis; Aspirin; Blood Platelets; Clopidogrel; Diabetes Complications; Diabetes Mellitus; Glycoproteins; Humans; Models, Biological; Piperazines; Platelet Activation; Prasugrel Hydrochloride; Receptors, Purinergic P2Y12; Thiophenes; Thromboplastin; Thrombosis; Ticlopidine | 2010 |
[Discontinuation of treatment with platelet aggregation inhibitors in surgical patients with cardiac stents].
Topics: Angioplasty, Balloon, Coronary; Aspirin; Blood Loss, Surgical; Clopidogrel; Coronary Thrombosis; Drug Administration Schedule; Drug Therapy, Combination; Elective Surgical Procedures; Emergencies; Evidence-Based Medicine; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Practice Guidelines as Topic; Risk Assessment; Stents; Ticlopidine; Time Factors | 2010 |
Economy class syndrome complicated by stroke: a rare condition due to paradoxical embolism--a case report and review of the literature.
Topics: Aircraft; Anticoagulants; Aspirin; Clopidogrel; Echocardiography; Embolism, Paradoxical; Foramen Ovale, Patent; Heparin; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Tomography, X-Ray Computed; Travel; Venous Thrombosis | 2011 |
Antiplatelet therapy in percutaneous coronary intervention: recent advances in oral antiplatelet agents.
Topics: Adenosine; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Drug Therapy, Combination; Humans; Piperazines; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Prasugrel Hydrochloride; Pyridines; Risk Factors; Thiophenes; Ticagrelor; Ticlopidine | 2010 |
Aspirin and clopidogrel resistance: methodological challenges and opportunities.
Topics: Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2010 |
Point-of-care testing for assessment of adequacy of oral antiplatelet therapy in patients with cardiovascular disease.
Topics: Administration, Oral; Aspirin; Cardiovascular Diseases; Clopidogrel; Cost-Benefit Analysis; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Point-of-Care Systems; Ticlopidine | 2010 |
Dosing strategies for antiplatelet therapy in percutaneous coronary intervention.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clinical Protocols; Clopidogrel; Drug Administration Schedule; Drug Monitoring; Hemorrhage; Humans; Patient Selection; Piperazines; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Risk Assessment; Risk Factors; Thiophenes; Thrombosis; Ticlopidine; Treatment Outcome | 2010 |
What goes into a major acute coronary syndrome trial and what will future trials look like?
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Clinical Trials as Topic; Clopidogrel; Cyclic N-Oxides; Eptifibatide; Heart Diseases; Humans; Peptides; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Pyridines; Research Design; Research Support as Topic; Risk Factors; Sample Size; Thiophenes; Ticagrelor; Ticlopidine; United Kingdom | 2010 |
Drug-eluting stent thrombosis 1,659 days after stent deployment: case report and literature review.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Agents; Clopidogrel; Coronary Angiography; Drug Administration Schedule; Drug-Eluting Stents; Electrocardiography; Humans; Male; Middle Aged; Neurosurgical Procedures; Platelet Aggregation Inhibitors; Risk Assessment; Risk Factors; Sirolimus; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2010 |
Residual platelet reactivity: predicting short- and long-term clinical outcome in patients undergoing percutaneous coronary revascularization.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Clopidogrel; Humans; Myocardial Ischemia; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Secondary Prevention; Ticlopidine | 2010 |
Revaluation of clopidogrel: let the data speak for themselves.
Topics: Arterial Occlusive Diseases; Aspirin; Clopidogrel; Cost-Benefit Analysis; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine | 2010 |
New antithrombotic agents--insights from clinical trials.
Topics: Adenosine; Anticoagulants; Aspirin; Clopidogrel; Coronary Thrombosis; Coumarins; Fibrinolytic Agents; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Thiophenes; Thromboembolism; Ticagrelor; Ticlopidine | 2010 |
Old and new molecular mechanisms associated with platelet resistance to antithrombotics.
Topics: Antithrombins; Aspirin; Blood Platelets; Clopidogrel; Humans; Patient Compliance; Ticlopidine | 2010 |
[Antiplatelet therapy in coronary heart disease. Some problems and achivements].
Topics: Acute Coronary Syndrome; Adenosine; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Aspirin; Blood Platelets; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug Interactions; Drug Resistance; Gastrointestinal Hemorrhage; Humans; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Genetic; Prasugrel Hydrochloride; Proton Pump Inhibitors; Purinergic P2Y Receptor Antagonists; Receptor, PAR-1; Thiophenes; Ticagrelor; Ticlopidine; United States; United States Food and Drug Administration | 2010 |
Safety evaluation of tirofiban.
Topics: Abciximab; Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clopidogrel; Double-Blind Method; Drug Resistance; Hemorrhage; Humans; Immunoglobulin Fab Fragments; Incidence; Multicenter Studies as Topic; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Randomized Controlled Trials as Topic; Thrombocytopenia; Ticlopidine; Tirofiban; Tyrosine | 2010 |
[Significance of platelet function tests].
Topics: Adenosine Diphosphate; Arachidonic Acid; Aspirin; Blood Platelet Disorders; Clopidogrel; Collagen; Hemorrhagic Disorders; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prognosis; Ristocetin; Ticlopidine | 2010 |
[Reduction of haemorrhagic risk in acute coronary syndromes].
Topics: Acute Coronary Syndrome; Anticoagulants; Aspirin; Clopidogrel; Fibrinolytic Agents; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine | 2011 |
Pharmacologic therapy for non ST-segment elevation acute coronary syndromes: focus on antithrombotic therapy.
Topics: Acute Coronary Syndrome; Adenosine; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Disease Management; Drug Synergism; Drug Therapy, Combination; Enoxaparin; Fibrinolytic Agents; Fondaparinux; Hemorrhage; Heparin; Hirudins; Humans; Peptide Fragments; Piperazines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Polysaccharides; Prasugrel Hydrochloride; Randomized Controlled Trials as Topic; Recombinant Proteins; Thiophenes; Ticagrelor; Ticlopidine | 2010 |
Controversies in oral antiplatelet therapy in patients undergoing aortocoronary bypass surgery.
Topics: Administration, Oral; Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Artery Bypass; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Pyridines; Thiophenes; Thrombosis; Ticlopidine | 2010 |
Controversies and future perspectives of antiplatelet therapy in secondary stroke prevention.
Topics: Aspirin; Blood-Brain Barrier; Cilostazol; Clopidogrel; Dipyridamole; Drug Interactions; Drug Therapy, Combination; Humans; Lactones; Naphthalenes; Platelet Aggregation Inhibitors; Propionates; Pyridines; Randomized Controlled Trials as Topic; Secondary Prevention; Stroke; Succinates; Tetrazoles; Thrombosis; Ticlopidine | 2010 |
A review of the use of common antiplatelet agents in orthopaedic practice.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Humans; Orthopedics; Perioperative Care; Platelet Aggregation Inhibitors; Preoperative Care; Stents; Thrombosis; Ticlopidine | 2010 |
Clinical Inquiries: Which drugs should post-MI patients routinely receive?
Topics: Angiotensin-Converting Enzyme Inhibitors; Aspirin; Atorvastatin; Clopidogrel; Eplerenone; Heptanoic Acids; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Pyrroles; Spironolactone; Ticlopidine | 2010 |
Platelet glycoprotein IIb/IIIa blockers during percutaneous coronary intervention and as the initial medical treatment of non-ST segment elevation acute coronary syndromes.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Fibrinolytic Agents; Hemorrhage; Heparin; Humans; Myocardial Infarction; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine | 2010 |
[Thienopyridines in the treatment and prevention of cardiovascular diseases. Part V. Combination of clopidogrel and acetylsalicylic acid in the treatment of stable patients with atherothrombotic cardiovascular diseases].
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Arteriosclerosis; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Circulation; Death, Sudden, Cardiac; Drug Therapy, Combination; Fibrinolytic Agents; Hemorrhage; Humans; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Pyridines; Randomized Controlled Trials as Topic; Risk Factors; Sex Factors; Streptokinase; Stroke; Thrombosis; Ticlopidine; Time Factors | 2010 |
A comparison of the metabolism of clopidogrel and prasugrel.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Carboxylic Ester Hydrolases; Clopidogrel; Cytochrome P-450 Enzyme System; Drug Therapy, Combination; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Prodrugs; Thiophenes; Thrombosis; Ticlopidine | 2010 |
Antithrombotic strategies in patients undergoing percutaneous coronary intervention for acute coronary syndrome.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Clinical Trials as Topic; Clopidogrel; Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2010 |
[New aspects on "triple therapy" after coronary stent implantation].
Topics: Administration, Oral; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Cross-Sectional Studies; Drug Therapy, Combination; Fibrinolytic Agents; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Prospective Studies; Registries; Risk Factors; Stents; Stroke; Thrombosis; Ticlopidine; Vitamin K | 2010 |
Aspirin and antiplatelet agent resistance: implications for prevention of secondary stroke.
Topics: Aspirin; Clopidogrel; Dipyridamole; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Secondary Prevention; Stroke; Ticlopidine | 2010 |
NSAID-induced gastrointestinal and cardiovascular injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Clopidogrel; Cyclooxygenase 2 Inhibitors; Drug Interactions; Gastrointestinal Diseases; Histamine H2 Antagonists; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Risk Assessment; Ticlopidine | 2010 |
Prevention of the renarrowing of coronary arteries using drug-eluting stents in the perioperative period: an update.
Topics: Aspirin; Blood Loss, Surgical; Clopidogrel; Coronary Thrombosis; Coronary Vessels; Drug-Eluting Stents; Humans; Myocardial Revascularization; Perioperative Care; Perioperative Period; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Ticlopidine | 2010 |
[Dilemma between gastroprotection and cardiovascular prevention].
Topics: Alleles; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Cytochrome P-450 CYP2C19; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Long-Term Care; Mutation; Omeprazole; Peptic Ulcer Hemorrhage; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Proton Pump Inhibitors; Randomized Controlled Trials as Topic; Recurrence; Risk Factors; Survival Analysis; Ticlopidine; Treatment Outcome | 2010 |
Effects of proton pump inhibitors on adverse gastrointestinal events in patients receiving clopidogrel: systematic review and meta-analysis.
Topics: Aspirin; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Gastrointestinal Diseases; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine | 2011 |
Oral antiplatelet therapy in stroke prevention. Minireview.
Topics: Administration, Oral; Aspirin; Clopidogrel; Dipyridamole; Drug Combinations; Humans; Ischemic Attack, Transient; Isoindoles; Phenylbutyrates; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2010 |
Ticagrelor: an investigational oral antiplatelet treatment for reduction of major adverse cardiac events in patients with acute coronary syndrome.
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Blood Platelets; Clopidogrel; Dyspnea; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Receptors, Purinergic P2Y12; Ticagrelor; Ticlopidine; Treatment Outcome | 2010 |
ACCF/ACG/AHA 2010 Expert Consensus Document on the concomitant use of proton pump inhibitors and thienopyridines: a focused update of the ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Aspirin; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Interactions; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Histamine H2 Antagonists; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Proton Pump Inhibitors; Purinergic P2Y Receptor Antagonists; Risk Factors; Thienopyridines; Thiophenes; Ticlopidine | 2010 |
Clopidogrel withdrawal: is there a "rebound" phenomenon?
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Humans; Patient Selection; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Risk Assessment; Risk Factors; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2011 |
Current status of antiplatelet agents to prevent stroke.
Topics: Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Secondary Prevention; Stroke; Ticlopidine | 2011 |
[Antithrombotic therapy in patients with prosthetic heart valves].
Topics: Anticoagulants; Aspirin; Blood Coagulation Tests; Clopidogrel; Drug Monitoring; Heart Valve Diseases; Heart Valve Prosthesis; Heart Valve Prosthesis Implantation; Hemorrhage; Humans; Monitoring, Physiologic; Platelet Aggregation Inhibitors; Prognosis; Thromboembolism; Ticlopidine; Warfarin | 2010 |
[Efficacy and safety of various doses of acetylsalicylic Acid in prevention of complications of atherothrombosis].
Topics: Aspirin; Blood Platelets; Blood Vessels; Cardiovascular Diseases; Cerebrovascular Disorders; Clinical Trials as Topic; Clopidogrel; Dose-Response Relationship, Drug; Drug Dosage Calculations; Humans; Peptic Ulcer Hemorrhage; Platelet Aggregation; Platelet Aggregation Inhibitors; Risk Assessment; Secondary Prevention; Stomach Ulcer; Thrombosis; Ticlopidine; Treatment Outcome | 2010 |
Contemporary management of coronary heart disease.
Topics: Acute Coronary Syndrome; Administration, Oral; Angina Pectoris; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coronary Disease; Electrocardiography; Fibrinolytic Agents; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Purinergic P2Y Receptor Agonists; Randomized Controlled Trials as Topic; Registries; Secondary Prevention; Ticlopidine; Time Factors; United Kingdom | 2010 |
ACCF/ACG/AHA 2010 expert consensus document on the concomitant use of proton pump inhibitors and thienopyridines: a focused update of the ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Aspirin; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Interactions; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Histamine H2 Antagonists; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Proton Pump Inhibitors; Purinergic P2Y Receptor Antagonists; Risk Factors; Thienopyridines; Thiophenes; Ticlopidine | 2010 |
Platelet function testing in clinical diagnostics.
Topics: Aspirin; Clopidogrel; Coronary Thrombosis; Hemorrhage; Humans; Intracranial Embolism; Intracranial Thrombosis; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Ticlopidine | 2011 |
[New approaches and indications for the analysis of platelet function in cardiology].
Topics: Acute Coronary Syndrome; Adenosine; Adenosine Monophosphate; Aspirin; Clopidogrel; Coronary Thrombosis; Drug Interactions; Hemorrhage; Humans; Piperazines; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Thiophenes; Ticagrelor; Ticlopidine | 2011 |
Safety and efficacy of triple antithrombotic therapy after percutaneous coronary intervention in patients needing long-term anticoagulation.
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Drug Therapy, Combination; Fibrinolytic Agents; Hemorrhage; Humans; Patient Selection; Risk Assessment; Risk Factors; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome; Warfarin | 2011 |
Meta-analysis of the combination of warfarin and dual antiplatelet therapy after coronary stenting in patients with indications for chronic oral anticoagulation.
Topics: Administration, Oral; Anticoagulants; Aspirin; Chronic Disease; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Treatment Outcome; Warfarin | 2011 |
Management of type-2 diabetes with anti-platelet therapies: special reference to aspirin.
Topics: Arachidonic Acid; Aspirin; Blood Platelets; Clopidogrel; Diabetes Mellitus, Type 2; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Thienopyridines; Ticlopidine; Vascular Diseases | 2011 |
[Novel agents in antiplatelet therapy].
Topics: Acute Coronary Syndrome; Adenosine; Adenosine Monophosphate; Aspirin; Clopidogrel; Humans; Lactones; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Pyridines; Receptors, Thrombin; Thiophenes; Ticagrelor; Ticlopidine | 2010 |
Antiplatelet therapy in the perioperative period.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Drug Therapy, Combination; Evidence-Based Medicine; Hemorrhage; Humans; Perioperative Period; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Stents; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2011 |
Clopidogrel plus aspirin versus aspirin alone for preventing cardiovascular disease.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine | 2011 |
Patients with drug-eluting stents and management of their anticoagulant therapy in cutaneous surgery.
Topics: Anticoagulants; Aspirin; Clopidogrel; Dermatologic Surgical Procedures; Drug-Eluting Stents; Humans; Perioperative Care; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine | 2011 |
Gastrointestinal bleeding after percutaneous coronary intervention.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Gastrointestinal Hemorrhage; Humans; Intestines; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine | 2011 |
Antiplatelet therapy in the perioperative period.
Topics: Aspirin; Clopidogrel; Humans; Perioperative Period; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Ticlopidine | 2010 |
[Coronary heart disease - what is of importance after coronary intervention?].
Topics: Adenosine; Aftercare; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coronary Disease; Drug Administration Schedule; Drug Approval; Drug Therapy, Combination; Drug-Eluting Stents; Gastrointestinal Hemorrhage; Humans; Myocardial Revascularization; Piperazines; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Prasugrel Hydrochloride; Proton Pump Inhibitors; Stents; Thiophenes; Ticagrelor; Ticlopidine | 2011 |
"Triple therapy" rather than "triple threat": a meta-analysis of the two antithrombotic regimens after stent implantation in patients receiving long-term oral anticoagulant treatment.
Topics: Administration, Oral; Anticoagulants; Aspirin; Clopidogrel; Drug Therapy, Combination; Heart Diseases; Humans; Platelet Aggregation Inhibitors; Stents; Stroke; Thromboembolism; Ticlopidine; Warfarin | 2011 |
Review article: proton pump inhibitors with clopidogrel--evidence for and against a clinically-important interaction.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Risk; Ticlopidine | 2011 |
Antiplatelet resistance in stroke.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Cyclooxygenase Inhibitors; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Risk; Secondary Prevention; Stroke; Ticlopidine | 2011 |
Platelet function and antiplatelet therapy in cardiovascular disease: implications of genetic polymorphisms.
Topics: Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Genetic Variation; Genotype; Haplotypes; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Genetic; Ticlopidine | 2011 |
Antiplatelet agents in cardiovascular disease.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine; Time Factors; United States | 2011 |
Antiplatelet therapy after placement of a drug-eluting stent: a review of efficacy and safety studies.
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine; Treatment Outcome | 2010 |
Monitoring the effectiveness of antiplatelet therapy: opportunities and limitations.
Topics: Aspirin; Clopidogrel; Drug Monitoring; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Stents; Thrombosis; Ticlopidine; Treatment Outcome | 2011 |
Triple therapy in hospitalized patients: facts and controversies.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Hospitalization; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Ticlopidine; Warfarin | 2011 |
The antithrombotic management of patients on oral anticoagulation undergoing coronary stent implantation: an update.
Topics: Administration, Oral; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Risk; Ticlopidine; Warfarin | 2012 |
[Strategy to manage low dose aspirin-induced gastrointestinal injury].
Topics: Anti-Ulcer Agents; Aspirin; Cardiovascular Diseases; Cerebrovascular Disorders; Clopidogrel; Famotidine; Gastric Mucosa; Humans; Omeprazole; Peptic Ulcer; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Proton Pump Inhibitors; Ticlopidine | 2011 |
[Prodrug technology in the development of medicinal agents].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aspirin; Clopidogrel; Drug Delivery Systems; Drug Design; Humans; Lansoprazole; Oseltamivir; Prodrugs; Simvastatin; Ticlopidine | 2011 |
Triple therapy: boon or bane for high-risk CV patients?
Topics: Acute Coronary Syndrome; Anticoagulants; Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Patient Selection; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Thiophenes; Ticlopidine; Warfarin | 2011 |
Secondary prevention in the acute and early chronic phase after ischaemic stroke and transient ischaemic attacks with antiplatelet drugs--is antiplatelet monotherapy still reasonable?
Topics: Abciximab; Acute Disease; Antibodies, Monoclonal; Aspirin; Chronic Disease; Clopidogrel; Delayed-Action Preparations; Dipyridamole; Drug Combinations; Humans; Immunoglobulin Fab Fragments; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Secondary Prevention; Stroke; Ticlopidine; Treatment Outcome | 2011 |
Proton pump inhibitors in rheumatic diseases: clinical practice, drug interactions, bone fractures and risk of infections.
Topics: Anticoagulants; Aryl Hydrocarbon Hydroxylases; Aspirin; Calcium, Dietary; Clopidogrel; Clostridioides difficile; Comorbidity; Cytochrome P-450 CYP2C19; Disease Susceptibility; Drug Interactions; Enterocolitis, Pseudomembranous; Fractures, Spontaneous; Gastrointestinal Hemorrhage; Humans; Hyperparathyroidism, Secondary; Infections; Osteoporosis; Proton Pump Inhibitors; Rheumatic Diseases; Risk; Thrombophilia; Ticlopidine | 2011 |
The influence of CYP2C19 polymorphisms on the pharmacokinetics, pharmacodynamics, and clinical effectiveness of P2Y(12) inhibitors.
Topics: Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Genotype; Humans; Pharmacogenetics; Phenotype; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Precision Medicine; Purinergic P2Y Receptor Antagonists; Ticlopidine; Treatment Outcome | 2011 |
Review and management of side effects associated with antiplatelet therapy for prevention of recurrent cerebrovascular events.
Topics: Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Headache; Hemorrhage; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Recurrence; Risk Factors; Stroke; Ticlopidine | 2011 |
P2Y receptors in health and disease.
Topics: Animals; Aspirin; Clopidogrel; Disease; Health; Humans; Platelet Activation; Receptors, Purinergic P2Y; Ticlopidine | 2011 |
Beyond aspirin and clopidogrel: is there a need for additional antiplatelet therapy in ACS?
Topics: Acute Coronary Syndrome; Adenosine; Adenosine Monophosphate; Aspirin; Cilostazol; Clopidogrel; Drug Therapy, Combination; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Quinazolinones; Receptors, Purinergic P2Y12; Sulfonamides; Tetrazoles; Thiophenes; Ticagrelor; Ticlopidine | 2011 |
Genetic determinants of on-clopidogrel high platelet reactivity.
Topics: Aryl Hydrocarbon Hydroxylases; Aryldialkylphosphatase; Aspirin; ATP Binding Cassette Transporter, Subfamily B; Biomarkers, Pharmacological; Blood Platelets; Clopidogrel; Drug Combinations; Genetic Testing; Humans; Liver; Mutation; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Prodrugs; Risk Factors; Thrombosis; Ticlopidine; Treatment Outcome | 2011 |
Antiplatelet drug therapy: role of pharmacodynamic and genetic testing.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Humans; Pharmacogenetics; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2011 |
Recent developments in the use of antiplatelet agents to prevent cardiovascular events.
Topics: Aryl Hydrocarbon Hydroxylases; Aspirin; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Interactions; Drug Therapy, Combination; Fibrinolytic Agents; Genetic Predisposition to Disease; Humans; Platelet Aggregation Inhibitors; Secondary Prevention; Ticlopidine | 2011 |
Clopidogrel hydrogen sulphate for atrial fibrillation.
Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Risk Factors; Stroke; Thrombosis; Ticlopidine | 2011 |
[ADP receptor blockers: new insights in the therapy and prophylaxis of ischemic heart disease].
Topics: Acute Coronary Syndrome; Adenosine Monophosphate; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Combined Modality Therapy; Humans; Myocardial Ischemia; Platelet Aggregation Inhibitors; Pyridines; Receptors, Purinergic P2; Stents; Ticlopidine | 2011 |
[Ticagrelor: a novel antiplatelet agent for patients with acute coronary syndrome].
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Clopidogrel; Drug Interactions; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Ticagrelor; Ticlopidine | 2011 |
Antiplatelet function variability in clopidogrel-treated patients: need for new antiplatelet agents.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Design; Drug Interactions; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2; Ticlopidine | 2012 |
The future of platelet function testing to guide therapy in clopidogrel low and enhanced responders.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Purinergic P2Y Receptor Antagonists; Ticlopidine | 2011 |
New insights in antiplatelet therapy for patients with ischemic stroke.
Topics: Aspirin; Atrial Fibrillation; Clopidogrel; Dipyridamole; Dose-Response Relationship, Drug; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2011 |
Clopidogrel and modified-release dipyridamole for the prevention of occlusive vascular events (review of Technology Appraisal No. 90): a systematic review and economic analysis.
Topics: Arterial Occlusive Diseases; Aspirin; Brain Ischemia; Clopidogrel; Cost-Benefit Analysis; Delayed-Action Preparations; Dipyridamole; Drug Therapy, Combination; Humans; Models, Economic; Myocardial Infarction; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Ticlopidine | 2011 |
[Resistance to antiplatelet drugs in patients with cerebrovascular disorders].
Topics: Arachidonate Lipoxygenases; Aspirin; Biotransformation; Blood Platelets; Clopidogrel; Dose-Response Relationship, Drug; Drug Resistance; Humans; Intracranial Thrombosis; Patient Compliance; Platelet Activation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Secondary Prevention; Ticlopidine | 2011 |
[New clinical concept and therapeutic strategy for TIA].
Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Diffusion Magnetic Resonance Imaging; Humans; Ischemic Attack, Transient; Middle Aged; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Risk; Secondary Prevention; Stroke; Tetrazoles; Ticlopidine; Time Factors | 2010 |
Platelet function monitoring in patients on clopidogrel: What should we learn from GRAVITAS?
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Clopidogrel; Humans; Monitoring, Physiologic; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2012 |
Anti-thrombotic medications for the neurointerventionist: aspirin and clopidogrel.
Topics: Aspirin; Clopidogrel; Fibrinolytic Agents; Humans; Nervous System Diseases; Neuroprotective Agents; Ticlopidine | 2010 |
High on treatment platelet reactivity.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Combined Modality Therapy; Cyclooxygenase Inhibitors; Drug Interactions; Drug Resistance; Humans; Myocardial Ischemia; Platelet Activation; Platelet Function Tests; Purinergic P2Y Receptor Antagonists; Stents; Thrombosis; Ticlopidine; Treatment Outcome | 2012 |
[Clopidogrel and stroke].
Topics: Acute Disease; Aspirin; Atrial Fibrillation; Clopidogrel; Drug Therapy, Combination; Humans; Inflammation; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Stroke; Ticlopidine | 2011 |
Antiplatelet therapy in the era of percutaneous coronary intervention with drug-eluting balloons.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Agents; Clopidogrel; Coated Materials, Biocompatible; Coronary Artery Disease; Coronary Restenosis; Drug Delivery Systems; Drug Therapy, Combination; Equipment Design; Evidence-Based Medicine; Humans; Patient Selection; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome | 2011 |
Anti-Platelet Therapy for Acute Coronary Syndrome: A Review of Currently Available Agents and What the Future Holds.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2011 |
[Decreasing incidence of stent thrombosis].
Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Immunoglobulin Fab Fragments; Incidence; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Recurrence; Risk Factors; Stents; Thrombosis; Ticlopidine; Treatment Outcome; Ventricular Dysfunction, Left | 2011 |
Antiplatelet options for secondary prevention in acute coronary syndromes.
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Piperazines; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Prasugrel Hydrochloride; Risk Factors; Secondary Prevention; Thiophenes; Ticagrelor; Ticlopidine | 2011 |
[Current coagulation diagnostics in intensive care medicine].
Topics: Anticoagulants; Aspirin; Blood Coagulation Tests; Clopidogrel; Cost-Benefit Analysis; Early Diagnosis; Fibrinolysis; Germany; Hemorrhagic Disorders; Humans; Partial Thromboplastin Time; Platelet Aggregation; Postoperative Hemorrhage; Predictive Value of Tests; Preoperative Care; Prothrombin Time; Thrombelastography; Ticlopidine | 2011 |
Clopidogrel and PPI interaction: clinically relevant or not?
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Humans; Male; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Thienopyridines; Ticlopidine | 2012 |
Safety and efficacy of antiplatelet and antithrombotic therapy in acute coronary syndrome patients with chronic kidney disease.
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Chronic Disease; Clinical Trials as Topic; Clopidogrel; Dose-Response Relationship, Drug; Factor Xa Inhibitors; Fibrinolytic Agents; Fondaparinux; Hemorrhage; Heparin; Hirudins; Humans; Kidney Diseases; Peptide Fragments; Piperazines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Polysaccharides; Prasugrel Hydrochloride; Recombinant Proteins; Thiophenes; Ticagrelor; Ticlopidine; Uremia | 2011 |
Antiplatelets in secondary stroke prevention: should clopidogrel be the first choice?
Topics: Aspirin; Clopidogrel; Dipyridamole; Humans; Ischemia; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Secondary Prevention; Stroke; Ticlopidine; Treatment Outcome | 2012 |
Unravelling the benefit against the risk of long-term dual antiplatelet therapy.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors; Treatment Outcome | 2011 |
The clinical relevance of response variability to antiplatelet therapy.
Topics: Aspirin; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2011 |
Antiplatelet agents and anticoagulants for hypertension.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Clopidogrel; Humans; Hypertension; Myocardial Infarction; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Thromboembolism; Ticlopidine; Warfarin | 2011 |
[Clopidogrel resistance--clinical significance, pathogenesis and potential solutions].
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Prevalence; Thrombosis; Ticlopidine | 2011 |
Antiplatelet therapy in ENT surgery: a review.
Topics: Aspirin; Blood Loss, Surgical; Clopidogrel; Decision Making; Drug-Eluting Stents; Humans; Otorhinolaryngologic Surgical Procedures; Perioperative Care; Platelet Aggregation Inhibitors; Risk Factors; Thrombosis; Ticlopidine | 2012 |
Unstable angina and non-ST elevation myocardial infarction.
Topics: Acute Coronary Syndrome; Adenosine; Angina, Unstable; Anticoagulants; Aspirin; Clopidogrel; Coronary Angiography; Echocardiography; Electrocardiography; Humans; Myocardial Infarction; Myocardial Revascularization; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Risk Factors; Thiophenes; Ticagrelor; Ticlopidine | 2012 |
Dual or mono antiplatelet therapy for patients with acute ischemic stroke or transient ischemic attack: systematic review and meta-analysis of randomized controlled trials.
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Aspirin; Brain Ischemia; Clopidogrel; Databases, Factual; Dipyridamole; Disease-Free Survival; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Recurrence; Stroke; Survival Rate; Ticlopidine | 2012 |
Oral antiplatelet therapy in patients with diabetes mellitus and acute coronary syndromes.
Topics: Acute Coronary Syndrome; Administration, Oral; Aspirin; Cilostazol; Clopidogrel; Diabetes Complications; Humans; Platelet Aggregation Inhibitors; Tetrazoles; Ticlopidine; Treatment Outcome | 2010 |
Cilostazol and primary-PCI: mirage or good alternative?
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Arrhythmias, Cardiac; Aspirin; Cilostazol; Clopidogrel; Combined Modality Therapy; Coronary Restenosis; Drug Therapy, Combination; Heart Failure; Humans; Phosphodiesterase 3 Inhibitors; Platelet Aggregation Inhibitors; Prodrugs; Risk; Stents; Tetrazoles; Thrombosis; Ticlopidine | 2012 |
Effects of combined aspirin and clopidogrel therapy on cardiovascular outcomes: a systematic review and meta-analysis.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Myocardial Infarction; Randomized Controlled Trials as Topic; Stroke; Ticlopidine; Treatment Outcome | 2012 |
Advances in antiplatelet therapy for acute coronary syndromes.
Topics: Acute Coronary Syndrome; Adenosine; Adenosine Monophosphate; Aspirin; Clopidogrel; Emergency Treatment; Female; Humans; Male; Patient Selection; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Quinazolinones; Sulfonamides; Thiophenes; Ticagrelor; Ticlopidine; Treatment Outcome | 2012 |
Optimal drug therapy after aspirin-induced upper gastrointestinal bleeding.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Gastrointestinal Hemorrhage; Humans; Peptic Ulcer; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Risk Factors; Ticlopidine | 2012 |
Current trial-associated outcomes with warfarin in prevention of stroke in patients with nonvalvular atrial fibrillation: a meta-analysis.
Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Azetidines; Benzylamines; Brain Ischemia; Clopidogrel; Female; Humans; Incidence; Male; Oligosaccharides; Primary Prevention; Pyrazoles; Pyridones; Randomized Controlled Trials as Topic; Stroke; Ticlopidine; Treatment Outcome; United States; Warfarin | 2012 |
What do you do with the antiplatelet agents in patients with drug eluting stents who then receive a mechanical valve?
Topics: Administration, Oral; Angioplasty, Balloon, Coronary; Animals; Anticoagulants; Aspirin; Benchmarking; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Evidence-Based Medicine; Female; Heart Valve Prosthesis; Heart Valve Prosthesis Implantation; Hemorrhage; Humans; Male; Middle Aged; Paclitaxel; Platelet Aggregation Inhibitors; Prosthesis Design; Risk Assessment; Risk Factors; Sirolimus; Thrombosis; Ticlopidine; Treatment Outcome | 2012 |
Perioperative management of antiplatelet agents in patients undergoing cardiac surgery.
Topics: Adenosine; Adenosine Monophosphate; Aspirin; Clopidogrel; Coronary Artery Bypass; Humans; Perioperative Care; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticagrelor; Ticlopidine | 2012 |
Current antiplatelet options for NSTE-ACS patients.
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Biological Availability; Clopidogrel; Comparative Effectiveness Research; Drug Monitoring; Drug Synergism; Drug Therapy, Combination; Electrocardiography; Humans; Pharmacovigilance; Piperazines; Platelet Activation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Randomized Controlled Trials as Topic; Receptors, Purinergic P2Y; Risk Assessment; Thiophenes; Ticagrelor; Ticlopidine; Treatment Outcome | 2012 |
Use of aspirin and clopidogrel after coronary artery bypass graft surgery.
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Artery Bypass; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2012 |
Switching antiplatelet regimens: alternatives to clopidogrel in patients with acute coronary syndrome undergoing PCI: a review of the literature and practical considerations for the interventional cardiologist.
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Clopidogrel; Coronary Thrombosis; Drug Interactions; Drug Substitution; Drug Therapy, Combination; Humans; Percutaneous Coronary Intervention; Pharmacogenetics; Piperazines; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Thiophenes; Ticagrelor; Ticlopidine; Time Factors; Treatment Outcome | 2013 |
The effectiveness and safety of triple-antiplatelet treatment based on cilostazol for patients receiving percutaneous coronary intervention: a meta-analysis.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Clopidogrel; Confidence Intervals; Coronary Artery Disease; Coronary Restenosis; Drug Therapy, Combination; Humans; Odds Ratio; Platelet Aggregation Inhibitors; Tetrazoles; Ticlopidine | 2012 |
Clopidogrel and proton pump inhibitors--where do we stand in 2012?
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Aspirin; Biotransformation; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Interactions; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Risk Assessment; Risk Factors; Ticlopidine | 2012 |
Prevention of stroke in patients with atrial fibrillation: anticoagulant and antiplatelet options.
Topics: Anticoagulants; Antithrombins; Aspirin; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Clopidogrel; Dabigatran; Hemorrhage; Humans; Morpholines; Practice Guidelines as Topic; Pyrazoles; Pyridines; Pyridones; Risk Assessment; Rivaroxaban; Stroke; Thiazoles; Thiophenes; Thrombolytic Therapy; Ticlopidine; Warfarin | 2012 |
Latest evidence in personalized antiplatelet therapy in patients with acute coronary syndromes undergoing percutaneous coronary intervention.
Topics: Acute Coronary Syndrome; Aryl Hydrocarbon Hydroxylases; Aryldialkylphosphatase; Aspirin; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Interactions; Drug Resistance; Evidence-Based Medicine; Genotype; Humans; Percutaneous Coronary Intervention; Piperazines; Platelet Aggregation Inhibitors; Platelet Function Tests; Postoperative Complications; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Thiophenes; Ticlopidine | 2012 |
Use of cilostazol in percutaneous coronary interventions.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Phosphodiesterase 3 Inhibitors; Platelet Aggregation Inhibitors; Tetrazoles; Ticlopidine; Vasodilator Agents | 2012 |
Utility of platelet transfusion in adult patients with traumatic intracranial hemorrhage and preinjury antiplatelet use: a systematic review.
Topics: Adult; Aspirin; Clopidogrel; Cohort Studies; Emergency Service, Hospital; Evidence-Based Medicine; Female; Hospital Mortality; Humans; Injury Severity Score; Intracranial Hemorrhage, Traumatic; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Transfusion; Prognosis; Registries; Retrospective Studies; Risk Assessment; Survival Analysis; Ticlopidine; Trauma Centers; Treatment Outcome | 2012 |
Ticagrelor: a P2Y12 antagonist for use in acute coronary syndromes.
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Blood Platelets; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Humans; Kaplan-Meier Estimate; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Product Surveillance, Postmarketing; Purinergic P2Y Receptor Antagonists; Thiophenes; Ticagrelor; Ticlopidine | 2012 |
Interindividual variability in the efficacy of oral antiplatelet drugs: definitions, mechanisms and clinical importance.
Topics: Administration, Oral; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Comorbidity; Drug Interactions; Drug Resistance; Genotype; Humans; Medication Adherence; Patient Selection; Phenotype; Platelet Aggregation Inhibitors; Platelet Function Tests; Risk Factors; Ticlopidine; Treatment Outcome | 2012 |
Development and clinical use of prasugrel and ticagrelor.
Topics: Acute Coronary Syndrome; Adenosine; Animals; Aspirin; Blood Platelets; Clopidogrel; Drug Design; Hemorrhage; Hemostasis; Humans; Patient Selection; Piperazines; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Risk Factors; Thiophenes; Ticagrelor; Ticlopidine; Treatment Outcome | 2012 |
Challenges and perspectives of antiplatelet therapy in patients with diabetes mellitus and coronary artery disease.
Topics: Aspirin; Blood Glucose; Blood Platelets; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Humans; Insulin; Insulin Resistance; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine; Treatment Outcome | 2012 |
Tailoring antiplatelet therapy: a step toward individualized therapy to improve clinical outcome?
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Blood Platelets; Clopidogrel; Coronary Thrombosis; Drug Interactions; Drug Resistance; Genotype; Hemorrhage; Humans; Patient Selection; Percutaneous Coronary Intervention; Pharmacogenetics; Phenotype; Piperazines; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Precision Medicine; Predictive Value of Tests; Receptors, Purinergic P2Y12; Risk Assessment; Risk Factors; Thiophenes; Ticagrelor; Ticlopidine; Treatment Outcome | 2012 |
Investigating incoherence gives insight: clopidogrel is equivalent to extended-release dipyridamole plus aspirin in secondary stroke prevention.
Topics: Aspirin; Clopidogrel; Confounding Factors, Epidemiologic; Dipyridamole; Drug Therapy, Combination; Humans; Logistic Models; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2012 |
Cilostazol added to aspirin and clopidogrel reduces revascularization without increases in major adverse events in patients with drug-eluting stents: a meta-analysis of randomized controlled trials.
Topics: Aspirin; Cardiovascular Diseases; Cilostazol; Clopidogrel; Coronary Restenosis; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Tetrazoles; Ticlopidine | 2013 |
Anticoagulants for the treatment of acute coronary syndrome in the era of new oral agents.
Topics: Acute Coronary Syndrome; Administration, Oral; Anticoagulants; Antithrombins; Aspirin; Benzimidazoles; beta-Alanine; Clopidogrel; Dabigatran; Drug Therapy, Combination; Factor Xa Inhibitors; Hemorrhage; Heparin; Humans; Morpholines; Platelet Aggregation Inhibitors; Pyrazoles; Pyridones; Rivaroxaban; Thiophenes; Ticlopidine; Warfarin | 2012 |
Advances in platelet function testing assessing bleeding complications in patients with coronary artery disease.
Topics: Acute Coronary Syndrome; Aspirin; Blood Platelets; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Hemorrhage; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Function Tests; Precision Medicine; Risk; Thrombosis; Ticlopidine | 2012 |
Effect of addition of clopidogrel to aspirin on mortality: systematic review of randomized trials.
Topics: Adult; Aged; Aspirin; Cause of Death; Cerebral Hemorrhage; Clopidogrel; Data Interpretation, Statistical; Double-Blind Method; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine; Treatment Outcome | 2012 |
A meta-analysis of randomized controlled trials appraising the efficacy and safety of cilostazol after coronary artery stent implantation.
Topics: Aspirin; Blood Vessel Prosthesis; Blood Vessel Prosthesis Implantation; Cilostazol; Clopidogrel; Combined Modality Therapy; Coronary Restenosis; Drug Therapy, Combination; Female; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Pyridines; Randomized Controlled Trials as Topic; Stents; Tetrazoles; Ticlopidine; Treatment Outcome | 2012 |
Cilostazol-based triple antiplatelet therapy compared to dual antiplatelet therapy in patients with coronary stent implantation: a meta-analysis of 5,821 patients.
Topics: Acute Coronary Syndrome; Aspirin; Blood Vessel Prosthesis; Blood Vessel Prosthesis Implantation; Cilostazol; Clopidogrel; Coronary Restenosis; Drug Therapy, Combination; Hemorrhage; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stents; Stroke; Tetrazoles; Ticlopidine; Treatment Outcome | 2012 |
A meta-analysis to determine the effect of preinjury antiplatelet agents on mortality in patients with blunt head trauma.
Topics: Aged; Anticoagulants; Aspirin; Blood Coagulation Disorders; Clopidogrel; Epidemiologic Methods; Head Injuries, Closed; Humans; Intracranial Hemorrhage, Traumatic; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine | 2013 |
Impact of antiplatelet therapy in heart disease.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Heart Diseases; Humans; Myocardial Infarction; Platelet Activation; Platelet Aggregation Inhibitors; Thromboembolism; Ticlopidine; Treatment Outcome | 2012 |
Clopidogrel in coronary artery disease: update 2012.
Topics: Adenosine; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Humans; Myocardial Infarction; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Thiophenes; Ticagrelor; Ticlopidine; Treatment Outcome | 2012 |
Stents and antiplatelet therapy.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug-Eluting Stents; Humans; Platelet Aggregation Inhibitors; Prosthesis Design; Risk Factors; Stents; Thienopyridines; Thrombosis; Ticlopidine | 2012 |
Bleeding and the use of antiplatelet agents in the management of acute coronary syndromes and atrial fibrillation.
Topics: Acute Coronary Syndrome; Aspirin; Atrial Fibrillation; Clinical Trials as Topic; Clopidogrel; Hemorrhage; Hospital Mortality; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Purinergic P2Y Receptor Antagonists; Risk Assessment; Ticlopidine | 2012 |
Antiplatelet therapy in stroke prevention.
Topics: Aspirin; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Primary Prevention; Randomized Controlled Trials as Topic; Secondary Prevention; Stroke; Ticlopidine | 2012 |
Challenges in atrial fibrillation.
Topics: Aspirin; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Clopidogrel; Dabigatran; Drug Therapy, Combination; Humans; International Normalized Ratio; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2012 |
Variability of platelet indices and function: acquired and genetic factors.
Topics: Aspirin; Blood Platelets; Cell Size; Clopidogrel; Genome-Wide Association Study; Humans; Platelet Count; Polymorphism, Single Nucleotide; Ticlopidine | 2012 |
The role of laboratory monitoring in antiplatelet therapy.
Topics: Aspirin; Blood Platelets; Clopidogrel; Cost-Benefit Analysis; Humans; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Ticlopidine | 2012 |
Antiplatelet therapy in cerebrovascular disorders.
Topics: Anticoagulants; Aspirin; Cerebrovascular Disorders; Clopidogrel; Dipyridamole; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2012 |
Primary prevention of ischaemic cardiovascular disorders with antiplatelet agents.
Topics: Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Humans; Ischemia; Myocardial Infarction; Platelet Aggregation Inhibitors; Stroke; Thrombosis; Ticlopidine | 2012 |
Antiplatelet treatment in primary and secondary stroke prevention in women.
Topics: Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Female; Humans; Naphthalenes; Platelet Aggregation Inhibitors; Primary Prevention; Propionates; Salicylates; Secondary Prevention; Sex Factors; Stroke; Ticlopidine | 2012 |
Mechanisms of variability in antiplatelet agents response.
Topics: Aspirin; Biotransformation; Clopidogrel; Drug Monitoring; Drug Resistance; Genotype; Humans; Patient Selection; Pharmacogenetics; Phenotype; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Precision Medicine; Predictive Value of Tests; Ticlopidine | 2012 |
Antithrombotic therapy.
Topics: Animals; Anticoagulants; Aspirin; Blood Coagulation Disorders; Cat Diseases; Cats; Clopidogrel; Dog Diseases; Dogs; Heparin; Platelet Aggregation Inhibitors; Thromboembolism; Ticlopidine; Warfarin | 2012 |
Clopidogrel: the data, the experience, and the controversies.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Complications; Purinergic P2Y Receptor Antagonists; Ticlopidine | 2012 |
A critical overview on ticagrelor in acute coronary syndromes.
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Clopidogrel; Double-Blind Method; Female; Humans; Male; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Randomized Controlled Trials as Topic; Risk Assessment; Ticagrelor; Ticlopidine; Treatment Outcome | 2013 |
[Antithrombotic therapy after peripheral vascular treatment: what is evidence-based?].
Topics: Aortic Diseases; Aspirin; Blood Vessel Prosthesis Implantation; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endarterectomy; Evidence-Based Medicine; Femoral Artery; Fibrinolytic Agents; Follow-Up Studies; Humans; Iliac Artery; International Normalized Ratio; Peripheral Arterial Disease; Polyethylene Terephthalates; Polytetrafluoroethylene; Popliteal Artery; Postoperative Complications; Prosthesis Design; Ticlopidine; Veins; Vitamin K | 2012 |
Adenosine-diphosphate (ADP) receptor antagonists for the prevention of cardiovascular disease in type 2 diabetes mellitus.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Diabetes Mellitus, Type 2; Dipyridamole; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Randomized Controlled Trials as Topic; Ticlopidine | 2012 |
Clopidogrel, aspirin and proton pump inhibition after percutaneous valve implants: an update.
Topics: Aspirin; Clopidogrel; Heart Valve Prosthesis Implantation; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Review Literature as Topic; Ticlopidine | 2013 |
[Novel agents for antithrombotic therapy in cardiology].
Topics: Adenosine; Administration, Oral; Anticoagulants; Aspirin; Clopidogrel; Coumarins; Fibrinolytic Agents; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Thiophenes; Thrombolytic Therapy; Ticagrelor; Ticlopidine | 2012 |
Antiplatelet drug resistance and variability in response: the role of antiplatelet therapy monitoring.
Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Cost Savings; Drug Monitoring; Drug Resistance; Drug Substitution; Drug Therapy, Combination; Humans; Ischemia; Platelet Aggregation Inhibitors; Secondary Prevention; Thrombosis; Ticlopidine | 2013 |
Acute ischemic cerebrovascular events on antiplatelet therapy: what is the optimal prevention strategy?
Topics: Aspirin; Brain Ischemia; Clopidogrel; Dipyridamole; Dose-Response Relationship, Drug; Humans; Life Style; Medication Adherence; Patient Education as Topic; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Risk Factors; Stroke; Ticlopidine | 2013 |
Aspirin and clopidogrel resistance: possible mechanisms and clinical relevance. Part I: Concept of resistance.
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Resistance; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2012 |
Drug interactions in the treatment of depression in patients with ischemic heart disease.
Topics: Aged; Antidepressive Agents; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Comorbidity; Cytochrome P-450 CYP2C19; Depressive Disorder, Major; Drug Interactions; Drug Therapy, Combination; Early Diagnosis; Fluoxetine; Fluvoxamine; Gastrointestinal Hemorrhage; Genotype; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Platelet Aggregation Inhibitors; Proportional Hazards Models; Risk Factors; Selective Serotonin Reuptake Inhibitors; Ticlopidine | 2012 |
Aspirin and clopidogrel for prevention of ischemic stroke.
Topics: Aspirin; Brain Ischemia; Clopidogrel; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Secondary Prevention; Stroke; Ticlopidine | 2013 |
Antiplatelet drug use in patients with non-ST-segment elevation acute coronary syndromes.
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Ticagrelor; Ticlopidine | 2013 |
Controversies in the use & implementation of drug-eluting stent technology.
Topics: Absorbable Implants; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Coated Materials, Biocompatible; Coronary Restenosis; Cytochrome P-450 CYP2C19; Drug Resistance; Drug-Eluting Stents; History, 20th Century; History, 21st Century; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Ticlopidine | 2012 |
Considerations in antithrombotic therapy among patients undergoing transcatheter aortic valve implantation.
Topics: Aortic Valve Stenosis; Aspirin; Cardiac Catheterization; Clopidogrel; Fibrinolytic Agents; Heart Valve Prosthesis; Humans; Myocardial Ischemia; Platelet Aggregation Inhibitors; Postoperative Complications; Practice Guidelines as Topic; Ticlopidine; Time Factors | 2013 |
Expert position paper on the use of proton pump inhibitors in patients with cardiovascular disease and antithrombotic therapy.
Topics: Adenosine; Aspirin; Benzimidazoles; beta-Alanine; Cardiovascular Diseases; Clopidogrel; Dabigatran; Drug Interactions; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Proton Pump Inhibitors; Purinergic P2Y Receptor Antagonists; Thiophenes; Ticagrelor; Ticlopidine; Warfarin | 2013 |
Clinical consequences of aspirin and clopidogrel resistance: an overview.
Topics: Aryl Hydrocarbon Hydroxylases; Aspirin; Cerebrovascular Disorders; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Resistance; Female; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine | 2013 |
Addition of cilostazol to conventional dual antiplatelet therapy reduces the risk of cardiac events and restenosis after drug-eluting stent implantation: a meta-analysis.
Topics: Aspirin; Cilostazol; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Female; Heart Diseases; Humans; Male; Middle Aged; Myocardial Revascularization; Odds Ratio; Platelet Aggregation Inhibitors; Risk; Tetrazoles; Ticlopidine | 2013 |
Dual antiplatelet therapy in patients with diabetes mellitus: special considerations.
Topics: Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Diabetes Mellitus; Diabetic Angiopathies; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2013 |
Dual anti-platelet therapy after coronary artery bypass grafting: is there any benefit? A systematic review and meta-analysis.
Topics: Angina Pectoris; Aspirin; Clopidogrel; Coronary Artery Bypass; Drug Therapy, Combination; Graft Occlusion, Vascular; Humans; Models, Statistical; Myocardial Infarction; Platelet Aggregation Inhibitors; Postoperative Care; Postoperative Complications; Postoperative Hemorrhage; Randomized Controlled Trials as Topic; Ticlopidine; Treatment Outcome | 2013 |
Monitoring aspirin and clopidogrel response: testing controversies and recommendations.
Topics: Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Function Tests; Precision Medicine; Stents; Thrombosis; Ticlopidine | 2013 |
Aspirin and clopidogrel resistance: possible mechanisms and clinical relevance. Part II: Potential causes and laboratory tests.
Topics: Age Factors; Aspirin; Biological Availability; Clopidogrel; Drug Administration Schedule; Drug Interactions; Drug Resistance; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Genetic; Sex Factors; Signal Transduction; Thromboxanes; Ticlopidine | 2013 |
Efficacy and safety of triple-antiplatelet therapy after percutaneous coronary intervention: a meta-analysis.
Topics: Aspirin; Cilostazol; Clopidogrel; Drug Therapy, Combination; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Publication Bias; Stents; Tetrazoles; Ticlopidine | 2013 |
Effect of addition of clopidogrel to aspirin on stroke incidence: Meta-analysis of randomized trials.
Topics: Aged; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Humans; Incidence; Male; Middle Aged; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stroke; Ticlopidine | 2015 |
Triple therapy (aspirin, clopidogrel and oral anticoagulant) after percutaneous coronary intervention: another call for personalized medicine.
Topics: Administration, Oral; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Drug Therapy, Combination; Humans; Percutaneous Coronary Intervention; Postoperative Complications; Ticlopidine | 2013 |
Pharmacokinetic considerations for antithrombotic therapies in stroke.
Topics: Administration, Oral; Anticoagulants; Aspirin; Atrial Fibrillation; Cilostazol; Clopidogrel; Factor Xa; Factor Xa Inhibitors; Fibrinolytic Agents; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Risk Factors; Stroke; Tetrazoles; Thiophenes; Thrombin; Ticlopidine; Vitamin K | 2013 |
Aspirin, clopidogrel, and ticagrelor in acute coronary syndromes.
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Interactions; Humans; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Secondary Prevention; Ticagrelor; Ticlopidine; Treatment Outcome; United States | 2013 |
Closing the loop: a 21-year audit of strategies for preventing stroke and death following carotid endarterectomy.
Topics: Angioscopy; Aspirin; Carotid Artery Diseases; Clinical Protocols; Clopidogrel; Drug Therapy, Combination; Endarterectomy, Carotid; Humans; Hypertension; Intracranial Embolism; Intracranial Hemorrhages; Intraoperative Care; Medical Audit; Platelet Aggregation Inhibitors; Postoperative Care; Practice Guidelines as Topic; Predictive Value of Tests; Quality of Health Care; Risk Factors; Stroke; Ticlopidine; Time Factors; Treatment Outcome; Ultrasonography, Doppler, Transcranial | 2013 |
[Secondary prevention with clopidogrel after TIA or stroke].
Topics: Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Netherlands; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Secondary Prevention; Stroke; Ticlopidine; Treatment Outcome | 2013 |
Late and very late stent thrombosis in patients with second-generation drug-eluting stents.
Topics: Aspirin; Cardiotonic Agents; Clopidogrel; Drug-Eluting Stents; Everolimus; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prosthesis Design; Sirolimus; Thrombosis; Ticlopidine; Time Factors | 2013 |
The efficacy and adverse reaction of bleeding of clopidogrel plus aspirin as compared to aspirin alone after stroke or TIA: a systematic review.
Topics: Aspirin; Bleeding Time; Clopidogrel; Hemorrhage; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stroke; Ticlopidine; Treatment Outcome | 2013 |
Use of antiplatelet drugs in the treatment of acute coronary syndromes.
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Angina, Unstable; Aspirin; Clinical Trials as Topic; Clopidogrel; Female; Humans; Male; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Ticlopidine | 2013 |
Comparison of on-treatment platelet reactivity between triple antiplatelet therapy with cilostazol and standard dual antiplatelet therapy in patients undergoing coronary interventions: a meta-analysis.
Topics: Aspirin; Blood Platelets; Cilostazol; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Humans; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Tetrazoles; Thromboembolism; Ticlopidine | 2013 |
High on-treatment platelet reactivity in peripheral endovascular procedures.
Topics: Aspirin; Atherosclerosis; Blood Platelets; Clopidogrel; Endovascular Procedures; Humans; Peripheral Arterial Disease; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2014 |
Perioperative management of antiplatelet therapy in patients with a coronary stent who need noncardiac surgery: a systematic review of clinical practice guidelines.
Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Elective Surgical Procedures; Hemorrhage; Humans; Metals; Perioperative Care; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Stents; Thromboembolism; Ticlopidine; Time Factors; Withholding Treatment | 2013 |
Clopidogrel, prasugrel, or ticagrelor? a practical guide to use of antiplatelet agents in patients with acute coronary syndromes.
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Clopidogrel; Decision Support Techniques; Drug Therapy, Combination; Humans; Induction Chemotherapy; Maintenance Chemotherapy; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Prasugrel Hydrochloride; Thiophenes; Ticagrelor; Ticlopidine | 2013 |
[The most important aspects of risk assessment].
Topics: Algorithms; Aspirin; Cardiovascular Diseases; Clopidogrel; Digestive System Surgical Procedures; Drug Substitution; Drug Therapy, Combination; Health Status Indicators; Hemorrhage; Heparin; Humans; Perioperative Period; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Risk Assessment; Thromboembolism; Ticlopidine; Viscera | 2013 |
Focused 2012 update of the Canadian Cardiovascular Society guidelines for the use of antiplatelet therapy.
Topics: Acute Coronary Syndrome; Adenosine; Anticoagulants; Aspirin; Clinical Trials as Topic; Clopidogrel; Contraindications; Coronary Artery Bypass; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Hemorrhage; Humans; Myocardial Infarction; Percutaneous Coronary Intervention; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Proton Pump Inhibitors; Secondary Prevention; Stents; Stroke; Thiophenes; Thrombosis; Ticagrelor; Ticlopidine | 2013 |
[Oral antiplatelet agents can still be used along with proton pump inhibitors in spite of drug interactions].
Topics: Adenosine; Administration, Oral; Aspirin; Clopidogrel; Cyclooxygenase Inhibitors; Drug Interactions; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Piperazines; Prasugrel Hydrochloride; Proton Pump Inhibitors; Purinergic P2Y Receptor Antagonists; Risk Factors; Thienopyridines; Thiophenes; Ticagrelor; Ticlopidine | 2013 |
Aggressive medical therapy alone is not adequate in certain patients with severe symptomatic carotid stenosis.
Topics: Aspirin; Atorvastatin; Carotid Artery Diseases; Clopidogrel; Constriction, Pathologic; Endovascular Procedures; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Middle Aged; Platelet Aggregation Inhibitors; Pyrroles; Ticlopidine | 2013 |
Risk-benefit profile of long-term dual- versus single-antiplatelet therapy among patients with ischemic stroke: a systematic review and meta-analysis.
Topics: Anticoagulants; Aspirin; Brain Ischemia; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; Intracranial Hemorrhages; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Risk Assessment; Secondary Prevention; Stroke; Ticlopidine | 2013 |
Long-term clinical efficacy and safety of adding cilostazol to dual antiplatelet therapy for patients undergoing PCI: a meta-analysis of randomized trials with adjusted indirect comparisons.
Topics: Aspirin; Cilostazol; Clopidogrel; Coronary Thrombosis; Drug Therapy, Combination; Hemorrhage; Humans; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Tetrazoles; Ticlopidine; Treatment Outcome | 2014 |
[Thrombocyte aggregation inhibitors: what are the risks?].
Topics: Adenosine; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Disease; Drug Interactions; Drug Resistance; Drug Therapy, Combination; Hemorrhage; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Randomized Controlled Trials as Topic; Risk Factors; Stents; Thiophenes; Ticagrelor; Ticlopidine | 2013 |
Anticoagulant and antiplatelet medications encountered in emergency surgery patients: a review of reversal strategies.
Topics: Anticoagulants; Aspirin; Benzimidazoles; Clopidogrel; Dabigatran; Emergencies; Enoxaparin; Fondaparinux; Heparin; Humans; Morpholines; Platelet Aggregation Inhibitors; Platelet Transfusion; Polysaccharides; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Surgical Procedures, Operative; Thiophenes; Ticlopidine; Warfarin | 2013 |
The challenge of stroke prevention with intracranial arterial stenosis.
Topics: Aspirin; Carotid Artery, Common; Carotid Stenosis; Clopidogrel; Constriction, Pathologic; Drug Therapy, Combination; Female; Fibrinolytic Agents; Humans; Intracranial Arteriosclerosis; Male; Platelet Aggregation Inhibitors; Risk Factors; Risk Reduction Behavior; Secondary Prevention; Stroke; Ticlopidine; Treatment Outcome; United States; Warfarin | 2013 |
Triple versus dual antiplatelet therapy in acute coronary syndromes: adding cilostazol to aspirin and clopidogrel?
Topics: Acute Coronary Syndrome; Aspirin; Cilostazol; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Humans; Phosphodiesterase 3 Inhibitors; Platelet Aggregation Inhibitors; Tetrazoles; Ticlopidine | 2013 |
Use of antiplatelet agents in patients with atherosclerotic disease.
Topics: Acute Coronary Syndrome; Adenosine; Aged; Aspirin; Atherosclerosis; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Risk Factors; Thiophenes; Ticagrelor; Ticlopidine | 2013 |
Dual antiplatelet therapy -- management in general practice.
Topics: Acute Coronary Syndrome; Adenosine; Aged; Aspirin; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Piperazines; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Prasugrel Hydrochloride; Thiophenes; Ticagrelor; Ticlopidine | 2013 |
Platelet glycoprotein IIb/IIIa blockers during percutaneous coronary intervention and as the initial medical treatment of non-ST segment elevation acute coronary syndromes.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Cause of Death; Fibrinolytic Agents; Hemorrhage; Heparin; Humans; Myocardial Infarction; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine | 2013 |
Combination of a new oral anticoagulant, aspirin and clopidogrel after acute coronary syndrome: new therapeutic standard?
Topics: Acute Coronary Syndrome; Administration, Oral; Anticoagulants; Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Drug Combinations; Humans; Platelet Aggregation Inhibitors; Secondary Prevention; Ticlopidine | 2013 |
Evaluation of antiplatelet agents for secondary prevention of stroke using mixed treatment comparison meta-analysis.
Topics: Aged; Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Precision Medicine; Randomized Controlled Trials as Topic; Risk Factors; Secondary Prevention; Stroke; Ticlopidine | 2013 |
Platelet glycoprotein IIb/IIIa blockers during percutaneous coronary intervention and as the initial medical treatment of non-ST segment elevation acute coronary syndromes.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Fibrinolytic Agents; Hemorrhage; Heparin; Humans; Myocardial Infarction; Platelet Glycoprotein GPIIb-IIIa Complex; Randomized Controlled Trials as Topic; Ticlopidine | 2013 |
Antiplatelet therapy to prevent recurrent stroke: Three good options.
Topics: Aspirin; Carotid Stenosis; Clopidogrel; Dipyridamole; Humans; Platelet Aggregation Inhibitors; Secondary Prevention; Stents; Stroke; Ticlopidine | 2013 |
[Antiplatelet therapy: resistance to traditional antiaggregation drugs and role of new antiplatelet agents].
Topics: Acute Coronary Syndrome; Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Ticlopidine | 2014 |
Antiplatelet treatment for prevention of cerebrovascular events in patients with vascular diseases: a systematic review and meta-analysis.
Topics: Adenosine; Aged; Aspirin; Cerebral Hemorrhage; Cerebrovascular Disorders; Clopidogrel; Cohort Studies; Data Interpretation, Statistical; Drug Therapy, Combination; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Piperazines; Platelet Aggregation Inhibitors; Population; Prasugrel Hydrochloride; Randomized Controlled Trials as Topic; Receptors, Purinergic P2; Secondary Prevention; Stroke; Thiophenes; Ticagrelor; Ticlopidine; Vascular Diseases | 2014 |
[Differentiated antiplatelet therapy for acute coronary syndromes].
Topics: Acute Coronary Syndrome; Adenosine; Angina, Unstable; Aspirin; Blood Platelets; Clopidogrel; Hemorrhage; Humans; Myocardial Infarction; Piperazines; Platelet Aggregation Inhibitors; Platelet Transfusion; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Thiophenes; Ticagrelor; Ticlopidine | 2014 |
p2y12 receptor inhibitors in acute coronary syndromes: from the research laboratory to the clinic and vice versa.
Topics: Acute Coronary Syndrome; Aspirin; Clinical Trials as Topic; Clopidogrel; Diabetic Angiopathies; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Renal Insufficiency, Chronic; Ticlopidine; Treatment Outcome | 2014 |
Anticoagulation and antiplatelet therapy in acute coronary syndromes.
Topics: Acute Coronary Syndrome; Adenosine; Anticoagulants; Aspirin; Benzimidazoles; beta-Alanine; Clopidogrel; Dabigatran; Enoxaparin; Fondaparinux; Heparin; Hirudins; Humans; Morpholines; Peptide Fragments; Piperazines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Polysaccharides; Prasugrel Hydrochloride; Pyrazoles; Pyridones; Recombinant Proteins; Rivaroxaban; Thiophenes; Ticagrelor; Ticlopidine; Warfarin | 2014 |
Lack of association between dual antiplatelet therapy use and stent thrombosis between 1 and 12 months following resolute zotarolimus-eluting stent implantation.
Topics: Aspirin; Blood Vessel Prosthesis; Clinical Trials as Topic; Clopidogrel; Coronary Thrombosis; Death, Sudden, Cardiac; Drug-Eluting Stents; Female; Fibrinolytic Agents; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Multicenter Studies as Topic; Myocardial Infarction; Platelet Aggregation Inhibitors; Prospective Studies; Prosthesis Failure; Sirolimus; Ticlopidine; Time Factors; Treatment Outcome; Withholding Treatment | 2014 |
Unanswered questions in patients with concurrent atrial fibrillation and acute coronary syndrome.
Topics: Acute Coronary Syndrome; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Comorbidity; Drug Therapy, Combination; Factor Xa Inhibitors; Humans; Morpholines; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Pyrazoles; Pyridones; Risk Assessment; Rivaroxaban; Stroke; Thiophenes; Thrombosis; Ticlopidine | 2014 |
Combining antiplatelet and antithrombotic therapy (triple therapy): what are the risks and benefits?
Topics: Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Risk Assessment; Ticlopidine; Warfarin | 2014 |
Platelet-reactivity tests identify patients at risk of secondary cardiovascular events: a systematic review and meta-analysis.
Topics: Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Risk Factors; Ticlopidine | 2014 |
Pharmacogenomics of oral antiplatelet drugs.
Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Humans; Meta-Analysis as Topic; Pharmacogenetics; Platelet Aggregation Inhibitors; Ticlopidine | 2014 |
Rationale and design of The Intracoronary Stenting and Antithrombotic Regimen-Testing of a six-week versus a six-month clopidogrel treatment Regimen In Patients with concomitant aspirin and oraL anticoagulant therapy following drug-Eluting stenting (ISAR-
Topics: Administration, Oral; Aspirin; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug-Eluting Stents; Follow-Up Studies; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Thrombolytic Therapy; Ticlopidine | 2014 |
Oral antiplatelet therapy for acute ischaemic stroke.
Topics: Aspirin; Brain Ischemia; Dipyridamole; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk; Stroke; Ticlopidine; Time-to-Treatment | 2014 |
Stroke: transient ischemic attack.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain; Clopidogrel; Diffusion Magnetic Resonance Imaging; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Risk Reduction Behavior; Stroke; Ticlopidine; Tomography, X-Ray Computed | 2014 |
Should P2Y12 inhibitors be given for 12 months in acute coronary syndrome?
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Humans; Myocardial Ischemia; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Randomized Controlled Trials as Topic; Stents; Ticlopidine; Time Factors | 2014 |
Efficacy and safety of cilostazol based triple antiplatelet treatment versus dual antiplatelet treatment in patients undergoing coronary stent implantation: an updated meta-analysis of the randomized controlled trials.
Topics: Aspirin; Brain Ischemia; Cilostazol; Clopidogrel; Drug Therapy, Combination; Female; Humans; Male; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stents; Stroke; Tetrazoles; Thrombosis; Ticlopidine | 2015 |
Front-loading with clopidogrel plus aspirin followed by dual antiplatelet therapy in the prevention of early stroke recurrence.
Topics: Animals; Aspirin; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Recurrence; Stroke; Ticlopidine | 2014 |
The pharmacogenetics of carboxylesterases: CES1 and CES2 genetic variants and their clinical effect.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antiviral Agents; Aspirin; Benzimidazoles; Camptothecin; Carboxylesterase; Carboxylic Ester Hydrolases; Central Nervous System Stimulants; Clopidogrel; Dabigatran; Factor Xa Inhibitors; Genotype; Humans; Imidazolidines; Irinotecan; Isoenzymes; Methylphenidate; Oseltamivir; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Pyridines; Ticlopidine | 2014 |
Intracerebral hemorrhage after pipeline embolization: Management of antiplatelet agents and the case for point-of-care testing--case reports and review of literature.
Topics: Aspirin; Cerebral Hemorrhage; Clinical Protocols; Clopidogrel; Drug Administration Schedule; Embolization, Therapeutic; Humans; Middle Aged; Platelet Aggregation Inhibitors; Platelet Transfusion; Receptors, Purinergic P2Y12; Ticlopidine | 2014 |
Systematic reviews and meta-analyses for more profitable strategies in peripheral artery disease.
Topics: Adenosine; Aspirin; Asymptomatic Diseases; Cilostazol; Clopidogrel; Fibrinolytic Agents; Humans; Intermittent Claudication; Ischemia; Lower Extremity; Meta-Analysis as Topic; Myocardial Infarction; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Primary Prevention; Review Literature as Topic; Secondary Prevention; Stroke; Tetrazoles; Thrombosis; Ticagrelor; Ticlopidine | 2014 |
Efficacy and safety of adding clopidogrel to aspirin on stroke prevention among high vascular risk patients: a meta-analysis of randomized controlled trials.
Topics: Aspirin; Clopidogrel; Hemorrhage; Humans; Randomized Controlled Trials as Topic; Risk; Safety; Stroke; Ticlopidine | 2014 |
[Antiplatelet drugs].
Topics: Acute Coronary Syndrome; Aspirin; Blood Platelets; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2014 |
[Antiplatelet therapy for secondary prevention of cerebral infarction].
Topics: Aspirin; Cerebral Infarction; Clopidogrel; Drug Therapy, Combination; Humans; Japan; Platelet Aggregation Inhibitors; Secondary Prevention; Ticlopidine | 2014 |
[Antiplatelet therapy in atherosclerosis of various localizations: acute and stable States].
Topics: Acute Coronary Syndrome; Aspirin; Atherosclerosis; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Humans; Platelet Aggregation Inhibitors; Risk Adjustment; Ticlopidine; Treatment Outcome | 2014 |
Decade in review--acute coronary syndromes: Successes and future objectives in acute coronary syndrome.
Topics: Acute Coronary Syndrome; Anticoagulants; Antithrombins; Aspirin; Clopidogrel; Hemorrhage; Humans; Myocardial Revascularization; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Ticlopidine | 2014 |
[Using ADP receptor antagonists in coronary heart disease and acute coronary syndrome].
Topics: Acute Coronary Syndrome; Adenosine; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Early Medical Intervention; General Practice; Guideline Adherence; Humans; Male; Middle Aged; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Secondary Prevention; Stents; Thiophenes; Ticagrelor; Ticlopidine | 2014 |
Managing antithrombotic therapy in patients with both atrial fibrillation and coronary heart disease.
Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Fibrinolytic Agents; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Stroke; Ticlopidine; Vitamin K; Warfarin | 2014 |
Triple therapy for atrial fibrillation and percutaneous coronary intervention: a contemporary review.
Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Humans; Percutaneous Coronary Intervention; Randomized Controlled Trials as Topic; Ticlopidine; Vitamin K | 2014 |
Dual versus single antiplatelet therapy in patients undergoing transcatheter aortic valve replacement: a systematic review and meta-analysis.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Time Factors; Transcatheter Aortic Valve Replacement | 2015 |
Management of acute coronary syndrome in the hospital: a focus on ACCF/AHA guideline updates to oral antiplatelet therapy.
Topics: Acute Coronary Syndrome; Adenosine; Age Factors; Aspirin; Body Weight; Clopidogrel; Humans; Myocardial Infarction; Piperazines; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Prasugrel Hydrochloride; Quality of Health Care; Randomized Controlled Trials as Topic; Thiophenes; Ticagrelor; Ticlopidine | 2014 |
Aspirin, clopidogrel, and the surgeon.
Topics: Aspirin; Cardiovascular Diseases; Cerebrovascular Disorders; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Postoperative Complications; Postoperative Hemorrhage; Practice Guidelines as Topic; Preoperative Care; Risk Assessment; Thienopyridines; Ticlopidine; Time Factors; Withholding Treatment | 2014 |
Resistance to antiplatelet drugs: what progress has been made?
Topics: Aspirin; Clopidogrel; Graft Occlusion, Vascular; Hemorrhage; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Precision Medicine; Purinergic P2Y Receptor Antagonists; Randomized Controlled Trials as Topic; Risk Factors; Stents; Thrombosis; Ticlopidine; Treatment Failure | 2014 |
Epidemiology, risk factors and management of cardiovascular diseases in IBD.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Clopidogrel; Endothelium, Vascular; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammatory Bowel Diseases; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine | 2015 |
[Added value of clopidogrel in cardiology and neurology].
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Risk Factors; Secondary Prevention; Stroke; Thrombosis; Ticlopidine | 2014 |
Effect of addition of clopidogrel to aspirin on subdural hematoma: meta-analysis of randomized clinical trials.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Atrial Fibrillation; Clopidogrel; Drug Therapy, Combination; Female; Hematoma, Subdural; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stroke, Lacunar; Ticlopidine | 2015 |
Comparative effectiveness review of antiplatelet agents in peripheral artery disease.
Topics: Aspirin; Clopidogrel; Comparative Effectiveness Research; Drug Therapy, Combination; Humans; Patient Safety; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Risk Assessment; Risk Factors; Ticlopidine; Treatment Outcome | 2014 |
Reversing the effects of antiplatelet agents in the setting of intracranial hemorrhage: a look at the literature.
Topics: Aspirin; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Factor VIIa; Humans; Intracranial Hemorrhages; Platelet Aggregation Inhibitors; Platelet Transfusion; Recombinant Proteins; Ticlopidine; Treatment Outcome | 2015 |
Use of antiplatelet drugs after cardiac operations.
Topics: Aspirin; Clopidogrel; Coronary Artery Bypass; Drug Administration Schedule; Drug Therapy, Combination; Graft Occlusion, Vascular; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome; Vascular Patency | 2014 |
Aspirin plus clopidogrel as secondary prevention after stroke or transient ischemic attack: a systematic review and meta-analysis.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Recurrence; Secondary Prevention; Stroke; Ticlopidine | 2015 |
Management of low-dose aspirin and clopidogrel in clinical practice: a gastrointestinal perspective.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Gastrointestinal Diseases; Helicobacter Infections; Helicobacter pylori; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Risk Factors; Ticlopidine | 2015 |
Meta-analysis appraising high maintenance dose clopidogrel in patients who underwent percutaneous coronary intervention with and without high on-clopidogrel platelet reactivity.
Topics: Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Maintenance Chemotherapy; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine | 2015 |
Prasugrel hydrochloride for the treatment of acute coronary syndromes.
Topics: Acute Coronary Syndrome; Animals; Aspirin; Clinical Trials, Phase III as Topic; Clopidogrel; Drug Therapy, Combination; Humans; Percutaneous Coronary Intervention; Piperazines; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Randomized Controlled Trials as Topic; Thiophenes; Ticlopidine | 2015 |
[Anticoagulant therapy in secondary prevention of coronary events].
Topics: Acute Coronary Syndrome; Administration, Oral; Anticoagulants; Aspirin; Benzimidazoles; beta-Alanine; Clinical Trials as Topic; Clopidogrel; Dabigatran; Hemorrhage; Humans; Morpholines; Myocardial Infarction; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Pyrazoles; Pyridones; Rivaroxaban; Secondary Prevention; Thiophenes; Ticlopidine; Warfarin | 2014 |
Dual antiplatelet therapy for coronary artery disease.
Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2015 |
Clinical evidence for oral antiplatelet therapy in acute coronary syndromes.
Topics: Acute Coronary Syndrome; Adenosine; Administration, Oral; Aspirin; Clopidogrel; Coronary Artery Bypass; Drug Therapy, Combination; Humans; Intraoperative Care; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Precision Medicine; Thiophenes; Ticagrelor; Ticlopidine; Time Factors; Treatment Outcome | 2015 |
Meta-analysis of randomized controlled trials and adjusted observational results of use of clopidogrel, aspirin, and oral anticoagulants in patients undergoing percutaneous coronary intervention.
Topics: Administration, Oral; Anticoagulants; Aspirin; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Myocardial Ischemia; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stents; Ticlopidine; Treatment Outcome | 2015 |
Antiplatelet drug resistance: Molecular insights and clinical implications.
Topics: Aspirin; Clopidogrel; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2015 |
P2Y12 receptor inhibitors for secondary prevention of ischemic stroke.
Topics: Aspirin; Brain Ischemia; Clopidogrel; Hemorrhage; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Secondary Prevention; Stroke; Ticlopidine | 2015 |
Comparison of Dual-antiplatelet Therapy to Mono-antiplatelet Therapy After Transcatheter Aortic Valve Implantation: Systematic Review and Meta-analysis.
Topics: Aged; Aged, 80 and over; Aortic Valve Stenosis; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Postoperative Care; Postoperative Complications; Prognosis; Randomized Controlled Trials as Topic; Risk Assessment; Stroke; Survival Analysis; Ticlopidine; Transcatheter Aortic Valve Replacement; Treatment Outcome; Ultrasonography | 2015 |
Thrombocytopenia in acute coronary syndromes: etiologies and proposed management.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Therapy, Combination; Electrocardiography; Enzyme-Linked Immunosorbent Assay; Eptifibatide; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Peptides; Platelet Aggregation Inhibitors; Platelet Count; Platelet Transfusion; Risk Assessment; Thrombocytopenia; Ticlopidine; Treatment Outcome | 2015 |
Dual Antiplatelet Therapy After Coronary Artery Bypass Grafting in the Setting of Acute Coronary Syndrome.
Topics: Acute Coronary Syndrome; Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Artery Bypass; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine; Treatment Outcome | 2015 |
Antiplatelet therapy following transcatheter aortic valve implantation.
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Aortic Valve Stenosis; Aspirin; Cardiac Catheterization; Clopidogrel; Drug Therapy, Combination; Female; Heart Valve Prosthesis Implantation; Hemorrhage; Humans; Male; Odds Ratio; Platelet Aggregation Inhibitors; Risk Assessment; Risk Factors; Stroke; Ticlopidine; Time Factors; Treatment Outcome | 2015 |
Edoxaban versus placebo, aspirin, or aspirin plus clopidogrel for stroke prevention in atrial fibrillation. An indirect comparison analysis.
Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Brain Ischemia; Cerebral Hemorrhage; Clopidogrel; Drug Synergism; Drug Therapy, Combination; Embolism; Factor Xa Inhibitors; Humans; Mortality; Numbers Needed To Treat; Observational Studies as Topic; Platelet Aggregation Inhibitors; Pyridines; Randomized Controlled Trials as Topic; Risk; Risk Assessment; Stroke; Thiazoles; Thrombophilia; Ticlopidine; Vitamin K | 2015 |
New-onset atrial fibrillation after recent coronary stenting: Warfarin or non-vitamin K-antagonist oral anticoagulants to be added to aspirin and clopidogrel? A viewpoint.
Topics: Anticoagulants; Antithrombins; Aspirin; Atrial Fibrillation; Clopidogrel; Dabigatran; Drug Combinations; Factor Xa Inhibitors; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Pyrazoles; Pyridones; Stents; Thrombosis; Ticlopidine; Warfarin | 2015 |
Dual Antiplatelet Therapy of Clopidogrel and Aspirin in Secondary Prevention of Ischemic Stroke: Evidence and Indications.
Topics: Antiplatyhelmintic Agents; Aspirin; Brain Ischemia; Clopidogrel; Evidence-Based Medicine; Humans; Stroke; Ticlopidine | 2015 |
Ticagrelor, prasugrel, or clopidogrel in ST-segment elevation myocardial infarction: which one to choose?
Topics: Adenosine; Aspirin; Clopidogrel; Hemorrhage; Humans; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Randomized Controlled Trials as Topic; Ticagrelor; Ticlopidine; Treatment Outcome | 2015 |
Trends in pharmacological therapy following an acute coronary syndrome in Portugal: a systematic review.
Topics: Acute Coronary Syndrome; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Cardiovascular Agents; Clopidogrel; Hospitalization; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Secondary Prevention; Ticlopidine | 2016 |
Clopidogrel and Aspirin versus Aspirin Alone for Stroke Prevention: A Meta-Analysis.
Topics: Aspirin; Clopidogrel; Female; Hemorrhage; Humans; Male; Stroke; Ticlopidine | 2015 |
Antiplatelet therapies for secondary stroke prevention: an update on clinical and cost-effectiveness.
Topics: Aspirin; Clopidogrel; Cost-Benefit Analysis; Dipyridamole; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Secondary Prevention; Stroke; Ticlopidine | 2015 |
Antiplatelet therapy in acute coronary syndromes.
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Clopidogrel; Hemorrhage; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Receptor, PAR-1; Receptors, Purinergic P2Y12; Ticagrelor; Ticlopidine | 2015 |
Dual antiplatelet therapy with clopidogrel and aspirin for secondary stroke prevention.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Evidence-Based Medicine; Gastrointestinal Hemorrhage; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Public Health; Secondary Prevention; Stroke; Ticlopidine | 2015 |
Impact of greater than 12-month dual antiplatelet therapy duration on mortality: Drug-specific or a class-effect? A meta-analysis.
Topics: Aspirin; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Humans; Mortality; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Ticlopidine; Time Factors | 2015 |
Drug-drug interactions between clopidogrel and novel cardiovascular drugs.
Topics: Animals; Aspirin; Cardiovascular Agents; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Platelet Function Tests; Proton Pump Inhibitors; Ticlopidine | 2015 |
Recurrent acute coronary syndrome and restenosis after percutaneous coronary intervention in a patient with idiopathic thrombocytopenic purpura: a case report and literature review.
Topics: Acute Coronary Syndrome; Aged; Anticoagulants; Aspirin; Clopidogrel; Coronary Angiography; Drug-Eluting Stents; Heparin; Humans; Male; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Purpura, Thrombocytopenic, Idiopathic; Recurrence; Ticlopidine | 2015 |
Vorapaxar for reduction of thrombotic cardiovascular events in myocardial infarction and peripheral artery disease.
Topics: Aspirin; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Half-Life; Hemorrhage; Humans; Lactones; Myocardial Infarction; Myocardial Ischemia; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Pyridines; Randomized Controlled Trials as Topic; Receptor, PAR-1; Secondary Prevention; Stroke; Thrombosis; Ticlopidine | 2015 |
Dual antiplatelet therapy with clopidogrel and aspirin after ischemic stroke: A review of the evidence.
Topics: Aspirin; Atherosclerosis; Blood Platelets; Clopidogrel; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Multicenter Studies as Topic; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Secondary Prevention; Severity of Illness Index; Stroke; Ticlopidine; Time Factors | 2015 |
Comparing the effectiveness and safety between triple antiplatelet therapy and dual antiplatelet therapy in type 2 diabetes mellitus patients after coronary stents implantation: a systematic review and meta-analysis of randomized controlled trials.
Topics: Acute Coronary Syndrome; Aspirin; Cilostazol; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Stents; Tetrazoles; Thrombosis; Ticlopidine | 2015 |
Solid cancers after antiplatelet therapy: Confirmations, controversies, and challenges.
Topics: Adenosine; Animals; Anticarcinogenic Agents; Aspirin; Blood Platelets; Carcinogenicity Tests; Clopidogrel; Colonic Neoplasms; Drug Therapy, Combination; Female; Humans; Lactones; Male; Mice; Multicenter Studies as Topic; Neoplasm Metastasis; Neoplasms; Neoplasms, Experimental; Neoplastic Cells, Circulating; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Pyridines; Randomized Controlled Trials as Topic; Rivaroxaban; Sex Factors; Species Specificity; Ticagrelor; Ticlopidine; Time Factors | 2015 |
Antiplatelet Agents in Cardiology: A Report on Aspirin, Clopidogrel, Prasugrel, and Ticagrelor.
Topics: Adenosine; Aspirin; Cardiovascular Diseases; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Ticagrelor; Ticlopidine; Transcatheter Aortic Valve Replacement | 2016 |
[Meta-analysis on the efficacy and adverse events of aspirin plus clopidogrel versus aspirin-monotherapy in patients with ischemic stroke or transient ischemic attack].
Topics: Aspirin; Clopidogrel; Databases, Factual; Drug Therapy, Combination; Hemorrhage; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Recurrence; Risk; Stroke; Ticlopidine; Treatment Outcome | 2015 |
Long-term antiplatelet therapy following myocardial infarction: implications of PEGASUS-TIMI 54.
Topics: Adenosine; Aspirin; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Hemorrhage; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Purinergic P2Y Receptor Antagonists; Randomized Controlled Trials as Topic; Recurrence; Risk Assessment; Risk Factors; Secondary Prevention; Ticagrelor; Ticlopidine; Time Factors; Treatment Outcome | 2016 |
Vorapaxar and diplopia: Possible off-target PAR-receptor mismodulation.
Topics: Animals; Aspirin; Clopidogrel; Diplopia; Drug Approval; Eye; Humans; Lactones; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Pyridines; Randomized Controlled Trials as Topic; Receptor, PAR-1; Receptors, Proteinase-Activated; Ticlopidine; United States; United States Food and Drug Administration | 2016 |
Exodontia in dual antiplatelet therapy: the evidence.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Oral Surgical Procedures; Platelet Aggregation Inhibitors; Ticlopidine | 2016 |
Perioperative Management to Reduce Cardiovascular Events.
Topics: Adrenergic beta-Antagonists; Aged; Anesthesia; Anticoagulants; Arthroplasty, Replacement, Knee; Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Contraindications; Coronary Disease; Disease Susceptibility; Heparin, Low-Molecular-Weight; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Male; Perioperative Care; Postoperative Complications; Postoperative Hemorrhage; Preanesthetic Medication; Risk Factors; Risk Reduction Behavior; Stress, Physiological; Surgical Procedures, Operative; Thrombophilia; Ticlopidine | 2016 |
Antiplatelet regimens in the long-term secondary prevention of transient ischaemic attack and ischaemic stroke: an updated network meta-analysis.
Topics: Aspirin; Cilostazol; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Hemorrhage; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Secondary Prevention; Stroke; Tetrazoles; Ticlopidine | 2016 |
Dual antiplatelet therapy after stroke or transient ischaemic attack - how long to treat? The duration of aspirin plus clopidogrel in stroke or transient ischaemic attack: a systematic review and meta-analysis.
Topics: Aspirin; Clopidogrel; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Recurrence; Secondary Prevention; Stroke; Ticlopidine; Time Factors | 2016 |
The pharmacodynamics of antiplatelet compounds in thrombosis treatment.
Topics: Acute Coronary Syndrome; Animals; Aspirin; Blood Platelets; Clopidogrel; Drug Design; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Thrombosis; Ticlopidine | 2016 |
What is the optimal duration of dual antiplatelet therapy after percutaneous coronary intervention with drug-eluting stent implantation?
Topics: Aspirin; Clopidogrel; Drug Administration Schedule; Drug-Eluting Stents; Hemorrhage; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Thrombosis; Ticlopidine; Time Factors | 2016 |
Systematic review of the clinical impact of dual antiplatelet therapy discontinuation after acute coronary syndromes.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Prognosis; Ticlopidine; Time Factors; Withholding Treatment | 2017 |
Individualizing Duration of Dual Antiplatelet Therapy After Acute Coronary Syndrome or Percutaneous Coronary Intervention.
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Aspirin; Drug Administration Schedule; Female; Hemorrhage; Humans; Male; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Precision Medicine; Purinergic P2Y Receptor Antagonists; Ticlopidine | 2016 |
Comparison of current platelet functional tests for the assessment of aspirin and clopidogrel response. A review of the literature.
Topics: Aspirin; Blood Platelets; Clopidogrel; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2016 |
Bleeding Risk with Long-Term Low-Dose Aspirin: A Systematic Review of Observational Studies.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Clopidogrel; Databases, Factual; Gastrointestinal Hemorrhage; Humans; Incidence; Intracranial Hemorrhages; Observational Studies as Topic; Odds Ratio; Risk; Ticlopidine | 2016 |
Dual antiplatelet therapy for secondary stroke prevention: Use of clopidogrel and acetylsalicylic acid after noncardioembolic ischemic stroke.
Topics: Aged, 80 and over; Aspirin; Cerebral Infarction; Clopidogrel; Drug Therapy, Combination; Female; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Secondary Prevention; Ticlopidine; Tomography, X-Ray Computed; Treatment Outcome | 2016 |
A systematic review of anti-thrombotic therapy in epistaxis.
Topics: Anticoagulants; Antifibrinolytic Agents; Aspirin; Clopidogrel; Dabigatran; Disease Management; Epistaxis; Humans; Platelet Aggregation Inhibitors; Pyrazoles; Pyridones; Risk Assessment; Rivaroxaban; Ticlopidine; Tranexamic Acid; Warfarin | 2016 |
Aspirin, Plavix, and Other Antiplatelet Medications: What the Oral and Maxillofacial Surgeon Needs to Know.
Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Humans; Medication Therapy Management; Oral Surgical Procedures; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Ticlopidine | 2016 |
Proton Pump Inhibitors in Cardiovascular Disease: Drug Interactions with Antiplatelet Drugs.
Topics: Adenosine; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Administration Schedule; Drug Dosage Calculations; Drug Interactions; Esomeprazole; Gastrointestinal Hemorrhage; Gene Expression; Humans; Hydrogen-Ion Concentration; Peptic Ulcer; Prasugrel Hydrochloride; Proton Pump Inhibitors; Purinergic Antagonists; Receptors, Purinergic P2Y12; Ticagrelor; Ticlopidine | 2017 |
[Direct oral anticoagulants in cardiology].
Topics: Administration, Oral; Anticoagulants; Aspirin; Cardiology; Cardiovascular Diseases; Clopidogrel; Fibrinolytic Agents; Heparin; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Warfarin | 2016 |
Immature Platelets: Clinical Relevance and Research Perspectives.
Topics: Acute Coronary Syndrome; Aspirin; Blood Platelets; Clopidogrel; Humans; Megakaryocytes; RNA, Messenger; Ticlopidine | 2016 |
Prasugrel hydrochloride for the treatment of acute coronary syndrome patients.
Topics: Acute Coronary Syndrome; Administration, Oral; Aspirin; Blood Platelets; Clopidogrel; Hemorrhage; Humans; Percutaneous Coronary Intervention; Platelet Activation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thrombosis; Ticlopidine | 2016 |
Cardiovascular pharmacogenetics: a promise for genomically-guided therapy and personalized medicine.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Genetic Predisposition to Disease; Genetic Variation; Genome, Human; Genomics; Humans; Pharmacogenetics; Precision Medicine; Ticlopidine; Warfarin | 2017 |
Pharmacokinetics and pharmacodynamics of ticagrelor in the treatment of cardiac ischemia.
Topics: Acute Coronary Syndrome; Adenosine; Animals; Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Myocardial Ischemia; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Ticagrelor; Ticlopidine; Time Factors | 2016 |
Current controversies in the use of aspirin and ticagrelor for the treatment of thrombotic events.
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Thrombosis; Ticagrelor; Ticlopidine | 2016 |
Risk and Benefits of Triple Therapy in Patients Undergoing Coronary Stent Implantation Requiring Oral Anticoagulation: A Meta-Analysis of 16 Studies.
Topics: Anticoagulants; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy; Fibrinolytic Agents; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Risk; Stents; Ticlopidine; Warfarin | 2016 |
A critical reappraisal of aspirin for secondary prevention in patients with ischemic heart disease.
Topics: Adenosine; Antithrombins; Aspirin; Clopidogrel; Drug Therapy, Combination; Evidence-Based Medicine; Factor Xa Inhibitors; Hemorrhage; History, 20th Century; History, 21st Century; History, Ancient; Humans; Myocardial Ischemia; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Secondary Prevention; Ticagrelor; Ticlopidine | 2016 |
Optimal pediatric dosing of anti-platelet agents for pipeline stent embolization -a case report and review of the literature.
Topics: Adolescent; Aspirin; Bone Neoplasms; Cerebral Hemorrhage; Clopidogrel; Embolization, Therapeutic; Female; Humans; Osteoblastoma; Platelet Aggregation Inhibitors; Ticlopidine | 2017 |
Spontaneous coronary artery dissection: Case report and review of the literature.
Topics: Acute Coronary Syndrome; Adrenergic beta-1 Receptor Antagonists; Adult; Aspirin; Atorvastatin; Clopidogrel; Coronary Angiography; Coronary Vessel Anomalies; Echocardiography; Electrocardiography; Female; Humans; Metoprolol; Platelet Aggregation Inhibitors; Ticlopidine; Vascular Diseases | 2016 |
East Asian perspective on the interaction between proton pump inhibitors and clopidogrel.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anticoagulants; Asia, Eastern; Asian People; Aspirin; Clopidogrel; Cytochrome P-450 CYP2C19; Dexlansoprazole; Drug Interactions; Drug Therapy, Combination; Gastroesophageal Reflux; Gastrointestinal Hemorrhage; Humans; Isoenzymes; Pantoprazole; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Proton Pump Inhibitors; Rabeprazole; Ticlopidine | 2017 |
Cancer Event Rate and Mortality with Thienopyridines: A Systematic Review and Meta-Analysis.
Topics: Aspirin; Clopidogrel; Humans; Incidence; Neoplasms; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Randomized Controlled Trials as Topic; Risk; Thienopyridines; Ticlopidine | 2017 |
Three, six, or twelve months of dual antiplatelet therapy after DES implantation in patients with or without acute coronary syndromes: an individual patient data pairwise and network meta-analysis of six randomized trials and 11 473 patients.
Topics: Acute Coronary Syndrome; Analysis of Variance; Aspirin; Blood Vessel Prosthesis Implantation; Clopidogrel; Coronary Artery Disease; Death, Sudden, Cardiac; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Female; Graft Occlusion, Vascular; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Revascularization; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Randomized Controlled Trials as Topic; Risk Assessment; Stroke; Ticlopidine; Treatment Outcome | 2017 |
Oral antiplatelet agents for the management of acute coronary syndromes: A review for nurses and allied healthcare professionals.
Topics: Acute Coronary Syndrome; Adenosine; Administration, Oral; Arylsulfonates; Aspirin; Clopidogrel; Disease Management; Humans; Nurse Practitioners; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Ticagrelor; Ticlopidine | 2017 |
Monitoring Antiplatelet Therapy.
Topics: Aspirin; Blood Platelets; Clopidogrel; Drug Monitoring; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Purinergic P2Y Receptor Antagonists; Reproducibility of Results; Thrombosis; Ticlopidine | 2017 |
Derivation and validation of the predicting bleeding complications in patients undergoing stent implantation and subsequent dual antiplatelet therapy (PRECISE-DAPT) score: a pooled analysis of individual-patient datasets from clinical trials.
Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Hemorrhage; Humans; Kaplan-Meier Estimate; Middle Aged; Multicenter Studies as Topic; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Randomized Controlled Trials as Topic; Risk Assessment; Stents; Ticlopidine; Treatment Outcome | 2017 |
Bleeding risk of antiplatelet drugs compared with oral anticoagulants in older patients with atrial fibrillation: a systematic review and meta-analysis.
Topics: Administration, Oral; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Cohort Studies; Female; Hemorrhage; Humans; Intracranial Hemorrhages; Male; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk; Stroke; Ticlopidine; Treatment Outcome; Vitamin K; Warfarin | 2017 |
High on treatment platelet reactivity to aspirin and clopidogrel in ischemic stroke: A systematic review and meta-analysis.
Topics: Aspirin; Blood Platelets; Brain Ischemia; Clopidogrel; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2017 |
Antiplatelet treatments: recent evidence from randomized controlled trials.
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Atherosclerosis; Blood Platelets; Humans; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Randomized Controlled Trials as Topic; Ticagrelor; Ticlopidine | 2017 |
A Meta-analysis of the Impact of Aspirin, Clopidogrel, and Dual Antiplatelet Therapy on Bleeding Complications in Noncardiac Surgery.
Topics: Aspirin; Blood Loss, Surgical; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Risk Factors; Surgical Procedures, Operative; Ticlopidine | 2018 |
Antithrombotic strategies for preventing long-term major adverse cardiovascular events in patients with non-valvular atrial fibrillation who undergo percutaneous coronary intervention.
Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Hemorrhage; Humans; Myocardial Ischemia; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Recurrence; Ticlopidine | 2017 |
[Management of the bleeding risk associated with antiplatelet agents].
Topics: Adenosine; Aspirin; Clopidogrel; Drug-Related Side Effects and Adverse Reactions; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Risk Factors; Ticagrelor; Ticlopidine | 2017 |
Antiplatelet Therapy, Platelet Function Testing, and Bleeding Complications in Cardiac Surgery Patients.
Topics: Aspirin; Blood Platelets; Cardiac Surgical Procedures; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Postoperative Complications; Ticlopidine | 2017 |
How I use laboratory monitoring of antiplatelet therapy.
Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Drug Monitoring; Humans; Male; Middle Aged; Molecular Targeted Therapy; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2017 |
The Efficacy and Safety of 3 Types of Interventions for Stroke Prevention in Patients With Cardiovascular and Cerebrovascular Diseases: A Network Meta-analysis.
Topics: Anticoagulants; Aspirin; Bayes Theorem; Cardiovascular Diseases; Clopidogrel; Dabigatran; Dipyridamole; Hemorrhage; Humans; Odds Ratio; Pyrazoles; Pyridines; Pyridones; Randomized Controlled Trials as Topic; Thiazoles; Ticlopidine; Treatment Outcome; Warfarin | 2017 |
[Antiplatelet agents and transfusion].
Topics: Adenosine; Antidotes; Aspirin; Clopidogrel; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Platelet Transfusion; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Risk; Ticagrelor; Ticlopidine | 2017 |
[Impact of different antithrombotic therapy strategy on prognosis in coronary heart disease patients combining with atrial fibrillation: a meta analysis].
Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Disease; Fibrinolytic Agents; Hemorrhage; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prognosis; Randomized Controlled Trials as Topic; Stroke; Ticlopidine; Warfarin | 2017 |
Duration of dual antiplatelet therapy after coronary stent insertion: Does the benefit of extended therapy outweigh the risk?
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Male; Meta-Analysis as Topic; Middle Aged; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine; Time Factors | 2016 |
Antiplatelet Regimen for Patients With Breakthrough Strokes While on Aspirin: A Systematic Review and Meta-Analysis.
Topics: Adenosine; Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Proportional Hazards Models; Recurrence; Secondary Prevention; Stroke; Ticagrelor; Ticlopidine; Treatment Failure | 2017 |
Dual Versus Single Antiplatelet Regimen With or Without Anticoagulation in Transcatheter Aortic Valve Replacement: Indirect Comparison and Meta-analysis.
Topics: Anticoagulants; Aortic Valve; Aortic Valve Stenosis; Aspirin; Clopidogrel; Drug Therapy, Combination; Heart Valve Prosthesis; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Transcatheter Aortic Valve Replacement; Treatment Outcome | 2018 |
A Primer on Bleeding Risk and Management Strategies of Newer Oral Anti Platelet Agents in Cardiovascular Disease.
Topics: Adenosine; Administration, Oral; Aspirin; Cardiovascular Diseases; Clopidogrel; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Risk Factors; Thrombosis; Ticagrelor; Ticlopidine | 2016 |
Risk of Early Adverse Events After Clopidogrel Discontinuation in Patients Undergoing Short-Term Dual Antiplatelet Therapy: An Individual Participant Data Analysis.
Topics: Aged; Aspirin; Clopidogrel; Coronary Restenosis; Coronary Thrombosis; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proportional Hazards Models; Purinergic P2Y Receptor Antagonists; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Ticlopidine; Time Factors; Treatment Outcome | 2017 |
Perioperative management of antithrombotic therapy in patients receiving cardiovascular implantable electronic devices: a network meta-analysis.
Topics: Administration, Oral; Anticoagulants; Aspirin; Cardiac Resynchronization Therapy Devices; Cause of Death; Clopidogrel; Defibrillators, Implantable; Evidence-Based Medicine; Female; Humans; Injections, Subcutaneous; Male; Network Meta-Analysis; Observational Studies as Topic; Pacemaker, Artificial; Perioperative Care; Prognosis; Risk Assessment; Survival Analysis; Thromboembolism; Ticlopidine; Treatment Outcome; Warfarin | 2017 |
Review of aspirin and clopidogrel resistance in peripheral arterial disease.
Topics: Aspirin; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Resistance; Genotype; Humans; Peripheral Arterial Disease; Pharmacogenomic Variants; Phenotype; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Risk Factors; Ticlopidine; Treatment Outcome | 2017 |
International Expert Consensus on Switching Platelet P2Y
Topics: Administration, Intravenous; Administration, Oral; Aspirin; Clopidogrel; Consensus; Drug Substitution; Humans; Internationality; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Ticlopidine | 2017 |
Recurrent Ischemic Stroke: Strategies for Prevention.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Humans; Ischemic Attack, Transient; Male; Platelet Aggregation Inhibitors; Recurrence; Risk Factors; Secondary Prevention; Stroke; Ticlopidine; United States | 2017 |
The role of prasugrel in the management of acute coronary syndromes: a systematic review.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thrombosis; Ticlopidine | 2017 |
Clopidogrel plus aspirin versus aspirin alone for preventing cardiovascular events.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine | 2017 |
Influence of proton pump inhibitors on clinical outcomes in coronary heart disease patients receiving aspirin and clopidogrel: A meta-analysis.
Topics: Aspirin; Clopidogrel; Coronary Disease; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine | 2018 |
Aspirin plus dipyridamole has the highest surface under the cumulative ranking curves (SUCRA) values in terms of mortality, intracranial hemorrhage, and adverse event rate among 7 drug therapies in the treatment of cerebral infarction.
Topics: Aspirin; Cerebral Infarction; Cilostazol; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Hematologic Agents; Humans; Intracranial Hemorrhages; Tetrazoles; Ticlopidine; Warfarin | 2018 |
Clinical utility of remote platelet function measurement using P-selectin: assessment of aspirin, clopidogrel, and prasugrel and bleeding disorders.
Topics: Aspirin; Blood Platelets; Clopidogrel; Female; Hemorrhage; Humans; Male; P-Selectin; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Ticlopidine | 2018 |
Dual and triple antithrombotic therapies: current patterns of practice and controversies.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Patient Safety; Percutaneous Coronary Intervention; Ticlopidine; Treatment Outcome; Warfarin | 2018 |
Efficacy and safety of dual antiplatelet therapy in the elderly for stroke prevention: a systematic review and meta-analysis.
Topics: Aged; Aspirin; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Intracranial Hemorrhages; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2018 |
[2017 Update on dual antiplatelet therapy: what's new?]
Topics: Advisory Committees; Aged; Aspirin; Coronary Angiography; Coronary Stenosis; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Italy; Male; Middle Aged; Platelet Aggregation Inhibitors; Prognosis; Severity of Illness Index; Survival Rate; Ticlopidine; Treatment Outcome | 2018 |
Continuation versus discontinuation of antiplatelet therapy for bleeding and ischaemic events in adults undergoing non-cardiac surgery.
Topics: Adult; Aspirin; Cause of Death; Clopidogrel; Elective Surgical Procedures; Hemorrhage; Humans; Ischemia; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine; Withholding Treatment | 2018 |
[Anti-Thrombotic Treatment of Patients with Peripheral Artery Disease (PAD)].
Topics: Administration, Oral; Anticoagulants; Aspirin; Blood Vessel Prosthesis Implantation; Clopidogrel; Drug Therapy, Combination; Fibrinolytic Agents; Germany; Guideline Adherence; Humans; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Postoperative Care; Rivaroxaban; Secondary Prevention; Ticlopidine; Veins | 2018 |
Triple therapy: worth the risk?
Topics: Anticoagulants; Aspirin; Clopidogrel; Drug Synergism; Drug Therapy, Combination; Factor Xa Inhibitors; Hemorrhage; Humans; Mortality; Multicenter Studies as Topic; Myocardial Infarction; Platelet Aggregation Inhibitors; Postoperative Complications; Purinergic P2Y Receptor Antagonists; Randomized Controlled Trials as Topic; Rivaroxaban; Stents; Stroke; Thrombophilia; Ticlopidine | 2018 |
[TREATMENT WITH DUAL ANTIPLATELET THERAPY FOR SECONDARY PREVENTION OF STROKE - PROS AND CONS].
Topics: Aspirin; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Secondary Prevention; Stroke; Ticlopidine | 2018 |
Monotherapy with a P2Y
Topics: Aged; Aspirin; Atherosclerosis; Cerebrovascular Disorders; Clopidogrel; Coronary Disease; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Randomized Controlled Trials as Topic; Risk Assessment; Secondary Prevention; Stroke; Ticagrelor; Ticlopidine | 2020 |
Navigating Antiplatelet Treatment Options for Stroke: Evidence-Based and Pragmatic Strategies.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Ischemic Stroke; Platelet Aggregation Inhibitors; Stroke; Ticagrelor; Ticlopidine | 2022 |
Hypoglycemia as a potential risk for patients taking clopidogrel: A systematic review and meta-analysis.
Topics: Aged; Aspirin; Clopidogrel; Humans; Hypoglycemia; Platelet Aggregation Inhibitors; Ticlopidine | 2023 |
873 trial(s) available for ticlopidine and aspirin
| Article | Year |
|---|---|
Antiplatelet drugs and generation of thrombin in clotting blood.
Topics: Adult; Aspirin; Blood Coagulation; Female; Fibrinopeptide A; Humans; In Vitro Techniques; Indomethacin; Kinetics; Male; Mathematics; Methacrylates; Middle Aged; Models, Biological; Platelet Aggregation Inhibitors; Skin; Thrombin; Thromboxane-A Synthase; Ticlopidine | 1992 |
Ticlopidine versus aspirin for the prevention of recurrent stroke. Analysis of patients with minor stroke from the Ticlopidine Aspirin Stroke Study.
Topics: Adult; Aspirin; Cerebrovascular Disorders; Diarrhea; Double-Blind Method; Female; Humans; Male; Middle Aged; Neutropenia; Recurrence; Ticlopidine | 1992 |
Bleeding time and antiplatelet agents in normal volunteers.
Topics: Adolescent; Adult; Aspirin; Bleeding Time; Female; Humans; Isoindoles; Male; Phenylbutyrates; Platelet Aggregation Inhibitors; Reference Values; Ticlopidine | 1992 |
Ticlopidine, a new anti-thrombotic drug.
Topics: Aspirin; Dipyridamole; Humans; Intracranial Embolism and Thrombosis; Long-Term Care; Recurrence; Ticlopidine | 1991 |
[Anticoagulant or antiplatelet aggregation treatment after aortocoronary bypass].
Topics: Anticoagulants; Aspirin; Coronary Artery Bypass; Dipyridamole; Graft Occlusion, Vascular; Humans; Meta-Analysis as Topic; Platelet Aggregation Inhibitors; Sulfinpyrazone; Ticlopidine; Vitamin K | 1991 |
Epidemiology of and stroke-preventive strategies for atherothromboembolic brain infarction in the elderly.
Topics: Aged; Anticoagulants; Arteriosclerosis; Aspirin; Cerebral Infarction; Cerebrovascular Disorders; Female; Humans; Intracranial Embolism and Thrombosis; Ischemic Attack, Transient; Male; Middle Aged; Pentoxifylline; Risk Factors; Ticlopidine | 1991 |
Effect of ticlopidine and aspirin on platelet ionized calcium in ischemic stroke.
Topics: Aspirin; Blood Platelets; Brain Ischemia; Calcium; Collagen; Humans; In Vitro Techniques; Platelet Activating Factor; Thrombin; Ticlopidine | 1991 |
Ticlopidine in unstable angina. A more expensive aspirin?
Topics: Angina Pectoris; Angina, Unstable; Aspirin; Clinical Trials as Topic; Cost-Benefit Analysis; Cyclooxygenase Inhibitors; Humans; Neutropenia; Ticlopidine | 1990 |
Ticlopidine, a new antithrombotic drug: but is it better than aspirin for longterm use?
Topics: Aspirin; Cerebrovascular Disorders; Humans; Ischemic Attack, Transient; Myocardial Infarction; Randomized Controlled Trials as Topic; Ticlopidine | 1990 |
Ticlopidine in unstable angina.
Topics: Angina, Unstable; Aspirin; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 1990 |
The "trials" of a long-term clinical trial: the Ticlopidine Aspirin Stroke Study and the Canadian-American Ticlopidine Study.
Topics: Aspirin; Canada; Cerebrovascular Disorders; Humans; Legislation, Drug; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Research Design; Sampling Studies; Therapeutic Equivalency; Ticlopidine; United States | 1989 |
A randomized trial comparing ticlopidine hydrochloride with aspirin for the prevention of stroke in high-risk patients. Ticlopidine Aspirin Stroke Study Group.
Topics: Aspirin; Cerebrovascular Disorders; Female; Follow-Up Studies; Humans; Ischemic Attack, Transient; Male; Middle Aged; Random Allocation; Retina; Ticlopidine | 1989 |
[Platelet function inhibitors in peripheral arteriopathies].
Topics: Adrenal Cortex Hormones; Adrenergic alpha-Antagonists; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Arteriosclerosis Obliterans; Aspirin; Blood Platelets; Calcium Channel Blockers; Clinical Trials as Topic; Cyclic AMP; Dipyridamole; Extremities; Heparin; Humans; Imidazoles; Prostaglandins; Prostanoic Acids; Pyrazoles; Pyrazolones; Quinacrine; Thiophenes; Thromboembolism; Thrombosis; Ticlopidine; Vascular Diseases | 1986 |
Comparison of the inhibitory effects of cilostazol, acetylsalicylic acid and ticlopidine on platelet functions ex vivo. Randomized, double-blind cross-over study.
Topics: Aged; Aspirin; Azoles; beta-Thromboglobulin; Blood Platelets; Cilostazol; Double-Blind Method; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Factor 4; Random Allocation; Tetrazoles; Ticlopidine | 1987 |
Mode of action of currently used antiplatelet drugs.
Topics: Aspirin; Blood Platelets; Blood Vessels; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Humans; Platelet Aggregation; Platelet Membrane Glycoproteins; Sulfinpyrazone; Ticlopidine | 1986 |
Clinical trials evaluating platelet-modifying drugs in patients with atherosclerotic cardiovascular disease and thrombosis.
Topics: Anticoagulants; Aspirin; Blood Platelets; Blood Vessel Prosthesis; Cardiovascular Diseases; Clinical Trials as Topic; Dipyridamole; Double-Blind Method; Female; Glomerulonephritis; Graft Occlusion, Vascular; Heart Valve Prosthesis; Humans; Ischemic Attack, Transient; Male; Myocardial Infarction; Postoperative Complications; Random Allocation; Sulfinpyrazone; Thiophenes; Ticlopidine | 1986 |
Controlled trial of desmopressin in liver cirrhosis and other conditions associated with a prolonged bleeding time.
Topics: Adolescent; Adult; Aged; Aspirin; Bleeding Time; Clinical Trials as Topic; Deamino Arginine Vasopressin; Female; Humans; Liver Cirrhosis; Male; Middle Aged; Platelet Count; Platelet Function Tests; Random Allocation; Thiophenes; Thrombocytopenia; Ticlopidine; von Willebrand Factor | 1986 |
Evaluation of antiplatelet agents in the prevention of aorto-coronary bypass occlusion.
Topics: Administration, Oral; Anticoagulants; Aspirin; Blood Platelets; Clinical Trials as Topic; Coronary Artery Bypass; Coronary Disease; Dipyridamole; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fibrinolytic Agents; Graft Occlusion, Vascular; Heparin; Humans; Platelet Aggregation; Saphenous Vein; Sulfinpyrazone; Thiophenes; Ticlopidine | 1986 |
[Pathophysiology and treatment of thrombosis. (2) The effect of ticlopidine on TIA compared with aspirin. A double-blind, 12-month and open 24-month follow-up study].
Topics: Aspirin; Clinical Trials as Topic; Double-Blind Method; Follow-Up Studies; Humans; Ischemic Attack, Transient; Ticlopidine | 1987 |
[Aftercare of heart infarct patients to reduce the risk of a subsequent infarction].
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Anticoagulants; Aspirin; Clinical Trials as Topic; Dipyridamole; Humans; Hypolipidemic Agents; Myocardial Infarction; Patient Care Planning; Platelet Aggregation; Recurrence; Risk; Sulfinpyrazone; Thiophenes; Ticlopidine | 1983 |
The North American ticlopidine aspirin stroke study: structure, stratification variables, and patient characteristics.
Topics: Age Factors; Aged; Anticoagulants; Aspirin; Cerebrovascular Disorders; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Random Allocation; Thiophenes; Ticlopidine | 1984 |
The effect of ticlopidine on TIA compared with aspirin: a double-blind, twelve-month follow-up study.
Topics: Anticoagulants; Aspirin; Clinical Trials as Topic; Double-Blind Method; Follow-Up Studies; Humans; Ischemic Attack, Transient; Thiophenes; Ticlopidine | 1984 |
Registry of prospective clinical trials--fifth report.
Topics: Aspirin; Clinical Trials as Topic; Coronary Artery Bypass; Coronary Disease; Dipyridamole; Double-Blind Method; Heart Valve Prosthesis; Heparin; Humans; Intermittent Claudication; Myocardial Infarction; Prospective Studies; Registries; Thiophenes; Thromboembolism; Thrombophlebitis; Thrombosis; Ticlopidine | 1982 |
[Significance of combined use of anticoagulants and antiplatelet agents in the early stage after prosthetic valve replacement].
Topics: Adult; Aged; Anticoagulants; Aspirin; Blood Coagulation; Depression, Chemical; Drug Therapy, Combination; Female; Heart Valve Diseases; Heart Valve Prosthesis; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine; Warfarin | 1995 |
Intracoronary stenting without coumadin: one month results of a French multicenter study.
Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Coronary Disease; Drug Therapy, Combination; Electrocardiography; Female; Follow-Up Studies; Heparin, Low-Molecular-Weight; Humans; Male; Middle Aged; Prospective Studies; Stents; Thrombosis; Ticlopidine | 1995 |
Two-pronged antiplatelet therapy with aspirin and ticlopidine without systemic anticoagulation: an alternative therapeutic strategy after bailout stent implantation.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Coronary Disease; Drug Therapy, Combination; Female; Heparin; Humans; Injections, Intravenous; Male; Middle Aged; Postoperative Complications; Prognosis; Prospective Studies; Stents; Ticlopidine | 1995 |
Hydroxyurea for patients with essential thrombocythemia and a high risk of thrombosis.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Female; Follow-Up Studies; Hemorrhage; Humans; Hydroxyurea; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Risk; Thrombocytosis; Thromboembolism; Ticlopidine | 1995 |
Intracoronary stenting without anticoagulation accomplished with intravascular ultrasound guidance.
Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Aspirin; Catheterization; Coronary Angiography; Coronary Disease; Coronary Thrombosis; Coronary Vessels; Female; Follow-Up Studies; Humans; Male; Middle Aged; Stents; Ticlopidine; Ultrasonography | 1995 |
[Ticlopidine and aspirin in the treatment of unstable angina: comparative evaluation of their effect of anti-aggregation and platelet membranes].
Topics: Adult; Aged; Angina, Unstable; Anti-Arrhythmia Agents; Aspirin; Cholesterol; Heparin; Humans; Male; Middle Aged; Phospholipids; Platelet Aggregation; Platelet Membrane Glycoproteins; Retrospective Studies; Ticlopidine | 1993 |
Compliance with antiplatelet therapy in patients with ischemic cerebrovascular disease. Assessment by platelet aggregation testing.
Topics: Adenosine Diphosphate; Aged; Aspirin; Cerebral Infarction; Collagen; Drug Monitoring; Female; Follow-Up Studies; Humans; Inpatients; Intracranial Embolism and Thrombosis; Ischemic Attack, Transient; Male; Outpatients; Patient Compliance; Platelet Aggregation; Ticlopidine | 1994 |
[Antiplatelet therapy in patients with cerebral thrombosis at the chronic phase--assessment of its effect on coagulation and fibrinolytic parameters].
Topics: Aged; Aspirin; Blood Coagulation; Cerebrovascular Disorders; Chronic Disease; Fibrinolysis; Humans; Intracranial Embolism and Thrombosis; Platelet Aggregation Inhibitors; Ticlopidine | 1994 |
Comparison of symptomatic and asymptomatic reinfarctions after small subcortical stroke.
Topics: Aged; Aspirin; Cerebral Angiography; Cerebral Infarction; Cholesterol, HDL; Female; Fibrinogen; Follow-Up Studies; Hematocrit; Humans; Intracranial Arteriosclerosis; Lipoprotein(a); Male; Middle Aged; Neurologic Examination; Recurrence; Risk Factors; Ticlopidine; Tomography, X-Ray Computed | 1994 |
Shear-induced platelet aggregation in cerebral ischemia.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; beta-Thromboglobulin; Brain Ischemia; Cerebral Infarction; Female; Fibrinogen; Hematologic Tests; Humans; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation; Platelet Count; Ticlopidine; Time Factors; von Willebrand Factor | 1994 |
[A comparison of the gastroduodenal tolerance of ticlopidine and acetylsalicylic acid].
Topics: Adult; Aspirin; Double-Blind Method; Gastric Mucosa; Humans; Male; Purpura; Stomach Diseases; Stomach Ulcer; Ticlopidine | 1993 |
Efficacy of ticlopidine and aspirin for prevention of reversible cerebrovascular ischemic events. The Ticlopidine Aspirin Stroke Study.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cerebrovascular Disorders; Double-Blind Method; Female; Follow-Up Studies; Humans; Ischemic Attack, Transient; Male; Middle Aged; Ticlopidine; Time Factors | 1993 |
The efficacy and safety of ticlopidine and aspirin in non-whites: analysis of a patient subgroup from the Ticlopidine Aspirin Stroke Study.
Topics: Aged; Aspirin; Brain Ischemia; Cerebrovascular Disorders; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neutropenia; Racial Groups; Ticlopidine; White People | 1993 |
A randomized comparison of combined ticlopidine and aspirin therapy versus aspirin therapy alone after successful intravascular ultrasound-guided stent implantation.
Topics: Aged; Angiography; Aspirin; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine; Ultrasonics | 1996 |
Haemodynamic changes induced by the correction of anaemia by erythropoietin: role of antiplatelet therapy.
Topics: Adult; Aged; Anemia; Aspirin; Dipyridamole; Erythropoietin; Female; Hemodynamics; Humans; Male; Middle Aged; Oxazoles; Platelet Aggregation Inhibitors; Prospective Studies; Recombinant Proteins; Renal Dialysis; Ticlopidine; Time Factors; Uremia | 1995 |
Heparin-coated Palmaz-Schatz stents in human coronary arteries. Early outcome of the Benestent-II Pilot Study.
Topics: Aspirin; Coronary Angiography; Coronary Disease; Coronary Vessels; Disease-Free Survival; Equipment Design; Exercise Test; Female; Follow-Up Studies; Heparin; Humans; Length of Stay; Male; Middle Aged; Pilot Projects; Safety; Stents; Ticlopidine; Treatment Outcome; Warfarin | 1996 |
A randomized comparison of antiplatelet and anticoagulant therapy after the placement of coronary-artery stents.
Topics: Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Coronary Disease; Drug Therapy, Combination; Female; Heparin; Humans; Male; Middle Aged; Phenprocoumon; Platelet Aggregation Inhibitors; Postoperative Complications; Prospective Studies; Stents; Ticlopidine | 1996 |
Development of large platelet aggregates from small aggregates as determined by laser-light scattering: effects of aggregant concentration and antiplatelet medication.
Topics: Aged; Aspirin; Flow Cytometry; Humans; In Vitro Techniques; Lasers; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine | 1996 |
[Coronary artery stenting without antivitamin K. Results after a month].
Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Coronary Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Heparin, Low-Molecular-Weight; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Stents; Thrombolytic Therapy; Thrombosis; Ticlopidine; Treatment Outcome | 1996 |
Intracoronary stent implantation without ultrasound guidance and with replacement of conventional anticoagulation by antiplatelet therapy. 30-day clinical outcome of the French Multicenter Registry.
Topics: Aged; Anticoagulants; Aspirin; Coronary Vessels; Female; France; Hemorrhage; Heparin, Low-Molecular-Weight; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Registries; Stents; Ticlopidine; Time Factors; Treatment Outcome; Ultrasonics | 1996 |
Combined antiplatelet therapy with ticlopidine and aspirin. A simplified approach to intracoronary stent management.
Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Aspirin; Chi-Square Distribution; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Female; Humans; Incidence; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Stents; Ticlopidine; Treatment Outcome | 1996 |
Hemostaseologic and hematologic parameters with aspirin and ticlopidine treatment in patients with cerebrovascular disease: a cross-over study.
Topics: Adenosine Diphosphate; Aged; Aspirin; Cerebrovascular Disorders; Collagen; Cross-Over Studies; Epinephrine; Female; Fibrinogen; Hemostasis; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Prospective Studies; Ticlopidine | 1996 |
Asymptomatic circulating cerebral emboli and cerebral blood flow velocity under aspirin and ticlopidine in patients with cerebrovascular disease.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Flow Velocity; Carotid Stenosis; Cell Survival; Cerebrovascular Circulation; Cerebrovascular Disorders; Female; Humans; Intracranial Embolism and Thrombosis; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Reproducibility of Results; Ticlopidine; Ultrasonography, Doppler, Transcranial | 1996 |
A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). CAPRIE Steering Committee.
Topics: Adult; Arteriosclerosis; Aspirin; Brain Ischemia; Clopidogrel; Cohort Studies; Double-Blind Method; Female; Follow-Up Studies; Hemorrhage; Humans; Male; Myocardial Ischemia; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 1996 |
[Elective coronary implantation of a newly developed stent without conventional anticoagulation].
Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Coronary Disease; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Prosthesis Design; Stents; Thrombosis; Ticlopidine | 1996 |
Ticlopidine and aspirin pretreatment reduces coagulation and platelet activation during coronary dilation procedures.
Topics: Angioplasty, Balloon, Coronary; Antifibrinolytic Agents; Aspirin; Atherectomy, Coronary; Coronary Disease; Drug Therapy, Combination; Female; Hemostasis; Heparin; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Premedication; Serotonin; Stents; Ticlopidine | 1997 |
High pressure assisted coronary stent implantation accomplished without intravascular ultrasound guidance and subsequent anticoagulation.
Topics: Anticoagulants; Aspirin; Case-Control Studies; Coronary Angiography; Coronary Disease; Coronary Thrombosis; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Time Factors; Treatment Outcome; Ultrasonography, Interventional | 1997 |
Coronary stent placement in patients with acute myocardial infarction: comparison of clinical and angiographic outcome after randomization to antiplatelet or anticoagulant therapy.
Topics: Anticoagulants; Aspirin; Coronary Angiography; Coronary Disease; Female; Follow-Up Studies; Heparin; Humans; Male; Middle Aged; Myocardial Infarction; Phenprocoumon; Platelet Aggregation Inhibitors; Recurrence; Stents; Survival Rate; Ticlopidine; Time Factors; Treatment Outcome | 1997 |
Pretreatment with aspirin and ticlopidine confers lower thrombogenic potential of radiofrequency catheter ablation.
Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Aspirin; Catheter Ablation; Child; Electrophysiology; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Thromboembolism; Ticlopidine | 1997 |
Results of a consecutive series of patients receiving only antiplatelet therapy after optimized stent implantation. Comparison of aspirin alone versus combined ticlopidine and aspirin therapy.
Topics: Angioplasty, Balloon; Aspirin; Coronary Angiography; Coronary Disease; Drug Therapy, Combination; Equipment Design; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Stents; Thrombosis; Ticlopidine; Time Factors; Ultrasonography, Interventional | 1997 |
Effects of aspirin on platelet aggregation in smokers and nonsmokers.
Topics: Adenosine Triphosphate; Adult; Aspirin; Cross-Over Studies; Electric Impedance; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Smoking; Ticlopidine | 1997 |
Aspirin plus either dipyridamole or ticlopidine is effective in preventing recurrent myocardial infarction. Secondary Prevention Group.
Topics: Aged; Aspirin; Dipyridamole; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Recurrence; Ticlopidine | 1997 |
[Primary and secondary prevention of ischemic cerebrovascular accidents of arteriosclerosis by platelet inhibitors].
Topics: Arteriosclerosis; Aspirin; Brain Ischemia; Cerebrovascular Disorders; Dipyridamole; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Male; Platelet Aggregation Inhibitors; Primary Prevention; Ticlopidine | 1996 |
Coronary stenting (Cordis) without anticoagulation.
Topics: Anticoagulants; Aspirin; Coronary Angiography; Coronary Disease; Coronary Thrombosis; Evaluation Studies as Topic; Fibrinolytic Agents; Humans; Middle Aged; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Time Factors; Warfarin | 1997 |
Major benefit from antiplatelet therapy for patients at high risk for adverse cardiac events after coronary Palmaz-Schatz stent placement: analysis of a prospective risk stratification protocol in the Intracoronary Stenting and Antithrombotic Regimen (ISA
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Cardiovascular Diseases; Combined Modality Therapy; Coronary Disease; Death, Sudden, Cardiac; Fibrinolytic Agents; Heparin; Humans; Incidence; Myocardial Infarction; Phenprocoumon; Platelet Aggregation Inhibitors; Postoperative Complications; Prospective Studies; Recurrence; Reoperation; Risk Factors; Stents; Ticlopidine | 1997 |
[Recent antithrombotic gold standard?].
Topics: Arteriosclerosis; Aspirin; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine; Treatment Outcome | 1997 |
Antiplatelet effect of ticlopidine after coronary stenting.
Topics: Aged; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Constriction, Pathologic; Coronary Disease; Drug Therapy, Combination; Female; Flow Cytometry; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Count; Platelet Glycoprotein GPIIb-IIIa Complex; Stents; Ticlopidine; Treatment Outcome | 1997 |
Coronary stenting after rotational atherectomy in calcified and complex lesions. Angiographic and clinical follow-up results.
Topics: Aged; Aspirin; Atherectomy, Coronary; Calcinosis; Coronary Angiography; Coronary Disease; Coronary Thrombosis; Female; Fibrinolytic Agents; Follow-Up Studies; Heparin; Humans; Male; Middle Aged; Recurrence; Retrospective Studies; Stents; Ticlopidine; Ultrasonography; Warfarin | 1997 |
Sustained platelet glycoprotein IIb/IIIa blockade with oral xemilofiban in 170 patients after coronary stent deployment.
Topics: Abciximab; Administration, Oral; Aged; Antibodies, Monoclonal; Aspirin; Benzamidines; Coronary Disease; Dose-Response Relationship, Drug; Female; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Single-Blind Method; Stents; Thrombosis; Ticlopidine | 1997 |
Early versus late coronary stenting following acute myocardial infarction: results of the STENTIM I Study (French Registry of Stenting in Acute Myocardial Infarction).
Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Feasibility Studies; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Prospective Studies; Registries; Stents; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 1997 |
[Immediate and long-term clinical and angiographic results of the Wiktor stent in the treatment of chronic coronary occlusions].
Topics: Analysis of Variance; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Chronic Disease; Coronary Angiography; Coronary Disease; Female; Follow-Up Studies; Humans; Logistic Models; Male; Middle Aged; Platelet Aggregation Inhibitors; Recurrence; Stents; Ticlopidine; Time Factors; Warfarin | 1997 |
Wiktor stent for treatment of chronic total coronary artery occlusions: short- and long-term clinical and angiographic results from a large multicenter experience.
Topics: Analysis of Variance; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Catheterization, Peripheral; Confidence Intervals; Coronary Angiography; Coronary Disease; Equipment Design; Female; Follow-Up Studies; Hemorrhage; Humans; Logistic Models; Longitudinal Studies; Male; Middle Aged; Myocardial Infarction; Myocardial Revascularization; Odds Ratio; Platelet Aggregation Inhibitors; Recurrence; Stents; Survival Rate; Thrombosis; Ticlopidine; Treatment Outcome; Warfarin | 1998 |
PAMI (Primary Angioplasty in Myocardial Infarction) Stent Pilot Trial.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Drug Therapy, Combination; Follow-Up Studies; Humans; Myocardial Infarction; Pilot Projects; Platelet Aggregation Inhibitors; Postoperative Complications; Recurrence; Safety; Stents; Ticlopidine; Treatment Outcome | 1998 |
Enhancement of platelet inhibition of ticlopidine plus aspirin vs aspirin alone given prior to elective PTCA.
Topics: Adult; Aged; Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Preoperative Care; Prospective Studies; Random Allocation; Stents; Ticlopidine | 1998 |
Comparison of antiplatelet effects of aspirin, ticlopidine, or their combination after stent implantation.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Coronary Disease; Drug Therapy, Combination; Fibrinogen; Humans; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Stents; Ticlopidine; Time Factors | 1998 |
One-month results of coronary stenting in patients > or = 75 years of age.
Topics: Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Drug Therapy, Combination; Female; Heparin, Low-Molecular-Weight; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Retrospective Studies; Stents; Ticlopidine; Treatment Outcome | 1998 |
Randomised placebo-controlled and balloon-angioplasty-controlled trial to assess safety of coronary stenting with use of platelet glycoprotein-IIb/IIIa blockade.
Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Coronary Disease; Coronary Thrombosis; Drug Therapy, Combination; Female; Hemorrhage; Humans; Immunoglobulin Fab Fragments; Incidence; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Postoperative Complications; Reoperation; Ticlopidine | 1998 |
Enhanced onset of platelet inhibition with a loading dose of ticlopidine in ASA-treated stable coronary patients.
Topics: Angina Pectoris; Aspirin; Blood Platelets; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine | 1998 |
A double-blind randomized comparison of combined aspirin and ticlopidine therapy versus aspirin or ticlopidine alone on experimental arterial thrombogenesis in humans.
Topics: Adult; Arteries; Aspirin; Blood; Blood Platelets; Collagen; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Glass; Humans; Male; Models, Biological; Platelet Aggregation Inhibitors; Thromboplastin; Thrombosis; Ticlopidine | 1998 |
Acute hemodynamic interaction of aspirin and ticlopidine with enalapril: results of a double-blind, randomized comparative trial.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Double-Blind Method; Enalapril; Female; Hemodynamics; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine | 1998 |
Randomised comparison of implantation of heparin-coated stents with balloon angioplasty in selected patients with coronary artery disease (Benestent II)
Topics: Adult; Aged; Angina Pectoris; Angina, Unstable; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Coronary Angiography; Equipment Design; Female; Heparin; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Stents; Survival Analysis; Ticlopidine; Treatment Outcome | 1998 |
Low-molecular-weight heparins in coronary stenting (the ENTICES trial). ENoxaparin and TIClopidine after Elective Stenting.
Topics: Aged; Aspirin; Coronary Angiography; Coronary Thrombosis; Drug Therapy, Combination; Enoxaparin; Female; Fibrinolytic Agents; Follow-Up Studies; Heparin, Low-Molecular-Weight; Humans; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Treatment Outcome | 1998 |
[Antithrombotic agents in unstable angina. Review of clinical trials].
Topics: Angina, Unstable; Aspirin; Clopidogrel; Fibrinolytic Agents; Heparin, Low-Molecular-Weight; Hirudin Therapy; Humans; Platelet Aggregation Inhibitors; Thrombolytic Therapy; Ticlopidine | 1998 |
Randomized multicenter comparison of conventional anticoagulation versus antiplatelet therapy in unplanned and elective coronary stenting. The full anticoagulation versus aspirin and ticlopidine (fantastic) study.
Topics: Administration, Oral; Aged; Anticoagulants; Arterial Occlusive Diseases; Aspirin; Coronary Disease; Drug Therapy, Combination; Elective Surgical Procedures; Female; Follow-Up Studies; Hemorrhage; Heparin; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Treatment Outcome | 1998 |
The results of CAPRIE, IST and CAST. Clopidogrel vs. Aspirin in Patients at Risk of Ischaemic Events. International Stroke Trial. Chinese Acute Stroke Trial.
Topics: Aspirin; Cerebrovascular Disorders; Clopidogrel; Double-Blind Method; Humans; Ischemia; Myocardial Infarction; Platelet Aggregation Inhibitors; Recurrence; Ticlopidine | 1998 |
Randomized evaluation of anticoagulation versus antiplatelet therapy after coronary stent implantation in high-risk patients: the multicenter aspirin and ticlopidine trial after intracoronary stenting (MATTIS).
Topics: Adult; Aged; Anticoagulants; Aspirin; Coronary Thrombosis; Female; Humans; Male; Middle Aged; Patient Compliance; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 1998 |
[Effectiveness of unstable angina pectoris treatment by aggregation inhibitors ticlid and aspirin].
Topics: Adult; Aged; Aged, 80 and over; Angina, Unstable; Aspirin; Electrocardiography, Ambulatory; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 1998 |
PTCA of degenerated vein grafts: experience of two periods (1992-93 and 1996-97) in 780 patients.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Blood Vessel Prosthesis; Coronary Artery Bypass; Coronary Disease; Female; Follow-Up Studies; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Polytetrafluoroethylene; Reoperation; Saphenous Vein; Stents; Ticlopidine; Treatment Outcome | 1998 |
A clinical trial comparing three antithrombotic-drug regimens after coronary-artery stenting. Stent Anticoagulation Restenosis Study Investigators.
Topics: Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Coronary Disease; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Single-Blind Method; Stents; Thrombosis; Ticlopidine; Warfarin | 1998 |
Pretreatment with antithrombotic agents during radiofrequency catheter ablation: a randomized comparison of aspirin versus ticlopidine.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Biomarkers; Catheter Ablation; Child; Double-Blind Method; Electrophysiology; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Preoperative Care; Ticlopidine | 1998 |
Results of the CAPRIE trial: efficacy and safety of clopidogrel. Clopidogrel versus aspirin in patients at risk of ischaemic events.
Topics: Arteriosclerosis; Aspirin; Cerebrovascular Disorders; Clopidogrel; Follow-Up Studies; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk Assessment; Ticlopidine; Treatment Outcome | 1998 |
Advances in post stenting medication protocol.
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Coronary Disease; Drug Therapy, Combination; Female; Heparin; Heparin, Low-Molecular-Weight; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Recurrence; Stents; Ticlopidine | 1995 |
The effect of aspirin, ticlopidine and their low-dose combination on platelet aggregability in acute ischemic stroke: a short duration follow-up study.
Topics: Acute Disease; Aged; Aspirin; Brain Ischemia; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Time Factors | 1999 |
Effectiveness of clopidogrel and aspirin versus ticlopidine and aspirin in preventing stent thrombosis after coronary stent implantation.
Topics: Aged; Aspirin; Clopidogrel; Coronary Angiography; Coronary Disease; Coronary Thrombosis; Diarrhea; Drug Eruptions; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Neutropenia; Platelet Aggregation Inhibitors; Postoperative Complications; Safety; Stents; Ticlopidine; Treatment Outcome | 1999 |
Single-dose pharmacodynamics of clopidogrel.
Topics: Administration, Oral; Adult; Aspirin; Clopidogrel; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine | 1999 |
Comparison of cilostazol versus ticlopidine therapy after stent implantation.
Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Coronary Disease; Coronary Thrombosis; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Recurrence; Stents; Tetrazoles; Ticlopidine; Treatment Outcome | 1999 |
Comparative safety and tolerability of clopidogrel and aspirin: results from CAPRIE. CAPRIE Steering Committee and Investigators. Clopidogrel versus aspirin in patients at risk of ischaemic events.
Topics: Arteriosclerosis; Aspirin; Cerebrovascular Disorders; Clopidogrel; Double-Blind Method; Gastrointestinal Diseases; Hemorrhage; Humans; Myocardial Infarction; Neutropenia; Platelet Aggregation Inhibitors; Stroke; Thrombocytopenia; Ticlopidine; Time Factors; Treatment Outcome | 1999 |
beta-Particle-emitting radioactive stent implantation. A safety and feasibility study.
Topics: Adult; Aged; Aspirin; Beta Particles; Brachytherapy; Coronary Angiography; Coronary Disease; Feasibility Studies; Female; Follow-Up Studies; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Patient Selection; Phosphorus Radioisotopes; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 1999 |
Impact of cilostazol on clinical and angiographic outcome after primary stenting for acute myocardial infarction.
Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Coronary Angiography; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Myocardial Infarction; Premedication; Stents; Tetrazoles; Ticlopidine; Treatment Outcome | 1999 |
Clopidogrel as adjunctive antiplatelet therapy during coronary stenting.
Topics: Administration, Oral; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Thrombosis; Drug Therapy, Combination; Female; Hospital Mortality; Humans; Length of Stay; Male; Middle Aged; Odds Ratio; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prospective Studies; Safety; Stents; Ticlopidine; Treatment Outcome | 1999 |
Clopidogrel versus ticlopidine after intracoronary stent placement.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Thrombosis; Drug Therapy, Combination; Female; Hospital Mortality; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Safety; Secondary Prevention; Stents; Ticlopidine; Time Factors; Treatment Outcome | 1999 |
Changes in levels of factor VII and protein S after acute myocardial infarction: effects of low-dose warfarin.
Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Antigens; Aspirin; Brain Ischemia; Death, Sudden, Cardiac; Drug Therapy, Combination; Factor VII; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Peptide Fragments; Prognosis; Proportional Hazards Models; Prospective Studies; Protein C; Protein S; Prothrombin; Recurrence; Risk; Single-Blind Method; Thrombolytic Therapy; Thrombophilia; Ticlopidine; Treatment Outcome; Warfarin | 1999 |
Usefulness of cilostazol versus ticlopidine in coronary artery stenting.
Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Aspirin; Cause of Death; Cilostazol; Coronary Angiography; Coronary Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Recurrence; Stents; Survival Rate; Tetrazoles; Ticlopidine; Treatment Outcome | 1999 |
Chest pain--a strong predictor of adverse cardiac events following precutaneous intervention (from the Evaluation of Platelet IIb/IIIa Inhibitor for Stenting Trial [EPISENT])].
Topics: Abciximab; Aged; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Chest Pain; Coronary Disease; Drug Therapy, Combination; Electrocardiography; Female; Humans; Immunoglobulin Fab Fragments; Male; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prognosis; Prospective Studies; Recurrence; Stents; Ticlopidine | 1999 |
A randomized comparison of clopidogrel and aspirin versus ticlopidine and aspirin after the placement of coronary-artery stents.
Topics: Aged; Aspirin; Clopidogrel; Coronary Thrombosis; Coronary Vessels; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Stents; Ticlopidine; Treatment Outcome | 2000 |
[Aspirin vs ticlid and their combination in patients with acute myocardial infarction].
Topics: Aged; Aspirin; Blood Platelets; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2000 |
Pharmacokinetics and pharmacodynamics of sibrafiban alone or in combination with ticlopidine and aspirin.
Topics: Adult; Aspirin; Drug Interactions; Humans; Male; Oximes; Piperidines; Platelet Aggregation Inhibitors; Prodrugs; Ticlopidine | 2000 |
The effect of antiplatelet drugs, heparin, and preanalytical variables on platelet function detected by the platelet function analyzer (PFA-100).
Topics: Abciximab; Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Blood Platelets; Blood Specimen Collection; Calcium; Chelating Agents; Computers; Coronary Disease; Dose-Response Relationship, Drug; Equipment Design; Heparin; Humans; Immunoglobulin Fab Fragments; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine | 1999 |
Antiplatelet is superior to anticoagulant treatment after coronary stenting: fewer coronary and other events within 30 days after stenting.
Topics: Acenocoumarol; Aged; Angina Pectoris; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Coronary Disease; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Prospective Studies; Stents; Ticlopidine | 2000 |
Increased platelet aggregability in response to shear stress in acute myocardial infarction and its inhibition by combined therapy with aspirin and cilostazol after coronary intervention.
Topics: Aged; Aspirin; Cilostazol; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation Inhibitors; Tetrazoles; Ticlopidine; von Willebrand Factor | 2000 |
[ASS or clopidogrel? In high vascular risk it is best to give both].
Topics: Arteriosclerosis; Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine | 2000 |
[The drug prevention of postoperative thromboses in patients with critical lower limb ischemia].
Topics: Anticoagulants; Aspirin; Critical Illness; Humans; Ischemia; Leg; Nadroparin; Platelet Aggregation Inhibitors; Postoperative Care; Postoperative Complications; Thrombosis; Ticlopidine; Time Factors; Vascular Surgical Procedures | 1999 |
Early potent antithrombotic effect with combined aspirin and a loading dose of clopidogrel on experimental arterial thrombogenesis in humans.
Topics: Adult; Arteries; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine; Time Factors | 2000 |
Gastroduodenal tolerance of 75 mg clopidogrel versus 325 mg aspirin in healthy volunteers. A gastroscopic study.
Topics: Adult; Aspirin; Clopidogrel; Double-Blind Method; Drug Hypersensitivity; Gastric Mucosa; Gastritis; Gastroscopy; Humans; Intestinal Mucosa; Male; Patient Compliance; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine | 2000 |
Reduction in the need for hospitalization for recurrent ischemic events and bleeding with clopidogrel instead of aspirin. CAPRIE investigators.
Topics: Aspirin; Brain Ischemia; Cause of Death; Clopidogrel; Confidence Intervals; Double-Blind Method; Female; Hemorrhage; Hospitalization; Humans; Incidence; Ischemia; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Probability; Prognosis; Proportional Hazards Models; Risk Assessment; Secondary Prevention; Survival Analysis; Ticlopidine | 2000 |
Final results of the Can Routine Ultrasound Influence Stent Expansion (CRUISE) study.
Topics: Aspirin; Coronary Angiography; Coronary Disease; Coronary Vessels; Coumarins; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Myocardial Infarction; Stents; Ticlopidine; Treatment Outcome; Ultrasonography, Interventional | 2000 |
Plasma levels of C-reactive protein after coronary stent implantation.
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Biomarkers; C-Reactive Protein; Coronary Angiography; Coronary Disease; Dipyridamole; Drug Therapy, Combination; Female; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Phenprocoumon; Platelet Aggregation Inhibitors; Prognosis; Stents; Ticlopidine | 2000 |
A randomized comparison of elective high-pressure stenting with balloon angioplasty: six-month angiographic and two-year clinical follow-up. On behalf of AS (Angioplasty or Stent) trial investigators.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Combined Modality Therapy; Coronary Angiography; Coronary Disease; Follow-Up Studies; Humans; Poland; Recurrence; Single-Blind Method; Stents; Survival Rate; Ticlopidine; Treatment Outcome | 2000 |
Double-blind study of the safety of clopidogrel with and without a loading dose in combination with aspirin compared with ticlopidine in combination with aspirin after coronary stenting : the clopidogrel aspirin stent international cooperative study (CLAS
Topics: Aged; Aspirin; Clopidogrel; Coronary Vessels; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Humans; International Cooperation; Male; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Treatment Outcome | 2000 |
[Subacute thrombosis with antiplatelet treatment in a non-selected population of intracoronary stents: incidence and predictors].
Topics: Acute Disease; Aspirin; Coronary Thrombosis; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2000 |
Inhibition of restenosis with beta-emitting radiotherapy: Report of the Proliferation Reduction with Vascular Energy Trial (PREVENT).
Topics: Angioplasty, Balloon, Coronary; Aspirin; Automation; Beta Particles; Combined Modality Therapy; Coronary Angiography; Coronary Disease; Coronary Vessels; Dose-Response Relationship, Radiation; Drug Delivery Systems; Humans; Phosphorus Radioisotopes; Platelet Aggregation Inhibitors; Radiopharmaceuticals; Stents; Ticlopidine; Time Factors; Treatment Outcome | 2000 |
[Clinical effectiveness and specific action of antiaggregants in patients with unstable angina].
Topics: Angina, Unstable; Aspirin; Electrocardiography, Ambulatory; Female; Hemostasis; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2000 |
Antiplatelet effects of clopidogrel compared with aspirin after myocardial infarction: enhanced inhibitory effects of combination therapy.
Topics: Adenosine Diphosphate; Adult; Aged; Antigens, CD; Aspirin; Blood; Clopidogrel; Collagen; Dose-Response Relationship, Drug; Drug Therapy, Combination; Dual Specificity Phosphatase 2; Humans; Middle Aged; Myocardial Infarction; P-Selectin; Peptide Fragments; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Prospective Studies; Protein Phosphatase 2; Protein Tyrosine Phosphatases; Tetraspanin 30; Ticlopidine | 2000 |
Effects of cilostazol on angiographic restenosis after coronary stent placement.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Coronary Angiography; Coronary Disease; Disease-Free Survival; Drug Therapy, Combination; Follow-Up Studies; Humans; Phosphodiesterase Inhibitors; Platelet Aggregation Inhibitors; Recurrence; Stents; Tetrazoles; Ticlopidine | 2000 |
Acute antithrombotic effect of a front-loaded regimen of clopidogrel in patients with atherosclerosis on aspirin.
Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Double-Blind Method; Drug Therapy, Combination; Fibrinogen; Fibrinolytic Agents; Humans; Perfusion; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors | 2000 |
Effect of aspirin and ticlopidine on plasma tissue factor levels in stable and unstable angina pectoris.
Topics: Angina Pectoris; Angina, Unstable; Angioplasty, Balloon, Coronary; Antithrombin III; Aspirin; Atherectomy, Coronary; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Peptide Hydrolases; Platelet Aggregation Inhibitors; Premedication; Stents; Thromboplastin; Ticlopidine; Time Factors | 2000 |
A randomized trial comparing stenting with balloon angioplasty in small vessels in patients with symptomatic coronary artery disease. ISAR-SMART Study Investigators. Intracoronary Stenting or Angioplasty for Restenosis Reduction in Small Arteries.
Topics: Abciximab; Aged; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Chemotherapy, Adjuvant; Coronary Angiography; Coronary Disease; Disease-Free Survival; Female; Graft Occlusion, Vascular; Humans; Immunoglobulin Fab Fragments; Male; Stents; Ticlopidine; Treatment Outcome; Vascular Patency | 2000 |
The Clopidogrel in Unstable angina to prevent Recurrent Events (CURE) trial programme; rationale, design and baseline characteristics including a meta-analysis of the effects of thienopyridines in vascular disease.
Topics: Angina, Unstable; Aspirin; Clopidogrel; Humans; Meta-Analysis as Topic; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine; Vascular Diseases | 2000 |
Effect of a high loading dose of clopidogrel on platelet function in patients undergoing coronary stent placement.
Topics: Aspirin; Clopidogrel; Coronary Disease; Coronary Thrombosis; Drug Administration Schedule; Drug Therapy, Combination; Humans; Platelet Activation; Platelet Aggregation; Stents; Ticlopidine | 2001 |
Local delivery of enoxaparin to decrease restenosis after stenting: results of initial multicenter trial: Polish-American Local Lovenox NIR Assessment study (The POLONIA study).
Topics: Anticoagulants; Aspirin; Drug Administration Routes; Drug Delivery Systems; Enoxaparin; Female; Follow-Up Studies; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation Inhibitors; Poland; Prospective Studies; Stents; Ticlopidine; Treatment Outcome | 2001 |
Superiority of clopidogrel versus aspirin in patients with prior cardiac surgery.
Topics: Aspirin; Cardiac Surgical Procedures; Clopidogrel; Double-Blind Method; Female; Hospitalization; Humans; Ischemia; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Postoperative Complications; Risk Factors; Ticlopidine | 2001 |
Sustained benefit over four years from an initial combined antiplatelet regimen after coronary stent placement in the ISAR trial. Intracoronary Stenting and Antithrombotic Regimen.
Topics: Angioplasty, Balloon; Anticoagulants; Aspirin; Coronary Angiography; Coronary Disease; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Phenprocoumon; Platelet Aggregation Inhibitors; Recurrence; Statistics, Nonparametric; Stents; Survival Analysis; Ticlopidine; Treatment Outcome | 2001 |
Rationale, design and organization of the Second Chinese Cardiac Study (CCS-2): a randomized trial of clopidogrel plus aspirin, and of metoprolol, among patients with suspected acute myocardial infarction. Second Chinese Cardiac Study (CCS-2) Collaborativ
Topics: Adrenergic beta-Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; China; Clopidogrel; Drug Therapy, Combination; Humans; Metoprolol; Myocardial Infarction; Platelet Aggregation Inhibitors; Research Design; Ticlopidine | 2000 |
A safe and effective regimen without heparin therapy after successful primary coronary stenting in patients with acute myocardial infarction.
Topics: Aged; Aspirin; Combined Modality Therapy; Coronary Angiography; Coronary Thrombosis; Coronary Vessels; Drug Therapy, Combination; Female; Fibrinolytic Agents; Hemorrhage; Heparin; Humans; Male; Middle Aged; Myocardial Infarction; Stents; Ticlopidine | 2000 |
[Application of preparation endotelon in complex treatment of chronic arterial insufficiency of lower extremities].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Arterial Occlusive Diseases; Aspirin; Biflavonoids; Catechin; Drug Therapy, Combination; Female; Humans; Ischemia; Leg; Male; Middle Aged; Platelet Aggregation Inhibitors; Proanthocyanidins; Ticlopidine; Treatment Outcome | 2000 |
Ticlopidine versus aspirin after myocardial infarction (STAMI) trial.
Topics: Adult; Aged; Aspirin; Cause of Death; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Recurrence; Survival Rate; Thrombolytic Therapy; Ticlopidine | 2001 |
Oral anticoagulant therapy during and after coronary angioplasty the intensity and duration of anticoagulation are essential to reduce thrombotic complications.
Topics: Administration, Oral; Aneurysm, False; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Cerebral Hemorrhage; Coronary Artery Disease; Coronary Restenosis; Coumarins; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Hemorrhage; Humans; International Normalized Ratio; Male; Middle Aged; Postoperative Complications; Prospective Studies; Risk; Stents; Thrombosis; Ticlopidine; Treatment Outcome; Vascular Patency | 2001 |
Efficacy and safety of ticlopidine monotherapy versus ticlopidine and aspirin after coronary artery stenting: follow-up results of a randomized study.
Topics: Aged; Aspirin; Coronary Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Stents; Ticlopidine; Treatment Outcome | 2001 |
Inhibition by combined therapy with ticlopidine and aspirin of enhanced platelet aggregation during physical exercise in patients with coronary artery disease.
Topics: Adenine Nucleotides; Adult; Aged; Aspirin; Coronary Disease; Coronary Thrombosis; Drug Administration Schedule; Exercise; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2001 |
Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation.
Topics: Acute Disease; Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Electrocardiography; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine | 2001 |
Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE study.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Disease; Double-Blind Method; Female; Humans; Logistic Models; Male; Middle Aged; Myocardial Infarction; Myocardial Revascularization; Platelet Aggregation Inhibitors; Preoperative Care; Proportional Hazards Models; Prospective Studies; Risk; Survival Analysis; Ticlopidine; Treatment Outcome | 2001 |
Measurement of platelet fibrinogen binding and p-selectin expression by flow cytometry in patients with cerebral infarction.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Cerebral Infarction; Drug Therapy, Combination; Female; Fibrinogen; Flow Cytometry; Humans; Male; Middle Aged; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Protein Binding; Ticlopidine | 2001 |
Does ticlopidine reduce reocclusion and other adverse events after successful balloon angioplasty of occluded coronary arteries? Results from the Total Occlusion Study of Canada (TOSCA).
Topics: Angioplasty, Balloon, Coronary; Aspirin; Coronary Disease; Coronary Restenosis; Drug Therapy, Combination; Humans; Ticlopidine; Treatment Outcome | 2001 |
A randomized, placebo-controlled trial of enoxaparin after high-risk coronary stenting: the ATLAST trial.
Topics: Aged; Analysis of Variance; Anticoagulants; Aspirin; Coronary Disease; Coronary Thrombosis; Double-Blind Method; Drug Administration Routes; Drug Therapy, Combination; Enoxaparin; Female; Humans; Male; Middle Aged; Prospective Studies; Risk Factors; Stents; Ticlopidine; Treatment Outcome | 2001 |
Insights from CURE: using clopidogrel on top of standard therapy.
Topics: Aged; Angina, Unstable; Aspirin; Clopidogrel; Double-Blind Method; Female; Follow-Up Studies; Heparin; Humans; Intracranial Arteriosclerosis; Intracranial Thrombosis; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Recurrence; Survival Analysis; Ticlopidine; Treatment Outcome | 2002 |
Aspirin alone antiplatelet regimen after intracoronary placement of the Carbostent: the ANTARES study.
Topics: Adult; Aged; Arterial Occlusive Diseases; Aspirin; Blood Vessel Prosthesis Implantation; Carbon; Coated Materials, Biocompatible; Coronary Angiography; Coronary Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Italy; Male; Middle Aged; Pilot Projects; Platelet Aggregation Inhibitors; Postoperative Complications; Stainless Steel; Stents; Ticlopidine; Time Factors; Treatment Outcome | 2002 |
[Comparative efficacy of tiklid and aspirin in patients with unstable angina].
Topics: Angina, Unstable; Aspirin; Blood Coagulation; Endothelium, Vascular; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prothrombin Time; Ticlopidine | 2001 |
Cessation of embolic signals after antithrombotic prevention is related to reduced risk of recurrent arterioembolic transient ischaemic attack and stroke.
Topics: Aged; Aspirin; Clopidogrel; Female; Fibrinolytic Agents; Follow-Up Studies; Humans; Intracranial Embolism; Ischemic Attack, Transient; Male; Middle Aged; Recurrence; Risk; Ticlopidine; Ultrasonography, Doppler, Color; Ultrasonography, Doppler, Transcranial | 2002 |
Clopidogrel: a CURE in acute coronary syndromes?
Topics: Acute Disease; Aged; Aspirin; Clopidogrel; Coronary Disease; Double-Blind Method; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Treatment Outcome | 2002 |
Effects of combined therapy with clopidogrel and acetylsalicylic acid on platelet glycoprotein expression and aggregation.
Topics: Adenosine Diphosphate; Aged; Aspirin; Clopidogrel; Coronary Disease; Drug Synergism; Drug Therapy, Combination; Dual Specificity Phosphatase 2; Female; Humans; Male; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prospective Studies; Protein Phosphatase 2; Protein Tyrosine Phosphatases; Ticlopidine | 2002 |
Clopidogrel and the CURE results.
Topics: Acute Disease; Aspirin; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2001 |
Clopidogrel treatment before percutaneous coronary intervention reduces adverse cardiac events.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Cost-Benefit Analysis; Drug Therapy, Combination; Female; Humans; Length of Stay; Male; Middle Aged; Platelet Aggregation Inhibitors; Preoperative Care; Ticlopidine; Treatment Outcome | 2002 |
Use of clopidogrel loading, enoxaparin, and double-bolus eptifibatide in the setting of early percutaneous coronary intervention for acute coronary syndromes.
Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Enoxaparin; Eptifibatide; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Peptides; Pilot Projects; Platelet Aggregation Inhibitors; Preoperative Care; Ticlopidine; Treatment Outcome | 2002 |
Effectiveness of clopidogrel and aspirin versus ticlopidine and aspirin after coronary stent implantation: 1 and 6-month follow-up.
Topics: Aged; Aspirin; Blood Vessel Prosthesis Implantation; Clopidogrel; Coronary Stenosis; Drug Therapy, Combination; Female; Follow-Up Studies; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Time Factors | 2001 |
Comparison of antiplatelet effect of loading dose of clopidogrel versus abciximab during coronary intervention.
Topics: Abciximab; Adenosine Diphosphate; Aged; Aged, 80 and over; Angina Pectoris; Antibodies, Monoclonal; Aspirin; Blood Platelets; Clopidogrel; Drug Therapy, Combination; Female; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Stents; Ticlopidine; Treatment Outcome | 2002 |
The effect of clopidogrel in combination with aspirin when given before coronary artery bypass grafting.
Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Bypass; Drug Administration Schedule; Female; Humans; Incidence; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Prospective Studies; Research Design; Ticlopidine; Treatment Outcome | 2002 |
A prospective randomized trial of aspirin-clopidogrel combination therapy and dose-adjusted warfarin on indices of thrombogenesis and platelet activation in atrial fibrillation.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Chronic Disease; Clopidogrel; Cross-Sectional Studies; Drug Therapy, Combination; Female; Fibrin Fibrinogen Degradation Products; Follow-Up Studies; Humans; International Normalized Ratio; Male; Middle Aged; P-Selectin; Peptide Fragments; Platelet Activation; Platelet Aggregation Inhibitors; Prospective Studies; Prothrombin; Ticlopidine; Treatment Outcome; Warfarin | 2002 |
Twelve versus six months of clopidogrel to reduce major cardiac events in patients undergoing gamma-radiation therapy for in-stent restenosis: Washington Radiation for In-Stent restenosis Trial (WRIST) 12 versus WRIST PLUS.
Topics: Aspirin; Brachytherapy; Clopidogrel; Coronary Restenosis; Drug Administration Schedule; Female; Gamma Rays; Graft Occlusion, Vascular; Heart Diseases; Humans; Iridium Radioisotopes; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Registries; Risk; Stents; Ticlopidine; Time; Treatment Outcome | 2002 |
Randomized comparison of cilostazol versus ticlopidine hydrochloride for antiplatelet therapy after coronary stent implantation for prevention of late restenosis.
Topics: Aged; Aspirin; Cilostazol; Coronary Angiography; Coronary Disease; Coronary Restenosis; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Care; Prospective Studies; Research Design; Stents; Tetrazoles; Ticlopidine | 2002 |
Effect of additional temporary glycoprotein IIb/IIIa receptor inhibition on troponin release in elective percutaneous coronary interventions after pretreatment with aspirin and clopidogrel (TOPSTAR trial).
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Disease; Double-Blind Method; Drug Therapy, Combination; Elective Surgical Procedures; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Premedication; Stents; Ticlopidine; Tirofiban; Troponin T; Tyrosine | 2002 |
Amplified benefit of clopidogrel versus aspirin in patients with diabetes mellitus.
Topics: Aged; Aspirin; Clopidogrel; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Endpoint Determination; Female; Follow-Up Studies; Humans; Incidence; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Patient Readmission; Platelet Aggregation Inhibitors; Predictive Value of Tests; Risk Factors; Ticlopidine; Treatment Outcome | 2002 |
Benefit of clopidogrel in patients with acute coronary syndromes without ST-segment elevation in various risk groups.
Topics: Acute Disease; Aged; Aspirin; Clopidogrel; Coronary Disease; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Risk Assessment; Risk Factors; Ticlopidine; Treatment Outcome | 2002 |
Activated clotting times in the setting of eptifibatide use during percutaneous coronary intervention.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Blood Coagulation; Blood Coagulation Tests; Clopidogrel; Drug Therapy, Combination; Eptifibatide; Female; Heparin; Humans; Male; Middle Aged; Peptides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombophilia; Ticlopidine | 2002 |
Effectiveness of clopidogrel versus aspirin in preventing acute myocardial infarction in patients with symptomatic atherothrombosis (CAPRIE trial).
Topics: Age Factors; Aged; Aspirin; Clopidogrel; Creatinine; Diabetes Mellitus; Female; Humans; Male; Massachusetts; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk Factors; Survival Analysis; Thrombosis; Ticlopidine; Treatment Outcome | 2002 |
Clopidogrel does not suppress blood markers of coagulation activation in aspirin-treated patients with non-ST-elevation acute coronary syndromes.
Topics: Antigens; Aspirin; Biomarkers; Blood Coagulation; Blood Coagulation Factors; Clopidogrel; Cohort Studies; Coronary Disease; Drug Therapy, Combination; Female; Fibrin Fibrinogen Degradation Products; Humans; Male; Middle Aged; P-Selectin; Platelet Activating Factor; Platelet Activation; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome; von Willebrand Factor | 2002 |
Early and sustained dual oral antiplatelet therapy following percutaneous coronary intervention: a randomized controlled trial.
Topics: Administration, Oral; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Stroke; Survival Analysis; Thrombosis; Ticlopidine; Treatment Outcome | 2002 |
Effect of antioxidant probucol for preventing stent restenosis.
Topics: Aged; Antioxidants; Aspirin; Blood Vessel Prosthesis Implantation; Coronary Angiography; Coronary Artery Disease; Drug Therapy, Combination; Female; Fibrinolytic Agents; Follow-Up Studies; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Postoperative Complications; Probucol; Stents; Ticlopidine; Time Factors | 2002 |
PFA-100 and flow cytometry: can they challenge aggregometry to assess antiplatelet agents, other than GPIIbIIIa blockers, in coronary angioplasty?
Topics: Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Coronary Disease; Female; Flow Cytometry; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine | 2002 |
Early and late effects of clopidogrel in patients with acute coronary syndromes.
Topics: Acute Disease; Angina, Unstable; Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Hemorrhage; Humans; Kinetics; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Platelet Aggregation Inhibitors; Risk Assessment; Secondary Prevention; Stroke; Syndrome; Ticlopidine; Treatment Outcome | 2003 |
Platelet function under aspirin, clopidogrel, and both after ischemic stroke: a case-crossover study.
Topics: Antigens, CD; Aspirin; Blood Platelets; Brain Ischemia; Case-Control Studies; Clopidogrel; Cross-Over Studies; Drug Therapy, Combination; Female; Flow Cytometry; Humans; Male; Middle Aged; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Secondary Prevention; Stroke; Tetraspanin 30; Ticlopidine | 2003 |
A randomized comparison of clopidogrel and aspirin versus ticlopidine and aspirin after the placement of coronary artery stents.
Topics: Aged; Aspirin; Blood Vessel Prosthesis Implantation; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Stents; Survival Rate; Ticlopidine; Time Factors | 2003 |
Sarpogrelate treatment reduces restenosis after coronary stenting.
Topics: Aged; Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; Cell Division; Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; Drug Therapy, Combination; Female; Fibrinolytic Agents; Follow-Up Studies; Humans; Male; Middle Aged; Muscle, Smooth, Vascular; Prospective Studies; Serotonin Antagonists; Succinates; Ticlopidine; Treatment Outcome | 2003 |
The Clopidogrel in Unstable Angina to Prevent Recurrent Events (CURE) study: to what extent should the results be generalizable?
Topics: Angina, Unstable; Aspirin; Clopidogrel; Coronary Disease; Double-Blind Method; Female; Heart Failure; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Recurrence; Stents; Stroke; Thrombosis; Ticlopidine | 2003 |
A paclitaxel-eluting stent for the prevention of coronary restenosis.
Topics: Angiogenesis Inhibitors; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Disease; Coronary Restenosis; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hyperplasia; Male; Middle Aged; Paclitaxel; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Tunica Intima; Ultrasonography, Interventional | 2003 |
Clopidogrel and aspirin in the prevention of thromboembolic complications after mechanical aortic valve replacement (CAPTA).
Topics: Administration, Oral; Adult; Aged; Aortic Valve; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Heart Valve Prosthesis; Hemorrhage; Humans; Male; Middle Aged; Phenprocoumon; Pilot Projects; Thromboembolism; Ticlopidine; Treatment Outcome | 2003 |
Durability of platelet inhibition by clopidogrel.
Topics: Aged; Aspirin; Clopidogrel; Coronary Disease; Drug Resistance; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Time Factors | 2003 |
Changes in platelet P-selectin and in plasma C-reactive protein in acute atherosclerotic ischemic stroke treated with a loading dose of clopidogrel.
Topics: Aged; Arteriosclerosis; Aspirin; Blood Platelets; Brain Ischemia; C-Reactive Protein; Clopidogrel; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; P-Selectin; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2002 |
Cerebral microembolism is blocked by tirofiban, a selective nonpeptide platelet glycoprotein IIb/IIIa receptor antagonist.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Carotid Artery Diseases; Clopidogrel; Female; Humans; Infusions, Intravenous; Intracranial Embolism; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine; Tirofiban; Treatment Outcome; Tyrosine; Ultrasonography, Doppler, Transcranial | 2003 |
Effects of coadministration of aspirin or clopidogrel on exercise testing in patients with heart failure receiving angiotensin-converting enzyme inhibitors.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Clopidogrel; Cross-Over Studies; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Exercise Test; Heart Failure; Humans; Middle Aged; Oxygen Consumption; Physical Endurance; Platelet Aggregation Inhibitors; Ticlopidine; Time | 2003 |
Clopidogrel for coronary stenting: response variability, drug resistance, and the effect of pretreatment platelet reactivity.
Topics: Adenosine Diphosphate; Aged; Aspirin; Biomarkers; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Resistance; Female; Flow Cytometry; Genetic Variation; Humans; Male; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Stents; Ticlopidine | 2003 |
Aspirin and ticlopidine for prevention of recurrent stroke in black patients: a randomized trial.
Topics: Aged; Aspirin; Black or African American; Double-Blind Method; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Proportional Hazards Models; Recurrence; Stroke; Survival Analysis; Ticlopidine | 2003 |
The effect of a loading dose (300 mg) of clopidogrel on platelet function in patients with peripheral arterial disease.
Topics: Aged; Aspirin; Blood Platelets; Cell Size; Clopidogrel; Drug Resistance; Female; Humans; Male; Middle Aged; Peripheral Vascular Diseases; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Purinergic P2; Serotonin; Ticlopidine | 2003 |
[Non ST elevation acute coronary syndrome. Parameters of fibrinolysis during short term use of ticlopidine or clopidogrel].
Topics: Acute Disease; Adult; Antithrombins; Aspirin; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Female; Fibrinolysis; Humans; Male; Platelet Aggregation Inhibitors; Syndrome; Ticlopidine; Time Factors | 2003 |
[Clopidogrel as adjunctive medication in patients with acute coronary syndrome].
Topics: Aspirin; Clopidogrel; Coronary Disease; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Placebo Effect; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2002 |
Randomized controlled trial of clopidogrel plus aspirin to prevent hemodialysis access graft thrombosis.
Topics: Aged; Aspirin; Catheters, Indwelling; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Platelet Aggregation Inhibitors; Polytetrafluoroethylene; Renal Dialysis; Thrombosis; Ticlopidine | 2003 |
Parameters of the tissue factor pathway with coumadin/dipyridamole versus ticlopidine as adjunct antithrombotic-drug regimen in coronary artery stenting.
Topics: Adult; Angina Pectoris; Angina, Unstable; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Coronary Angiography; Coronary Stenosis; Dipyridamole; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Factor Xa; Female; Follow-Up Studies; Hemorrhage; Heparin; Humans; Lipoproteins; Male; Middle Aged; Statistics as Topic; Stents; Thromboplastin; Thrombosis; Ticlopidine; Time Factors; Warfarin | 2003 |
A comparison of 1-month and 6-month clopidogrel therapy on clinical and angiographic outcome after stent implantation.
Topics: Aged; Aspirin; Clopidogrel; Coronary Angiography; Coronary Disease; Coronary Restenosis; Drug Administration Schedule; Female; Follow-Up Studies; Heparin; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Time Factors; Treatment Outcome | 2003 |
Effects of diltiazem on platelet activation and cytosolic calcium during percutaneous transluminal coronary angioplasty.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Calcium; Calcium Channel Blockers; Coronary Thrombosis; Cytosol; Diltiazem; Drug Therapy, Combination; Female; Humans; Male; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Thromboxane B2; Ticlopidine | 2003 |
Effects of aspirin dose when used alone or in combination with clopidogrel in patients with acute coronary syndromes: observations from the Clopidogrel in Unstable angina to prevent Recurrent Events (CURE) study.
Topics: Acute Disease; Angina, Unstable; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Hemorrhage; Humans; Incidence; Male; Myocardial Infarction; Myocardial Revascularization; Platelet Aggregation Inhibitors; Stroke; Syndrome; Ticlopidine; Treatment Outcome | 2003 |
Evaluation of prolonged antithrombotic pretreatment ("cooling-off" strategy) before intervention in patients with unstable coronary syndromes: a randomized controlled trial.
Topics: Aged; Angina Pectoris; Aspirin; Catheterization; Clopidogrel; Female; Fibrinolytic Agents; Heparin; Humans; Male; Middle Aged; Myocardial Revascularization; Platelet Aggregation Inhibitors; Preoperative Care; Risk; Stents; Ticlopidine; Tirofiban; Treatment Outcome; Troponin T; Tyrosine | 2003 |
Long term prognosis in patients with peripheral arterial disease treated with antiplatelet agents.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cause of Death; Female; Follow-Up Studies; Humans; Intermittent Claudication; Male; Middle Aged; Platelet Aggregation Inhibitors; Prognosis; Risk Factors; Ticlopidine | 2003 |
Ticlopidine alone versus ticlopidine plus aspirin for preventing recurrent stroke.
Topics: Adult; Aged; Aspirin; Cerebral Infarction; Drug Therapy, Combination; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Recurrence; Stroke; Ticlopidine; Treatment Outcome | 2003 |
Triple antiplatelet therapy during percutaneous coronary intervention is associated with improved outcomes including one-year survival: results from the Do Tirofiban and ReoProGive Similar Efficacy Outcome Trial (TARGET).
Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clopidogrel; Combined Modality Therapy; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Immunoglobulin Fab Fragments; Louisiana; Male; Middle Aged; Minnesota; Myocardial Infarction; New York City; Ohio; Pennsylvania; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Postoperative Care; Premedication; Severity of Illness Index; Stents; Survival Analysis; Ticlopidine; Tirofiban; Treatment Outcome; Tyrosine | 2003 |
Managing PAD with multiple platelet inhibitors: the effect of combination therapy on bleeding time.
Topics: Aged; Arterial Occlusive Diseases; Aspirin; Bleeding Time; Cilostazol; Clopidogrel; Drug Therapy, Combination; Female; Humans; Intermittent Claudication; Leg; Male; Platelet Aggregation Inhibitors; Prospective Studies; Tetrazoles; Ticlopidine | 2003 |
Effects of clopidogrel and aspirin combination versus aspirin alone on platelet aggregation and major receptor expression in patients with heart failure: the Plavix Use for Treatment Of Congestive Heart Failure (PLUTO-CHF) trial.
Topics: Aged; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Flow Cytometry; Heart Failure; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Statistics as Topic; Ticlopidine | 2003 |
[Non ST elevation acute coronary syndrome. Some characteristics of coagulation and von Willebrand factor during short term use of ticlopidine or clopidogrel].
Topics: Acute Disease; Adult; Angina, Unstable; Anticoagulants; Aspirin; Blood Coagulation; Clopidogrel; Data Interpretation, Statistical; Electrocardiography; Female; Fibrinolytic Agents; Heparin; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Syndrome; Ticlopidine; Time Factors; Treatment Outcome; von Willebrand Factor | 2003 |
Effects of 2 different antiplatelet regimens with abciximab or tirofiban on platelet function in patients undergoing coronary stenting.
Topics: Abciximab; Antibodies, Monoclonal; Aspirin; Blood Platelets; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Endothelium, Vascular; Female; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; P-Selectin; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Prospective Studies; Stents; Ticlopidine; Tirofiban; Tyrosine | 2003 |
Effects of high ticlopidine doses on platelet function in acute coronary syndrome patients.
Topics: Aspirin; Coronary Disease; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2004 |
Triple antiplatelet therapy does not increase femoral access bleeding with vascular closure devices.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Femoral Artery; Hemorrhage; Hemostasis, Surgical; Heparin; Humans; Male; Middle Aged; Patient Selection; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prospective Studies; Suture Techniques; Ticlopidine | 2004 |
Eptifibatide provides additional platelet inhibition in non-ST-elevation myocardial infarction patients already treated with aspirin and clopidogrel. Results of the platelet activity extinction in non-Q-wave myocardial infarction with aspirin, clopidogrel
Topics: Aged; Aspirin; Clopidogrel; Drug Synergism; Drug Therapy, Combination; Enoxaparin; Eptifibatide; Female; Fibrinogen; Fibrinolytic Agents; Humans; Male; Middle Aged; Myocardial Infarction; Peptides; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine; Treatment Outcome | 2004 |
Serial urinary 11-dehydrothromboxane B2, aspirin dose, and vascular events in blacks after recent cerebral infarction.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Black People; Cerebral Infarction; Dose-Response Relationship, Drug; Double-Blind Method; Drug Resistance; Female; Follow-Up Studies; Humans; Male; Middle Aged; Pilot Projects; Platelet Aggregation Inhibitors; Predictive Value of Tests; Recurrence; Risk Factors; Thromboxane B2; Ticlopidine | 2004 |
Combination antiplatelet therapy in patients with peripheral vascular bypass grafts.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Blood Vessel Prosthesis; Clopidogrel; Drug Therapy, Combination; Female; Flow Cytometry; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Peripheral Vascular Diseases; Platelet Activation; Platelet Aggregation Inhibitors; Ticlopidine | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; Coronary Angiography; Coronary Restenosis; Coronary Stenosis; Coronary Thrombosis; Coronary Vessels; Death, Sudden; Diabetes Mellitus; Disease-Free Survival; Drug Implants; Female; Follow-Up Studies; Humans; Life Tables; Male; Middle Aged; Pilot Projects; Postoperative Complications; Prospective Studies; Safety; Sirolimus; Stents; Survival Analysis; Ticlopidine; Treatment Outcome | 2004 |
Management of atherothrombosis with clopidogrel in high-risk patients with recent transient ischaemic attack or ischaemic stroke (MATCH): study design and baseline data.
Topics: Arteriosclerosis; Aspirin; Clopidogrel; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Thrombosis; Ticlopidine | 2004 |
Clopidogrel plus omeprazole compared with aspirin plus omeprazole for aspirin-induced symptomatic peptic ulcers/erosions with low to moderate bleeding/re-bleeding risk -- a single-blind, randomized controlled study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Aspirin; Clopidogrel; Female; Humans; Male; Middle Aged; Omeprazole; Peptic Ulcer; Peptic Ulcer Hemorrhage; Risk Factors; Single-Blind Method; Ticlopidine | 2004 |
Beneficial effects of clopidogrel combined with aspirin in reducing cerebral emboli in patients undergoing carotid endarterectomy.
Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Disease Progression; Drug Therapy, Combination; Endarterectomy, Carotid; Female; Humans; Intracranial Embolism; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Postoperative Period; Premedication; Risk; Ticlopidine; Treatment Outcome; Ultrasonography, Doppler, Transcranial; Wound Healing | 2004 |
Leukocyte count as an independent predictor of recurrent ischemic events.
Topics: Aspirin; Biomarkers; Brain Ischemia; Cause of Death; Clopidogrel; Female; Humans; Inflammation; Leukocyte Count; Male; Middle Aged; Myocardial Infarction; Peripheral Vascular Diseases; Predictive Value of Tests; Prognosis; Prospective Studies; Recurrence; Risk Factors; Stroke; Ticlopidine | 2004 |
A randomized comparison of clopidogrel and aspirin versus ticlopidine and aspirin after coronary stent implantation.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Stenosis; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2004 |
The Warfarin and Antiplatelet Therapy in Heart Failure trial (WATCH): rationale, design, and baseline patient characteristics.
Topics: Adult; Aged; Anticoagulants; Aspirin; Clopidogrel; Embolism; Female; Heart Failure; Humans; Male; Middle Aged; Patient Selection; Platelet Aggregation Inhibitors; Prospective Studies; Research Design; Ticlopidine; Warfarin | 2004 |
Watching the WATCH trial: the role of sponsors and data monitoring committees.
Topics: Anticoagulants; Aspirin; Clinical Trials Data Monitoring Committees; Clopidogrel; Heart Failure; Humans; Platelet Aggregation Inhibitors; Research Design; Research Support as Topic; Ticlopidine; Warfarin | 2004 |
The effect of clopidogrel, aspirin and both antiplatelet drugs on platelet function in patients with peripheral arterial disease.
Topics: Adenosine Diphosphate; Aged; Arteriosclerosis; Aspirin; Blood Platelets; Cell Shape; Clopidogrel; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; P-Selectin; Peripheral Vascular Diseases; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet-Derived Growth Factor; Serotonin; Ticlopidine | 2004 |
Clopidogrel inhibits platelet-leukocyte interactions and thrombin receptor agonist peptide-induced platelet activation in patients with an acute coronary syndrome.
Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; CD40 Ligand; Clopidogrel; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Humans; Leukocytes; Male; Middle Aged; Myocardial Infarction; P-Selectin; Peptide Fragments; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2004 |
Short-term prevention of thromboembolic complications in patients with atrial fibrillation with aspirin plus clopidogrel: the Clopidogrel-Aspirin Atrial Fibrillation (CLAAF) pilot study.
Topics: Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Bleeding Time; Clopidogrel; Drug Therapy, Combination; Echocardiography, Transesophageal; Electric Countershock; Female; Humans; International Normalized Ratio; Male; Middle Aged; Pilot Projects; Platelet Aggregation Inhibitors; Thromboembolism; Thromboxane B2; Ticlopidine; Warfarin | 2004 |
Comparison of cilostazol and ticlopidine for one-month effectiveness and safety after elective coronary stenting.
Topics: Administration, Oral; Aspirin; Cilostazol; Coronary Restenosis; Coronary Stenosis; Coronary Vessels; Data Collection; Data Interpretation, Statistical; Death; Documentation; Drug Administration Schedule; Drug Therapy, Combination; Elective Surgical Procedures; Evaluation Studies as Topic; Humans; Japan; Medical Records; Myocardial Infarction; Odds Ratio; Stents; Tetrazoles; Ticlopidine; Time Factors; Treatment Outcome | 2004 |
Treatment of left anterior descending coronary artery disease with sirolimus-eluting stents.
Topics: Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Cohort Studies; Coronary Angiography; Coronary Restenosis; Coronary Stenosis; Double-Blind Method; Drug Implants; Female; Humans; Life Tables; Male; Middle Aged; Myocardial Infarction; Premedication; Sirolimus; Stents; Survival Analysis; Ticlopidine; Treatment Outcome; Ultrasonography | 2004 |
Measurement of platelet aggregation during antiplatelet therapy in ischemic stroke.
Topics: Adenosine Diphosphate; Adult; Aspirin; Brain Ischemia; Clopidogrel; Cohort Studies; Collagen; Epinephrine; Female; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Reference Values; Ticlopidine | 2004 |
A randomized crossover comparative study of aspirin, cilostazol and clopidogrel in normal controls: analysis with quantitative bleeding time and platelet aggregation test.
Topics: Adult; Aspirin; Bleeding Time; Cilostazol; Clopidogrel; Cross-Over Studies; Double-Blind Method; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Tetrazoles; Ticlopidine; Time Factors | 2004 |
Loading with 600 mg clopidogrel in patients with coronary artery disease with and without chronic clopidogrel therapy.
Topics: Aged; Aspirin; Blood Platelets; C-Reactive Protein; Clopidogrel; Cohort Studies; Coronary Angiography; Coronary Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Male; Middle Aged; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prospective Studies; Ticlopidine | 2004 |
Clopidogrel added to aspirin versus aspirin alone in secondary prevention and high-risk primary prevention: rationale and design of the Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management, and Avoidance (CHARISMA) trial.
Topics: Arteriosclerosis; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Humans; Middle Aged; Platelet Aggregation Inhibitors; Primary Prevention; Randomized Controlled Trials as Topic; Research Design; Risk Factors; Thrombosis; Ticlopidine | 2004 |
Benefits and risks of the combination of clopidogrel and aspirin in patients undergoing surgical revascularization for non-ST-elevation acute coronary syndrome: the Clopidogrel in Unstable angina to prevent Recurrent ischemic Events (CURE) Trial.
Topics: Acute Disease; Adult; Aged; Angina, Unstable; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Bypass; Double-Blind Method; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation Inhibitors; Risk; Stroke; Ticlopidine; Treatment Outcome | 2004 |
Early statin treatment in patients with acute coronary syndrome: demonstration of the beneficial effect on atherosclerotic lesions by serial volumetric intravascular ultrasound analysis during half a year after coronary event: the ESTABLISH Study.
Topics: Acute Disease; Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Atorvastatin; Cardiovascular Agents; Cholesterol, LDL; Cilostazol; Combined Modality Therapy; Coronary Angiography; Coronary Disease; Female; Follow-Up Studies; Heparin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Pyrroles; Tetrazoles; Ticlopidine; Treatment Outcome; Ultrasonography, Interventional | 2004 |
[First experience of clopidogrel application in the treatment of acute myocardial infarction with ST-elevation].
Topics: Aspirin; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Electrocardiography; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Streptokinase; Ticlopidine; Time Factors; Tissue Plasminogen Activator; Treatment Outcome | 2004 |
The effect of long-term clopidogrel use on neointimal formation after percutaneous coronary intervention.
Topics: Aged; Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Restenosis; Coronary Stenosis; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation Inhibitors; Prosthesis Implantation; Stents; Ticlopidine; Time Factors; Tunica Intima; Ultrasonography, Interventional | 2004 |
Clopidogrel did not inhibit platelet function early after coronary bypass surgery: A prospective randomized trial.
Topics: Aged; Anticoagulants; Aspirin; Clopidogrel; Double-Blind Method; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine | 2004 |
Direct stenting versus direct stenting followed by centered beta-radiation with intravascular ultrasound-guided dosimetry and long-term anti-platelet treatment: results of a randomized trial: Beta-Radiation Investigation with Direct Stenting and Galileo i
Topics: Aged; Aspirin; Brachytherapy; Clopidogrel; Coronary Angiography; Coronary Restenosis; Europe; Female; Humans; Hyperplasia; Male; Middle Aged; Phosphorus Radioisotopes; Platelet Aggregation Inhibitors; Primary Prevention; Radiation Dosage; Stents; Ticlopidine; Tunica Intima; Ultrasonography, Interventional | 2004 |
Magnetic Vascular Port in minimally invasive direct coronary artery bypass grafting.
Topics: Aged; Aspirin; Clopidogrel; Comorbidity; Coronary Angiography; Drug Therapy, Combination; Equipment Design; Female; Follow-Up Studies; Humans; Internal Mammary-Coronary Artery Anastomosis; Magnetics; Male; Middle Aged; Minimally Invasive Surgical Procedures; Platelet Aggregation Inhibitors; Postoperative Complications; Prospective Studies; Surgical Instruments; Thrombosis; Ticlopidine; Treatment Outcome; Vascular Patency | 2004 |
[Dysaggregants effect of platelet aggregation in patients with non-ST segment elevation acute coronary syndrome].
Topics: Acute Disease; Aspirin; Blood Platelets; Clopidogrel; Coronary Disease; Electrocardiography; Female; Humans; Male; Nadroparin; Platelet Aggregation Inhibitors; Syndrome; Ticlopidine | 2004 |
Comparative effect of antiplatelet therapy in retinal vein occlusion evaluated by the particle-counting method using light scattering.
Topics: Aged; Aspirin; Epoprostenol; Female; Humans; Light; Male; Middle Aged; Particle Size; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Retinal Vein Occlusion; Scattering, Radiation; Ticlopidine | 2004 |
A randomized comparison of the effects of aspirin and clopidogrel on thrombotic risk factors and C-reactive protein following myocardial infarction: the CADET trial.
Topics: Aged; Aspirin; Biomarkers; Blood Coagulation Factors; Blood Viscosity; C-Reactive Protein; Clopidogrel; Double-Blind Method; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk Factors; Thrombosis; Ticlopidine | 2004 |
Variable extent of clopidogrel responsiveness in patients after coronary stenting.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; Cell Adhesion Molecules; Clopidogrel; Drug Therapy, Combination; Female; Flow Cytometry; GTP-Binding Protein alpha Subunits, Gi-Go; Heart Diseases; Humans; Male; Membrane Proteins; Microfilament Proteins; Middle Aged; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Stents; Ticlopidine; Treatment Outcome | 2004 |
Quantitative assessment of angiographic restenosis after sirolimus-eluting stent implantation in native coronary arteries.
Topics: Aged; Aspirin; Clopidogrel; Coronary Aneurysm; Coronary Angiography; Coronary Restenosis; Coronary Stenosis; Diabetes Complications; Double-Blind Method; Drug Implants; Drug Therapy, Combination; Female; Follow-Up Studies; Heparin; Humans; Incidence; Male; Middle Aged; Randomized Controlled Trials as Topic; Sirolimus; Stents; Ticlopidine; Treatment Outcome | 2004 |
Randomized clinical trial of the antiplatelet effects of aspirin-clopidogrel combination versus aspirin alone after lower limb angioplasty.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Endarterectomy; Female; Fibrinogen; Flow Cytometry; Humans; Intermittent Claudication; Leg; Male; Middle Aged; P-Selectin; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2005 |
Does pre-treatment with aspirin and loading dose clopidogrel obviate the need for glycoprotein IIb/IIIa antagonists during elective coronary stenting? A focus on peri-procedural myonecrosis.
Topics: Abciximab; Aged; Antibodies, Monoclonal; Aspirin; Clopidogrel; Coronary Angiography; Coronary Disease; Creatine Kinase; Creatine Kinase, MB Form; Female; Follow-Up Studies; Humans; Immunoglobulin Fab Fragments; Isoenzymes; Logistic Models; Male; Middle Aged; Neovascularization, Pathologic; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Premedication; Recurrence; Stents; Survival Rate; Thrombosis; Ticlopidine; Troponin T | 2005 |
Clopidogrel versus aspirin and esomeprazole to prevent recurrent ulcer bleeding.
Topics: Aged; Anti-Ulcer Agents; Aspirin; Cardiovascular Diseases; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Esomeprazole; Female; Humans; Male; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Prospective Studies; Proton Pump Inhibitors; Secondary Prevention; Ticlopidine | 2005 |
Enhanced antiplatelet effects of clopidogrel plus acetylsalicylic acid compared with acetylsalicylic acid alone or combined with extended-release dipyridamole in healthy volunteers.
Topics: Adult; Arachidonic Acid; Aspirin; Blood Platelets; Clopidogrel; Collagen; Cross-Over Studies; Delayed-Action Preparations; Dipyridamole; Drug Therapy, Combination; Humans; In Vitro Techniques; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2005 |
Effects of aspirin, clopidogrel and dipyridamole administered singly and in combination on platelet and leucocyte function in normal volunteers and patients with prior ischaemic stroke.
Topics: Adult; Aged; Aspirin; Blood Platelets; Brain Ischemia; Case-Control Studies; Cell Adhesion; Clopidogrel; Cross-Over Studies; Dipyridamole; Drug Therapy, Combination; Female; Humans; Leukocytes; Male; Middle Aged; Platelet Aggregation; Stroke; Ticlopidine | 2005 |
Starc II, a multicenter randomized placebo-controlled double-blind clinical trial of trapidil for 1-year clinical events and angiographic restenosis reduction after coronary angioplasty and stenting.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Blood Vessel Prosthesis Implantation; Coronary Angiography; Coronary Restenosis; Double-Blind Method; Female; Follow-Up Studies; Humans; Incidence; Male; Middle Aged; Myocardial Ischemia; Patient Compliance; Platelet Aggregation Inhibitors; Safety; Stents; Ticlopidine; Trapidil; Treatment Failure; Treatment Outcome | 2005 |
Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation.
Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Drug Therapy, Combination; Electrocardiography; Female; Fibrinolytic Agents; Hemorrhage; Heparin; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Secondary Prevention; Thrombolytic Therapy; Ticlopidine; Vascular Patency | 2005 |
What is the risk of stent thrombosis associated with the use of paclitaxel-eluting stents for percutaneous coronary intervention?: a meta-analysis.
Topics: Aged; Angioplasty, Balloon, Coronary; Antineoplastic Agents, Phytogenic; Aspirin; Blood Vessel Prosthesis Implantation; Clopidogrel; Coated Materials, Biocompatible; Coronary Artery Disease; Coronary Thrombosis; Female; Humans; Male; Middle Aged; Paclitaxel; Platelet Aggregation Inhibitors; Postoperative Complications; Risk Factors; Stents; Ticlopidine; Treatment Outcome | 2005 |
Comparison of cilostazol and clopidogrel after successful coronary stenting.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Clopidogrel; Coronary Restenosis; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Prospective Studies; Stents; Tetrazoles; Thrombosis; Ticlopidine; Treatment Outcome | 2005 |
Monitoring of clopidogrel action: comparison of methods.
Topics: Adult; Aspirin; Biomarkers; Bleeding Time; Cell Adhesion Molecules; Clopidogrel; Drug Monitoring; Female; Flow Cytometry; Humans; Immunoenzyme Techniques; In Vitro Techniques; Male; Microfilament Proteins; P-Selectin; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors | 2005 |
[Safety and efficacy of dalteparin administration for elective percutaneous interventions in patients pre-treated with aspirin and ticlopidine].
Topics: Adolescent; Adult; Aged; Angioplasty, Balloon; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dalteparin; Double-Blind Method; Drug Therapy, Combination; Elective Surgical Procedures; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Preoperative Care; Prospective Studies; Survival Rate; Ticlopidine | 2004 |
Dual antiplatelet therapy with clopidogrel and aspirin in symptomatic carotid stenosis evaluated using doppler embolic signal detection: the Clopidogrel and Aspirin for Reduction of Emboli in Symptomatic Carotid Stenosis (CARESS) trial.
Topics: Aged; Aspirin; Carotid Stenosis; Clopidogrel; Drug Monitoring; Drug Therapy, Combination; Embolism; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Ultrasonography, Doppler, Transcranial | 2005 |
Comparative inhibitory effects of cilostazol and ticlopidine on subacute stent thrombosis and platelet function in acute myocardial infarction patients with percutaneous coronary intervention.
Topics: Aged; Aspirin; Cilostazol; Drug Therapy, Combination; Female; Humans; Incidence; Male; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Retrospective Studies; Stents; Tetrazoles; Thrombosis; Ticlopidine | 2005 |
The benefits of combined anti-platelet treatment in carotid artery stenting.
Topics: Aged; Aged, 80 and over; Aspirin; Carotid Stenosis; Clopidogrel; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Stents; Ticlopidine | 2005 |
Comparison of two strategies for the management of antiplatelet therapy during urgent surgery.
Topics: Aged; Angina, Unstable; Aprotinin; Aspirin; Clopidogrel; Coronary Artery Bypass; Female; Hemostatics; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine | 2005 |
Effect of clopidogrel plus aspirin on tissue perfusion and coronary flow in patients with ST-segment elevation myocardial infarction: a new reperfusion strategy.
Topics: Aged; Aspirin; Clopidogrel; Coronary Circulation; Drug Therapy, Combination; Electrocardiography; Female; Humans; Male; Middle Aged; Myocardial Infarction; Regional Blood Flow; Ticlopidine | 2005 |
Prospective randomized comparison of early and late results of a carbonized stent versus a high-grade stainless steel stent of identical design: the PREVENT Trial [corrected].
Topics: Adult; Aged; Angina, Unstable; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Biocompatible Materials; Carbon; Clopidogrel; Combined Modality Therapy; Coronary Angiography; Coronary Disease; Coronary Restenosis; Equipment Design; Female; Heparin; Humans; Male; Materials Testing; Middle Aged; Prospective Studies; Recurrence; Stainless Steel; Stents; Thromboembolism; Thrombophilia; Ticlopidine; Time Factors; Treatment Outcome; Venous Thrombosis | 2005 |
Superior efficacy of clopidogrel plus acetylsalicylic acid compared with extended-release dipyridamole plus acetylsalicylic acid in preventing arterial thrombogenesis in healthy volunteers.
Topics: Adolescent; Adult; Arteries; Aspirin; Clopidogrel; Collagen; Cross-Over Studies; Delayed-Action Preparations; Dipyridamole; Drug Therapy, Combination; Fibrin; Humans; Immunoenzyme Techniques; Male; Perfusion; Platelet Adhesiveness; Platelet Function Tests; Thrombosis; Ticlopidine | 2005 |
Matching the evaluation of the clinical efficacy of clopidogrel to platelet function tests relevant to the biological properties of the drug.
Topics: Aged; Angina Pectoris; Anticoagulants; Aspirin; Blood Platelets; Case-Control Studies; Clopidogrel; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine; Time Factors; Treatment Outcome | 2005 |
Clopidogrel has no effect on D-dimer and thrombin-antithrombin III levels in patients with peripheral arterial disease undergoing peripheral percutaneous transluminal angioplasty.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angioplasty, Balloon; Anti-Inflammatory Agents, Non-Steroidal; Antithrombin III; Aspirin; Clopidogrel; Double-Blind Method; Female; Fibrin Fibrinogen Degradation Products; Humans; Intermittent Claudication; Male; Middle Aged; Peptide Hydrolases; Platelet Aggregation Inhibitors; Ticlopidine | 2005 |
Clopidogrel and bleeding after coronary artery bypass graft surgery.
Topics: Aged; Aspirin; Blood Transfusion; Blood Volume; Clopidogrel; Coronary Artery Bypass; Drug Therapy, Combination; Female; Humans; Intensive Care Units; Length of Stay; Male; Middle Aged; Outcome and Process Assessment, Health Care; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Preoperative Care; Prospective Studies; Ticlopidine | 2005 |
Long-term cost effectiveness of early and sustained dual oral antiplatelet therapy with clopidogrel given for up to one year after percutaneous coronary intervention results: from the Clopidogrel for the Reduction of Events During Observation (CREDO) tria
Topics: Aspirin; Cardiac Catheterization; Clopidogrel; Cost-Benefit Analysis; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Time Factors; Treatment Outcome | 2005 |
Effect of clopidogrel pretreatment before percutaneous coronary intervention in patients with ST-elevation myocardial infarction treated with fibrinolytics: the PCI-CLARITY study.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Thrombolytic Therapy; Ticlopidine | 2005 |
Effects of clopidogrel and aspirin in combination versus aspirin alone on platelet activation and major receptor expression in patients after recent ischemic stroke: for the Plavix Use for Treatment of Stroke (PLUTO-Stroke) trial.
Topics: Aged; Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biomarkers; Blood Platelets; Brain Ischemia; Clopidogrel; Drug Therapy, Combination; Female; Flow Cytometry; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Stroke; Ticlopidine; Time Factors; Tomography, X-Ray Computed | 2005 |
Relation of aspirin resistance to coronary flow reserve in patients undergoing elective percutaneous coronary intervention.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Circulation; Drug Resistance; Female; Humans; Linear Models; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2005 |
A randomized, double-blind, placebo-controlled trial of abciximab for prevention of in-stent restenosis in diabetic patients after coronary stenting: results of the ASIAD (Abciximab in Stenting Inhibits restenosis Among Diabetics) Trial.
Topics: Abciximab; Antibodies, Monoclonal; Aspirin; Blood Coagulation; Clopidogrel; Coronary Angiography; Coronary Disease; Coronary Restenosis; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Follow-Up Studies; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prospective Studies; Stents; Ticlopidine | 2005 |
Impact of heparin neutralization by protamine on restenosis after coronary stent implantation.
Topics: Aged; Angina Pectoris; Anticoagulants; Aspirin; Blood Vessel Prosthesis Implantation; Coronary Restenosis; Female; Heparin; Heparin Antagonists; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Protamines; Stents; Ticlopidine; Treatment Outcome | 2005 |
Variability in platelet aggregation following sustained aspirin and clopidogrel treatment in patients with coronary heart disease and influence of the 807 C/T polymorphism of the glycoprotein Ia gene.
Topics: Adult; Alleles; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Coronary Disease; Epinephrine; Female; Humans; Integrin alpha2; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Ticlopidine | 2005 |
Addition of clopidogrel to aspirin in 45,852 patients with acute myocardial infarction: randomised placebo-controlled trial.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; China; Clopidogrel; Drug Therapy, Combination; Electrocardiography; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2005 |
Aspirin, warfarin and a thienopyridine for acute coronary syndromes.
Topics: Aspirin; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Female; Hematologic Agents; Humans; Male; Pyridines; Risk Factors; Syndrome; Ticlopidine; Ventricular Function; Warfarin | 2006 |
Angiographic and clinical outcomes in patients receiving low-molecular-weight heparin versus unfractionated heparin in ST-elevation myocardial infarction treated with fibrinolytics in the CLARITY-TIMI 28 Trial.
Topics: Adolescent; Adult; Aged; Aspirin; Clopidogrel; Coronary Angiography; Coronary Thrombosis; Drug Therapy, Combination; Electrocardiography; Female; Fibrinolytic Agents; Hemorrhage; Heparin; Heparin, Low-Molecular-Weight; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Reperfusion; Secondary Prevention; Ticlopidine; Treatment Outcome; Vascular Patency | 2005 |
[Effects of cilostazol on long-term clinical outcomes after coronary stenting].
Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Coronary Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Stents; Tetrazoles; Ticlopidine; Treatment Outcome | 2005 |
Comparative effect of aspirin and clopidogrel on arterial function in CHF.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Chi-Square Distribution; Clopidogrel; Double-Blind Method; Female; Heart Failure; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine | 2006 |
Antiplatelets in stroke prevention: the MATCH trial. Some answers, many questions and countless perspectives.
Topics: Age Factors; Aged; Aspirin; Cerebrovascular Disorders; Clopidogrel; Drug Therapy, Combination; Female; Hemorrhage; Humans; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Secondary Prevention; Stroke; Ticlopidine; Treatment Outcome | 2005 |
[Indirect comparison of changes of parameters of hemostasis during short-term use of ticlopidine and clopidogrel in patients with non-ST elevation acute coronary syndrome].
Topics: Anticoagulants; Aspirin; Clopidogrel; Electrocardiography; Enoxaparin; Fibrinolysis; Fibrinolytic Agents; Hemostasis; Heparin; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Syndrome; Thrombin; Ticlopidine; Time Factors | 2005 |
Enhanced antiplatelet effect of clopidogrel in patients whose platelets are least inhibited by aspirin: a randomized crossover trial.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Biomarkers; Clopidogrel; Collagen; Cross-Over Studies; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Nephelometry and Turbidimetry; Peripheral Vascular Diseases; Platelet Activation; Platelet Aggregation Inhibitors; Ticlopidine | 2005 |
High post-treatment platelet reactivity identified low-responders to dual antiplatelet therapy at increased risk of recurrent cardiovascular events after stenting for acute coronary syndrome.
Topics: Acute Disease; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Premedication; Prospective Studies; Risk Factors; Secondary Prevention; Stents; Syndrome; Ticlopidine; Treatment Outcome | 2006 |
Anti-thrombotic action of clopidogrel and P1(A1/A2) polymorphism of beta3 integrin in patients with coronary artery disease not being treated with aspirin.
Topics: Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Genotype; Humans; Integrin beta3; Male; P-Selectin; Peptide Fragments; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Polymorphism, Genetic; Prothrombin; Thrombosis; Ticlopidine; Time Factors | 2005 |
Effect of aspirin, clopidogrel and dipyridamole on soluble markers of vascular function in normal volunteers and patients with prior ischaemic stroke.
Topics: Adult; Arteriosclerosis; Aspirin; Biomarkers; Blood Platelets; Brain Ischemia; C-Reactive Protein; Clopidogrel; Cross-Sectional Studies; Dipyridamole; Double-Blind Method; Drug Therapy, Combination; Endothelium, Vascular; Female; Humans; Male; Middle Aged; Plasminogen Activator Inhibitor 1; Platelet Count; Platelet-Derived Growth Factor; Solubility; Stroke; Ticlopidine; Treatment Outcome; von Willebrand Factor | 2006 |
Effect of combined administration of clopidogrel and lysine acetylsalicylate versus clopidogrel and aspirin on platelet aggregation and activated GPIIb/IIIa expression in healthy volunteers.
Topics: Adult; Aspirin; Blood Platelets; Clopidogrel; Drug Therapy, Combination; Female; Humans; Lysine; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Reference Values; Ticlopidine | 2006 |
Effect of aspirin plus clopidogrel on inflammatory markers in patients with non-ST-segment elevation acute coronary syndrome.
Topics: Adult; Aged; Angina, Unstable; Aspirin; C-Reactive Protein; Clopidogrel; Drug Therapy, Combination; Electrocardiography; Female; Humans; Inflammation; Male; Middle Aged; Myocardial Infarction; Ticlopidine; Tumor Necrosis Factor-alpha | 2006 |
Effect of platelet antigen polymorphism on platelet inhibition by aspirin, clopidogrel, or their combination.
Topics: Adenosine Diphosphate; Antigens, Human Platelet; Aspirin; Blood Platelets; Clopidogrel; Collagen; Coronary Artery Disease; Cytoplasmic Granules; Epinephrine; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Polymorphism, Genetic; Ticlopidine | 2006 |
Pharmacodynamics, pharmacokinetics, and safety of the oral reversible P2Y12 antagonist AZD6140 with aspirin in patients with atherosclerosis: a double-blind comparison to clopidogrel with aspirin.
Topics: Adenosine; Administration, Oral; Adult; Aged; Aged, 80 and over; Aspirin; Atherosclerosis; Bleeding Time; Clopidogrel; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Postmenopause; Ticagrelor; Ticlopidine | 2006 |
A study of aspirin and clopidogrel in idiopathic pulmonary arterial hypertension.
Topics: Adult; Aspirin; Clopidogrel; Cross-Over Studies; Double-Blind Method; Female; Humans; Hypertension, Pulmonary; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane A2; Ticlopidine | 2006 |
Antithrombotic effects of ximelagatran plus acetylsalicylic acid (ASA) and clopidogrel plus ASA in a human ex vivo arterial thrombosis model.
Topics: Administration, Oral; Adult; Anticoagulants; Arteries; Aspirin; Azetidines; Benzylamines; Bleeding Time; Blood Coagulation; Clopidogrel; Dose-Response Relationship, Drug; Fibrinolytic Agents; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombin; Thrombosis; Ticlopidine | 2006 |
Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Clopidogrel; Data Interpretation, Statistical; Double-Blind Method; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Proportional Hazards Models; Prospective Studies; Risk Factors; Stroke; Thrombosis; Ticlopidine | 2006 |
Can clopidogrel and aspirin lower mortality in patients with acute myocardial infarction?
Topics: Aged; Aspirin; Clopidogrel; Confidence Intervals; Dose-Response Relationship, Drug; Drug Administration Schedule; Electrocardiography; Emergency Medical Services; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Probability; Severity of Illness Index; Survival Rate; Ticlopidine; Treatment Outcome | 2006 |
Genetic polymorphisms of the platelet receptors P2Y(12), P2Y(1) and GP IIIa and response to aspirin and clopidogrel.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Female; Humans; Integrin beta3; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Ticlopidine | 2007 |
Prasugrel achieves greater inhibition of platelet aggregation and a lower rate of non-responders compared with clopidogrel in aspirin-treated patients with stable coronary artery disease.
Topics: Adult; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Ticlopidine | 2006 |
Biological effects of aspirin and clopidogrel in a randomized cross-over study in 96 healthy volunteers.
Topics: Adolescent; Adult; Aspirin; Blood Coagulation Tests; Clopidogrel; Cross-Over Studies; Dose-Response Relationship, Drug; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Thromboxane B2; Ticlopidine; Treatment Outcome | 2006 |
Clopidogrel improves systemic endothelial nitric oxide bioavailability in patients with coronary artery disease: evidence for antioxidant and antiinflammatory effects.
Topics: Acetylcholine; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Biological Availability; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Endothelium, Vascular; Enzyme Inhibitors; Humans; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Ticlopidine; Vasodilation; Vasodilator Agents | 2006 |
A comparison of dual vs. triple antiplatelet therapy in patients with non-ST-segment elevation acute coronary syndrome: results of the ELISA-2 trial.
Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Drug Combinations; Enzymes; Female; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine; Tirofiban; Treatment Outcome; Tyrosine | 2006 |
Overcoming aspirin resistance: increased platelet inhibition with combination aspirin and clopidogrel and high dose aspirin therapy in aspirin resistant patients with peripheral vascular disease.
Topics: Aged; Aged, 80 and over; Arterial Occlusive Diseases; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2006 |
A comparison of pharmacologic therapy with/without timely coronary intervention vs. primary percutaneous intervention early after ST-elevation myocardial infarction: the WEST (Which Early ST-elevation myocardial infarction Therapy) study.
Topics: Abciximab; Aged; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clopidogrel; Drug Therapy, Combination; Enoxaparin; Feasibility Studies; Female; Fibrinolytic Agents; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Myocardial Infarction; Myocardial Reperfusion; Platelet Aggregation Inhibitors; Tenecteplase; Thrombolytic Therapy; Ticlopidine; Tissue Plasminogen Activator | 2006 |
Clopidogrel plus aspirin versus oral anticoagulation for atrial fibrillation in the Atrial fibrillation Clopidogrel Trial with Irbesartan for prevention of Vascular Events (ACTIVE W): a randomised controlled trial.
Topics: Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Biphenyl Compounds; Clopidogrel; Drug Therapy, Combination; Humans; International Normalized Ratio; Irbesartan; Platelet Aggregation Inhibitors; Risk Factors; Severity of Illness Index; Stroke; Tetrazoles; Ticlopidine | 2006 |
[Short-term outcomes of triple antiplatelet therapy after percutaneous coronary intervention].
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Period; Retrospective Studies; Tetrazoles; Ticlopidine; Time Factors; Treatment Outcome | 2006 |
Esomeprazole with aspirin versus clopidogrel for prevention of recurrent gastrointestinal ulcer complications.
Topics: Aged; Aged, 80 and over; Anti-Ulcer Agents; Aspirin; Clopidogrel; Cohort Studies; Double-Blind Method; Esomeprazole; Female; Humans; Male; Middle Aged; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Secondary Prevention; Stomach Ulcer; Ticlopidine; Treatment Outcome | 2006 |
Delayed thrombin-induced platelet-fibrin clot generation by clopidogrel: a new dose-related effect demonstrated by thrombelastography in patients undergoing coronary artery stenting.
Topics: Aged; Anticoagulants; Aspirin; Blood Coagulation; Clopidogrel; Coronary Stenosis; Dose-Response Relationship, Drug; Female; Humans; Male; Platelet Aggregation; Reproducibility of Results; Stents; Thrombelastography; Thrombin; Ticlopidine; Time Factors; Treatment Outcome | 2007 |
Angiographically evident thrombus following fibrinolytic therapy is associated with impaired myocardial perfusion in STEMI: a CLARITY-TIMI 28 substudy.
Topics: Adolescent; Adult; Aged; Aspirin; Clopidogrel; Coronary Angiography; Coronary Thrombosis; Double-Blind Method; Drug Combinations; Fibrinolytic Agents; Humans; Microcirculation; Middle Aged; Myocardial Infarction; Myocardial Reperfusion; Ticlopidine | 2006 |
Randomized comparison of the effects of ASA plus clopidogrel versus ASA alone on early platelet activation in acute coronary syndromes with elevated high-sensitivity C-reactive protein and soluble CD40 ligand levels.
Topics: Acute Disease; Aged; Angina, Unstable; Aspirin; C-Reactive Protein; CD40 Ligand; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Male; Myocardial Infarction; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Risk Factors; Single-Blind Method; Syndrome; Ticlopidine | 2006 |
Erythrocyte deformability and white blood cell count are associated with aspirin resistance in high-risk vascular patients.
Topics: Aged; Angina, Unstable; Aspirin; Bleeding Time; Blood Viscosity; Clopidogrel; Drug Resistance; Erythrocyte Deformability; Female; Hemorheology; Humans; Leukocyte Count; Leukocytes; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine | 2006 |
Clopidogrel is associated with a lesser increase in NT-proBNP when compared to aspirin in patients with ischemic heart failure.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiac Output, Low; Clopidogrel; Cross-Over Studies; Disease Progression; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Natriuretic Peptide, Brain; Peptide Fragments; Platelet Aggregation Inhibitors; Ticlopidine | 2006 |
Effects of aspirin and clopidogrel on plasma brain natriuretic peptide in patients with heart failure receiving ACE inhibitors.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Aspirin; Clopidogrel; Female; Heart Failure; Humans; Male; Middle Aged; Natriuretic Peptide, Brain; Prostaglandins; Ticlopidine | 2007 |
Diabetes mellitus and platelet function after administration of aspirin and a single 600 mg dose of clopidogrel.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Clopidogrel; Collagen; Coronary Artery Disease; Diabetes Complications; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Male; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Receptors, Thrombin; Thrombosis; Ticlopidine | 2006 |
Aspirin in peripheral arterial disease: breakthrough or pitfall?
Topics: Arterial Occlusive Diseases; Aspirin; Clopidogrel; Collateral Circulation; Combined Modality Therapy; Contraindications; Double-Blind Method; Exercise Test; Germany; Humans; Intermittent Claudication; Neovascularization, Physiologic; Physical Therapy Modalities; Platelet Aggregation Inhibitors; Prospective Studies; Switzerland; Ticlopidine | 2006 |
Recombinant factor VIIa reverses the inhibitory effect of aspirin or aspirin plus clopidogrel on in vitro thrombin generation.
Topics: Adult; Aged; Aspirin; Blood Coagulation Tests; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Factor VIIa; Female; Humans; Male; Middle Aged; Platelet Activation; Platelet Function Tests; Recombinant Proteins; Thrombin; Ticlopidine | 2006 |
Thromboelastography: potential bedside tool to assess the effects of antiplatelet therapy?
Topics: Adult; Aspirin; Blood Platelets; Clopidogrel; Female; Humans; Male; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Thrombelastography; Thrombosis; Ticlopidine; Time Factors | 2006 |
Evidence that pre-existent variability in platelet response to ADP accounts for 'clopidogrel resistance'.
Topics: Adenosine Diphosphate; Adult; Aspirin; Bayes Theorem; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Drug Resistance; Female; Humans; Male; Middle Aged; Models, Cardiovascular; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Reference Values; Severity of Illness Index; Ticlopidine; Time Factors | 2007 |
Quantifying the effect of antiplatelet therapy: a comparison of the platelet function analyzer (PFA-100) and modified thromboelastography (mTEG) with light transmission platelet aggregometry.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Atorvastatin; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Light; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Pyrroles; Surgical Procedures, Operative; Thrombelastography; Ticlopidine | 2006 |
The role of aspirin resistance on outcome in patients with acute coronary syndrome and the effect of clopidogrel therapy in the prevention of major cardiovascular events.
Topics: Angina, Unstable; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Resistance; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Prospective Studies; Ticlopidine; Treatment Outcome | 2006 |
[The effects of post coronary stenting triple antiplatelet therapies on platelet functions].
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Coronary Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Stents; Tetrazoles; Ticlopidine | 2006 |
No difference in the effects of clopidogrel and aspirin on inflammatory markers in patients with coronary heart disease.
Topics: Aspirin; Biomarkers; Chemokine CCL2; Clopidogrel; Coronary Disease; Humans; Inflammation; Ticlopidine; Time Factors; Tumor Necrosis Factor-alpha | 2006 |
[Prevention of atherothrombotic incidents. CHARISMA Study (The Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management and Avoidance].
Topics: Aged; Aspirin; Cause of Death; Clopidogrel; Coronary Thrombosis; Drug Therapy, Combination; Embolism, Cholesterol; Female; Humans; Intracranial Embolism; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine | 2006 |
Efficacy and safety of clopidogrel 600 mg administered pre-hospitally to improve primary percutaneous coronary intervention in patients with acute myocardial infarction (CIPAMI): study rationale and design.
Topics: Adult; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Drug Administration Schedule; Enoxaparin; Heparin; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Prospective Studies; Research Design; Ticlopidine; Treatment Outcome | 2007 |
Effect of antiplatelet agents clopidogrel, aspirin, and cilostazol on circulating tissue factor procoagulant activity in patients with peripheral arterial disease.
Topics: Aged; Aged, 80 and over; Antithrombin III; Aspirin; Blood Platelets; C-Reactive Protein; CD40 Ligand; Cell Membrane; Cilostazol; Clopidogrel; Down-Regulation; Drug Therapy, Combination; Factor VIIa; Humans; Middle Aged; P-Selectin; Peptide Fragments; Peptide Hydrolases; Peripheral Vascular Diseases; Pilot Projects; Platelet Aggregation Inhibitors; Prospective Studies; Prothrombin; Tetrazoles; Thromboplastin; Ticlopidine | 2006 |
Naproxen treatment prevents periprocedural inflammatory response but not myocardial injury after percutaneous coronary intervention.
Topics: Aged; Angioplasty, Balloon, Coronary; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; C-Reactive Protein; Clopidogrel; Creatine Kinase, MB Form; Drug Combinations; Female; Follow-Up Studies; Humans; Inflammation; Intraoperative Period; Male; Middle Aged; Myocardial Infarction; Naproxen; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors; Treatment Outcome; Troponin I | 2007 |
Prehospital fibrinolysis with dual antiplatelet therapy in ST-elevation acute myocardial infarction: a substudy of the randomized double blind CLARITY-TIMI 28 trial.
Topics: Aged; Ambulances; Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Emergency Medical Services; Female; Fibrinolysis; Hemorrhage; Heparin; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Thrombolytic Therapy; Ticlopidine; Treatment Outcome | 2007 |
Normalization of platelet reactivity in clopidogrel-treated subjects.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Aspirin; Blood Platelets; Clopidogrel; Collagen; Coronary Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fibrinogen; Humans; Male; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Transfusion; Platelet-Rich Plasma; Postoperative Hemorrhage; Receptors, Thrombin; Recovery of Function; Reference Values; Ticlopidine; Time Factors | 2007 |
Effect of atorvastatin and pravastatin on platelet inhibition by aspirin and clopidogrel treatment in patients with coronary stent thrombosis.
Topics: Aged; Aspirin; Atorvastatin; Clopidogrel; Coronary Restenosis; Drug Interactions; Drug Therapy, Combination; Electrocardiography; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Pravastatin; Prospective Studies; Prosthesis Failure; Pyrroles; Stents; Ticlopidine; Treatment Outcome | 2007 |
Lack of association between the 807 C/T polymorphism of glycoprotein Ia gene and post-treatment platelet reactivity after aspirin and clopidogrel in patients with acute coronary syndrome.
Topics: Acute Disease; Adenosine Diphosphate; Aged; Aspirin; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Cytosine; Female; France; Genotype; Humans; Integrin alpha2; Male; Microfilament Proteins; Middle Aged; Myocardial Ischemia; P-Selectin; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Single Nucleotide; Prospective Studies; Syndrome; Thymine; Ticlopidine; Treatment Outcome | 2007 |
Response to aspirin and clopidogrel in patients scheduled to undergo cardiovascular surgery.
Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Bypass; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Count; Preoperative Care; Ticlopidine; Treatment Outcome | 2007 |
Clinical relevance of aspirin resistance in patients with stable coronary artery disease: a prospective follow-up study (PROSPECTAR).
Topics: Aged; Angina Pectoris; Aspirin; Clopidogrel; Coronary Artery Disease; Death; Drug Resistance; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation; Platelet Function Tests; Prevalence; Stroke; Survival Analysis; Ticlopidine; Treatment Outcome | 2007 |
Rationale, design and baseline data of a randomized, double-blind, controlled trial comparing two antithrombotic regimens (a fixed-dose combination of extended-release dipyridamole plus ASA with clopidogrel) and telmisartan versus placebo in patients with
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Benzimidazoles; Benzoates; Clopidogrel; Delayed-Action Preparations; Dipyridamole; Double-Blind Method; Drug Combinations; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Research Design; Secondary Prevention; Stroke; Telmisartan; Ticlopidine; Treatment Outcome | 2007 |
[Influence of the double antiplatelet therapy on patency of the occluded artery after acute myocardial infarction with ST-segment elevation].
Topics: Adult; Aged; Aspirin; Clopidogrel; Coronary Angiography; Drug Therapy, Combination; Electrocardiography; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Thrombolytic Therapy; Ticlopidine; Vascular Patency | 2007 |
Relation between impaired antiplatelet response to clopidogrel and possible pleiotropic effects.
Topics: Aged; Aspirin; Blood Platelets; C-Reactive Protein; Clopidogrel; Drug Resistance; Female; Humans; Inflammation; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Function Tests; Stents; Ticlopidine | 2007 |
Dose-dependent inhibition of human platelet aggregation by prasugrel and its interaction with aspirin in healthy subjects.
Topics: Adenosine Diphosphate; Adolescent; Adult; Aspirin; Bleeding Time; Clopidogrel; Collagen; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Middle Aged; Peptide Fragments; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Ticlopidine | 2007 |
Safety of sirolimus-eluting stenting and its effect on restenosis in patients with unstable angina pectoris (a SIRIUS substudy).
Topics: Angina, Unstable; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Restenosis; Double-Blind Method; Female; Fibrinolytic Agents; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Retreatment; Retrospective Studies; Safety; Sirolimus; Stents; Survival Rate; Ticlopidine; Time Factors; Treatment Outcome | 2007 |
Comparison of two antiplatelet regimens (aspirin alone versus aspirin + ticlopidine or clopidogrel) after intracoronary implantation of a carbofilm-coated stent.
Topics: Aspirin; Carbon; Cause of Death; Clopidogrel; Coated Materials, Biocompatible; Coronary Disease; Coronary Restenosis; Coronary Thrombosis; Drug Combinations; Equipment Design; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Prospective Studies; Reoperation; Stents; Ticlopidine; Treatment Outcome | 2007 |
Patients with prior myocardial infarction, stroke, or symptomatic peripheral arterial disease in the CHARISMA trial.
Topics: Aged; Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Treatment Outcome | 2007 |
Influence of antiplatelet therapy on cerebral micro-emboli after carotid endarterectomy using postoperative transcranial Doppler monitoring.
Topics: Aged; Anticoagulants; Aspirin; Aspirin, Dipyridamole Drug Combination; Clopidogrel; Dextrans; Dipyridamole; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Endarterectomy, Carotid; Female; Hemorrhage; Humans; Intracranial Embolism; Ischemic Attack, Transient; Male; Middle Aged; Middle Cerebral Artery; Pilot Projects; Platelet Aggregation Inhibitors; Postoperative Care; Prospective Studies; Stroke; Ticlopidine; Treatment Outcome; Ultrasonography, Doppler, Transcranial | 2007 |
[Effectiveness of treatment and prophylactic methods in persons with ischemic heart disease risk factors].
Topics: Adult; Aspirin; Dipyridamole; Drug Therapy, Combination; Exercise; Feeding Behavior; Female; Humans; Life Style; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation Inhibitors; Prospective Studies; Risk Factors; Survival Rate; Ticlopidine | 2007 |
[Absence of benefit with triple antiaggregation in acute non persistent ST segment elevation myocardial infarction in patients not subjected to early interventionism].
Topics: Aged; Aspirin; Clopidogrel; Electrocardiography; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine; Tirofiban; Tyrosine | 2007 |
Long-term clinical benefit of sirolimus-eluting stent implantation in diabetic patients with de novo coronary stenoses: long-term results of the DIABETES trial.
Topics: Aged; Aspirin; Blood Vessel Prosthesis; Clopidogrel; Coronary Restenosis; Coronary Stenosis; Death, Sudden, Cardiac; Diabetic Angiopathies; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Male; Myocardial Infarction; Myocardial Revascularization; Platelet Aggregation Inhibitors; Prospective Studies; Prosthesis Failure; Reoperation; Sirolimus; Ticlopidine; Treatment Outcome | 2007 |
Effects of persistent platelet reactivity despite aspirin therapy on cardiac troponin I and creatine kinase-MB levels after elective percutaneous coronary interventions.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Biomarkers; Clopidogrel; Coronary Artery Disease; Creatine Kinase, MB Form; Drug Resistance; Female; Humans; Male; Middle Aged; Myocardium; Necrosis; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Tablets, Enteric-Coated; Thrombosis; Ticlopidine; Time Factors; Troponin I; Up-Regulation | 2008 |
The additive antiplatelet action of clopidogrel in patients with coronary artery disease treated with aspirin.
Topics: Adenosine Diphosphate; Adult; Aged; Aspirin; Biomarkers; Case-Control Studies; Clopidogrel; Coronary Artery Disease; Cross-Over Studies; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Flow Cytometry; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine; Treatment Outcome | 2007 |
Effects of preoperative aspirin and clopidogrel therapy on perioperative blood loss and blood transfusion requirements in patients undergoing off-pump coronary artery bypass graft surgery.
Topics: Aspirin; Blood Loss, Surgical; Blood Transfusion; Clopidogrel; Coronary Artery Bypass; Drug Administration Schedule; Drug Therapy, Combination; Female; Fibrinolytic Agents; Humans; Length of Stay; Male; Middle Aged; Platelet Aggregation Inhibitors; Premedication; Prospective Studies; Ticlopidine | 2007 |
Prolonged dual antiplatelet therapy after percutaneous coronary intervention reduces ischemic events without affecting the need for repeat revascularization: insights from the CREDO trial.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Contraindications; Coronary Restenosis; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Ischemia; Myocardial Revascularization; Platelet Aggregation Inhibitors; Postoperative Care; Ticlopidine; Time Factors; Treatment Outcome | 2007 |
Quality assessment of platelet rich plasma during anti-platelet therapy.
Topics: Aged; Aspirin; Clopidogrel; Female; Humans; Intercellular Signaling Peptides and Proteins; Male; Middle Aged; Pilot Projects; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Platelet Transfusion; Quality Assurance, Health Care; Surgical Procedures, Operative; Ticlopidine; Wound Healing | 2007 |
Oral anticoagulant and antiplatelet therapy and peripheral arterial disease.
Topics: Acenocoumarol; Administration, Oral; Anticoagulants; Aspirin; Atherosclerosis; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Female; Follow-Up Studies; Hemorrhage; Humans; Incidence; Male; Middle Aged; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Ticlopidine; Warfarin | 2007 |
Therapeutic benefit of low-dose clopidogrel in patients undergoing carotid surgery is linked to variability in the platelet adenosine diphosphate response and patients' weight.
Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Body Weight; Clopidogrel; Endarterectomy, Carotid; Humans; Placebos; Platelet Activation; Platelet Aggregation Inhibitors; Postoperative Complications; Statistics as Topic; Thrombosis; Ticlopidine | 2007 |
An analysis of mortality rates with dual-antiplatelet therapy in the primary prevention population of the CHARISMA trial.
Topics: Aged; Aspirin; Atherosclerosis; Cardiovascular Diseases; Clopidogrel; Disease-Free Survival; Drug Therapy, Combination; Epidemiologic Methods; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2007 |
Effects of triple antiplatelet therapy (aspirin, clopidogrel, and cilostazol) on platelet aggregation and P-selectin expression in patients undergoing coronary artery stent implantation.
Topics: Aspirin; Biomarkers; Blood Vessel Prosthesis Implantation; Cilostazol; Clopidogrel; Coronary Restenosis; Coronary Stenosis; Drug Therapy, Combination; Female; Flow Cytometry; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Revascularization; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Preoperative Care; Radiography; Stents; Tetrazoles; Ticlopidine; Treatment Outcome | 2007 |
Effects of recombinant human erythropoietin on antiplatelet action of aspirin and clopidogrel in healthy subjects: results of a double-blind, placebo-controlled randomized trial.
Topics: Adult; Aspirin; Blood Platelets; Clopidogrel; Double-Blind Method; Erythropoietin; Female; Humans; Male; Platelet Aggregation Inhibitors; Recombinant Proteins; Ticlopidine | 2007 |
Efficacy and safety of triple antiplatelet therapy with and without concomitant anticoagulation during elective percutaneous coronary intervention (the REMOVE trial).
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Eptifibatide; Female; Heparin; Humans; Male; Middle Aged; Peptides; Pilot Projects; Platelet Aggregation Inhibitors; Prospective Studies; Pyridines; Ticlopidine; Treatment Outcome | 2007 |
Comparison of triple versus dual antiplatelet therapy after drug-eluting stent implantation (from the DECLARE-Long trial).
Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; Drug Delivery Systems; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; Paclitaxel; Platelet Aggregation Inhibitors; Sirolimus; Stents; Tetrazoles; Ticlopidine; Time Factors; Treatment Outcome; Tunica Intima | 2007 |
Fast assessment of stroke and transient ischaemic attack to prevent early recurrence (FASTER): a randomised controlled pilot trial.
Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Clopidogrel; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Ischemic Attack, Transient; Male; Middle Aged; Pilot Projects; Platelet Aggregation Inhibitors; Risk Reduction Behavior; Secondary Prevention; Severity of Illness Index; Simvastatin; Stroke; Ticlopidine; Time Factors; Treatment Outcome | 2007 |
TAXUS VI 2-year follow-up: randomized comparison of polymer-based paclitaxel-eluting with bare metal stents for treatment of long, complex lesions.
Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Coronary Thrombosis; Drug-Eluting Stents; Epidemiologic Methods; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Myocardial Revascularization; Paclitaxel; Platelet Aggregation Inhibitors; Polymers; Ticlopidine | 2007 |
A novel fifteen minute test for assessment of individual time-dependent clotting responses to aspirin and clopidogrel using modified thrombelastography.
Topics: Adult; Aged; Aspirin; Blood Coagulation; Clopidogrel; Female; Humans; Male; Platelet Aggregation Inhibitors; Reproducibility of Results; Thrombelastography; Ticlopidine | 2007 |
To adjust or not to adjust the platelet count in light transmission aggregometry in patients receiving dual aspirin/clopidogrel treatment.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Platelet-Rich Plasma; Prospective Studies; Reproducibility of Results; Ticlopidine | 2007 |
[The changes and effects of antiplatelet agents on platelet-leukocyte aggregation in patients with acute cerebral infarction].
Topics: Aged; Aspirin; C-Reactive Protein; Cerebral Infarction; Clopidogrel; Female; Humans; Male; Middle Aged; P-Selectin; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2007 |
Effect of cilostazol on in-stent neointimal hyperplasia after coronary artery stenting: a quantative coronary angiography and volumetric intravascular ultrasound study.
Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Angiography; Coronary Disease; Coronary Vessels; Drug Therapy, Combination; Female; Humans; Hyperplasia; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Stents; Tetrazoles; Ticlopidine; Tunica Intima; Ultrasonography, Interventional | 2007 |
Safety, tolerability, and initial efficacy of AZD6140, the first reversible oral adenosine diphosphate receptor antagonist, compared with clopidogrel, in patients with non-ST-segment elevation acute coronary syndrome: primary results of the DISPERSE-2 tri
Topics: Acute Coronary Syndrome; Adenosine; Administration, Oral; Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Female; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Risk Factors; Ticagrelor; Ticlopidine | 2007 |
Prasugrel versus clopidogrel in patients with acute coronary syndromes.
Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Prodrugs; Purinergic P2 Receptor Antagonists; Stroke; Thiophenes; Thrombosis; Ticlopidine | 2007 |
Cost-effectiveness of clopidogrel in acute coronary syndromes in Canada: a long-term analysis based on the CURE trial.
Topics: Acute Coronary Syndrome; Aged; Angina, Unstable; Angioplasty, Balloon, Coronary; Aspirin; Canada; Clopidogrel; Cost of Illness; Cost-Benefit Analysis; Drug Therapy, Combination; Female; Hospitalization; Humans; Length of Stay; Life Expectancy; Male; Middle Aged; Outcome Assessment, Health Care; Platelet Aggregation Inhibitors; Quality-Adjusted Life Years; Ticlopidine; Time Factors | 2007 |
Prevalence and risk factors for aspirin and clopidogrel resistance in cerebrovascular stenting.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Vessel Prosthesis; Cerebrovascular Disorders; Clopidogrel; Cohort Studies; Comorbidity; Drug Resistance; Female; Graft Occlusion, Vascular; Humans; Illinois; Incidence; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Assessment; Risk Factors; Stents; Ticlopidine | 2008 |
Incidence of stroke in paroxysmal versus sustained atrial fibrillation in patients taking oral anticoagulation or combined antiplatelet therapy: an ACTIVE W Substudy.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Drug Therapy, Combination; Female; Humans; Incidence; Male; Middle Aged; Platelet Aggregation Inhibitors; Stroke; Thromboembolism; Ticlopidine; Treatment Outcome | 2007 |
Cilostazol could ameliorate platelet responsiveness to clopidogrel in patients undergoing primary percutaneous coronary intervention.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Biomarkers; Blood Platelets; CD40 Antigens; Cilostazol; Clopidogrel; Combined Modality Therapy; Drug Therapy, Combination; Electrocardiography; Female; Humans; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation Inhibitors; Tetrazoles; Ticlopidine; Treatment Outcome | 2007 |
Prasugrel achieves greater and faster P2Y12receptor-mediated platelet inhibition than clopidogrel due to more efficient generation of its active metabolite in aspirin-treated patients with coronary artery disease.
Topics: Adult; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Double-Blind Method; Female; Humans; Male; Middle Aged; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Ticlopidine; Treatment Outcome | 2008 |
Effect of clopidogrel treatment on stress-induced platelet activation and myocardial ischemia in aspirin-treated patients with stable coronary artery disease.
Topics: Adenosine Diphosphate; Aged; Aspirin; Blood Platelets; C-Reactive Protein; CD40 Ligand; Clopidogrel; Collagen; Coronary Artery Disease; Double-Blind Method; Drug Therapy, Combination; Electrocardiography, Ambulatory; Exercise Test; Flow Cytometry; Heart Rate; Humans; Interleukin-6; Leukocytes; Male; Middle Aged; Myocardial Ischemia; P-Selectin; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Research Design; Stress, Physiological; Thrombin; Ticlopidine; Treatment Outcome | 2007 |
The significance of vasodilator-stimulated phosphoprotein for risk stratification of stent thrombosis.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Aspirin; Cell Adhesion Molecules; Clopidogrel; Coronary Angiography; Drug Therapy, Combination; Female; Flow Cytometry; Humans; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prospective Studies; Reproducibility of Results; Research Design; Risk Assessment; Risk Factors; ROC Curve; Sensitivity and Specificity; Stents; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2007 |
[Effects of intensive antiplatelet therapy in patients with high platelet aggregability after percutaneous coronary intervention].
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Ticlopidine | 2007 |
Effects of clopidogrel and aspirin in combination versus aspirin alone on platelet activation and major receptor expression in diabetic patients: the PLavix Use for Treatment Of Diabetes (PLUTO-Diabetes) trial.
Topics: Adult; Analysis of Variance; Aspirin; Biomarkers; Blood Chemical Analysis; Clopidogrel; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Drug Therapy, Combination; Female; Flow Cytometry; Humans; Male; Middle Aged; Myocardial Ischemia; Pilot Projects; Platelet Activation; Platelet Aggregation; Platelet Function Tests; Probability; Prognosis; Receptor, PAR-2; Reference Values; Risk Assessment; Survival Rate; Ticlopidine; Treatment Outcome | 2008 |
Evaluation of proton pump inhibitor use in patients with acute coronary syndromes based on risk factors for gastrointestinal bleed.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Female; Fibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Proton Pump Inhibitors; Risk Factors; Ticlopidine; Treatment Outcome; Warfarin | 2007 |
Variable responsiveness to clopidogrel and aspirin among patients with acute coronary syndrome as assessed by platelet function tests.
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Aspirin; Clopidogrel; Female; Humans; Male; Middle Aged; Nephelometry and Turbidimetry; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet-Rich Plasma; ROC Curve; Sensitivity and Specificity; Ticlopidine | 2008 |
Randomized comparison of cilostazol vs clopidogrel after drug-eluting stenting in diabetic patients--clilostazol for diabetic patients in drug-eluting stent (CIDES) trial.
Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; Diabetes Complications; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Male; Middle Aged; Tetrazoles; Ticlopidine; Treatment Outcome | 2008 |
The effects of antiplatelet agents on platelet-leukocyte aggregations in patients with acute cerebral infarction.
Topics: Aged; Aspirin; Blood Platelets; Cell Adhesion; Cerebral Infarction; Clopidogrel; Female; Humans; Leukocytes; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Ticlopidine | 2009 |
Platelet and endothelial activity in comorbid major depression and coronary artery disease patients treated with citalopram: the Canadian Cardiac Randomized Evaluation of Antidepressant and Psychotherapy Efficacy Trial (CREATE) biomarker sub-study.
Topics: Adult; Aged; Antidepressive Agents; Aspirin; beta-Thromboglobulin; Biomarkers; Blood Platelets; Citalopram; Clopidogrel; Comorbidity; Coronary Disease; Depressive Disorder, Major; Drug Interactions; Endothelium, Vascular; Female; Humans; Intercellular Adhesion Molecule-1; Male; Middle Aged; Nitric Oxide; P-Selectin; Platelet Aggregation Inhibitors; Psychotherapy; Selective Serotonin Reuptake Inhibitors; Ticlopidine; Young Adult | 2009 |
Dosing of clopidogrel for platelet inhibition in infants and young children: primary results of the Platelet Inhibition in Children On cLOpidogrel (PICOLO) trial.
Topics: Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Hemorrhage; Humans; Infant; Infant, Newborn; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2008 |
Prevalence of platelet nonresponsiveness to aspirin in patients treated for secondary stroke prophylaxis and in patients with recurrent ischemic events.
Topics: Age Factors; Aged; Anti-Inflammatory Agents; Arachidonic Acid; Aspirin; Blood Platelets; Clopidogrel; Collagen; Coronary Artery Disease; Dipyridamole; Drug Therapy, Combination; Female; Humans; Ischemic Attack, Transient; Male; Odds Ratio; Platelet Aggregation; Recurrence; Stroke; Ticlopidine; Time Factors; Treatment Failure | 2008 |
Association of impaired thrombolysis in myocardial infarction myocardial perfusion grade with ventricular tachycardia and ventricular fibrillation following fibrinolytic therapy for ST-segment elevation myocardial infarction.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Circulation; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Female; Humans; Incidence; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Proportional Hazards Models; Retrospective Studies; Risk Factors; Tachycardia, Ventricular; Thrombolytic Therapy; Ticlopidine; Treatment Outcome; Ventricular Fibrillation | 2008 |
Platelet inhibition by low-dose aspirin but not by clopidogrel reduces the axon-reflex current-induced vasodilation in humans.
Topics: Acetylcholine; Adenosine Diphosphate; Adult; Aspirin; Axons; Blood Platelets; Clopidogrel; Electric Stimulation; Endothelium, Vascular; Female; Humans; Iontophoresis; Laser-Doppler Flowmetry; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Signal Transduction; Ticlopidine; Vasodilation; Vasodilator Agents | 2008 |
[Unstable angina: efficacy and tolerability of therapy with aspirin and aspirin combined with ticlopidine].
Topics: Angina, Unstable; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Disease Progression; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine | 2007 |
Sirolimus-eluting stents versus bare-metal stents in patients with ST-segment elevation myocardial infarction: 9-month angiographic and intravascular ultrasound results and 12-month clinical outcome results from the MISSION! Intervention Study.
Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Aspirin; Clopidogrel; Drug-Eluting Stents; Female; Heparin; Humans; Immunoglobulin Fab Fragments; Immunosuppressive Agents; Male; Middle Aged; Myocardial Infarction; Myocardial Revascularization; Proportional Hazards Models; Sirolimus; Stents; Ticlopidine; Time Factors; Treatment Outcome; Ultrasonography, Interventional | 2008 |
The use of the VerifyNow P2Y12 point-of-care device to monitor platelet function across a range of P2Y12 inhibition levels following prasugrel and clopidogrel administration.
Topics: Adult; Aspirin; Blood Coagulation Tests; Blood Platelets; Clopidogrel; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Monitoring; Female; Humans; Male; Middle Aged; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Point-of-Care Systems; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Reference Values; Reproducibility of Results; Thiophenes; Ticlopidine | 2008 |
Clopidogrel and aspirin versus aspirin alone for the prevention of stroke in patients with a history of atrial fibrillation: subgroup analysis of the CHARISMA randomized trial.
Topics: Aged; Aspirin; Atrial Fibrillation; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Female; Humans; Male; Platelet Aggregation Inhibitors; Risk Factors; Stroke; Ticlopidine; Treatment Outcome | 2008 |
Risks and benefits of oral anticoagulation compared with clopidogrel plus aspirin in patients with atrial fibrillation according to stroke risk: the atrial fibrillation clopidogrel trial with irbesartan for prevention of vascular events (ACTIVE-W).
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Anticoagulants; Aspirin; Atrial Fibrillation; Biphenyl Compounds; Cerebral Hemorrhage; Clinical Protocols; Clopidogrel; Drug Combinations; Drug Therapy, Combination; Female; Humans; Irbesartan; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Assessment; Risk Factors; Stroke; Tetrazoles; Ticlopidine; Treatment Outcome; Warfarin | 2008 |
Antiplatelet profiles of the fixed-dose combination of extended-release dipyridamole and low-dose aspirin compared with clopidogrel with or without aspirin in patients with type 2 diabetes and a history of transient ischemic attack: a randomized, single-b
Topics: Adult; Aged; Aspirin; Aspirin, Dipyridamole Drug Combination; Biomarkers; Clopidogrel; Diabetes Mellitus, Type 2; Dipyridamole; Drug Combinations; Drug Therapy, Combination; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Pilot Projects; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Single-Blind Method; Ticlopidine; Time Factors; Treatment Outcome | 2008 |
Platelet aggregation and recruitment with aspirin-clopidogrel therapy.
Topics: Aspirin; Brain Ischemia; Clopidogrel; Cohort Studies; Drug Therapy, Combination; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Stroke; Thromboxane B2; Ticlopidine | 2008 |
Drug-eluting stenting followed by cilostazol treatment reduces late restenosis in patients with diabetes mellitus the DECLARE-DIABETES Trial (A Randomized Comparison of Triple Antiplatelet Therapy with Dual Antiplatelet Therapy After Drug-Eluting Stent Im
Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; Coronary Vessels; Diabetes Mellitus; Diabetic Angiopathies; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Hyperplasia; Male; Middle Aged; Platelet Aggregation Inhibitors; Tetrazoles; Ticlopidine; Treatment Outcome; Tunica Intima | 2008 |
[Effect of the acetylosalicyd acid (ASA) and ticlopidine therapy on clinical condition and parameters of blood platelets in patients with peripheral arterial occlusive disease (PAOD)].
Topics: Adult; Aged; Arteriosclerosis Obliterans; Aspirin; Blood Platelets; Exercise Test; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2007 |
Effect of tirofiban plus clopidogrel and aspirin on primary percutaneous coronary intervention via transradial approach in patients with acute myocardial infarction.
Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine; Tirofiban; Tyrosine; Vasodilation | 2008 |
The importance of anticoagulant agents in measuring platelet aggregation in patients treated with clopidogrel and aspirin.
Topics: Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Blood Platelets; Citrates; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Glycoprotein GPIIb-IIIa Complex; Sodium Citrate; Ticlopidine | 2008 |
[Removing phlegm and dispelling stasis method combined with Western medicine for treatment of cerebrovascular stenosis].
Topics: Adult; Aged; Aspirin; C-Reactive Protein; Carotid Stenosis; Cerebrovascular Disorders; Clopidogrel; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Fibrinogen; Humans; Male; Middle Aged; Phytotherapy; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2008 |
Pharmacokinetics of clopidogrel in patients with stent thrombosis.
Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Female; Humans; Male; Middle Aged; Pharmacokinetics; Platelet Aggregation; Platelet Function Tests; Stents; Thrombosis; Ticlopidine | 2008 |
Early and late benefits of prasugrel in patients with acute coronary syndromes undergoing percutaneous coronary intervention: a TRITON-TIMI 38 (TRial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet InhibitioN with Prasugrel-Thrombolys
Topics: Acute Coronary Syndrome; Angina, Unstable; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Combined Modality Therapy; Drug Therapy, Combination; Hemorrhage; Humans; Kaplan-Meier Estimate; Myocardial Infarction; Myocardial Ischemia; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Proportional Hazards Models; Purinergic P2 Receptor Antagonists; Stents; Thiophenes; Ticlopidine | 2008 |
Phase 1b randomized study of antidote-controlled modulation of factor IXa activity in patients with stable coronary artery disease.
Topics: Aged; Antidotes; Aptamers, Nucleotide; Aspirin; Clopidogrel; Coronary Artery Disease; Double-Blind Method; Drug Combinations; Factor IXa; Female; Humans; Male; Middle Aged; Oligonucleotides; Ticlopidine; Treatment Outcome | 2008 |
Tailoring treatment with tirofiban in patients showing resistance to aspirin and/or resistance to clopidogrel (3T/2R). Rationale for the study and protocol design.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Biomarkers; Clopidogrel; Double-Blind Method; Drug Resistance; Europe; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prospective Studies; Research Design; Ticlopidine; Tirofiban; Treatment Outcome; Troponin I; Troponin T; Tyrosine | 2008 |
A randomized study assessing the impact of cilostazol on platelet function profiles in patients with diabetes mellitus and coronary artery disease on dual antiplatelet therapy: results of the OPTIMUS-2 study.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cilostazol; Clopidogrel; Coronary Artery Disease; Cross-Over Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Double-Blind Method; Female; Humans; Male; Middle Aged; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Tetrazoles; Ticlopidine; Treatment Outcome | 2008 |
Switching directly to prasugrel from clopidogrel results in greater inhibition of platelet aggregation in aspirin-treated subjects.
Topics: Adenosine Diphosphate; Adult; Aspirin; Clopidogrel; Drug-Related Side Effects and Adverse Reactions; Female; Hemorrhage; Humans; Male; Middle Aged; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Thiophenes; Ticlopidine | 2008 |
Effect of clopidogrel on adhesion molecules, hemostasis, and fibrinolysis in coronary heart disease.
Topics: Aged; Angina Pectoris; Aspirin; Cell Adhesion Molecules; Chronic Disease; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Fibrinolysis; Flow Cytometry; Hemostasis; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine | 2008 |
The role of clopidogrel and acetylsalicylic acid in the prevention of early-phase graft occlusion due to reactive thrombocytosis after coronary artery bypass operation.
Topics: Aspirin; Clopidogrel; Coronary Artery Bypass; Female; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Thrombocytosis; Ticlopidine; Treatment Outcome | 2008 |
Long-term cost-effectiveness of clopidogrel in STEMI patients.
Topics: Aged; Aspirin; Clopidogrel; Cost-Benefit Analysis; Decision Trees; Double-Blind Method; Female; Humans; Male; Middle Aged; Myocardial Infarction; Ticlopidine; Time Factors; Treatment Outcome | 2009 |
Aspirin and clopidogrel treatment impair nitric oxide biosynthesis by platelets.
Topics: Adrenergic beta-Antagonists; Adult; Aspirin; Blood Platelets; Clopidogrel; Coronary Disease; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle Aged; Nitric Oxide; Platelet Aggregation Inhibitors; Receptors, Adrenergic, beta; Signal Transduction; Ticlopidine | 2008 |
The antiplatelet effect of atorvastatin in patients with acute coronary syndrome depends on the hs-CRP level.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Atorvastatin; C-Reactive Protein; Clopidogrel; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrroles; Ticlopidine | 2008 |
Aspirin and clopidogrel with or without phenprocoumon after drug eluting coronary stent placement in patients on chronic oral anticoagulation.
Topics: Aged; Anticoagulants; Aspirin; Clopidogrel; Coronary Vessels; Drug Therapy, Combination; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Male; Phenprocoumon; Platelet Aggregation Inhibitors; Postoperative Period; Prospective Studies; Stroke; Ticlopidine; Treatment Outcome | 2008 |
Comparison of increased aspirin dose versus combined aspirin plus clopidogrel therapy in patients with diabetes mellitus and coronary heart disease and impaired antiplatelet response to low-dose aspirin.
Topics: Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Failure | 2008 |
A randomised controlled trial of triple antiplatelet therapy (aspirin, clopidogrel and dipyridamole) in the secondary prevention of stroke: safety, tolerability and feasibility.
Topics: Aged; Aspirin; Blood Pressure; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Drug Tolerance; Feasibility Studies; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Patient Selection; Platelet Aggregation Inhibitors; Pulse; Safety; Single-Blind Method; Stroke; Ticlopidine | 2008 |
Clinical evaluation of a novel occluder device (Occlutech) for percutaneous transcatheter closure of patent foramen ovale (PFO).
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alloys; Aspirin; Balloon Occlusion; Cardiac Catheterization; Clopidogrel; Echocardiography, Transesophageal; Female; Femoral Vein; Fluoroscopy; Follow-Up Studies; Foramen Ovale, Patent; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Prostheses and Implants; Ticlopidine; Young Adult | 2008 |
Effect of PCI on quality of life in patients with stable coronary disease.
Topics: Adrenergic beta-Antagonists; Amlodipine; Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; Calcium Channel Blockers; Clopidogrel; Combined Modality Therapy; Coronary Disease; Cross-Over Studies; Drug Therapy, Combination; Female; Health Status; Humans; Isosorbide Dinitrate; Male; Metoprolol; Middle Aged; Patient Satisfaction; Platelet Aggregation Inhibitors; Quality of Life; Stents; Surveys and Questionnaires; Ticlopidine; Vasodilator Agents | 2008 |
Antiplatelet therapy vs. anticoagulation in cervical artery dissection: rationale and design of the Cervical Artery Dissection in Stroke Study (CADISS).
Topics: Anticoagulants; Aortic Dissection; Aspirin; Clinical Protocols; Clopidogrel; Diagnostic Imaging; Dipyridamole; Drug Therapy, Combination; Endpoint Determination; Feasibility Studies; Heparin; Humans; Patient Selection; Platelet Aggregation Inhibitors; Prospective Studies; Quality Assurance, Health Care; Research Design; Sample Size; Single-Blind Method; Stroke; Ticlopidine; United Kingdom; Warfarin | 2007 |
Incidence and clinical impact of dual nonresponsiveness to aspirin and clopidogrel in patients with drug-eluting stents.
Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Cohort Studies; Coronary Artery Disease; Drug Resistance, Multiple; Drug-Eluting Stents; Female; Graft Occlusion, Vascular; Humans; Incidence; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Radiography; Risk Factors; Ticlopidine | 2008 |
Role of reticulated platelets and platelet size heterogeneity on platelet activity after dual antiplatelet therapy with aspirin and clopidogrel in patients with stable coronary artery disease.
Topics: Aged; Aspirin; Cell Size; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Flow Cytometry; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Count; Ticlopidine | 2008 |
Thienopyridine resistance among patients undergoing intracoronary stent implantation and treated with dual antiplatelet therapy: assessment of some modifying factors.
Topics: Adult; Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Vessels; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Stents; Ticlopidine; Time Factors | 2008 |
Aspirin and extended-release dipyridamole versus clopidogrel for recurrent stroke.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Benzimidazoles; Benzoates; Brain Ischemia; Clopidogrel; Delayed-Action Preparations; Dipyridamole; Double-Blind Method; Drug Therapy, Combination; Factor Analysis, Statistical; Female; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Proportional Hazards Models; Risk; Secondary Prevention; Stroke; Telmisartan; Ticlopidine; Vascular Diseases | 2008 |
[A clinical trial of using antiplatelet therapy to prevent restenosis following peripheral artery angioplasty and stenting].
Topics: Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Arteriosclerosis Obliterans; Aspirin; Catheterization, Peripheral; Clopidogrel; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Care; Postoperative Period; Stents; Ticlopidine; Treatment Outcome | 2008 |
Effects of aspirin plus extended-release dipyridamole versus clopidogrel and telmisartan on disability and cognitive function after recurrent stroke in patients with ischaemic stroke in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFE
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Aspirin; Benzimidazoles; Benzoates; Clopidogrel; Cognition; Dipyridamole; Disability Evaluation; Double-Blind Method; Drug Administration Schedule; Drug Delivery Systems; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; International Cooperation; Male; Mental Status Schedule; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Secondary Prevention; Severity of Illness Index; Stroke; Telmisartan; Ticlopidine | 2008 |
Effects of aspirin and clopidogrel in healthy men measured by platelet aggregation and PFA-100.
Topics: Adenosine Diphosphate; Adolescent; Adult; Arachidonic Acid; Aspirin; Clopidogrel; Collagen; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Resistance; Epinephrine; Humans; Male; Middle Aged; Nephelometry and Turbidimetry; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Reference Values; Ticlopidine | 2008 |
Effects of aspirin dose on ischaemic events and bleeding after percutaneous coronary intervention: insights from the PCI-CURE study.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Death, Sudden, Cardiac; Double-Blind Method; Female; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Treatment Outcome | 2009 |
Comparison of four tests to assess inhibition of platelet function by clopidogrel in stable coronary artery disease patients.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Double-Blind Method; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2008 |
Safety and tolerability of 600 mg clopidogrel bolus in patients with acute ischemic stroke: preliminary experience.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Brain Ischemia; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Recurrence; Stroke; Ticlopidine | 2008 |
ADP-induced platelet aggregation frequently fails to detect impaired clopidogrel-responsiveness in patients with coronary artery disease compared to a P2Y12-specific assay.
Topics: Adenosine Diphosphate; Aged; Aspirin; Blood Platelets; Clopidogrel; Comorbidity; Coronary Artery Disease; Drug Resistance; Female; Flow Cytometry; Humans; Incidence; Male; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Signal Transduction; Ticlopidine | 2008 |
Greater reduction of platelet activation markers and platelet-monocyte aggregates by prasugrel compared to clopidogrel in stable coronary artery disease.
Topics: Adult; Aspirin; Biomarkers; Blood Platelets; Cell Communication; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Monocytes; P-Selectin; Piperazines; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prasugrel Hydrochloride; Thiophenes; Ticlopidine | 2008 |
Tirofiban optimizes platelet inhibition for immediate percutaneous coronary intervention in high-risk acute coronary syndromes.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Infarction; Necrosis; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine; Tirofiban; Treatment Outcome; Tyrosine | 2008 |
[Influence of antiplatelet drugs (AD) on the efectiveness of combined therapy in patients with small cell lung cancer. Part I. Influence of AD on the haemostatic system].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Blood Coagulation; Carcinoma, Small Cell; Cyclophosphamide; Dactinomycin; Humans; Lung Neoplasms; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Polydeoxyribonucleotides; Radiotherapy, Adjuvant; Survival Rate; Ticlopidine; Vincristine | 2008 |
Benefit of oral anticoagulant over antiplatelet therapy in atrial fibrillation depends on the quality of international normalized ratio control achieved by centers and countries as measured by time in therapeutic range.
Topics: Administration, Oral; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Brazil; Clopidogrel; Drug Therapy, Combination; Europe; Humans; International Normalized Ratio; Middle Aged; North America; Platelet Aggregation Inhibitors; Quality Control; South Africa; Ticlopidine; Time Factors; Treatment Outcome | 2008 |
Effect of increased aspirin dose after stenting in association with ClOpidogrel: the FIASCO randomized study.
Topics: Adenosine Diphosphate; Aged; Angina Pectoris; Arachidonic Acid; Aspirin; Blood Platelets; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Prospective Studies; Ticlopidine; Time Factors; Treatment Outcome | 2009 |
Comparison of laboratory detection methods of aspirin resistance in coronary artery disease patients.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Clinical Laboratory Techniques; Clopidogrel; Coronary Artery Disease; Drug Resistance; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2010 |
Comparison of collagen versus adenosine diphosphate in detecting antiplatelet effect in patients with coronary artery disease.
Topics: Adenosine Diphosphate; Aged; Aspirin; Clopidogrel; Collagen; Coronary Artery Disease; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prospective Studies; Ticlopidine; Treatment Outcome | 2009 |
Population pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel in aspirin-treated patients with stable coronary artery disease.
Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Models, Biological; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Ticlopidine | 2008 |
Design and rationale of CURRENT-OASIS 7: a randomized, 2 x 2 factorial trial evaluating optimal dosing strategies for clopidogrel and aspirin in patients with ST and non-ST-elevation acute coronary syndromes managed with an early invasive strategy.
Topics: Acute Coronary Syndrome; Adult; Aged; Angioplasty, Balloon, Coronary; Aspirin; Cause of Death; Clopidogrel; Combined Modality Therapy; Coronary Angiography; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Electrocardiography; Female; Follow-Up Studies; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Recurrence; Stroke; Ticlopidine; Treatment Outcome | 2008 |
The ELAPSE (Evaluation of Long-Term Clopidogrel Antiplatelet and Systemic Anti-Inflammatory Effects) study.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Humans; Inflammation; Male; Middle Aged; Pilot Projects; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Stents; Ticlopidine | 2008 |
Randomized trial comparing 600- with 300-mg loading dose of clopidogrel in patients with non-ST elevation acute coronary syndrome undergoing percutaneous coronary intervention: results of the Platelet Responsiveness to Aspirin and Clopidogrel and Troponin
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Clopidogrel; Female; Humans; Male; Middle Aged; Myocardium; Necrosis; Platelet Aggregation Inhibitors; Ticlopidine; Troponin | 2009 |
Immediate versus deferred coronary angioplasty in non-ST-segment elevation acute coronary syndromes.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Female; Humans; Incidence; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine; Time Factors; Treatment Outcome | 2009 |
Thrombotic events in high risk patients are predicted by evaluating different pathways of platelet function.
Topics: Adenosine Diphosphate; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Arachidonic Acid; Aspirin; Clopidogrel; Collagen; Drug Resistance; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Likelihood Functions; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Predictive Value of Tests; Prospective Studies; Reproducibility of Results; Risk Assessment; Risk Factors; ROC Curve; Thrombosis; Ticlopidine | 2008 |
Patients with peripheral arterial disease in the CHARISMA trial.
Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Epidemiologic Methods; Female; Humans; Male; Middle Aged; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Ticlopidine | 2009 |
A randomized, placebo-controlled study of the effects of naproxen, aspirin, celecoxib or clopidogrel on gastroduodenal mucosal healing.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Clopidogrel; Drug Administration Schedule; Female; Gastric Mucosa; Humans; Male; Middle Aged; Naproxen; Peptic Ulcer; Pilot Projects; Pyrazoles; Sulfonamides; Ticlopidine; Young Adult | 2009 |
Bleeding risk associated with 1 year of dual antiplatelet therapy after percutaneous coronary intervention: Insights from the Clopidogrel for the Reduction of Events During Observation (CREDO) trial.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Incidence; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors | 2009 |
Comparison of methods to evaluate clopidogrel-mediated platelet inhibition after percutaneous intervention with stent implantation.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Cell Adhesion Molecules; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Reproducibility of Results; Sensitivity and Specificity; Stents; Ticlopidine | 2009 |
Iron-induced platelet aggregation measurement: a novel method to measure platelet function in stenting for ST segment elevation myocardial infarction.
Topics: Aged; Aspirin; Clopidogrel; Feasibility Studies; Female; Humans; Iron; Male; Middle Aged; Myocardial Infarction; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Reproducibility of Results; Stainless Steel; Stents; Ticlopidine; Tirofiban; Treatment Outcome; Tyrosine | 2009 |
The influence of body mass index on mortality and bleeding among patients with or at high-risk of atherothrombotic disease.
Topics: Aged; Aspirin; Body Mass Index; Clopidogrel; Coronary Disease; Female; Fibrinolytic Agents; Hemorrhage; Humans; Male; Platelet Aggregation Inhibitors; Prospective Studies; Risk Factors; Thrombosis; Ticlopidine | 2009 |
Factors influencing clopidogrel efficacy in patients with stable coronary artery disease undergoing elective percutaneous coronary intervention: statin's advantage and the smoking "paradox".
Topics: Age Factors; Aged; Angioplasty, Balloon, Coronary; Aspirin; Body Mass Index; Cell Adhesion Molecules; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Heparin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Male; Microfilament Proteins; Phosphoproteins; Platelet Aggregation Inhibitors; Renal Insufficiency; Sex Factors; Smoking; Ticlopidine; Treatment Outcome | 2009 |
Assessment of P2Y(12) inhibition with the point-of-care device VerifyNow P2Y12 in patients treated with prasugrel or clopidogrel coadministered with aspirin.
Topics: Anticoagulants; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Double-Blind Method; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Male; Optical Rotation; Phosphorylation; Piperazines; Point-of-Care Systems; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Thiophenes; Ticlopidine | 2009 |
Prasugrel compared with clopidogrel in patients undergoing percutaneous coronary intervention for ST-elevation myocardial infarction (TRITON-TIMI 38): double-blind, randomised controlled trial.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Bypass; Double-Blind Method; Endpoint Determination; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Ticlopidine | 2009 |
Randomized trial of warfarin, aspirin, and clopidogrel in patients with chronic heart failure: the Warfarin and Antiplatelet Therapy in Chronic Heart Failure (WATCH) trial.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Chronic Disease; Clopidogrel; Death; Double-Blind Method; Female; Fibrinolytic Agents; Heart Failure; Humans; Male; Middle Aged; Myocardial Infarction; Stroke; Stroke Volume; Ticlopidine; Warfarin | 2009 |
Heparin infusion after successful percutaneous coronary intervention: a prospective, randomized trial.
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coronary Angiography; Female; Hemorrhage; Heparin; Humans; Incidence; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation Inhibitors; Prospective Studies; Risk Factors; Ticlopidine; Time Factors | 2009 |
Comparison of ticagrelor, the first reversible oral P2Y(12) receptor antagonist, with clopidogrel in patients with acute coronary syndromes: Rationale, design, and baseline characteristics of the PLATelet inhibition and patient Outcomes (PLATO) trial.
Topics: Acute Coronary Syndrome; Adenosine; Administration, Oral; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Electrocardiography, Ambulatory; Female; Follow-Up Studies; Humans; Male; Middle Aged; Patient Satisfaction; Platelet Activation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Retrospective Studies; Surveys and Questionnaires; Ticagrelor; Ticlopidine; Treatment Outcome | 2009 |
Cilostazol in addition to aspirin and clopidogrel improves long-term outcomes after percutaneous coronary intervention in patients with acute coronary syndromes: a randomized, controlled study.
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Clopidogrel; Drug Therapy, Combination; Electrocardiography; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Radiography; Tetrazoles; Ticlopidine; Time Factors; Treatment Outcome; Young Adult | 2009 |
Effect of clopidogrel added to aspirin in patients with atrial fibrillation.
Topics: Aged; Aspirin; Atrial Fibrillation; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Embolism; Female; Follow-Up Studies; Hemorrhage; Humans; Incidence; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk; Stroke; Ticlopidine; Vascular Diseases; Vitamin K | 2009 |
Efficacy of clopidrogel on reperfusion and high-sensitivity C-reactive protein in patients with acute myocardial infarction.
Topics: Aspirin; C-Reactive Protein; Clopidogrel; Coronary Circulation; Creatine Kinase, MB Form; Drug Therapy, Combination; Electrocardiography; Female; Fibrinolytic Agents; Heparin; Humans; Inflammation; Male; Middle Aged; Myocardial Infarction; Myocardial Reperfusion; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors; Tissue Plasminogen Activator; Treatment Outcome | 2009 |
Clinical outcomes of patients with diabetic nephropathy randomized to clopidogrel plus aspirin versus aspirin alone (a post hoc analysis of the clopidogrel for high atherothrombotic risk and ischemic stabilization, management, and avoidance [CHARISMA] tri
Topics: Aspirin; Cardiovascular Diseases; Chi-Square Distribution; Clopidogrel; Diabetic Nephropathies; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Proportional Hazards Models; Survival Analysis; Ticlopidine; Treatment Outcome | 2009 |
Genetic variation of CYP2C19 affects both pharmacokinetic and pharmacodynamic responses to clopidogrel but not prasugrel in aspirin-treated patients with coronary artery disease.
Topics: Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Coronary Disease; Cytochrome P-450 CYP2C19; Drug Interactions; Female; Genetic Variation; Humans; Male; Middle Aged; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Ticlopidine | 2009 |
[Clopidogrel in the treatment of atrial fibrillation: benefit from addition to aspirin. The results of ACTIVE A trial].
Topics: Age Factors; Aged; Aspirin; Atrial Fibrillation; Clopidogrel; Drug Therapy, Combination; Follow-Up Studies; Humans; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Russia; Stroke; Survival Rate; Ticlopidine; Treatment Outcome | 2009 |
Clopidogrel 150 mg/day to overcome low responsiveness in patients undergoing elective percutaneous coronary intervention: results from the VASP-02 (Vasodilator-Stimulated Phosphoprotein-02) randomized study.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Europe; Female; Hemorrhage; Humans; Male; Microfilament Proteins; Middle Aged; Odds Ratio; Phosphoproteins; Phosphorylation; Platelet Aggregation Inhibitors; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Risk Assessment; Stents; Ticlopidine; Time Factors | 2008 |
Glycoprotein IIb/IIIa inhibitors improve outcome after coronary stenting in clopidogrel nonresponders: a prospective, randomized study.
Topics: Abciximab; Aged; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Disease-Free Survival; Drug Resistance; Drug Therapy, Combination; Female; Hemorrhage; Humans; Immunoglobulin Fab Fragments; Kaplan-Meier Estimate; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prospective Studies; Risk Assessment; Stents; Ticlopidine; Time Factors; Treatment Outcome | 2008 |
The effects of aspirin and clopidogrel response on myonecrosis after percutaneous coronary intervention: a BRIEF-PCI (Brief Infusion of Intravenous Eptifibatide Following Successful Percutaneous Coronary Intervention) trial substudy.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Eptifibatide; Female; Heart Diseases; Hemorrhage; Humans; Infusions, Intravenous; Male; Middle Aged; Myocardial Infarction; Necrosis; Peptides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prospective Studies; Ticlopidine; Time Factors; Treatment Outcome | 2008 |
Safety and efficacy of biodegradable polymer-coated sirolimus-eluting stents in "real-world" practice: 18-month clinical and 9-month angiographic outcomes.
Topics: Aged; Angioplasty, Balloon, Coronary; Asia; Aspirin; Cardiovascular Agents; Clopidogrel; Coated Materials, Biocompatible; Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Platelet Aggregation Inhibitors; Polymers; Product Surveillance, Postmarketing; Prospective Studies; Prosthesis Design; Registries; Risk Assessment; Sirolimus; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2009 |
Apixaban, an oral, direct, selective factor Xa inhibitor, in combination with antiplatelet therapy after acute coronary syndrome: results of the Apixaban for Prevention of Acute Ischemic and Safety Events (APPRAISE) trial.
Topics: Acute Coronary Syndrome; Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Factor Xa Inhibitors; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation Inhibitors; Pyrazoles; Pyridones; Ticlopidine; Young Adult | 2009 |
Static platelet adhesion, flow cytometry and serum TXB2 levels for monitoring platelet inhibiting treatment with ASA and clopidogrel in coronary artery disease: a randomised cross-over study.
Topics: Aged; Aspirin; Case-Control Studies; Clopidogrel; Coronary Disease; Cross-Over Studies; Female; Fibrinogen; Flow Cytometry; Health; Humans; Male; Middle Aged; P-Selectin; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Principal Component Analysis; Regression Analysis; Thromboxane B2; Ticlopidine | 2009 |
Intensifying platelet inhibition with tirofiban in poor responders to aspirin, clopidogrel, or both agents undergoing elective coronary intervention: results from the double-blind, prospective, randomized Tailoring Treatment with Tirofiban in Patients Sho
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Clopidogrel; Combined Modality Therapy; Coronary Artery Disease; Coronary Thrombosis; Double-Blind Method; Drug Resistance; Female; Humans; Incidence; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Prospective Studies; Risk Factors; Ticlopidine; Tirofiban; Tyrosine | 2009 |
[Difficulties in evaluating the efficacy of antiplatelet therapy in clinical practice].
Topics: Adult; Aspirin; Chronic Disease; Clopidogrel; Data Interpretation, Statistical; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2009 |
Clopidogrel and aspirin versus clopidogrel alone on graft patency after coronary artery bypass grafting.
Topics: Aged; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Coronary Stenosis; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Elective Surgical Procedures; Female; Graft Occlusion, Vascular; Graft Rejection; Graft Survival; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Probability; Prognosis; Survival Rate; Ticlopidine; Treatment Outcome; Vascular Patency | 2009 |
Thrombin formation and platelet activation at the site of vascular injury in patients with coronary artery disease treated with clopidogrel combined with aspirin.
Topics: Aspirin; Biomarkers; CD40 Ligand; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Drug Therapy, Combination; Humans; Lacerations; Male; Middle Aged; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Punctures; Skin; Thrombin; Ticlopidine; Veins | 2009 |
Cross validation of the Multiple Electrode Aggregometry. A prospective trial in healthy volunteers.
Topics: Adenosine Diphosphate; Adult; Alprostadil; Arachidonic Acid; Aspirin; Clopidogrel; Electrodes; Female; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Ticlopidine; Time Factors; Young Adult | 2009 |
Marked reduction of early stent thrombosis with pre-hospital initiation of high-dose Tirofiban in ST-segment elevation myocardial infarction.
Topics: Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coronary Thrombosis; Disease-Free Survival; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Electrocardiography; Emergency Medical Services; Female; Fibrinolytic Agents; Hemorrhage; Heparin; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Recurrence; Stents; Thrombolytic Therapy; Ticlopidine; Tirofiban; Tyrosine | 2009 |
Effect of prasugrel versus clopidogrel on outcomes among patients with acute coronary syndrome undergoing percutaneous coronary intervention without stent implantation: a TRial to assess Improvement in Therapeutic Outcomes by optimizing platelet inhibitio
Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Female; Humans; Male; Middle Aged; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Ticlopidine | 2009 |
Clopidogrel provides significantly greater inhibition of platelet activity than aspirin when combined with atorvastatin after coronary artery bypass grafting: a prospective randomized study.
Topics: Adenosine Diphosphate; Aged; Aspirin; Atorvastatin; Clopidogrel; Comorbidity; Coronary Artery Bypass; Coronary Disease; Drug Therapy, Combination; Female; Fibrinogen; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Lipoproteins, LDL; Male; Middle Aged; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Postoperative Complications; Prospective Studies; Pyrroles; Ticlopidine | 2010 |
A comparison of anticoagulation with bivalirudin and provisional GPIIb/IIIa inhibition with unfractionated heparin and mandatory GPIIb/IIIa inhibition during percutaneous coronary intervention in relation to platelet activation and the inhibition of coagu
Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Biomarkers; Blood Coagulation; CD40 Ligand; Clopidogrel; Drug Therapy, Combination; Female; Fibrinogen; Heparin; Hirudins; Humans; Lipoproteins; Male; Membrane Glycoproteins; Middle Aged; Monocytes; Peptide Fragments; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prothrombin; Recombinant Proteins; Thromboplastin; Thrombosis; Ticlopidine; Treatment Outcome | 2009 |
Effect of the thromboxane prostaglandin receptor antagonist terutroban on arterial thrombogenesis after repeated administration in patients treated for the prevention of ischemic stroke.
Topics: Aged; Aged, 80 and over; Aspirin; Biomarkers; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Intracranial Thrombosis; Male; Middle Aged; Naphthalenes; Platelet Aggregation; Platelet Aggregation Inhibitors; Propionates; Receptors, Thromboxane; Stroke; Ticlopidine | 2009 |
Long term efficacy of abciximab bolus-only compared to abciximab bolus and infusion after transradial coronary stenting.
Topics: Abciximab; Aged; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Hemorrhage; Humans; Immunoglobulin Fab Fragments; Infusions, Parenteral; Injections; Length of Stay; Logistic Models; Male; Middle Aged; Myocardial Infarction; Patient Discharge; Platelet Aggregation Inhibitors; Proportional Hazards Models; Radial Artery; Risk Assessment; Risk Factors; Stents; Ticlopidine; Time Factors; Treatment Outcome | 2009 |
Randomized controlled trial of aspirin and clopidogrel versus aspirin and placebo on markers of smooth muscle proliferation before and after peripheral angioplasty.
Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon; Aspirin; Biomarkers; Blotting, Western; Cell Proliferation; Cells, Cultured; Clopidogrel; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; E-Selectin; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Graft Occlusion, Vascular; Humans; Intercellular Adhesion Molecule-1; Male; Middle Aged; Mitogen-Activated Protein Kinase 3; Multivariate Analysis; Muscle, Smooth, Vascular; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Platelet-Derived Growth Factor; Probability; Radiography; Reference Values; Statistics, Nonparametric; Ticlopidine | 2009 |
The effect of elinogrel on high platelet reactivity during dual antiplatelet therapy and the relation to CYP2C19*2 genotype: first experience in patients.
Topics: Adenosine Diphosphate; Administration, Oral; Aged; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Aspirin; Blood Coagulation; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Collagen; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Drug Therapy, Combination; Female; Gene Frequency; Genotype; Humans; Male; Microfilament Proteins; Middle Aged; Phenotype; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Purinergic P2 Receptor Antagonists; Quinazolinones; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Stents; Sulfonamides; Thrombelastography; Ticlopidine | 2010 |
Impact of final activated clotting time after transradial coronary stenting with maximal antiplatelet therapy.
Topics: Abciximab; Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Aspirin; Clopidogrel; Coronary Artery Disease; Creatine Kinase, MB Form; Female; Follow-Up Studies; Hematoma; Hemorrhage; Heparin; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Count; Premedication; Retreatment; Sex Factors; Stents; Ticlopidine; Troponin T; Whole Blood Coagulation Time | 2009 |
Design and rationale of the WOEST trial: What is the Optimal antiplatElet and anticoagulant therapy in patients with oral anticoagulation and coronary StenTing (WOEST).
Topics: Administration, Oral; Anticoagulants; Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Treatment Outcome | 2009 |
Comparison of the efficacy and safety of zotarolimus-, sirolimus-, and paclitaxel-eluting stents in patients with ST-elevation myocardial infarction.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Agents; Clopidogrel; Coronary Angiography; Coronary Restenosis; Coronary Thrombosis; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Revascularization; Paclitaxel; Platelet Aggregation Inhibitors; Prospective Studies; Recurrence; Sirolimus; Ticlopidine | 2009 |
Randomized double-blind assessment of the ONSET and OFFSET of the antiplatelet effects of ticagrelor versus clopidogrel in patients with stable coronary artery disease: the ONSET/OFFSET study.
Topics: Adenosine; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Phosphoproteins; Phosphorylation; Platelet Aggregation Inhibitors; Ticagrelor; Ticlopidine; Treatment Outcome | 2009 |
Semi-jailing technique for coil embolization of complex, wide-necked intracranial aneurysms.
Topics: Adult; Aged; Aspirin; Blood Vessel Prosthesis; Cerebral Angiography; Clopidogrel; Embolization, Therapeutic; Female; Humans; Intracranial Aneurysm; Male; Microsurgery; Middle Aged; Platelet Aggregation Inhibitors; Prosthesis Design; Stents; Ticlopidine; Treatment Outcome | 2009 |
Clopidogrel affects leukocyte dependent platelet aggregation by P2Y12 expressing leukocytes.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Female; Humans; Leukocytes; Male; Obesity; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Stents; Ticlopidine | 2010 |
Pantoprazole may enhance antiplatelet effect of enteric-coated aspirin in patients with acute coronary syndrome.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Arachidonic Acid; Aspirin; Clopidogrel; Coronary Angiography; Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Pantoprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Proton Pump Inhibitors; Stents; Tablets, Enteric-Coated; Ticlopidine; Time Factors; Treatment Outcome | 2009 |
Reduction of platelet thromboxane A2 production ex vivo and in vivo by clopidogrel therapy.
Topics: Adolescent; Adult; Aspirin; Blood Platelets; Clopidogrel; Down-Regulation; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thromboxane A2; Thromboxane B2; Ticlopidine; Young Adult | 2010 |
Primary percutaneous coronary angioplasty with and without eptifibatide in ST-segment elevation myocardial infarction: a safety and efficacy study of integrilin-facilitated versus primary percutaneous coronary intervention in ST-segment elevation myocardi
Topics: Administration, Oral; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Drug Administration Schedule; Drug Therapy, Combination; Eptifibatide; Female; Hemorrhage; Heparin; Humans; Infusions, Intravenous; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Ontario; Peptides; Platelet Aggregation Inhibitors; Prospective Studies; Recurrence; Risk Assessment; Ticlopidine; Time Factors; Treatment Outcome | 2009 |
5-year clinical outcomes in the ICTUS (Invasive versus Conservative Treatment in Unstable coronary Syndromes) trial a randomized comparison of an early invasive versus selective invasive management in patients with non-ST-segment elevation acute coronary
Topics: Abciximab; Acute Coronary Syndrome; Adolescent; Adult; Aged; Aged, 80 and over; Angina, Unstable; Antibodies, Monoclonal; Aspirin; Clopidogrel; Coronary Angiography; Electrocardiography; Enoxaparin; Female; Fibrinolytic Agents; Follow-Up Studies; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Myocardial Revascularization; Netherlands; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Survival Rate; Ticlopidine; Time Factors; Treatment Outcome; Young Adult | 2010 |
Assessment of clopidogrel non-response by the PFA-100 system using the new test cartridge INNOVANCE PFA P2Y.
Topics: Aged; Aged, 80 and over; Arterial Occlusive Diseases; Aspirin; Blood Platelets; Catheterization, Peripheral; Clopidogrel; Diagnostic Techniques, Cardiovascular; Female; Fibrinolytic Agents; Hemostasis; Humans; Male; Middle Aged; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Prognosis; Reagent Kits, Diagnostic; Ticlopidine; Treatment Failure | 2010 |
PROCLAIM: pilot study to examine the effects of clopidogrel on inflammatory markers in patients with metabolic syndrome receiving low-dose aspirin.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Aspirin; Atherosclerosis; Biomarkers; C-Reactive Protein; CD40 Ligand; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Inflammation Mediators; Least-Squares Analysis; Male; Metabolic Syndrome; Middle Aged; Natriuretic Peptide, Brain; P-Selectin; Peptide Fragments; Pilot Projects; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome; United States; Young Adult | 2009 |
Comparison of Triple antiplatelet therapy and dual antiplatelet therapy in patients at high risk of restenosis after drug-eluting stent implantation (from the DECLARE-DIABETES and -LONG Trials).
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Clopidogrel; Coronary Restenosis; Diabetes Complications; Drug Therapy, Combination; Drug-Eluting Stents; Female; Follow-Up Studies; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Tetrazoles; Ticlopidine; Treatment Outcome | 2010 |
Reducing cardiac ischemic events in patients with ACS: prasugrel versus clopidogrel. Commentary.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Confidence Intervals; Double-Blind Method; Drug Therapy, Combination; Humans; Myocardial Ischemia; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Pyridines; Thiophenes; Ticlopidine | 2010 |
Evaluation of platelet inhibition by tirofiban in patients stratified according to aspirin and clopidogrel responsiveness: the 3T/2R (Tailoring treatment with tirofiban in patients showing resistance to aspirin and/or resistance to clopidogrel).
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Cohort Studies; Drug Resistance; Humans; Myocardial Infarction; Patient Selection; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine; Tirofiban; Tyrosine | 2010 |
Adding cilostazol to dual antiplatelet therapy achieves greater platelet inhibition than high maintenance dose clopidogrel in patients with acute myocardial infarction: Results of the adjunctive cilostazol versus high maintenance dose clopidogrel in patie
Topics: Adenosine Diphosphate; Aged; Aspirin; Blood Platelets; Blood Vessel Prosthesis Implantation; Cells, Cultured; Chemotherapy, Adjuvant; Cilostazol; Clopidogrel; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Activation; Platelet Aggregation Inhibitors; Prospective Studies; Stents; Tetrazoles; Ticlopidine | 2010 |
Cardioprotective effects of ischemic postconditioning in patients treated with primary percutaneous coronary intervention, evaluated by magnetic resonance.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Cardiotonic Agents; Chemotherapy, Adjuvant; Clopidogrel; Disease Progression; Electrocardiography; Female; Heart Function Tests; Heparin; Humans; Magnetic Resonance Angiography; Male; Middle Aged; Myocardial Infarction; Prospective Studies; Survival Analysis; Ticlopidine | 2010 |
Safety and exploratory efficacy of the novel thrombin receptor (PAR-1) antagonist SCH530348 for non-ST-segment elevation acute coronary syndrome.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Blood Platelets; Clopidogrel; Cohort Studies; Double-Blind Method; Female; Heparin; Humans; Japan; Lactones; Male; Middle Aged; Placebos; Pyridines; Receptor, PAR-1; Ticlopidine | 2010 |
Effect of cilostazol on platelet aggregation in patients with non-ST elevation acute coronary syndrome.
Topics: Acute Coronary Syndrome; Adult; Aged; Aspirin; Cilostazol; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Plasminogen Activator Inhibitor 1; Platelet Aggregation; Platelet Aggregation Inhibitors; Tetrazoles; Ticlopidine | 2010 |
Warfarin after anterior myocardial infarction in current era of dual antiplatelet therapy: a randomized feasibility trial.
Topics: Aged; Anticoagulants; Aspirin; Clopidogrel; Drug Therapy, Combination; Embolism; Feasibility Studies; Female; Hemorrhage; Humans; Incidence; Male; Middle Aged; Myocardial Infarction; Myocardial Revascularization; Ontario; Platelet Aggregation Inhibitors; Recurrence; Stroke; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome; Ultrasonography; Ventricular Dysfunction, Left; Warfarin | 2010 |
In-hospital outcomes of contemporary percutaneous coronary intervention in patients with chronic total occlusion insights from the J-CTO Registry (Multicenter CTO Registry in Japan).
Topics: Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Female; Humans; Inpatients; Japan; Length of Stay; Male; Platelet Aggregation Inhibitors; Prospective Studies; Registries; Stents; Ticlopidine; Time Factors; Treatment Outcome | 2010 |
Modified thromboelastography evaluation of platelet dysfunction in patients undergoing coronary artery surgery.
Topics: Aged; Aspirin; Blood Platelet Disorders; Clopidogrel; Coronary Artery Bypass; Drug Administration Schedule; Epidemiologic Methods; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Preoperative Care; Prognosis; Thrombelastography; Ticlopidine | 2010 |
Effect of combined aspirin and extended-release dipyridamole versus clopidogrel on functional outcome and recurrence in acute, mild ischemic stroke: PRoFESS subgroup analysis.
Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Dipyridamole; Female; Fibrinolytic Agents; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Platelet Aggregation Inhibitors; Recovery of Function; Secondary Prevention; Stroke; Ticlopidine; Treatment Outcome | 2010 |
Remote ischaemic conditioning before hospital admission, as a complement to angioplasty, and effect on myocardial salvage in patients with acute myocardial infarction: a randomised trial.
Topics: Abciximab; Angioplasty, Balloon, Coronary; Angioplasty, Balloon, Laser-Assisted; Antibodies, Monoclonal; Arm; Aspirin; Clopidogrel; Drug Therapy, Combination; Echocardiography; Electrocardiography; Female; Hospitalization; Humans; Immunoglobulin Fab Fragments; Ischemic Preconditioning, Myocardial; Male; Middle Aged; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Platelet Aggregation Inhibitors; Prospective Studies; Radiopharmaceuticals; Technetium Tc 99m Sestamibi; Ticlopidine; Time Factors; Tomography, Emission-Computed, Single-Photon; Treatment Outcome; Troponin T | 2010 |
Duration of dual antiplatelet therapy after implantation of drug-eluting stents.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Disease; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Proportional Hazards Models; Retreatment; Stroke; Thrombosis; Ticlopidine | 2010 |
Clopidogrel plus aspirin versus aspirin alone for reducing embolisation in patients with acute symptomatic cerebral or carotid artery stenosis (CLAIR study): a randomised, open-label, blinded-endpoint trial.
Topics: Adult; Aged; Aspirin; Carotid Artery, Internal; Carotid Stenosis; Clopidogrel; Drug Therapy, Combination; Female; Hong Kong; Humans; Intention to Treat Analysis; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Regression Analysis; Statistics, Nonparametric; Stroke; Ticlopidine; Treatment Outcome; Ultrasonography, Doppler, Transcranial | 2010 |
Systemic low-dose aspirin and clopidogrel independently attenuate reflex cutaneous vasodilation in middle-aged humans.
Topics: Aspirin; Blood Flow Velocity; Clopidogrel; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Reflex; Skin; Skin Physiological Phenomena; Ticlopidine; Vasodilation | 2010 |
Changes in inflammatory biomarkers in patients treated with ticagrelor or clopidogrel.
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Biomarkers; C-Reactive Protein; CD40 Ligand; Clopidogrel; Double-Blind Method; Female; Humans; Interleukin-6; Male; Middle Aged; Peroxidase; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Ticagrelor; Ticlopidine | 2010 |
Effects of polyunsaturated omega-3 fatty acids on responsiveness to dual antiplatelet therapy in patients undergoing percutaneous coronary intervention: the OMEGA-PCI (OMEGA-3 fatty acids after pci to modify responsiveness to dual antiplatelet therapy) st
Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Blood Proteins; Cell Adhesion Molecules; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Fatty Acids, Omega-3; Female; Follow-Up Studies; Humans; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Prognosis; Prospective Studies; Ticlopidine; Treatment Outcome | 2010 |
Pantoprazole does not influence the antiplatelet effect of clopidogrel-a whole blood aggregometry study after coronary stenting.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Interactions; Esomeprazole; Female; Humans; Male; Middle Aged; Multivariate Analysis; Omeprazole; Pantoprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Proton Pump Inhibitors; Regression Analysis; Stents; Ticlopidine | 2010 |
Bleeding complications with dual antiplatelet therapy among patients with stable vascular disease or risk factors for vascular disease: results from the Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management, and Avoidance (CHAR
Topics: Aged; Aspirin; Clopidogrel; Disease Management; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Hemorrhage; Humans; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation Inhibitors; Risk Factors; Survival Rate; Thrombosis; Ticlopidine; Vascular Diseases | 2010 |
Impact of chronic antiplatelet therapy before hospitalization on ischemic and bleeding events in invasively managed patients with acute coronary syndromes: the ACUITY trial.
Topics: Acute Coronary Syndrome; Aged; Anticoagulants; Aspirin; Chi-Square Distribution; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Europe; Female; Hemorrhage; Hospitalization; Humans; Incidence; Kaplan-Meier Estimate; Logistic Models; Male; Middle Aged; Myocardial Infarction; Myocardial Revascularization; New Zealand; Odds Ratio; Platelet Aggregation Inhibitors; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome; United States | 2011 |
Randomized controlled trial of dual antiplatelet therapy in patients undergoing surgery for critical limb ischemia.
Topics: Aged; Amputation, Surgical; Aspirin; Clopidogrel; Double-Blind Method; Female; Flow Cytometry; Hemorrhage; Humans; Ischemia; Leg; Male; Myocardial Infarction; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; Troponin | 2010 |
Effect of clopidogrel on the rate and functional severity of stroke among high vascular risk patients: a prespecified substudy of the Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management and Avoidance (CHARISMA) trial.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Humans; Incidence; Intention to Treat Analysis; Kaplan-Meier Estimate; Male; Platelet Aggregation Inhibitors; Risk Factors; Risk Reduction Behavior; Severity of Illness Index; Stroke; Ticlopidine; Treatment Outcome | 2010 |
The Strategic Reperfusion Early After Myocardial Infarction (STREAM) study.
Topics: Aged; Aspirin; Cardiac Catheterization; Cause of Death; Clopidogrel; Drug Therapy, Combination; Electrocardiography; Enoxaparin; Fibrinolytic Agents; Follow-Up Studies; Humans; Myocardial Infarction; Myocardial Reperfusion; Platelet Aggregation Inhibitors; Prospective Studies; Survival Rate; Thrombolytic Therapy; Ticlopidine; Time Factors; Treatment Outcome | 2010 |
Incidence of dyspnea and assessment of cardiac and pulmonary function in patients with stable coronary artery disease receiving ticagrelor, clopidogrel, or placebo in the ONSET/OFFSET study.
Topics: Adenosine; Aged; Aspirin; Clopidogrel; Coronary Disease; Double-Blind Method; Dyspnea; Female; Heart; Humans; Lung; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Ticagrelor; Ticlopidine | 2010 |
[Impact of application time of aspirin and clopidogrel on platelet aggregation in patients with acute coronary syndrome].
Topics: Acute Coronary Syndrome; Adult; Aged; Aspirin; Circadian Rhythm; Clopidogrel; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine; Time Factors | 2010 |
[Glycoprotein IIb-IIIa antagonist Monafram in primary angioplasty of patients with acute coronary syndrome without st segment elevation].
Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clopidogrel; Electrocardiography; Female; Fibrinolytic Agents; Hemorrhage; Heparin; Humans; Injections, Intravenous; Male; Middle Aged; Myocardial Infarction; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Risk Factors; Secondary Prevention; Thrombocytopenia; Ticlopidine; Treatment Outcome | 2010 |
A randomised determination of the Effect of Fluvastatin and Atorvastatin on top of dual antiplatelet treatment on platelet aggregation after implantation of coronary drug-eluting stents. The EFA-Trial.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Atorvastatin; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Drug Interactions; Drug Therapy, Combination; Drug-Eluting Stents; Fatty Acids, Monounsaturated; Female; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Prosthesis Design; Pyrroles; Switzerland; Ticlopidine; Time Factors; Treatment Outcome | 2010 |
Intra-individual variability in clopidogrel responsiveness in coronary artery disease patients under long term therapy.
Topics: Aspirin; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Female; Humans; Individuality; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine | 2010 |
Results of the randomized, placebo-controlled clopidogrel and acetylsalicylic acid in bypass surgery for peripheral arterial disease (CASPAR) trial.
Topics: Aged; Amputation, Surgical; Aspirin; Australia; Blood Vessel Prosthesis Implantation; Chi-Square Distribution; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Europe; Female; Graft Occlusion, Vascular; Hemorrhage; Humans; Kaplan-Meier Estimate; Lower Extremity; Male; Middle Aged; Peripheral Vascular Diseases; Placebo Effect; Platelet Aggregation Inhibitors; Proportional Hazards Models; Prospective Studies; Reoperation; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome; Vascular Patency; Veins | 2010 |
Mortality predictors and effects of antithrombotic therapies in atrial fibrillation: insights from ACTIVE-W.
Topics: Aspirin; Atrial Fibrillation; Biphenyl Compounds; Clopidogrel; Drug Therapy, Combination; Fibrinolytic Agents; Hemorrhage; Humans; Irbesartan; Kaplan-Meier Estimate; Platelet Aggregation Inhibitors; Risk Factors; Stroke; Tetrazoles; Ticlopidine; Treatment Outcome; Vitamin K | 2010 |
Is gastroduodenal biopsy safe in patients receiving aspirin and clopidogrel?: a prospective, randomized study involving 630 biopsies.
Topics: Adult; Aspirin; Biopsy; Clopidogrel; Duodenum; Endoscopy, Digestive System; Female; Gastrointestinal Hemorrhage; Humans; Male; Platelet Aggregation Inhibitors; Pyloric Antrum; Risk Factors; Single-Blind Method; Ticlopidine | 2011 |
Randomised controlled trial evaluating the role of tirofiban in high-risk non-ST elevation acute coronary syndromes: an East Indian perspective.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Electrocardiography; Emergency Service, Hospital; Enoxaparin; Female; Follow-Up Studies; Humans; India; Kaplan-Meier Estimate; Male; Middle Aged; Platelet Aggregation Inhibitors; Reference Values; Severity of Illness Index; Survival Rate; Ticlopidine; Tirofiban; Treatment Outcome; Tyrosine | 2010 |
Study design and rationale of 'Influence of Cilostazol-based triple anti-platelet therapy on ischemic complication after drug-eluting stent implantation (CILON-T)' study: A multicenter randomized trial evaluating the efficacy of Cilostazol on ischemic vas
Topics: Angioplasty, Balloon, Coronary; Aspirin; Brain Ischemia; Cilostazol; Clinical Protocols; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Myocardial Infarction; Myocardial Ischemia; Platelet Aggregation Inhibitors; Prospective Studies; Prosthesis Design; Republic of Korea; Research Design; Stroke; Tetrazoles; Ticlopidine; Time Factors; Treatment Outcome | 2010 |
Comparison between the effect of omeprazole and rabeprazole on the antiplatelet action of clopidogrel.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Diphosphate; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Interactions; Enzyme Inhibitors; Female; Humans; Male; Middle Aged; Omeprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabeprazole; Ticlopidine; Treatment Outcome | 2010 |
Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute coronary syndromes (CURRENT-OASIS 7): a randomised factorial trial.
Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Female; Humans; Male; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine | 2010 |
Dose comparisons of clopidogrel and aspirin in acute coronary syndromes.
Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Combined Modality Therapy; Coronary Angiography; Coronary Artery Bypass; Double-Blind Method; Female; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Research Design; Stroke; Ticlopidine | 2010 |
Rationale and design of a randomized, double-blind trial comparing the effects of a 3-month clopidogrel-aspirin regimen versus aspirin alone for the treatment of high-risk patients with acute nondisabling cerebrovascular event.
Topics: Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Humans; Intention to Treat Analysis; Ischemic Attack, Transient; Outcome Assessment, Health Care; Patient Selection; Platelet Aggregation Inhibitors; Research Design; Risk Assessment; Sample Size; Stroke; Ticlopidine | 2010 |
The efficacy and safety of clopidogrel in vascular surgery patients with immediate postoperative asymptomatic troponin T release for the prevention of late cardiac events: Rationale and design of the Dutch Echocardiographic Cardiac Risk Evaluation Applyin
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Echocardiography, Stress; Humans; Myocardial Infarction; Myocardial Ischemia; Netherlands; Platelet Aggregation Inhibitors; Postoperative Care; Postoperative Complications; Research Design; Ticlopidine; Troponin T; Vascular Surgical Procedures | 2010 |
Enhanced platelet inhibition by adjunctive cilostazol to dual antiplatelet therapy after drug-eluting stent implantation for complex lesions.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Clopidogrel; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Stents; Tetrazoles; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2010 |
[Implantation of the paclitaxel-eluting stent Apollo in patients with stable angina pectoris: long-term angiographic and clinical results].
Topics: Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Restenosis; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Male; Middle Aged; Paclitaxel; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2010 |
Prehospital triple antiplatelet therapy in patients with acute ST elevation myocardial infarction leads to better platelet aggregation inhibition and clinical outcome than dual antiplatelet therapy.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Combined Modality Therapy; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine; Tirofiban; Treatment Outcome; Tyrosine | 2010 |
Clopidogrel with or without omeprazole in coronary artery disease.
Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Drug Interactions; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine | 2010 |
Long-term clinical outcome based on aspirin and clopidogrel responsiveness status after elective percutaneous coronary intervention: a 3T/2R (tailoring treatment with tirofiban in patients showing resistance to aspirin and/or resistance to clopidogrel) tr
Topics: Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Resistance; Elective Surgical Procedures; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Predictive Value of Tests; Prospective Studies; Ticlopidine; Time Factors; Tirofiban; Treatment Outcome; Tyrosine | 2010 |
[Impact of different proton pump inhibitors on the antiplatelet activity of clopidogrel in combination with aspirin for patients undergoing coronary stent implantation].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Angioplasty, Balloon; Aspirin; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Omeprazole; Pantoprazole; Platelet Aggregation; Postoperative Period; Proton Pump Inhibitors; Stents; Ticlopidine | 2010 |
Aspirin plus clopidogrel therapy increases early venous graft patency after coronary artery bypass surgery a single-center, randomized, controlled trial.
Topics: Administration, Oral; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease; Drug Therapy, Combination; Electrocardiography; Female; Follow-Up Studies; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Saphenous Vein; Ticlopidine; Time Factors; Tomography, X-Ray Computed; Treatment Outcome; Vascular Patency | 2010 |
First analysis of the relation between CYP2C19 genotype and pharmacodynamics in patients treated with ticagrelor versus clopidogrel: the ONSET/OFFSET and RESPOND genotype studies.
Topics: Adenosine; Aged; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Double-Blind Method; Genotype; Humans; Male; Middle Aged; Pharmacokinetics; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Purinergic P2Y Receptor Antagonists; Ticagrelor; Ticlopidine | 2010 |
Effect of omeprazole on the concentration of interleukin-6 and transforming growth factor-β1 in patients receiving dual antiplatelet therapy after percutaneous coronary intervention.
Topics: Aged; Anti-Ulcer Agents; Aspirin; Biomarkers; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Gene Expression Regulation; Humans; Interleukin-6; Male; Middle Aged; Omeprazole; Platelet Aggregation Inhibitors; Predictive Value of Tests; Ticlopidine; Transforming Growth Factor beta1; Treatment Outcome | 2010 |
Aspirin plus clopidogrel versus aspirin alone after coronary artery bypass grafting: the clopidogrel after surgery for coronary artery disease (CASCADE) Trial.
Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Double-Blind Method; Drug Therapy, Combination; Female; Hemorrhage; Humans; Hyperplasia; Incidence; Male; Middle Aged; Platelet Aggregation Inhibitors; Saphenous Vein; Ticlopidine; Treatment Outcome; Tunica Intima; Ultrasonography, Interventional | 2010 |
Randomized trial of aspirin and clopidogrel versus aspirin alone for the prevention of coronary artery bypass graft occlusion: the Preoperative Aspirin and Postoperative Antiplatelets in Coronary Artery Bypass Grafting study.
Topics: Aged; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Double-Blind Method; Female; Follow-Up Studies; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Myocardial Ischemia; Pilot Projects; Platelet Aggregation Inhibitors; Postoperative Care; Preoperative Care; Prospective Studies; Ticlopidine; Treatment Outcome | 2010 |
Cilostazol reduces the progression of carotid intima-media thickness without increasing the risk of bleeding in patients with acute coronary syndrome during a 2-year follow-up.
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Analysis of Variance; Angioplasty, Balloon, Coronary; Anti-Inflammatory Agents; Aspirin; Carotid Arteries; Carotid Stenosis; Chi-Square Distribution; Cilostazol; Clopidogrel; Coronary Angiography; Disease Progression; Drug Therapy, Combination; Hemorrhage; Humans; Inflammation Mediators; Middle Aged; Phosphodiesterase 3 Inhibitors; Platelet Aggregation Inhibitors; Prospective Studies; Republic of Korea; Risk Assessment; Risk Factors; Single-Blind Method; Stents; Tetrazoles; Ticlopidine; Time Factors; Treatment Outcome; Tunica Intima; Tunica Media; Ultrasonography | 2011 |
Randomized comparison of platelet function monitoring to adjust antiplatelet therapy versus standard of care: rationale and design of the assessment with a double randomization of (1) a fixed dose versus a monitoring-guided dose of aspirin and clopidogrel
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Male; Monitoring, Physiologic; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine; Time Factors; Treatment Outcome | 2011 |
A randomized pilot trial for aggressive therapeutic approaches in aspirin-resistant patients undergoing percutaneous coronary intervention.
Topics: Adult; Angioplasty, Balloon, Coronary; Antithrombins; Aspirin; Blood Platelets; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Female; Hirudins; Humans; Male; Middle Aged; Peptide Fragments; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Recombinant Proteins; Ticlopidine | 2011 |
Effect of clopidogrel plus ASA vs. ASA early after TIA and ischaemic stroke: a substudy of the CHARISMA trial.
Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Ischemic Attack, Transient; Kaplan-Meier Estimate; Male; Middle Aged; Platelet Aggregation Inhibitors; Prognosis; Sample Size; Ticlopidine; Treatment Outcome | 2011 |
Non-invasive alternating current stimulation induces recovery from stroke.
Topics: Aged; Aphasia; Aspirin; Brain Ischemia; Clopidogrel; Combined Modality Therapy; Electric Stimulation Therapy; Electroencephalography; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Recovery of Function; Severity of Illness Index; Stroke; Stroke Rehabilitation; Ticlopidine; Treatment Outcome | 2010 |
Tailored antiplatelet therapy can overcome clopidogrel and aspirin resistance--the BOchum CLopidogrel and Aspirin Plan (BOCLA-Plan) to improve antiplatelet therapy.
Topics: Aspirin; Clopidogrel; Demography; Drug Resistance; Female; Humans; Male; Middle Aged; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Receptors, Purinergic P2; Risk Factors; Thiophenes; Ticlopidine | 2011 |
Multicenter randomized trial evaluating the efficacy of cilostazol on ischemic vascular complications after drug-eluting stent implantation for coronary heart disease: results of the CILON-T (influence of CILostazol-based triple antiplatelet therapy ON is
Topics: Aged; Aspirin; Brain Ischemia; Cilostazol; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Postoperative Complications; Prospective Studies; Tetrazoles; Ticlopidine; Treatment Outcome | 2011 |
A pharmacodynamic comparison of prasugrel vs. high-dose clopidogrel in patients with type 2 diabetes mellitus and coronary artery disease: results of the Optimizing anti-Platelet Therapy In diabetes MellitUS (OPTIMUS)-3 Trial.
Topics: Adolescent; Adult; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Cross-Over Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Double-Blind Method; Female; Humans; Male; Middle Aged; Piperazines; Platelet Activation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Prospective Studies; Thiophenes; Ticlopidine; Treatment Outcome; Young Adult | 2011 |
Clopidogrel versus dipyridamole in addition to aspirin in reducing embolization detected with ambulatory transcranial Doppler: a randomized trial.
Topics: Aged; Aged, 80 and over; Ambulatory Care; Aspirin; Clopidogrel; Dipyridamole; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Stroke; Ticlopidine; Ultrasonography, Doppler, Transcranial | 2011 |
Safety of clopidogrel in older patients: a nonrandomized, parallel-group, controlled, two-centre study.
Topics: Acute Coronary Syndrome; Administration, Cutaneous; Age Factors; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Prospective Studies; Stents; Stroke; Thrombocytopenia; Ticlopidine; Treatment Outcome | 2011 |
Cilostazol attenuates on-treatment platelet reactivity in patients with CYP2C19 loss of function alleles receiving dual antiplatelet therapy: a genetic substudy of the CILON-T randomised controlled trial.
Topics: Aged; Alleles; Aryl Hydrocarbon Hydroxylases; Aspirin; Cardiovascular Diseases; Cilostazol; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Drug-Eluting Stents; Epidemiologic Methods; Female; Humans; Korea; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Tetrazoles; Ticlopidine; Treatment Outcome | 2011 |
The Secondary Prevention of Small Subcortical Strokes (SPS3) study.
Topics: Antihypertensive Agents; Aspirin; Clopidogrel; Cognition Disorders; Humans; Hypertension; Magnetic Resonance Imaging; Platelet Aggregation Inhibitors; Research Design; Secondary Prevention; Stroke; Ticlopidine | 2011 |
A case-control study on platelet reactivity in patients with coronary stent thrombosis.
Topics: Aged; Aspirin; Blood Platelets; Case-Control Studies; Clopidogrel; Coronary Thrombosis; Female; Flow Cytometry; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Function Tests; Stents; Ticlopidine; Treatment Outcome; Vasodilator Agents | 2011 |
A randomized, double-blind, multicenter comparison study of triple antiplatelet therapy with dual antiplatelet therapy to reduce restenosis after drug-eluting stent implantation in long coronary lesions: results from the DECLARE-LONG II (Drug-Eluting Sten
Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Double-Blind Method; Drug Therapy, Combination; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Radiography; Tetrazoles; Ticlopidine; Treatment Outcome | 2011 |
High-sensitivity C-reactive protein and clopidogrel treatment in patients at high risk of cardiovascular events: a substudy from the CHARISMA trial.
Topics: Aged; Aspirin; Atherosclerosis; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Epidemiologic Methods; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2011 |
Trans-radial approach for catheterisation in non-ST segment elevation acute coronary syndrome: an analysis of major bleeding complications in the ABOARD Study.
Topics: Abciximab; Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Hemorrhage; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2011 |
Long-term reduction of mortality in the 4-year follow up of tirofiban therapy in elective percutaneous coronary interventions (TOPSTAR) trial.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Restenosis; Drug Therapy, Combination; Female; Fibrinolytic Agents; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Longitudinal Studies; Male; Middle Aged; Myocardial Infarction; Platelet Glycoprotein GPIIb-IIIa Complex; Survival Rate; Ticlopidine; Tirofiban; Treatment Outcome; Troponin; Tyrosine | 2011 |
High on-treatment platelet reactivity to both aspirin and clopidogrel is associated with the highest risk of adverse events following percutaneous coronary intervention.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Atherosclerosis; Clopidogrel; Drug Therapy, Combination; Female; Graft Occlusion, Vascular; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation Inhibitors; Risk Factors; Stents; Stroke; Thrombosis; Ticlopidine; Treatment Outcome | 2011 |
Platelet inhibition by adjunctive cilostazol versus high maintenance-dose clopidogrel in patients with acute myocardial infarction according to cytochrome P450 2C19 genotype.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Aspirin; Chi-Square Distribution; Cilostazol; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Female; Genotype; Humans; Korea; Liver; Male; Middle Aged; Myocardial Infarction; Phenotype; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Regression Analysis; Risk Assessment; Risk Factors; Tetrazoles; Thrombosis; Ticlopidine; Treatment Outcome | 2011 |
Omeprazole affects clopidogrel efficacy but not ischemic events in patients with acute coronary syndrome undergoing elective percutaneous coronary intervention.
Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Female; Humans; Male; Middle Aged; Omeprazole; Platelet Aggregation Inhibitors; Ticlopidine | 2011 |
The effects of laropiprant, a selective prostaglandin D₂ receptor 1 antagonist, on the antiplatelet activity of clopidogrel or aspirin.
Topics: Adolescent; Adult; Aspirin; Bleeding Time; Blood Platelets; Clopidogrel; Female; Humans; Indoles; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Immunologic; Receptors, Prostaglandin; Ticlopidine; Young Adult | 2011 |
Dabigatran vs. placebo in patients with acute coronary syndromes on dual antiplatelet therapy: a randomized, double-blind, phase II trial.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Benzimidazoles; beta-Alanine; Clopidogrel; Dabigatran; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Fibrin Fibrinogen Degradation Products; Fibrinolytic Agents; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Prospective Studies; Recurrence; Ticlopidine; Treatment Outcome | 2011 |
Platelet response to aspirin and clopidogrel in patients with peripheral atherosclerosis.
Topics: Aged; Aspirin; Atherosclerosis; Blood Platelets; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine; Treatment Outcome | 2011 |
A randomized two-by-two comparison of high-dose bolus tirofiban versus abciximab and unfractionated heparin versus bivalirudin during percutaneous coronary revascularization and stent placement: the tirofiban evaluation of novel dosing versus abciximab wi
Topics: Abciximab; Aged; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Antithrombins; Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Hemorrhage; Heparin; Hirudins; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Recombinant Proteins; Risk Assessment; Risk Factors; Stents; Ticlopidine; Time Factors; Tirofiban; Treatment Outcome; Tyrosine; United States | 2011 |
Predictors of bleeding and time dependence of association of bleeding with mortality: insights from the Trial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet Inhibition With Prasugrel--Thrombolysis in Myocardial Infarction 38 (TRITON-
Topics: Aged; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Predictive Value of Tests; Proportional Hazards Models; Purinergic P2Y Receptor Antagonists; Risk Factors; Thiophenes; Thrombolytic Therapy; Ticlopidine | 2011 |
Impact of adjunctive cilostazol therapy on platelet function profiles in patients with and without diabetes mellitus on aspirin and clopidogrel therapy.
Topics: Aged; Aspirin; Blood Platelets; Chemotherapy, Adjuvant; Cilostazol; Clopidogrel; Cross-Over Studies; Diabetes Mellitus; Double-Blind Method; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Receptors, Purinergic P2Y12; Signal Transduction; Tetrazoles; Thrombin; Ticlopidine | 2011 |
Reduced thrombin formation and altered fibrin clot properties induced by polyunsaturated omega-3 fatty acids on top of dual antiplatelet therapy in patients undergoing percutaneous coronary intervention (OMEGA-PCI clot).
Topics: Aged; Analysis of Variance; Angioplasty, Balloon, Coronary; Aspirin; Biomarkers; Blood Coagulation; C-Reactive Protein; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Dinoprost; Double-Blind Method; Down-Regulation; Drug Therapy, Combination; Fatty Acids, Omega-3; Female; Fibrin; Humans; Linear Models; Male; Middle Aged; Oxidative Stress; Peptide Fragments; Platelet Aggregation; Platelet Aggregation Inhibitors; Poland; Prospective Studies; Prothrombin; Thrombin; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2011 |
Insights into the inhibition of platelet activation by omega-3 polyunsaturated fatty acids: beyond aspirin and clopidogrel.
Topics: Adult; Aspirin; Bleeding Time; Blood Platelets; Chi-Square Distribution; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fatty Acids, Omega-3; Female; Hemorrhage; Humans; Male; Middle Aged; North Carolina; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Surface Properties; Ticlopidine; Time Factors | 2011 |
Randomized double-blind placebo-controlled crossover study to determine the effects of esomeprazole on inhibition of platelet function by clopidogrel.
Topics: Acute Coronary Syndrome; Aged; Aryl Hydrocarbon Hydroxylases; Aspirin; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Cross-Over Studies; Cytochrome P-450 CYP2C19; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Esomeprazole; Female; Genotype; Humans; Male; Microfilament Proteins; Middle Aged; Phenotype; Phosphoproteins; Placebo Effect; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Proton Pump Inhibitors; Risk Assessment; Ticlopidine; Time Factors; Victoria | 2011 |
Ticagrelor compared with clopidogrel by geographic region in the Platelet Inhibition and Patient Outcomes (PLATO) trial.
Topics: Adenosine; Aged; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Global Health; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Proportional Hazards Models; Purinergic P2Y Receptor Antagonists; Risk Factors; Stroke; Ticagrelor; Ticlopidine; United States | 2011 |
Randomised clinical trial: rabeprazole plus aspirin is not inferior to rabeprazole plus clopidogrel for the healing of aspirin-related peptic ulcer.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Aged, 80 and over; Anti-Ulcer Agents; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Peptic Ulcer; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Rabeprazole; Regression Analysis; Ticlopidine; Treatment Outcome | 2011 |
Combined clopidogrel and proton pump inhibitor therapy is associated with higher cardiovascular event rates after percutaneous coronary intervention: a report from the BASKET trial.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Retrospective Studies; Risk Factors; Ticlopidine | 2012 |
The effect of ticagrelor versus clopidogrel on high on-treatment platelet reactivity: combined analysis of the ONSET/OFFSET and RESPOND studies.
Topics: Adenosine; Administration, Oral; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Retrospective Studies; Ticagrelor; Ticlopidine; Time Factors; Treatment Outcome | 2011 |
Higher efficacy of pre-hospital tirofiban with longer pre-treatment time to primary PCI: protection for the negative impact of time delay.
Topics: Aged; Ambulances; Angioplasty, Balloon, Coronary; Aspirin; Chi-Square Distribution; Clopidogrel; Coronary Angiography; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Emergency Medical Services; Female; Fibrinolytic Agents; Health Services Accessibility; Heparin; Humans; Logistic Models; Male; Middle Aged; Myocardial Infarction; Netherlands; Outcome and Process Assessment, Health Care; Platelet Aggregation Inhibitors; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Tirofiban; Treatment Outcome; Tyrosine | 2011 |
Doubling the dose of clopidogrel restores the loss of antiplatelet effect induced by esomeprazole.
Topics: Aged; Anti-Ulcer Agents; Aspirin; Clopidogrel; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Esomeprazole; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Function Tests; Ranitidine; Ticlopidine | 2011 |
Comparison of antiplatelet effect and tolerability of clopidogrel resinate with clopidogrel bisulfate in patients with coronary heart disease (CHD) or CHD-equivalent risks: a phase IV, prospective, double-dummy, parallel-group, 4-week noninferiority trial
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Coronary Disease; Double-Blind Method; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Point-of-Care Systems; Prospective Studies; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Ticlopidine | 2011 |
Effect of hydroxyethyl starch 130/0.4 on blood loss and coagulation in patients with recent exposure to dual antiplatelet therapy undergoing off-pump coronary artery bypass graft surgery.
Topics: Aged; Aspirin; Blood Coagulation; Blood Loss, Surgical; Clopidogrel; Coronary Artery Bypass, Off-Pump; Crystalloid Solutions; Female; Hemoglobins; Hemorrhage; Humans; Hydroxyethyl Starch Derivatives; Isotonic Solutions; Male; Middle Aged; Perioperative Care; Plasma Substitutes; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2011 |
Impact of pentoxifylline on platelet function profiles in patients with type 2 diabetes mellitus and coronary artery disease on dual antiplatelet therapy with aspirin and clopidogrel.
Topics: Aged; Aspirin; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Florida; Humans; Male; Microfilament Proteins; Middle Aged; Pentoxifylline; Phosphodiesterase Inhibitors; Phosphoproteins; Phosphorylation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Receptors, Purinergic P2Y12; Ticlopidine; Time Factors; Treatment Outcome | 2011 |
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
Topics: Aged; Antihypertensive Agents; Aspirin; Clopidogrel; Combined Modality Therapy; Female; Follow-Up Studies; Health Behavior; Humans; Intracranial Arteriosclerosis; Intracranial Hemorrhages; Ischemic Attack, Transient; Kaplan-Meier Estimate; Male; Middle Aged; Platelet Aggregation Inhibitors; Stents; Stroke; Ticlopidine | 2011 |
Dual antiplatelet therapy versus aspirin alone in patients undergoing transcatheter aortic valve implantation.
Topics: Aged, 80 and over; Aortic Valve; Aortic Valve Stenosis; Aspirin; Catheters; Clopidogrel; Drug Therapy, Combination; Female; Heart Valve Prosthesis Implantation; Humans; Male; Platelet Aggregation Inhibitors; Severity of Illness Index; Single-Blind Method; Ticlopidine | 2011 |
A randomized clinical trial comparing point-of-care platelet function assays and bleeding time in healthy subjects treated with aspirin or clopidogrel.
Topics: Adult; Aryl Hydrocarbon Hydroxylases; Aspirin; Bleeding Time; Clopidogrel; Cross-Over Studies; Cytochrome P-450 CYP2C19; Female; Genotype; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Ticlopidine; Young Adult | 2012 |
Spot drug-eluting stenting for long coronary stenoses: long-term results of a randomized clinical study.
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coronary Angiography; Coronary Restenosis; Drug-Eluting Stents; Enoxaparin; Female; Humans; Male; Proportional Hazards Models; Risk Assessment; Severity of Illness Index; Ticlopidine; Time Factors; Ultrasonography, Interventional | 2011 |
Optimal timing of discontinuation of clopidogrel and risk of blood transfusion after coronary surgery. Propensity score analysis.
Topics: Aged; Aspirin; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedures; Clopidogrel; Female; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Preoperative Care; Risk Factors; Ticlopidine | 2011 |
Net clinical benefit of adding clopidogrel to aspirin therapy in patients with atrial fibrillation for whom vitamin K antagonists are unsuitable.
Topics: Aspirin; Atrial Fibrillation; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Proportional Hazards Models; Sensitivity and Specificity; Stroke; Ticlopidine; Vitamin K | 2011 |
Pharmacodynamic evaluation of clopidogrel plus PA32540: the Spaced PA32540 With Clopidogrel Interaction Gauging (SPACING) study.
Topics: Adult; Anti-Ulcer Agents; Aspirin; Clopidogrel; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Drug Interactions; Female; Humans; Least-Squares Analysis; Male; Omeprazole; Platelet Aggregation Inhibitors; Tablets, Enteric-Coated; Ticlopidine | 2011 |
A novel regimen of alternate day clopidogrel would provide a cost-effective strategy to prevent very late stent thrombosis.
Topics: Aspirin; Clopidogrel; Cohort Studies; Coronary Thrombosis; Drug-Eluting Stents; Equipment Safety; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2012 |
Evaluating the safety of very short-term (10 days) dual antiplatelet therapy after Genous™ bio-engineered R stent™ implantation: the multicentre pilot Genous trial.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Stenosis; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Italy; Male; Middle Aged; Myocardial Infarction; Pilot Projects; Platelet Aggregation Inhibitors; Prospective Studies; Prosthesis Design; Severity of Illness Index; Stents; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2011 |
Bleeding complications with the P2Y12 receptor antagonists clopidogrel and ticagrelor in the PLATelet inhibition and patient Outcomes (PLATO) trial.
Topics: Acute Coronary Syndrome; Adenosine; Aged; Aspirin; Clopidogrel; Coronary Artery Bypass; Double-Blind Method; Female; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Stroke; Ticagrelor; Ticlopidine; Treatment Outcome | 2011 |
Esomeprazole compared with famotidine in the prevention of upper gastrointestinal bleeding in patients with acute coronary syndrome or myocardial infarction.
Topics: Acute Coronary Syndrome; Aged; Anti-Ulcer Agents; Aspirin; Chi-Square Distribution; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Enoxaparin; Esomeprazole; Famotidine; Female; Fibrinolytic Agents; Follow-Up Studies; Gastrointestinal Hemorrhage; Humans; Intestinal Perforation; Male; Middle Aged; Platelet Aggregation Inhibitors; Proportional Hazards Models; Ticlopidine; Treatment Outcome | 2012 |
[Tirofiban improved the prognosis of senior acute coronary syndrome patients received percutaneous coronary intervention].
Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prognosis; Ticlopidine; Tirofiban; Tyrosine | 2011 |
The effect of pre-hospital glycoprotein IIb-IIIa inhibitors on angiographic outcome in STEMI patients who are candidates for primary PCI.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Circulation; Coronary Thrombosis; Drug Administration Schedule; Drug Therapy, Combination; Emergency Medical Services; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Predictive Value of Tests; Prospective Studies; Severity of Illness Index; Ticlopidine; Time Factors; Tirofiban; Treatment Outcome; Tyrosine; Vascular Patency | 2012 |
Pharmacodynamic assessment of a novel P2Y12 receptor antagonist in Japanese patients with coronary artery disease undergoing elective percutaneous coronary intervention.
Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Double-Blind Method; Female; Humans; Japan; Male; Middle Aged; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Thiophenes; Ticlopidine; Young Adult | 2012 |
Six-month versus 12-month dual antiplatelet therapy after implantation of drug-eluting stents: the Efficacy of Xience/Promus Versus Cypher to Reduce Late Loss After Stenting (EXCELLENT) randomized, multicenter study.
Topics: Aged; Aspirin; Clopidogrel; Combined Modality Therapy; Coronary Disease; Coronary Restenosis; Drug Therapy, Combination; Drug-Eluting Stents; Female; Follow-Up Studies; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Prospective Studies; Risk Factors; Ticlopidine; Treatment Outcome | 2012 |
The pattern of platelet response to clopidogrel in Iranian patients after percutaneous coronary intervention.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Cross-Sectional Studies; Dose-Response Relationship, Drug; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Iran; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors | 2012 |
Antiplatelet therapy for prevention of thromboembolic complications associated with coil embolization of unruptured cerebral aneurysms.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cerebral Angiography; Clopidogrel; Embolization, Therapeutic; Female; Humans; Incidence; Intracranial Aneurysm; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Retrospective Studies; Thromboembolism; Ticlopidine; Treatment Outcome; Young Adult | 2012 |
Impact of platelet reactivity to adenosine diphosphate before implantation of drug-eluting stents on subsequent adverse cardiac events in patients with stable angina.
Topics: Adenosine Diphosphate; Aged; Aged, 80 and over; Angina, Stable; Aspirin; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2012 |
Risk of recurrent stroke in patients with silent brain infarction in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) imaging substudy.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Aspirin; Benzimidazoles; Benzoates; Brain Ischemia; Cerebral Infarction; Clopidogrel; Dipyridamole; Female; Humans; Intracranial Embolism; Kaplan-Meier Estimate; Magnetic Resonance Imaging; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Secondary Prevention; Socioeconomic Factors; Stroke; Telmisartan; Ticlopidine; Tomography, X-Ray Computed; Treatment Outcome; Vasodilator Agents | 2012 |
Reversal of the anti-platelet effects of aspirin and clopidogrel.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Aspirin; Biomarkers; Blood Platelets; Clopidogrel; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Ontario; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Transfusion; Recovery of Function; Thromboxane B2; Ticlopidine; Time Factors | 2012 |
[Branch atheromatous disease: prognosis and management. The SPS3 experience].
Topics: Aspirin; Basilar Artery; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Stroke; Stroke, Lacunar; Ticlopidine | 2011 |
Description of response to aspirin and clopidogrel in outpatients with coronary artery disease using multiple electrode impedance aggregometry.
Topics: Adult; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Placental Function Tests; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2012 |
Net clinical benefit of prehospital glycoprotein IIb/IIIa inhibitors in patients with ST-elevation myocardial infarction and high risk of bleeding: effect of tirofiban in patients at high risk of bleeding using CRUSADE bleeding score.
Topics: Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Bypass; Double-Blind Method; Electrocardiography; Emergency Medical Services; Female; Hemorrhage; Heparin; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prevalence; Retrospective Studies; Risk Factors; Ticlopidine; Tirofiban; Treatment Outcome; Tyrosine | 2012 |
Loading effect of 200 mg cilostazol on platelet inhibition in patients undergoing percutaneous coronary intervention.
Topics: Adult; Aged; Aspirin; Cilostazol; Clopidogrel; Endovascular Procedures; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Tetrazoles; Ticlopidine | 2012 |
Closure or medical therapy for cryptogenic stroke with patent foramen ovale.
Topics: Adolescent; Adult; Anticoagulants; Aspirin; Clopidogrel; Combined Modality Therapy; Drug Therapy, Combination; Embolism, Paradoxical; Female; Foramen Ovale, Patent; Humans; Ischemic Attack, Transient; Kaplan-Meier Estimate; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Prostheses and Implants; Secondary Prevention; Stroke; Ticlopidine; Warfarin; Young Adult | 2012 |
Pharmacodynamic effects of adjunctive cilostazol therapy in patients with coronary artery disease on dual antiplatelet therapy: impact of high on-treatment platelet reactivity and diabetes mellitus status.
Topics: Aged; Aspirin; Blood Platelets; Cilostazol; Clopidogrel; Coronary Artery Disease; Cross-Over Studies; Diabetic Angiopathies; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Radiography; Risk Assessment; Statistics, Nonparametric; Survival Analysis; Tetrazoles; Ticlopidine; Treatment Outcome | 2013 |
Short- versus long-term duration of dual-antiplatelet therapy after coronary stenting: a randomized multicenter trial.
Topics: Aged; Aged, 80 and over; Aspirin; Cause of Death; Clopidogrel; Coronary Restenosis; Coronary Vessels; Drug Therapy, Combination; Drug-Eluting Stents; Everolimus; Female; Humans; Male; Middle Aged; Myocardial Infarction; Paclitaxel; Platelet Aggregation Inhibitors; Risk; Sirolimus; Stroke; Thrombosis; Ticlopidine; Treatment Outcome | 2012 |
Prophylactic use of clopidogrel in paediatric cardiac patients.
Topics: Aspirin; Child; Child, Preschool; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Heart Defects, Congenital; Humans; Infant; Male; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Thromboembolism; Ticlopidine | 2012 |
Predicting the risk of symptomatic intracerebral hemorrhage in ischemic stroke treated with intravenous alteplase: safe Implementation of Treatments in Stroke (SITS) symptomatic intracerebral hemorrhage risk score.
Topics: Age Factors; Aged; Aspirin; Body Weight; Brain Ischemia; Cerebral Hemorrhage; Clopidogrel; Female; Fibrinolytic Agents; Humans; Hypertension; Injections, Intravenous; Logistic Models; Male; Middle Aged; Platelet Aggregation Inhibitors; Predictive Value of Tests; Registries; Risk Factors; Stroke; Ticlopidine; Tissue Plasminogen Activator | 2012 |
[Changes in coagulation and fibrinolysis in the patients with coronary heart disease in acute period and effect of drug intervention].
Topics: Adult; Aged; Aged, 80 and over; Angina, Unstable; Aspirin; Blood Coagulation; Case-Control Studies; Clopidogrel; Coronary Disease; Double-Blind Method; Female; Fibrin Fibrinogen Degradation Products; Fibrinolysis; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Activating Factor; Prospective Studies; Ticlopidine; Tissue Plasminogen Activator; von Willebrand Factor | 2012 |
Earlier application of loading doses of aspirin and clopidogrel decreases rate of recurrent cardiovascular ischemic events for patients undergoing percutaneous coronary intervention.
Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Thrombelastography; Thrombosis; Ticlopidine | 2012 |
[Effects of intensive antiplatelet therapy for patients with high on-treatment platelet reactivity after coronary stent implantation].
Topics: Acute Coronary Syndrome; Adult; Aged; Aspirin; Blood Platelets; Cilostazol; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Tetrazoles; Ticlopidine | 2012 |
Accelerated platelet inhibition by switching from atorvastatin to a non-CYP3A4-metabolized statin in patients with high platelet reactivity (ACCEL-STATIN) study.
Topics: Adenosine Diphosphate; Aspirin; Atorvastatin; Calcium Channel Blockers; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP3A; Drug Substitution; Drug Therapy, Combination; Female; Fluorobenzenes; Genotype; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Pravastatin; Prospective Studies; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Sulfonamides; Ticlopidine | 2012 |
Clinical features and racial/ethnic differences among the 3020 participants in the Secondary Prevention of Small Subcortical Strokes (SPS3) trial.
Topics: Aged; Antihypertensive Agents; Aspirin; Black or African American; Blood Pressure; Chi-Square Distribution; Clopidogrel; Diabetes Mellitus; Drug Administration Schedule; Drug Therapy, Combination; Ethnicity; Female; Hispanic or Latino; Humans; Hypertension; Magnetic Resonance Imaging; Male; Middle Aged; North America; Platelet Aggregation Inhibitors; Prevalence; Racial Groups; Risk Factors; Secondary Prevention; Smoking; South America; Spain; Stroke; Ticlopidine; Time Factors; Treatment Outcome; White People | 2013 |
Risk of intracerebral hemorrhage in patients with cerebral microbleeds undergoing endovascular intervention.
Topics: Aged; Aged, 80 and over; Aspirin; Atherosclerosis; Brain Ischemia; Cerebral Hemorrhage; Clopidogrel; Endovascular Procedures; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Stroke; Ticlopidine | 2012 |
Thrombelastographic haemostatic status and antiplatelet therapy after coronary artery bypass surgery (TEG-CABG trial): assessing and monitoring the antithrombotic effect of clopidogrel and aspirin versus aspirin alone in hypercoagulable patients: study pr
Topics: Aspirin; Clinical Protocols; Clopidogrel; Coronary Artery Bypass; Humans; Platelet Aggregation Inhibitors; Prospective Studies; Thrombelastography; Thromboembolism; Thrombophilia; Ticlopidine | 2012 |
Ability of rabeprazole to prevent gastric mucosal damage from clopidogrel and low doses of aspirin depends on CYP2C19 genotype.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Aryl Hydrocarbon Hydroxylases; Asian People; Aspirin; Clopidogrel; Cross-Over Studies; Cytochrome P-450 CYP2C19; Endoscopy, Gastrointestinal; Female; Gastric Mucosa; Genotype; Humans; Male; Peptic Ulcer; Rabeprazole; Severity of Illness Index; Ticlopidine; Treatment Outcome; Young Adult | 2012 |
Combination therapy with warfarin plus clopidogrel improves outcomes in femoropopliteal bypass surgery patients.
Topics: Administration, Oral; Aged; Aspirin; Cardiovascular Diseases; Chi-Square Distribution; Clopidogrel; Comorbidity; Drug Therapy, Combination; Female; Femoral Artery; Graft Occlusion, Vascular; Humans; Logistic Models; Male; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Popliteal Artery; Proportional Hazards Models; Prospective Studies; Ticlopidine; Treatment Outcome; Vascular Patency; Warfarin | 2012 |
Impact of clopidogrel and aspirin treatment on the expression of proteins in platelets from type-2 diabetic patients with stable coronary ischemia.
Topics: Aged; Amino Acid Sequence; Aspirin; Blood Platelets; Clopidogrel; Coronary Disease; Cytoskeletal Proteins; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Gene Expression Regulation; Humans; Male; Molecular Sequence Data; Platelet Aggregation Inhibitors; Platelet Factor 4; Proteome; Ticlopidine | 2012 |
Polyunsaturated omega-3 fatty acids improve responsiveness to clopidogrel after percutaneous coronary intervention in patients with cytochrome P450 2C19 loss-of-function polymorphism.
Topics: Administration, Cutaneous; Aged; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Double-Blind Method; Drug Synergism; Fatty Acids, Omega-3; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Prospective Studies; Ticlopidine | 2012 |
Impact of high post-loading platelet aggregation on 30-day clinical outcomes after primary percutaneous coronary intervention. The antiplatelet regimen tailoring after primary PCI (ART-PCI) trial.
Topics: Aged; Aspirin; Clopidogrel; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Postoperative Complications; Single-Blind Method; Ticlopidine; Time Factors; Treatment Outcome | 2013 |
Mortality benefit with prasugrel in the TRITON-TIMI 38 coronary artery bypass grafting cohort: risk-adjusted retrospective data analysis.
Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Aspirin; Blood Loss, Surgical; Cause of Death; Chest Tubes; Clopidogrel; Cohort Studies; Combined Modality Therapy; Coronary Artery Bypass; Drug Administration Schedule; Drug Therapy, Combination; Erythrocyte Transfusion; Female; Follow-Up Studies; Hemorrhage; Humans; Male; Middle Aged; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Recurrence; Retrospective Studies; Risk Adjustment; Thiophenes; Ticlopidine | 2012 |
Clopidogrel plus indobufen in acute coronary syndrome patients with hypersensitivity to aspirin undergoing percutaneous coronary intervention.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Drug Hypersensitivity; Drug Therapy, Combination; Female; Humans; Isoindoles; Male; Middle Aged; Percutaneous Coronary Intervention; Phenylbutyrates; Platelet Aggregation Inhibitors; Risk Factors; Thromboxane B2; Ticlopidine; Treatment Outcome | 2013 |
Effects of pantoprazole on dual antiplatelet therapy in stable angina pectoris patients after percutaneous coronary intervention.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Angina, Stable; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Thrombosis; Drug Interactions; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Pantoprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Proton Pump Inhibitors; Stents; Ticlopidine; Treatment Outcome | 2012 |
Effect of a multifaceted intervention on use of evidence-based therapies in patients with acute coronary syndromes in Brazil: the BRIDGE-ACS randomized trial.
Topics: Acute Coronary Syndrome; Aged; Anticoagulants; Aspirin; Brazil; Case Management; Checklist; Clopidogrel; Developing Countries; Education, Medical, Continuing; Evidence-Based Practice; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Platelet Aggregation Inhibitors; Quality Improvement; Reminder Systems; Single-Blind Method; Ticlopidine; Urban Population | 2012 |
Effects of cilostazol on cognition and regional cerebral blood flow in patients with Alzheimer's disease and cerebrovascular disease: a pilot study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Aspirin; Cerebrovascular Circulation; Cerebrovascular Disorders; Cilostazol; Clopidogrel; Cognition; Female; Humans; Magnetic Resonance Imaging; Male; Neuroprotective Agents; Platelet Aggregation Inhibitors; Prospective Studies; Statistics, Nonparametric; Tetrazoles; Ticlopidine; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; Treatment Outcome | 2013 |
Clopidogrel trial in patients with elective percutaneous coronary intervention for stable angina and old myocardial infarction (CLEAN).
Topics: Adult; Aged; Angina, Stable; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Combined Modality Therapy; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Hemorrhage; Humans; Incidence; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk Assessment; Ticlopidine; Treatment Outcome; Young Adult | 2012 |
Recovery of platelet function after discontinuation of prasugrel or clopidogrel maintenance dosing in aspirin-treated patients with stable coronary disease: the recovery trial.
Topics: Adult; Aged; Aspirin; Blood Loss, Surgical; Blood Platelets; Clopidogrel; Confounding Factors, Epidemiologic; Coronary Disease; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Piperazines; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Prasugrel Hydrochloride; Thiophenes; Ticlopidine | 2012 |
P2Y12 platelet reactivity after thrombolytic therapy for ST-segment elevation myocardial infarction.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Activation; Platelet Aggregation Inhibitors; Receptors, Purinergic P2Y12; Thrombolytic Therapy; Ticlopidine; Treatment Outcome | 2012 |
Effects of pioglitazone on platelet P2Y12-mediated signalling in clopidogrel-treated patients with type 2 diabetes mellitus.
Topics: Aged; Aspirin; Clopidogrel; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Interactions; Female; Humans; Hypoglycemic Agents; Male; Middle Aged; Pioglitazone; Platelet Aggregation; Prospective Studies; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Signal Transduction; Thiazolidinediones; Ticlopidine | 2012 |
Triple vs. dual antiplatelet therapy in patients with acute myocardial infarction and renal dysfunction.
Topics: Aged; Aged, 80 and over; Aspirin; Cilostazol; Clopidogrel; Disease-Free Survival; Drug Therapy, Combination; Female; Humans; Kidney Diseases; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Survival Rate; Tetrazoles; Ticlopidine | 2012 |
Relation between clopidogrel active metabolite levels and different platelet aggregation methods in patients receiving clopidogrel and aspirin.
Topics: Adenosine Diphosphate; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prodrugs; Ticlopidine; Time Factors | 2012 |
Angioplasty and stent treatment of transplant renal artery stenosis.
Topics: Adult; Aged; Angioplasty; Anticoagulants; Aspirin; Clopidogrel; Female; Follow-Up Studies; Humans; Hypertension, Renovascular; Kidney Transplantation; Male; Middle Aged; Postoperative Complications; Prospective Studies; Renal Artery Obstruction; Risk Factors; Stents; Ticlopidine; Treatment Outcome; Ultrasonography | 2012 |
The impact of CYP3A5*1/*3, PIA1/A2 and T744C polymorphisms on clopidogrel and acetylsalicylic acid response variability in Mexican population.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Comorbidity; Cytochrome P-450 CYP3A; Drug Resistance; Female; Genetic Predisposition to Disease; Genetic Variation; Humans; Male; Mexico; Middle Aged; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Polymorphism, Single Nucleotide; Prevalence; Receptors, Purinergic P2Y12; Risk Factors; Thrombosis; Ticlopidine; Treatment Outcome | 2012 |
Perioperative assessment of platelet function by Thromboelastograph Platelet Mapping in cardiovascular patients undergoing non-cardiac surgery.
Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Perioperative Care; Platelet Aggregation Inhibitors; Platelet Function Tests; Thrombelastography; Ticlopidine | 2013 |
Influence of omeprazole and famotidine on the antiplatelet effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes: a prospective, randomized, multicenter study.
Topics: Acute Coronary Syndrome; Aged; Anti-Ulcer Agents; Aspirin; Blood Platelets; Clopidogrel; Drug Antagonism; Famotidine; Female; Humans; Male; Middle Aged; Myocardial Infarction; Omeprazole; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2012 |
The effectiveness of dual antiplatelet treatment in acute ischemic stroke patients with intracranial arterial stenosis: a subgroup analysis of CLAIR study.
Topics: Aspirin; Cerebrovascular Disorders; Clopidogrel; Constriction, Pathologic; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Ultrasonography, Doppler, Transcranial | 2013 |
Dual antiplatelet therapy in patients with aspirin resistance following coronary artery bypass grafting: study protocol for a randomized controlled trial [NCT01159639].
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Bypass; Croatia; Drug Resistance; Drug Therapy, Combination; Hemorrhage; Humans; Patient Readmission; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Research Design; Ticlopidine; Time Factors; Treatment Outcome | 2012 |
Prasugrel versus clopidogrel for acute coronary syndromes without revascularization.
Topics: Acute Coronary Syndrome; Aged; Angina, Unstable; Aspirin; Cardiovascular Diseases; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Stroke; Thiophenes; Ticlopidine | 2012 |
Effects of clopidogrel added to aspirin in patients with recent lacunar stroke.
Topics: Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Recurrence; Stroke; Stroke, Lacunar; Ticlopidine | 2012 |
Aspirin plus clopidogrel for optimal platelet inhibition following off-pump coronary artery bypass surgery: results from the CRYSSA (prevention of Coronary arteRY bypaSS occlusion After off-pump procedures) randomised study.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Bypass, Off-Pump; Coronary Occlusion; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine; Treatment Outcome | 2012 |
Tranexamic Acid in on-pump coronary artery bypass grafting without clopidogrel and aspirin cessation: randomized trial and 1-year follow-up.
Topics: Antifibrinolytic Agents; Aspirin; Blood Loss, Surgical; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine; Time Factors; Tranexamic Acid; Treatment Outcome | 2013 |
High on-treatment platelet reactivity on commonly prescribed antiplatelet agents following transient ischaemic attack or ischaemic stroke: results from the Trinity Antiplatelet Responsiveness (TRAP) study.
Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Cross-Over Studies; Female; Humans; Ischemic Attack, Transient; Leukocytes; Male; Middle Aged; P-Selectin; Pilot Projects; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Stroke; Tetraspanin 30; Ticlopidine | 2013 |
Thrombus and antiplatelet therapy in type 2 diabetes mellitus. A prospective study after non-ST elevation acute coronary syndrome and a randomised, blinded, placebo-controlled study in stable angina.
Topics: Acute Coronary Syndrome; Aged; Angina, Stable; Aspirin; Clopidogrel; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Thrombosis; Ticlopidine | 2012 |
The CHA2DS2-VASc score identifies those patients with atrial fibrillation and a CHADS2 score of 1 who are unlikely to benefit from oral anticoagulant therapy.
Topics: Administration, Oral; Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Brain Ischemia; Clopidogrel; Drug Therapy, Combination; Female; Fibrinolytic Agents; Humans; Kaplan-Meier Estimate; Male; Platelet Aggregation Inhibitors; Risk Assessment; Severity of Illness Index; Stroke; Thromboembolism; Ticlopidine | 2013 |
The influence of omeprazole on platelet inhibition of clopidogrel in various CYP2C19 mutant alleles.
Topics: Alleles; Aryl Hydrocarbon Hydroxylases; Aspirin; Blood Platelets; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Interactions; Humans; Male; Omeprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; Young Adult | 2012 |
Biological efficacy of twice daily aspirin in type 2 diabetic patients with coronary artery disease.
Topics: Analysis of Variance; Arachidonic Acid; Aspirin; Clopidogrel; Coronary Artery Disease; Cross-Over Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Drug Administration Schedule; Drug Resistance; Female; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine | 2012 |
Randomized comparison of new dual-antiplatelet therapy (aspirin, prasugrel) and triple-antiplatelet therapy (aspirin, clopidogrel, cilostazol) using P2Y12 point-of-care assay in patients with STEMI undergoing primary PCI.
Topics: Adult; Aged; Aspirin; Cilostazol; Clopidogrel; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Piperazines; Platelet Aggregation Inhibitors; Point-of-Care Systems; Prasugrel Hydrochloride; Prospective Studies; Receptors, Purinergic P2Y12; Tetrazoles; Thiophenes; Ticlopidine | 2013 |
Randomized controlled trial of symptomatic middle cerebral artery stenosis: endovascular versus medical therapy in a Chinese population.
Topics: Adult; Aged; Angioplasty; Asian People; Aspirin; Clopidogrel; Diabetes Mellitus; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hyperlipidemias; Hypertension; Infarction, Middle Cerebral Artery; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Risk Factors; Secondary Prevention; Stents; Ticlopidine; Treatment Outcome | 2012 |
Platelet function during extended prasugrel and clopidogrel therapy for patients with ACS treated without revascularization: the TRILOGY ACS platelet function substudy.
Topics: Acute Coronary Syndrome; Age Factors; Aged; Angina, Unstable; Aspirin; Body Weight; Clopidogrel; Female; Humans; Male; Myocardial Infarction; Myocardial Ischemia; Piperazines; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Stroke; Thiophenes; Ticlopidine; Treatment Outcome | 2012 |
Bedside monitoring to adjust antiplatelet therapy for coronary stenting.
Topics: Aged; Aspirin; Clopidogrel; Coronary Disease; Coronary Thrombosis; Drug Monitoring; Female; Humans; Male; Middle Aged; Myocardial Infarction; Piperazines; Platelet Aggregation Inhibitors; Point-of-Care Systems; Prasugrel Hydrochloride; Pyridines; Retreatment; Stents; Thiophenes; Ticlopidine | 2012 |
What is better antiplatelet agent to prevent recurrent stroke?
Topics: Angiotensin-Converting Enzyme Inhibitors; Aspirin; Benzimidazoles; Benzoates; Brain Ischemia; Clopidogrel; Dipyridamole; Double-Blind Method; Evidence-Based Medicine; Humans; Male; Middle Aged; Patient Compliance; Platelet Aggregation Inhibitors; Secondary Prevention; Stroke; Telmisartan; Ticlopidine; Treatment Outcome | 2012 |
Optimized duration of clopidogrel therapy following treatment with the Endeavor zotarolimus-eluting stent in real-world clinical practice (OPTIMIZE) trial: rationale and design of a large-scale, randomized, multicenter study.
Topics: Adult; Aspirin; Brazil; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Period; Prospective Studies; Research Design; Sirolimus; Ticlopidine; Time Factors; Treatment Outcome; Young Adult | 2012 |
Benefit of long-term dual anti-platelet therapy in patients treated with drug-eluting stents: from the NHLBI dynamic registry.
Topics: Antineoplastic Agents, Phytogenic; Aspirin; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug-Eluting Stents; Follow-Up Studies; Humans; Immunosuppressive Agents; Paclitaxel; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Recurrence; Registries; Retrospective Studies; Sirolimus; Survival Rate; Ticlopidine; Time Factors; Treatment Outcome; United States | 2013 |
Drug resistance and pseudoresistance: an unintended consequence of enteric coating aspirin.
Topics: Administration, Oral; Adolescent; Adult; Aspirin; Clopidogrel; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Resistance; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation Inhibitors; Stroke; Tablets, Enteric-Coated; Ticlopidine; Treatment Outcome; Young Adult | 2013 |
Increased platelet aggregation and turnover in the acute phase of ST-elevation myocardial infarction.
Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Cohort Studies; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Ticlopidine | 2013 |
Efficacy and safety of low-dose clopidogrel in Japanese patients after drug-eluting stent implantation: a randomized pilot trial.
Topics: Aged; Asian People; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Japan; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Pilot Projects; Platelet Aggregation Inhibitors; Prospective Studies; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome; Ultrasonography, Interventional | 2014 |
Increased local cytokine production at culprit superficial femoral artery plaques.
Topics: Aspirin; CD40 Ligand; Clopidogrel; Constriction, Pathologic; Female; Femoral Artery; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemia; Lower Extremity; Lymphotoxin-alpha; Male; Middle Aged; Plaque, Atherosclerotic; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine | 2013 |
Percutaneous left atrial appendage closure for stroke prophylaxis in patients with atrial fibrillation: 2.3-Year Follow-up of the PROTECT AF (Watchman Left Atrial Appendage System for Embolic Protection in Patients with Atrial Fibrillation) Trial.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Appendage; Atrial Fibrillation; Clopidogrel; Drug Therapy, Combination; Embolism; Female; Follow-Up Studies; Humans; Male; Prostheses and Implants; Stroke; Ticlopidine; Treatment Outcome; Warfarin | 2013 |
Clopidogrel added to aspirin adds no benefit but bleeding risk in patients with recent lacunar stroke.
Topics: Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Assessment; Risk Factors; Stroke, Lacunar; Ticlopidine | 2013 |
Spaced administration of PA32540 and clopidogrel results in greater platelet inhibition than synchronous administration of enteric-coated aspirin and enteric-coated omeprazole and clopidogrel.
Topics: Administration, Oral; Adult; Aspirin; Clopidogrel; Coronary Thrombosis; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Enzyme Inhibitors; Follow-Up Studies; Gastrointestinal Diseases; Humans; Middle Aged; Omeprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Tablets, Enteric-Coated; Ticlopidine; Treatment Outcome | 2013 |
Efficacy and safety of triple antiplatelet therapy in obese patients undergoing stent implantation.
Topics: Adult; Aged; Aspirin; Blood Platelets; Cilostazol; Clopidogrel; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Obesity; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prosthesis Implantation; Stents; Tetrazoles; Thrombosis; Ticlopidine; Treatment Outcome | 2013 |
Rationale and design of the on-treatment PLAtelet Reactivity-Guided Therapy Modification FOR ST-Segment Elevation Myocardial Infarction (PLATFORM) randomized trial.
Topics: Adenosine; Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Ticagrelor; Ticlopidine; Treatment Outcome | 2013 |
Use of clopidogrel with or without aspirin in patients taking oral anticoagulant therapy and undergoing percutaneous coronary intervention: an open-label, randomised, controlled trial.
Topics: Administration, Oral; Aged; Anticoagulants; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Hemorrhage; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticlopidine | 2013 |
Efficacy and safety of 12 versus 48 months of dual antiplatelet therapy after implantation of a drug-eluting stent: the OPTImal DUAL antiplatelet therapy (OPTIDUAL) trial: study protocol for a randomized controlled trial.
Topics: Aspirin; Clinical Protocols; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; France; Hemorrhage; Humans; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prosthesis Design; Research Design; Stroke; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2013 |
Telephone contact to improve adherence to dual antiplatelet therapy after drug-eluting stent implantation.
Topics: Aged; Aspirin; Clopidogrel; Coronary Thrombosis; Counseling; Drug Prescriptions; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Linear Models; Male; Medication Adherence; Middle Aged; Multivariate Analysis; Patient Discharge; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Quebec; Self Report; Telephone; Tertiary Care Centers; Ticlopidine; Time Factors; Treatment Outcome | 2013 |
Addition of cilostazol to conventional dual antiplatelet therapy reduces the risk of cardiac events and restenosis after drug-eluting stent implantation: a meta-analysis.
Topics: Aspirin; Cilostazol; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Female; Heart Diseases; Humans; Male; Middle Aged; Myocardial Revascularization; Odds Ratio; Platelet Aggregation Inhibitors; Risk; Tetrazoles; Ticlopidine | 2013 |
Dual antiplatelets reduce microembolic signals in patients with transient ischemic attack and minor stroke: subgroup analysis of CLAIR study.
Topics: Adult; Aged; Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Intracranial Embolism; Ischemic Attack, Transient; Male; Middle Aged; Molecular Sequence Data; Platelet Aggregation Inhibitors; Regression Analysis; Retrospective Studies; Severity of Illness Index; Stroke; Ticlopidine; Time Factors; Ultrasonography, Doppler, Transcranial | 2014 |
Anterior chamber bleeding after laser peripheral iridotomy.
Topics: Adult; Aged; Aged, 80 and over; Anterior Chamber; Anticoagulants; Aspirin; Clopidogrel; Eye Color; Female; Glaucoma, Angle-Closure; Gonioscopy; Humans; Hyphema; Incidence; Intraocular Pressure; Iridectomy; Iris; Laser Therapy; Lasers, Solid-State; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Prospective Studies; Risk Factors; Ticlopidine; Tonometry, Ocular; Warfarin | 2013 |
Relationship between postoperative clopidogrel use and subsequent angiographic and clinical outcomes following coronary artery bypass grafting.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Postoperative Care; Ticlopidine | 2013 |
The influence of smoking status on the pharmacokinetics and pharmacodynamics of clopidogrel and prasugrel: the PARADOX study.
Topics: Aged; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Coronary Artery Disease; Cross-Over Studies; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Piperazines; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Prospective Studies; Purinergic P2Y Receptor Antagonists; Smoking; Thiophenes; Ticlopidine | 2013 |
Long-term outcome of vincristine-aspirin-ticlopidine (VAT) therapy for vascular tumors associated with Kasabach-Merritt phenomenon.
Topics: Antineoplastic Combined Chemotherapy Protocols; Aspirin; Child, Preschool; Ecchymosis; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Infant; Infant, Newborn; Kasabach-Merritt Syndrome; Male; Platelet Aggregation Inhibitors; Platelet Count; Remission Induction; Retroperitoneal Neoplasms; Retrospective Studies; Ticlopidine; Vascular Neoplasms; Vincristine | 2013 |
Current medical management of stable coronary artery disease before and after elective percutaneous coronary intervention.
Topics: Adrenergic beta-Antagonists; Aged; Aspirin; Clopidogrel; Coloring Agents; Coronary Angiography; Coronary Artery Disease; Drug Therapy, Combination; Electrocardiography; Female; Follow-Up Studies; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Care; Preoperative Care; Retrospective Studies; Severity of Illness Index; Ticlopidine; Treatment Outcome | 2013 |
Platelet inhibitory effect of clopidogrel in patients treated with omeprazole, pantoprazole, and famotidine: a prospective, randomized, crossover study.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Aspirin; Chi-Square Distribution; Clopidogrel; Cross-Over Studies; Drug Interactions; Drug Resistance; Drug Therapy, Combination; Famotidine; Female; Histamine H2 Antagonists; Humans; Israel; Linear Models; Male; Middle Aged; Omeprazole; Pantoprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Proton Pump Inhibitors; Single-Blind Method; Ticlopidine; Time Factors; Treatment Outcome | 2013 |
[Prevention of non-acute stent thrombosis after drug-eluting stent implantation].
Topics: Aspirin; Clopidogrel; Drug-Eluting Stents; Female; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine; Tirofiban; Tyrosine; Warfarin | 2013 |
The effect of doubling the dose of acetylsalicylic acid (ASA) on platelet function parameters in patients with type 2 diabetes and platelet hyperreactivity during treatment with 75 mg of ASA: a subanalysis of the AVOCADO study.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Clopidogrel; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Platelet Function Tests; Prospective Studies; Ticlopidine | 2013 |
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
Topics: Aged; Aspirin; Clopidogrel; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; Female; Hemorrhage; Humans; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Proportional Hazards Models; Secondary Prevention; Stroke; Ticlopidine | 2013 |
Oral clopidogrel improves cutaneous microvascular function through EDHF-dependent mechanisms in middle-aged humans.
Topics: Administration, Oral; Analysis of Variance; Aspirin; Biological Factors; Blood Flow Velocity; Clopidogrel; Cross-Over Studies; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hyperemia; Laser-Doppler Flowmetry; Male; Microcirculation; Microdialysis; Microvessels; Middle Aged; Nitric Oxide; Nitric Oxide Donors; Pennsylvania; Purinergic P2Y Receptor Antagonists; Regional Blood Flow; Skin; Skin Temperature; Ticlopidine; Time Factors; Vasodilation | 2013 |
Discontinuation of antiplatelet study medication and risk of recurrent stroke and cardiovascular events: results from the PRoFESS study.
Topics: Aged; Aged, 80 and over; Aspirin; Aspirin, Dipyridamole Drug Combination; Clopidogrel; Dipyridamole; Drug Combinations; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk; Secondary Prevention; Stroke; Ticlopidine; Treatment Outcome | 2013 |
Elderly patients with acute coronary syndromes managed without revascularization: insights into the safety of long-term dual antiplatelet therapy with reduced-dose prasugrel versus standard-dose clopidogrel.
Topics: Acute Coronary Syndrome; Age Factors; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Disease Management; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Hemorrhage; Humans; Longitudinal Studies; Male; Middle Aged; Percutaneous Coronary Intervention; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Risk Factors; Thiophenes; Ticlopidine; Treatment Outcome | 2013 |
The pharmacokinetics and safety of a fixed-dose combination of acetylsalicylic acid and clopidogrel compared with the concurrent administration of acetylsalicylic acid and clopidogrel in healthy subjects: a randomized, open-label, 2-sequence, 2-period, si
Topics: Administration, Oral; Adult; Aspirin; Clopidogrel; Cross-Over Studies; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Healthy Volunteers; Humans; Male; Middle Aged; Ticlopidine; Young Adult | 2013 |
Platelet-oriented inhibition in new TIA and minor ischemic stroke (POINT) trial: rationale and design.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Research Design; Stroke; Ticlopidine; Young Adult | 2013 |
Platelet reactivity and clinical outcomes after coronary artery implantation of drug-eluting stents (ADAPT-DES): a prospective multicentre registry study.
Topics: Aspirin; Blood Coagulation Tests; Clopidogrel; Coronary Disease; Coronary Stenosis; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Point-of-Care Systems; Prospective Studies; Registries; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome | 2013 |
Short-term follow-up of tirofiban as alternative therapy for urgent surgery patients with an implanted coronary drug-eluting stent after ST-elevation myocardial infarction.
Topics: Aged; Aspirin; China; Clopidogrel; Drug Administration Schedule; Drug Substitution; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Prospective Studies; Risk Factors; Ticlopidine; Time Factors; Tirofiban; Treatment Outcome; Tyrosine | 2013 |
Pharmacodynamic effects of EV-077 in patients with diabetes mellitus and coronary artery disease on aspirin or clopidogrel monotherapy: results of an in vitro pilot investigation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus; Female; Humans; Male; Middle Aged; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Thromboxane; Ticlopidine | 2014 |
Aggressive medical therapy alone is not adequate in certain patients with severe symptomatic carotid stenosis.
Topics: Aspirin; Atorvastatin; Carotid Artery Diseases; Clopidogrel; Constriction, Pathologic; Endovascular Procedures; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Middle Aged; Platelet Aggregation Inhibitors; Pyrroles; Ticlopidine | 2013 |
Adjunctive cilostazol versus double-dose clopidogrel after drug-eluting stent implantation: the HOST-ASSURE randomized trial (Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis-Safety & Effectiveness of Drug-Eluting Stents & Anti-plate
Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prospective Studies; Prosthesis Design; Republic of Korea; Risk Factors; Stroke; Tetrazoles; Ticlopidine; Time Factors; Treatment Outcome | 2013 |
Primary thrombophilia in México X: a prospective study of the treatment of the sticky platelet syndrome.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Blood Platelet Disorders; Child; Clopidogrel; Female; Humans; Male; Mexico; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Syndrome; Thrombophilia; Thrombosis; Ticlopidine; Young Adult | 2015 |
Comparison of dual versus triple antiplatelet therapy after drug-eluting stent according to stent length (from the pooled analysis of DECLARE trials).
Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Diabetes Complications; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prosthesis Implantation; Tetrazoles; Ticlopidine; Treatment Outcome | 2013 |
Assessment of the risk of haemorrhage and its control following minor oral surgical procedures in patients on anti-platelet therapy: a prospective study.
Topics: Adult; Aged; Aspirin; Blood Loss, Surgical; Clopidogrel; Female; Hemostasis, Surgical; Humans; Male; Middle Aged; Oral Surgical Procedures; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Prospective Studies; Risk Factors; Ticlopidine | 2014 |
Paraoxonase-1 activity affects the clopidogrel response in CYP2C19 loss-of-function carriers.
Topics: Aged; Aryl Hydrocarbon Hydroxylases; Aryldialkylphosphatase; Aspirin; Clopidogrel; Cytochrome P-450 CYP2C19; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Thrombosis; Ticlopidine | 2013 |
Cost-effectiveness of ticagrelor and generic clopidogrel in patients with acute coronary syndrome in Switzerland.
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Clopidogrel; Cost-Benefit Analysis; Decision Support Techniques; Diagnostic Imaging; Double-Blind Method; Drug Costs; Drug Therapy, Combination; Drugs, Generic; Health Care Costs; Hospitalization; Humans; Markov Chains; Myocardial Reperfusion; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Quality-Adjusted Life Years; Switzerland; Ticagrelor; Ticlopidine | 2013 |
[Effectiveness and safety of tranexamic acid in patients receiving on-pump coronary artery bypass grafting without clopidogrel and aspirin cessation].
Topics: Aged; Aged, 80 and over; Aspirin; Blood Transfusion; Clopidogrel; Coronary Artery Bypass; Female; Humans; Male; Middle Aged; Postoperative Hemorrhage; Prospective Studies; Ticlopidine; Tranexamic Acid | 2013 |
Twelve-month results of a randomized trial comparing mono with dual antiplatelet therapy in endovascularly treated patients with peripheral artery disease.
Topics: Aged; Aged, 80 and over; Angioplasty, Balloon; Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Germany; Humans; Male; Middle Aged; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Prospective Studies; Recurrence; Stents; Ticlopidine; Time Factors; Treatment Outcome | 2013 |
Optimal duration of dual antiplatelet therapy after drug-eluting stent implantation: a randomized, controlled trial.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Combined Modality Therapy; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Female; Follow-Up Studies; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Risk Factors; Ticlopidine; Treatment Outcome | 2014 |
Ischaemic cardiac outcomes in patients with atrial fibrillation treated with vitamin K antagonism or factor Xa inhibition: results from the ROCKET AF trial.
Topics: Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Double-Blind Method; Embolism; Female; Humans; Kaplan-Meier Estimate; Male; Morpholines; Myocardial Infarction; Platelet Aggregation Inhibitors; Pyridines; Rivaroxaban; Stroke; Thiophenes; Ticlopidine; Treatment Outcome; Warfarin | 2014 |
Discharge aspirin dose and clinical outcomes in patients with acute coronary syndromes treated with prasugrel versus clopidogrel: an analysis from the TRITON-TIMI 38 study (trial to assess improvement in therapeutic outcomes by optimizing platelet inhibit
Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Patient Discharge; Percutaneous Coronary Intervention; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Thiophenes; Ticlopidine; Time Factors; Treatment Outcome | 2014 |
Pharmacokinetic and pharmacodynamic properties of batifiban coadministered with antithrombin agents in Chinese healthy volunteers.
Topics: Administration, Oral; Adolescent; Adult; Area Under Curve; Aspirin; China; Clopidogrel; Drug Administration Schedule; Female; Fibrinolytic Agents; Heparin; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Metabolic Clearance Rate; Peptides, Cyclic; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors; Young Adult | 2013 |
Pharmacodynamic effects of standard dose prasugrel versus high dose clopidogrel in non-diabetic obese patients with coronary artery disease.
Topics: Aspirin; Biomarkers; Blood Platelets; Body Mass Index; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Florida; Humans; Male; Microfilament Proteins; Middle Aged; Obesity; Phosphoproteins; Phosphorylation; Piperazines; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Prospective Studies; Receptors, Purinergic P2Y12; Thiophenes; Ticlopidine; Time Factors; Treatment Outcome | 2014 |
Short- versus long-term duration of dual antiplatelet therapy in patients treated for in-stent restenosis: a PRODIGY trial substudy (Prolonging Dual Antiplatelet Treatment After Grading Stent-Induced Intimal Hyperplasia).
Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Coronary Restenosis; Female; Humans; Italy; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Complications; Stroke; Ticlopidine | 2014 |
Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
Topics: Adult; Aged; Aged, 80 and over; Angioplasty; Aspirin; Carotid Stenosis; Clopidogrel; Female; Follow-Up Studies; Humans; Intracranial Arteriosclerosis; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Secondary Prevention; Single-Blind Method; Stents; Stroke; Ticlopidine; Treatment Outcome | 2014 |
Three vs twelve months of dual antiplatelet therapy after zotarolimus-eluting stents: the OPTIMIZE randomized trial.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk; Sirolimus; Stroke; Thrombosis; Ticlopidine | 2013 |
[Effect of aspirin plus clopidogrel therapy on aspirin resistance after off-pump coronary artery bypass surgery].
Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Bypass, Off-Pump; Coronary Disease; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Period; Ticlopidine | 2013 |
Decreased circulating microRNA-223 level predicts high on-treatment platelet reactivity in patients with troponin-negative non-ST elevation acute coronary syndrome.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Biomarkers; Blood Platelets; Clopidogrel; Cytochrome P-450 CYP2C19; Female; Humans; Male; MicroRNAs; Middle Aged; Platelet Aggregation Inhibitors; Real-Time Polymerase Chain Reaction; Retrospective Studies; Ticlopidine; Troponin | 2014 |
The effects of laropiprant on the antiplatelet activity of co-administered clopidogrel and aspirin.
Topics: Adult; Aged; Aspirin; Clopidogrel; Cross-Over Studies; Double-Blind Method; Drug Interactions; Dyslipidemias; Female; Humans; Hypercholesterolemia; Indoles; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine; Young Adult | 2014 |
Impact of smoking on long-term outcomes in patients with atherosclerotic vascular disease treated with aspirin or clopidogrel: insights from the CAPRIE trial (Clopidogrel Versus Aspirin in Patients at Risk of Ischemic Events).
Topics: Aspirin; Atherosclerosis; Brain Ischemia; Clopidogrel; Female; Humans; Male; Risk Factors; Single-Blind Method; Smoking; Ticlopidine; Time Factors; Treatment Outcome | 2014 |
A randomized phase II trial investigating the effect of platelet function inhibition on circulating tumor cells in patients with metastatic breast cancer.
Topics: Aspirin; Blood Platelets; Breast Neoplasms; Case-Control Studies; Clopidogrel; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Middle Aged; Neoplasm Metastasis; Neoplastic Cells, Circulating; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Prognosis; Ticlopidine; Treatment Outcome | 2013 |
Study of pharmacodynamic interaction of Phyllanthus emblica extract with clopidogrel and ecosprin in patients with type II diabetes mellitus.
Topics: Aged; Aspirin; Clopidogrel; Cross-Over Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Herb-Drug Interactions; Humans; Male; Middle Aged; Phyllanthus emblica; Phytotherapy; Plant Extracts; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine | 2014 |
ASA failure: does the combination ASA/clopidogrel confer better long-term vascular protection?
Topics: Aged; Aspirin; Clopidogrel; Cohort Studies; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neuroprotective Agents; Platelet Aggregation Inhibitors; Stroke, Lacunar; Ticlopidine; Time Factors; Treatment Failure | 2014 |
Pharmacodynamic comparison of pitavastatin versus atorvastatin on platelet reactivity in patients with coronary artery disease treated with dual antiplatelet therapy.
Topics: Aged; Aged, 80 and over; Aspirin; Atorvastatin; Clopidogrel; Coronary Artery Disease; Cross-Sectional Studies; Cytochrome P-450 CYP3A; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Platelet Aggregation Inhibitors; Pyrroles; Quinolines; Ticlopidine | 2014 |
[Effects of preoperative uses of aspirin and clopidogrel on patients undergoing coronary artery bypass graft surgery].
Topics: Aged; Aspirin; Blood Loss, Surgical; Clopidogrel; Coronary Artery Bypass, Off-Pump; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Preoperative Care; Prognosis; Ticlopidine | 2013 |
Detecting a thienopyridine effect by platelet reactivity assessment and its implications for risk stratification.
Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Piperazines; Platelet Activation; Point-of-Care Systems; Prasugrel Hydrochloride; Pyridines; Receptors, Purinergic P2Y12; Reproducibility of Results; ROC Curve; Sensitivity and Specificity; Thiophenes; Ticlopidine; Time Factors; Treatment Outcome | 2014 |
Clinical implications and correlates of Q waves in patients with ST-elevation myocardial infarction treated with fibrinolysis: observations from the CLARITY-TIMI 28 trial.
Topics: Aged; Aspirin; Clopidogrel; Coronary Angiography; Coronary Circulation; Coronary Thrombosis; Creatine Kinase, MB Form; Electrocardiography; Female; Heart Failure; Hospitalization; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Reperfusion; Platelet Aggregation Inhibitors; Prognosis; Risk Assessment; Sex Factors; Ticlopidine | 2014 |
Von Willebrand factor antigen predicts response to double dose of aspirin and clopidogrel by PFA-100 in patients undergoing primary angioplasty for ST elevation myocardial infarction.
Topics: ADAM Proteins; ADAMTS13 Protein; Aged; Aspirin; Clopidogrel; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Revascularization; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Retrospective Studies; Ticlopidine; von Willebrand Factor | 2013 |
N-3 polyunsaturated fatty acids do not influence the efficacy of dual antiplatelet therapy in stable angina pectoris patients after percutaneous coronary intervention.
Topics: Aged; Angina, Stable; Aspirin; Blood Platelets; Clopidogrel; Docosahexaenoic Acids; Drug Combinations; Drug Therapy, Combination; Eicosapentaenoic Acid; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Poland; Prospective Studies; Ticlopidine; Time Factors; Treatment Outcome | 2013 |
Effect of ASA dose doubling versus switching to clopidogrel on plasma inflammatory markers concentration in patients with type 2 diabetes and high platelet reactivity: the AVOCADO study.
Topics: Aspirin; Biomarkers; Blood Platelets; C-Reactive Protein; CD40 Ligand; Chi-Square Distribution; Clopidogrel; Diabetes Mellitus, Type 2; Drug Substitution; Humans; Inflammation Mediators; Interleukin-6; Logistic Models; Multivariate Analysis; Odds Ratio; Platelet Aggregation Inhibitors; Platelet Function Tests; Poland; Prospective Studies; Ticlopidine; Time Factors; Treatment Outcome; Tumor Necrosis Factor-alpha | 2013 |
A comparative evaluation of prasugrel and clopidogrel in patients with acute coronary syndrome undergoing percutaneous coronary intervention.
Topics: Acute Coronary Syndrome; Adult; Aged; Aspirin; Clopidogrel; Combined Modality Therapy; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Thiophenes; Ticlopidine; Treatment Outcome | 2013 |
One-year outcome of patients with atrial fibrillation undergoing coronary artery stenting: an analysis of the AFCAS registry.
Topics: Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Vessels; Female; Fibrinolytic Agents; Humans; Male; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prospective Studies; Registries; Stents; Ticlopidine; Vitamin K | 2014 |
C-reactive protein as a prognostic marker after lacunar stroke: levels of inflammatory markers in the treatment of stroke study.
Topics: Aged; Antihypertensive Agents; Aspirin; Biomarkers; Blood Pressure; C-Reactive Protein; Clopidogrel; Cohort Studies; Confidence Intervals; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation Mediators; Male; Middle Aged; Phlebotomy; Platelet Aggregation Inhibitors; Proportional Hazards Models; Prospective Studies; Recurrence; Sample Size; Stroke, Lacunar; Ticlopidine; Treatment Outcome | 2014 |
Effect of clopidogrel with or without omeprazole in patients with carotid artery stenting.
Topics: Angiography; Aspirin; Breath Tests; Carotid Arteries; Carotid Stenosis; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Omeprazole; Peptic Ulcer; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Stents; Ticlopidine | 2013 |
Aspirin decreases systemic exposure to clopidogrel through modulation of P-glycoprotein but does not alter its antithrombotic activity.
Topics: Adenosine Diphosphate; Adult; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Aryldialkylphosphatase; Aspirin; ATP Binding Cassette Transporter, Subfamily B, Member 1; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Interactions; Fibrinolytic Agents; Genotype; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; RNA, Messenger; Ticlopidine | 2014 |
[The effect of clopidogrel and aspigrel on myocardial ischemia in patients with unstable angina pectoris].
Topics: Aged; Angina, Unstable; Aspirin; Clopidogrel; Drug Combinations; Drug Therapy, Combination; Humans; Middle Aged; Myocardial Ischemia; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2013 |
Prevention of gastric mucosal injury induced by anti-platelet drugs by famotidine.
Topics: Adult; Anti-Ulcer Agents; Asian People; Aspirin; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Famotidine; Female; Gastric Acidity Determination; Gastric Mucosa; Genotype; Helicobacter Infections; Helicobacter pylori; Histamine H2 Antagonists; Humans; Hydrogen-Ion Concentration; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; Young Adult | 2014 |
Modifying effect of dual antiplatelet therapy on incidence of stent thrombosis according to implanted drug-eluting stent type.
Topics: Aspirin; Blood Vessel Prosthesis; Clopidogrel; Coronary Restenosis; Coronary Thrombosis; Drug-Eluting Stents; Female; Fibrinolytic Agents; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Prosthesis Failure; Sirolimus; Ticlopidine; Treatment Outcome | 2014 |
A randomized, double-blind, placebo-controlled study of rebamipide for gastric mucosal injury taking aspirin with or without clopidogrel.
Topics: Adult; Alanine; Anti-Ulcer Agents; Aspirin; Clopidogrel; Double-Blind Method; Gastric Mucosa; Gastrointestinal Hemorrhage; Healthy Volunteers; Humans; Male; Peptic Ulcer; Platelet Aggregation Inhibitors; Quinolones; Ticlopidine; Young Adult | 2014 |
Inhibition of platelet activation could decrease thrombotic events in hemodialysis PF4/H antibody-positive patients.
Topics: Adult; Aged; Aspirin; Clopidogrel; Female; Humans; Incidence; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Factor 4; Renal Dialysis; Thrombosis; Ticlopidine | 2014 |
Impact of dual antiplatelet therapy on outcomes among aspirin-resistant patients following coronary artery bypass grafting.
Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Croatia; Dose-Response Relationship, Drug; Drug Resistance; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Incidence; Male; Platelet Aggregation Inhibitors; Postoperative Care; Postoperative Complications; Retrospective Studies; Survival Rate; Ticlopidine; Treatment Outcome | 2014 |
Effect of esomeprazole with/without acetylsalicylic acid, omeprazole and lansoprazole on pharmacokinetics and pharmacodynamics of clopidogrel in healthy volunteers.
Topics: Adolescent; Adult; Area Under Curve; Aspirin; Clopidogrel; Cross-Over Studies; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Esomeprazole; Female; Healthy Volunteers; Humans; Lansoprazole; Male; Middle Aged; Omeprazole; Platelet Aggregation; Proton Pump Inhibitors; Ticlopidine; Young Adult | 2014 |
Clopidogrel plus aspirin versus warfarin in patients with stroke and aortic arch plaques.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aorta, Thoracic; Aortic Diseases; Aspirin; Brain Ischemia; Clopidogrel; Drug Therapy, Combination; Embolism; Female; Humans; Male; Middle Aged; Plaque, Atherosclerotic; Platelet Aggregation Inhibitors; Prospective Studies; Single-Blind Method; Stroke; Ticlopidine; Treatment Outcome; Warfarin | 2014 |
Pharmacodynamic efficacy and safety of adjunctive cilostazol loading to clopidogrel and aspirin loading: the results of the ACCEL-LOADING (Accelerated Platelet Inhibition by Cilostazol Loading) study.
Topics: Aspirin; Cilostazol; Clopidogrel; Cross-Over Studies; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Prospective Studies; Tetrazoles; Ticlopidine | 2014 |
A comparative study of dual versus monoantiplatelet therapy in patients with acute large-artery atherosclerosis stroke.
Topics: Aged; Aspirin; Clopidogrel; Drug Therapy, Combination; Endpoint Determination; Female; Humans; Intracranial Arteriosclerosis; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Recurrence; Stroke; Ticlopidine | 2014 |
Prospective validation of the Bleeding Academic Research Consortium classification in the all-comer PRODIGY trial.
Topics: Administration, Oral; Aged; Aspirin; Clopidogrel; Epidemiologic Methods; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Recurrence; Ticlopidine | 2014 |
Efficacy and safety of adjusted-dose prasugrel compared with clopidogrel in Japanese patients with acute coronary syndrome: the PRASFIT-ACS study.
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Asian People; Aspirin; Clopidogrel; Drug Therapy, Combination; Follow-Up Studies; Hemorrhage; Humans; Japan; Middle Aged; Myocardial Infarction; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Thiophenes; Ticlopidine; Time Factors | 2014 |
Effects of simvastatin/ezetimibe on microparticles, endothelial progenitor cells and platelet aggregation in subjects with coronary heart disease under antiplatelet therapy.
Topics: Aged; Anticholesteremic Agents; Aspirin; Azetidines; Cell-Derived Microparticles; Cholesterol, LDL; Clopidogrel; Coronary Disease; Drug Combinations; Endothelial Progenitor Cells; Ezetimibe; Female; Flow Cytometry; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Simvastatin; Ticlopidine; Triglycerides | 2014 |
Impact of CYP3A5 polymorphism on platelet reactivity at percutaneous coronary intervention and after 9 months of aspirin and clopidogrel therapy in Japanese patients with coronary artery disease.
Topics: Asian People; Aspirin; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Drug Therapy, Combination; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Activation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Ticlopidine; Time Factors | 2014 |
A prospective randomised study of the paclitaxel-coated balloon catheter in bifurcated coronary lesions (BABILON trial): 24-month clinical and angiographic results.
Topics: Aged; Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Restenosis; Coronary Stenosis; Drug-Eluting Stents; Everolimus; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; Paclitaxel; Platelet Aggregation Inhibitors; Sirolimus; Stents; Ticlopidine; Treatment Outcome; Tubulin Modulators | 2014 |
Pharmacodynamics, pharmacokinetics and safety of ticagrelor in Asian patients with stable coronary artery disease.
Topics: Adenosine; Adult; Aged; Aged, 80 and over; Asian People; Aspirin; Clopidogrel; Coronary Artery Disease; Double-Blind Method; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Function Tests; Purinergic P2Y Receptor Antagonists; Ticagrelor; Ticlopidine; Young Adult | 2014 |
Platelet reactivity and cardiovascular events after percutaneous coronary intervention in patients with stable coronary artery disease: the Stent Thrombosis In Belgium (STIB) trial.
Topics: Aged; Angina, Stable; Aspirin; Belgium; Blood Platelets; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Female; Hemorrhage; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Odds Ratio; Percutaneous Coronary Intervention; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prospective Studies; Risk Factors; Stents; Stroke; Ticlopidine; Time Factors; Treatment Outcome | 2014 |
Monitoring the efficacy of ADP inhibitor treatment in patients with acute STEMI post-PCI by VASP-P flow cytometry assay.
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Female; Flow Cytometry; Follow-Up Studies; Humans; Male; Microfilament Proteins; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Phosphoproteins; Platelet Activation; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine | 2015 |
Prasugrel but not high dose clopidogrel overcomes the lansoprazole neutralizing effect of P2Y12 inhibition: Results of the randomized DOSAPI study.
Topics: Adult; Aged; Anti-Ulcer Agents; Aspirin; Clopidogrel; Coronary Artery Disease; Double-Blind Method; Drug Interactions; Female; Humans; Lansoprazole; Male; Middle Aged; Piperazines; Platelet Activation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Thiophenes; Ticlopidine | 2014 |
An analysis of TRITON-TIMI 38, based on the 12 month recommended length of therapy in the European label for prasugrel.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Cohort Studies; Coronary Artery Bypass; Drug Administration Schedule; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Risk Assessment; Stents; Stroke; Thiophenes; Ticlopidine | 2014 |
Impact of aspirin resistance on outcomes among patients following coronary artery bypass grafting: exploratory analysis from randomized controlled trial (NCT01159639).
Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Bypass; Drug Resistance; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Care; Ticlopidine | 2015 |
Ticagrelor reduces thrombus formation more than clopidogrel, even when co-administered with bivalirudin.
Topics: Adenosine; Adult; Antithrombins; Aspirin; Blood Coagulation; Clopidogrel; Cross-Over Studies; Drug Synergism; Female; Healthy Volunteers; Hirudins; Humans; Male; Peptide Fragments; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Recombinant Proteins; Thrombelastography; Ticagrelor; Ticlopidine | 2014 |
Influence of carotid artery stenting on cognition of elderly patients with severe stenosis of the internal carotid artery.
Topics: Aged; Analysis of Variance; Angioplasty; Aspirin; Atorvastatin; Carotid Stenosis; China; Clopidogrel; Cognition; Female; Heptanoic Acids; Humans; Male; Pyrroles; Quality of Life; Regional Blood Flow; Stents; Ticlopidine; Treatment Outcome; Ultrasonography, Doppler, Transcranial | 2014 |
Predictors of mortality in patients with lacunar stroke in the secondary prevention of small subcortical strokes trial.
Topics: Aged; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Proportional Hazards Models; Secondary Prevention; Stroke, Lacunar; Ticlopidine | 2014 |
Effect of adjunctive dipyridamole to DAPT on platelet function profiles in stented patients with high platelet reactivity. The result of the ACCEL-DIP Study.
Topics: Aged; Aspirin; ATP Binding Cassette Transporter, Subfamily B; Biomarkers; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Dipyridamole; Drug Resistance; Drug Therapy, Combination; Female; Genotype; Humans; Male; Microfilament Proteins; Middle Aged; Percutaneous Coronary Intervention; Phosphodiesterase 5 Inhibitors; Phosphoproteins; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Republic of Korea; Stents; Ticlopidine; Time Factors; Treatment Outcome | 2014 |
Initial 3-weeks' Apixaban Versus Dual-antiplatelet Therapy (Clopidogrel and Aspirin) followed by Clopidogrel alone in high-risk patients with Acute Non-Disabling Cerebrovascular Events (ADANCE): study protocol for a randomized controlled trial.
Topics: Administration, Oral; Adolescent; Adult; Aspirin; Clopidogrel; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Endpoint Determination; Female; Humans; Male; Platelet Aggregation Inhibitors; Pyrazoles; Pyridones; Stroke; Ticlopidine; Time Factors; Treatment Outcome; Young Adult | 2014 |
Efficacy of two different self-expanding nitinol stents for atherosclerotic femoropopliteal arterial disease (SENS-FP trial): study protocol for a randomized controlled trial.
Topics: Alloys; Angioplasty, Balloon; Aspirin; Cilostazol; Clinical Protocols; Clopidogrel; Drug Therapy, Combination; Femoral Artery; Humans; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Popliteal Artery; Prospective Studies; Prosthesis Design; Prosthesis Failure; Research Design; Stents; Tetrazoles; Ticlopidine; Time Factors; Treatment Outcome; Vascular Patency | 2014 |
Clopidogrel plus aspirin versus aspirin alone for preventing early neurological deterioration in patients with acute ischemic stroke.
Topics: Aged; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Stroke; Ticlopidine; Treatment Outcome; United States | 2015 |
Switching from generic to brand clopidogrel in male patients after ST-elevated myocardial infarction.
Topics: Adenosine Diphosphate; Aspirin; Clopidogrel; Drug Substitution; Drug Therapy, Combination; Drugs, Generic; Epinephrine; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine | 2014 |
Clopidogrel plus aspirin prevents early neurologic deterioration and improves 6-month outcome in patients with acute large artery atherosclerosis stroke.
Topics: Acute Disease; Aged; Aspirin; Atherosclerosis; Clopidogrel; Female; Humans; Male; Nervous System Diseases; Platelet Aggregation; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Treatment Outcome | 2015 |
Twelve or 30 months of dual antiplatelet therapy after drug-eluting stents.
Topics: Aged; Aspirin; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Humans; Incidence; Male; Middle Aged; Myocardial Ischemia; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Thrombosis; Ticlopidine; Time Factors | 2014 |
Tradeoff between bleeding and stent thrombosis in different dual antiplatelet therapy regimes: Importance of case fatality rates and effective treatment durations.
Topics: Aged; Angina Pectoris; Aspirin; Clopidogrel; Coronary Thrombosis; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Humans; Maintenance Chemotherapy; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prosthesis Failure; Risk Assessment; Sirolimus; Ticlopidine; Time Factors; Treatment Outcome | 2014 |
Effects of long-term blood pressure lowering and dual antiplatelet treatment on cognitive function in patients with recent lacunar stroke: a secondary analysis from the SPS3 randomised trial.
Topics: Aged; Aspirin; Blood Pressure; Clopidogrel; Cognition; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Stroke, Lacunar; Ticlopidine; Time Factors; Treatment Outcome | 2014 |
6- versus 24-month dual antiplatelet therapy after implantation of drug-eluting stents in patients nonresistant to aspirin: the randomized, multicenter ITALIC trial.
Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Coronary Vessels; Drug-Eluting Stents; Early Termination of Clinical Trials; Europe; Everolimus; Female; Hemorrhage; Humans; Immunosuppressive Agents; Male; Middle Aged; Middle East; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Complications; Sirolimus; Ticlopidine; Time Factors; Treatment Outcome | 2015 |
Is clopidogrel better than aspirin following breakthrough strokes while on aspirin? A retrospective cohort study.
Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Hospitalization; Humans; Incidence; Male; Platelet Aggregation Inhibitors; Recurrence; Retrospective Studies; Survival Rate; Taiwan; Ticlopidine; Treatment Outcome | 2014 |
Does rectal indomethacin given for prevention of post-ERCP pancreatitis increase bleeding after biliary endoscopic sphincterotomy or cardiovascular mortality?: Post hoc analysis using prospective clinical trial data.
Topics: Administration, Rectal; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Cholangiopancreatography, Endoscopic Retrograde; Clopidogrel; Double-Blind Method; Female; Humans; Indomethacin; Male; Middle Aged; Pancreatitis; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Sphincterotomy, Endoscopic; Ticlopidine | 2014 |
Protocol for Cilostazol Stroke Prevention Study for Antiplatelet Combination (CSPS.com): a randomized, open-label, parallel-group trial.
Topics: Aged; Aspirin; Brain Ischemia; Cilostazol; Clopidogrel; Drug Therapy, Combination; Humans; Phosphodiesterase 3 Inhibitors; Platelet Aggregation Inhibitors; Recurrence; Research Design; Stroke; Tetrazoles; Ticlopidine | 2015 |
Rationale and design of MANJUSRI trial: a randomized, open-label, active-controlled multicenter study to evaluate the safety of combined therapy with ticagrelor and warfarin in AF subjects after PCI-eS.
Topics: Adenosine; Adolescent; Adult; Aged; Aspirin; Atrial Fibrillation; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Female; Fibrinolytic Agents; Hemorrhage; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Prospective Studies; Research Design; Ticagrelor; Ticlopidine; Warfarin; Young Adult | 2015 |
Incidence, predictors, and prognostic impact of late bleeding complications after transcatheter aortic valve replacement.
Topics: Aged; Aged, 80 and over; Aortic Valve Stenosis; Aspirin; Clopidogrel; Echocardiography; Female; Follow-Up Studies; Hemorrhage; Humans; Incidence; Kaplan-Meier Estimate; Male; Outcome Assessment, Health Care; Platelet Aggregation Inhibitors; Prognosis; Risk Assessment; Severity of Illness Index; Survival Rate; Ticlopidine; Transcatheter Aortic Valve Replacement | 2014 |
Active metabolite concentration of clopidogrel in patients taking different doses of aspirin: results of the interaction trial.
Topics: Activation, Metabolic; Aged; Aspirin; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Administration Schedule; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Female; Genotype; Humans; Male; Middle Aged; Phenotype; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine | 2015 |
Platelet reactivity after receiving clopidogrel compared with ticagrelor in patients with kidney failure treated with hemodialysis: a randomized crossover study.
Topics: Adenosine; Adult; Aspirin; Clopidogrel; Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Renal Dialysis; Single-Blind Method; Thrombosis; Ticagrelor; Ticlopidine; Treatment Outcome | 2015 |
Relationship between degree of left ventricular dysfunction, symptom status, and risk of embolic events in patients with atrial fibrillation and heart failure.
Topics: Administration, Oral; Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Biphenyl Compounds; Clopidogrel; Female; Heart Failure; Humans; Irbesartan; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Proportional Hazards Models; Stroke; Tetrazoles; Thromboembolism; Ticlopidine; Treatment Outcome; Ventricular Dysfunction, Left | 2015 |
Statistical analysis plan for the 'Triple Antiplatelets for Reducing Dependency after Ischaemic Stroke' (TARDIS) trial.
Topics: Aspirin; Brain Ischemia; Clopidogrel; Dipyridamole; Double-Blind Method; Female; Humans; International Cooperation; Male; Outcome Assessment, Health Care; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2015 |
Comparison of the antiplatelet effect of clopidogrel hydrogenosulfate and clopidogrel besylate in patients with stable coronary artery disease.
Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Female; Heterozygote; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Prospective Studies; Ticlopidine | 2015 |
Impact of clinical presentation on ischaemic and bleeding outcomes in patients receiving 6- or 24-month duration of dual-antiplatelet therapy after stent implantation: a pre-specified analysis from the PRODIGY (Prolonging Dual-Antiplatelet Treatment After
Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Hemorrhage; Humans; Hyperplasia; Male; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prognosis; Stents; Stroke; Ticlopidine; Tunica Intima | 2015 |
Zotarolimus-eluting versus bare-metal stents in uncertain drug-eluting stent candidates.
Topics: Aged; Aged, 80 and over; Aspirin; Biocompatible Materials; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; Drug-Eluting Stents; Female; Hemorrhage; Humans; Immunosuppressive Agents; Male; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Complications; Risk Assessment; Risk Factors; Sirolimus; Ticlopidine; Treatment Outcome | 2015 |
Glycated albumin predicts the effect of dual and single antiplatelet therapy on recurrent stroke.
Topics: Aged; Aspirin; Biomarkers; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Glycated Serum Albumin; Glycation End Products, Advanced; Humans; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Recurrence; Serum Albumin; Stroke; Ticlopidine | 2015 |
Reduced Effect of Aspirin and Clopidogrel Following Hybrid Coronary Revascularization.
Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Female; Follow-Up Studies; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Prospective Studies; Ticlopidine | 2015 |
A review of antithrombotic therapy and the rationale and design of the randomized edoxaban in patients with peripheral artery disease (ePAD) trial adding edoxaban or clopidogrel to aspirin after femoropopliteal endovascular intervention.
Topics: Aged; Angioplasty; Aspirin; Clopidogrel; Drug Therapy, Combination; Europe; Factor Xa Inhibitors; Female; Femoral Artery; Fibrinolytic Agents; Hemorrhage; Humans; Israel; Male; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Popliteal Artery; Pyridines; Research Design; Risk Factors; Stents; Thiazoles; Ticlopidine; Time Factors; Treatment Outcome; United States | 2015 |
Left Ventricular Geometry on Transthoracic Echocardiogram and Prognosis after Lacunar Stroke: The SPS3 Trial.
Topics: Aged; Aspirin; Clopidogrel; Echocardiography; Female; Heart Ventricles; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Platelet Aggregation Inhibitors; Prognosis; Recurrence; Risk Factors; Secondary Prevention; Stroke, Lacunar; Ticlopidine | 2015 |
Discriminatory power of the intraoperative cell salvage use in the prediction of platelet and plasma transfusion in patients undergoing cardiac surgery.
Topics: Aged; Aorta; Aspirin; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Clopidogrel; Female; Humans; Male; Middle Aged; Operative Blood Salvage; Plasma; Platelet Transfusion; Ticlopidine | 2015 |
Study design of the influence of SErotonin inhibition on patients with RENAl impairment or diabetes undergoing drug-eluting stent implantation (SERENADE) study: A multicenter, open-label, prospective, randomized study.
Topics: Aspirin; Clopidogrel; Coronary Angiography; Coronary Restenosis; Diabetes Mellitus; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Hepatic Insufficiency; Humans; Male; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prospective Studies; Renal Insufficiency, Chronic; Republic of Korea; Research Design; Serotonin Antagonists; Succinates; Ticlopidine | 2015 |
Duration of Triple Therapy in Patients Requiring Oral Anticoagulation After Drug-Eluting Stent Implantation: The ISAR-TRIPLE Trial.
Topics: Aged; Aspirin; Clopidogrel; Drug-Eluting Stents; Female; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors; Treatment Outcome | 2015 |
Stent Thrombosis and Dual Antiplatelet Therapy Interruption With Everolimus-Eluting Stents: Insights From the Xience V Coronary Stent System Trials.
Topics: Aged; Aspirin; Clopidogrel; Coronary Thrombosis; Drug Combinations; Drug-Eluting Stents; Everolimus; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Ticlopidine; Time Factors; Withholding Treatment | 2015 |
Clopidogrel With Aspirin in Acute Minor Stroke or Transient Ischemic Attack (CHANCE) Trial: One-Year Outcomes.
Topics: Aged; Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Ischemic Attack, Transient; Male; Middle Aged; Stroke; Ticlopidine; Treatment Outcome | 2015 |
Rationale and design of the RT-AF study: Combination of rivaroxaban and ticagrelor in patients with atrial fibrillation and coronary artery disease undergoing percutaneous coronary intervention.
Topics: Adenosine; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Hemorrhage; Humans; Percutaneous Coronary Intervention; Research Design; Rivaroxaban; Ticagrelor; Ticlopidine; Warfarin | 2015 |
Preoperative platelet aggregation predicts perioperative blood loss and rethoracotomy for bleeding in patients receiving dual antiplatelet treatment prior to coronary surgery.
Topics: Aspirin; Blood Loss, Surgical; Clopidogrel; Coronary Artery Bypass; Drug Combinations; Female; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Postoperative Hemorrhage; Premedication; Prognosis; Reoperation; Reproducibility of Results; Sensitivity and Specificity; Thoracic Surgery; Thrombosis; Ticlopidine; Treatment Outcome | 2015 |
The effects of proton pump inhibition on patient-reported severity of dyspepsia when receiving dual anti-platelet therapy with clopidogrel and low-dose aspirin: analysis from the Clopidogrel and the Optimization of Gastrointestinal Events Trial.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Dyspepsia; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine; Young Adult | 2015 |
Ankaferd blood stopper decreases postoperative bleeding and number of transfusions in patients treated with clopidogrel: a double-blind, placebo-controlled, randomized clinical trial.
Topics: Aged; Aspirin; Blood Transfusion; Clopidogrel; Coronary Artery Bypass; Double-Blind Method; Female; Hemostatics; Humans; Male; Middle Aged; Plant Extracts; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Premedication; Ticlopidine | 2015 |
Is routine post-procedural anticoagulation warranted after primary percutaneous coronary intervention in ST-segment elevation myocardial infarction? Insights from the HORIZONS-AMI trial.
Topics: Aged; Antithrombins; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug-Eluting Stents; Electrocardiography; Female; Fibrinolytic Agents; Follow-Up Studies; Heparin; Hirudins; Humans; Male; Middle Aged; Peptide Fragments; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Postoperative Care; Postoperative Complications; Prospective Studies; Recombinant Proteins; Secondary Prevention; ST Elevation Myocardial Infarction; Survival Rate; Thrombolytic Therapy; Ticlopidine; Treatment Outcome | 2017 |
Assessment of efficacy of single dose acetylsalicylic acid over a 24-hour period.
Topics: Aged; Aspirin; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2015 |
Ticagrelor Versus Clopidogrel in Black Patients With Stable Coronary Artery Disease: Prospective, Randomized, Open-Label, Multiple-Dose, Crossover Pilot Study.
Topics: Adenosine; Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cross-Over Studies; Female; Humans; Male; Middle Aged; Pilot Projects; Platelet Function Tests; Prospective Studies; Purinergic P2Y Receptor Antagonists; Ticagrelor; Ticlopidine | 2015 |
Stopping antiplatelet medication before coronary artery bypass graft surgery: is there an optimal timing to minimize bleeding?
Topics: Aged; Aspirin; Blood Loss, Surgical; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Drug Therapy, Combination; Female; Humans; Linear Models; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Platelet Transfusion; Postoperative Hemorrhage; Prospective Studies; Risk Assessment; Sensitivity and Specificity; Ticlopidine; Time Factors; Treatment Outcome; Withholding Treatment | 2015 |
Effect of clopidogrel with aspirin on functional outcome in TIA or minor stroke: CHANCE substudy.
Topics: Aged; Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Outcome Assessment, Health Care; Platelet Aggregation Inhibitors; Quality of Life; Stroke; Ticlopidine | 2015 |
Temporal variability in the antiplatelet effects of clopidogrel and aspirin after elective drug-eluting stent implantation. An ADAPT-DES substudy.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Blood Vessel Prosthesis Implantation; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Elective Surgical Procedures; Female; Germany; Humans; Male; Middle Aged; Observer Variation; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Receptors, Purinergic P2Y12; Ticlopidine | 2015 |
Effects of CYP2C19 Polymorphism on Endothelial Function, Arterial Stiffness and Inflammation in Coronary Artery Disease Patients Under Clopidogrel Treatment.
Topics: Aged; Aged, 80 and over; Aspirin; Brachial Artery; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Endothelium, Vascular; Female; Genotype; Humans; Inflammation; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Real-Time Polymerase Chain Reaction; Ticlopidine; Vascular Stiffness | 2015 |
Ticagrelor versus clopidogrel in Chinese patients with acute coronary syndrome: A pharmacodynamic analysis.
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Clopidogrel; Follow-Up Studies; Humans; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Ticagrelor; Ticlopidine | 2015 |
Dual antiplatelet therapy in stroke and ICAS: Subgroup analysis of CHANCE.
Topics: Aged; Aspirin; Clopidogrel; Constriction, Pathologic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Intracranial Arterial Diseases; Ischemic Attack, Transient; Magnetic Resonance Angiography; Male; Middle Aged; Platelet Aggregation Inhibitors; Recurrence; Stroke; Ticlopidine; Treatment Outcome | 2015 |
The Pharmacogenomics of Anti-Platelet Intervention (PAPI) Study: Variation in Platelet Response to Clopidogrel and Aspirin.
Topics: Adult; Age Factors; Amish; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Pharmacogenetics; Platelet Aggregation; Platelet Aggregation Inhibitors; Sex Factors; Ticlopidine; Time Factors | 2016 |
Does the Stenting Versus Aggressive Medical Therapy Trial Support Stenting for Subgroups With Intracranial Stenosis?
Topics: Angioplasty; Aspirin; Carotid Artery, Internal; Carotid Stenosis; Clopidogrel; Constriction, Pathologic; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Middle Cerebral Artery; Platelet Aggregation Inhibitors; Proportional Hazards Models; Risk Reduction Behavior; Stents; Stroke; Ticlopidine; Treatment Outcome; Vertebrobasilar Insufficiency | 2015 |
Combined clopidogrel-aspirin treatment for high risk TIA or minor stroke does not increase cerebral microbleeds.
Topics: Aged; Aspirin; Cerebral Cortex; Cerebral Hemorrhage; Clopidogrel; Drug Therapy, Combination; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Stroke; Ticlopidine; Treatment Outcome | 2015 |
Comparative effect on platelet function of a fixed-dose aspirin and clopidogrel combination versus separate formulations in patients with coronary artery disease: A phase IV, multicenter, prospective, 4-week non-inferiority trial.
Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Drug Combinations; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Ticlopidine; Treatment Outcome | 2016 |
Antiplatelet Efficacy of Fixed-Dose Aspirin-Clopidogrel Combination in Patients with Stable Coronary Artery Disease Treated with Drug-Eluting Stent Implantation.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Combinations; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Ticlopidine; Treatment Outcome; Young Adult | 2015 |
Effects of CYP2C19 allelic variants on inhibition of platelet aggregation and major adverse cardiovascular events in Japanese patients with acute coronary syndrome: The PRASFIT-ACS study.
Topics: Acute Coronary Syndrome; Aged; Alleles; Aspirin; Clopidogrel; Cytochrome P-450 CYP2C19; Double-Blind Method; Female; Genotype; Hemorrhage; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Pharmacogenomic Variants; Phenotype; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Ticlopidine | 2016 |
Association between Antiplatelet or Anticoagulant Drugs and Retinal or Subretinal Hemorrhage in the Comparison of Age-Related Macular Degeneration Treatments Trials.
Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Anticoagulants; Aspirin; Bevacizumab; Cardiovascular Diseases; Clopidogrel; Female; Fluorescein Angiography; Humans; Hypertension; Intravitreal Injections; Male; Odds Ratio; Platelet Aggregation Inhibitors; Ranibizumab; Retinal Hemorrhage; Risk Factors; Ticlopidine; Tomography, Optical Coherence; Vascular Endothelial Growth Factor A; Warfarin; Wet Macular Degeneration | 2016 |
Esomeprazole and rabeprazole did not reduce antiplatelet effects of aspirin/clopidogrel dual therapy in patients undergoing percutaneous coronary intervention: a prospective, randomized, case-control study.
Topics: Aged; Aspirin; Case-Control Studies; Cell Adhesion Molecules; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Esomeprazole; Female; Humans; Male; Microfilament Proteins; Middle Aged; Percutaneous Coronary Intervention; Phosphoproteins; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Proton Pump Inhibitors; Rabeprazole; Ticlopidine | 2016 |
Effect of Clopidogrel and Aspirin vs Aspirin Alone on Migraine Headaches After Transcatheter Atrial Septal Defect Closure: The CANOA Randomized Clinical Trial.
Topics: Aspirin; Cardiac Catheterization; Cardiac Surgical Procedures; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Headache Disorders, Secondary; Heart Septal Defects, Atrial; Humans; Male; Middle Aged; Migraine Disorders; Platelet Aggregation Inhibitors; Regression Analysis; Ticlopidine; Treatment Outcome | 2015 |
Achieved Blood Pressure and Outcomes in the Secondary Prevention of Small Subcortical Strokes Trial.
Topics: Aspirin; Blood Pressure; Blood Pressure Determination; Clopidogrel; Drug Therapy, Combination; Female; Humans; Hypertension; Magnetic Resonance Imaging; Male; Middle Aged; Platelet Aggregation Inhibitors; Recurrence; Secondary Prevention; Severity of Illness Index; Stroke, Lacunar; Ticlopidine; Treatment Outcome | 2016 |
Effects of dabigatran on the cellular and protein phase of coagulation in patients with coronary artery disease on dual antiplatelet therapy with aspirin and clopidogrel. Results from a prospective, randomised, double-blind, placebo-controlled study.
Topics: Administration, Oral; Aged; Anticoagulants; Aspirin; Blood Coagulation; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 Enzyme System; Dabigatran; Double-Blind Method; Electrodes; Female; Humans; Light; Male; Middle Aged; Nephelometry and Turbidimetry; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Thrombelastography; Thrombosis; Ticlopidine; Vitamin K | 2016 |
Incremental Value of the CRUSADE, ACUITY, and HAS-BLED Risk Scores for the Prediction of Hemorrhagic Events After Coronary Stent Implantation in Patients Undergoing Long or Short Duration of Dual Antiplatelet Therapy.
Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proportional Hazards Models; Risk Assessment; Stents; Ticlopidine | 2015 |
Effects of P2Y12 receptor inhibition with or without aspirin on hemostatic system activation: a randomized trial in healthy subjects.
Topics: Adenosine; Adolescent; Adult; Area Under Curve; Aspirin; Austria; beta-Thromboglobulin; Biomarkers; Bleeding Time; Blood Platelets; Clopidogrel; Double-Blind Method; Healthy Volunteers; Hemostasis; Humans; Male; Middle Aged; Peptide Fragments; Platelet Aggregation Inhibitors; Predictive Value of Tests; Prothrombin; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; ROC Curve; Ticagrelor; Ticlopidine; Time Factors; Young Adult | 2016 |
Evaluation of the incremental prognostic value of the combination of CYP2C19 poor metabolizer status and ABCB1 3435 TT polymorphism over conventional risk factors for cardiovascular events after drug-eluting stent implantation in East Asians.
Topics: Aged; Aged, 80 and over; Asia, Eastern; Asian People; Aspirin; ATP Binding Cassette Transporter, Subfamily B; Clopidogrel; Cytochrome P-450 CYP2C19; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Mutation; Percutaneous Coronary Intervention; Pharmacogenomic Variants; Platelet Aggregation Inhibitors; Prognosis; Risk Factors; Ticlopidine | 2016 |
Antiplatelet Therapy in Carotid Artery Stenting and Carotid Endarterectomy in the Asymptomatic Carotid Surgery Trial-2.
Topics: Aspirin; Carotid Artery, Common; Carotid Stenosis; Clopidogrel; Dose-Response Relationship, Drug; Endarterectomy, Carotid; Follow-Up Studies; Humans; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Stents; Stroke; Ticlopidine; Treatment Outcome | 2016 |
Outcomes of Patients With Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention Receiving an Oral Anticoagulant and Dual Antiplatelet Therapy: A Comparison of Clopidogrel Versus Prasugrel From the TRANSLATE-ACS Study.
Topics: Administration, Oral; Aged; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Hemorrhage; Humans; Incidence; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Retrospective Studies; Risk Assessment; Risk Factors; Survival Rate; Ticlopidine; Time Factors; Treatment Outcome; United States | 2015 |
Differences in Whole Blood Platelet Aggregation at Baseline and in Response to Aspirin and Aspirin Plus Clopidogrel in Patients With Versus Without Chronic Kidney Disease.
Topics: Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Renal Insufficiency, Chronic; Thrombosis; Ticlopidine; Treatment Outcome | 2016 |
Secondary prevention of cardiogenic arterial thromboembolism in the cat: The double-blind, randomized, positive-controlled feline arterial thromboembolism; clopidogrel vs. aspirin trial (FAT CAT).
Topics: Animals; Aspirin; Cat Diseases; Cats; Clopidogrel; Double-Blind Method; Male; Platelet Aggregation Inhibitors; Thromboembolism; Ticlopidine | 2015 |
Six Versus 12 Months of Dual Antiplatelet Therapy After Implantation of Biodegradable Polymer Sirolimus-Eluting Stent: Randomized Substudy of the I-LOVE-IT 2 Trial.
Topics: Absorbable Implants; Aged; Antibiotics, Antineoplastic; Aspirin; Clopidogrel; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prospective Studies; Sirolimus; Ticlopidine | 2016 |
[Argatroban, Aspirin, and Clopidogrel Combination Therapy for Acute Penetrating Artery Infarction: A Pilot Study].
Topics: Acute Disease; Aged; Arginine; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Humans; Infarction; Male; Middle Aged; Pilot Projects; Pipecolic Acids; Platelet Aggregation Inhibitors; Prospective Studies; Stroke; Sulfonamides; Ticlopidine; Treatment Outcome | 2016 |
Effectiveness of platelet inhibition on major adverse cardiac events in non-cardiac surgery after percutaneous coronary intervention: a prospective cohort study.
Topics: Aged; Aspirin; Cardiomyopathy, Dilated; Clopidogrel; Cohort Studies; Female; Heart Diseases; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Complications; Prospective Studies; Surgical Procedures, Operative; Ticlopidine; Treatment Outcome; Troponin I | 2016 |
Rationale and design of POPular-TAVI: antiPlatelet therapy fOr Patients undergoing Transcatheter Aortic Valve Implantation.
Topics: Administration, Oral; Aortic Valve Stenosis; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Europe; Follow-Up Studies; Humans; Incidence; Platelet Aggregation Inhibitors; Postoperative Complications; Preoperative Care; Prospective Studies; Survival Rate; Thromboembolism; Ticlopidine; Time Factors; Transcatheter Aortic Valve Replacement; Treatment Outcome | 2016 |
Morphological classification of penetrating artery pontine infarcts and association with risk factors and prognosis: The SPS3 trial.
Topics: Antihypertensive Agents; Aspirin; Cerebral Infarction; Clopidogrel; Constriction, Pathologic; Double-Blind Method; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Observer Variation; Platelet Aggregation Inhibitors; Pons; Prognosis; Recurrence; Reproducibility of Results; Risk Factors; Stroke, Lacunar; Ticlopidine; Treatment Outcome | 2016 |
Durable Clinical Effectiveness With Paclitaxel-Eluting Stents in the Femoropopliteal Artery: 5-Year Results of the Zilver PTX Randomized Trial.
Topics: Adult; Aged; Angioplasty; Anticoagulants; Arterial Occlusive Diseases; Aspirin; Clopidogrel; Combined Modality Therapy; Disease Progression; Disease-Free Survival; Drug-Eluting Stents; Equipment Failure; Female; Femoral Artery; Follow-Up Studies; Humans; Intermittent Claudication; Ischemia; Male; Middle Aged; Paclitaxel; Popliteal Artery; Recurrence; Stents; Ticlopidine; Vascular Patency | 2016 |
Spontaneous MI After Non-ST-Segment Elevation Acute Coronary Syndrome Managed Without Revascularization: The TRILOGY ACS Trial.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Coronary Angiography; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electrocardiography; Female; Follow-Up Studies; Global Health; Humans; Incidence; Male; Middle Aged; Myocardial Infarction; Myocardial Revascularization; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Proportional Hazards Models; Risk Assessment; Survival Rate; Ticlopidine; Time Factors; Treatment Outcome | 2016 |
Impact of proton pump inhibitors on clinical outcomes in patients treated with a 6- or 24-month dual-antiplatelet therapy duration: Insights from the PROlonging Dual-antiplatelet treatment after Grading stent-induced Intimal hyperplasia studY trial.
Topics: Administration, Oral; Aged; Aspirin; Clopidogrel; Coronary Vessels; Drug Therapy, Combination; Electrocardiography; Female; Follow-Up Studies; Graft Occlusion, Vascular; Humans; Hyperplasia; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Stents; Ticlopidine; Time Factors; Treatment Outcome; Tunica Intima | 2016 |
A randomized trial to compare the safety of rivaroxaban vs aspirin in addition to either clopidogrel or ticagrelor in acute coronary syndrome: The design of the GEMINI-ACS-1 phase II study.
Topics: Acute Coronary Syndrome; Adenosine; Adolescent; Adult; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Factor Xa Inhibitors; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Purinergic P2Y Receptor Antagonists; Rivaroxaban; Ticagrelor; Ticlopidine; Treatment Outcome; Young Adult | 2016 |
Treatment Effect of Clopidogrel Plus Aspirin Within 12 Hours of Acute Minor Stroke or Transient Ischemic Attack.
Topics: Aged; Aspirin; Chi-Square Distribution; China; Clopidogrel; Disease Progression; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Hemorrhage; Humans; Ischemic Attack, Transient; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Proportional Hazards Models; Prospective Studies; Recurrence; Risk Factors; Secondary Prevention; Severity of Illness Index; Stroke; Ticlopidine; Time Factors; Time-to-Treatment; Treatment Outcome | 2016 |
Association between insulin receptor substrate-1 polymorphisms and high platelet reactivity with clopidogrel therapy in coronary artery disease patients with type 2 diabetes mellitus.
Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus, Type 2; Drug Resistance; Drug Therapy, Combination; Female; Flow Cytometry; Gene Frequency; Haplotypes; Humans; Insulin Receptor Substrate Proteins; Male; Middle Aged; P-Selectin; Percutaneous Coronary Intervention; Pharmacogenetics; Phenotype; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Single Nucleotide; Ticlopidine; Time Factors; Treatment Outcome | 2016 |
Proton-Pump Inhibitors Reduce Gastrointestinal Events Regardless of Aspirin Dose in Patients Requiring Dual Antiplatelet Therapy.
Topics: Aged; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Dyspepsia; Female; Gastrointestinal Hemorrhage; Humans; Intestinal Obstruction; Intestinal Perforation; Male; Middle Aged; Myocardial Infarction; Myocardial Revascularization; Omeprazole; Pain; Peptic Ulcer; Platelet Aggregation Inhibitors; Prospective Studies; Proton Pump Inhibitors; Stroke; Ticlopidine | 2016 |
Comparison of dual antiplatelet therapy prescribed as one-pill versus two-pill regimen. A pooled analysis of individual patient data from the three MR-CAPCIS trials.
Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Combinations; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Function Tests; Republic of Korea; Ticlopidine | 2016 |
Effect of prior clopidogrel use on outcomes in medically managed acute coronary syndrome patients.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Hemorrhage; Hospitalization; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Proportional Hazards Models; Risk Assessment; Risk Factors; Stroke; Ticlopidine; Time Factors; Treatment Outcome | 2016 |
Role of stent type and of duration of dual antiplatelet therapy in patients with chronic kidney disease undergoing percutaneous coronary interventions. Is bare metal stent implantation still a justifiable choice? A post-hoc analysis of the all comer PRODI
Topics: Aged; Aged, 80 and over; Aspirin; Clinical Decision-Making; Clopidogrel; Coronary Thrombosis; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Male; Metals; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prosthesis Design; Renal Insufficiency, Chronic; Stents; Ticlopidine; Time Factors; Treatment Outcome | 2016 |
Ticagrelor Improves Peripheral Arterial Function in Acute Coronary Syndrome Patients: Relationship With Adenosine Plasma Level.
Topics: Acute Coronary Syndrome; Adenosine; Aged; Arteries; Aspirin; Biomarkers; Clopidogrel; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Extremities; Female; Follow-Up Studies; Humans; Male; Middle Aged; Peripheral Arterial Disease; Prospective Studies; Severity of Illness Index; Survival Rate; Ticagrelor; Ticlopidine; Treatment Outcome | 2016 |
Anti-platelet drugs attenuate the expansion of circulating CD14highCD16+ monocytes under pro-inflammatory conditions.
Topics: Adult; Aspirin; Biomarkers; C-Reactive Protein; Cell Proliferation; Clopidogrel; Cytokines; Female; Flow Cytometry; GPI-Linked Proteins; Humans; Immunologic Factors; Inflammation; Inflammation Mediators; Influenza Vaccines; Lipopolysaccharide Receptors; London; Male; Monocytes; P-Selectin; Phenotype; Platelet Aggregation Inhibitors; Receptors, IgG; Ticlopidine; Vaccination | 2016 |
Inferiority of ticagrelor in the PHILO trial: Play of chance in East Asians or nightmare confirmation of PLATO-USA?
Topics: Acute Coronary Syndrome; Adenosine; Asian People; Aspirin; Black People; Clopidogrel; Hemorrhage; Humans; Japan; Ticagrelor; Ticlopidine; Treatment Outcome; United States; White People | 2016 |
Impact of Anemia on Platelet Reactivity and Ischemic and Bleeding Risk: From the Assessment of Dual Antiplatelet Therapy With Drug-Eluting Stents Study.
Topics: Aged; Anemia; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Europe; Female; Hemorrhage; Humans; Incidence; Male; Middle Aged; Myocardial Ischemia; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Registries; Risk Assessment; Risk Factors; Survival Rate; Ticlopidine; United States | 2016 |
Adjunctive loading dose of cilostazol in preventing periprocedural myocardial infarction.
Topics: Aged; Aspirin; Biomarkers; Chi-Square Distribution; China; Cilostazol; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Incidence; Logistic Models; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Risk Factors; Tetrazoles; Ticlopidine; Time Factors; Treatment Outcome | 2016 |
[Prevalence of acetylsalicylic acid (ASA) - low response in vascular surgery].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Arterial Occlusive Diseases; Aspirin; Carotid Stenosis; Clopidogrel; Cross-Sectional Studies; Drug Therapy, Combination; Female; Humans; Leukocyte Count; Long-Term Care; Male; Middle Aged; Pantoprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Postoperative Complications; Risk Factors; Ticlopidine | 2016 |
Efficacy and Safety of Proton-Pump Inhibitors in High-Risk Cardiovascular Subsets of the COGENT Trial.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Omeprazole; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine; Treatment Outcome | 2016 |
Assessment of platelet function in healthy cats in response to commonly prescribed antiplatelet drugs using three point-of-care platelet function tests.
Topics: Administration, Oral; Animals; Aspirin; Blood Coagulation Tests; Blood Platelets; Cats; Clopidogrel; Female; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Ticlopidine | 2017 |
Comparison of the antiplatelet effect of clopidogrel benzene sulfonate and clopidogrel hydrogen sulfate in stable coronary heart disease.
Topics: Adult; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Drug Combinations; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine | 2016 |
Association Between Very Low Levels of High-Density Lipoprotein Cholesterol and Long-term Outcomes of Patients With Acute Coronary Syndrome Treated Without Revascularization: Insights From the TRILOGY ACS Trial.
Topics: Acute Coronary Syndrome; Aged; Angina, Unstable; Aspirin; Biomarkers; Cholesterol, HDL; Clopidogrel; Down-Regulation; Drug Therapy, Combination; Dyslipidemias; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Non-ST Elevated Myocardial Infarction; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Risk Assessment; Risk Factors; Stroke; Ticlopidine; Time Factors; Treatment Outcome | 2016 |
6-Month Versus 12-Month Dual-Antiplatelet Therapy Following Long Everolimus-Eluting Stent Implantation: The IVUS-XPL Randomized Clinical Trial.
Topics: Aspirin; Cardiovascular Agents; Clopidogrel; Coronary Thrombosis; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Everolimus; Hemorrhage; Humans; Intention to Treat Analysis; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prosthesis Design; Republic of Korea; Risk Factors; Stroke; Ticlopidine; Time Factors; Treatment Outcome | 2016 |
Impaired biological response to aspirin in therapeutic hypothermia comatose patients resuscitated from out-of-hospital cardiac arrest.
Topics: Acute Coronary Syndrome; Administration, Intravenous; Administration, Oral; Adult; Aged; Aspirin; Cardiopulmonary Resuscitation; Clopidogrel; Coma; Female; Humans; Hypothermia, Induced; Male; Middle Aged; Out-of-Hospital Cardiac Arrest; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Prospective Studies; Ticlopidine | 2016 |
[The possibility of selecting optimal antiplatelet therapy in patients with coronary heart disease in terms of CYP2C19 polymorphism].
Topics: Aspirin; Clopidogrel; Coronary Disease; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Prospective Studies; Ticlopidine | 2016 |
Risks and Benefits of Dual Antiplatelet Therapy Beyond 12 Months After Coronary Stenting: A Prospective Randomized Cohort Study.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Postoperative Complications; Prospective Studies; Stroke; Ticlopidine; Time Factors; Treatment Outcome | 2016 |
Efficacy and Safety of Vinpocetine as Part of Treatment for Acute Cerebral Infarction: A Randomized, Open-Label, Controlled, Multicenter CAVIN (Chinese Assessment for Vinpocetine in Neurology) Trial.
Topics: Aged; Anticoagulants; Aspirin; Cerebral Infarction; Cerebrovascular Circulation; China; Clopidogrel; Cognition; Female; Humans; Male; Middle Aged; Neuroprotective Agents; Neuropsychological Tests; Platelet Aggregation Inhibitors; Quality of Life; Stroke; Ticlopidine; Ultrasonography, Doppler, Transcranial; Vinca Alkaloids | 2016 |
Impact of glycoprotein IIb/IIIa inhibitors on the efficacy and safety of ticagrelor compared with clopidogrel in patients with acute coronary syndromes: Analysis from the Platelet Inhibition and Patient Outcomes (PLATO) Trial.
Topics: Abciximab; Acute Coronary Syndrome; Adenosine; Aged; Antibodies, Monoclonal; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Eptifibatide; Female; Graft Occlusion, Vascular; Hemorrhage; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Myocardial Infarction; Peptides; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Purinergic P2Y Receptor Antagonists; Stroke; Thrombosis; Ticagrelor; Ticlopidine; Tirofiban; Tyrosine | 2016 |
Safety and efficacy of policosanol in patients with high on-treatment platelet reactivity after drug-eluting stent implantation: two-year follow-up results.
Topics: Acute Coronary Syndrome; Aged; Aspirin; China; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Fatty Alcohols; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome | 2016 |
Association Between CYP2C19 Loss-of-Function Allele Status and Efficacy of Clopidogrel for Risk Reduction Among Patients With Minor Stroke or Transient Ischemic Attack.
Topics: Aged; Alleles; Asian People; Aspirin; China; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Female; Follow-Up Studies; Gene Silencing; Genotype; Hemorrhage; Heterozygote; Humans; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Secondary Prevention; Stroke; Ticlopidine; Time Factors; Treatment Outcome | 2016 |
A Cost-Effectiveness Analysis of Clopidogrel for Patients with Non-ST-Segment Elevation Acute Coronary Syndrome in China.
Topics: Acute Coronary Syndrome; Aspirin; China; Clopidogrel; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combination; Female; Humans; Male; Markov Chains; Middle Aged; Platelet Aggregation Inhibitors; Quality-Adjusted Life Years; Ticlopidine | 2016 |
Recurrent Ischemic Lesions After Acute Atherothrombotic Stroke: Clopidogrel Plus Aspirin Versus Aspirin Alone.
Topics: Aged; Aspirin; Atherosclerosis; Brain; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Platelet Aggregation Inhibitors; Secondary Prevention; Stroke; Thrombosis; Ticlopidine | 2016 |
The curative effect comparison of two kinds of therapeutic regimens on decreasing the relative intensity of microembolic signal in CLAIR trial.
Topics: Aspirin; Brain Ischemia; Carotid Stenosis; Cerebral Arterial Diseases; Clopidogrel; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Intracranial Embolism; Male; Middle Aged; Platelet Aggregation Inhibitors; Recurrence; Single-Blind Method; Stroke; Ticlopidine; Treatment Outcome | 2016 |
Rationale and design of the SAFE-A study: SAFety and Effectiveness trial of Apixaban use in association with dual antiplatelet therapy in patients with atrial fibrillation undergoing percutaneous coronary intervention.
Topics: Aspirin; Atrial Fibrillation; Blood Transfusion; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Factor Xa Inhibitors; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Prospective Studies; Purinergic P2Y Receptor Antagonists; Pyrazoles; Pyridones; Stroke; Ticlopidine | 2017 |
Impact of genetic polymorphisms related to clopidogrel or acetylsalicylic acid pharmacology on clinical outcome in Chinese patients with symptomatic extracranial or intracranial stenosis.
Topics: Aged; Asian People; Aspirin; Carboxylic Ester Hydrolases; Clopidogrel; Constriction, Pathologic; Cytochrome P-450 CYP2C19; Female; Genotype; Humans; Ischemia; Male; Middle Aged; Mutation; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Ticlopidine; Treatment Outcome | 2016 |
Dual Antiplatelet Therapy and Outcomes in Patients With Atrial Fibrillation and Acute Coronary Syndromes Managed Medically Without Revascularization: Insights From the TRILOGY ACS Trial.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Atrial Fibrillation; Chi-Square Distribution; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Hemorrhage; Humans; Kaplan-Meier Estimate; Linear Models; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Proportional Hazards Models; Prospective Studies; Risk Assessment; Risk Factors; Stroke; Ticlopidine; Time Factors; Treatment Outcome | 2016 |
Changes in P2Y12 reaction units after switching treatments from prasugrel to clopidogrel in Japanese patients with acute coronary syndrome followed by elective coronary stenting.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Cytochrome P-450 CYP2C19; Female; Humans; Japan; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Prasugrel Hydrochloride; Prosthesis Implantation; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic; Stents; Ticlopidine | 2017 |
Randomized evaluation of short-term dual antiplatelet therapy in patients with acute coronary syndrome treated with the COMBO dual therapy stent: rationale and design of the REDUCE trial.
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Cause of Death; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Graft Occlusion, Vascular; Hemorrhage; Humans; Mortality; Myocardial Infarction; Myocardial Revascularization; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Stroke; Thrombosis; Ticagrelor; Ticlopidine; Time Factors | 2016 |
Health-related quality of life outcomes with prasugrel among medically managed non-ST-segment elevation acute coronary syndrome patients: Insights from the Targeted Platelet Inhibition to Clarify the Optimal Strategy to Medically Manage Acute Coronary Syn
Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Health Status; Humans; Linear Models; Male; Middle Aged; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Quality of Life; Ticlopidine | 2016 |
Impact of Sex on 2-Year Clinical Outcomes in Patients Treated With 6-Month or 24-Month Dual-Antiplatelet Therapy Duration: A Pre-Specified Analysis From the PRODIGY Trial.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Coronary Thrombosis; Drug Administration Schedule; Drug Therapy, Combination; Female; Hemorrhage; Humans; Italy; Male; Middle Aged; Myocardial Infarction; Neointima; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proportional Hazards Models; Risk Assessment; Risk Factors; Sex Factors; Stents; Stroke; Ticlopidine; Time Factors; Treatment Outcome | 2016 |
Pharmacodynamic effects of a new fixed-dose clopidogrel-aspirin combination compared with separate administration of clopidogrel and aspirin in patients treated with coronary stents: The ACCEL-COMBO trial.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Comorbidity; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Stents; Thrombelastography; Ticlopidine; Treatment Outcome | 2017 |
Abnormal glucose regulation increases stroke risk in minor ischemic stroke or TIA.
Topics: Aged; Aspirin; Blood Glucose; Brain Ischemia; Clopidogrel; Diabetes Complications; Double-Blind Method; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Recurrence; Risk; Stroke; Ticlopidine; Treatment Outcome | 2016 |
Clinical outcomes of dual antiplatelet therapy after implantation of drug-eluting stents in patients with different cardiovascular risk factors.
Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Death, Sudden, Cardiac; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Incidence; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Republic of Korea; Risk Factors; Sirolimus; Ticlopidine; Time Factors | 2017 |
Prevalence and Predictors of Early Discontinuation of Dual-Antiplatelet Therapy After Drug-Eluting Stent Implantation in Korean Population.
Topics: Adult; Aged; Aspirin; Clopidogrel; Coronary Restenosis; Coronary Stenosis; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Male; Middle Aged; Patient Compliance; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prevalence; Republic of Korea; Retrospective Studies; Risk Factors; Ticlopidine; Time Factors; Withholding Treatment; Young Adult | 2016 |
Effect of Estimated Glomerular Filtration Rate Decline on the Efficacy and Safety of Clopidogrel With Aspirin in Minor Stroke or Transient Ischemic Attack: CHANCE Substudy (Clopidogrel in High-Risk Patients With Acute Nondisabling Cerebrovascular Events).
Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Clopidogrel; Comorbidity; Drug Therapy, Combination; Glomerular Filtration Rate; Humans; Ischemic Attack, Transient; Middle Aged; Outcome Assessment, Health Care; Platelet Aggregation Inhibitors; Renal Insufficiency, Chronic; Severity of Illness Index; Stroke; Ticlopidine | 2016 |
Baseline characteristics of the 3096 patients recruited into the 'Triple Antiplatelets for Reducing Dependency after Ischemic Stroke' trial.
Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Female; Humans; Male; Platelet Aggregation Inhibitors; Severity of Illness Index; Stroke; Ticlopidine; Treatment Outcome | 2017 |
Pharmacokinetics and relative bioavailability of fixed-dose combination of clopidogrel and aspirin versus coadministration of individual formulations in healthy Korean men.
Topics: Acute Coronary Syndrome; Administration, Oral; Adult; Area Under Curve; Aspirin; Biological Availability; Clopidogrel; Cross-Over Studies; Drug Combinations; Drug Therapy, Combination; Healthy Volunteers; Humans; Male; Middle Aged; Therapeutic Equivalency; Ticlopidine; Young Adult | 2016 |
A comparison of reduced-dose prasugrel and standard-dose clopidogrel in elderly patients with acute coronary syndromes undergoing early percutaneous revascularization: Design and rationale of the randomized Elderly-ACS 2 study.
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Aspirin; Cause of Death; Clopidogrel; Drug Therapy, Combination; Early Medical Intervention; Female; Hemorrhage; Humans; Male; Mortality; Myocardial Infarction; Patient Readmission; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Recurrence; Stroke; Ticlopidine; Treatment Outcome | 2016 |
Trial design: Rivaroxaban for the prevention of major cardiovascular events after transcatheter aortic valve replacement: Rationale and design of the GALILEO study.
Topics: Aortic Valve Stenosis; Aspirin; Cardiovascular Diseases; Cause of Death; Clopidogrel; Drug Therapy, Combination; Embolism; Factor Xa Inhibitors; Heart Valve Diseases; Humans; Mortality; Myocardial Infarction; Platelet Aggregation Inhibitors; Postoperative Care; Pulmonary Embolism; Rivaroxaban; Stroke; Thrombosis; Ticlopidine; Transcatheter Aortic Valve Replacement; Venous Thrombosis | 2017 |
Effects of various antiplatelet drugs on ex vivo platelet activation induced by equine herpesvirus type 1.
Topics: Animals; Aspirin; Clopidogrel; Cross-Over Studies; Double-Blind Method; Female; Flow Cytometry; Herpesviridae Infections; Herpesvirus 1, Equid; Horse Diseases; Horses; Male; Pentoxifylline; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Theophylline; Ticlopidine | 2016 |
Safety of 6-month duration of dual antiplatelet therapy after percutaneous coronary intervention in patients with acute coronary syndromes: Rationale and design of the Smart Angioplasty Research Team-safety of 6-month duration of Dual Antiplatelet Therapy
Topics: Acute Coronary Syndrome; Adult; Aspirin; Clopidogrel; Drug Monitoring; Drug-Eluting Stents; Everolimus; Female; Hemorrhage; Humans; Immunosuppressive Agents; Male; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Republic of Korea; Sirolimus; Ticlopidine; Time Factors; Treatment Outcome | 2016 |
New single-nucleotide polymorphisms associated with differences in platelet reactivity and their influence on survival in patients with type 2 diabetes treated with acetylsalicylic acid: an observational study.
Topics: Aged; Alleles; Aspirin; Blood Platelets; Clopidogrel; Diabetes Mellitus, Type 2; Female; Genotype; Humans; Inflammation; Male; Middle Aged; Platelet Activation; Polymorphism, Single Nucleotide; Receptors, Thromboxane A2, Prostaglandin H2; Survival Analysis; Ticlopidine | 2017 |
Ischaemic and bleeding outcomes in elderly patients undergoing a prolonged versus shortened duration of dual antiplatelet therapy after percutaneous coronary intervention: insights from the PRODIGY randomised trial.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Complications; Thrombosis; Ticlopidine | 2017 |
The effectiveness and safety of dual antiplatelet therapy in ischemic cerebrovascular disease with intracranial and extracranial arteriostenosis in Chinese patients: A randomized and controlled trail.
Topics: Arterial Occlusive Diseases; Aspirin; China; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Hemorrhage; Humans; Intracranial Arterial Diseases; Male; Middle Aged; Platelet Aggregation Inhibitors; Secondary Prevention; Stroke; Survival Analysis; Ticlopidine; Treatment Outcome | 2017 |
Association of multiple infarctions and ICAS with outcomes of minor stroke and TIA.
Topics: Aged; Aspirin; Brain; Brain Infarction; Brain Ischemia; Clopidogrel; Female; Humans; Image Processing, Computer-Assisted; Intracranial Arteriosclerosis; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Treatment Outcome | 2017 |
Myocardial Infarction Risk After Discontinuation of Thienopyridine Therapy in the Randomized DAPT Study (Dual Antiplatelet Therapy).
Topics: Acute Coronary Syndrome; Aged; Angina, Stable; Aspirin; Clopidogrel; Coronary Thrombosis; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Incidence; Intention to Treat Analysis; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome | 2017 |
Randomized Angiographic and Intravascular Ultrasound Comparison of Dual-Antiplatelet Therapy vs Triple-Antiplatelet Therapy to Reduce Neointimal Tissue Proliferation in Diabetic Patients.
Topics: Aspirin; Cilostazol; Clopidogrel; Comorbidity; Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; Diabetes Mellitus; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Humans; Male; Middle Aged; Neointima; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Sirolimus; Tetrazoles; Ticlopidine; Treatment Outcome | 2017 |
Impact of Glycemic Control on Efficacy of Clopidogrel in Transient Ischemic Attack or Minor Stroke Patients With
Topics: Aged; Aspirin; Clopidogrel; Cytochrome P-450 CYP2C19; Double-Blind Method; Female; Glycated Serum Albumin; Glycation End Products, Advanced; Heterozygote; Humans; Ischemic Attack, Transient; Male; Middle Aged; Outcome Assessment, Health Care; Platelet Aggregation Inhibitors; Recurrence; Risk; Serum Albumin; Stroke; Ticlopidine | 2017 |
Efficacy of cilostazol-based dual antiplatelet treatment in patients undergoing carotid artery stenting.
Topics: Aged; Aged, 80 and over; Aspirin; Carotid Stenosis; Cilostazol; Clopidogrel; Drug Therapy, Combination; Female; Hemorrhage; Humans; Incidence; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Stents; Stroke; Tetrazoles; Ticlopidine | 2017 |
Clinically significant bleeding with low-dose rivaroxaban versus aspirin, in addition to P2Y12 inhibition, in acute coronary syndromes (GEMINI-ACS-1): a double-blind, multicentre, randomised trial.
Topics: Acute Coronary Syndrome; Adenosine; Aged; Aspirin; Clopidogrel; Coronary Angiography; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Factor Xa Inhibitors; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Rivaroxaban; Thrombolytic Therapy; Ticagrelor; Ticlopidine; Treatment Outcome | 2017 |
Impact of dual antiplatelet therapy after coronary artery bypass surgery on 1-year outcomes in the Arterial Revascularization Trial.
Topics: Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Europe; Female; Follow-Up Studies; Humans; Incidence; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Propensity Score; Survival Rate; Ticlopidine; Time Factors; Treatment Outcome | 2017 |
Growth Differentiation Factor 15 at 1 Month After an Acute Coronary Syndrome Is Associated With Increased Risk of Major Bleeding.
Topics: Acute Coronary Syndrome; Adenosine; Aged; Aspirin; Biomarkers; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Growth Differentiation Factor 15; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Predictive Value of Tests; Proportional Hazards Models; Risk Assessment; Risk Factors; Ticagrelor; Ticlopidine; Time Factors; Treatment Outcome; Up-Regulation | 2017 |
Risks and benefits of clopidogrel-aspirin in minor stroke or TIA: Time course analysis of CHANCE.
Topics: Aspirin; Brain Ischemia; China; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Risk; Stroke; Ticlopidine; Time Factors; Treatment Outcome | 2017 |
Extended Duration Dual Antiplatelet Therapy After Coronary Stenting Among Patients With Peripheral Arterial Disease: A Subanalysis of the Dual Antiplatelet Therapy Study.
Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Proportional Hazards Models; Risk Factors; Stents; Stroke; Ticlopidine; Time Factors; Treatment Outcome | 2017 |
Benefit of switching dual antiplatelet therapy after acute coronary syndrome: the TOPIC (timing of platelet inhibition after acute coronary syndrome) randomized study.
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Clopidogrel; Drug Administration Schedule; Drug Combinations; Drug Substitution; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Medication Adherence; Middle Aged; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Tablets; Ticagrelor; Ticlopidine; Time Factors; Treatment Outcome | 2017 |
Aspirin Versus Aspirin Plus Clopidogrel as Antithrombotic Treatment Following Transcatheter Aortic Valve Replacement With a Balloon-Expandable Valve: The ARTE (Aspirin Versus Aspirin + Clopidogrel Following Transcatheter Aortic Valve Implantation) Randomi
Topics: Aged; Aged, 80 and over; Aortic Valve; Aspirin; Balloon Valvuloplasty; Canada; Clopidogrel; Drug Therapy, Combination; Early Termination of Clinical Trials; Europe; Female; Fibrinolytic Agents; Heart Valve Prosthesis; Hemorrhage; Humans; Ischemic Attack, Transient; Kaplan-Meier Estimate; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Prosthesis Design; Risk Factors; South America; Stroke; Thrombosis; Ticlopidine; Time Factors; Transcatheter Aortic Valve Replacement; Treatment Outcome | 2017 |
[IMPACT OF ATORVASTATIN AND ROSUVASTATIN ON RESIDUAL ON-CLOPIDOGREL TREATMENT PLATELET REACTIVITY IN PATIENTS WITH ISCHEMIC HEART DISEASE AND TYPE 2 DIABETES MELLITUS AFTER ACUTE CORONARY SYNDROME].
Topics: Acute Coronary Syndrome; Aspirin; Atorvastatin; Blood Platelets; Clopidogrel; Diabetes Mellitus, Type 2; Drug Interactions; Drug Substitution; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation Inhibitors; Rosuvastatin Calcium; Ticlopidine | 2017 |
Dual antiplatelet therapy in patients with diabetes and acute coronary syndromes managed without revascularization.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Diabetes Mellitus; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Female; Follow-Up Studies; Humans; Male; Myocardial Revascularization; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Ticlopidine; Time Factors; Treatment Outcome | 2017 |
Use of the Dual-Antiplatelet Therapy Score to Guide Treatment Duration After Percutaneous Coronary Intervention.
Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Retrospective Studies; Stents; Ticlopidine; Treatment Outcome | 2017 |
Platelet-related biomarkers and their response to inhibition with aspirin and p2y
Topics: Acute Coronary Syndrome; Adenosine; Aged; Aspirin; Biomarkers; Blood Platelets; CD40 Ligand; Clopidogrel; Female; Humans; Male; Middle Aged; P-Selectin; Platelet Aggregation Inhibitors; Platelet Count; Prospective Studies; Purinergic P2Y Receptor Antagonists; Ticagrelor; Ticlopidine; Time Factors | 2017 |
Short-term efficacy and safety of three different antiplatelet regimens in diabetic patients treated with primary percutaneous coronary intervention: a randomised study.
Topics: Adenosine; Aged; Aspirin; Clopidogrel; Diabetic Cardiomyopathies; Double-Blind Method; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Patient Safety; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; ST Elevation Myocardial Infarction; Ticagrelor; Ticlopidine; Tirofiban; Treatment Outcome; Tyrosine | 2017 |
Morphological and pharmacological determinants of peri-procedural myocardial infarction following elective stent implantation: Optical coherence tomography sub-analysis of the PRASFIT-Elective study.
Topics: Aged; Aspirin; Clopidogrel; Creatine Kinase, MB Form; Double-Blind Method; Elective Surgical Procedures; Female; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Stents; Thrombosis; Ticlopidine; Tomography, Optical Coherence | 2017 |
Dual Antiplatelet Therapy for 6 Versus 18 Months After Biodegradable Polymer Drug-Eluting Stent Implantation.
Topics: Absorbable Implants; Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Humans; Intention to Treat Analysis; Japan; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polymers; Proportional Hazards Models; Prospective Studies; Prosthesis Design; Risk Factors; Stroke; Ticlopidine; Time Factors; Treatment Outcome | 2017 |
6- Versus 24-Month Dual Antiplatelet Therapy After Implantation of Drug-Eluting Stents in Patients Nonresistant to Aspirin: Final Results of the ITALIC Trial (Is There a Life for DES After Discontinuation of Clopidogrel).
Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Female; France; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proportional Hazards Models; Prospective Studies; Prosthesis Design; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome | 2017 |
Rationale and Design for a Randomized Comparison of Efficacy and Safety between Aspirin and Clopidogrel in Atrial Fibrillation Patients with Low Stroke Risk: CESAC-AF trial.
Topics: Aspirin; Atrial Fibrillation; Clopidogrel; Drug Therapy, Combination; Endoscopy, Digestive System; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Research Design; Risk Factors; Stroke; Ticlopidine | 2017 |
Microbleeds in the Secondary Prevention of Small Subcortical Strokes Trial: Stroke, mortality, and treatment interactions.
Topics: Aspirin; Cerebral Hemorrhage; Clopidogrel; Double-Blind Method; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Platelet Aggregation Inhibitors; Recurrence; Risk Factors; Secondary Prevention; Stroke, Lacunar; Ticlopidine | 2017 |
A randomised trial on the effect of anti-platelet therapy on the systemic inflammatory response in human endotoxaemia.
Topics: Adenosine; Administration, Intravenous; Adolescent; Adult; Aspirin; Cells, Cultured; Clopidogrel; Cytokines; Drug Therapy, Combination; Endotoxemia; Endotoxins; Healthy Volunteers; Humans; Inflammation; Inflammation Mediators; Male; Netherlands; Platelet Activation; Platelet Aggregation Inhibitors; Prospective Studies; Purinergic P2Y Receptor Antagonists; Ticagrelor; Ticlopidine; Time Factors; Treatment Outcome; Young Adult | 2017 |
Validation of the DAPT score in patients randomized to 6 or 12 months clopidogrel after predominantly second-generation drug-eluting stents.
Topics: Aged; Aspirin; Clinical Decision-Making; Clopidogrel; Coronary Disease; Coronary Thrombosis; Decision Support Techniques; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Predictive Value of Tests; Proportional Hazards Models; Prosthesis Design; Reproducibility of Results; Risk Factors; Stroke; Ticlopidine; Time Factors; Treatment Outcome | 2017 |
Dual Antithrombotic Therapy with Dabigatran after PCI in Atrial Fibrillation.
Topics: Adenosine; Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Dabigatran; Drug Therapy, Combination; Female; Hemorrhage; Humans; Incidence; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Risk; Ticagrelor; Ticlopidine; Warfarin | 2017 |
SAFE (Sarpogrelate Anplone in Femoro-popliteal artery intervention Efficacy) study: study protocol for a randomized controlled trial.
Topics: Amputation, Surgical; Aspirin; Clinical Protocols; Clopidogrel; Computed Tomography Angiography; Constriction, Pathologic; Drug Therapy, Combination; Endovascular Procedures; Femoral Artery; Hemorrhage; Humans; Limb Salvage; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Popliteal Artery; Prospective Studies; Recurrence; Republic of Korea; Research Design; Risk Factors; Succinates; Ticlopidine; Time Factors; Treatment Outcome; Vascular Patency | 2017 |
Characterization of the Average Daily Ischemic and Bleeding Risk After Primary PCI for STEMI.
Topics: Aged; Aspirin; Clopidogrel; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Risk Assessment; ST Elevation Myocardial Infarction; Stents; Ticlopidine; Time Factors; United States | 2017 |
Anti-platelet effects of epigallocatechin-3-gallate in addition to the concomitant aspirin, clopidogrel or ticagrelor treatment.
Topics: Adult; Aged; Aspirin; Blood Platelets; Catechin; Clopidogrel; Coronary Stenosis; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Republic of Korea; Ticagrelor; Ticlopidine | 2018 |
Comparison of Multiplate, Platelet Function Analyzer-200, and Plateletworks in Healthy Dogs Treated with Aspirin and Clopidogrel.
Topics: Animals; Aspirin; Blood Platelets; Clopidogrel; Dogs; Double-Blind Method; Drug Therapy, Combination; Female; Male; Platelet Aggregation; Platelet Count; Platelet Function Tests; Ticlopidine | 2018 |
Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia (TARDIS): a randomised, open-label, phase 3 superiority trial.
Topics: Acute Disease; Aged; Aspirin; Brain Ischemia; Clopidogrel; Denmark; Dipyridamole; Drug Therapy, Combination; Female; Georgia; Hemorrhage; Humans; Ischemia; Ischemic Attack, Transient; Male; Middle Aged; New Zealand; Platelet Aggregation Inhibitors; Prospective Studies; Recurrence; Research Design; Risk Assessment; Stroke; Thrombolytic Therapy; Ticlopidine; Treatment Outcome; United Kingdom | 2018 |
Tiny Cerebral Aneurysms Can Be Treated Safely and Effectively with Low-Profile Visualized Intraluminal Support Stent-Assisted Coiling or Coiling Alone.
Topics: Adult; Aged; Aneurysm, Ruptured; Aspirin; Clopidogrel; Embolization, Therapeutic; Endovascular Procedures; Female; Follow-Up Studies; Humans; Intracranial Aneurysm; Male; Middle Aged; Platelet Aggregation Inhibitors; Preoperative Care; Prospective Studies; Stents; Thrombosis; Ticlopidine | 2018 |
Another Endovascular Therapy Strategy for Acute Tandem Occlusion: Protect-Expand-Aspiration-Revascularization-Stent (PEARS) Technique.
Topics: Acute Disease; Aged; Aspirin; Carotid Artery Thrombosis; Carotid Artery, Internal; Cerebral Revascularization; Clopidogrel; Endovascular Procedures; Feasibility Studies; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Severity of Illness Index; Stents; Thrombectomy; Ticlopidine; Tirofiban; Treatment Outcome; Tyrosine | 2018 |
A Multicenter, Randomized, Double-Blind, and Placebo-Controlled Study of the Effects of Tongxinluo Capsules in Acute Coronary Syndrome Patients with High On-Treatment Platelet Reactivity.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Blood Platelets; Capsules; Clopidogrel; Double-Blind Method; Drugs, Chinese Herbal; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2018 |
6-month versus 12-month or longer dual antiplatelet therapy after percutaneous coronary intervention in patients with acute coronary syndrome (SMART-DATE): a randomised, open-label, non-inferiority trial.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prospective Studies; Republic of Korea; Ticlopidine; Treatment Outcome | 2018 |
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Hemorrhage; Humans; Ischemia; Ischemic Attack, Transient; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk; Secondary Prevention; Stroke; Ticlopidine | 2018 |
Aspirin plus clopidogrel may reduce the risk of early neurologic deterioration in ischemic stroke patients carrying CYP2C19*2 reduced-function alleles.
Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Female; Heterozygote; Humans; Incidence; Male; Neurodegenerative Diseases; Pharmacogenomic Variants; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Stroke; Ticlopidine | 2018 |
Ticagrelor plus aspirin for 1 month, followed by ticagrelor monotherapy for 23 months vs aspirin plus clopidogrel or ticagrelor for 12 months, followed by aspirin monotherapy for 12 months after implantation of a drug-eluting stent: a multicentre, open-la
Topics: Adenosine; Aged; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Intention to Treat Analysis; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Ticagrelor; Ticlopidine | 2018 |
Beneficial effects of combined administration of Clopidogrel and Aspirin on the levels of proinflammatory cytokines, cardiac function, and prognosis in ST-segment elevation myocardial infarction: A comparative study.
Topics: Aged; Aspirin; Clopidogrel; Cytokines; Drug Therapy, Combination; Female; Heart; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prognosis; ST Elevation Myocardial Infarction; Ticlopidine; Treatment Outcome | 2018 |
Implementation of a Reference-Scaled Average Bioequivalence Approach for Highly Variable Acetylsalicylic Acid in Fixed-Dose Combination with Clopidogrel Versus Enteric Aspirin in Chinese Subjects Under Fasting Conditions: A Phase 1, Open-Label, Randomized
Topics: Acute Coronary Syndrome; Adult; Area Under Curve; Asian People; Aspirin; Clopidogrel; Cross-Over Studies; Drug Combinations; Drug Therapy, Combination; Female; Healthy Volunteers; Humans; Male; Therapeutic Equivalency; Thrombosis; Ticlopidine | 2020 |
Effect of Ticagrelor Monotherapy vs Ticagrelor With Aspirin on Major Bleeding and Cardiovascular Events in Patients With Acute Coronary Syndrome: The TICO Randomized Clinical Trial.
Topics: Acute Coronary Syndrome; Aspirin; Cardiovascular Diseases; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Sirolimus; Ticlopidine | 2020 |
Comparison of one-month versus twelve-month dual antiplatelet therapy after implantation of drug-eluting stents guided by either intravascular ultrasound or angiography in patients with acute coronary syndrome: rationale and design of prospective, multice
Topics: Acute Coronary Syndrome; Adult; Aspirin; Coronary Angiography; Drug-Eluting Stents; Dual Anti-Platelet Therapy; Duration of Therapy; Female; Hemorrhage; Humans; Male; Multicenter Studies as Topic; Outcome and Process Assessment, Health Care; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Complications; Randomized Controlled Trials as Topic; Risk Adjustment; Surgery, Computer-Assisted; Ticlopidine; Ultrasonography, Interventional | 2021 |
Impact of one-month DAPT followed by aspirin monotherapy in patients undergoing percutaneous coronary intervention according to clinical presentation: a post hoc analysis of the randomised One-Month DAPT trial.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Hemorrhage; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2022 |
Time of Resumption of Antiplatelet Drugs After Upper Gastrointestinal Hemorrhage.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2022 |
Effect of cocoa (
Topics: Aspirin; Cacao; Chocolate; Clopidogrel; Coronary Artery Disease; Humans; Pilot Projects; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine | 2022 |
Aspirin Dosing for Secondary Prevention of Atherosclerotic Cardiovascular Disease in Patients Treated With P2Y12 Inhibitors.
Topics: Acute Coronary Syndrome; Aspirin; Atherosclerosis; Cardiovascular Diseases; Clopidogrel; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Secondary Prevention; Ticlopidine | 2023 |
2532 other study(ies) available for ticlopidine and aspirin
| Article | Year |
|---|---|
Syntheses and platelet aggregation inhibitory and antithrombotic properties of [2-[(omega-aminoalkoxy)phenyl]ethyl]benzenes.
Topics: Animals; Collagen; Fibrinolytic Agents; Mice; Platelet Aggregation Inhibitors; Rabbits; Serotonin Antagonists; Succinates | 1990 |
Synthesis, platelet aggregation inhibitory activity, and in vivo antithrombotic activity of new 1,4-dihydropyridines.
Topics: Animals; Cats; Collagen; Dihydropyridines; Humans; Kinetics; Male; Mice; Nitrendipine; Platelet Aggregation; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Thrombosis | 1988 |
Novel arylpyrazino[2,3-c][1,2,6]thiadiazine 2,2-dioxides as inhibitors of platelet aggregation. 1. Synthesis and pharmacological evaluation.
Topics: Animals; Cyclic S-Oxides; Humans; In Vitro Techniques; Male; Platelet Aggregation Inhibitors; Rabbits; Rats; Rats, Wistar; Structure-Activity Relationship; Thiadiazines | 1999 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Synthesis of 2H-benzo[b][1,4]oxazin-3(4H)-one derivatives as platelet aggregation inhibitors.
Topics: Antineoplastic Agents; Aspirin; Benzoxazines; Chemistry, Pharmaceutical; Drug Design; Glycoproteins; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Platelet Aggregation; Platelet Aggregation Inhibitors; Structure-Activity Relationship; Ticlopidine | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
The synthesis of 4,7-disubstituted-2H-benzo[b][1,4]-oxazin-3(4H)-ones using Smiles rearrangement and their in vitro evaluation as platelet aggregation inhibitors.
Topics: Benzoxazines; Binding Sites; Catalytic Domain; Molecular Docking Simulation; Piperazines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Structure-Activity Relationship | 2014 |
Novel hybrids of 3-n-butylphthalide and edaravone: Design, synthesis and evaluations as potential anti-ischemic stroke agents.
Topics: Animals; Antipyrine; Benzofurans; Cell Line; Drug Design; Edaravone; Free Radical Scavengers; Humans; Hydrogen Peroxide; Neurons; Neuroprotective Agents; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Stroke | 2015 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Aspirin-ticlopidin in Kasabach-Merritt syndrome.
Topics: Aspirin; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Hemangioma; Humans; Infant; Thrombocytopenia; Ticlopidine | 1992 |
[Kasabach-Merritt syndrome in children].
Topics: Aspirin; Child, Preschool; Disseminated Intravascular Coagulation; Embolization, Therapeutic; Hemangioma; Humans; Infant; Pediatrics; Pentoxifylline; Prednisone; Radiotherapy; Syndrome; Thrombocytopenia; Ticlopidine | 1992 |
Antithrombotic effect of ticlopidine on He-Ne laser-induced thrombus formation in rat mesenteric microvessels.
Topics: Animals; Aspirin; Blood Cell Count; Blood Coagulation Tests; Helium; Humans; Lasers; Male; Mesentery; Microcirculation; Neon; Platelet Aggregation; Rats; Rats, Wistar; Thrombosis; Ticlopidine | 1992 |
Comparative arterial antithrombotic activity of clopidogrel and acetyl salicylic acid in the pig.
Topics: Animals; Aspirin; Bleeding Time; Clopidogrel; Disease Models, Animal; Female; Femoral Artery; Fibrinolytic Agents; Male; Platelet Aggregation; Swine; Thrombosis; Ticlopidine | 1992 |
Ticlopidine for the prevention of thromboembolic stroke.
Topics: Aspirin; Cerebrovascular Disorders; Humans; Thromboembolism; Ticlopidine | 1992 |
[Strategies for antiplatelet therapy-drug-fixed method and suppression-fixed method].
Topics: Aspirin; Cerebral Infarction; Dipyridamole; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Aggregation; Recurrence; Sulfinpyrazone; Ticlopidine | 1992 |
[Antiplatelet therapy in cardiac diseases].
Topics: Angioplasty, Balloon, Coronary; Aspirin; Coronary Artery Bypass; Humans; Mitral Valve Prolapse; Myocardial Infarction; Platelet Aggregation Inhibitors; Sulfinpyrazone; Ticlopidine | 1992 |
Ticlopidine for prevention of stroke.
Topics: Aspirin; Clinical Trials as Topic; Humans; Intracranial Embolism and Thrombosis; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine | 1992 |
[Drug treatment of ischemic disturbances of circulation in the brain].
Topics: Aspirin; Brain Ischemia; Dipyridamole; Humans; Ticlopidine | 1990 |
Prevention of stroke with ticlopidine: who benefits most? TASS Baseline and Angiographic Data Subgroup.
Topics: Aspirin; Carotid Artery Diseases; Cerebral Angiography; Cerebrovascular Disorders; Female; Humans; Life Tables; Male; Prognosis; Ticlopidine | 1992 |
Effects of combination therapy with low-dose aspirin and warfarin on platelet functions after heart valve replacement.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Aspirin; Bleeding Time; Blood Platelets; Calcium; Collagen; Drug Therapy, Combination; Female; Heart Valve Prosthesis; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Prostaglandin Endoperoxides, Synthetic; Thromboembolism; Ticlopidine; Warfarin | 1991 |
Protective effects of the novel thromboxane A2 receptor antagonist sodium (E)-11-[2-(5,6-dimethyl-1-benzimidazolyl)-ethylidene]-6,11- dihydrodibenz[b,e]oxepine-2-carboxylate monohydrate against 9,11-dideoxy- 9 alpha, 11 alpha-epoxymethano-prostaglandin F2
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aspirin; Benzimidazoles; Benzoxepins; Blood Pressure; Death, Sudden; Dose-Response Relationship, Drug; Guinea Pigs; Male; Phenylacetates; Platelet Aggregation Inhibitors; Platelet Count; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Inbred Strains; Sulfonamides; Thromboxane A2; Thromboxanes; Ticlopidine | 1991 |
[Arterioarterial shunt coated with collagen. A model of acute arterial thrombosis for testing antithrombotic agents in rats].
Topics: Animals; Aspirin; Carotid Arteries; Clopidogrel; Collagen; Disease Models, Animal; Fistula; Graft Occlusion, Vascular; Male; Models, Biological; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Thrombolytic Therapy; Thrombosis; Ticlopidine | 1991 |
Benefit/risk profile of combined antiplatelet therapy with ticlopidine and aspirin.
Topics: Aged; Aspirin; Bleeding Time; Drug Synergism; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Thromboxane B2; Ticlopidine | 1991 |
[Recurrent thromboembolism due to increased acetylsalicylic acid-resistant platelet aggregation].
Topics: Aspirin; Fibrin; Humans; Male; Middle Aged; Platelet Aggregation; Recurrence; Thromboembolism; Ticlopidine | 1991 |
[Clinical evaluation of platelet antagonists on the ex vivo inhibitory effects of platelet aggregation].
Topics: Adenosine Diphosphate; Aspirin; Collagen; Dose-Response Relationship, Drug; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 1991 |
Effect of the combination of antiplatelet agents in man: combination of aspirin, trapidil, ticlopidine and dipyridamole.
Topics: Aspirin; Dipyridamole; Drug Therapy, Combination; Humans; In Vitro Techniques; Platelet Aggregation Inhibitors; Ticlopidine; Trapidil | 1990 |
Proaggregatory effect of epinephrine on rabbit platelets inhibited by ticlopidine.
Topics: Adenosine Diphosphate; Amiloride; Animals; Aspirin; Drug Interactions; Epinephrine; Hydrogen-Ion Concentration; Male; Methylamines; Monensin; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Receptors, Adrenergic, alpha; Sodium; Thromboxane A2; Ticlopidine | 1990 |
[Ticlopidine Aspirin Stroke Study].
Topics: Aspirin; Cerebrovascular Disorders; Humans; Ticlopidine | 1990 |
Comparison of ticlopidine and aspirin for the prevention of stroke.
Topics: Aspirin; Cerebrovascular Disorders; Cholesterol; Humans; Myocardial Infarction; Research Design; Ticlopidine | 1990 |
Combination therapy with low-dose aspirin and ticlopidine in cerebral ischemia.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Aged, 80 and over; Aspirin; beta-Thromboglobulin; Blood Platelets; Brain Ischemia; Cell Survival; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 1989 |
Aspirin, ticlopidine, and stroke.
Topics: Aspirin; Cerebrovascular Disorders; Humans; Ticlopidine | 1989 |
[Antiplatelet effects of combined therapy with ticlopidine and low doses of aspirin on patients with ischemic cardiopathy].
Topics: Aged; Angina Pectoris; Aspirin; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 1989 |
[Biostatistics, cosmetics and clinical research: a time for reflection?].
Topics: Aspirin; Biometry; Blood Platelets; Drug Interactions; Humans; Ticlopidine | 1989 |
[Antiplatelet effects of combination therapy with low-dose aspirin and ticlopidine in cerebral ischemia].
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Brain Ischemia; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine | 1989 |
Clinical application of a new in vitro bleeding time device on surgical patients.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aspirin; Bleeding Time; Epoprostenol; Hemorrhage; Hemostasis; Humans; Liver Cirrhosis; Platelet Aggregation Inhibitors; Platelet Function Tests; Postoperative Complications; Quinazolines; Skin; Thrombocytopenia; Ticlopidine | 1988 |
Large trial finds ticlopidine superior to aspirin in preventing stroke.
Topics: Aspirin; Cerebrovascular Disorders; Female; Follow-Up Studies; Humans; Male; Neutropenia; Random Allocation; Ticlopidine | 1989 |
Comparison of the effects of acylpyrin, curantyl and ticlid on some platelet functions in patients with polycythemia vera.
Topics: Adult; Aged; Aspirin; Blood Platelets; Dipyridamole; Female; Humans; Male; Middle Aged; Platelet Aggregation; Polycythemia Vera; Ticlopidine | 1985 |
[Advantages and shortcomings of platelet antiaggregants in the treatment of myocardial infarction].
Topics: Aged; Aspirin; Drug Eruptions; Humans; Middle Aged; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 1988 |
Comparison of the inhibitory effects of aspirin and ticlopidine on platelet aggregation and Ca2+ mobilization in rat platelets.
Topics: Animals; Anticoagulants; Aspirin; Blood Platelets; Calcium; Cyclic AMP; Female; Male; Malondialdehyde; Platelet Aggregation; Rats; Rats, Inbred Strains; Sex Factors; Thromboxane A2; Ticlopidine | 1986 |
Combined arachidonic acid and ADP platelet inhibition maximizes patency of small-diameter vascular grafts.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Vessel Prosthesis; Carotid Arteries; Dogs; Femoral Artery; Platelet Aggregation; Polytetrafluoroethylene; Thromboxane B2; Ticlopidine; Vascular Patency | 1988 |
[Current topics of anticoagulant therapy and antiplatelet therapy after cardiac valve replacement].
Topics: Adolescent; Adult; Aspirin; Drug Evaluation; Female; Heart Valve Prosthesis; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Protein C; Thromboembolism; Ticlopidine; Warfarin | 1988 |
[Anti-aggregation therapy of patients with ischemic heart disease].
Topics: Aspirin; Coronary Disease; Dipyridamole; Drug Evaluation; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Sulfinpyrazone; Ticlopidine | 1988 |
Role of adhesive proteins in platelet tumor interaction in vitro and metastasis formation in vivo.
Topics: Animals; Antibodies, Monoclonal; Aspirin; Blood Platelets; Humans; Immunologic Techniques; Lung Neoplasms; Mice; Neoplasm Metastasis; Neoplasms, Experimental; Platelet Adhesiveness; Ticlopidine; von Willebrand Factor | 1988 |
[Role of platelet anti-aggregants in cardiovascular surgery].
Topics: Aspirin; Coronary Artery Bypass; Dipyridamole; Graft Occlusion, Vascular; Humans; Platelet Aggregation; Sulfinpyrazone; Ticlopidine | 1987 |
Hemostatic effects of microfibrillar collagen hemostat (MCH) in experimental coagulopathy model and its mechanism of hemostasis.
Topics: Animals; Aspirin; Blood Coagulation Disorders; Cattle; Collagen; Dogs; Hemorrhage; Hemostatic Techniques; Hemostatics; Heparin; Spleen; Thiophenes; Thrombocytopenia; Ticlopidine; Warfarin | 1986 |
Antithrombotic effect of TRK-100, a novel, stable PGI2 analogue.
Topics: Animals; Aspirin; Collagen; Epoprostenol; Fibrinolytic Agents; In Vitro Techniques; Male; Platelet Adhesiveness; Rats; Rats, Inbred Strains; Ticlopidine | 1987 |
Platelet aggregation behaviour in patients treated with ticlopidine.
Topics: Adult; Aged; Aspirin; Atrial Fibrillation; Bleeding Time; Dipyridamole; Female; Humans; Male; Middle Aged; Platelet Adhesiveness; Platelet Aggregation; Thromboembolism; Ticlopidine | 1987 |
Validation of cognitive and functional assessment instruments in vascular dementia.
Topics: Aged; Aged, 80 and over; Aspirin; Brain Ischemia; Dementia; Double-Blind Method; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Ticlopidine | 1987 |
[Mode of action and clinical evaluation of platelet aggregation inhibitors].
Topics: Aspirin; Cerebrovascular Disorders; Dipyridamole; Graft Occlusion, Vascular; Humans; Ketanserin; Myocardial Infarction; Platelet Aggregation; Sulfinpyrazone; Ticlopidine | 1987 |
Ticlopidine versus aspirin and dipyridamole: influence on platelet deposition and three-month patency of polytetrafluoroethylene grafts.
Topics: Animals; Anticoagulants; Aspirin; Blood Vessel Prosthesis; Dipyridamole; Dogs; Female; Femoral Artery; Graft Occlusion, Vascular; Indium; Male; Platelet Aggregation; Polytetrafluoroethylene; Radioisotopes; Thiophenes; Ticlopidine | 1986 |
Adenosine diphosphate (ADP)-induced alpha-granules release from platelets of native whole blood is reduced by ticlopidine but not by aspirin or dipyridamole.
Topics: Adenosine Diphosphate; Adult; Aspirin; Blood Platelets; Cytoplasmic Granules; Dipyridamole; Female; Humans; Kinetics; Male; Ticlopidine | 1986 |
[Prevention and medical treatment of polyregional vascular lesions].
Topics: Adult; Anticoagulants; Arterial Occlusive Diseases; Arteriosclerosis; Aspirin; Diet; Dipyridamole; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Risk; Sulfinpyrazone; Thiophenes; Thrombosis; Ticlopidine | 1985 |
[Activity of ticlopidine and lysine acetylsalicylate in experimental atheromatosis. Effects on the production of PGI2].
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Arteriosclerosis; Aspirin; Diet, Atherogenic; Epoprostenol; Lysine; Male; Platelet Aggregation; Rabbits; Thiophenes; Ticlopidine | 1985 |
Antiplatelet aggregators inhibit development of stress ulcers in Sprague-Dawley rats.
Topics: Animals; Anticoagulants; Aspirin; Capillaries; Dipyridamole; Gastric Mucosa; Male; Platelet Aggregation; Pyridines; Rats; Rats, Inbred Strains; Stomach Ulcer; Stress, Physiological; Sulfinpyrazone; Thiophenes; Thrombosis; Ticlopidine | 1985 |
Antithrombotic effect of ticlopidine in a platelet-independent model of venous thrombosis.
Topics: Animals; Aspirin; Blood Platelets; Fibrinolytic Agents; Male; Rats; Rats, Inbred Strains; Thiophenes; Thrombophlebitis; Ticlopidine | 1985 |
Laser-induced thrombi in rat mesenteric vessels and antithrombotic drugs.
Topics: Animals; Aspirin; Blood Platelets; Dipyridamole; Disease Models, Animal; Fibrinolytic Agents; Heparin; Lasers; Male; Mesenteric Arteries; Mesenteric Vascular Occlusion; Molsidomine; Oxazoles; Platelet Aggregation; Propionates; Pyrazoles; Pyrazolones; Rats; Rats, Inbred Strains; Sydnones; Thiophenes; Thrombosis; Ticlopidine | 1983 |
The thrombogenicity of Dacron arterial grafts and its modification by platelet inhibitory drugs.
Topics: Arteries; Aspirin; Blood Platelets; Blood Vessel Prosthesis; Dipyridamole; Drug Therapy, Combination; Humans; Microscopy, Electron; Platelet Adhesiveness; Platelet Aggregation; Polyethylene Terephthalates; Sulfinpyrazone; Thiophenes; Thrombosis; Ticlopidine | 1984 |
[The effect of ticlopidine and lysine acetylsalicylate on fibrinolytic activity of the arterial wall in experimental atherosclerosis].
Topics: Animals; Arteriosclerosis; Aspirin; Fibrinolysis; Lysine; Male; Muscle, Smooth, Vascular; Rabbits; Thiophenes; Ticlopidine | 1984 |
Inhibition of thrombocytopenic episodes caused by the Arthus reaction, the sub-lethal Forssman reaction and ADP.
Topics: Adenosine Diphosphate; Animals; Antibodies; Arthus Reaction; Aspirin; Dipyridamole; Forssman Antigen; Guinea Pigs; Humans; Nervous System Diseases; Platelet Count; Pyridines; Sulfides; Sulfinpyrazone; Thiophenes; Thrombocytopenia; Ticlopidine | 1980 |
Effects of various antiplatelet drugs and defibrinating agent on experimental glomerulonephritis in rats.
Topics: Animals; Anticoagulants; Aspirin; Batroxobin; Blood Platelets; Dipyridamole; Glomerulonephritis; Immune Complex Diseases; Kidney; Nephritis; Proteinuria; Pyridines; Rats; Rats, Inbred Strains; Thiophenes; Ticlopidine | 1982 |
In vivo study of platelet aggregation in rats.
Topics: Adenosine Diphosphate; Animals; Aspirin; Collagen; Diet; Dose-Response Relationship, Drug; Male; Methods; Platelet Aggregation; Platelet Count; Rats; Rats, Inbred Strains; Thiophenes; Thrombosis; Ticlopidine | 1984 |
Ex vivo and in vivo evaluation of drugs that inhibit platelet function.
Topics: Adenosine Diphosphate; Animals; Aspirin; Bleeding Time; Blood Platelets; Collagen; Dipyridamole; Imidazoles; Male; Papio; Platelet Aggregation; Sulfinpyrazone; Thiazines; Thiophenes; Ticlopidine | 1983 |
Ticlopidine: quo vadis? Adverse reactions in man.
Topics: Anticoagulants; Aspirin; Diarrhea; Humans; Neutropenia; Product Surveillance, Postmarketing; Thiophenes; Ticlopidine | 1984 |
Thrombotic etiology of stress ulcers. 1. The effect of anticoagulant and antiplatelet aggregators in the development of stress ulcers in rats.
Topics: Animals; Anticoagulants; Aspirin; Dipyridamole; Gastric Acidity Determination; Gastric Mucosa; Heparin; Male; Peptic Ulcer Hemorrhage; Platelet Aggregation; Platelet Count; Rats; Rats, Inbred Strains; Stomach Ulcer; Stress, Physiological; Thiophenes; Thrombosis; Ticlopidine | 1983 |
Effects of ticlopidine and aspirin on endotoxin-induced disseminated intravascular coagulation in rats.
Topics: Animals; Aspirin; Disseminated Intravascular Coagulation; Rats; Thiophenes; Ticlopidine | 1983 |
[Platelet antiaggregants and bleeding time lengthening: management in the preoperative period].
Topics: Adrenal Cortex Hormones; Aspirin; Blood Coagulation; Humans; Platelet Aggregation; Preoperative Care; Thiophenes; Ticlopidine | 1983 |
Antiplatelet drugs and thrombosis prevention: ticlopidine in perspective.
Topics: Adenosine Diphosphate; Aspirin; Bleeding Time; Blood Platelets; Fibrinolytic Agents; Humans; Thiophenes; Thrombosis; Ticlopidine | 1984 |
Platelet aggregation measured in rabbit whole blood: in vitro study of 3 aggregating agents and ex vivo inhibition by aspirin and ticlopidine.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; In Vitro Techniques; Platelet Aggregation; Platelet Count; Rabbits; Thiophenes; Ticlopidine | 1982 |
Study of platelet aggregation induced by platelet activating factor (PAF) after administration of ticlopidine or aspirin.
Topics: Adult; Aged; Anticoagulants; Aspirin; Epinephrine; Humans; In Vitro Techniques; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Thiophenes; Ticlopidine | 1983 |
Effects of ticlopidine and aspirin on endotoxin-induced disseminated intravascular coagulation in rats.
Topics: Animals; Aspirin; Disease Models, Animal; Disseminated Intravascular Coagulation; Endotoxins; Female; Fibrin Fibrinogen Degradation Products; Fibrinogen; Kidney Glomerulus; Partial Thromboplastin Time; Platelet Count; Prothrombin Time; Rats; Rats, Inbred Strains; Thiophenes; Ticlopidine | 1983 |
Modulation of the inhibitory action of prostaglandin E1 on platelet aggregation in rats: a study with ticlopidine, aspirin, dipyridamole and sulfinpyrazone.
Topics: Adenosine Diphosphate; Alprostadil; Animals; Aspirin; Dipyridamole; Male; Phosphorylation; Platelet Aggregation; Prostaglandins E; Rats; Rats, Inbred Strains; Sulfinpyrazone; Thiophenes; Ticlopidine | 1982 |
Antithrombotic effects of ticlopidine, acetylsalicyclic acid and dipyridamole in vascular shunt model in rats.
Topics: Animals; Arteriovenous Shunt, Surgical; Aspirin; Blood Coagulation; Blood Coagulation Tests; Dipyridamole; Fibrinogen; Fibrinolytic Agents; Hematocrit; Male; Platelet Aggregation; Platelet Count; Pyridines; Rats; Serum Globulins; Thiophenes; Ticlopidine | 1980 |
Effect of ticlopidine on human platelet responsiveness ex vivo: comparison with aspirin.
Topics: Adenosine Diphosphate; Adult; Aspirin; Collagen; Dose-Response Relationship, Drug; Epinephrine; Female; Humans; Male; Middle Aged; Platelet Aggregation; Pyridines; Serotonin; Thiophenes; Ticlopidine | 1980 |
Beneficial effect of CV-4151 (Isbogrel), a thromboxane A2 synthase inhibitor, in a rat middle cerebral artery thrombosis model.
Topics: Animals; Aspirin; Brain Chemistry; Brain Edema; Cerebral Arteries; Cerebral Infarction; Drug Evaluation, Preclinical; Fatty Acids, Monounsaturated; Fibrinolytic Agents; Guinea Pigs; Intracranial Embolism and Thrombosis; Lactates; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Methacrylates; Photochemistry; Potassium; Pyridines; Rabbits; Rats; Rats, Sprague-Dawley; Rose Bengal; Sodium; Thromboxane A2; Ticlopidine | 1995 |
Anti-thrombotic activity of KBT-3022 in experimental models of thrombosis.
Topics: Animals; Arachidonic Acid; Aspirin; Cyclooxygenase Inhibitors; Extracorporeal Circulation; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Mice; Mice, Inbred Strains; Platelet Aggregation Inhibitors; Pyrroles; Rabbits; Silver Nitrate; Thiazoles; Thrombosis; Ticlopidine | 1995 |
ACP guideline on drug therapy for stroke prevention.
Topics: Aspirin; Cerebrovascular Disorders; Humans; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Societies, Medical; Ticlopidine; United States; Warfarin | 1995 |
Pharmacological prophylaxis against postoperative graft occlusion after peripheral vascular surgery: a world-wide survey.
Topics: Anticoagulants; Aspirin; Data Collection; Dipyridamole; Drug Utilization; Graft Occlusion, Vascular; Humans; Peripheral Vascular Diseases; Practice Patterns, Physicians'; Societies, Medical; Ticlopidine; Time Factors; Vascular Surgical Procedures | 1995 |
[Stent after-care: new approaches to coagulation inhibiting therapy].
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Blood Coagulation Tests; Coronary Disease; Drug Therapy, Combination; Graft Occlusion, Vascular; Heparin; Humans; Stents; Ticlopidine | 1995 |
New no-donors with antithrombotic and vasodilating activities, X: Antiplatelet and antithrombotic effects of 3-methylsydnone-5-nitrosimine (RE 2047) in combination with ASA, pentoxifylline, and ticlopidine.
Topics: Animals; Aspirin; Drug Synergism; Fibrinolytic Agents; Pentoxifylline; Platelet Aggregation Inhibitors; Rats; Sydnones; Ticlopidine | 1995 |
Essential thrombocytemia and ischemic stroke: report of six cases.
Topics: Aged; Aspirin; Brain Ischemia; Cerebrovascular Disorders; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Platelet Count; Thrombocytosis; Ticlopidine; Tomography, X-Ray Computed | 1994 |
The effects of KBT-3022, a new anti-platelet agent, on hemorheological properties in guinea pigs.
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Animals; Aspirin; Blood Viscosity; Diphosphoglyceric Acids; Drug Evaluation, Preclinical; Erythrocyte Deformability; Fibrinogen; Guinea Pigs; Hematocrit; Hemorheology; Pentoxifylline; Plasma; Platelet Aggregation Inhibitors; Pyrroles; Thiazoles; Ticlopidine | 1995 |
Axial dependence of collagen-induced thrombus formation in flowing non-anticoagulated human blood. Anti-platelet drugs impair thrombus growth and increase platelet-collagen adhesion.
Topics: Aspirin; Blood Coagulation; Clopidogrel; Collagen; Fibrin; Hemorheology; Humans; Male; Perfusion; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Smoking; Stress, Mechanical; Surface Properties; Ticlopidine | 1995 |
The antithrombotic effects of ticlopidine and aspirin in a microvascular thrombogenic model.
Topics: Administration, Oral; Animals; Aspirin; Femoral Artery; Graft Occlusion, Vascular; Male; Microsurgery; Rabbits; Thrombosis; Ticlopidine; Vascular Patency | 1995 |
Effects of thromboxane A2 synthase inhibitors (CV-4151 and ozagrel), aspirin, and ticlopidine on the thrombosis caused by endothelial cell injury.
Topics: Animals; Aspirin; Bleeding Time; Endothelium, Vascular; Fatty Acids, Monounsaturated; Femoral Vein; Male; Methacrylates; Platelet Aggregation; Pyridines; Rats; Rats, Sprague-Dawley; Thrombosis; Thromboxane-A Synthase; Thromboxanes; Ticlopidine | 1995 |
Stroking the stroke prevention numbers.
Topics: Aspirin; Cerebrovascular Disorders; Female; Humans; Male; Risk; Ticlopidine | 1995 |
[Is ticlopidine hydrochloride preferred in prevention of thrombotic cerebral infarct over acetylsalicylic acid?].
Topics: Aspirin; Dose-Response Relationship, Drug; Humans; Intracranial Embolism and Thrombosis; Ticlopidine | 1994 |
Antithrombotic effects of KW-3635, a thromboxane A2-receptor antagonist, in guinea pigs.
Topics: Animals; Arterial Occlusive Diseases; Aspirin; Benzimidazoles; Benzoxepins; Blood Coagulation; Blood Platelets; Disease Models, Animal; Erythrocyte Count; Femoral Artery; Guinea Pigs; Lauric Acids; Male; Phenylacetates; Platelet Count; Sulfonamides; Thrombosis; Thromboxane A2; Thromboxanes; Ticlopidine | 1994 |
Inhibitory effect of clentiazem (TA-3090) on platelet aggregation--alone and in combination with aspirin or ticlopidine.
Topics: Animals; Aspirin; Calcium Channel Blockers; Diltiazem; Drug Synergism; Drug Therapy, Combination; Humans; Male; Molecular Structure; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Ticlopidine | 1994 |
Relative benefits of ticlopidine and aspirin.
Topics: Aspirin; Cerebrovascular Disorders; Humans; Randomized Controlled Trials as Topic; Ticlopidine | 1994 |
[Thrombocyte function inhibitors in stroke prevention. Ticlopidine as an alternative to acetylsalicylic acid].
Topics: Aspirin; Cerebral Infarction; Humans; Intracranial Embolism and Thrombosis; Platelet Aggregation; Randomized Controlled Trials as Topic; Ticlopidine | 1994 |
Prevention of intra-coronary thrombosis in the anaesthetised dog: the importance of thromboxane A2 and thrombin.
Topics: Anesthesia; Animals; Aspirin; Biphenyl Compounds; Blood Coagulation Tests; Coronary Circulation; Coronary Thrombosis; Dogs; Drug Synergism; Drug Therapy, Combination; Electric Stimulation; Female; Fibrinolytic Agents; Heptanoic Acids; Hirudin Therapy; Hirudins; Male; Platelet Aggregation; Recombinant Proteins; Thrombin; Thromboxane A2; Ticlopidine | 1994 |
Clopidogrel is more effective than aspirin in preventing coronary artery reocclusion after thrombolysis.
Topics: Animals; Aspirin; Blood Coagulation; Clopidogrel; Coronary Thrombosis; Disease Models, Animal; Dogs; Drug Therapy, Combination; Hematocrit; Heparin; In Vitro Techniques; Platelet Aggregation; Platelet Aggregation Inhibitors; Recurrence; Thrombolytic Therapy; Ticlopidine; Tissue Plasminogen Activator | 1993 |
Clopidogrel is more effective than aspirin as adjuvant treatment to prevent reocclusion after thrombolysis.
Topics: Animals; Aspirin; Clopidogrel; Coronary Thrombosis; Dogs; Drug Therapy, Combination; Fibrinolytic Agents; Platelet Aggregation Inhibitors; Recurrence; Ticlopidine | 1994 |
Effect of various drugs on adriamycin-enhanced venous thrombosis in the rat: importance of PAF.
Topics: Animals; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Doxorubicin; Leukocyte Count; Male; Platelet Activating Factor; Platelet Count; Rats; Rats, Sprague-Dawley; Thiazoles; Thrombophlebitis; Ticlopidine | 1994 |
Effect of plasma fibrinogen concentration on the inhibition of platelet aggregation after ticlopidine compared with aspirin.
Topics: Adenosine Diphosphate; Aged; Aspirin; Cerebral Infarction; Cerebrovascular Disorders; Collagen; Female; Fibrinogen; Humans; Male; Platelet Aggregation; Platelet Count; Ticlopidine | 1994 |
Effect of various antiplatelet agents on acute arterial thrombosis in the rat.
Topics: Acute Disease; Amino Acid Sequence; Animals; Aspirin; Carotid Artery Thrombosis; Clopidogrel; Electric Stimulation; Hirudin Therapy; Male; Molecular Sequence Data; Oligopeptides; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Thiazoles; Thrombolytic Therapy; Thromboxane-A Synthase; Ticlopidine | 1993 |
Ticlopidine hydrochloride use and threatened stroke.
Topics: Aspirin; Cerebrovascular Disorders; Humans; Ticlopidine | 1994 |
Does ticlopidine prevent reversible cerebrovascular ischemic events in women?
Topics: Aspirin; Female; Humans; Ischemic Attack, Transient; Ticlopidine | 1994 |
Effect of aspirin and clopidogrel on platelet-dependent tissue factor expression in endothelial cells.
Topics: Adenosine Diphosphate; Animals; Aorta; Aspirin; Blood Platelets; Cattle; Clopidogrel; Endothelium, Vascular; Female; Ligation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Thionucleotides; Thrombin; Thromboplastin; Thrombosis; Ticlopidine; Vena Cava, Inferior | 1994 |
Guidelines for medical treatment for stroke prevention. American College of Physicians.
Topics: Aspirin; Atrial Fibrillation; Cerebrovascular Disorders; Humans; Ischemic Attack, Transient; Myocardial Infarction; Recurrence; Risk Factors; Ticlopidine; Warfarin | 1994 |
Correlation between bleeding time and antithrombotic effect of platelet-suppressive agents in rat experimental model.
Topics: Animals; Aspirin; Bleeding Time; Carotid Artery Thrombosis; Disease Models, Animal; Male; Platelet Aggregation; Rats; Rats, Wistar; Ticlopidine | 1994 |
Ticlopidine, trials, and torture.
Topics: Arterial Occlusive Diseases; Aspirin; Cause of Death; Cerebrovascular Disorders; Clinical Trials as Topic; Humans; Risk Factors; Ticlopidine; Treatment Outcome | 1994 |
Cost-effectiveness of ticlopidine in preventing stroke in high-risk patients.
Topics: Aged; Aspirin; Cerebrovascular Disorders; Cohort Studies; Cost-Benefit Analysis; Decision Support Techniques; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Health Care Costs; Humans; Incidence; Ischemic Attack, Transient; Life Expectancy; Male; Neutropenia; Quality of Life; Risk Factors; Survival Rate; Ticlopidine | 1994 |
Ticlopidine hydrochloride and prevention of stroke.
Topics: Aspirin; Cerebrovascular Disorders; Clinical Trials as Topic; Female; Humans; Ischemic Attack, Transient; Male; Risk Factors; Ticlopidine | 1993 |
[A comparison of the gastroduodenal tolerance of ticlopidine and acetylsalicylic acid].
Topics: Aspirin; Drug Tolerance; Duodenum; Humans; Stomach; Ticlopidine | 1993 |
Effects of antithrombotic drugs in a rat model of aspirin-insensitive arterial thrombosis.
Topics: Amino Acid Chloromethyl Ketones; Animals; Aspirin; Azepines; Bridged Bicyclo Compounds, Heterocyclic; Carotid Artery Thrombosis; Dipyridamole; Fibrinolytic Agents; Heparin; Male; Oxazoles; Propionates; Rats; Rats, Sprague-Dawley; Thrombolytic Therapy; Ticlopidine; Triazoles; Warfarin | 1993 |
Experimental thrombosis on a collagen coated arterioarterial shunt in rats: a pharmacological model to study antithrombotic agents inhibiting thrombin formation and platelet deposition.
Topics: Animals; Anticoagulants; Arterio-Arterial Fistula; Aspirin; Carotid Artery Thrombosis; Clopidogrel; Collagen; Disease Models, Animal; Drug Evaluation, Preclinical; Fibrin; Fibrinogen; Fibrinolytic Agents; Glass; Heparin; Hirudin Therapy; Hirudins; Male; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Polyethylenes; Rats; Rats, Wistar; Recombinant Proteins; Regional Blood Flow; Silicones; Thrombin; Ticlopidine | 1993 |
Effect of Y-20811, a thromboxane synthetase inhibitor, on photochemically induced cerebral embolism in rabbits.
Topics: Animals; Aspirin; Carotid Artery Thrombosis; Carotid Stenosis; Cerebral Infarction; Disease Models, Animal; Imidazoles; Intracranial Embolism and Thrombosis; Ligation; Male; Photochemistry; Platelet Aggregation; Rabbits; Rose Bengal; Thromboxane-A Synthase; Ticlopidine | 1993 |
Ticlopidine and stroke prevention.
Topics: Aspirin; Cerebrovascular Disorders; Clinical Trials as Topic; Cost-Benefit Analysis; Humans; Ticlopidine | 1993 |
Ischemic stroke, Part 2: Optimal treatment and prevention.
Topics: Aged; Aspirin; Brain Edema; Brain Ischemia; Cerebral Infarction; Heparin; Humans; Recurrence; Risk Factors; Ticlopidine; Warfarin | 1993 |
Is aspirin effective in preventing strokes in diabetic patients?
Topics: Aspirin; Cerebrovascular Disorders; Diabetes Complications; Humans; Ticlopidine | 1993 |
Coagulation-fibrinolysis system in poststroke patients receiving antiplatelet medication.
Topics: Aged; alpha-2-Antiplasmin; Antifibrinolytic Agents; Antithrombin III; Aspirin; Blood Coagulation; Cerebrovascular Disorders; Female; Fibrinogen; Fibrinolysin; Fibrinolysis; Humans; Male; Middle Aged; Peptide Hydrolases; Plasminogen Activator Inhibitor 1; Platelet Aggregation; Ticlopidine; Tissue Plasminogen Activator | 1993 |
Antithrombotic effect of TA-993, a novel 1,5-benzothiazepine derivative, in conscious rats.
Topics: Administration, Oral; Animals; Antithrombins; Aspirin; Diltiazem; Dose-Response Relationship, Drug; Embolism; Male; Microscopy, Electron; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Thrombosis; Ticlopidine; Time Factors | 1995 |
Platelet activation and thrombosis: studies in a patient with essential thrombocythemia.
Topics: Adenosine Diphosphate; Adult; Antibodies, Monoclonal; Aspirin; Blood Platelets; Disease Susceptibility; Female; Fibrinogen; Flow Cytometry; Humans; Mesenteric Arteries; Mesenteric Vascular Occlusion; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Portal Vein; Receptors, Purinergic P2; Splenic Vein; Thrombocythemia, Essential; Thrombosis; Ticlopidine | 1996 |
Antithrombotic effects of TAK-029, a novel GPIIb/IIIa antagonist, in guinea pigs: comparative studies with ticlopidine, clopidogrel, aspirin, prostaglandin E1 and argatroban.
Topics: Alprostadil; Animals; Arginine; Aspirin; Clopidogrel; Dogs; Fibrinolytic Agents; Guanidines; Guinea Pigs; Humans; Macaca fascicularis; Male; Pipecolic Acids; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrazines; Sulfonamides; Ticlopidine | 1996 |
Management of intracranial hemorrhage associated with anticoagulant therapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Cerebral Hemorrhage; Child; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Ticlopidine; Tomography, X-Ray Computed; Warfarin | 1995 |
Inhibitory effects of TA-993, a new 1,5-benzothiazepine derivative, on platelet aggregation.
Topics: Animals; Aspirin; Basilar Artery; Calcium; Diltiazem; Dogs; Dose-Response Relationship, Drug; Electrophysiology; Fibrinolytic Agents; Humans; Male; Mice; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Ticlopidine; Vasoconstriction | 1996 |
In vivo evaluation of antiplatelet agents in gerbil model of carotid artery thrombosis.
Topics: Animals; Aspirin; Carotid Artery Diseases; Carotid Artery Injuries; Carotid Artery, Common; Cerebrovascular Disorders; Dipyridamole; Disease Models, Animal; Drug Evaluation, Preclinical; Endothelium, Vascular; Feasibility Studies; Gerbillinae; Injections, Intravenous; Male; Microscopy, Electron; Platelet Aggregation Inhibitors; Pyridines; Reproducibility of Results; Thrombosis; Ticlopidine | 1996 |
[Prescription of platelet antiaggregants in secondary prevention of ischemic heart disease].
Topics: Age Factors; Aged; Aged, 80 and over; Aspirin; Dipyridamole; Drug Prescriptions; Family Practice; Female; Humans; Male; Medical Audit; Medicine; Myocardial Ischemia; Platelet Aggregation Inhibitors; Prevalence; Primary Health Care; Salicylates; Spain; Specialization; Ticlopidine; Urban Population | 1996 |
Ticlopidine and renal function.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Coronary Disease; Creatinine; Drug Therapy, Combination; Humans; Kidney; Male; Middle Aged; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 1996 |
[Stroke in young people].
Topics: Adolescent; Adult; Aspirin; Brain Ischemia; Child; Dipyridamole; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prognosis; Retrospective Studies; Risk Factors; Sex Factors; Ticlopidine | 1996 |
[Antiaggregant treatment for cerebral ischemia: ticlopidine versus aspirin].
Topics: Aged; Aspirin; Brain Ischemia; Carotid Arteries; Female; Humans; Male; Platelet Aggregation Inhibitors; Retrospective Studies; Ticlopidine | 1996 |
Primary stent implantation without coumadin in acute myocardial infarction.
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Case-Control Studies; Coronary Angiography; Coronary Disease; Disease-Free Survival; Feasibility Studies; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Recurrence; Stents; Ticlopidine; Time Factors; Treatment Outcome; Warfarin | 1996 |
Platelet activation and coronary stent implantation. Effect of antithrombotic therapy.
Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Case-Control Studies; Coronary Vessels; Female; Fibrinogen; Fibrinolytic Agents; Heparin; Humans; Male; Middle Aged; P-Selectin; Phenprocoumon; Platelet Activation; Platelet Count; Platelet Glycoprotein GPIIb-IIIa Complex; Stents; Ticlopidine | 1996 |
The antiaggregating and antithrombotic activity of ticlopidine is potentiated by aspirin in the rat.
Topics: Animals; Aspirin; Bleeding Time; Cell Division; Drug Synergism; Female; Fibrinolytic Agents; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Thrombosis; Ticlopidine; Tunica Intima | 1996 |
The effect of oral antiplatelet agents on tissue plasminogen activator-mediated thrombolysis in a rabbit model of thromboembolic stroke.
Topics: Animals; Aspirin; Brain; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Intracranial Embolism and Thrombosis; Leukocyte Count; Male; Neutrophils; Platelet Aggregation Inhibitors; Platelet Count; Premedication; Rabbits; Thrombolytic Therapy; Ticlopidine; Tissue Plasminogen Activator | 1996 |
Inhibitory effects of the new anti-platelet agent KBT-3022 and its metabolite on rabbit neutrophil function in vitro.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Binding Sites; Calcium; Cell Adhesion; Cilostazol; Complement C3-C5 Convertases; Complement C5a; Cyclooxygenase Inhibitors; Indomethacin; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyrroles; Rabbits; Structure-Activity Relationship; Superoxides; Tetradecanoylphorbol Acetate; Tetrazoles; Thiazoles; Ticlopidine | 1996 |
The efficacy and potency of antiplatelet activity of ticlopidine is increased by aspirin.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Aspirin; Collagen; Drug Synergism; Female; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 1996 |
Comparison of aspirin alone versus aspirin plus ticlopidine after coronary artery stenting.
Topics: Aged; Aspirin; Coronary Disease; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Prospective Studies; Stents; Thrombosis; Ticlopidine; Treatment Outcome | 1996 |
Combined ticlopidine and aspirin versus aspirin therapy alone after stent implantation.
Topics: Aspirin; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Postoperative Care; Stents; Thrombosis; Ticlopidine | 1996 |
Intracoronary stenting using slotted tubular stents with intravascular ultrasound and anticoagulation.
Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Combined Modality Therapy; Coronary Disease; Coronary Vessels; Drug Therapy, Combination; Equipment Design; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Stents; Ticlopidine; Treatment Outcome; Ultrasonography, Interventional | 1996 |
Intravascular ultrasound-guided emergency coronary Palmaz-Schatz stent placement without post-procedural systemic anticoagulation.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Coronary Disease; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Stents; Ticlopidine; Treatment Outcome; Ultrasonography, Interventional | 1996 |
Subacute stent thrombosis in the era of intravascular ultrasound-guided coronary stenting without anticoagulation: frequency, predictors and clinical outcome.
Topics: Anticoagulants; Aspirin; Case-Control Studies; Causality; Coronary Angiography; Coronary Disease; Coronary Thrombosis; Female; Follow-Up Studies; Humans; Incidence; Logistic Models; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Stents; Ticlopidine; Time Factors; Treatment Outcome; Ultrasonography, Interventional | 1997 |
[Oral anticoagulation in activated protein C resistance?].
Topics: Anticoagulants; Arterial Occlusive Diseases; Aspirin; Drug Resistance; Humans; Male; Middle Aged; Phenprocoumon; Platelet Aggregation Inhibitors; Protein C; Stents; Ticlopidine | 1996 |
CAPRIE trial.
Topics: Aspirin; Brain Ischemia; Clopidogrel; Humans; Myocardial Infarction; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine; Treatment Outcome | 1997 |
CAPRIE trial.
Topics: Aspirin; Brain Ischemia; Clopidogrel; Humans; Myocardial Infarction; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Research Design; Ticlopidine; Treatment Outcome | 1997 |
CAPRIE trial.
Topics: Aspirin; Brain Ischemia; Clopidogrel; Drug Costs; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine | 1997 |
CAPRIE trial.
Topics: Aspirin; Cerebrovascular Disorders; Clopidogrel; Cost-Benefit Analysis; Dipyridamole; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine; Treatment Outcome | 1997 |
Ticlopidine and aspirin interactions.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clinical Trials as Topic; Coronary Disease; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Recurrence; Ticlopidine | 1997 |
Neutropenia with ticlopidine plus aspirin.
Topics: Agranulocytosis; Aspirin; Coronary Disease; Humans; Monitoring, Physiologic; Neutropenia; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Time Factors | 1997 |
Aspirin versus clopidogrel: the wrong question?
Topics: Aspirin; Cerebrovascular Disorders; Clopidogrel; Humans; Ischemia; Myocardial Infarction; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Research Design; Ticlopidine; Treatment Outcome | 1997 |
Ticlopidine in the prevention of thrombus formation after percutaneous transluminal coronary angioplasty (PTCA).
Topics: Angioplasty, Balloon, Coronary; Aspirin; Coronary Angiography; Coronary Disease; Coronary Thrombosis; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine | 1997 |
Effects of antiplatelet drugs on dialysis-associated platelet deposition in polytetrafluoroethylene grafts.
Topics: Arteriovenous Shunt, Surgical; Aspirin; Blood Vessel Prosthesis; Humans; Indium Radioisotopes; Kidney Failure, Chronic; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Polytetrafluoroethylene; Renal Dialysis; Ticlopidine | 1997 |
Antiplatelet therapy alone is safe and effective after coronary stenting: observations of a transition in practice.
Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Coronary Artery Bypass; Coronary Disease; Coronary Thrombosis; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Radiography; Reoperation; Retrospective Studies; Stents; Ticlopidine; Treatment Outcome; Warfarin | 1997 |
Neutropenia with ticlopidine plus aspirin.
Topics: Aspirin; Chemoprevention; Coronary Thrombosis; Coronary Vessels; Drug Combinations; Fibrinolytic Agents; Humans; Neutropenia; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 1997 |
Clopidogrel: a new safe and effective antiplatelet agent. But unanswered questions remain.
Topics: Arteriosclerosis; Aspirin; Cerebrovascular Disorders; Clopidogrel; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Thrombosis; Ticlopidine | 1997 |
Antiplatelet and antithrombotic efficacy of SR 121787, a nonpeptide orally active GP IIb/IIIa antagonist, in rabbits: comparison with clopidogrel and aspirin.
Topics: Animals; Aspirin; Benzylamines; Clopidogrel; Hemodynamics; Hemostasis; Male; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Rabbits; Thiazoles; Thrombosis; Ticlopidine | 1997 |
The role of antiplatelet therapy in stroke prevention.
Topics: Aspirin; Cerebrovascular Disorders; Clinical Trials as Topic; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 1997 |
Ticlopidine-associated pancytopenia: implications of an acetylsalicylic acid alternative.
Topics: Aspirin; Cardiovascular Diseases; Drug Resistance; Fatal Outcome; Female; Humans; Middle Aged; Neutropenia; Pancytopenia; Platelet Aggregation Inhibitors; Pneumonia; Respiratory Distress Syndrome; Ticlopidine | 1997 |
New stent delivery balloon: a technical note.
Topics: Angioplasty, Balloon; Aspirin; Coronary Angiography; Coronary Disease; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Stents; Ticlopidine; Treatment Outcome | 1997 |
Antithrombotic therapy with intracoronary stenting.
Topics: Anticoagulants; Aspirin; Blood Vessel Prosthesis Implantation; Combined Modality Therapy; Coronary Disease; Drug Therapy, Combination; Humans; Stents; Thrombolytic Therapy; Ticlopidine | 1997 |
Antiplatelet therapy following stent deployment.
Topics: Aspirin; Blood Vessel Prosthesis Implantation; Combined Modality Therapy; Coronary Disease; Humans; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 1997 |
[Comparative study of 2 antithrombotic regimens in 75 patients with coronary endoprostheses].
Topics: Acenocoumarol; Adult; Aged; Anticoagulants; Aspirin; Coronary Disease; Dipyridamole; Drug Evaluation; Drug Therapy, Combination; Female; Fibrinolytic Agents; Hemorrhage; Heparin; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Retrospective Studies; Stents; Thrombosis; Ticlopidine | 1997 |
[Myocardial infarct, stroke and vascular events reduced by a third].
Topics: Aspirin; Cerebrovascular Disorders; Clopidogrel; Humans; Myocardial Infarction; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Ticlopidine | 1997 |
Reduction of monocyte-platelet interaction and monocyte activation in patients receiving antiplatelet therapy after coronary stent implantation.
Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Aspirin; Blood Platelets; Female; Flow Cytometry; Humans; Lymphocyte Activation; Male; Middle Aged; Monocytes; Phenprocoumon; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine | 1997 |
[Stroke. Earliest possible acute intervention and promising successful secondary prevention. "Newest trends in epidemiology, pathogenesis and therapy of stroke". Symposium in Dresden, 4 October 1997].
Topics: Aspirin; Cerebrovascular Disorders; Emergencies; Humans; Platelet Aggregation Inhibitors; Secondary Prevention; Ticlopidine; Time Factors | 1997 |
Blocking platelets more: are we skating on thin ice?
Topics: Abciximab; Antibodies, Monoclonal; Aspirin; Cerebrovascular Disorders; Clopidogrel; Humans; Immunoglobulin Fab Fragments; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine | 1998 |
[Acetylsalicylic acid in ischemic insult].
Topics: Anticoagulants; Aspirin; Brain Ischemia; Drug Therapy, Combination; Humans; Myocardial Infarction; Phenprocoumon; Platelet Aggregation Inhibitors; Ticlopidine | 1998 |
Frequency of adverse clinical events in the 12 months following successful intracoronary stent placement in patients treated with aspirin and ticlopidine (without warfarin).
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Confounding Factors, Epidemiologic; Coronary Disease; Coronary Vessels; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Treatment Outcome; Ultrasonography, Interventional | 1998 |
Secondary prevention of stroke--new trials.
Topics: Aged; Aspirin; Cerebrovascular Disorders; Clopidogrel; Delayed-Action Preparations; Dipyridamole; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Ticlopidine | 1998 |
[Coronary stents].
Topics: Aspirin; Belgium; Coronary Disease; Humans; Myocardial Revascularization; Platelet Aggregation Inhibitors; Recurrence; Reimbursement Mechanisms; Stents; Ticlopidine | 1998 |
Antiplatelet therapy and patency of saphenous-vein bypass grafts in the legs.
Topics: Aspirin; Graft Occlusion, Vascular; Humans; Multicenter Studies as Topic; Platelet Aggregation Inhibitors; Saphenous Vein; Ticlopidine | 1998 |
Influence of low-intensity anticoagulation and low-dose antiplatelet agent on coagulation-fibrinolysis system after mechanical prosthetic valve replacement.
Topics: Anticoagulants; Aortic Valve; Aspirin; Blood Coagulation; Blood Vessel Prosthesis; Female; Heart Valve Prosthesis Implantation; Humans; Male; Middle Aged; Mitral Valve; Platelet Aggregation Inhibitors; Postoperative Care; Ticlopidine; Time Factors; Warfarin | 1998 |
Clinical safety and efficacy of clopidogrel--implications of the Clopidogrel versus Aspirin in Patients at Risk of Ischemic Events (CAPRIE) study for future management of atherosclerotic disease.
Topics: Arteriosclerosis; Aspirin; Atrial Fibrillation; Brain Ischemia; Clopidogrel; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Ticlopidine; United States; Vascular Diseases | 1998 |
Clinical and angiographic outcome of Micro Stent II implantation in native coronary arteries.
Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Aspirin; Blood Vessel Prosthesis Implantation; Coronary Angiography; Coronary Disease; Coronary Vessels; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Prospective Studies; Recurrence; Stents; Ticlopidine; Treatment Outcome | 1998 |
[Atrial fibrillation and thromboembolism: a multicenter cooperative study. Research Group for Antiarrhythmic Drug Therapy].
Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Dipyridamole; Female; Heart Diseases; Humans; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Prevalence; Prognosis; Retrospective Studies; Risk Factors; Thromboembolism; Ticlopidine; Warfarin | 1998 |
[Secondary prevention of recurrent transient ischemic attacks].
Topics: Anticoagulants; Aspirin; Cerebral Infarction; Drug Therapy, Combination; Female; Humans; Ischemic Attack, Transient; Middle Aged; Platelet Aggregation Inhibitors; Recurrence; Ticlopidine | 1998 |
Micro stent implantation in patients with acute myocardial infarction without anticoagulation: clinical experience with two different antithrombotic protocols.
Topics: Abciximab; Antibodies, Monoclonal; Aspirin; Blood Vessel Prosthesis Implantation; Coronary Angiography; Coronary Artery Bypass; Coronary Thrombosis; Drug Therapy, Combination; Female; Fibrinolytic Agents; Follow-Up Studies; Heparin; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Postoperative Complications; Prosthesis Failure; Recurrence; Reoperation; Retrospective Studies; Stents; Thrombolytic Therapy; Ticlopidine; Treatment Outcome | 1998 |
[Wiktor coronary stent for elective placement with an antiaggregation regimen. WINE study. WINE Group Study].
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Catheterization; Coronary Disease; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Prospective Studies; Recurrence; Risk Factors; Stents; Ticlopidine | 1998 |
[Thrombosis prophylaxis after stroke].
Topics: Anticoagulants; Aspirin; Cerebrovascular Disorders; Clopidogrel; Heparin; Humans; Middle Aged; Platelet Aggregation Inhibitors; Primary Prevention; Risk Factors; Thromboembolism; Thrombosis; Ticlopidine | 1998 |
[Thrombocyte aggregation inhibition].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Coronary Thrombosis; Humans; Intracranial Embolism and Thrombosis; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 1998 |
The antiaggregating and antithrombotic activity of clopidogrel is potentiated by aspirin in several experimental models in the rabbit.
Topics: Animals; Aspirin; Clopidogrel; Constriction, Pathologic; Drug Synergism; Femoral Artery; Fibrinolytic Agents; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thrombosis; Ticlopidine | 1998 |
Aspirin and newer orally active antiplatelet agents in the treatment of the post-myocardial infarction patient.
Topics: Administration, Oral; Aspirin; Clopidogrel; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Recurrence; Ticlopidine | 1998 |
Emergency coronary artery bypass grafting (CABG) after failed coronary artery intervention--caution regarding the combined use of aspirin, ticlopidine and abciximab.
Topics: Abciximab; Adult; Angina Pectoris; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Blood Loss, Surgical; Coronary Artery Bypass; Coronary Thrombosis; Drug Therapy, Combination; Emergencies; Humans; Immunoglobulin Fab Fragments; Infusions, Intravenous; Intraoperative Complications; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Postoperative Complications; Stents; Ticlopidine | 1998 |
New antiplatelet agents.
Topics: Abciximab; Angina, Unstable; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clopidogrel; Female; Fibrinolytic Agents; Humans; Immunoglobulin Fab Fragments; Male; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Randomized Controlled Trials as Topic; Thrombolytic Therapy; Ticlopidine | 1998 |
Coronary stenting in unstable angina: early and late clinical outcomes.
Topics: Angina, Unstable; Angioplasty, Balloon, Coronary; Aspirin; Coronary Artery Bypass; Coronary Disease; Follow-Up Studies; Humans; Myocardial Infarction; Postoperative Complications; Reoperation; Retrospective Studies; Stents; Ticlopidine; Treatment Outcome; Warfarin | 1998 |
Shifting paradigms of antiplatelet therapy: assessing new drugs versus old. Introduction.
Topics: Arteriosclerosis; Aspirin; Chemistry, Pharmaceutical; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 1998 |
Antioxidant properties of ticlopidine on human low density lipoprotein oxidation.
Topics: Amidines; Antioxidants; Ascorbic Acid; Aspirin; Free Radical Scavengers; Free Radicals; Humans; Kinetics; Lipoproteins, LDL; Oxidants; Oxidation-Reduction; Peroxides; Ticlopidine | 1998 |
Effects of clopidogrel, aspirin and combined therapy in a porcine ex vivo model of high-shear induced stent thrombosis.
Topics: Animals; Arteriovenous Shunt, Surgical; Aspirin; Bleeding Time; Blood Platelets; Clopidogrel; Coronary Vessels; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Graft Occlusion, Vascular; Platelet Aggregation; Platelet Aggregation Inhibitors; Stents; Swine; Ticlopidine | 1998 |
Antithrombotic therapy in patients with saphenous vein and internal mammary artery bypass grafts.
Topics: Anticoagulants; Aspirin; Coronary Artery Bypass; Dipyridamole; Fibrinolytic Agents; Graft Occlusion, Vascular; Humans; Internal Mammary-Coronary Artery Anastomosis; Saphenous Vein; Sulfinpyrazone; Ticlopidine | 1998 |
Primary stent implantation for acute myocardial infarction during pregnancy: use of abciximab, ticlopidine, and aspirin.
Topics: Abciximab; Adult; Antibodies, Monoclonal; Aspirin; Blood Vessel Prosthesis Implantation; Coronary Angiography; Drug Therapy, Combination; Electrocardiography; Female; Follow-Up Studies; Humans; Immunoglobulin Fab Fragments; Infant, Newborn; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Pregnancy; Pregnancy Complications, Cardiovascular; Stents; Ticlopidine | 1998 |
Procedural results and long-term clinical outcomes following coronary stenting in perimyocardial infarction syndromes.
Topics: Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Disease-Free Survival; Female; Follow-Up Studies; Heparin, Low-Molecular-Weight; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Probability; Recurrence; Stents; Thrombosis; Ticlopidine; Treatment Outcome | 1998 |
Clopidogrel inhibition of stent, graft, and vascular thrombogenesis with antithrombotic enhancement by aspirin in nonhuman primates.
Topics: Animals; Aspirin; Bleeding Time; Clopidogrel; Drug Interactions; Endarterectomy; Hemostasis; Heparin; Male; Papio; Platelet Aggregation Inhibitors; Polyethylene Terephthalates; Stents; Thrombosis; Ticlopidine | 1998 |
Coronary-artery stents--gauging, gorging, and gouging.
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Coronary Disease; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine | 1998 |
Glycoprotein IIb/IIIa inhibitors, surgery and bleeding.
Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Blood Loss, Surgical; Coronary Artery Bypass; Emergencies; Humans; Immunoglobulin Fab Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine | 1998 |
[Secondary prevention of ischemic stroke: aspirin or ticlopidine].
Topics: Aspirin; Cerebrovascular Disorders; Humans; Platelet Aggregation Inhibitors; Risk; Ticlopidine | 1998 |
Coronary artery stent placement with postprocedural antiplatelet therapy in acute myocardial infarction.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Coronary Angiography; Drug Therapy, Combination; Female; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Prospective Studies; Stents; Ticlopidine; Treatment Outcome | 1998 |
Aspirin and heparin prevent hepatic blood stasis and thrombosis induced by the toxic glycoprotein Bolesatine in mice.
Topics: Agglutination; Animals; Aspirin; Blood Platelets; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Erythrocytes; Female; Fungal Proteins; Hemostasis; Heparin; Liver Diseases; Male; Mice; Microscopy, Electron; Mycotoxins; Protein Synthesis Inhibitors; Thrombosis; Ticlopidine; Time Factors | 1998 |
Effect of glycoprotein IIb-IIIa receptor antagonism on platelet membrane glycoproteins after coronary stent placement.
Topics: Abciximab; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Binding Sites; Blood Platelets; Coronary Disease; Drug Therapy, Combination; Female; Fibrinogen; Gene Expression Regulation; Hemorrhage; Humans; Immunoglobulin Fab Fragments; Ligands; Male; Middle Aged; Myocardial Ischemia; P-Selectin; Platelet Aggregation Inhibitors; Platelet Count; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Stents; Thrombocytopenia; Ticlopidine | 1998 |
[Prevention in the 21st century. Athero-thrombosis and ischemic events].
Topics: Aspirin; Cardiovascular Diseases; Cerebrovascular Disorders; Clopidogrel; Female; Forecasting; Humans; Male; Myocardial Ischemia; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Ticlopidine | 1998 |
[Reduction of in-hospital complications after elective percutaneous transluminal coronary angioplasty using a combined pretreatment with ticlopidine and aspirin].
Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Case-Control Studies; Coronary Disease; Drug Therapy, Combination; Elective Surgical Procedures; Female; Humans; Male; Middle Aged; Postoperative Complications; Preoperative Care; Retrospective Studies; Ticlopidine | 1998 |
The lack of augmentation by aspirin of inhibition of platelet reactivity by ticlopidine.
Topics: Adenosine Diphosphate; Adult; Analysis of Variance; Anticoagulants; Aspirin; Chemoprevention; Citric Acid; Collagen; Drug Interactions; Enoxaparin; Factor XIIa; Flow Cytometry; Humans; Male; P-Selectin; Plant Proteins; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine; Trypsin Inhibitors; Zea mays | 1999 |
Timing of coronary stent thrombosis in patients treated with ticlopidine and aspirin.
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Coronary Angiography; Coronary Disease; Coronary Vessels; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Stents; Thrombosis; Ticlopidine; Time Factors; Warfarin | 1999 |
Arachidonic acid-induced hind limb gangrene: a new experimental rat model of peripheral vascular disease.
Topics: Animals; Arachidonic Acid; Aspirin; Disease Models, Animal; Disease Progression; Drug Evaluation, Preclinical; Femoral Artery; Gangrene; Hindlimb; Injections, Intra-Arterial; Male; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Ticlopidine; Vascular Diseases | 1999 |
Beneficial effect of combination antiplatelet therapy on the development of experimental Staphylococcus aureus endocarditis.
Topics: Animals; Aspirin; Drug Therapy, Combination; Endocarditis, Bacterial; Female; Platelet Aggregation Inhibitors; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Ticlopidine | 1999 |
Antithrombotic therapy after coronary-artery stenting.
Topics: Anemia, Aplastic; Aspirin; Coronary Disease; Drug Administration Schedule; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine | 1999 |
-Neonatal Kasabach-Merritt syndrome healed by complete surgical excision of the angioma-.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Back; Glucocorticoids; Hemangioma; Humans; Infant, Newborn; Male; Methylprednisolone; Platelet Aggregation Inhibitors; Skin Neoplasms; Syndrome; Thrombocytopenia; Ticlopidine | 1998 |
[The CLASSICS Study: ClopidogreL+ASA vs. Ticlopidin+ASA in patients with stents].
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 1999 |
The effects of antiplatelet agents in the prevention of ventricular tachyarrhythmias during acute myocardial ischemia in rats.
Topics: Abciximab; Animals; Antibodies, Monoclonal; Aspirin; Immunoglobulin Fab Fragments; Male; Myocardial Ischemia; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Tachycardia, Ventricular; Ticlopidine | 1999 |
[Role of antiplatelet in the prevention and treatment of thrombotic diseases].
Topics: Aspirin; Cerebrovascular Disorders; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine | 1997 |
Clopidogrel: a novel antiplatelet agent.
Topics: Adenosine Diphosphate; Aspirin; Clopidogrel; Humans; Ischemia; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine; Vascular Diseases | 1999 |
[The CLASSICS Study: Clopidogrel plus ASA vs. Ticlopidin plus ASA in stent-patients].
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 1999 |
[Effectiveness of clopidogrel and aspirin versus ticlopidine and aspirin in preventing stent thrombosis after coronary stent implantation].
Topics: Aspirin; Clopidogrel; Coronary Thrombosis; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 1999 |
Delayed traumatic hemothorax on ticlopidine and aspirin for coronary stent.
Topics: Aspirin; Coronary Disease; Hemothorax; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Rib Fractures; Stents; Ticlopidine; Time Factors | 1999 |
Secondary stroke prevention with drugs: single or combined therapy?
Topics: Anticoagulants; Aspirin; Cerebrovascular Disorders; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Ticlopidine | 1999 |
Meeting highlights. Highlights of the 48th scientific sessions of the American College of Cardiology.
Topics: Abciximab; Alanine; Angioplasty, Balloon, Coronary; Angiotensin-Converting Enzyme Inhibitors; Antibodies, Monoclonal; Aspirin; Benzamidines; Biphenyl Compounds; Cardiology; Cardiovascular Agents; Clinical Trials as Topic; Clopidogrel; Combined Modality Therapy; Coronary Disease; Dalteparin; Defibrillators, Implantable; Double-Blind Method; Enalapril; Endothelial Growth Factors; Fatty Acids, Omega-3; Guanidines; Heart Failure; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoglobulin Fab Fragments; Laser Therapy; Lymphokines; Metoprolol; Multicenter Studies as Topic; Myocardial Revascularization; Platelet Aggregation Inhibitors; Pyrrolidines; Randomized Controlled Trials as Topic; Simvastatin; Sodium-Hydrogen Exchangers; Stents; Sulfones; Thrombolytic Therapy; Ticlopidine; Tissue Plasminogen Activator; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vitamin E | 1999 |
Effectiveness of aspirin and clopidogrel combination therapy in coronary stenting.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Combined Modality Therapy; Coronary Disease; Coronary Thrombosis; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Hospital Mortality; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Recurrence; Stents; Ticlopidine; Treatment Outcome | 1999 |
Vale, warfarin: a stentorian farewell.
Topics: Animals; Anticoagulants; Aspirin; Coronary Thrombosis; Dogs; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stents; Ticlopidine; Warfarin | 1999 |
[Ticlopidine-induced cholestasis].
Topics: Aged; Aged, 80 and over; Angina Pectoris; Aspirin; Chemical and Drug Induced Liver Injury; Cholestasis; Drug Therapy, Combination; Humans; Incidence; Isosorbide Dinitrate; Liver Function Tests; Male; Metoprolol; Myocardial Infarction; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 1999 |
Taming platelets in coronary stenting: ticlopidine out, clopidogrel in?
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Combined Modality Therapy; Coronary Disease; Humans; Stents; Ticlopidine | 1999 |
Changes in prostacyclin, thromboxane A2 and F2-isoprostanes, and influence of eicosapentaenoic acid and antiplatelet agents in patients with hypertension and hyperlipidemia.
Topics: Aspirin; Dinoprost; Dipyridamole; Eicosapentaenoic Acid; Epoprostenol; Humans; Hyperlipidemias; Hypertension; Platelet Aggregation Inhibitors; Thromboxane A2; Ticlopidine | 1999 |
Hemodynamic interaction of aspirin with enalapril.
Topics: Angiotensin-Converting Enzyme Inhibitors; Aspirin; Enalapril; Heart Failure; Hemodynamics; Humans; Platelet Aggregation Inhibitors; Research Design; Ticlopidine | 1999 |
Generalizing the results of clinical trials to actual practice: the example of clopidogrel therapy for the prevention of vascular events. CAPRA (CAPRIE Actual Practice Rates Analysis) Study Group. Clopidogrel versus Aspirin in Patients at Risk of Ischaemi
Topics: Aged; Arterial Occlusive Diseases; Aspirin; Brain Ischemia; Clinical Trials as Topic; Clopidogrel; Cohort Studies; Evidence-Based Medicine; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Recurrence; Risk; Saskatchewan; Ticlopidine; Treatment Outcome | 1999 |
Thienopyridines: effects on cultured endothelial cells.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Aspirin; Calcimycin; Calcium; Cattle; Cell Line; Cell Survival; Cells, Cultured; Clopidogrel; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; Epoprostenol; Humans; Nitrites; Platelet Aggregation Inhibitors; Pyridines; Ticlopidine; Time Factors; Umbilical Veins | 1999 |
Treatment and secondary prevention of stroke.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2000 |
Studies published on clopidogrel-aspirin for coronary stent placement.
Topics: Aspirin; Clopidogrel; Coronary Thrombosis; Coronary Vessels; Drug Combinations; Humans; Platelet Aggregation Inhibitors; Postoperative Complications; Stents; Ticlopidine | 2000 |
Effects of clopidogrel on platelet activation and coagulation of non-anticoagulated rat blood under high shear stress.
Topics: Animals; Aspirin; Blood Coagulation; Clopidogrel; Hemostatic Techniques; Male; Platelet Activation; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Stress, Mechanical; Ticlopidine; Time Factors | 1999 |
Effects of ticlopidine or ticlopidine plus aspirin on platelet aggregation and ATP release in normal volunteers: why aspirin improves ticlopidine antiplatelet activity.
Topics: Adenosine Triphosphate; Aspirin; Drug Synergism; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 1999 |
Ex vivo--in vitro interaction between aspirin, clopidogrel, and the glycoprotein IIb/IIIa inhibitors abciximab and SR121566A.
Topics: Abciximab; Administration, Oral; Adult; Analysis of Variance; Antibodies, Monoclonal; Aspirin; Benzylamines; Bleeding Time; Clopidogrel; Drug Administration Schedule; Drug Interactions; Fibrinogen; Humans; Immunoglobulin Fab Fragments; Male; Nephelometry and Turbidimetry; P-Selectin; Piperidines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Reference Values; Thiazoles; Ticlopidine | 2000 |
Comparison of the effects of acetylsalicylic acid, ticlopidine and cilostazol on primary hemostasis using a quantitative bleeding time test apparatus.
Topics: Adult; Aspirin; Bleeding Time; Cilostazol; Fibrinolytic Agents; Gastrointestinal Diseases; Headache; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Tetrazoles; Ticlopidine | 1999 |
[Immortal aspirin....].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Cyclooxygenase Inhibitors; Fibrinolytic Agents; France; Germany; History, 19th Century; History, 20th Century; History, Ancient; Humans; Italy; Multicenter Studies as Topic; Platelet Aggregation Inhibitors; Ticlopidine; United Kingdom | 2000 |
[Clopidogrel--an expensive thrombocyte inhibitor with a small marginal benefit].
Topics: Aspirin; Clopidogrel; Coronary Disease; Cost-Benefit Analysis; Humans; Myocardial Ischemia; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Ticlopidine | 2000 |
[Creative mathematics with clopidogrel; exaggeration of the preventive effect by the pharmaceutical company].
Topics: Advertising; Anti-Inflammatory Agents, Non-Steroidal; Arteriosclerosis; Aspirin; Clopidogrel; Data Interpretation, Statistical; Humans; Mathematics; Netherlands; Placebo Effect; Platelet Aggregation Inhibitors; Ticlopidine | 2000 |
Long-term outcome in patients treated by intracoronary stenting with ticlopidine and aspirin, and deleterious prognostic role of unstable angina pectoris.
Topics: Aged; Angina, Unstable; Aspirin; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prognosis; Stents; Survival Analysis; Ticlopidine; Treatment Outcome | 2000 |
Saphenous vein graft disease treated with the Wiktor Hepamed stent: procedural outcome, in-hospital complications and six-month angiographic follow-up.
Topics: Aged; Aspirin; Coronary Angiography; Coronary Artery Bypass; Female; Fibrinolytic Agents; Follow-Up Studies; Graft Occlusion, Vascular; Heparin; Humans; Length of Stay; Male; Postoperative Complications; Prospective Studies; Recurrence; Saphenous Vein; Stents; Ticlopidine; Time Factors; Treatment Outcome | 2000 |
Stent-assisted angioplasty of intracranial vertebrobasilar atherosclerosis: an initial experience.
Topics: Abciximab; Adult; Aged; Angiography; Angioplasty; Antibodies, Monoclonal; Anticoagulants; Aspirin; Basilar Artery; Cerebrovascular Circulation; Clopidogrel; Female; Follow-Up Studies; Heparin; Humans; Immunoglobulin Fab Fragments; Intracranial Arteriosclerosis; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Premedication; Stents; Stroke; Subarachnoid Hemorrhage; Ticlopidine; Vertebral Artery; Vertebrobasilar Insufficiency; Warfarin | 2000 |
[Contribution of platelet aggregation inhibitors in the prevention of complications of atherothrombosis].
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Risk Factors; Thrombosis; Ticlopidine; Vascular Diseases | 2000 |
Ticlopidine plus aspirin for coronary thrombosis in Kawasaki disease.
Topics: Aspirin; Coronary Thrombosis; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Infant; Male; Mucocutaneous Lymph Node Syndrome; Platelet Aggregation Inhibitors; Ticlopidine | 2000 |
Histopathologic analysis of in-stent neointimal regression in a porcine coronary model.
Topics: Animals; Aspirin; Coronary Vessels; Disease Models, Animal; Platelet Aggregation Inhibitors; Prospective Studies; Proteoglycans; Stents; Swine; Ticlopidine; Tunica Intima; Vascular Surgical Procedures | 2000 |
Unstable angina pectoris.
Topics: Angina, Unstable; Aspirin; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2000 |
Combination therapy with clopidogrel and aspirin after coronary stenting.
Topics: Aspirin; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine; Treatment Outcome | 2000 |
[ASA or clopidogrel?].
Topics: Aspirin; Clopidogrel; Controlled Clinical Trials as Topic; Drug Costs; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine | 2000 |
Sex differences and similarities in the management and outcome of stroke patients.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Cohort Studies; Comorbidity; Diabetes Mellitus; Female; Humans; Hypertension; Male; Myocardial Ischemia; Ontario; Platelet Aggregation Inhibitors; Retrospective Studies; Sex Characteristics; Stroke; Stroke Rehabilitation; Survival Rate; Ticlopidine; Treatment Outcome; Warfarin | 2000 |
Aspirin plus extended-release dipyridamole or clopidogrel compared with aspirin monotherapy for the prevention of recurrent ischemic stroke: a cost-effectiveness analysis.
Topics: Aspirin; Clopidogrel; Cost-Benefit Analysis; Dipyridamole; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Recurrence; Stroke; Ticlopidine | 2000 |
Clopidogrel for prevention of major cardiac events after coronary stent implantation: 30-day and 6-month results in patients with smaller stents.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Disease; Cost-Benefit Analysis; Drug Costs; Equipment Design; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Prospective Studies; Registries; Stents; Ticlopidine | 2000 |
[Myocardial infarction, pregnancy and anesthesia].
Topics: Adrenergic beta-Antagonists; Adult; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Analgesics, Opioid; Angioplasty, Balloon, Coronary; Aspirin; Combined Modality Therapy; Female; Fentanyl; Fibrinolytic Agents; Heparin; Humans; Infant, Newborn; Metoprolol; Myocardial Infarction; Platelet Aggregation Inhibitors; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Outcome; Stents; Thrombolytic Therapy; Ticlopidine | 2000 |
Unusual effects of aspirin on ticlopidine induced thrombolysis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Extracorporeal Circulation; Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Thrombolytic Therapy; Thrombosis; Ticlopidine | 2000 |
Antiplatelet drugs in cardiovascular prevention: take adverse effects and costs into account.
Topics: Aspirin; Cardiovascular Diseases; Cost-Benefit Analysis; Dipyridamole; Drug Costs; Flurbiprofen; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2000 |
Antiplatelet drugs in cardiovascular prevention: coronary events: acute phase and secondary prevention.
Topics: Angina, Unstable; Angioplasty; Anticoagulants; Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Coronary Artery Bypass; Drug Therapy, Combination; Enoxaparin; Fibrinolytic Agents; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Treatment Outcome | 2000 |
Antiplatelet drugs in cardiovascular prevention: stroke: acute phase and secondary prevention.
Topics: Anticoagulants; Arrhythmia, Sinus; Aspirin; Atrial Fibrillation; Cost-Benefit Analysis; Dipyridamole; Drug Therapy, Combination; Heparin; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2000 |
Antiplatelet drugs in cardiovascular prevention: coronary events and stroke: primary prevention.
Topics: Aspirin; Carotid Stenosis; Cost-Benefit Analysis; Diabetes Mellitus; Digestive System; Female; Humans; Hypertension; Leg; Male; Middle Aged; Myocardial Infarction; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Risk Factors; Stroke; Ticlopidine | 2000 |
Cost-effectiveness of new antiplatelet regimens used as secondary prevention of stroke or transient ischemic attack.
Topics: Aged; Aspirin; Clopidogrel; Cost-Benefit Analysis; Decision Trees; Dipyridamole; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Markov Chains; Platelet Aggregation Inhibitors; Quality-Adjusted Life Years; Recurrence; Stroke; Ticlopidine | 2000 |
[New antiplatelet agents].
Topics: Abciximab; Acetates; Antibodies, Monoclonal; Anticoagulants; Aspirin; Clopidogrel; Cyclooxygenase Inhibitors; Dipyridamole; Fibrinolytic Agents; Humans; Immunoglobulin Fab Fragments; Phosphodiesterase Inhibitors; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Risk Factors; Ticlopidine; Tirofiban; Tyrosine | 2000 |
Ticlopidine, Alka-Seltzer, or a combination of citric acid with aspirin: effects on platelet aggregation in individuals with an insufficient response to aspirin alone.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Citrates; Citric Acid; Drug Combinations; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Sodium Bicarbonate; Ticlopidine | 2000 |
[Calculation of costs of stroke, cost effectiveness of stroke units and secondary prevention in patients after a stroke, as recommended by revised CBO practice guideline 'Stroke'].
Topics: Age Factors; Aspirin; Clopidogrel; Cost-Benefit Analysis; Dipyridamole; Drug Costs; Health Care Costs; Humans; Intensive Care Units; Length of Stay; Models, Economic; Netherlands; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Secondary Prevention; Sex Factors; Stroke; Ticlopidine | 2000 |
[Old and new platelet aggregation inhibitors: which to choose for prevention of stroke?].
Topics: Aspirin; Clopidogrel; Dipyridamole; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Stroke; Ticlopidine | 2000 |
[Prevention of thromboembolic disease in patients with heart disease].
Topics: Age Factors; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Cross-Sectional Studies; Dipyridamole; Female; Heart Diseases; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Salicylates; Sex Factors; Thromboembolism; Ticlopidine | 2000 |
Successful management of intractable coronary spasm with a coronary stent.
Topics: Adult; Amlodipine; Aspirin; Calcium Channel Blockers; Cardiovascular Agents; Coronary Angiography; Coronary Artery Disease; Coronary Vasospasm; Diltiazem; Doxazosin; Drug Resistance; Drug Therapy, Combination; Ergonovine; Humans; Isosorbide Dinitrate; Male; Myocardial Infarction; Nicorandil; Nitrates; Pyridines; Stents; Ticlopidine; Ventricular Fibrillation | 2000 |
Ticlopidine and aspirin fail to suppress the increased platelet aggregability that follows percutaneous coronary interventions.
Topics: Aged; Angina Pectoris; Angioplasty, Balloon; Aspirin; Blood Coagulation Tests; Coronary Angiography; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation; Ticlopidine | 2000 |
Active-control trials: how would a new agent compare with placebo? A method illustrated with clopidogrel, aspirin, and placebo.
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Humans; Odds Ratio; Placebos; Platelet Aggregation Inhibitors; Ticlopidine | 2001 |
Diabetes mellitus with left transverse sinus thrombosis and right transverse sinus aplasia.
Topics: Aged; Aspirin; Cerebral Angiography; Cranial Sinuses; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diet, Diabetic; Female; Fibrinolytic Agents; Headache; Humans; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Metformin; Sinus Thrombosis, Intracranial; Ticlopidine; Tomography, X-Ray Computed; Urokinase-Type Plasminogen Activator | 2001 |
Combination therapy with aspirin plus clopidogrel versus aspirin plus ticlopidine for prevention of subacute thrombosis after successful native coronary stenting.
Topics: Aged; Aspirin; Clopidogrel; Coronary Angiography; Coronary Disease; Drug Therapy, Combination; Female; Humans; Male; Platelet Aggregation Inhibitors; Retrospective Studies; Stents; Thrombosis; Ticlopidine; Treatment Outcome; Ultrasonography, Interventional | 2001 |
[2 platelet inhibitors administered at the same time. Improved prognosis in myocardial infarct?]].
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Prognosis; Ticlopidine | 2001 |
[Late stent thrombosis after intracoronary brachytherapy. A case report and review of the literature].
Topics: Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; Brachytherapy; Clinical Trials as Topic; Coronary Angiography; Coronary Disease; Electrocardiography; Fibrinolytic Agents; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Recurrence; Stents; Strontium Radioisotopes; Thrombosis; Ticlopidine; Time Factors; Ultrasonography, Interventional; Yttrium Radioisotopes | 2001 |
Newer antiplatelet therapies in stroke prevention.
Topics: Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2001 |
Platelet and leukocyte deactivation after intracoronary stent placement in patients receiving combined antiplatelet therapy.
Topics: Adult; Angioplasty, Balloon, Coronary; Aspirin; Biomarkers; Drug Therapy, Combination; E-Selectin; Female; Humans; L-Selectin; Leukocytes; Lymphocyte Activation; Male; Middle Aged; Neutrophil Activation; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2001 |
Short-term outcome of stent implantation in saphenous vein grafts: predictors of distal embolization and restenosis.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Combined Modality Therapy; Comorbidity; Coronary Angiography; Coronary Artery Bypass; Coronary Disease; Drug Therapy, Combination; Embolism; Female; Fibrinolytic Agents; Follow-Up Studies; Graft Occlusion, Vascular; Heparin; Humans; Japan; Male; Middle Aged; Recurrence; Retrospective Studies; Risk Factors; Saphenous Vein; Stents; Ticlopidine; Treatment Outcome; Warfarin | 2001 |
Edge stenosis after intracoronary radiotherapy: angiographic, intravascular, and histological findings.
Topics: Aged; Angioplasty, Balloon, Laser-Assisted; Anticoagulants; Aspirin; Brachytherapy; Clopidogrel; Combined Modality Therapy; Coronary Angiography; Coronary Stenosis; Humans; Hyperlipidemias; Hypertension; Iridium Radioisotopes; Male; Myocardial Revascularization; Recurrence; Reoperation; Stents; Ticlopidine | 2001 |
[Pharmacy clinics. Medication of the month. Clopidogrel (Plavix)].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arteriosclerosis; Aspirin; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Humans; Myocardial Ischemia; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stroke; Ticlopidine | 2001 |
[Acute heart attacks. Prognosis can be further improved].
Topics: Adrenergic beta-Antagonists; Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Prognosis; Survival Rate; Ticlopidine | 2001 |
[Pathophysiology of platelet activation and pharmacology of GPIIb/IIIa inhibitors].
Topics: Abciximab; Antibodies, Monoclonal; Aspirin; Blood Platelets; Clopidogrel; Eptifibatide; Fibrinolytic Agents; Humans; Immunoglobulin Fab Fragments; Peptides; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Risk Factors; Ticlopidine; Tirofiban; Tyrosine | 2001 |
[Optimal platelet inhibition therapy in unstable angina pectoris and after coronary interventions].
Topics: Angina, Unstable; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Fibrinolytic Agents; Heparin; Humans; Multicenter Studies as Topic; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine; Time Factors | 2001 |
CURE--clopidogrel's major advance.
Topics: Aspirin; Brain Ischemia; Clinical Trials as Topic; Clopidogrel; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2001 |
Platelets modulate gastric ulcer healing: role of endostatin and vascular endothelial growth factor release.
Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Blood Platelets; Cell Division; Cells, Cultured; Collagen; Disease Models, Animal; Endostatins; Endothelial Growth Factors; Endothelium, Vascular; Humans; Lymphokines; Male; Neovascularization, Pathologic; Peptide Fragments; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Stomach Ulcer; Ticlopidine; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Wound Healing | 2001 |
Effect of cilostazol on restenosis after coronary angioplasty and stenting in comparison to conventional coronary artery stenting with ticlopidine.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Coronary Disease; Drug Therapy, Combination; Female; Humans; Japan; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Recurrence; Retrospective Studies; Stents; Tetrazoles; Ticlopidine | 2001 |
The inhibition of oxygen radical release from human neutrophils by resting platelets is reversed by administration of acetylsalicylic acid or clopidogrel.
Topics: Adult; Aspirin; Blood Platelets; Cell Respiration; Cells, Cultured; Clopidogrel; Female; Free Radicals; Humans; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Platelet Aggregation Inhibitors; Ticlopidine | 2001 |
Ticlopidine monotherapy following coronary stent deployment: "penny wise and pound foolish".
Topics: Aspirin; Coronary Disease; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2001 |
Clinical correlates and drug treatment of residents with stroke in long-term care.
Topics: Aged; Aged, 80 and over; Aspirin; Cognition Disorders; Comorbidity; Cross-Sectional Studies; Databases, Factual; Dipyridamole; Drug Therapy, Combination; Female; Humans; Inpatients; Logistic Models; Long-Term Care; Male; Nursing Homes; Odds Ratio; Prevalence; Risk Assessment; Risk Factors; Severity of Illness Index; Stroke; Ticlopidine; United States; Warfarin | 2001 |
[Superiority of clopidogrel versus aspirin in patients with prior cardiac surgery].
Topics: Aspirin; Clopidogrel; Coronary Disease; Humans; Platelet Aggregation Inhibitors; Postoperative Complications; Ticlopidine | 2001 |
Clinical application of procedural platelet monitoring during percutaneous coronary intervention among patients at increased bleeding risk.
Topics: Abciximab; Adult; Aged; Aged, 80 and over; Angina, Unstable; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Aspirin; Carotid Stenosis; Clopidogrel; Comorbidity; Coronary Artery Bypass; Drug Therapy, Combination; Female; Fibrinogen; Graft Occlusion, Vascular; Hemorrhage; Humans; Immunoglobulin Fab Fragments; Male; Microspheres; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Recurrence; Risk; Stents; Ticlopidine | 2001 |
Is ticlopidine more effective than aspirin in preventing adverse cardiovascular events after myocardial infarction (MI)?
Topics: Angina Pectoris; Aspirin; Double-Blind Method; Fibrinolytic Agents; Humans; Multicenter Studies as Topic; Myocardial Infarction; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stroke; Ticlopidine | 2001 |
Clopidogrel: new preparation. An alternative to aspirin.
Topics: Aspirin; Clinical Trials as Topic; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Treatment Outcome | 1999 |
Ticlopidine: a second look. No further use in routine practice.
Topics: Aspirin; Clinical Trials as Topic; Fibrinolytic Agents; Humans; Stroke; Ticlopidine; Treatment Outcome | 1999 |
Late acute thrombosis after paclitaxel eluting stent implantation.
Topics: Acute Disease; Angiogenesis Inhibitors; Aspirin; Coronary Disease; Coronary Thrombosis; Drug Implants; Humans; Male; Middle Aged; Myocardial Infarction; Paclitaxel; Platelet Aggregation Inhibitors; Recurrence; Risk Factors; Stents; Ticlopidine; Time Factors | 2001 |
Clopidogrel in invasive management of non-ST-elevation ACS.
Topics: Angina, Unstable; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Disease; Humans; Myocardial Ischemia; Myocardial Revascularization; Platelet Aggregation Inhibitors; Preoperative Care; Ticlopidine; Treatment Outcome | 2001 |
[Cost effectiveness of clopidogrel in secondary cardiovascular prevention: a cost-effectiveness analysis based on the Caprie Study].
Topics: Adult; Aged; Arterial Occlusive Diseases; Aspirin; Cerebral Hemorrhage; Cerebral Infarction; Clopidogrel; Cost-Benefit Analysis; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Assessment; Switzerland; Ticlopidine | 2001 |
[Antithrombotic therapy of unstable angina pectoris].
Topics: Angina, Unstable; Aspirin; Drug Therapy, Combination; Fibrinolytic Agents; Heparin; Humans; Myocardial Infarction; Ticlopidine; Tirofiban; Tyrosine | 1998 |
Prevention of venous graft sclerosis with clopidogrel and aspirin combined with a mesh tubing in a dog model of arteriovenous bypass grafting.
Topics: Animals; Aspirin; Blood Vessel Prosthesis; Carotid Artery, Common; Clopidogrel; Dogs; Drug Therapy, Combination; Graft Occlusion, Vascular; Jugular Veins; Platelet Aggregation Inhibitors; Ticlopidine | 2001 |
Effect of clopidogrel added to aspirin before percutaneous coronary intervention on the risk associated with C-reactive protein.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; C-Reactive Protein; Clopidogrel; Female; Humans; Male; Myocardial Infarction; Ohio; Platelet Aggregation Inhibitors; Premedication; Registries; Stents; Survival Analysis; Ticlopidine; Treatment Outcome | 2001 |
Acute myocardial infarction 2000 treatment.
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Heparin; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Practice Guidelines as Topic; Primary Health Care; Thrombolytic Therapy; Ticlopidine; United States | 2001 |
Clopidogrel versus aspirin after cardiac surgery.
Topics: Aspirin; Clopidogrel; Humans; Myocardial Ischemia; Platelet Aggregation Inhibitors; Postoperative Care; Randomized Controlled Trials as Topic; Risk Factors; Ticlopidine; Treatment Outcome | 2001 |
Coronary stent thrombosis: insights from the porcine coronary stent model.
Topics: Animals; Anticoagulants; Aspirin; Clopidogrel; Coronary Stenosis; Coronary Thrombosis; Coronary Vessels; Drug Therapy, Combination; Heparin; Humans; Models, Animal; Myocardial Infarction; Stents; Swine; Ticlopidine | 2001 |
[Clopidogrel in acute coronary syndromes with non-ST elevation. Clinical implications of the CURE trial].
Topics: Angina, Unstable; Aspirin; Clopidogrel; Cost-Benefit Analysis; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Myocardial Infarction; Patient Selection; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Randomized Controlled Trials as Topic; Syndrome; Ticlopidine; Treatment Outcome | 2001 |
Coronary stent deployment in situs inversus.
Topics: Aged; Aspirin; Chest Pain; Clopidogrel; Coronary Artery Disease; Dextrocardia; Electrocardiography; Humans; Male; Situs Inversus; Stents; Ticlopidine | 2001 |
Effects of the antiplatelet agent TA-993 and its metabolite MB3 on the hemorheological properties of rat and human erythrocytes.
Topics: Animals; Aspirin; Blood Viscosity; Diltiazem; Dose-Response Relationship, Drug; Erythrocytes; Hemolysis; Hemorheology; Humans; Phospholipids; Platelet Aggregation Inhibitors; Rats; Ticlopidine | 2001 |
Effects of ticlopidine on von Willebrand factor-mediated shear-induced platelet activation and aggregation.
Topics: Adult; Aspirin; Blood Platelets; Hemorheology; Humans; Kinetics; Male; Membrane Proteins; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Binding; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Stress, Mechanical; Ticlopidine; von Willebrand Factor | 2001 |
Antithrombotic drugs for secondary stroke prophylaxis--a comment.
Topics: Aspirin; Aspirin, Dipyridamole Drug Combination; Clopidogrel; Dipyridamole; Drug Combinations; Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2001 |
Antiplatelet therapy: a vascular medicine perspective.
Topics: Aspirin; Humans; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Ticlopidine; United States | 2000 |
Antiplatelet therapy: a neurology perspective.
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Humans; Neurology; Platelet Aggregation Inhibitors; Risk Factors; Stroke; Ticlopidine; United States | 2000 |
Antiplatelet therapy: a neurology perspective.
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Humans; Neurology; Platelet Aggregation Inhibitors; Risk Factors; Stroke; Ticlopidine; United States | 2000 |
Antiplatelet therapy: a vascular medicine perspective.
Topics: Aspirin; Clopidogrel; Humans; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Ticlopidine; United States | 2000 |
Dual antiplatelet therapy with clopidogrel and aspirin after carotid artery stenting.
Topics: Aged; Aged, 80 and over; Aspirin; Carotid Stenosis; Clopidogrel; Combined Modality Therapy; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prosthesis Implantation; Stents; Stroke; Survival Analysis; Ticlopidine | 2001 |
Aspirin plus clopidogrel for everyone: panacea comes true in the 21st century.
Topics: Aspirin; Clopidogrel; Coronary Thrombosis; Humans; Platelet Aggregation Inhibitors; Postoperative Complications; Prosthesis Implantation; Stents; Ticlopidine | 2001 |
Haemorrhage associated with combined clopidogrel and aspirin therapy.
Topics: Aged; Aged, 80 and over; Aortic Aneurysm, Abdominal; Aspirin; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine | 2001 |
Current strategies of secondary prevention after a cerebrovascular event: the Vienna stroke registry.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Austria; Clopidogrel; Cohort Studies; Comorbidity; Contraindications; Cross-Sectional Studies; Dipyridamole; Drug Combinations; Female; Humans; Intracranial Embolism; Ischemic Attack, Transient; Logistic Models; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Registries; Secondary Prevention; Stroke; Ticlopidine | 2001 |
Intracoronary stent implantation under intracoronary ultrasound guidance with aspirin and ticlopidine therapy.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Combined Modality Therapy; Coronary Disease; Female; Fibrinolytic Agents; Follow-Up Studies; Humans; Male; Middle Aged; Stents; Ticlopidine; Treatment Outcome; Ultrasonography, Interventional | 2001 |
Treatment of acute coronary syndromes.
Topics: Acute Disease; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Meta-Analysis as Topic; Myocardial Ischemia; Platelet Aggregation Inhibitors; Risk; Ticlopidine | 2002 |
Treatment of acute coronary syndromes.
Topics: Acute Disease; Aspirin; Clopidogrel; Combined Modality Therapy; Drug Therapy, Combination; Humans; Myocardial Ischemia; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Risk Factors; Stents; Ticlopidine | 2002 |
Treatment of acute coronary syndromes.
Topics: Acute Disease; Aspirin; Clopidogrel; Creatine Kinase; Creatine Kinase, MB Form; Drug Therapy, Combination; Humans; Isoenzymes; Myocardial Ischemia; Myocardial Revascularization; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine; Troponin | 2002 |
Treatment of acute coronary syndromes.
Topics: Acute Disease; Aspirin; Clopidogrel; Coronary Artery Bypass; Drug Therapy, Combination; Hemorrhage; Humans; Myocardial Ischemia; Platelet Aggregation Inhibitors; Postoperative Complications; Ticlopidine | 2002 |
Aspirin versus clopidogrel for synthetic graft patency after peripheral arterial bypass grafting.
Topics: Arteries; Aspirin; Blood Vessel Prosthesis; Clopidogrel; Graft Occlusion, Vascular; Humans; Male; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Ticlopidine; Vascular Patency | 2001 |
Effect of clopidogrel on bleeding after coronary artery bypass surgery.
Topics: Aspirin; Blood Transfusion; Case-Control Studies; Clopidogrel; Coronary Artery Bypass; Drug Therapy, Combination; Female; Humans; Incidence; Logistic Models; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Prospective Studies; Reoperation; Risk Factors; Statistics, Nonparametric; Tennessee; Ticlopidine | 2001 |
OPCAB therapy survey: off-pump clopidogrel, aspirin or both therapy survey.
Topics: Anticoagulants; Aspirin; Canada; Cardiology; Clopidogrel; Combined Modality Therapy; Coronary Artery Bypass; Data Collection; Drug Therapy, Combination; Humans; Intraoperative Complications; Platelet Aggregation Inhibitors; Postoperative Complications; Ticlopidine; Treatment Outcome; United States | 2001 |
Thrombostatin inhibits cyclic flow variations in stenosed canine coronary arteries.
Topics: Animals; Aspirin; Blood Coagulation Tests; Bradykinin; Clopidogrel; Coronary Stenosis; Coronary Thrombosis; Disease Models, Animal; Dogs; Drug Evaluation; Metabolic Clearance Rate; Peptide Fragments; Platelet Function Tests; Regional Blood Flow; Therapeutic Equivalency; Ticlopidine; Time Factors | 2001 |
Clopidogrel--a myocardial infarction CURE?
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine | 2001 |
Oral anticoagulation for acute coronary syndromes.
Topics: Administration, Oral; Aged; Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Aspirin; Clopidogrel; Controlled Clinical Trials as Topic; Diabetes Complications; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Echocardiography; Electrocardiography; Female; Humans; International Normalized Ratio; Male; Middle Aged; Myocardial Infarction; Patient Care Planning; Risk Factors; Stroke; Thrombosis; Ticlopidine; Warfarin | 2002 |
Thrombus formation on guide wires during routine PTCA procedures: a scanning electron microscopic evaluation.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Coated Materials, Biocompatible; Coronary Thrombosis; Equipment Design; Equipment Safety; Female; Fibrinolytic Agents; Humans; Male; Microscopy, Electron, Scanning; Middle Aged; Phosphorylcholine; Polytetrafluoroethylene; Prevalence; Quebec; Severity of Illness Index; Silicones; Ticlopidine; Time Factors; Treatment Outcome | 2002 |
Same-day transradial outpatient stenting with a 6-hr course of glycoprotein IIb/IIIa receptor blockade: a feasibility study.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Angioplasty, Balloon, Coronary; Aspirin; Blood Vessel Prosthesis Implantation; Clopidogrel; Coronary Artery Disease; Coronary Vessels; Creatine Kinase; Electrocardiography; Feasibility Studies; Female; Follow-Up Studies; Humans; Length of Stay; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Stents; Stroke Volume; Ticlopidine; Time Factors; Treatment Outcome | 2002 |
[Two platelet inhibitors after acute coronary syndrome. Many colleagues are not aware of this].
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Survival Rate; Ticlopidine | 2002 |
[Report of a patient with spontaneous aggregation of his giant and morphologically abnormal platelets].
Topics: Aspirin; Bernard-Soulier Syndrome; Blood Platelet Disorders; Cell Size; Child; Cytoplasmic Granules; Female; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Ticlopidine | 2002 |
Combined therapy with clopidogrel and aspirin significantly increases the bleeding time through a synergistic antiplatelet action.
Topics: Adult; Aspirin; Bleeding Time; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors | 2002 |
Cost effectiveness of aspirin, clopidogrel, or both for secondary prevention of coronary heart disease.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Computer Simulation; Coronary Disease; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combination; Humans; Middle Aged; Models, Econometric; Platelet Aggregation Inhibitors; Quality-Adjusted Life Years; Ticlopidine | 2002 |
When increased therapeutic benefit comes at increased cost.
Topics: Aspirin; Clopidogrel; Coronary Disease; Cost-Benefit Analysis; Drug Costs; Platelet Aggregation Inhibitors; Quality-Adjusted Life Years; Ticlopidine | 2002 |
[Risk improves effectiveness. Proper administration of platelet aggregation inhibitors].
Topics: Aspirin; Cerebral Infarction; Clopidogrel; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk; Ticlopidine; Treatment Outcome | 2002 |
[New US guidelines. Myocardial infarct is now treated more aggressively].
Topics: Angina, Unstable; Aspirin; Cerebral Infarction; Clopidogrel; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Ticlopidine; United States | 2002 |
Clopidogrel as an antiplatelet agent in transplant heart coronary stenting.
Topics: Aspirin; Clopidogrel; Coronary Thrombosis; Drug Therapy, Combination; Heart Transplantation; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Treatment Outcome | 2002 |
Aspirin should be first-line antiplatelet therapy in the secondary prevention of stroke.
Topics: Aspirin; Clopidogrel; Dipyridamole; Dose-Response Relationship, Drug; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stroke; Ticlopidine; Treatment Outcome | 2002 |
Aspirin therapy should be first-line treatment in secondary prevention of stroke--against.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Dipyridamole; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Multicenter Studies as Topic; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk; Stroke; Ticlopidine; Treatment Outcome | 2002 |
Aspirin therapy should be first line: probably, but watch this space.
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Drug Synergism; Humans; Myocardial Ischemia; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Treatment Outcome | 2002 |
Abciximab therapy improves 1-month survival rate in unselected patients with acute myocardial infarction undergoing routine infarct artery stent implantation.
Topics: Abciximab; Aged; Antibodies, Monoclonal; Aspirin; Cohort Studies; Contraindications; Coronary Angiography; Drug Therapy, Combination; Female; Humans; Immunoglobulin Fab Fragments; Male; Myocardial Infarction; Regression Analysis; Stents; Survival Rate; Ticlopidine | 2002 |
Acute peripheral arterial ischemia and suspected aortic dissection: usefulness of transesophageal echocardiography in differential diagnosis with aortic thrombosis.
Topics: Acute Disease; Adult; Aged; Amputation, Surgical; Anticoagulants; Aortic Diseases; Arterial Occlusive Diseases; Aspirin; Clopidogrel; Diagnosis, Differential; Echocardiography, Transesophageal; Female; Follow-Up Studies; Humans; Ischemia; Leg; Male; Middle Aged; Spain; Thrombectomy; Thrombosis; Ticlopidine; Tomography, X-Ray Computed; Treatment Outcome; Warfarin | 2002 |
[Long-term anticoagulation after bypass operation].
Topics: Arterial Occlusive Diseases; Aspirin; Clopidogrel; Humans; Long-Term Care; Platelet Aggregation Inhibitors; Postoperative Complications; Recurrence; Ticlopidine | 2002 |
CURE works patients with acute coronary syndromes at all risk levels.
Topics: Acute Disease; Aspirin; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk; Risk Assessment; Secondary Prevention; Ticlopidine | 2002 |
Inhibition of ADP-induced P-selectin expression and platelet-leukocyte conjugate formation by clopidogrel and the P2Y12 receptor antagonist AR-C69931MX but not aspirin.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Aspirin; Blood Platelets; Cell Adhesion; Clopidogrel; Drug Therapy, Combination; Female; Humans; Leukocytes; Male; Membrane Proteins; Middle Aged; Myocardial Ischemia; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Stents; Ticlopidine | 2002 |
Acute pulmonary embolism: don't ignore the platelet.
Topics: Acute Disease; Animals; Anticoagulants; Aspirin; Blood Platelets; Clinical Trials as Topic; Clopidogrel; Disease Models, Animal; Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pulmonary Embolism; Secondary Prevention; Ticlopidine | 2002 |
Therapy of Sneddon syndrome.
Topics: Adult; Antibodies, Antiphospholipid; Anticonvulsants; Aspirin; Azathioprine; Clopidogrel; Drug Therapy, Combination; Epilepsy; Female; Humans; Immunosuppressive Agents; Platelet Aggregation Inhibitors; Sneddon Syndrome; Ticlopidine; Valproic Acid | 2002 |
Large intracoronary thrombi with good TIMI flow during acute myocardial infarction: four cases of successful aggressive medical management in patients without angiographically detectable coronary atherosclerosis.
Topics: Abciximab; Adult; Antibodies, Monoclonal; Anticoagulants; Aspirin; Clopidogrel; Coronary Circulation; Coronary Thrombosis; Drug Therapy, Combination; Female; Heparin; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine | 2002 |
Influence of nitric oxide on the in vitro antiaggregant effect of ticlopidine.
Topics: Adult; Analysis of Variance; Aspirin; Humans; In Vitro Techniques; Male; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2002 |
Clopidogrel plus aspirin for stroke prevention.
Topics: Angina, Unstable; Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Follow-Up Studies; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Risk; Secondary Prevention; Stroke; Ticlopidine; Treatment Outcome | 2002 |
Effects of combined therapy of clopidogrel and aspirin in preventing thrombus formation on mechanical heart valves in an ex vivo rabbit model.
Topics: Animals; Aspirin; Clopidogrel; Drug Evaluation, Preclinical; Drug Therapy, Combination; Heart Valve Prosthesis; In Vitro Techniques; Male; Microscopy, Electron; Rabbits; Thrombosis; Ticlopidine; Warfarin | 2002 |
A partial CURE for acute coronary syndromes--but how did it happen?
Topics: Angina, Unstable; Aspirin; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2002 |
Frequency and correlates of coronary stent thrombosis in the modern era: analysis of a single center registry.
Topics: Aged; Aged, 80 and over; Angina, Unstable; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Thrombosis; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Registries; Retrospective Studies; Risk Factors; Stents; Ticlopidine; Treatment Outcome | 2002 |
New treatment guidelines for unstable angina/non-ST-segment elevation myocardial infartion.
Topics: Angina, Unstable; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Heparin, Low-Molecular-Weight; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Ticlopidine | 2002 |
[New guidelines in acute coronary syndrome. Clopidogrel for nine months is recommended].
Topics: Angina, Unstable; Aspirin; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Survival Rate; Ticlopidine | 2002 |
Serious adverse vascular events associated with perioperative interruption of antiplatelet and anticoagulant therapy.
Topics: Aged; Anticoagulants; Aspirin; Carcinoma, Basal Cell; Clopidogrel; Drug Administration Schedule; Female; Heparin, Low-Molecular-Weight; Humans; Mohs Surgery; Nose Neoplasms; Platelet Aggregation Inhibitors; Postoperative Complications; Practice Guidelines as Topic; Skin Neoplasms; Ticlopidine; Venous Thrombosis | 2002 |
Stroke prevention in patients with atrial fibrillation.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Drug Prescriptions; Female; Fibrinolytic Agents; Humans; Male; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Warfarin | 2003 |
Influence of heparin coating of coronary stents and ex vivo efficacy of different doses of acetylsalicylic acid and ticlopidine in a pulsed floating model of recirculating human plasma.
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Coated Materials, Biocompatible; Coronary Vessels; Heparin; Humans; Male; Models, Cardiovascular; Platelet Aggregation; Platelet Aggregation Inhibitors; Reference Values; Stents; Ticlopidine | 2002 |
Ischaemic stroke in young people: a prospective and long-term follow-up study.
Topics: Acenocoumarol; Adolescent; Adult; Anticoagulants; Aspirin; Brain Ischemia; Disability Evaluation; Echocardiography, Transesophageal; Female; Fibrinolytic Agents; Follow-Up Studies; Humans; Italy; Magnetic Resonance Angiography; Male; Middle Aged; Patient Compliance; Patient Satisfaction; Prevalence; Prognosis; Prospective Studies; Recurrence; Risk Factors; Severity of Illness Index; Stroke; Ticlopidine; Time Factors; Tomography, X-Ray Computed; Ultrasonography, Doppler, Color | 2003 |
Thrombophilic causes of retinal vascular thrombosis: etiology and treatment outcomes.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Clinical Laboratory Techniques; Clopidogrel; Dalteparin; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Retinal Diseases; Retinal Vessels; Thrombophilia; Thrombosis; Ticlopidine; Treatment Outcome | 2002 |
Influence of residual stenosis after percutaneous coronary intervention with stent implantation on development of restenosis and stent thrombosis.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Coronary Angiography; Coronary Restenosis; Coronary Thrombosis; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Regression Analysis; Stents; Ticlopidine | 2003 |
[In acute coronary syndrome. Seize platelets with pliers].
Topics: Acute Disease; Angina, Unstable; Aspirin; Clinical Trials as Topic; Clopidogrel; Cyclooxygenase Inhibitors; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk Factors; Syndrome; Ticlopidine; Time Factors | 2002 |
Optimal treatment and current situation in reperfusion after thrombolysis for acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Angioplasty; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Aspirin; Calcium Channel Blockers; Clopidogrel; Electrocardiography; Fibrinolytic Agents; Heparin; Humans; Myocardial Infarction; Myocardial Reperfusion; Nitroprusside; Pacemaker, Artificial; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombin; Thrombolytic Therapy; Ticlopidine | 2002 |
Aspirin, clopidogrel, or both for secondary prevention of coronary disease.
Topics: Aspirin; Clopidogrel; Coronary Disease; Cost-Benefit Analysis; Drug Costs; Drug Industry; Fees, Pharmaceutical; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2003 |
Aspirin, clopidogrel, or both for secondary prevention of coronary disease.
Topics: Aspirin; Clopidogrel; Coronary Disease; Cost-Benefit Analysis; Data Interpretation, Statistical; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Risk; Ticlopidine | 2003 |
Aspirin, clopidogrel, or both for secondary prevention of coronary disease.
Topics: Aspirin; Clopidogrel; Coronary Disease; Cost-Benefit Analysis; Data Interpretation, Statistical; Drug Costs; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk; Ticlopidine | 2003 |
Aspirin, clopidogrel, or both for secondary prevention of coronary disease.
Topics: Aspirin; Clopidogrel; Coronary Disease; Cost-Benefit Analysis; Drug Costs; Drug Industry; Fees, Pharmaceutical; Health Expenditures; Humans; Platelet Aggregation Inhibitors; Quality-Adjusted Life Years; Ticlopidine | 2003 |
Aspirin, clopidogrel, or both for secondary prevention of coronary disease.
Topics: Aspirin; Clopidogrel; Coronary Disease; Cost-Benefit Analysis; Humans; Medically Uninsured; Platelet Aggregation Inhibitors; Ticlopidine; United States | 2003 |
Antiplatelet effects of angiotensin-converting enzyme inhibitors compared with aspirin and clopidogrel: a pilot study with whole-blood aggregometry.
Topics: Adenosine Diphosphate; Adult; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Case-Control Studies; Clopidogrel; Coronary Disease; Female; Humans; Hypertension; Male; Middle Aged; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine | 2003 |
Pharmacological treatment of acute coronary syndromes.
Topics: Adrenergic beta-Antagonists; Angina, Unstable; Aspirin; Clopidogrel; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Syndrome; Ticlopidine | 2003 |
Embolic attack in patients with atrial fibrillation and atrial thrombus depends on the character of the thrombus.
Topics: Aged; Aspirin; Atrial Fibrillation; Disease-Free Survival; Drug Therapy, Combination; Echocardiography, Transesophageal; Embolism; Female; Heart Atria; Humans; Male; Middle Aged; Practice Guidelines as Topic; Predictive Value of Tests; Survival Analysis; Thrombosis; Ticlopidine; Warfarin | 2003 |
[After the heart catheter. 2 thrombocyte inhibitors for a whole year?].
Topics: Aspirin; Cardiac Catheterization; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Humans; Long-Term Care; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2003 |
Clopidogrel but not aspirin reduces P-selectin expression and formation of platelet-leukocyte aggregates in patients with atherosclerotic vascular disease.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Case-Control Studies; Clopidogrel; Coronary Artery Disease; Cross-Sectional Studies; Drug Therapy, Combination; Dual Specificity Phosphatase 2; Female; Flow Cytometry; Humans; Intercellular Adhesion Molecule-1; Leukocytes; Male; Middle Aged; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Phosphatase 2; Protein Tyrosine Phosphatases; Ticlopidine | 2003 |
Spontaneous hemarthrosis of the knee associated with clopidogrel and aspirin treatment.
Topics: Aged; Angina, Unstable; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Coagulation Tests; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Hemarthrosis; Humans; Male; Myocardial Infarction; Osteoarthritis, Knee; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Risk Factors; Ticlopidine | 2003 |
Is aspirin still the antiplatelet drug of choice for patients with peripheral arterial disease?
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Humans; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Ticlopidine | 2003 |
I'm a 65-year-old man with high blood pressure and a family history of stroke. Which stroke-prevention medication would be better for me--aspirin or clopidogrel (Plavix)?
Topics: Aged; Aspirin; Clopidogrel; Family Health; Humans; Hypertension; Life Style; Male; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2003 |
[New antiaggregants and their importance for the practitioner].
Topics: Abciximab; Administration, Oral; Adult; Anesthesia, Spinal; Antibodies, Monoclonal; Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Contraindications; Drug Therapy, Combination; Eptifibatide; Female; Fibrinolytic Agents; Hemorrhage; Humans; Immunoglobulin Fab Fragments; Male; Peptides; Placebos; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pregnancy; Ticlopidine; Tirofiban; Tyrosine | 2003 |
[Anticoagulation and antiaggregation in cardiac patients].
Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Fibrinolytic Agents; Heart Valve Prosthesis; Hemorrhage; Humans; Myocardial Infarction; Placebos; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Primary Prevention; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Thromboembolism; Ticlopidine | 2003 |
[Anticoagulation and antiaggregation in neurological patients].
Topics: Acute Disease; Administration, Oral; Aged; Anticoagulants; Aspirin; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Fibrinolytic Agents; Heparin; Humans; Meta-Analysis as Topic; Middle Aged; Placebos; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Recurrence; Risk Factors; Stroke; Ticlopidine; Warfarin | 2003 |
[Anticoagulation and antiaggregation in patients with peripheral arterial occlusive diseases].
Topics: Administration, Oral; Angioplasty, Balloon; Anticoagulants; Arterial Occlusive Diseases; Aspirin; Blood Vessel Prosthesis; Clopidogrel; Confidence Intervals; Dipyridamole; Drug Therapy, Combination; Embolectomy; Fibrinolytic Agents; Heparin; Heparin, Low-Molecular-Weight; Humans; Iloprost; Intermittent Claudication; Leg; Meta-Analysis as Topic; Middle Aged; Multicenter Studies as Topic; Myocardial Infarction; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Thrombectomy; Ticlopidine; Time Factors; Vitamin K | 2003 |
The IST registry.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Beta Particles; Brachytherapy; Clopidogrel; Coronary Restenosis; Drug Therapy, Combination; Gamma Rays; Germany; Humans; Internet; Placebos; Platelet Aggregation Inhibitors; Radiotherapy Dosage; Randomized Controlled Trials as Topic; Registries; Stents; Thrombosis; Ticlopidine; Time Factors | 2002 |
[Off-label use of clopidogrel after coronary stent implantation in Germany: optional or mandatory?].
Topics: Aspirin; Clopidogrel; Coronary Restenosis; Coronary Stenosis; Drug Approval; Drug Costs; Drug Prescriptions; Drug Therapy, Combination; Drugs, Investigational; Financing, Personal; Germany; Humans; National Health Programs; Randomized Controlled Trials as Topic; Stents; Ticlopidine; Treatment Outcome | 2003 |
A technique for type 4a coronary bifurcation lesions: initial results and 6-month clinical evaluation.
Topics: Aspirin; Blood Vessel Prosthesis Implantation; Clopidogrel; Coronary Angiography; Coronary Disease; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Treatment Outcome | 2003 |
Synergistic antiplatelet effects of clopidogrel and aspirin detected with the PFA-100 in stroke patients.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Stroke; Ticlopidine | 2003 |
Adherence to secondary stroke prevention strategies--results from the German Stroke Data Bank.
Topics: Administration, Oral; Anticoagulants; Aspirin; Clopidogrel; Databases as Topic; Female; Follow-Up Studies; Germany; Humans; Male; Patient Compliance; Platelet Aggregation Inhibitors; Prospective Studies; Secondary Prevention; Stroke; Ticlopidine; Time Factors | 2003 |
[Clearly superior in acute coronary syndrome. Helps aggressive platelet inhibition even after stroke?].
Topics: Acute Disease; Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Humans; Myocardial Ischemia; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Syndrome; Ticlopidine; Time Factors | 2003 |
Clopidogrel and percutaneous coronary interventions.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Administration Schedule; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2003 |
Clopidogrel and percutaneous coronary interventions.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Administration Schedule; Humans; Platelet Aggregation Inhibitors; Risk; Ticlopidine | 2003 |
Clopidogrel and percutaneous coronary interventions.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Administration Schedule; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2003 |
Clopidogrel and percutaneous coronary interventions.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Diabetes Mellitus; Drug Administration Schedule; Humans; Platelet Aggregation Inhibitors; Risk; Ticlopidine | 2003 |
Clopidogrel and percutaneous coronary interventions.
Topics: Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Administration Schedule; Humans; Myocardial Ischemia; Platelet Aggregation Inhibitors; Ticlopidine | 2003 |
[Secondary prevention after ischemic stroke].
Topics: Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Cerebral Infarction; Clinical Trials as Topic; Clopidogrel; Evidence-Based Medicine; Fibrinolytic Agents; Humans; Risk; Secondary Prevention; Ticlopidine | 2003 |
Coronary artery bypass graft surgery in patients with recent exposure to clopidogrel and aspirin therapy.
Topics: Aspirin; Blood Component Transfusion; Blood Loss, Surgical; Clopidogrel; Coronary Artery Bypass; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2003 |
The use of the X-Sizer transluminal extraction catheter as an adjunct to stenting of occluded saphenous vein grafts.
Topics: Abciximab; Aged; Antibodies, Monoclonal; Aspirin; Blood Vessel Prosthesis Implantation; Catheters, Indwelling; Clopidogrel; Combined Modality Therapy; Coronary Angiography; Female; Graft Occlusion, Vascular; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Platelet Aggregation Inhibitors; Saphenous Vein; Stents; Ticlopidine | 2003 |
Antiplatelet agents. European perspective.
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Europe; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2003 |
Antiplatelet drugs.
Topics: Aspirin; Clopidogrel; Dipyridamole; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Primary Prevention; Pulmonary Embolism; Thrombosis; Ticlopidine; Venous Thrombosis | 2003 |
Increased blood product use among coronary artery bypass patients prescribed preoperative aspirin and clopidogrel.
Topics: Aged; Aspirin; Clopidogrel; Cohort Studies; Coronary Artery Bypass; Drug Therapy, Combination; Erythrocyte Transfusion; Female; Hematocrit; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Transfusion; Retrospective Studies; Statistics as Topic; Ticlopidine | 2003 |
Atorvastatin-clopidogrel interaction.
Topics: Aspirin; Atorvastatin; Clinical Trials as Topic; Clopidogrel; Confounding Factors, Epidemiologic; Drug Interactions; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Platelet Aggregation Inhibitors; Pyrroles; Ticlopidine | 2003 |
Resistance to thienopyridines: clinical detection of coronary stent thrombosis by monitoring of vasodilator-stimulated phosphoprotein phosphorylation.
Topics: Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Case-Control Studies; Cell Adhesion Molecules; Chi-Square Distribution; Clopidogrel; Coronary Restenosis; Coronary Stenosis; Coronary Thrombosis; Drug Resistance; Female; Flow Cytometry; Humans; Male; Microfilament Proteins; Middle Aged; Monitoring, Physiologic; Phosphoproteins; Pilot Projects; Platelet Aggregation Inhibitors; Premedication; Probability; Prospective Studies; Reference Values; Risk Assessment; Severity of Illness Index; Statistics, Nonparametric; Stents; Ticlopidine; Treatment Outcome | 2003 |
[Diagnosis and therapy of aneurysms of the atrial septum].
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Echocardiography; Echocardiography, Transesophageal; Heart Aneurysm; Heart Atria; Heart Septum; Humans; Incidental Findings; Intracranial Embolism; Risk; Ticlopidine | 2003 |
Clopidogrel plus long-term aspirin after femoro-popliteal stenting. The CLAFS project: 1- and 2-year results.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Angiography; Angioplasty, Balloon; Anticoagulants; Arterial Occlusive Diseases; Aspirin; Blood Flow Velocity; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Female; Femoral Artery; Fibrinolysis; Follow-Up Studies; Heparin, Low-Molecular-Weight; Humans; Long-Term Care; Male; Middle Aged; Popliteal Artery; Prosthesis Failure; Retrospective Studies; Secondary Prevention; Stents; Tantalum; Ticlopidine; Treatment Outcome; Ultrasonography, Doppler, Color; Ultrasonography, Doppler, Duplex | 2004 |
[Acute coronary syndrome. The second platelet inhibitor is self-paid].
Topics: Acute Disease; Angina, Unstable; Aspirin; Clinical Trials as Topic; Clopidogrel; Cost-Benefit Analysis; Drug Therapy, Combination; Electrocardiography; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine | 2003 |
[Effects of antiaggregants on concentration of plasma cytokines in patients with acute coronary syndrome].
Topics: Acute Disease; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Cytokines; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine | 2003 |
Clopidogrel before urgent coronary artery bypass graft.
Topics: Acute Disease; Adrenergic beta-Antagonists; Aged; Anticoagulants; Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Disease; Emergency Treatment; Female; Heparin; Humans; Intra-Aortic Balloon Pumping; Male; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Premedication; Switzerland; Syndrome; Ticlopidine; Treatment Outcome | 2003 |
A prospective study on ultrasound-guided compression therapy or thrombin injection for treatment of iatrogenic false aneurysms in patients receiving full-dose anti-platelet therapy.
Topics: Aged; Aged, 80 and over; Aneurysm, False; Angioplasty, Balloon, Coronary; Arteriovenous Fistula; Aspirin; Cardiac Catheterization; Catheterization, Peripheral; Clopidogrel; Female; Femoral Artery; Humans; Iatrogenic Disease; Injections, Intra-Arterial; Male; Middle Aged; Platelet Aggregation Inhibitors; Pressure; Prospective Studies; Thrombin; Ticlopidine; Transducers; Treatment Outcome; Ultrasonography, Doppler, Color | 2003 |
Timing of anti-platelet effect after oral aspirin administration in patients with sympathetic excitement.
Topics: Aged; Aspirin; Blood Platelets; Collagen; Coronary Angiography; Humans; Male; Middle Aged; Myocardial Infarction; Osmolar Concentration; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Sympathetic Nervous System; Ticlopidine; Time Factors | 2003 |
Regression of intracardiac heparin-induced thrombosis after aortic root surgery.
Topics: Aged; Anticoagulants; Aortic Aneurysm, Thoracic; Aspirin; Blood Vessel Prosthesis; Clopidogrel; Drug Therapy, Combination; Echocardiography, Transesophageal; Follow-Up Studies; Heart Diseases; Heparin, Low-Molecular-Weight; Humans; Risk Assessment; Severity of Illness Index; Thrombocytopenia; Thrombosis; Ticlopidine; Treatment Outcome; Warfarin | 2003 |
Subintimal angioplasty of long superficial femoral artery occlusions.
Topics: Angioplasty; Arterial Occlusive Diseases; Aspirin; Clopidogrel; Female; Femoral Artery; Fibrinolytic Agents; Follow-Up Studies; Humans; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Postoperative Care; Proportional Hazards Models; Stents; Ticlopidine; Time Factors; Treatment Outcome; Vascular Patency; Warfarin | 2003 |
Clopidogrel is associated with better in-hospital and 30-day outcomes than ticlopidine after coronary stenting.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Cause of Death; Clopidogrel; Coronary Stenosis; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Hospital Mortality; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Premedication; Product Surveillance, Postmarketing; Retrospective Studies; Stents; Survival Analysis; Ticlopidine; Treatment Outcome | 2003 |
[Long-term therapy with clopidogrel in combination with ASA significantly reduces risk of death, myocardial infarct or stroke].
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Humans; Multicenter Studies as Topic; Myocardial Infarction; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk; Stroke; Ticlopidine | 2003 |
Qualitative platelet defect and thrombohaemorrhagic complications in a patient with polycythaemia vera. Case 10.
Topics: Aged; Aspirin; Blood Platelet Disorders; Clopidogrel; Hemorrhage; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polycythemia Vera; Thrombosis; Ticlopidine | 2003 |
Cardiology patient page. Antiplatelet therapy.
Topics: Aspirin; Blood Coagulation; Blood Platelets; Clopidogrel; Heart Diseases; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombosis; Ticlopidine | 2003 |
Intracoronary radiation to treat in-stent restenosis in six cardiac transplant patients.
Topics: Abciximab; Adult; Aged; Antibodies, Monoclonal; Arteries; Aspirin; Blood Vessel Prosthesis Implantation; Brachytherapy; California; Clopidogrel; Coronary Angiography; Coronary Restenosis; Coronary Vessels; Female; Follow-Up Studies; Heart Transplantation; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Platelet Aggregation Inhibitors; Reoperation; Stents; Ticlopidine; Treatment Outcome | 2003 |
Ask the doctor. Almost every day I read how important it is for people with heart disease to take an aspirin. Unfortunately, I am allergic to aspirin. There must be others with the same problem. Are there viable alternatives to aspirin? It's discouraging
Topics: Aspirin; Clopidogrel; Drug Hypersensitivity; Fatty Acids, Omega-3; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine | 2003 |
Clopidogrel in acute coronary syndromes: can the cost effectiveness improve?
Topics: Acute Disease; Aspirin; Clopidogrel; Coronary Disease; Cost-Benefit Analysis; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Risk; Ticlopidine; Treatment Outcome | 2003 |
High incidence of clopidogrel-associated gastrointestinal bleeding in patients with previous peptic ulcer disease.
Topics: Aged; Aspirin; Clopidogrel; Cohort Studies; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Humans; Longitudinal Studies; Male; Peptic Ulcer; Platelet Aggregation Inhibitors; Recurrence; Retrospective Studies; Risk Factors; Ticlopidine | 2003 |
[Clopidogrel should be added to aspirin for at least 1 year after percutaneous coronary interventions (CREDO) while before them its loading dose can reach 600mg (ISAR-COOL)].
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Electrocardiography; Fibrinolytic Agents; Follow-Up Studies; Humans; Placebos; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Randomized Controlled Trials as Topic; Risk Factors; Ticlopidine; Time Factors | 2003 |
[Recurrence prophylaxis for stroke patients. Which platelet inhibitor combination protects best?].
Topics: Angiotensin II Type 1 Receptor Blockers; Aspirin; Aspirin, Dipyridamole Drug Combination; Benzimidazoles; Benzoates; Clopidogrel; Delayed-Action Preparations; Dipyridamole; Drug Combinations; Humans; Middle Aged; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Secondary Prevention; Stroke; Telmisartan; Ticlopidine | 2003 |
Urgent or emergent coronary revascularization using bilateral internal thoracic artery after previous clopidogrel antiplatelet therapy.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Transfusion; Chest Tubes; Clopidogrel; Coronary Artery Bypass; Emergencies; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Reoperation; Retrospective Studies; Ticlopidine | 2003 |
Platelet inhibition strategies in percutaneous coronary intervention: competition or coopetition?
Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clopidogrel; Combined Modality Therapy; Drug Administration Schedule; Humans; Immunoglobulin Fab Fragments; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine; Tirofiban; Tyrosine | 2003 |
[Outpatient primary stent-angioplasty in symptomatic internal carotid artery stenoses].
Topics: Aged; Angiography; Angioplasty, Balloon; Anticoagulants; Aspirin; Carotid Artery, Internal; Carotid Stenosis; Clopidogrel; Drug Therapy, Combination; Embolism; Female; Fibrinolytic Agents; Follow-Up Studies; Heparin; Humans; Male; Middle Aged; Outpatients; Patient Selection; Platelet Aggregation Inhibitors; Prostheses and Implants; Risk Factors; Stents; Ticlopidine; Time Factors | 2003 |
Racial disparities in receipt of secondary stroke prevention agents among US nursing home residents.
Topics: Aged; Anticoagulants; Aspirin; Databases, Factual; Dipyridamole; Drug Therapy, Combination; Drug Utilization Review; Health Services Accessibility; Humans; Nursing Homes; Prejudice; Preventive Medicine; Racial Groups; Risk Reduction Behavior; Secondary Prevention; Stroke; Ticlopidine; United States; Warfarin | 2003 |
Influence of residual stenosis after coronary stent implantation on development of restenosis and stent thrombosis.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Coronary Angiography; Coronary Restenosis; Coronary Thrombosis; Humans; Platelet Aggregation Inhibitors; Regression Analysis; Stents; Ticlopidine | 2003 |
[PRoFESS study presented. Change in secondary prevention].
Topics: Angiotensin-Converting Enzyme Inhibitors; Aspirin; Aspirin, Dipyridamole Drug Combination; Benzimidazoles; Benzoates; Clopidogrel; Controlled Clinical Trials as Topic; Dipyridamole; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Multicenter Studies as Topic; Placebos; Platelet Aggregation Inhibitors; Recurrence; Risk; Stroke; Telmisartan; Ticlopidine; Time Factors | 2003 |
[Dual platelet inhibition with clopidogrel and ASS. Who profits from the combination?].
Topics: Acute Disease; Angina, Unstable; Aspirin; Clinical Trials as Topic; Clopidogrel; Cyclooxygenase Inhibitors; Drug Synergism; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk Factors; Stents; Stroke; Syndrome; Thrombosis; Ticlopidine | 2003 |
[Sudden edema and pain in the knee].
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Interactions; Drug Therapy, Combination; Edema; Hemorrhage; Humans; Knee Joint; Male; Pain; Platelet Aggregation Inhibitors; Radiography; Ticlopidine | 2003 |
Cost-effectiveness of newer antiplatelet drugs.
Topics: Aspirin; Clopidogrel; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2003 |
Red vs white thrombi: treating the right clot is crucial.
Topics: Aspirin; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Thrombosis; Ticlopidine | 2003 |
Regression of collateral function after recanalization of chronic total coronary occlusions: a serial assessment by intracoronary pressure and Doppler recordings.
Topics: Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Collateral Circulation; Combined Modality Therapy; Coronary Angiography; Coronary Circulation; Coronary Disease; Female; Follow-Up Studies; Heparin; Humans; Laser-Doppler Flowmetry; Male; Middle Aged; Nitroglycerin; Pressure; Recurrence; Stroke Volume; Ticlopidine; Ultrasonography | 2003 |
Platelet function under aspirin, clopidogrel, and both after ischemic stroke: a case-crossover study.
Topics: Antigens, CD; Aspirin; Biomarkers; Blood Platelets; Brain Ischemia; Clopidogrel; Cross-Over Studies; Humans; P-Selectin; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Stroke; Tetraspanin 30; Ticlopidine | 2003 |
Beta brachytherapy of an old degenerated saphenous vein graft with occlusive in-stent restenosis.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Beta Particles; Blood Vessel Prosthesis; Brachytherapy; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease; Female; Fibrinolytic Agents; Graft Occlusion, Vascular; Humans; Myocardial Infarction; Phosphorus Radioisotopes; Reoperation; Saphenous Vein; Stents; Ticlopidine; Tirofiban; Tyrosine | 2003 |
In vitro effects of clopidogrel on the platelet-subendothelium interaction, platelet thromboxane and endothelial prostacyclin production, and nitric oxide synthesis.
Topics: Adult; Aspirin; Blood Platelets; Cells, Cultured; Clopidogrel; Epoprostenol; Humans; Male; Middle Aged; Nitric Oxide; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane B2; Ticlopidine | 2004 |
Comparison of turbidimetric aggregation and in vitro bleeding time (PFA-100) for monitoring the platelet inhibitory profile of antiplatelet agents in patients undergoing stent implantation.
Topics: Abciximab; Adenosine Diphosphate; Aged; Angina Pectoris; Antibodies, Monoclonal; Aspirin; Bleeding Time; Clopidogrel; Collagen; Female; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Nephelometry and Turbidimetry; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Stents; Ticlopidine; Time Factors | 2003 |
A feasibility study of the safety and efficacy of a combined clopidogrel and aspirin regimen following off-pump coronary artery bypass grafting.
Topics: Anticoagulants; Aspirin; Clopidogrel; Coronary Artery Bypass; Drug Therapy, Combination; Feasibility Studies; Female; Follow-Up Studies; Heparin; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Prospective Studies; Stroke; Ticlopidine; Venous Thrombosis | 2003 |
Aspirin for cardiovascular disease prevention.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2004 |
Antiplatelet therapy for ischemic heart disease.
Topics: Abciximab; Angina, Unstable; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Humans; Immunoglobulin Fab Fragments; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine | 2004 |
Influence of glucose concentration on the effects of aspirin, ticlopidine and clopidogrel on platelet function and platelet-subendothelium interaction.
Topics: Adult; Aspirin; Blood Platelets; Clopidogrel; Dose-Response Relationship, Drug; Endothelium, Vascular; Glucose; Humans; Male; Middle Aged; Platelet Aggregation; Ticlopidine | 2004 |
Catheter based intracoronary brachytherapy leads to increased platelet activation.
Topics: Angina Pectoris; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Blood Platelets; Brachytherapy; Clopidogrel; Coronary Restenosis; Equipment Failure; Female; Flow Cytometry; Heparin; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2004 |
Benefit of clopidogrel over aspirin is amplified in patients with a history of ischemic events.
Topics: Aged; Arteriosclerosis; Aspirin; Brain Ischemia; Clopidogrel; Databases, Factual; Female; Hospitalization; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Proportional Hazards Models; Randomized Controlled Trials as Topic; Risk; Secondary Prevention; Stroke; Survival Rate; Ticlopidine; Treatment Outcome | 2004 |
[Must platelet aggregation inhibitors be discontinued before surgery?].
Topics: Angiography; Aspirin; Blood Loss, Surgical; Clopidogrel; Humans; Pacemaker, Artificial; Platelet Aggregation Inhibitors; Risk Factors; Thromboembolism; Ticlopidine | 2004 |
Incidence, mechanism, predictors, and long-term prognosis of late stent malapposition after bare-metal stent implantation.
Topics: Aged; Aspirin; Atherectomy, Coronary; Catheterization; Cilostazol; Combined Modality Therapy; Coronary Angiography; Coronary Restenosis; Coronary Stenosis; Coronary Thrombosis; Death, Sudden, Cardiac; Disease-Free Survival; Elective Surgical Procedures; Female; Follow-Up Studies; Foreign-Body Migration; Humans; Incidence; Korea; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Prognosis; Retrospective Studies; Stents; Tetrazoles; Ticlopidine; Treatment Outcome; Ultrasonography, Interventional | 2004 |
Increased platelet CD63 and P-selectin expression persist in atherosclerotic ischemic stroke.
Topics: Adenosine Diphosphate; Aged; Anticoagulants; Antigens, CD; Aspirin; Blood Platelets; Brain Ischemia; Clopidogrel; Collagen; Female; Flow Cytometry; Heparin; Humans; Intracranial Arteriosclerosis; Lipids; Male; Middle Aged; P-Selectin; Patient Selection; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Glycoprotein GPIb-IX Complex; Platelet Membrane Glycoproteins; Stroke; Tetraspanin 30; Ticlopidine; Time Factors | 2004 |
Percutaneous coronary intervention in a patient with immune thrombocytopenia purpura.
Topics: Aged; Angioplasty, Balloon; Aspirin; Clopidogrel; Coronary Angiography; Coronary Stenosis; Eptifibatide; Humans; Male; Peptides; Platelet Aggregation Inhibitors; Purpura, Thrombocytopenic, Idiopathic; Stents; Ticlopidine | 2004 |
When guidelines collide...
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Stents; Ticlopidine; Warfarin | 2004 |
Safety and efficacy of aspirin, clopidogrel, and warfarin after coronary stent placement in patients with an indication for anticoagulation.
Topics: Aged; Aged, 80 and over; Angina, Unstable; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Retrospective Studies; Stents; Ticlopidine; Warfarin | 2004 |
[Efficacy and safety of treatment of acute ischemic stroke with glycoprotein IIb/IIIa receptor blocker in routine clinical practice].
Topics: Adult; Aged; Anticoagulants; Aspirin; Brain; Brain Ischemia; Carotid Arteries; Clopidogrel; Drug Therapy, Combination; Echocardiography, Transesophageal; Eptifibatide; Female; Heparin; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Peptides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Retrospective Studies; Stroke; Ticlopidine; Tirofiban; Tomography, X-Ray Computed; Tyrosine; Ultrasonography, Doppler | 2004 |
Inhibition of platelet aggregation by aspirin progressively decreases in long-term treated patients.
Topics: Adenosine Diphosphate; Aged; Aspirin; Collagen; Female; Humans; Longitudinal Studies; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2004 |
Aspirin resistance is associated with a high incidence of myonecrosis after non-urgent percutaneous coronary intervention despite clopidogrel pretreatment.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Creatine Kinase; Creatine Kinase, MB Form; Drug Resistance; Female; Humans; Incidence; Isoenzymes; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Postoperative Period; Sex Factors; Ticlopidine; Troponin I | 2004 |
Limited early antiplatelet effect of 300 mg clopidogrel in patients with aspirin therapy undergoing percutaneous coronary interventions.
Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Disease; Coronary Thrombosis; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2004 |
If there's smoke, is there fire?
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Endarterectomy, Carotid; Endpoint Determination; Humans; Intracranial Embolism; Platelet Aggregation Inhibitors; Postoperative Complications; Randomized Controlled Trials as Topic; Research Design; Ticlopidine; Ultrasonography, Doppler, Transcranial | 2004 |
Guidelines on the management of secondary prophylaxis of vascular events in stable patients in primary care.
Topics: Acute Disease; Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Bypass; Dipyridamole; Endarterectomy, Carotid; Humans; Life Style; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Secondary Prevention; Stents; Ticlopidine; Treatment Outcome | 2004 |
Late stent thrombosis (> 1 year) following clopidogrel withdrawal after brachytherapy treatment: need to assess aspirin resistance?
Topics: Adult; Angioplasty, Balloon, Coronary; Aspirin; Blood Vessel Prosthesis Implantation; Brachytherapy; Clopidogrel; Combined Modality Therapy; Coronary Angiography; Coronary Stenosis; Coronary Thrombosis; Drug Resistance; Graft Occlusion, Vascular; Humans; Male; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Time Factors | 2004 |
Resistance to antiplatelet drugs: is it real or relevant?
Topics: Angioplasty, Balloon, Coronary; Aspirin; Blood Vessel Prosthesis Implantation; Brachytherapy; Clopidogrel; Coronary Stenosis; Coronary Thrombosis; Drug Resistance; Graft Occlusion, Vascular; Humans; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Time Factors | 2004 |
2 drugs team up for protection. Old standby joins relative newcomer to battle heart disease.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine | 2003 |
"Super aspirin" cuts risks after multiple cardiac events.
Topics: Aspirin; Clopidogrel; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Secondary Prevention; Stroke; Ticlopidine | 2004 |
Detection of acutely impaired microvascular reperfusion after infarct angioplasty with magnetic resonance imaging.
Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Aspirin; Clopidogrel; Combined Modality Therapy; Coronary Circulation; Female; Heart Ventricles; Heparin; Humans; Immunoglobulin Fab Fragments; Magnetic Resonance Imaging; Male; Microcirculation; Middle Aged; Myocardial Infarction; Myocardial Reperfusion; Prospective Studies; Ticlopidine; Tirofiban; Treatment Outcome; Tyrosine; Ventricular Function, Left | 2004 |
Antiplatelet therapy for ischemic heart disease.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Cost-Benefit Analysis; Drug Therapy, Combination; Humans; Myocardial Infarction; Myocardial Ischemia; Platelet Aggregation Inhibitors; Ticlopidine | 2004 |
Basilar artery to bilateral posterior cerebral artery 'Y stenting' for endovascular reconstruction of wide-necked basilar apex aneurysms: report of three cases.
Topics: Adult; Aged; Aspirin; Cerebral Angiography; Clopidogrel; Female; Follow-Up Studies; Humans; Intracranial Aneurysm; Platelet Aggregation Inhibitors; Posterior Cerebral Artery; Stents; Ticlopidine; Treatment Outcome | 2004 |
By the way, doctor. I'm 74 and in good health with no apparent heart problems. Because I am allergic to aspirin, it has been suggested that I take Plavix. Your thoughts?
Topics: Aged; Aspirin; Clopidogrel; Drug Hypersensitivity; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2004 |
Serial changes in platelet activation in patients after ischemic stroke: role of pharmacodynamic modulation.
Topics: Aged; Anticoagulants; Aspirin; Blood Platelets; Clopidogrel; Female; Humans; Male; Middle Aged; P-Selectin; Platelet Activation; Stroke; Ticlopidine; Warfarin | 2004 |
PlA polymorphism and platelet reactivity following clopidogrel loading dose in patients undergoing coronary stent implantation.
Topics: Abciximab; Adenosine Diphosphate; Aged; Amino Acid Substitution; Antibodies, Monoclonal; Aspirin; Blood Platelets; Clopidogrel; Coronary Thrombosis; Dose-Response Relationship, Drug; Female; Gene Expression Regulation; Heterozygote; Homozygote; Humans; Immunoglobulin Fab Fragments; Integrin beta3; Male; Middle Aged; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Polymorphism, Genetic; Stents; Ticlopidine; Treatment Outcome | 2004 |
Clopidogrel versus aspirin for secondary prophylaxis of vascular events: a cost-effectiveness analysis.
Topics: Aspirin; Clopidogrel; Cost-Benefit Analysis; Fibrinolytic Agents; Humans; Markov Chains; Middle Aged; Platelet Aggregation Inhibitors; Sensitivity and Specificity; Ticlopidine; Vascular Diseases | 2004 |
Aspirin or clopidogrel for secondary prevention of cardiovascular events: is there a winner?
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2004 |
Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction.
Topics: Adenosine Diphosphate; Aged; Aspirin; Biotransformation; Clopidogrel; Combined Modality Therapy; Coronary Artery Disease; Coronary Restenosis; Coronary Thrombosis; Drug Resistance; Drug Therapy, Combination; Epinephrine; Eptifibatide; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Prodrugs; Prospective Studies; Purinergic P2 Receptor Antagonists; Recurrence; Risk; Smoking; Stents; Ticlopidine; Treatment Outcome | 2004 |
Long-term management of patients with unstable angina and non-ST-elevation MI.
Topics: Angina, Unstable; Aspirin; Clopidogrel; Evidence-Based Medicine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Myocardial Infarction; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Ticlopidine; Treatment Outcome | 2004 |
Different treatments and outcomes of consecutive patients with non-ST-elevation myocardial infarction depending on initial electrocardiographic changes (results of the Acute Coronary Syndromes [ACOS] Registry).
Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Angioplasty, Balloon, Coronary; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Clopidogrel; Coronary Disease; Coronary Vessels; Drug Utilization; Electrocardiography; Female; Germany; Hospital Mortality; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Multivariate Analysis; Myocardial Infarction; Outcome and Process Assessment, Health Care; Platelet Aggregation Inhibitors; Recurrence; Registries; Stroke Volume; Ticlopidine; Ventricular Dysfunction, Left | 2004 |
[Antithrombotic treatment of acute coronary syndrome].
Topics: Anticoagulants; Aspirin; Clopidogrel; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Thrombolytic Therapy; Ticlopidine | 2004 |
Clopidogrel resistance: a new chapter in a fast-moving story.
Topics: Angioplasty; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coronary Disease; Dose-Response Relationship, Drug; Drug Resistance; Drug Therapy, Combination; Eptifibatide; Heparin; Humans; Peptides; Platelet Aggregation Inhibitors; Stents; Thromboxane A2; Ticlopidine; Treatment Outcome | 2004 |
Antifibrinolytics may be cost saving among recent recipients of combined acetylsalicylic acid and clopidogrel who undergo coronary artery bypass graft surgery.
Topics: Antifibrinolytic Agents; Aspirin; Clopidogrel; Coronary Artery Bypass; Cost-Benefit Analysis; Drug Costs; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine | 2004 |
[New antiplatelet agents (platelet receptor blockers): has aspirin come out of place?].
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Thrombosis; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Secondary Prevention; Thrombophilia; Ticlopidine; Treatment Outcome | 2004 |
[What should one pay attention to during surgery shortly after brachytherapy with coated stents?].
Topics: Angioplasty, Balloon, Coronary; Aspirin; Brachytherapy; Clopidogrel; Contraindications; Coronary Thrombosis; Elective Surgical Procedures; Emergency Treatment; Humans; Platelet Aggregation Inhibitors; Risk Factors; Stents; Ticlopidine; Time Factors | 2004 |
Building evidence for early initiation of clopidogrel loading in non-ST-segment elevation acute coronary syndromes: going past the American College of Cardiology/American Heart Association guidelines.
Topics: Angina, Unstable; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Therapy, Combination; Electrocardiography; Emergency Service, Hospital; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Ticlopidine | 2004 |
Multivessel distal sutureless off-pump coronary artery bypass grafting procedure using magnetic connectors.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Bypass, Off-Pump; Coronary Restenosis; Coronary Stenosis; Equipment Design; Humans; Internal Mammary-Coronary Artery Anastomosis; Magnetics; Platelet Aggregation Inhibitors; Postoperative Complications; Thrombosis; Ticlopidine | 2004 |
A critical appraisal of the CURE trial: role of clopidogrel in non-ST-segment elevation acute coronary syndromes.
Topics: Aspirin; Clopidogrel; Confidence Intervals; Humans; Myocardial Infarction; Randomized Controlled Trials as Topic; Stroke; Ticlopidine | 2004 |
Effective antiplatelet therapy does not prolong transgenic pig to baboon cardiac xenograft survival.
Topics: Animals; Animals, Genetically Modified; Antigens, CD; Aspirin; Clopidogrel; Graft Rejection; Graft Survival; Heart Transplantation; Humans; Membrane Cofactor Protein; Membrane Glycoproteins; Papio anubis; Platelet Aggregation; Platelet Aggregation Inhibitors; Swine; Ticlopidine; Time Factors; Transplantation, Heterologous | 2004 |
There is no evidence that the benefit of clopidogrel over aspirin is amplified in patients with a history of ischemic events.
Topics: Arteriosclerosis; Aspirin; Brain Ischemia; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Prognosis; Risk; Ticlopidine | 2004 |
Platelet function predicts myocardial damage in patients with acute myocardial infarction.
Topics: Abciximab; Adenosine Diphosphate; Aged; Antibodies, Monoclonal; Anticoagulants; Aspirin; Cardiovascular Agents; Clopidogrel; Collagen; Comorbidity; Eptifibatide; Female; Humans; Immunoglobulin Fab Fragments; Leukocyte Count; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Myocardium; Necrosis; Peptides; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prospective Studies; Ticlopidine; Tirofiban; Tyrosine; von Willebrand Factor | 2004 |
Combined aspirin and clopidogrel in cataract surgical patients: a new risk factor for ocular haemorrhage?
Topics: Aged; Aspirin; Cataract Extraction; Clopidogrel; Drug Therapy, Combination; Eye Hemorrhage; Humans; Male; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine | 2004 |
[Cardiovascular pharmacology].
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Fatty Acids, Omega-3; Fibrinolytic Agents; Graft Occlusion, Vascular; Humans; Myocardial Ischemia; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine | 2004 |
Perioperative hemorrhage and combined clopidogrel and aspirin therapy.
Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Drug Combinations; Endarterectomy, Carotid; Female; Goiter, Nodular; Hemorrhage; Humans; Intraoperative Complications; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Thyroidectomy; Ticlopidine; Tomography, X-Ray Computed | 2004 |
Elevations in troponin I after percutaneous coronary interventions are associated with abnormal tissue-level perfusion in high-risk patients with non-ST-segment-elevation acute coronary syndromes.
Topics: Abciximab; Acute Disease; Aged; Angina Pectoris; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Biomarkers; Clopidogrel; Combined Modality Therapy; Coronary Angiography; Coronary Circulation; Electrocardiography; Female; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Myocardial Ischemia; Myocardial Reperfusion Injury; Platelet Aggregation Inhibitors; Prospective Studies; Risk; Ticlopidine; Tirofiban; Troponin I; Tyrosine; Ultrasonography | 2004 |
[Urgent or emergent coronary revascularization using bilateral internal thoracic artery after previous clopidogrel antiplatelet therapy].
Topics: Aged; Aspirin; Blood Transfusion; Clopidogrel; Coronary Artery Bypass; Data Interpretation, Statistical; Emergencies; Female; Humans; Intensive Care Units; Length of Stay; Male; Middle Aged; Platelet Aggregation Inhibitors; Preoperative Care; Respiration, Artificial; Retrospective Studies; Thoracic Arteries; Ticlopidine | 2004 |
[Secondary prevention of TIA and stroke. How much must thrombocytes not be inhibited?].
Topics: Aspirin; Cerebral Infarction; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Ischemic Attack, Transient; Platelet Aggregation; Platelet Aggregation Inhibitors; Risk; Secondary Prevention; Ticlopidine | 2004 |
[For which patient ASS, clopidogrel or dipyridamole? (interview by Dr. Med. Dirk Einecke)].
Topics: Aspirin; Cerebral Infarction; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Secondary Prevention; Ticlopidine; Treatment Outcome | 2004 |
[How does it work? Coronary stent implantation].
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Restenosis; Coronary Stenosis; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2004 |
Effects of a novel platelet nitric oxide donor (LA816), aspirin, clopidogrel, and combined therapy in inhibiting flow- and lesion-dependent thrombosis in the porcine ex vivo model.
Topics: Adenosine Diphosphate; Amino Acids; Animals; Aspirin; Benzoates; Blood Pressure; Clopidogrel; Collagen; Cyclooxygenase Inhibitors; Drug Evaluation; Drug Therapy, Combination; Fibrinolytic Agents; Free Radical Scavengers; Guanylate Cyclase; Heart Rate; Hemorheology; Imidazoles; Membrane Proteins; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Oxadiazoles; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Quinoxalines; Random Allocation; Receptors, Purinergic P2Y12; rhoA GTP-Binding Protein; Sus scrofa; Thrombosis; Ticlopidine | 2004 |
Platelet-active drugs: the relationships among dose, effectiveness, and side effects: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.
Topics: Administration, Oral; Aspirin; Clopidogrel; Coronary Thrombosis; Evidence-Based Medicine; Humans; Myocardial Revascularization; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Randomized Controlled Trials as Topic; Risk Factors; Thromboembolism; Ticlopidine; Treatment Outcome | 2004 |
[Peridural injections during acetylsalicylic acid and clopidogrel therapy?].
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Hemorrhage; Humans; Injections, Epidural; Intervertebral Disc Displacement; Middle Aged; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2004 |
Late coronary thrombosis after drug-eluting stent: stent vs patient-driven prescription of aspirin-clopidogrel combination.
Topics: Aspirin; Clopidogrel; Coronary Thrombosis; Drug Therapy, Combination; Female; Humans; Middle Aged; Practice Guidelines as Topic; Stents; Ticlopidine; Time Factors | 2004 |
[Clopidogrel protection is not increased further by ASS!].
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Ischemic Attack, Transient; Middle Aged; Placebos; Platelet Aggregation Inhibitors; Recurrence; Risk Factors; Stroke; Ticlopidine | 2004 |
[Clopidogrel as basic therapy in high-risk stroke patients].
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Hemorrhage; Humans; Life Style; Meta-Analysis as Topic; Multicenter Studies as Topic; Placebos; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Ticlopidine; Time Factors | 2004 |
Coronary spasm in a 59-yr-old woman with hyperventilation.
Topics: Alkalosis, Respiratory; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Antihypertensive Agents; Aspirin; Cardiac Catheterization; Clopidogrel; Coronary Artery Disease; Coronary Vasospasm; Diagnosis, Differential; Diltiazem; Electrocardiography; Female; Heparin; Humans; Hyperventilation; Hyponatremia; Middle Aged; Platelet Aggregation Inhibitors; Schizophrenia; Ticlopidine; Water Intoxication | 2004 |
Should the MATCH results be extrapolated to all stroke patients and affect ongoing trials evaluating clopidogrel plus aspirin?
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2004 |
Progressive cervicocranial arteriopathy with dilatations and stenoses: case report.
Topics: Adult; Arterial Occlusive Diseases; Aspirin; Basilar Artery; Carotid Artery Diseases; Carotid Artery, Internal; Cerebral Angiography; Clopidogrel; Female; Humans; Intracranial Aneurysm; Platelet Aggregation Inhibitors; Subarachnoid Hemorrhage; Ticlopidine | 2004 |
[Current pharmacological principles to inhibit platelet function and their clinical implications. Focus on clopidogrel].
Topics: Aspirin; Clopidogrel; Embolism, Cholesterol; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine | 2004 |
[Antiplatelet strategies in the acute and chronic therapy of cardiovascular disease].
Topics: Aspirin; Clopidogrel; Coronary Thrombosis; Drug Therapy, Combination; Humans; Long-Term Care; Myocardial Infarction; Platelet Activation; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine | 2004 |
[Antiplatelet therapy in patients with peripheral arterial disease (PAD)].
Topics: Arterial Occlusive Diseases; Aspirin; Cause of Death; Cerebral Infarction; Clopidogrel; Coronary Artery Disease; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Survival Rate; Ticlopidine | 2004 |
[Secondary prevention of stroke with antiplatelet drugs].
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Platelet Activation; Platelet Aggregation Inhibitors; Risk; Secondary Prevention; Stroke; Survival Rate; Ticlopidine | 2004 |
[Do low risk patients undergoing percutaneous coronary intervention after pretreatment with clopidogrel need abciximab infusion? Results of ISAR-REACT study].
Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Aspirin; Clopidogrel; Coronary Angiography; Coronary Disease; Humans; Immunoglobulin Fab Fragments; Infusions, Parenteral; Placebos; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Ticlopidine; Time Factors | 2004 |
Evolution of spontaneous atherosclerotic plaque rupture with medical therapy: long-term follow-up with intravascular ultrasound.
Topics: Aged; Aspirin; Biomarkers; Clopidogrel; Coronary Artery Disease; Disease Progression; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation Inhibitors; Rupture, Spontaneous; Ticlopidine; Troponin I; Ultrasonography, Interventional | 2004 |
[Attack on many vascular fronts. Atherothrombosis trouble seldom comes alone].
Topics: Aged; Arterial Occlusive Diseases; Arteriosclerosis; Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Female; Humans; Intracranial Arteriosclerosis; Male; Myocardial Infarction; Platelet Activation; Platelet Aggregation Inhibitors; Ticlopidine | 2004 |
[Patients with arterial occlusive disease die of myocardial infarct or stroke. The dangerous sisters: arterial occlusive disease and coronary heart disease].
Topics: Aged; Arterial Occlusive Diseases; Aspirin; Cause of Death; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Humans; Multicenter Studies as Topic; Myocardial Infarction; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Prognosis; Risk Factors; Stroke; Ticlopidine | 2004 |
[Combination is standard. Dual thrombocyte function inhibition in acute coronary syndrome].
Topics: Angina, Unstable; Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Secondary Prevention; Ticlopidine | 2004 |
[Interview with Prof. Dr. H. J. Rupprecht about secondary prevention: what is the optimal thrombocyte function inhibition?].
Topics: Angina, Unstable; Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Long-Term Care; Myocardial Infarction; Platelet Activation; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Secondary Prevention; Syndrome; Ticlopidine | 2004 |
[Secondary prevention after ischemic stroke. High risk patients need special protection].
Topics: Arteriosclerosis; Aspirin; Cerebral Infarction; Clinical Trials as Topic; Clopidogrel; Humans; Intracranial Arteriosclerosis; Long-Term Care; Platelet Aggregation Inhibitors; Secondary Prevention; Ticlopidine; Treatment Outcome | 2004 |
[Primary and secondary prevention of stroke. Prevention is better than healing].
Topics: Aged; Aspirin; Cerebral Infarction; Clinical Trials as Topic; Clopidogrel; Combined Modality Therapy; Drug Therapy, Combination; Embolism, Cholesterol; Humans; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Risk Factors; Secondary Prevention; Ticlopidine | 2004 |
Antiplatelet therapy in non-ST-segment elevation acute coronary syndromes.
Topics: Adrenergic beta-Antagonists; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Electrocardiography; Eptifibatide; Heparin; Humans; Male; Middle Aged; Myocardial Ischemia; Nitroglycerin; Peptides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Risk Assessment; Stents; Ticlopidine; Vasodilator Agents | 2004 |
Clinical and angiographic outcome after interventional treatment of the iliac arteries with a new carbofilm coated stent: preliminary results.
Topics: Administration, Oral; Aged; Aged, 80 and over; Angiography; Anticoagulants; Arterial Occlusive Diseases; Arteriosclerosis; Aspirin; Carbon; Clopidogrel; Constriction, Pathologic; Female; Fibrinolytic Agents; Follow-Up Studies; Heparin; Humans; Iliac Artery; Injections, Intravenous; Male; Middle Aged; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Prospective Studies; Risk Factors; Stents; Ticlopidine; Time Factors; Treatment Outcome; Vascular Patency | 2004 |
Clopidogrel and postoperative bleeding.
Topics: Aprotinin; Aspirin; Blood Transfusion; Cardiopulmonary Bypass; Clopidogrel; Coronary Artery Bypass; Coronary Disease; Extracorporeal Circulation; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Prospective Studies; Stents; Ticlopidine; Time Factors | 2004 |
Does clopidogrel increase blood loss following coronary artery bypass surgery?
Topics: Aged; Aspirin; Blood Loss, Surgical; Blood Transfusion; Clopidogrel; Coronary Artery Bypass; Critical Care; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Emergencies; Female; Humans; Intensive Care Units; Length of Stay; London; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Postoperative Complications; Postoperative Hemorrhage; Premedication; Prospective Studies; Risk Factors; Ticlopidine | 2004 |
Severe stenosis of anastomoses by using the symmetry aortic connector system.
Topics: Aged; Angina, Unstable; Anticoagulants; Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Artery Bypass, Off-Pump; Coronary Restenosis; Equipment Design; Female; Humans; Hyperplasia; Male; Nickel; Reoperation; Saphenous Vein; Thoracic Arteries; Ticlopidine; Titanium; Tunica Intima; Ultrasonography | 2004 |
Subclavian stenosis/occlusion in patients with subclavian steal and previous bypass of internal mammary interventricular anterior artery: medical or surgical treatment?
Topics: Aged; Angioplasty; Aspirin; Constriction, Pathologic; Female; Humans; Internal Mammary-Coronary Artery Anastomosis; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Stents; Subclavian Steal Syndrome; Ticlopidine | 2004 |
Antiplatelet therapy.
Topics: Aged; Aspirin; Clopidogrel; Dipyridamole; Drug Interactions; Humans; Myocardial Infarction; Patient Selection; Platelet Aggregation Inhibitors; Stroke; Thromboembolism; Ticlopidine | 2004 |
I've been taking aspirin daily for 25 years, and clopidogrel fro several years. In spite of this, I've had a number of heart attacks. You reported recently on people who can't benefit from aspirin, and I think I may be one of them. What should I do?
Topics: Aspirin; Blood Coagulation Disorders; Clopidogrel; Drug Resistance; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine | 2004 |
Spinal anaesthesia despite combined clopidogrel and aspirin therapy in a patient awaiting lung transplantation: effects of platelet transfusion on clotting tests.
Topics: Anesthesia, Spinal; Aspirin; Blood Coagulation; Clopidogrel; Female; Humans; Lung Diseases, Obstructive; Lung Transplantation; Middle Aged; Platelet Aggregation Inhibitors; Platelet Transfusion; Ticlopidine | 2005 |
Concordance between clopidogrel use and prescribing guidelines.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Australia; Clopidogrel; Cohort Studies; Coronary Artery Disease; Cost-Benefit Analysis; Cross-Sectional Studies; Drug Prescriptions; Drug Utilization Review; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Practice Patterns, Physicians'; Ticlopidine | 2004 |
A case of life-saving pharmacologic and mechanical coronary dethrombosis.
Topics: Angioplasty, Balloon; Aspirin; Combined Modality Therapy; Coronary Angiography; Coronary Thrombosis; Electrocardiography; Eptifibatide; Fibrinolytic Agents; Heparin; Humans; Intra-Aortic Balloon Pumping; Male; Middle Aged; Myocardial Infarction; Peptides; Platelet Aggregation Inhibitors; Thrombectomy; Ticlopidine; Tissue Plasminogen Activator | 2004 |
Predictors of mortality in patients with acute myocardial infarction and cardiogenic shock.
Topics: Angioplasty, Balloon; Aspirin; C-Reactive Protein; Cholesterol; Electrocardiography; Hormones; Humans; Myocardial Infarction; Odds Ratio; Platelet Aggregation Inhibitors; Predictive Value of Tests; Retrospective Studies; Shock, Cardiogenic; Ticlopidine; Treatment Outcome | 2005 |
[Antithrombotic therapy and dental surgery with bleeding].
Topics: Aspirin; Clopidogrel; Fibrinolytic Agents; Humans; Oral Hemorrhage; Oral Surgical Procedures; Platelet Aggregation Inhibitors; Risk Assessment; Ticlopidine | 2004 |
[Two approaches to correction of disturbed hemostasis in patients with mechanical artificial heart valves at the long-term follow-up].
Topics: Aspirin; Blood Coagulation; Clopidogrel; Drug Therapy, Combination; Female; Fibrinolytic Agents; Follow-Up Studies; Heart Valve Prosthesis; Humans; Male; Nadroparin; Platelet Aggregation Inhibitors; Thromboembolism; Ticlopidine; Treatment Outcome | 2004 |
Reducing the risks of gastrointestinal bleeding with antiplatelet therapies.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Humans; Omeprazole; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine | 2005 |
Clopidogrel-aspirin combination for atrial fibrillation: CLAAF is not CLEAR.
Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Clinical Trials, Phase II as Topic; Clopidogrel; Drug Therapy, Combination; Feasibility Studies; Humans; Pilot Projects; Platelet Aggregation Inhibitors; Research Design; Thromboembolism; Ticlopidine; Warfarin | 2005 |
Elective percutaneous coronary intervention using broad-spectrum antiplatelet therapy (eptifibatide, clopidogrel, and aspirin) alone, without scheduled unfractionated heparin or other antithrombin therapy.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Eptifibatide; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Peptides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Retrospective Studies; Stents; Ticlopidine | 2005 |
Predictive value of plasma plasminogen activator inhibitor-1 for coronary restenosis: dependence on stent implantation and antithrombotic medication.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Combined Modality Therapy; Coronary Restenosis; Female; Fibrinolysis; Fibrinolytic Agents; Humans; Male; Middle Aged; Plasminogen Activator Inhibitor 1; Predictive Value of Tests; Pyridines; Retrospective Studies; Stents; Ticlopidine; Tissue Plasminogen Activator | 2005 |
Long-term combination therapy with aspirin and clopidogrel.
Topics: Angina, Unstable; Arteriosclerosis; Aspirin; Clopidogrel; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Humans; Placebos; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Recurrence; Thrombosis; Ticlopidine; Treatment Outcome | 2004 |
Approach to the assessment of platelet function: comparison between optical-based platelet-rich plasma and impedance-based whole blood platelet aggregation methods.
Topics: Adolescent; Adult; Aspirin; Blood Platelets; Child; Clopidogrel; Diagnostic Tests, Routine; Electric Impedance; Humans; Male; Middle Aged; Plasma; Platelet Aggregation; Platelet Aggregation Inhibitors; Sensitivity and Specificity; Ticlopidine; Valproic Acid | 2005 |
Effects of cilostazol on platelet activation in coronary stenting patients who already treated with aspirin and clopidogrel.
Topics: Aspirin; Cilostazol; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Ischemia; P-Selectin; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Stents; Tetrazoles; Thrombosis; Ticlopidine | 2004 |
Creative cost-effectiveness analysis of CAPRIE data- dust in our eyes.
Topics: Aspirin; Brain Ischemia; Clopidogrel; Cost-Benefit Analysis; Drug Costs; Humans; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Quality-Adjusted Life Years; Risk Factors; Stroke; Ticlopidine | 2005 |
Rapid desensitization procedure for patients with aspirin hypersensitivity undergoing coronary stenting.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Coronary Artery Disease; Desensitization, Immunologic; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Hypersensitivity; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2005 |
Summaries for patients. Is it cost-effective to treat high-risk cardiac patients with clopidogrel plus aspirin as opposed to aspirin alone?
Topics: Angina, Unstable; Aspirin; Cardiovascular Diseases; Clopidogrel; Computer Simulation; Cost-Benefit Analysis; Hemorrhage; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk Factors; Stroke; Ticlopidine | 2005 |
A cost-effectiveness analysis of combination antiplatelet therapy for high-risk acute coronary syndromes: clopidogrel plus aspirin versus aspirin alone.
Topics: Angina, Unstable; Aspirin; Cardiovascular Diseases; Clopidogrel; Computer Simulation; Cost-Benefit Analysis; Electrocardiography; Hemorrhage; Humans; Markov Chains; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Quality-Adjusted Life Years; Recurrence; Risk Factors; Sensitivity and Specificity; Stroke; Ticlopidine | 2005 |
Oral antiplatelet therapy.
Topics: Aspirin; Cerebrovascular Disorders; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Dipyridamole; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2005 |
Impact of combined pharmacologic treatment with clopidogrel and a statin on outcomes of patients with non-ST-segment elevation acute coronary syndromes: perspectives from a large multinational registry.
Topics: Adolescent; Adult; Aged; Angina, Unstable; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Hospitalization; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Myocardial Revascularization; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Treatment Outcome | 2005 |
Immune heparin-induced thrombocytopenia can occur in patients receiving clopidogrel and aspirin.
Topics: Adenosine Diphosphate; Adult; Aged; Antibodies, Monoclonal; Anticoagulants; Aspirin; Clopidogrel; Female; Heparin; Humans; Immunoenzyme Techniques; Male; Platelet Activation; Platelet Factor 4; Thrombocytopenia; Thrombolytic Therapy; Ticlopidine | 2005 |
Nitroaspirin plus clopidogrel versus aspirin plus clopidogrel against platelet thromboembolism and intimal thickening in mice.
Topics: Animals; Aspirin; Blood Coagulation Tests; Clopidogrel; Disease Models, Animal; Drug Therapy, Combination; Hemorrhage; Male; Mice; Mice, Inbred Strains; Platelet Aggregation; Platelet Aggregation Inhibitors; Pulmonary Embolism; Survival Rate; Thromboembolism; Ticlopidine; Tunica Intima | 2005 |
Endovascular stent-assisted angioplasty in the management of traumatic internal carotid artery dissections.
Topics: Adult; Angiography; Angioplasty; Anticoagulants; Aspirin; Blood Platelets; Blood Vessel Prosthesis Implantation; Carotid Arteries; Carotid Artery, Internal; Carotid Artery, Internal, Dissection; Clopidogrel; Constriction, Pathologic; Diffusion; Female; Humans; Ischemia; Male; Middle Aged; Perfusion; Prognosis; Stents; Stroke; Ticlopidine; Time Factors; Tomography, X-Ray Computed; Wounds and Injuries | 2005 |
Erythromelalgia as a presenting manifestation in a patient with essential thrombocythemia complicating renovascular hypertension due to unilateral renal artery stenosis.
Topics: Adult; Angiography; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bone Marrow; Clopidogrel; Diagnosis, Differential; Drug Therapy, Combination; Erythromelalgia; Female; Humans; Hypertension, Renovascular; Platelet Aggregation Inhibitors; Renal Artery; Renal Artery Obstruction; Thrombocytosis; Ticlopidine; Treatment Outcome | 2005 |
Dual antiplatelet therapy for coronary stenting: a clear path for a research agenda.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Stenosis; Coronary Thrombosis; Drug Administration Schedule; Drug Therapy, Combination; Eptifibatide; Hemorrhage; Length of Stay; Membrane Proteins; Peptides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Premedication; Purinergic P2 Receptor Antagonists; Randomized Controlled Trials as Topic; Receptors, Purinergic P2Y12; Risk Factors; Stents; Thrombophilia; Ticlopidine | 2005 |
Concurrent antiplatelet and fibrinolytic therapy.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Thrombolytic Therapy; Ticlopidine | 2005 |
The long-term cost-effectiveness of clopidogrel plus aspirin in patients undergoing percutaneous coronary intervention in Sweden.
Topics: Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Computer Simulation; Coronary Disease; Cost-Benefit Analysis; Drug Administration Schedule; Drug Costs; Drug Therapy, Combination; Female; Humans; Logistic Models; Male; Markov Chains; Middle Aged; Models, Economic; Monte Carlo Method; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors | 2005 |
Effect of clopidogrel with and without aspirin on bleeding following transbronchial lung biopsy.
Topics: Animals; Aspirin; Biopsy, Needle; Bronchoscopy; Clopidogrel; Hemorrhage; Lung; Platelet Aggregation Inhibitors; Swine; Ticlopidine | 2005 |
Repetitive profound thrombocytopenia after treatment with tirofiban: a case report.
Topics: Angioplasty, Balloon; Arterial Occlusive Diseases; Aspirin; Clopidogrel; Drug Administration Schedule; Hospitalization; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Glycoprotein GPIIb-IIIa Complex; Stents; Thrombocytopenia; Ticlopidine; Tirofiban; Tyrosine | 2004 |
[Inhibitory effects of aspirin, clopidogrel, and their combination on the progression of atherosclerosis in rabbits].
Topics: Animals; Aorta; Aspirin; Atherosclerosis; C-Reactive Protein; Cell Count; Clopidogrel; Cyclooxygenase Inhibitors; Drug Synergism; Macrophages; Male; Myocytes, Smooth Muscle; Platelet Aggregation Inhibitors; Rabbits; Random Allocation; Ticlopidine | 2005 |
P2Y12 gene H2 haplotype is not associated with increased adenosine diphosphate-induced platelet aggregation after initiation of clopidogrel therapy with a high loading dose.
Topics: Adenosine Diphosphate; Aged; Aspirin; Clopidogrel; Coronary Disease; Female; Genotype; Haplotypes; Humans; Male; Membrane Proteins; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Receptors, Cell Surface; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Ticlopidine | 2005 |
In-hospital patients exposed to clopidogrel before coronary artery bypass graft surgery: a word of caution.
Topics: Aged; Aspirin; Blood Loss, Surgical; Clopidogrel; Coronary Artery Bypass; Female; Heparin; Hospital Mortality; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Referral and Consultation; Stroke; Ticlopidine | 2005 |
Emerging therapies: clopidogrel and aspirin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arteriosclerosis; Aspirin; Clinical Trials as Topic; Clopidogrel; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Prevalence; Research Design; Thrombosis; Ticlopidine; Treatment Outcome | 2005 |
Unstable angina, stroke, myocardial infarction and death in aspirin non-responders. A prospective, randomized trial. The ASCET (ASpirin non-responsiveness and Clopidogrel Endpoint Trial) design.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angina, Unstable; Aspirin; Blood Platelets; Clopidogrel; Coronary Disease; Drug Resistance; Female; Humans; Male; Middle Aged; Myocardial Infarction; Norway; Platelet Aggregation Inhibitors; Prospective Studies; Randomized Controlled Trials as Topic; Research Design; Risk Factors; Stroke; Ticlopidine | 2004 |
Ask the doctors. I had angioplasty and have one stent. My cardiologist says that I don't need to take clopidogrel (Plavix) plus aspirin. He says one or the other is okay. I'm taking clopidogrel, but notice that advertising for the medication suggest coupl
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2005 |
Drug therapy during percutaneous coronary interventions in stable and unstable coronary artery disease: the Italian Drug Evaluation in Angioplasty (IDEA) study.
Topics: Acetylcysteine; Adrenergic beta-Antagonists; Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Utilization Review; Female; Health Care Surveys; Heparin; Humans; Italy; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Practice Guidelines as Topic; Pyridines; Registries; Ticlopidine | 2005 |
Neurological outcome of conservative versus endovascular treatment of patients with asymptomatic high-grade carotid artery stenosis: a propensity score-adjusted analysis.
Topics: Aged; Angioplasty; Aspirin; Carotid Stenosis; Clopidogrel; Disease-Free Survival; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Proportional Hazards Models; Retrospective Studies; Severity of Illness Index; Stents; Stroke; Ticlopidine; Treatment Outcome; Ultrasonography | 2005 |
Bleeding complications associated with combinations of aspirin, thienopyridine derivatives, and warfarin in elderly patients following acute myocardial infarction.
Topics: Age Factors; Aged; Anticoagulants; Aspirin; Case-Control Studies; Clopidogrel; Cohort Studies; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk Assessment; Ticlopidine; Warfarin | 2005 |
A patient with stent thrombosis, clopidogrel-resistance and failure to metabolize clopidogrel to its active metabolite.
Topics: Aged; Aspirin; Biotransformation; Clopidogrel; Drug Monitoring; Drug Resistance; Humans; Male; Platelet Aggregation; Stents; Thrombosis; Ticlopidine | 2005 |
Clopidogrel versus aspirin and esomeprazole to prevent recurrent bleeding.
Topics: Anti-Ulcer Agents; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Proton Pump Inhibitors; Secondary Prevention; Ticlopidine | 2005 |
Clopidogrel versus aspirin and esomeprazole to prevent recurrent bleeding.
Topics: Anti-Ulcer Agents; Aspirin; Clopidogrel; Cost Savings; Drug Therapy, Combination; Fees, Pharmaceutical; Humans; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine | 2005 |
Clopidogrel versus aspirin and esomeprazole to prevent recurrent bleeding.
Topics: Anti-Ulcer Agents; Aspirin; Clopidogrel; Contraindications; Drug Therapy, Combination; Humans; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Proton Pump Inhibitors; Secondary Prevention; Ticlopidine | 2005 |
Effects of clopidogrel and high dose aspirin on survival of skin flaps in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Male; Platelet Aggregation Inhibitors; Postoperative Complications; Rats; Rats, Wistar; Surgical Flaps; Ticlopidine; Tissue Survival | 2005 |
Counting the true cost of antiplatelet therapy for stroke prevention.
Topics: Aged; Aspirin; Aspirin, Dipyridamole Drug Combination; Clopidogrel; Cost-Benefit Analysis; Dipyridamole; Drug Combinations; Female; Gastrointestinal Diseases; Humans; Male; Platelet Aggregation Inhibitors; Secondary Prevention; Stroke; Ticlopidine; United Kingdom | 2005 |
Cost-effectiveness of clopidogrel.
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Cost-Benefit Analysis; Embolism, Cholesterol; Humans; Myocardial Infarction; Ticlopidine | 2004 |
[Antiplatelet agents and regional anaesthesia: experience in 130 patients].
Topics: Aged; Aspirin; Autonomic Nerve Block; Blood Loss, Surgical; Blood Vessel Prosthesis Implantation; Clopidogrel; Endarterectomy, Carotid; Hematoma; Hemorrhage; Humans; Middle Aged; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Prospective Studies; Punctures; Risk; Ticlopidine | 2005 |
Modelling the long term cost effectiveness of clopidogrel for the secondary prevention of occlusive vascular events in the UK.
Topics: Aged; Aspirin; Clopidogrel; Cost-Benefit Analysis; Female; Humans; Male; Markov Chains; Middle Aged; Models, Economic; Platelet Aggregation Inhibitors; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Ticlopidine; United Kingdom; Vascular Diseases | 2005 |
[Aspirin and cardiovascular prevention: last minute information].
Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Female; Humans; Male; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Secondary Prevention; Ticlopidine | 2005 |
Very late thrombosis after implantation of sirolimus eluting stent.
Topics: Adult; Aspirin; Blood Vessel Prosthesis; Catheterization; Clopidogrel; Coronary Angiography; Coronary Restenosis; Coronary Stenosis; Coronary Thrombosis; Drug Implants; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Male; Platelet Aggregation Inhibitors; Prosthesis Failure; Retreatment; Sirolimus; Stents; Ticlopidine; Time Factors | 2005 |
Neurofibromatosis as a cause of multiple coronary aneurysms.
Topics: Adrenergic beta-Antagonists; Aged; Aspirin; Clopidogrel; Coronary Aneurysm; Coronary Angiography; Female; Humans; Neurofibromatoses; Platelet Aggregation Inhibitors; Ticlopidine | 2005 |
Association of a functional polymorphism in the clopidogrel target receptor gene, P2Y12, and the risk for ischemic cerebrovascular events in patients with peripheral artery disease.
Topics: Aged; Alleles; Aspirin; Brain Ischemia; Cerebrovascular Circulation; Clopidogrel; Cohort Studies; Exons; Gene Frequency; Genetic Predisposition to Disease; Genotype; Heterozygote; Humans; Ischemia; Membrane Proteins; Middle Aged; Mutation; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Polymerase Chain Reaction; Polymorphism, Genetic; Prevalence; Proportional Hazards Models; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Stroke; Ticlopidine; Time Factors; Treatment Outcome | 2005 |
Enhanced shear-induced platelet aggregation in patients who experience subacute stent thrombosis: a case-control study.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Case-Control Studies; Clopidogrel; Coronary Disease; Female; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Stents; Thrombosis; Ticlopidine | 2005 |
Resistance to antiplatelet resistance is it justified?
Topics: Aspirin; Blood Platelets; Clopidogrel; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Stents; Thrombosis; Ticlopidine | 2005 |
The (variable) definition of benefit in the case of clopidogrel vs aspirin.
Topics: Aspirin; Clopidogrel; Humans; Myocardial Infarction; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Treatment Outcome; Vascular Diseases | 2005 |
Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction.
Topics: Aspirin; Clopidogrel; Coronary Circulation; Drug Therapy, Combination; Fibrinolytic Agents; Heparin; Myocardial Infarction; Outcome Assessment, Health Care; Platelet Aggregation Inhibitors; Secondary Prevention; Ticlopidine; Vascular Patency | 2005 |
Use of native or platelet count adjusted platelet rich plasma for platelet aggregation measurements.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Drug Monitoring; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Thrombocytosis; Ticlopidine | 2005 |
Enhancing reperfusion therapy for myocardial infarction with dual antiplatelet therapy: Breaking the glass ceiling.
Topics: Aspirin; Clopidogrel; Coronary Circulation; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Streptokinase; Thrombolytic Therapy; Ticlopidine | 2005 |
[Highlights from the American College of Cardiology Annual Scientific Session 2005: March 5-9, 2005, Orlando, Florida].
Topics: Aspirin; Cardiovascular Diseases; Cholesterol, LDL; Clopidogrel; Humans; Hypercholesterolemia; Obesity; Piperidines; Platelet Aggregation Inhibitors; Pyrazoles; Rimonabant; Stroke; Ticlopidine | 2005 |
Lack of antiapoptotic effects of antiplatelet drug, aspirin and clopidogrel, and antioxidant, MCI-186, against focal ischemic brain damage in rats.
Topics: Animals; Antioxidants; Antipyrine; Aspirin; bcl-2-Associated X Protein; Blotting, Western; Brain Edema; Brain Ischemia; Cerebral Infarction; Clopidogrel; Cyclic AMP Response Element-Binding Protein; Disability Evaluation; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Administration Routes; Edaravone; Functional Laterality; Gene Expression Regulation; Hypoxia, Brain; Male; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; PTEN Phosphohydrolase; Rats; Rats, Sprague-Dawley; Ticlopidine; Tumor Suppressor Proteins | 2005 |
Appropriate use of antiplatelets: is prescription in daily practice influenced by the global cardiovascular risk?
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Drug Utilization; Female; Humans; Italy; Male; Middle Aged; Physicians, Family; Platelet Aggregation Inhibitors; Practice Patterns, Physicians'; Primary Prevention; Risk Assessment; Ticlopidine | 2005 |
Comparative effect of antiplatelet therapy in retinal vein occlusion evaluated by the particle-counting method using light scattering.
Topics: Aspirin; Clopidogrel; Epoprostenol; Humans; Light; Particle Size; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Retinal Vein Occlusion; Scattering, Radiation; Ticlopidine | 2005 |
[Strokes associated with cervical artery dissection, and systemic mastocytosis: an unfortuitous association? A report of two cases].
Topics: Aspirin; Brain Infarction; Carotid Artery, Internal, Dissection; Carotid Stenosis; Clopidogrel; Fibrinolytic Agents; Follow-Up Studies; Humans; Magnetic Resonance Angiography; Male; Mastocytosis, Systemic; Middle Aged; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Time Factors; Vertebral Artery Dissection | 2005 |
Combined pharmacologic treatment with clopidogrel and statin for patients with acute coronary syndrome: is there a survival advantage?
Topics: Aspirin; Clopidogrel; Coronary Disease; Drug Combinations; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Platelet Aggregation Inhibitors; Prospective Studies; Randomized Controlled Trials as Topic; Survival Analysis; Ticlopidine | 2005 |
Platelet function profiles in patients with type 2 diabetes and coronary artery disease on combined aspirin and clopidogrel treatment.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Clopidogrel; Coronary Disease; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; P-Selectin; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2005 |
Study for determination of the optimal cessation period of therapy with anti-platelet agents prior to invasive endoscopic procedures.
Topics: Adult; Aspirin; Bleeding Time; Cohort Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Endoscopy, Gastrointestinal; Gastrointestinal Hemorrhage; Hemostasis; Humans; Male; Maximum Tolerated Dose; Platelet Aggregation Inhibitors; Platelet Function Tests; Probability; Reference Values; Risk Assessment; Sensitivity and Specificity; Statistics, Nonparametric; Ticlopidine; Time Factors | 2005 |
Inflammatory response after intervention assessed by serial C-reactive protein measurements correlates with restenosis in patients treated with coronary stenting.
Topics: Abciximab; Aged; Angina Pectoris; Angina, Unstable; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Aspirin; Biomarkers; C-Reactive Protein; Clopidogrel; Coronary Angiography; Coronary Restenosis; Coronary Stenosis; Female; Heparin; Humans; Immunoglobulin Fab Fragments; Inflammation; Male; Middle Aged; Postoperative Period; Premedication; Stents; Ticlopidine; Tirofiban; Tyrosine | 2005 |
Increased long term rates of stent thrombosis and mortality in patients given clopidogrel as compared to ticlopidine following coronary stent implantation.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Disease; Coronary Thrombosis; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Retrospective Studies; Stents; Ticlopidine | 2005 |
Progressive symptomatic carotid dissection treated with multiple stents.
Topics: Angiography; Angioplasty; Anticoagulants; Aspirin; Blood Vessel Prosthesis Implantation; Carotid Artery, Internal; Carotid Artery, Internal, Dissection; Clopidogrel; Constriction, Pathologic; Follow-Up Studies; Humans; Ischemic Attack, Transient; Magnetic Resonance Imaging; Male; Middle Aged; Platelet Aggregation Inhibitors; Stents; Stroke; Ticlopidine; Time Factors | 2005 |
Clopidogrel reduces migraine with aura after transcatheter closure of persistent foramen ovale and atrial septal defects.
Topics: Adult; Aspirin; Cardiac Catheterization; Clopidogrel; Drug Therapy, Combination; Female; Heart Septal Defects, Atrial; Humans; Male; Medical Audit; Middle Aged; Migraine with Aura; Platelet Aggregation Inhibitors; Postoperative Care; Postoperative Complications; Ticlopidine | 2005 |
[Clopidogrel and upper gastrointestinal hemorrhage].
Topics: Aspirin; Clopidogrel; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Risk Factors; Ticlopidine | 2005 |
[Prophylaxis of stroke].
Topics: Age Factors; Aged; Angioplasty, Balloon; Anticoagulants; Antihypertensive Agents; Aspirin; Atrial Fibrillation; Brain Ischemia; Carotid Stenosis; Clopidogrel; Coronary Disease; Diabetes Mellitus; Diet; Drug Therapy, Combination; Endarterectomy, Carotid; Exercise; Female; Humans; Hypertension; Hypolipidemic Agents; Life Style; Male; Middle Aged; Platelet Aggregation Inhibitors; Primary Prevention; Risk Factors; Sex Factors; Smoking Cessation; Stents; Stroke; Ticlopidine; Time Factors | 2005 |
[Stenting plus coiling: dangerous or helpful?].
Topics: Acute Disease; Aneurysm, Ruptured; Angiography, Digital Subtraction; Aspirin; Calcium Channel Blockers; Cerebral Angiography; Clopidogrel; Embolization, Therapeutic; Follow-Up Studies; Humans; Intracranial Aneurysm; Nimodipine; Platelet Aggregation Inhibitors; Platinum; Risk Factors; Stents; Subarachnoid Hemorrhage; Ticlopidine; Time Factors; Treatment Outcome; Vasodilator Agents | 2005 |
The clinical variability of Wallenberg's syndrome. The anatomical correlate of ipsilateral axial lateropulsion.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Brain; Cerebral Infarction; Clopidogrel; Dipyridamole; Functional Laterality; Gait Disorders, Neurologic; Heparin; Humans; Lateral Medullary Syndrome; Magnetic Resonance Imaging; Male; Medulla Oblongata; Neurologic Examination; Platelet Aggregation Inhibitors; Ticlopidine | 2006 |
Hospitals improve heart attack care. As compliance with guidelines improves, in-hospital deaths fall.
Topics: Aspirin; Cardiac Catheterization; Clopidogrel; Electrocardiography; Guideline Adherence; Hospital Mortality; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine | 2005 |
Secondary stroke prevention with antiplatelet therapy with emphasis on the cardiac patient: a neurologist's view.
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Delayed-Action Preparations; Dipyridamole; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Neurology; Platelet Aggregation Inhibitors; Secondary Prevention; Stroke; Ticlopidine | 2005 |
Ask the doctors. My mother in her early 90s has been diagnosed with atherosclerosis, had a successful angioplasty a year ago for severe chest pain, takes clopidogrel and aspirin, and in general eats a low-fat diet, although she really likes melted ice cre
Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Coronary Artery Disease; Diet, Fat-Restricted; Exercise; Female; Humans; Hypolipidemic Agents; Ice Cream; Platelet Aggregation Inhibitors; Ticlopidine | 2005 |
Adverse reactions to anticoagulants and to antiplatelet drugs recorded by the German spontaneous reporting system.
Topics: Administration, Oral; Adverse Drug Reaction Reporting Systems; Anticoagulants; Aspirin; Association; Blood Cell Count; Cerebral Hemorrhage; Clopidogrel; Databases, Factual; Drug Information Services; Germany; Hemorrhage; Heparin; Humans; Phenprocoumon; Platelet Aggregation Inhibitors; Product Surveillance, Postmarketing; Thrombocytopenia; Ticlopidine; Time Factors; Treatment Outcome; Vitamin K | 2005 |
Flow cytometric measurement of platelet-leukocyte aggregates: a possible target to monitor platelet function?
Topics: Adenosine Diphosphate; Adult; Arterial Occlusive Diseases; Aspirin; Blood Platelets; Clopidogrel; Flow Cytometry; Heart Diseases; Humans; Leukocytes; Male; Monocytes; Peptide Fragments; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Risk; Ticlopidine | 2005 |
Role of the retention test Homburg in evaluating platelet hyperactivity and in monitoring therapy with antiplatelet drugs.
Topics: Abciximab; Adenosine Diphosphate; Antibodies, Monoclonal; Aspirin; Blood Platelets; Cell Shape; Clopidogrel; Collagen; Drug Monitoring; Humans; Immunoglobulin Fab Fragments; P-Selectin; Pilot Projects; Plasma; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Prostaglandins; Ristocetin; Ticlopidine | 2005 |
Investigation of the PADA as a method for monitoring GPIIb/IIIa inhibitors and other antiplatelet agents.
Topics: Abciximab; Adenosine Monophosphate; Antibodies, Monoclonal; Anticoagulants; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Monitoring; Eptifibatide; Hirudins; Humans; Immunoglobulin Fab Fragments; Peptides; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Sensitivity and Specificity; Ticlopidine | 2005 |
Clinical outcomes and left ventricular function in diabetic patients with acute myocardial infarction treated by primary coronary angioplasty.
Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Coronary Artery Bypass; Diabetes Complications; Electrocardiography; Female; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Revascularization; Prognosis; Stroke Volume; Systole; Ticlopidine; Treatment Outcome; Ventricular Function, Left | 2005 |
Oral clopidogrel load in aspirin-resistant capsular warning syndrome.
Topics: Administration, Oral; Aged; Aspirin; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Female; Humans; Internal Capsule; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Stroke; Syndrome; Ticlopidine | 2005 |
The antithrombotic effect of melagatran in combination with clopidogrel and/or aspirin (carotid artery primary thrombosis study).
Topics: Animals; Aspirin; Azetidines; Benzylamines; Bleeding Time; Blood Flow Velocity; Blood Pressure; Carotid Artery Thrombosis; Carotid Artery, Common; Clopidogrel; Disease Models, Animal; Dogs; Drug Therapy, Combination; Female; Fibrinolytic Agents; Heart Rate; Male; Partial Thromboplastin Time; Platelet Aggregation; Platelet Aggregation Inhibitors; Random Allocation; Ticlopidine; Tongue; Vascular Patency | 2005 |
Molecular mechanism of Clopidogrel and Aspirin therapy-induced bleeding episodes.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Eicosanoids; Hemorrhage; Humans; Ticlopidine | 2006 |
Aspirin, but not clopidogrel, reduces collateral conductance in a rabbit model of femoral artery occlusion.
Topics: Animals; Arterial Occlusive Diseases; Aspirin; Clopidogrel; Disease Models, Animal; Electrophysiology; Femoral Artery; Rabbits; Ticlopidine | 2005 |
Cost-effectiveness of clopidogrel plus aspirin versus aspirin alone.
Topics: Angina, Unstable; Aspirin; Cardiovascular Diseases; Clopidogrel; Cost-Benefit Analysis; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2005 |
Cost-effectiveness of clopidogrel plus aspirin versus aspirin alone.
Topics: Angina, Unstable; Aspirin; Cardiovascular Diseases; Clopidogrel; Cost-Benefit Analysis; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2005 |
[Cerebral secondary prevention--clopidogrel alone or in combination with ASS].
Topics: Aged; Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Hemorrhage; Humans; Intracranial Hemorrhages; Ischemic Attack, Transient; Male; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stroke; Ticlopidine; Treatment Outcome | 2005 |
Feasibility trial of carotid stenting with and without an embolus protection device.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Vessel Prosthesis Implantation; Carotid Artery, Common; Carotid Stenosis; Clopidogrel; Feasibility Studies; Female; Graft Occlusion, Vascular; Humans; Intracranial Embolism; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Radiography; Stents; Stroke; Survival Rate; Ticlopidine; Treatment Outcome | 2005 |
Procedure-related complications and early neurological adverse events of unprotected and protected carotid stenting: temporal trends in a consecutive patient series.
Topics: Aged; Aspirin; Blood Vessel Prosthesis Implantation; Carotid Artery, Internal; Carotid Stenosis; Clopidogrel; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Stents; Stroke; Survival Rate; Ticlopidine; Time Factors; Treatment Outcome | 2005 |
Antiplatelet therapy and the vascular tree.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Combined Modality Therapy; Coronary Artery Disease; Drug Resistance; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stroke; Ticlopidine | 2006 |
[ASS or clopidogrel plus esomeprazole after bleeding from an ulcer].
Topics: Aged; Anti-Ulcer Agents; Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Esomeprazole; Female; Humans; Male; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Prospective Studies; Proton Pump Inhibitors; Secondary Prevention; Ticlopidine | 2005 |
Use of evidence-based management for acute coronary syndrome.
Topics: Acute Disease; Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Aspirin; Cardiology; Clopidogrel; Coronary Angiography; Coronary Disease; Evidence-Based Medicine; Female; Guideline Adherence; Heparin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Myocardial Revascularization; New Zealand; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Retrospective Studies; Thrombolytic Therapy; Ticlopidine | 2005 |
ST-elevation myocardial infarction: New Zealand management guidelines.
Topics: Aged; Aspirin; Biomarkers; Cardiology; Clopidogrel; Contraindications; Creatine Kinase; Drug Monitoring; Echocardiography; Electrocardiography; Evidence-Based Medicine; Fibrinolytic Agents; Humans; Myocardial Infarction; Myocardial Revascularization; New Zealand; Platelet Aggregation Inhibitors; Risk Assessment; Thrombolytic Therapy; Ticlopidine; Troponin | 2005 |
Idiopathic spontaneous coronary artery dissection and drug-eluting stents.
Topics: Adult; Aortic Dissection; Aspirin; Clopidogrel; Coronary Aneurysm; Coronary Angiography; Female; Graft Occlusion, Vascular; Humans; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2006 |
Stent thrombosis is associated with an impaired response to antiplatelet therapy.
Topics: Aspirin; Clopidogrel; Humans; Risk Factors; Stents; Thrombosis; Ticlopidine | 2005 |
Does combined clopidogrel and statin therapy benefit patients with non-ST-elevation myocardial infarction?
Topics: Adult; Aged; Aspirin; Clopidogrel; Cohort Studies; Confidence Intervals; Coronary Angiography; Drug Therapy, Combination; Electrocardiography; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Myocardial Infarction; Probability; Prognosis; Registries; Risk Assessment; Severity of Illness Index; Survival Analysis; Ticlopidine; Treatment Outcome | 2005 |
Prior clopidogrel use and outcome of acute coronary syndrome.
Topics: Aspirin; Clopidogrel; Coronary Disease; Humans; Odds Ratio; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2006 |
The cost-effectiveness of dual oral antiplatelet therapy following percutaneous coronary intervention: a Swedish analysis of the CREDO trial.
Topics: Administration, Oral; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Cost-Benefit Analysis; Drug Therapy, Combination; Humans; Markov Chains; Middle Aged; Models, Econometric; Myocardial Infarction; Outcome Assessment, Health Care; Platelet Aggregation Inhibitors; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Stroke; Sweden; Thrombosis; Ticlopidine | 2005 |
Triple versus dual antiplatelet therapy after coronary stenting: impact on stent thrombosis.
Topics: Aspirin; Cilostazol; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Stents; Tetrazoles; Thrombosis; Ticlopidine | 2005 |
Letter regarding article by Markus et al, "Dual antiplatelet therapy with clopidogrel and aspirin in symptomatic cardiac stenosis evaluated using doppler embolic signal detection: the Clopidogrel and Aspirin for Reduction of Emboli in Symptomatic Carotid
Topics: Aspirin; Carotid Stenosis; Clopidogrel; Drug Therapy, Combination; Embolism; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Ultrasonography | 2005 |
Bleeding complications in elderly patients following acute myocardial infarction.
Topics: Aged; Anticoagulants; Aspirin; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk Assessment; Ticlopidine; Warfarin | 2005 |
Platelets treated with ticlopidine are less reactive to unusually large von Willebrand factor multimers than are those treated with aspirin under high shear stress.
Topics: ADAM Proteins; ADAMTS13 Protein; Adult; Age Factors; Aged; Aspirin; Blood Platelets; Brain Ischemia; Female; Humans; Male; Middle Aged; Multiprotein Complexes; Platelet Aggregation Inhibitors; Stress, Mechanical; Ticlopidine; von Willebrand Factor | 2005 |
Since I started taking clopidogrel (Plavix), I've noticed small bruise marks on my body. My doctor says that I should continue taking it. Is that good advice?
Topics: Aspirin; Clopidogrel; Contusions; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2005 |
Letter regarding article by Markus et al, "Dual antiplatelet therapy with clopidogrel and aspirin in symptomatic cardiac stenosis evaluated using doppler embolic signal detection: the Clopidogrel and Aspirin for Reduction of Emboli in Symptomatic Carotid
Topics: Aspirin; Carotid Stenosis; Clopidogrel; Drug Therapy, Combination; Embolism; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Ultrasonography | 2005 |
Aspirin at low-intermediate concentrations protects retinal vessels in experimental diabetic retinopathy through non-platelet-mediated effects.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Blood Platelets; Clopidogrel; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Dinoprostone; Humans; Neurons; Platelet Aggregation Inhibitors; Rats; Retina; Retinal Vessels; Ticlopidine | 2005 |
Life-threatening subcutaneous hemorrhage following minor blunt trauma in an elderly patient taking ticlopidine and aspirin: a case report.
Topics: Abdominal Injuries; Accidental Falls; Aged, 80 and over; Aspirin; Embolization, Therapeutic; Female; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Tomography, X-Ray Computed; Wounds, Nonpenetrating | 2005 |
Aspirin and clopidogrel taken until 2 days prior to coronary artery bypass graft surgery is associated with increased postoperative drainage loss.
Topics: Aged; Aspirin; Blood Transfusion; Clopidogrel; Coronary Artery Bypass; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Reoperation; Ticlopidine | 2005 |
Design of the Dialysis Access Consortium (DAC) Clopidogrel Prevention of Early AV Fistula Thrombosis Trial.
Topics: Arteriovenous Shunt, Surgical; Aspirin; Clopidogrel; Drug Therapy, Combination; Graft Occlusion, Vascular; Humans; Multicenter Studies as Topic; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Renal Dialysis; Research Design; Ticlopidine; Treatment Outcome | 2005 |
Venous thromboembolism and fractured neck of femur.
Topics: Aged; Aged, 80 and over; Anesthesia; Anticoagulants; Aspirin; Blood Loss, Surgical; Blood Transfusion; Clopidogrel; Female; Femoral Neck Fractures; Heparin, Low-Molecular-Weight; Humans; Incidence; Male; Patient Readmission; Platelet Aggregation Inhibitors; Postoperative Complications; Retrospective Studies; Sex Distribution; Ticlopidine; Treatment Outcome; Venous Thrombosis | 2005 |
Treatment disparities in the care of patients with and without diabetes presenting with non-ST-segment elevation acute coronary syndromes.
Topics: Acute Disease; Adrenergic beta-Antagonists; Adult; Aspirin; Cardiac Catheterization; Clopidogrel; Coronary Artery Bypass; Coronary Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Heparin; Humans; Male; Platelet Aggregation Inhibitors; Recurrence; Survival Analysis; Ticlopidine | 2006 |
Influence of aspirin resistance on platelet function profiles in patients on long-term aspirin and clopidogrel after percutaneous coronary intervention.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Collagen Type I; Diabetes Mellitus; Drug Resistance; Drug Therapy, Combination; Epinephrine; Female; Flow Cytometry; Humans; Male; Middle Aged; P-Selectin; Peptide Fragments; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine; Vasoconstrictor Agents | 2006 |
Prevention of carotid artery restenosis after sirolimus-coated stent implantation in pigs.
Topics: Alloys; Angioplasty, Balloon, Coronary; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Atherosclerosis; Carotid Arteries; Clopidogrel; Coronary Angiography; Coronary Restenosis; Disease Models, Animal; Male; Polymers; Sirolimus; Stents; Swine; Ticlopidine; Time Factors; Ultrasonics | 2006 |
Aspirin and clopidogrel drug response in patients undergoing percutaneous coronary intervention: the role of dual drug resistance.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Creatine Kinase, MB Form; Drug Resistance, Multiple; Female; Humans; In Vitro Techniques; Male; Middle Aged; P-Selectin; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Stents; Ticlopidine | 2006 |
Different effects of tirofiban and aspirin plus clopidogrel on myocardial no-reflow in a mini-swine model of acute myocardial infarction and reperfusion.
Topics: Animals; Aspirin; Clopidogrel; Coronary Circulation; Drug Therapy, Combination; Myocardial Infarction; Myocardial Reperfusion; Nitric Oxide; Nitric Oxide Synthase; Platelet Aggregation Inhibitors; Random Allocation; Swine; Swine, Miniature; Ticlopidine; Tirofiban; Tyrosine | 2006 |
Postoperative clopidogrel improves mid-term outcome after off-pump coronary artery bypass graft surgery: a prospective study.
Topics: Aged; Anticoagulants; Aspirin; Chi-Square Distribution; Clopidogrel; Coronary Artery Bypass, Off-Pump; Coronary Disease; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Postoperative Period; Prospective Studies; Recurrence; Regression Analysis; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome | 2006 |
Arterial antithrombotic effects of aspirin, heparin, enoxaparin and clopidogrel alone, or in combination, in the rat.
Topics: Animals; Anticoagulants; Aspirin; Bleeding Time; Carotid Arteries; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enoxaparin; Heparin; Male; Models, Animal; Rats; Rats, Sprague-Dawley; Thrombosis; Ticlopidine | 2006 |
Clopidogrel-aspirin inhibit the thrombogenicity of St. Jude mechanical aortic prostheses.
Topics: Aspirin; Clopidogrel; Heart Valve Diseases; Heart Valve Prosthesis Implantation; Humans; Patient Selection; Platelet Aggregation Inhibitors; Postoperative Complications; Thromboembolism; Ticlopidine | 2006 |
Subarachnoid hemorrhage after lumbar puncture in a patient receiving aspirin and clopidrogel.
Topics: Anticoagulants; Aspirin; Clopidogrel; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Spinal Puncture; Subarachnoid Hemorrhage; Ticlopidine | 2006 |
Upper gastrointestinal mucosal abnormalities and blood loss complicating low-dose aspirin and antithrombotic therapy.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Clopidogrel; Dipyridamole; Drug Administration Schedule; Drug Therapy, Combination; Duodenal Ulcer; Endoscopy, Gastrointestinal; Esophagitis; Female; Fibrinolytic Agents; Gastrointestinal Hemorrhage; Hematemesis; Humans; Intestinal Mucosa; Male; Middle Aged; Platelet Aggregation Inhibitors; Stomach Ulcer; Ticlopidine; Warfarin | 2006 |
[Inhibition of platelet aggregation for the secondary prevention after ACS: when clopidogrel instead of ASA, when clopidogrel and ASA?].
Topics: Acute Disease; Aspirin; Clopidogrel; Coronary Disease; Humans; Platelet Aggregation Inhibitors; Syndrome; Ticlopidine | 2006 |
Efficacy of dual antiplatelet therapy in cerebrovascular disease as demonstrated by a decline in microembolic signals. A report of eight cases.
Topics: Aged; Aspirin; Cerebrovascular Disorders; China; Clopidogrel; Drug Therapy, Combination; Embolism; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Ultrasonography, Doppler, Transcranial | 2006 |
Antiplatelet therapy in stroke prevention: present and future.
Topics: Aspirin; Blood Platelets; Clopidogrel; Dipyridamole; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stroke; Ticlopidine | 2006 |
New modalities and aspects of antiplatelet therapy for stroke prevention.
Topics: Aspirin; Blood Platelets; Cilostazol; Clopidogrel; Drug Design; Drug Resistance; Drug Therapy, Combination; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stroke; Tetrazoles; Ticlopidine | 2006 |
Antiplatelet therapy after percutaneous coronary intervention.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Clopidogrel; Coronary Thrombosis; Drug Resistance; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stents; Tetrazoles; Ticlopidine; Time Factors | 2006 |
[Recommendations for peri-procedural thrombocyte aggregation inhibition].
Topics: Anticoagulants; Aspirin; Clopidogrel; Drug Therapy, Combination; Fibrinolytic Agents; Hemorrhage; Heparin; Humans; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Risk Factors; Surgical Procedures, Operative; Thrombosis; Ticlopidine; Time Factors | 2006 |
Potent low dose platelet inhibitory effects of clopidogrel and aspirin on coronary thrombus formation in an animal model of acute unstable angina.
Topics: Acute Disease; Angina, Unstable; Animals; Aspirin; Clopidogrel; Coronary Thrombosis; Disease Models, Animal; Drug Therapy, Combination; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Swine; Ticlopidine | 2006 |
Clopidogrel withdrawal is associated with proinflammatory and prothrombotic effects in patients with diabetes and coronary artery disease.
Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Diabetes Complications; Diabetes Mellitus; Female; Humans; Inflammation; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Substance Withdrawal Syndrome; Thrombosis; Ticlopidine | 2006 |
The use of embolic signal detection in multicenter trials to evaluate antiplatelet efficacy: signal analysis and quality control mechanisms in the CARESS (Clopidogrel and Aspirin for Reduction of Emboli in Symptomatic carotid Stenosis) trial.
Topics: Aspirin; Carotid Stenosis; Clopidogrel; Humans; Intracranial Embolism; Multicenter Studies as Topic; Platelet Aggregation Inhibitors; Quality Control; Randomized Controlled Trials as Topic; Ticlopidine; Ultrasonography, Doppler, Transcranial | 2006 |
Successful lysis of coronary thrombi by long term warfarin treatment after a failed course of tirofiban infusion.
Topics: Angina Pectoris; Anticoagulants; Aspirin; Clopidogrel; Coronary Thrombosis; Drug Therapy, Combination; Enoxaparin; Female; Humans; Infusion Pumps; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine; Tirofiban; Treatment Failure; Treatment Outcome; Tyrosine; Warfarin | 2006 |
Comparison of ticlopidine vs. clopidogrel in addition to aspirin after paclitaxel-eluting stent implantation: insights from the TRUE (Taxusin Real-life Usage Evaluation) Study.
Topics: Aspirin; Clopidogrel; Coronary Disease; Coronary Restenosis; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Paclitaxel; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Treatment Outcome | 2006 |
[The effect of paclitaxel-eluting stents on restenosis].
Topics: Animals; Aspirin; Clopidogrel; Coronary Angiography; Coronary Disease; Coronary Restenosis; Coronary Vessels; Disease Models, Animal; Humans; Paclitaxel; Platelet Aggregation Inhibitors; Random Allocation; Secondary Prevention; Stents; Swine; Ticlopidine; Tunica Intima; Ultrasonography, Interventional | 2006 |
The risks and safety of clopidogrel in pediatric arterial ischemic stroke.
Topics: Adolescent; Aspirin; Brain Ischemia; Child; Child, Preschool; Clopidogrel; Cohort Studies; Drug Therapy, Combination; Hand; Headache; Hematoma, Subdural; Humans; Hypesthesia; Infant; Infant, Newborn; Moyamoya Disease; Platelet Aggregation Inhibitors; Prospective Studies; Stroke; Ticlopidine; Tomography, X-Ray Computed | 2006 |
Clopidogrel and metoprolol in myocardial infarction.
Topics: Adrenergic beta-Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Humans; Metoprolol; Myocardial Infarction; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Severity of Illness Index; Ticlopidine | 2006 |
Clopidogrel and metoprolol in myocardial infarction.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Gastrointestinal Hemorrhage; Humans; Metoprolol; Myocardial Infarction; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine | 2006 |
Embedded guideline information without patient specificity in a commercial emergency department computerized order-entry system.
Topics: Adrenergic beta-Antagonists; Angina, Unstable; Aspirin; Clopidogrel; Decision Support Systems, Clinical; Emergency Service, Hospital; Fibrinolytic Agents; Guideline Adherence; Heparin; Humans; Medical Order Entry Systems; Myocardial Infarction; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Retrospective Studies; Risk Adjustment; Ticlopidine | 2006 |
The charisma of subgroups and the subgroups of CHARISMA.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Confidence Intervals; Data Interpretation, Statistical; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine | 2006 |
Safety of coronary sirolimus-eluting stents in daily clinical practice: one-year follow-up of the e-Cypher registry.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Cause of Death; Clopidogrel; Comorbidity; Coronary Disease; Coronary Restenosis; Coronary Stenosis; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Drug Implants; Female; Fibrinolytic Agents; Follow-Up Studies; Humans; Internet; Male; Middle Aged; Myocardial Infarction; Product Surveillance, Postmarketing; Registries; Risk Factors; Sirolimus; Stents; Thrombosis; Ticlopidine; United States | 2006 |
Variability in responsiveness to clopidogrel in patients with intermittent claudication.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Humans; Intermittent Claudication; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine | 2006 |
Nickel release, a possible indicator for the duration of antiplatelet treatment, from a nickel cardiac device in vivo: a study in patients with atrial septal defects implanted with an Amplatzer occluder.
Topics: Adult; Aged; Alloys; Aspirin; Clopidogrel; Female; Heart Septal Defects, Atrial; Humans; Male; Middle Aged; Nickel; Platelet Aggregation Inhibitors; Prostheses and Implants; Ticlopidine | 2006 |
High prevalence of previous antiplatelet drug use in patients with new or recurrent ischemic stroke: Buffalo metropolitan area and Erie County stroke study.
Topics: Aspirin; Brain Ischemia; Clopidogrel; Cross-Sectional Studies; Drug Therapy, Combination; Hospitalization; Humans; New York; Platelet Aggregation Inhibitors; Prevalence; Retrospective Studies; Risk Assessment; Risk Factors; Secondary Prevention; Stroke; Ticlopidine; Treatment Outcome | 2006 |
Increased use of selective serotonin reuptake inhibitors in patients admitted with gastrointestinal haemorrhage: a multicentre retrospective analysis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Black or African American; Blood Coagulation; Case-Control Studies; Clopidogrel; Drug Interactions; Enoxaparin; Female; Gastrointestinal Hemorrhage; Hispanic or Latino; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Selective Serotonin Reuptake Inhibitors; Ticlopidine; Warfarin; White People | 2006 |
Combined aspirin and clopidogrel resistance associated with recurrent coronary stent thrombosis.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Combined Modality Therapy; Coronary Restenosis; Coronary Stenosis; Coronary Thrombosis; Drug Resistance; Drug Therapy, Combination; Female; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Recurrence; Stents; Ticlopidine; Treatment Failure | 2006 |
[Postoperative antithrombotic treatment in diabetic patients].
Topics: Anticoagulants; Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Diabetes Mellitus; Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Postoperative Complications; Risk Factors; Thrombosis; Ticlopidine; Warfarin | 2006 |
Differential antiplatelet effects of angiotensin converting enzyme inhibitors: comparison of ex vivo platelet aggregation in cardiovascular patients with ramipril, captopril and enalapril.
Topics: Adenosine Diphosphate; Aged; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Captopril; Cardiovascular Diseases; Clopidogrel; Collagen; Coronary Artery Disease; Electric Impedance; Enalapril; Female; Fibrinolytic Agents; Germany; Humans; Hypertension; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Ramipril; Ticlopidine; Treatment Outcome | 2006 |
Images in cardiology. Unexpected response of saphenous vein graft occlusion to antiplatelet drugs.
Topics: Aged; Aspirin; Clopidogrel; Graft Occlusion, Vascular; Humans; Male; Platelet Aggregation Inhibitors; Saphenous Vein; Ticlopidine | 2006 |
[Emergency measures in acute arterial occlusion. Why there are still colleagues who do it incorrectly?].
Topics: Acute Disease; Angiography; Arterial Occlusive Diseases; Aspirin; Clopidogrel; Embolism; Emergencies; Heparin; Humans; Injections, Intravenous; Leg; Male; Platelet Aggregation Inhibitors; Thromboangiitis Obliterans; Ticlopidine; Ulnar Artery | 2006 |
Contribution of gene sequence variations of the hepatic cytochrome P450 3A4 enzyme to variability in individual responsiveness to clopidogrel.
Topics: Adenine; Alleles; Anticoagulants; Aspirin; Blood Platelets; Clopidogrel; Cohort Studies; Coronary Artery Disease; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Genetic Variation; Genotype; Guanine; Humans; Introns; Liver; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Polymorphism, Genetic; Ticlopidine | 2006 |
[More modest use in secondary prevention, risky in primary prevention].
Topics: Arteriosclerosis; Aspirin; Cause of Death; Clopidogrel; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Follow-Up Studies; Humans; Intracranial Embolism; Myocardial Infarction; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Secondary Prevention; Survival Rate; Ticlopidine | 2006 |
[Thrombosis of a coronary stent after discontinuing treatment with clopidogrel].
Topics: Adult; Aged; Angina Pectoris; Aspirin; Clopidogrel; Female; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine | 2006 |
Growth in clopidogrel-aspirin combination therapy.
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Data Collection; Drug Therapy, Combination; Drug Utilization; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; United States | 2006 |
Catheter thrombosis during primary percutaneous coronary intervention for acute ST elevation myocardial infarction despite subcutaneous low-molecular-weight heparin, acetylsalicylic acid, clopidogrel and abciximab pretreatment.
Topics: Abciximab; Adult; Aged; Angioplasty, Balloon, Coronary; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Anticoagulants; Aspirin; Cardiac Catheterization; Clopidogrel; Enoxaparin; Female; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombolytic Therapy; Thrombosis; Ticlopidine | 2006 |
Comment: mortality benefit of no-load clopidogrel in COMMIT: not a surprise.
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine | 2006 |
[Even in 60-year-old atrial fibrillation is not uncommon. Advances in long-term treatment].
Topics: Administration, Oral; Age Factors; Anti-Arrhythmia Agents; Anticoagulants; Aspirin; Atrial Fibrillation; Catheter Ablation; Clopidogrel; Drug Therapy, Combination; Fibrinolytic Agents; Germany; Humans; Middle Aged; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Registries; Risk Factors; Thromboembolism; Ticlopidine; Vitamin K | 2006 |
Antithrombotic therapy in heart failure.
Topics: Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Aspirin; Clopidogrel; Drug Interactions; Heart Failure; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Thromboembolism; Ticlopidine; Warfarin | 2006 |
Late in-stent thrombosis following carotid angioplasty and stenting.
Topics: Aged; Aged, 80 and over; Angiography, Digital Subtraction; Angioplasty, Balloon; Anticoagulants; Aphasia; Aspirin; Basal Ganglia; Calcinosis; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Carotid Artery, Internal; Carotid Stenosis; Clopidogrel; Hematuria; Heparin; Humans; Infarction, Middle Cerebral Artery; Male; Mouth Neoplasms; Neck Dissection; Neoplasm Recurrence, Local; Paresis; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine; Time Factors; Ultrasonography; Urinary Bladder Neoplasms; Vertigo | 2006 |
[Drug-releasing stents. Little use in cardiology despite excellent data--what next?].
Topics: Aspirin; Clopidogrel; Delayed-Action Preparations; Humans; Platelet Aggregation Inhibitors; Risk Factors; Stents; Thrombosis; Ticlopidine | 2006 |
Lupus anticoagulant and ischemic myocardial microangiopathy in rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Aspirin; Clopidogrel; Echocardiography; Humans; Interleukin 1 Receptor Antagonist Protein; Lupus Coagulation Inhibitor; Male; Methotrexate; Middle Aged; Myocardial Ischemia; Platelet Aggregation Inhibitors; Prednisolone; Radionuclide Imaging; Sialoglycoproteins; Ticlopidine | 2006 |
Combination therapy with aspirin, clopidogrel and warfarin following coronary stenting is associated with a significant risk of bleeding.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Hemorrhage; Humans; Incidence; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Assessment; Severity of Illness Index; Stents; Ticlopidine; Warfarin | 2006 |
Aspirin and clopidogrel resistance: an emerging clinical entity.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2006 |
[Clopidogrel and aspirin versus aspirin alone in prevention of atherothrombotic events. The results of CHARISMA study].
Topics: Aged; Arteriosclerosis; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Severity of Illness Index; Thrombosis; Ticlopidine; Treatment Outcome | 2006 |
A case of fatal stent thrombosis after Carbostent implantation: is clopidogrel alone antiplatelet therapy a safe alternative to aspirin alone antiplatelet therapy?
Topics: Aged; Aspirin; Clopidogrel; Fatal Outcome; Humans; Male; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine | 2007 |
Late in-stent thrombosis in a patient with systemic lupus erythematosus and hyperhomocysteinemia while on clopidogrel and aspirin.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Blood Coagulation Disorders; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Female; Humans; Hyperhomocysteinemia; Lupus Erythematosus, Systemic; Middle Aged; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Time Factors | 2006 |
Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1- and cyclooxygenase-2-independent pathway: a 700-patient study of aspirin resistance.
Topics: Adenosine Diphosphate; Arachidonic Acid; Aspirin; Clopidogrel; Coronary Artery Disease; Cyclooxygenase 1; Cyclooxygenase 2; Dose-Response Relationship, Drug; Drug Resistance; Female; Flow Cytometry; Humans; Male; Middle Aged; Multivariate Analysis; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Recurrence; Signal Transduction; Thrombosis; Thromboxane B2; Ticlopidine; Time Factors; Treatment Refusal | 2006 |
Plavix isn't for everyone. Adding Plavix to aspirin doesn't help people without heart disease.
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine | 2006 |
Use of whole blood platelet lumi-aggregometry to optimize anti-platelet therapy in patients with chronic myeloproliferative disorders.
Topics: Aspirin; Chronic Disease; Clopidogrel; Dietary Supplements; Dose-Response Relationship, Drug; Garlic; Humans; Luminescent Measurements; Myeloproliferative Disorders; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2006 |
Antiplatelet therapy prior to carotid endarterectomy--still room for improvement.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Austria; Carotid Artery, Internal; Carotid Stenosis; Clopidogrel; Drug Utilization; Endarterectomy, Carotid; Female; Guideline Adherence; Health Care Surveys; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Practice Patterns, Physicians'; Premedication; Stroke; Ticlopidine | 2006 |
Reversible ageusia associated with clopidogrel treatment.
Topics: Ageusia; Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine | 2006 |
Enhanced platelet activation by prolactin in patients with ischemic stroke.
Topics: Aged; Aged, 80 and over; Aspirin; Brain Ischemia; Clopidogrel; Female; Humans; Ischemic Attack, Transient; Leptin; Male; Middle Aged; P-Selectin; Platelet Activation; Prolactin; Retrospective Studies; Risk Factors; Stroke; Thrombophilia; Ticlopidine | 2006 |
Sub-Tenon's anesthesia with aspirin, warfarin, and clopidogrel.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anticoagulants; Aspirin; Cardiovascular Diseases; Cerebrovascular Disorders; Clopidogrel; Conjunctival Diseases; Connective Tissue; Eye Hemorrhage; Female; Humans; Lens Implantation, Intraocular; Male; Medical Audit; Middle Aged; Phacoemulsification; Prospective Studies; Risk Factors; Ticlopidine; Warfarin | 2006 |
Use of ticlopidine and cilostazol after intracoronary drug-eluting stent placement in a patient with previous clopidogrel-induced thrombotic thrombocytopenic purpura: a case report.
Topics: ADAM Proteins; ADAMTS1 Protein; Aged; Apoptosis; Aspirin; Autoantibodies; Cilostazol; Clopidogrel; Coronary Artery Bypass; Coronary Disease; Coronary Thrombosis; Drug Therapy, Combination; Endothelium, Vascular; Female; Humans; Plasmapheresis; Platelet Aggregation Inhibitors; Purpura, Thrombotic Thrombocytopenic; Stents; Tetrazoles; Ticlopidine | 2006 |
An alternative treatment strategy for pump thrombus in the DeBakey VAD Child: use of clopidogrel as a thrombolytic agent.
Topics: Adolescent; Aspirin; Cardiomyopathy, Dilated; Clopidogrel; Equipment Failure; Fibrinolytic Agents; Heart Transplantation; Heart-Assist Devices; Humans; Male; Thrombosis; Ticlopidine; Warfarin | 2006 |
Carotid stenting.
Topics: Aged; Aspirin; Cardiovascular Agents; Carotid Artery, Internal; Carotid Stenosis; Clopidogrel; Endarterectomy, Carotid; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Platelet Aggregation Inhibitors; Stents; Stroke; Ticlopidine | 2006 |
Medical management of peripheral arterial disease.
Topics: Aspirin; Clopidogrel; Cost-Benefit Analysis; Humans; Peripheral Vascular Diseases; Phthalic Acids; Platelet Aggregation Inhibitors; Ticlopidine | 2006 |
Spontaneous abdominal hematoma in a patient treated with clopidogrel and aspirin.
Topics: Abdominal Cavity; Abdominal Pain; Aged; Aspirin; Clopidogrel; Hematoma; Humans; Kidney Diseases; Male; Platelet Aggregation Inhibitors; Ticlopidine | 2006 |
[Gastroenterology in family practice. Updates for your "stomach patient"].
Topics: Anti-Ulcer Agents; Aspirin; Clopidogrel; Dyspepsia; Esophagitis, Peptic; Family Practice; Heartburn; Helicobacter Infections; Humans; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Recurrence; Ticlopidine | 2006 |
[Bilateral hemothorax secondary to combined antiplatelet therapy with clopidogrel and acetylsalicylic acid].
Topics: Aged; Aspirin; Clopidogrel; Drug Therapy, Combination; Hemothorax; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine | 2006 |
Aspirin and clopidogrel resistance.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Resistance, Multiple; Humans; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine | 2006 |
Unveiling the inflammatory face of antiplatelet drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Disease; Humans; Inflammation; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; Up-Regulation | 2006 |
More on: enhanced antiplatelet effect of clopidogrel in patients whose platelets are least inhibited by aspirin: a randomized cross-over trial.
Topics: Aspirin; Blood Platelets; Clopidogrel; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine | 2006 |
Insulin therapy is associated with platelet dysfunction in patients with type 2 diabetes mellitus on dual oral antiplatelet treatment.
Topics: Aged; Aspirin; Clopidogrel; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Drug Therapy, Combination; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2006 |
[Combination of clopidogrel and aspirin was no better than aspirin alone for prevention of atherothrombotic events in stable patients. Results of CHARISMA].
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Severity of Illness Index; Ticlopidine; Treatment Outcome | 2006 |
Documented subacute stent thrombosis within thirty days after stenting with sirolimus-eluting stent (Cypher) for acute myocardial infarction: a Japanese single center retrospective non-randomized study.
Topics: Aged; Aspirin; Coronary Restenosis; Coronary Thrombosis; Disease Progression; Female; Humans; Immunosuppressive Agents; Incidence; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Retrospective Studies; Sirolimus; Stents; Ticlopidine; Time Factors | 2006 |
Clopidogrel for the prevention of atherothrombotic events.
Topics: Aspirin; Cerebral Hemorrhage; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2006 |
Clopidogrel for the prevention of atherothrombotic events.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Data Interpretation, Statistical; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Research Design; Ticlopidine | 2006 |
Clopidogrel for the prevention of atherothrombotic events.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2006 |
Clopidogrel for the prevention of atherothrombotic events.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Incidence; Platelet Aggregation Inhibitors; Ticlopidine | 2006 |
Clopidogrel for the prevention of atherothrombotic events.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2006 |
Long-term clinical outcome of patients treated with beta-brachytherapy in routine clinical practice.
Topics: Aspirin; Brachytherapy; Clopidogrel; Coronary Restenosis; Coronary Stenosis; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Stents; Ticlopidine; Time Factors; Treatment Outcome | 2007 |
Influence of omeprazol on the antiplatelet action of clopidogrel associated to aspirin.
Topics: Aged; Angioplasty; Aryl Hydrocarbon Hydroxylases; Aspirin; Cell Adhesion Molecules; Clopidogrel; Coronary Disease; Cytochrome P-450 CYP2C19; Drug Antagonism; Enzyme Inhibitors; Female; Humans; Male; Microfilament Proteins; Mixed Function Oxygenases; Omeprazole; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Single Nucleotide; Protein Processing, Post-Translational; Thrombosis; Ticlopidine | 2006 |
Viscosity, hemostasis and inflammation in atherosclerotic heart diseases.
Topics: Aged; Aspirin; Blood Viscosity; Brain Ischemia; Clopidogrel; Coronary Artery Disease; Diabetes Complications; Female; Glucose; Glycated Hemoglobin; Hemostasis; Humans; Inflammation; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; von Willebrand Factor | 2006 |
Cyclooxygenase-2 inhibitors enhance shear stress-induced platelet aggregation.
Topics: Animals; Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Stenosis; Cyclooxygenase Inhibitors; Isoxazoles; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Risk Factors; Shear Strength; Thrombosis; Ticlopidine | 2006 |
The significance of incomplete stent apposition in patients undergoing stenting of internal carotid artery stenosis.
Topics: Aged; Aged, 80 and over; Angioplasty, Balloon; Aspirin; Brain Ischemia; Carotid Arteries; Carotid Stenosis; Female; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Platelet Aggregation Inhibitors; Prognosis; Radiography, Interventional; Recurrence; Retrospective Studies; Stents; Ticlopidine | 2006 |
Aspirin still best for clot prevention.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2006 |
Iliac anastomotic stenting with a biodegradable poly-L-lactide stent: a preliminary study after 1 and 6 weeks.
Topics: Absorbable Implants; Anastomosis, Surgical; Animals; Arteritis; Aspirin; Clopidogrel; Feasibility Studies; Female; Iliac Artery; Laser-Doppler Flowmetry; Pilot Projects; Platelet Aggregation Inhibitors; Polyesters; Stents; Swine; Thrombosis; Ticlopidine; Tunica Intima; Ultrasonography | 2006 |
Impact of PlA polymorphism of platelet GP IIb/IIIa receptors on clinical course during long-term LVAD support is independent of type of LVAD.
Topics: Anticoagulants; Antigens, Human Platelet; Aspirin; Clopidogrel; Equipment Design; Genetic Predisposition to Disease; Genotype; Heart-Assist Devices; Hemorrhagic Disorders; Humans; Incidence; Integrin beta3; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Polymorphism, Genetic; Postoperative Complications; Thromboembolism; Thrombophilia; Ticlopidine | 2006 |
Response to aspirin and clopidogrel monitored with different platelet function methods.
Topics: Aged; Arterial Occlusive Diseases; Aspirin; Automation; Blood Platelets; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2006 |
Surgical revascularisation in patients with severe limb ischaemia induces a pro-thrombotic state.
Topics: Aged; Aged, 80 and over; Antithrombin III; Arterial Occlusive Diseases; Aspirin; Blood Coagulation; Clopidogrel; Female; Fibrin Fibrinogen Degradation Products; Humans; Ischemia; Male; P-Selectin; Peptide Hydrolases; Platelet Aggregation; Platelet Aggregation Inhibitors; Postoperative Complications; Reperfusion; Thrombosis; Ticlopidine; Vascular Surgical Procedures; von Willebrand Factor | 2006 |
[Physicians and insurance may collaborate on therapy].
Topics: Aspirin; Clopidogrel; Contract Services; Cooperative Behavior; Cost-Benefit Analysis; Drug Costs; Family Practice; Germany; Humans; Interprofessional Relations; Myocardial Infarction; National Health Programs; Physician's Role; Stroke; Ticlopidine | 2006 |
Antiplatelet agents aspirin and clopidogrel are hydrolyzed by distinct carboxylesterases, and clopidogrel is transesterificated in the presence of ethyl alcohol.
Topics: Animals; Aspirin; Carboxylic Ester Hydrolases; Cell Line, Tumor; Cell Survival; Central Nervous System Depressants; Chromatography, High Pressure Liquid; Clopidogrel; Esters; Ethanol; Humans; Hydrolysis; In Vitro Techniques; Intestinal Mucosa; Microsomes; Microsomes, Liver; Mutagenesis, Site-Directed; Platelet Aggregation Inhibitors; Rats; Ticlopidine; Transfection | 2006 |
[When ASS, when anticoagulants?].
Topics: Administration, Oral; Age Factors; Aged; Anticoagulants; Aspirin; Clopidogrel; Female; Heart Diseases; Heparin, Low-Molecular-Weight; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Primary Prevention; Risk Factors; Sex Factors; Stroke; Ticlopidine; Time Factors | 2006 |
[Cost-effectiveness of clopidogrel vs. aspirin treatment in high-risk acute coronary syndrome patients in Denmark].
Topics: Acute Disease; Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Bypass; Coronary Disease; Cost-Benefit Analysis; Humans; Ischemia; Leg; Middle Aged; Myocardial Ischemia; Platelet Aggregation Inhibitors; Risk Factors; Stroke; Syndrome; Ticlopidine | 2006 |
Plasma levels of the growth arrest-specific gene 6 product (Gas6) and antiplatelet drug responsiveness in healthy subjects.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Drug Resistance; Enzyme-Linked Immunosorbent Assay; Humans; Intercellular Signaling Peptides and Proteins; Mice; Odds Ratio; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Regression Analysis; Risk; Ticlopidine | 2006 |
[Prevention of vascular events after transient ischemic attack or cerebral infarct].
Topics: Angioplasty, Balloon; Anticoagulants; Aspirin; Cerebral Infarction; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; Hypolipidemic Agents; Ischemic Attack, Transient; Phosphodiesterase Inhibitors; Platelet Aggregation Inhibitors; Recurrence; Risk Factors; Stents; Stroke; Ticlopidine; Time Factors; Warfarin | 2006 |
Platelet function in patients with acute coronary syndrome (ACS) predicts recurrent ACS.
Topics: Acute Disease; Adrenergic beta-Antagonists; Aspirin; Clopidogrel; Coronary Disease; Diabetes Complications; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Odds Ratio; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Recurrence; Research Design; Risk Assessment; Stress, Mechanical; Syndrome; Ticlopidine; Time Factors; von Willebrand Factor | 2006 |
Biosignatures in thrombotic disorders.
Topics: Aspirin; Biomarkers; Clopidogrel; Drug Therapy, Combination; Gene Expression Profiling; Humans; Patient Selection; Platelet Aggregation Inhibitors; Predictive Value of Tests; Risk Factors; Thrombosis; Ticlopidine | 2006 |
Antiplatelet and anticoagulant therapy in patients with giant cell arteritis.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Brain Ischemia; Clopidogrel; Cohort Studies; Dose-Response Relationship, Drug; Female; Giant Cell Arteritis; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Stroke; Ticlopidine; Warfarin | 2006 |
Aspirin and clopidogrel resistance in patients with diabetes mellitus.
Topics: Aspirin; Clopidogrel; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine | 2006 |
[Bleeding complications after treatment with antithrombotic agents after acute coronary syndrome].
Topics: Acute Disease; Aspirin; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Fibrinolytic Agents; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Thrombolytic Therapy; Ticlopidine | 2006 |
[Bleeding complications after treatment with clopidogrel and acetylsalicylic acid after acute coronary syndrome].
Topics: Age Factors; Aged; Angina, Unstable; Aspirin; Clopidogrel; Coronary Artery Bypass; Drug Therapy, Combination; Female; Fibrinolytic Agents; Follow-Up Studies; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk Factors; Stroke; Thrombolytic Therapy; Ticlopidine | 2006 |
[Antiplatelet therapy after aspirin-induced upper gastrointestinal bleeding].
Topics: Anti-Ulcer Agents; Aspirin; Clopidogrel; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combination; Esomeprazole; Evidence-Based Medicine; Fibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Recurrence; Risk Factors; Ticlopidine | 2006 |
Late thrombosis of drug-eluting stents after discontinuation of clopidogrel: report of two cases and review of the literature.
Topics: Aged, 80 and over; Aspirin; Clopidogrel; Coronary Thrombosis; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Radiography; Stents; Thrombosis; Ticlopidine; Time Factors; Ultrasonography | 2006 |
Premature discontinuation of antiplatelet therapy in patients with drug-eluting coronary stents.
Topics: Aspirin; Clopidogrel; Coronary Restenosis; Coronary Vessels; Delayed-Action Preparations; Humans; Paclitaxel; Perioperative Care; Platelet Aggregation Inhibitors; Postoperative Complications; Sirolimus; Stents; Ticlopidine | 2006 |
A cost analysis in patients with acute coronary syndrome using clopidogrel in addition to aspirin in a Hong Kong public hospital.
Topics: Aged; Aspirin; Clopidogrel; Coronary Disease; Costs and Cost Analysis; Female; Hong Kong; Humans; Male; Platelet Aggregation Inhibitors; Retrospective Studies; Syndrome; Ticlopidine | 2006 |
Role of antiplatelets in carotid artery stenting.
Topics: Angioplasty, Balloon; Aspirin; Carotid Stenosis; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Eptifibatide; Humans; Peptides; Platelet Aggregation Inhibitors; Stents; Stroke; Ticlopidine | 2007 |
[The CHARISMA study: in search of the best antiplatelet strategy for cardiovascular prevention].
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Platelet Aggregation Inhibitors; Prospective Studies; Randomized Controlled Trials as Topic; Ticlopidine | 2006 |
A current problem in cardiology: very late thrombosis after implantation of sirolimus eluting stent.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Thrombosis; Drug-Eluting Stents; Humans; Immunosuppressive Agents; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Recurrence; Sirolimus; Ticlopidine; Time Factors | 2007 |
Antithrombotic therapy and predilection for cerebellar hemorrhage.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anticoagulants; Arteriosclerosis; Aspirin; Blood Glucose; Cerebellar Diseases; Female; Fibrinolytic Agents; Heart Diseases; Humans; Intracranial Hemorrhages; Japan; Male; Middle Aged; Odds Ratio; Platelet Aggregation Inhibitors; Predictive Value of Tests; Prospective Studies; Registries; Risk Assessment; Risk Factors; Stroke; Ticlopidine; Time Factors; Warfarin | 2007 |
Effect of clopidogrel plus aspirin on ST segments in patients with ST-elevation acute myocardial infarction.
Topics: Aspirin; Clopidogrel; Electrocardiography; Female; Fibrinolytic Agents; Humans; Length of Stay; Logistic Models; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Stroke Volume; Ticlopidine | 2006 |
Effectiveness of same day percutaneous coronary intervention followed by minimally invasive aortic valve replacement for aortic stenosis and moderate coronary disease ("hybrid approach").
Topics: Aged; Aged, 80 and over; Aortic Valve; Aortic Valve Stenosis; Aspirin; Clopidogrel; Coronary Disease; Elective Surgical Procedures; Female; Humans; Male; Middle Aged; Minimally Invasive Surgical Procedures; Prospective Studies; Stents; Ticlopidine | 2006 |
Clopidogrel response variability and future therapies: clopidogrel: does one size fit all?
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Chest Pain; Clopidogrel; Coronary Angiography; Electrocardiography; Female; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Recurrence; Stents; Ticlopidine; Treatment Outcome | 2006 |
Neointimal coverage of sirolimus-eluting stents at 6-month follow-up: evaluated by optical coherence tomography.
Topics: Aged; Aspirin; Catheterization; Cell Proliferation; Coronary Restenosis; Coronary Thrombosis; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Male; Sirolimus; Stents; Ticlopidine; Tomography, Optical Coherence; Tunica Intima | 2007 |
The platelet inhibiting effect of a clopidogrel bolus dose in patients on long-term acetylsalicylic acid treatment.
Topics: Aged; Aspirin; Blood Coagulation Tests; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fibrinogen; Flow Cytometry; Humans; Male; Middle Aged; P-Selectin; Platelet Aggregation Inhibitors; Protein Binding; Reference Values; Thrombelastography; Ticlopidine; Time Factors | 2007 |
Effect of clopidogrel on the inflammatory progression of early atherosclerosis in rabbits model.
Topics: Animals; Aspirin; Atherosclerosis; Atorvastatin; Chemokine CCL2; Clopidogrel; Diet, Atherogenic; Disease Models, Animal; Femoral Artery; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Intercellular Adhesion Molecule-1; Male; P-Selectin; Platelet Aggregation Inhibitors; Pyrroles; Rabbits; Ticlopidine; Vascular Cell Adhesion Molecule-1 | 2007 |
Stroke: the dashed hopes of neuroprotection.
Topics: Acute Disease; Aspirin; Benzenesulfonates; Carotid Arteries; Clopidogrel; Dipyridamole; Europe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Neuroprotective Agents; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stents; Stroke; Ticlopidine | 2007 |
Anticoagulant and antiplatelet therapy use in patients with atrial fibrillation undergoing percutaneous coronary intervention: the need for consensus and a management guideline.
Topics: Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Cohort Studies; Combined Modality Therapy; Consensus Development Conferences as Topic; Coronary Stenosis; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Heparin, Low-Molecular-Weight; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Risk Factors; Stents; Stroke; Ticlopidine; Warfarin | 2006 |
Clinical trials update from the annual scientific session of the American College of Cardiology 2006.
Topics: Aspirin; Cardiac Catheterization; Cardiology; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Enoxaparin; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Societies, Medical; Stents; Thrombolytic Therapy; Ticlopidine; United States | 2006 |
Effects of applying a standardised management algorithm for moderate to severe renal dysfunction in patients with chronic stable heart failure.
Topics: Aged; Algorithms; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Clopidogrel; Creatinine; Female; Heart Failure; Humans; Kidney Diseases; Magnetic Resonance Angiography; Male; Prognosis; Prospective Studies; Renal Artery Obstruction; Risk Factors; Severity of Illness Index; Sickness Impact Profile; Ticlopidine; Treatment Outcome | 2007 |
Long-term cost-effectiveness of clopidogrel in patients with acute coronary syndrome without ST-segment elevation in Germany.
Topics: Acute Coronary Syndrome; Adult; Age Factors; Aged; Aspirin; Clopidogrel; Cost-Benefit Analysis; Electrocardiography; Female; Germany; Humans; Male; Markov Chains; Middle Aged; Models, Economic; Myocardial Infarction; Platelet Aggregation Inhibitors; Sex Factors; Ticlopidine | 2007 |
[Safety of aspirin, clopidogrel, and acenocumarol combination in patients requiring anticoagulation].
Topics: Acenocoumarol; Aged; Anticoagulants; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine | 2006 |
[Platelet inhibition and gastric problems].
Topics: Anti-Ulcer Agents; Aspirin; Clopidogrel; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Omeprazole; Platelet Aggregation Inhibitors; Ticlopidine | 2007 |
Stent thrombosis: consider also low response to antiplatelets.
Topics: Aspirin; Clopidogrel; Coronary Restenosis; Coronary Thrombosis; Drug Implants; Humans; Platelet Aggregation Inhibitors; Prosthesis Failure; Stents; Ticlopidine | 2007 |
Primary stent therapy for symptomatic intracranial atherosclerotic stenosis: 1-year follow-up angiographic and midterm clinical outcomes.
Topics: Adult; Aged; Aspirin; Cerebral Angiography; Clopidogrel; Female; Follow-Up Studies; Humans; Intracranial Arteriosclerosis; Male; Middle Aged; Neurologic Examination; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2006 |
Prevention of vascular events in atrial fibrillation.
Topics: Accidental Falls; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2007 |
Platelet non-responsiveness to dual antiplatelet therapy and relation to coronary disease among diabetes patients.
Topics: Adult; Aspirin; Blood Platelets; Case-Control Studies; Clopidogrel; Coronary Disease; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Pilot Projects; Reference Values; Risk Assessment; Ticlopidine; Treatment Failure | 2007 |
What is the optimal management for preventing saphenous vein graft diseases?: early results of intravascular angioscopic assessment.
Topics: Aged; Aged, 80 and over; Angioscopy; Anticoagulants; Aspirin; Coronary Artery Bypass; Graft Occlusion, Vascular; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Middle Aged; Platelet Aggregation Inhibitors; Saphenous Vein; Ticlopidine | 2007 |
Late in-stent thrombosis following carotid angioplasty and stenting.
Topics: Aged; Aged, 80 and over; Angiography, Digital Subtraction; Angioplasty, Balloon; Anticoagulants; Aphasia; Aspirin; Basal Ganglia; Calcinosis; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Carotid Artery, Internal; Carotid Stenosis; Clopidogrel; Hematuria; Heparin; Humans; Infarction, Middle Cerebral Artery; Male; Mouth Neoplasms; Neck Dissection; Neoplasm Recurrence, Local; Paresis; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine; Time Factors; Ultrasonography; Urinary Bladder Neoplasms; Vertigo | 2007 |
Combination antiplatelet therapy with aspirin and clopidogrel: the role of antecedent and concomitant doses of aspirin. An analysis of 711 patients.
Topics: Adult; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Stents; Stroke; Ticlopidine | 2007 |
High post-treatment platelet reactivity is associated with a high incidence of myonecrosis after stenting for non-ST elevation acute coronary syndromes.
Topics: Acute Disease; Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Female; France; Humans; Incidence; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Odds Ratio; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prognosis; Prospective Studies; Research Design; Risk Factors; Stents; Syndrome; Ticlopidine; Time Factors; Troponin I | 2007 |
Safety and efficacy of combined antiplatelet-warfarin therapy after coronary stenting.
Topics: Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Blood Vessel Prosthesis; Clopidogrel; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Prosthesis Failure; Retrospective Studies; Stents; Ticlopidine; Warfarin | 2007 |
Does heart failure etiology, New York Heart Association class, or ejection fraction affect the ability of clopidogrel to inhibit heightened platelet activity?
Topics: Aged; Aged, 80 and over; Aspirin; Biomarkers; Clopidogrel; Drug Evaluation; Female; Heart Failure; Humans; Male; Middle Aged; Myocardial Contraction; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Retrospective Studies; Stroke Volume; Ticlopidine | 2007 |
[Impact of the choice of an antiplatelet therapy for peripheral arterial disease: cost-effectiveness ratio and health economics assessment].
Topics: Aspirin; Clopidogrel; Cost-Benefit Analysis; Humans; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Ticlopidine | 2007 |
CHARISMA: the antiplatelet saga continues.
Topics: Aspirin; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2007 |
[Clopidogrel versus acetylsalicylic acid in the secondary prophylaxis of vascular diseases. A commentary on the report of the Institute for Quality and Efficiency in the Health Service].
Topics: Academies and Institutes; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemotherapy, Adjuvant; Clopidogrel; Humans; National Health Programs; Platelet Aggregation Inhibitors; Quality Assurance, Health Care; Secondary Prevention; Ticlopidine; Vascular Diseases | 2007 |
Persistent platelet activation is related to very early cardiovascular events in patients with acute coronary syndromes.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Disease; Female; Humans; Male; Middle Aged; Multivariate Analysis; Myocardial Ischemia; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Recurrence; Risk Assessment; Syndrome; Ticlopidine | 2007 |
Consistent platelet inhibition during long-term maintenance-dose clopidogrel therapy among 359 compliant outpatients with documented vascular disease.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Flow Cytometry; Humans; Integrin beta3; Male; Middle Aged; Patient Compliance; Platelet Aggregation Inhibitors; Platelet Endothelial Cell Adhesion Molecule-1; Platelet Function Tests; Platelet Membrane Glycoprotein IIb; Risk Factors; Ticlopidine; Vascular Diseases | 2007 |
TNF-alpha and IL-8 in acute stroke and the modulation of these cytokines by antiplatelet agents.
Topics: Acute Disease; Adult; Aged; Aspirin; Brain Ischemia; Cells, Cultured; Clopidogrel; Dipyridamole; Female; Humans; In Vitro Techniques; Interleukin-8; Leukocytes; Male; Middle Aged; Piracetam; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Tumor Necrosis Factor-alpha | 2007 |
Clopidogrel inhibits platelet aggregation in patients on aspirin with stable chronic angina pectoris.
Topics: Angina Pectoris; Aspirin; Chronic Disease; Clopidogrel; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2008 |
Razaxaban, a direct factor Xa inhibitor, in combination with aspirin and/or clopidogrel improves low-dose antithrombotic activity without enhancing bleeding liability in rabbits.
Topics: Animals; Aspirin; Blood Coagulation; Clopidogrel; Disease Models, Animal; Drug Therapy, Combination; Factor Xa; Fibrinolytic Agents; Hemorrhage; Hemostasis; Isoxazoles; Male; Platelet Aggregation; Pyrazoles; Rabbits; Thrombosis; Ticlopidine | 2007 |
Ticlopidine prevents the formation but delays the healing of ethanol-induced gastric lesions in the rat.
Topics: Administration, Oral; Animals; Aspirin; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Gastric Mucosa; Indomethacin; Male; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Ticlopidine; Time Factors; Wound Healing | 2007 |
Internal carotid artery stenosis with ipsilateral persistent hypoglossal artery presenting as a multiterritorial embolic infarction: a case report.
Topics: Aged; Aspirin; Basilar Artery; Brain; Carotid Artery, Internal; Carotid Stenosis; Cerebral Infarction; Clopidogrel; Contrast Media; Diagnosis, Differential; Diffusion Magnetic Resonance Imaging; Female; Humans; Imaging, Three-Dimensional; Intracranial Embolism; Magnetic Resonance Angiography; Platelet Aggregation Inhibitors; Radiography; Rare Diseases; Ticlopidine; Vertigo | 2007 |
Determination of aspirin responsiveness by use of whole blood platelet aggregometry.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Blood Donors; Clopidogrel; Collagen; Coronary Artery Disease; Drug Resistance; Electric Impedance; Female; Humans; In Vitro Techniques; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyridines; Reference Values; Sex Factors; Thromboxane B2; Ticlopidine | 2007 |
Interaction study of aspirin or clopidogrel on pharmacokinetics of donepezil hydrochloride in rats by HPLC-fluorescence detection.
Topics: Administration, Oral; Animals; Aspirin; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid; Clopidogrel; Donepezil; Drug Interactions; Fluorescence; Indans; Injections, Intraperitoneal; Male; Molecular Structure; Piperidines; Rats; Rats, Wistar; Ticlopidine | 2007 |
[Platelet responsiveness to clopidogrel in patients with coronary syndrome. Comparison of platelet aggregation induced by ADP and flow cytometric analysis of intraplatelet VASP phosphorylation].
Topics: Adenosine Diphosphate; Aged; Aspirin; Blood Platelets; Blood Proteins; Cell Adhesion Molecules; Clopidogrel; Drug Resistance; Female; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Follow-Up Studies; Humans; Male; Microfilament Proteins; Myocardial Infarction; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Syndrome; Ticlopidine | 2007 |
Late blood clots tarnish drug-coated stents. Uncommon complication raises questions about who really needs a drug-coated stent and how long to continue drug therapy after getting one.
Topics: Aspirin; Clopidogrel; Coronary Restenosis; Drug Implants; Forecasting; Foreign Bodies; Humans; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine | 2007 |
Double-trouble: three cases with simultaneous stent thrombosis in different coronary arteries.
Topics: Aged; Angioplasty, Balloon; Angioplasty, Balloon, Coronary; Aspirin; Blood Vessel Prosthesis; Clopidogrel; Coronary Thrombosis; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Stents; Ticlopidine; Time Factors | 2007 |
Update on the use of antiplatelet agents in secondary stroke prevention.
Topics: Arteriosclerosis; Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Embolism, Cholesterol; Humans; Platelet Aggregation Inhibitors; Stroke; Thromboembolism; Ticlopidine | 2007 |
Evaluation of the platelet response to clopidogrel with light transmittance aggregometry: peak aggregation or late aggregation?
Topics: Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Clopidogrel; Hematologic Tests; Humans; Light; Platelet Activation; Platelet Aggregation; Platelet Function Tests; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Risk; Ticlopidine | 2007 |
Impact of prior antiplatelet therapy on risk of embolism in infective endocarditis.
Topics: Aged; Aspirin; Clopidogrel; Dipyridamole; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Embolism; Endocarditis, Bacterial; Female; Humans; Incidence; Male; Middle Aged; Platelet Aggregation Inhibitors; Prevalence; Retrospective Studies; Risk Assessment; Stroke; Ticlopidine | 2007 |
Biomarker optimization to track the antithrombotic and hemostatic effects of clopidogrel in rats.
Topics: Adenosine Diphosphate; Animals; Aspirin; Biomarkers; Cell Adhesion Molecules; Clopidogrel; Dose-Response Relationship, Drug; Fibrinolytic Agents; Hemostatics; Male; Membrane Proteins; Microfilament Proteins; Phosphoproteins; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Ticlopidine | 2007 |
Impact of aspirin with or without clopidogrel on postoperative bleeding and blood transfusion in coronary surgical patients treated prophylactically with a low-dose of aprotinin.
Topics: Aged; Aprotinin; Aspirin; Blood Transfusion; Clopidogrel; Coronary Artery Bypass; Drug Therapy, Combination; Female; Hemostatics; Humans; Intraoperative Care; Male; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Prospective Studies; Risk Factors; Ticlopidine | 2007 |
Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
Topics: Aged; Angioplasty, Balloon, Coronary; Anthropometry; Aspirin; Clopidogrel; Coronary Restenosis; Coronary Thrombosis; Death, Sudden, Cardiac; Drug Implants; Drug Utilization; Endothelium, Vascular; Equipment Design; Equipment Failure; Female; Follow-Up Studies; Humans; Hyperplasia; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Paclitaxel; Platelet Aggregation Inhibitors; Sirolimus; Stents; Ticlopidine; Tunica Intima; Wound Healing | 2007 |
Clopidogrel and long-term outcomes after drug-eluting stent implantation.
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Humans; Paclitaxel; Platelet Aggregation Inhibitors; Sirolimus; Stents; Ticlopidine | 2007 |
Clopidogrel and long-term outcomes after drug-eluting stent implantation.
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Humans; Paclitaxel; Platelet Aggregation Inhibitors; Risk Assessment; Sirolimus; Stents; Ticlopidine | 2007 |
Risk of major bleeding with concomitant dual antiplatelet therapy after percutaneous coronary intervention in patients receiving long-term warfarin therapy.
Topics: Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Cohort Studies; Drug Interactions; Drug Therapy, Combination; Female; Follow-Up Studies; Hemorrhage; Humans; Incidence; International Normalized Ratio; Male; Middle Aged; Platelet Aggregation Inhibitors; Proportional Hazards Models; Retrospective Studies; Risk Factors; Ticlopidine; Warfarin | 2007 |
[Interindividual variability in the laboratory response to the aspirin-clopidogrel combination: are patients with stent occlusion "resistant" to treatment?].
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Arachidonic Acid; Aspirin; Clopidogrel; Collagen; Coronary Restenosis; Drug Resistance; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Predictive Value of Tests; Ticlopidine | 2007 |
Increased incidence of stent thrombosis in patients with cocaine use.
Topics: Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Cocaine-Related Disorders; Coronary Angiography; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Follow-Up Studies; Hospitals, Urban; Humans; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Research Design; Retrospective Studies; Risk Assessment; Risk Factors; Stents; Ticlopidine; Time Factors; Treatment Outcome; United States | 2007 |
Platelet aggregometry and receptor binding to predict the magnitude of antithrombotic and bleeding time effects of clopidogrel in rabbits.
Topics: Adenosine Diphosphate; Analysis of Variance; Animals; Aspirin; Biomarkers; Bleeding Time; Blood Platelets; Carotid Artery Thrombosis; Carotid Artery, Common; Clopidogrel; Disease Models, Animal; Dose-Response Relationship, Drug; Hemostasis; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Predictive Value of Tests; Protein Binding; Rabbits; Receptors, Purinergic P2; Regional Blood Flow; Thromboxane B2; Ticlopidine | 2007 |
Patterns of aspirin dosing in non-ST-elevation acute coronary syndromes in the CRUSADE Quality Improvement Initiative.
Topics: Acute Disease; Aged; Aged, 80 and over; Angina, Unstable; Aspirin; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Fibrinolytic Agents; Heart Conduction System; Humans; Male; Middle Aged; Patient Discharge; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Quality of Health Care; Retrospective Studies; Syndrome; Ticlopidine; Treatment Outcome; United States | 2007 |
Measuring aspirin resistance, clopidogrel responsiveness, and postprocedural markers of myonecrosis in patients undergoing percutaneous coronary intervention.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Angioplasty, Balloon, Coronary; Aspirin; Biomarkers; Clopidogrel; Coronary Artery Disease; Creatine Kinase, MB Form; Drug Resistance; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardium; Necrosis; Platelet Aggregation Inhibitors; Platelet Function Tests; Postoperative Period; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Ticlopidine; Treatment Outcome; Troponin I | 2007 |
[Treatment of intrastent restenosis by drug eluting stents: experience from one cardiology centre].
Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Aspirin; Clopidogrel; Coronary Angiography; Coronary Restenosis; Coronary Thrombosis; Equipment Design; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Paclitaxel; Platelet Aggregation Inhibitors; Prospective Studies; Sirolimus; Stents; Surface Properties; Ticlopidine; Treatment Outcome | 2007 |
Factors related to progression of middle cerebral artery stenosis determined using transcranial Doppler ultrasonograhy.
Topics: Adenosine Diphosphate; Aged; Aspirin; Cerebral Angiography; Clopidogrel; Constriction, Pathologic; Disease Progression; Female; Humans; Infarction, Middle Cerebral Artery; Logistic Models; Magnetic Resonance Angiography; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Risk Assessment; Risk Factors; Severity of Illness Index; Ticlopidine; Time Factors; Treatment Outcome; Ultrasonography, Doppler, Transcranial | 2008 |
Factitious anticoagulant-resistance as a cause of recurrent arterial bypass graft occlusions.
Topics: Anticoagulants; Arterial Occlusive Diseases; Aspirin; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Factitious Disorders; Female; Graft Occlusion, Vascular; Heparin, Low-Molecular-Weight; Hirudins; Humans; Iliac Artery; Middle Aged; Munchausen Syndrome; Phenprocoumon; Platelet Aggregation Inhibitors; Recombinant Proteins; Recurrence; Reoperation; Ticlopidine; Treatment Refusal; Vascular Surgical Procedures | 2007 |
Utilisation review of clopidogrel: are they used under the FDA-approved indications?
Topics: Acute Coronary Syndrome; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Cross-Sectional Studies; Drug Therapy, Combination; Drug Utilization Review; Hospitals, University; Humans; Inpatients; Medical Records; Middle Aged; Outpatients; Platelet Aggregation Inhibitors; Retrospective Studies; Thailand; Ticlopidine; United States; United States Food and Drug Administration | 2007 |
Residual platelet reactivity is associated with clinical and laboratory characteristics in patients with ischemic heart disease undergoing PCI on dual antiplatelet therapy.
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Arachidonic Acid; Aspirin; Blood Platelets; Clopidogrel; Female; Humans; Male; Myocardial Ischemia; Platelet Aggregation Inhibitors; Protein Isoforms; Risk Factors; Ticlopidine | 2007 |
Long-term safety and efficacy of drug-eluting stents: two-year results of the REAL (REgistro AngiopLastiche dell'Emilia Romagna) multicenter registry.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Combined Modality Therapy; Coronary Angiography; Coronary Restenosis; Coronary Stenosis; Coronary Thrombosis; Coronary Vessels; Diabetes Mellitus; Drug Implants; Female; Follow-Up Studies; Humans; Incidence; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Paclitaxel; Platelet Aggregation Inhibitors; Proportional Hazards Models; Prospective Studies; Registries; Renal Insufficiency; Risk Factors; Sirolimus; Stents; Ticlopidine; Treatment Outcome | 2007 |
Residual platelet activity is increased in clopidogrel- and ASA-treated patients with coronary stenting for acute coronary syndromes compared with stable coronary artery disease.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Cohort Studies; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Female; Humans; Male; Platelet Activation; Platelet Aggregation Inhibitors; Prospective Studies; Risk Factors; Stents; Ticlopidine; Treatment Outcome | 2008 |
The use of clopidogrel in carotid endarterectomy: an audit of current practice.
Topics: Aspirin; Cerebrovascular Disorders; Clopidogrel; Endarterectomy, Carotid; Hemorrhage; Humans; Medical Audit; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Practice Patterns, Physicians'; Surveys and Questionnaires; Ticlopidine | 2007 |
Comparison of different methods to evaluate the effect of aspirin on platelet function in high-risk patients with ischemic heart disease receiving dual antiplatelet treatment.
Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Arachidonic Acid; Aspirin; Blood Platelets; Clopidogrel; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Sensitivity and Specificity; Ticlopidine | 2007 |
Influence of antiplatelet therapy on cerebral micro-emboli after carotid endarterectomy using postoperative transcranial Doppler monitoring.
Topics: Aged; Anticoagulants; Aspirin; Aspirin, Dipyridamole Drug Combination; Clopidogrel; Dextrans; Dipyridamole; Drug Combinations; Drug Therapy, Combination; Endarterectomy, Carotid; Female; Hemorrhage; Humans; Intracranial Embolism; Ischemic Attack, Transient; Male; Middle Aged; Middle Cerebral Artery; Pilot Projects; Platelet Aggregation Inhibitors; Postoperative Care; Randomized Controlled Trials as Topic; Research Design; Stroke; Ticlopidine; Treatment Outcome; Ultrasonography, Doppler, Transcranial | 2007 |
Duration of clopidogrel therapy after placement of drug-eluting intracoronary stent.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Restenosis; Drug Delivery Systems; Humans; Paclitaxel; Platelet Aggregation Inhibitors; Sirolimus; Stents; Ticlopidine; Time Factors | 2007 |
Relationship between systolic pulsed wave tissue Doppler parameters and both invasive and noninvasive reperfusion criteria in patients with acute anterior myocardial infarction undergoing primary percutaneous coronary intervention.
Topics: Adult; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coronary Angiography; Echocardiography, Doppler, Pulsed; Electrocardiography; Female; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Reperfusion; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Time Factors | 2008 |
[Anticoagulation in atrial fibrillation. ACTIVE Study (Arterial fibrillation Clopidogrel Trial with Irbesartan for Prevention of Vascular Events)].
Topics: Administration, Oral; Angiotensin II Type 1 Receptor Blockers; Aspirin; Atrial Fibrillation; Biphenyl Compounds; Clopidogrel; Drug Therapy, Combination; Follow-Up Studies; Hemorrhage; Humans; Intracranial Embolism; Irbesartan; Myocardial Infarction; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Tetrazoles; Thromboembolism; Ticlopidine | 2007 |
Relationships between optical aggregometry (type born) and flow cytometry in evaluating ADP-induced platelet activation.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy, Combination; Dual Specificity Phosphatase 2; Female; Flow Cytometry; Humans; Image Cytometry; Male; Microfilament Proteins; Middle Aged; P-Selectin; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Reproducibility of Results; Sensitivity and Specificity; Ticlopidine | 2008 |
Spontaneous coronary hematoma during systemic thrombolysis for acute myocardial infarction: intracoronary ultrasound findings, percutaneous coronary intervention and complications.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Aneurysm; Drug Therapy, Combination; Female; Hematoma; Humans; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Thrombolytic Therapy; Ticlopidine; Treatment Outcome; Ultrasonography, Interventional | 2007 |
Do the Behring Coagulation Timer and the Platelet Function Analyzer-100 identify the same patients as being aspirin non-responders?
Topics: Aged; Arterial Occlusive Diseases; Aspirin; Automation; Blood Platelets; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2007 |
PCI for stable coronary disease.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Combined Modality Therapy; Coronary Disease; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine | 2007 |
[Spontaneous internal carotid artery dissection with paralysis of lower cranial nerves].
Topics: Aspirin; Carotid Artery, Internal, Dissection; Clopidogrel; Cranial Nerve Diseases; Humans; Paralysis; Platelet Aggregation Inhibitors; Prognosis; Ticlopidine | 2007 |
Case report on clopidogrel rash after coronary placement of a paclitaxol-coated stent.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Stenosis; Disease Progression; Drug Hypersensitivity; Drug Therapy, Combination; Exanthema; Humans; Male; Middle Aged; Paclitaxel; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Tubulin Modulators; Urticaria | 2007 |
[After coronary intervention. Which platelet inhibitor for whom?].
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coated Materials, Biocompatible; Coronary Disease; Cost Control; Drug Costs; Drug Therapy, Combination; Germany; Humans; Myocardial Infarction; National Health Programs; Platelet Aggregation Inhibitors; Secondary Prevention; Stents; Ticlopidine | 2007 |
[Coronary heart disease patient does not tolerate acetylsalicylic acid. Can clopidogrel be prescribed?].
Topics: Aspirin; Clopidogrel; Contraindications; Coronary Disease; Drug Therapy, Combination; Humans; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2007 |
Aggressive antiplatelet strategies: time to reconsider?
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine | 2007 |
[Modified platelet aggregation test in patients on ASA and/or clopidogrel].
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Clopidogrel; Collagen; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epinephrine; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Reference Values; Thrombosis; Ticlopidine | 2007 |
Drug-eluting stents: dual antiplatelet therapy for every survivor?
Topics: Algorithms; Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Incidence; Paclitaxel; Platelet Aggregation Inhibitors; Pyridines; Sirolimus; Stents; Survivors; Thrombosis; Ticlopidine | 2007 |
Drug drug interactions between antithrombotic medications and the risk of gastrointestinal bleeding.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Clopidogrel; Drug Interactions; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine; Warfarin | 2007 |
An economic analysis of aspirin desensitization in aspirin-exacerbated respiratory disease.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cardiovascular Diseases; Clopidogrel; Cost-Benefit Analysis; Desensitization, Immunologic; Drug Hypersensitivity; Humans; Markov Chains; Middle Aged; Models, Biological; Platelet Aggregation Inhibitors; Quality-Adjusted Life Years; Respiration Disorders; Ticlopidine | 2008 |
Perioperative thrombotic risk of coronary artery stents: possible role for intravenous platelet blockade.
Topics: Aspirin; Clopidogrel; Coronary Thrombosis; Humans; Injections, Intravenous; Perioperative Care; Platelet Aggregation Inhibitors; Postoperative Complications; Risk Factors; Stents; Ticlopidine; Tirofiban; Tyrosine | 2007 |
Admissions to a medical intensive care unit related to adverse drug reactions.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Drug-Related Side Effects and Adverse Reactions; Female; Hemorrhage; Hospitalization; Hospitals, Teaching; Humans; Intensive Care Units; Male; Platelet Aggregation Inhibitors; Ticlopidine | 2007 |
Clopidogrel: new indication. In combination with aspirin: marginal additional benefits.
Topics: Aspirin; Clinical Trials as Topic; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors; Treatment Outcome | 2007 |
[Treatment of carotid artery aneurysms with covered stents].
Topics: Adult; Alloys; Angiography, Digital Subtraction; Angioplasty; Aortic Dissection; Aspirin; Carotid Artery Diseases; Carotid Artery, External; Cerebral Angiography; Clopidogrel; Female; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Platelet Aggregation Inhibitors; Polytetrafluoroethylene; Stents; Ticlopidine; Time Factors; Tomography, X-Ray Computed; Treatment Outcome | 2007 |
The "clopidogrel resistance" trap.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Humans; Patient Compliance; Platelet Aggregation Inhibitors; Ticlopidine | 2007 |
A thromboxane A2/prostaglandin H2 receptor antagonist (S18886) shows high antithrombotic efficacy in an experimental model of stent-induced thrombosis.
Topics: Administration, Oral; Animals; Aorta; Aspirin; Bleeding Time; Blood Coagulation; Clopidogrel; Disease Models, Animal; Fibrin; Fibrinogen; Fibrinolytic Agents; Hemorrhage; Naphthalenes; Platelet Activation; Platelet Aggregation Inhibitors; Propionates; Prosthesis Design; Receptors, Thromboxane A2, Prostaglandin H2; Stainless Steel; Stents; Swine; Thrombosis; Ticlopidine; Time Factors | 2007 |
Is clopidogrel stopped prior to hip fracture surgery--A survey of current practice in the United Kingdom.
Topics: Anticoagulants; Aspirin; Clinical Protocols; Clopidogrel; Contraindications; Femoral Neck Fractures; Health Care Surveys; Humans; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Preoperative Care; Professional Practice; Surgery Department, Hospital; Ticlopidine; United Kingdom; Warfarin | 2007 |
Antiplatelet drug therapy moderates immune-mediated liver disease and inhibits viral clearance in mice infected with a replication-deficient adenovirus.
Topics: Adenoviridae; Adenoviridae Infections; Animals; Aspirin; Clopidogrel; Defective Viruses; Immune System Diseases; Leukocytes; Liver; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Platelet Aggregation Inhibitors; T-Lymphocytes, Cytotoxic; Ticlopidine | 2007 |
The impact of oral antiplatelet responsiveness on the long-term prognosis after coronary stenting.
Topics: Aged; Aspirin; Clopidogrel; Coronary Angiography; Creatine Kinase, MB Form; Drug Therapy, Combination; Drug Tolerance; Female; Hospitalization; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Platelet Aggregation Inhibitors; Prognosis; Prospective Studies; Secondary Prevention; Stents; Ticlopidine | 2007 |
Dual antiplatelet agent failure: a new syndrome or clinical nonentity?
Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Prognosis; Recurrence; Syndrome; Ticlopidine; Treatment Outcome | 2007 |
Perioperative management of anticoagulant therapy during cutaneous surgery: 2005 survey of Mohs surgeons.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Clopidogrel; Dermatology; Drug Utilization Review; Humans; Mohs Surgery; Perioperative Care; Practice Patterns, Physicians'; Skin Diseases; Surveys and Questionnaires; Ticlopidine; United States; Vitamin E; Warfarin | 2007 |
Triple antithrombotic therapy with aspirin, clopidogrel and warfarin--a persisting dilemma.
Topics: Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Thrombosis; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Risk Factors; Ticlopidine; Venous Thrombosis; Warfarin | 2007 |
Evaluation of platelet and leukocyte functions in effort angina patients using high shear conditions in small-sized collagen bead columns.
Topics: Aged; Angina Pectoris; Aspirin; Blood Platelets; Case-Control Studies; Collagen; Female; Hemorheology; Humans; In Vitro Techniques; L-Selectin; Leukocytes; Male; Middle Aged; P-Selectin; Particle Size; Platelet Aggregation Inhibitors; Platelet Function Tests; Solubility; Stents; Ticlopidine | 2007 |
Clopidogrel in addition to aspirin reduces one-year major adverse cardiac and cerebrovascular events in unselected patients with non-ST segment elevation myocardial infarction.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Comorbidity; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Platelet Aggregation Inhibitors; Prognosis; Secondary Prevention; Stroke; Ticlopidine | 2008 |
Guideline-based discharge therapy for unstable angina pectoris/non-ST elevation myocardial infarction.
Topics: Angina, Unstable; Aspirin; Clopidogrel; Electrocardiography; Humans; Hypolipidemic Agents; Myocardial Infarction; Patient Discharge; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Ticlopidine; Time Factors | 2007 |
Safety of the cardiac triple therapy: the experience of the Quebec Heart Institute.
Topics: Acute Coronary Syndrome; Aged; Anticoagulants; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Fibrinolytic Agents; Hemorrhage; Humans; Male; Platelet Aggregation Inhibitors; Quebec; Retrospective Studies; Risk Factors; Ticlopidine; Warfarin | 2007 |
Impact of platelet reactivity on cardiovascular outcomes in patients with type 2 diabetes mellitus and coronary artery disease.
Topics: Aged; Angina, Unstable; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Death, Sudden, Cardiac; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Humans; Male; Multivariate Analysis; Myocardial Infarction; Outcome Assessment, Health Care; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Predictive Value of Tests; Prognosis; Prospective Studies; Renal Insufficiency; ROC Curve; Sensitivity and Specificity; Stroke; Ticlopidine | 2007 |
Sweet and sticky: diabetic platelets, enhanced reactivity, and cardiovascular risk.
Topics: Angina, Unstable; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Death, Sudden, Cardiac; Diabetes Mellitus, Type 2; Humans; Myocardial Infarction; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Prognosis; Stroke; Ticlopidine | 2007 |
Platelets and stents.
Topics: Angioplasty; Aspirin; Clopidogrel; Combined Modality Therapy; Humans; Intracranial Arteriosclerosis; Platelet Aggregation Inhibitors; Radiography; Stents; Ticlopidine | 2007 |
The CAPRIE-like subgroups of CHARISMA: a CAPRIEciously biased analysis of an unCHARISMAtic truth.
Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Humans; Myocardial Ischemia; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Research Design; Ticlopidine; Treatment Outcome | 2007 |
Effectiveness and safety of reduced-dose enoxaparin in non-ST-segment elevation acute coronary syndrome followed by antiplatelet therapy alone for percutaneous coronary intervention.
Topics: Acute Coronary Syndrome; Aged; Anticoagulants; Aspirin; Atherectomy, Coronary; Clopidogrel; Coronary Angiography; Drug Therapy, Combination; Enoxaparin; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Stents; Ticlopidine | 2007 |
[Antithrombotic therapy in ischemic stroke and transient ischemic attack].
Topics: Aspirin; Brain Ischemia; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Recurrence; Stroke; Thromboembolism; Ticlopidine | 2007 |
Post-stenting antithrombotic drug therapy in patients with atrial fibrillation.
Topics: Aspirin; Atrial Fibrillation; Clopidogrel; Fibrinolytic Agents; Humans; Practice Guidelines as Topic; Risk Factors; Stents; Thrombosis; Ticlopidine; Warfarin | 2007 |
Intensifying platelet inhibition--navigating between Scylla and Charybdis.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Ischemia; Piperazines; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Ticlopidine | 2007 |
Letter by Fisher and Johns regarding article, "Variable platelet response to aspirin and clopidogrel in atherothrombotic disease".
Topics: Aspirin; Atherosclerosis; Blood Platelets; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Tablets, Enteric-Coated; Ticlopidine | 2007 |
P2Y12 polymorphisms and antiplatelet effects of aspirin in patients with coronary artery disease.
Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Female; Genotype; Haplotypes; Humans; Male; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Ticlopidine; Treatment Outcome | 2008 |
Cytochrome P450 2C19 loss-of-function polymorphism, but not CYP3A4 IVS10 + 12G/A and P2Y12 T744C polymorphisms, is associated with response variability to dual antiplatelet treatment in high-risk vascular patients.
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Alleles; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Humans; Male; Middle Aged; Mixed Function Oxygenases; Pharmacogenetics; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Ticlopidine | 2007 |
Endovascular treatment of a renal artery stenosis: techniques, indications, results. Role of embolic protection devices (part 2).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Catheterization; Clopidogrel; Embolism; Fibrinolytic Agents; Heparin; Hirudins; Humans; Peptide Fragments; Platelet Aggregation Inhibitors; Recombinant Proteins; Renal Artery Obstruction; Ticlopidine | 2007 |
Clopidogrel versus aspirin in patients with atherothrombosis: CAPRIE-based calculation of cost-effectiveness for Germany.
Topics: Aged; Aged, 80 and over; Aspirin; Atherosclerosis; Clopidogrel; Cohort Studies; Coronary Thrombosis; Cost-Benefit Analysis; Germany; Humans; Models, Econometric; Myocardial Infarction; Platelet Aggregation Inhibitors; Survival Analysis; Ticlopidine; Treatment Outcome | 2008 |
Multimodal thromboprophylaxis for total hip and knee arthroplasty based on risk assessment.
Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Aspirin; Clopidogrel; Combined Modality Therapy; Dipyridamole; Early Ambulation; Enoxaparin; Female; Fibrinolytic Agents; Hematologic Agents; Humans; Intermittent Pneumatic Compression Devices; Male; Middle Aged; Platelet Aggregation Inhibitors; Pulmonary Embolism; Retrospective Studies; Risk Assessment; Thromboembolism; Ticlopidine; Venous Thrombosis; Warfarin | 2007 |
Coronary artery in-stent stenosis persists despite inhibition of the von Willebrand factor--collagen interaction in baboons.
Topics: Angioplasty, Balloon, Coronary; Animals; Antibodies, Monoclonal; Aspirin; Clopidogrel; Collagen; Coronary Stenosis; Coronary Vessels; Disease Models, Animal; Drug Therapy, Combination; Fibrinolytic Agents; Heparin; Male; Papio ursinus; Platelet Adhesiveness; Stents; Ticlopidine; Time Factors; Tunica Intima; von Willebrand Factor | 2007 |
Expression of platelet surface receptors and early changes in platelet function in patients with STEMI treated with abciximab and clopidogrel versus clopidogrel alone.
Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Humans; Immunoglobulin Fab Fragments; Integrin beta3; Male; Middle Aged; Myocardial Infarction; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoprotein IIb; Ticlopidine | 2007 |
2007 Focused update of the ACC/AHA/SCAI 2005 guideline update for percutaneous coronary intervention. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.
Topics: Acute Coronary Syndrome; Angina, Unstable; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Chronic Disease; Clopidogrel; Contraindications; Coronary Angiography; Coronary Artery Bypass; Coronary Disease; Coronary Stenosis; Drug-Eluting Stents; Electrocardiography; Evidence-Based Medicine; Exercise Test; Humans; Kidney Diseases; Myocardial Infarction; Nomograms; Patient Selection; Platelet Aggregation Inhibitors; Prognosis; Radionuclide Ventriculography; Randomized Controlled Trials as Topic; Recurrence; Risk Assessment; Stents; Stroke Volume; Thrombolytic Therapy; Ticlopidine | 2008 |
The effect of platelet-altering medications on bleeding from minor oral surgery procedures.
Topics: Analysis of Variance; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Blood Platelets; Case-Control Studies; Clopidogrel; Humans; Oral Surgical Procedures; Platelet Aggregation; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Prospective Studies; Ticlopidine | 2008 |
Iliac venous stenting: antithrombotic efficacy of PD0348292, an oral direct Factor Xa inhibitor, compared with antiplatelet agents in pigs.
Topics: Administration, Oral; Angioplasty; Animals; Antithrombin III; Aspirin; Clopidogrel; Constriction, Pathologic; Disease Models, Animal; Drug Therapy, Combination; Female; Iliac Vein; Preoperative Care; Probability; Pyridones; Pyrrolidines; Random Allocation; Reference Values; Stents; Ticlopidine; Treatment Outcome; Vascular Patency; Venous Thrombosis | 2008 |
Late stent thrombosis in patients receiving ticlopidine and aspirin after sirolimus-eluting stent implantation.
Topics: Aged; Aspirin; Drug Therapy, Combination; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Incidence; Male; Middle Aged; Sirolimus; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2008 |
Anti-platelet agents and surgical delay in elderly patients with hip fractures.
Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Female; Hip Fractures; Humans; Male; Platelet Aggregation Inhibitors; Platelet Count; Retrospective Studies; Ticlopidine; Time Factors | 2007 |
Aspirin + clopidogrel therapy: how does your care compare to the evidence?
Topics: Acute Coronary Syndrome; Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Evidence-Based Medicine; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Secondary Prevention; Stroke; Thrombosis; Ticlopidine | 2008 |
Antiplatelet agents for stroke prevention following transient ischemic attack.
Topics: Angioplasty, Balloon; Aspirin; Carotid Artery Diseases; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Endarterectomy, Carotid; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Stents; Stroke; Ticlopidine | 2008 |
Gastrointestinal bleeding in patients receiving a combination of aspirin, clopidogrel, and enoxaparin in acute coronary syndrome.
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Clopidogrel; Drug Therapy, Combination; Enoxaparin; Female; Gastrointestinal Hemorrhage; Humans; Logistic Models; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Statistics, Nonparametric; Ticlopidine | 2008 |
Prediction and prevention of stroke in patients with symptomatic carotid stenosis: the high-risk period and the high-risk patient.
Topics: Aspirin; Carotid Stenosis; Clopidogrel; Endarterectomy, Carotid; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Prognosis; Recurrence; Risk Assessment; Stroke; Ticlopidine; Time Factors | 2008 |
Coronary artery stenting in patients treated by clopidogrel without aspirin.
Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Stents; Thrombosis; Ticlopidine | 2009 |
Standardization of light transmittance aggregometry for monitoring antiplatelet therapy: an adjustment for platelet count is not necessary.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Algorithms; Arachidonic Acid; Aspirin; Calibration; Clopidogrel; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Nephelometry and Turbidimetry; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Platelet-Rich Plasma; Sensitivity and Specificity; Thrombophilia; Ticlopidine | 2008 |
Outcomes associated with combined antiplatelet and anticoagulant therapy.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Clopidogrel; Cohort Studies; Coronary Artery Disease; Dipyridamole; Drug Therapy, Combination; Female; Hemorrhage; Humans; Longitudinal Studies; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Thromboembolism; Ticlopidine; Treatment Outcome; Warfarin | 2008 |
Portal vein thrombosis associated with coronary artery bypass surgery.
Topics: Aged; Aspirin; Bacteremia; Clopidogrel; Coagulase; Coronary Artery Bypass; Esophageal and Gastric Varices; Fatal Outcome; Gastrointestinal Hemorrhage; Humans; Male; Platelet Aggregation Inhibitors; Portal Vein; Staphylococcus; Ticlopidine; Tomography, X-Ray Computed; Treatment Failure; Treatment Outcome; Venous Thrombosis | 2008 |
Clopidogrel in addition to aspirin reduces in-hospital major cardiac and cerebrovascular events in unselected patients with acute ST segment elevation myocardial.
Topics: Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Cerebrovascular Disorders; Clopidogrel; Drug Therapy, Combination; Female; Heart Diseases; Hemorrhage; Hospital Mortality; Hospitalization; Humans; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Platelet Aggregation Inhibitors; Research Design; Retrospective Studies; Risk Assessment; Risk Factors; Secondary Prevention; Stroke; Thrombolytic Therapy; Ticlopidine; Time Factors; Treatment Outcome | 2008 |
Effect of chronic treatment with acetylsalicylic acid and clopidogrel on atheroprogression and atherothrombosis in ApoE-deficient mice in vivo.
Topics: Animals; Aorta; Apolipoproteins E; Aspirin; Atherosclerosis; Blood Platelets; Carotid Arteries; Cholesterol, Dietary; Clopidogrel; Disease Models, Animal; Disease Progression; Drug Administration Schedule; Drug Therapy, Combination; Endothelial Cells; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Fluorescence; Microscopy, Video; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Rupture; Thrombosis; Ticlopidine; Time Factors | 2008 |
Analysis of the upper gastrointestinal tract bleeding prevalence in patients treated due ischaemic heart disease.
Topics: Acenocoumarol; Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Body Mass Index; Clopidogrel; Female; Gastrointestinal Tract; Hemorrhage; Humans; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation Inhibitors; Ticlopidine | 2007 |
STOPP (Screening Tool of Older Person's Prescriptions) and START (Screening Tool to Alert doctors to Right Treatment). Consensus validation.
Topics: Abbreviations as Topic; Age Factors; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bendroflumethiazide; Clopidogrel; Delphi Technique; Digoxin; Diuretics; Drug Prescriptions; Drug Therapy; Drug Utilization Review; Drug-Related Side Effects and Adverse Reactions; Glomerular Filtration Rate; Health Services for the Aged; Humans; Ireland; Metformin; Practice Patterns, Physicians'; Reproducibility of Results; Risk Factors; Ticlopidine; Time Factors; United Kingdom | 2008 |
Markers of electrophilic stress caused by chemically reactive metabolites in human hepatocytes.
Topics: Acetaminophen; Aspirin; Butylated Hydroxyanisole; Carboxylic Ester Hydrolases; Cells, Cultured; Clozapine; Diclofenac; Furosemide; Glucuronosyltransferase; Heme Oxygenase-1; Hepatocytes; Humans; L-Lactate Dehydrogenase; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; RNA, Messenger; Ticlopidine; Ticrynafen | 2008 |
Combined antithrombotic therapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Clopidogrel; Drug Interactions; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine; Warfarin | 2008 |
I had a drug-coated stent implanted in one of my coronary arteries. I have been taking aspirin and Plavix daily since the procedure. What determines the appropriate time for discontinuing these medications? Are there any negative aspects to continuing the
Topics: Aspirin; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2007 |
Management of upper gastrointestinal haemorrhage complicating dual anti-platelet therapy.
Topics: Aged; Aspirin; Blood Transfusion; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Endoscopy, Gastrointestinal; Female; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibitors; Platelet Count; Randomized Controlled Trials as Topic; Ticlopidine; Treatment Outcome | 2008 |
The Cataract National Dataset electronic multicentre audit of 55,567 operations: antiplatelet and anticoagulant medications.
Topics: Aged; Anesthetics, Local; Anticoagulants; Aspirin; Blood Loss, Surgical; Cataract Extraction; Choroid Hemorrhage; Clopidogrel; Dipyridamole; Eye Hemorrhage; Humans; Intraoperative Complications; Lens Capsule, Crystalline; Platelet Aggregation Inhibitors; Risk Factors; Rupture; Ticlopidine; Warfarin | 2009 |
Very late thrombosis in a bare metal stent: an under-recognized problem.
Topics: Aspirin; Clopidogrel; Coronary Angiography; Coronary Restenosis; Coronary Thrombosis; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Stents; Thrombectomy; Ticlopidine | 2008 |
Which patients receiving warfarin can be treated safely with a drug-eluting stent?
Topics: Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coronary Restenosis; Coronary Thrombosis; Drug-Eluting Stents; Humans; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Stroke; Ticlopidine; Warfarin | 2008 |
How to optimise clopidogrel therapy? Reducing the low-response incidence by aggregometry-guided therapy modification.
Topics: Adenosine Diphosphate; Aged; Algorithms; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Cardiovascular Diseases; Clinical Protocols; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Monitoring; Drug Resistance; Feasibility Studies; Female; Humans; Male; Middle Aged; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Stents; Ticlopidine | 2008 |
Aspirin and clopidogrel use in the perioperative period for non-cardiac surgery.
Topics: Aspirin; Blood Loss, Surgical; Clopidogrel; Drug-Eluting Stents; Humans; Intraoperative Complications; Medical History Taking; Perioperative Care; Platelet Aggregation Inhibitors; Risk Assessment; Risk Factors; Ticlopidine | 2008 |
Internal carotid artery stenting for blunt carotid artery injuries with an associated pseudoaneurysm.
Topics: Accidents, Traffic; Adolescent; Adult; Aneurysm, False; Aspirin; Carotid Artery Injuries; Carotid Artery, Internal; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Stents; Ticlopidine; Tomography, X-Ray Computed; Wounds, Nonpenetrating | 2008 |
Evidence for prolonged prescribing of aspirin-clopidogrel combination in Scottish primary care.
Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Cross-Sectional Studies; Drug Therapy, Combination; Female; Humans; Male; Platelet Aggregation Inhibitors; Population Surveillance; Primary Health Care; Retrospective Studies; Scotland; Ticlopidine | 2008 |
Rapid oral aspirin desensitization for patients with aspirin allergy requiring dual antiplatelet therapy.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Hypersensitivity; Drug Therapy, Combination; Humans; Inactivation, Metabolic; Membrane Proteins; Platelet Aggregation Inhibitors; Receptors, Leukotriene; Ticlopidine | 2008 |
Prevention of thrombosis in polycythemia vera and essential thrombocythemia.
Topics: Arterial Occlusive Diseases; Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; Hydroxyurea; Janus Kinase 2; Multicenter Studies as Topic; Phlebotomy; Polycythemia Vera; Retrospective Studies; Risk Factors; Severity of Illness Index; Thrombocythemia, Essential; Thrombophilia; Thrombosis; Ticlopidine; Venous Thrombosis | 2008 |
Update to the AHA/ASA recommendations for the prevention of stroke in patients with stroke and transient ischemic attack.
Topics: Aspirin; Brain Ischemia; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Drug Combinations; Drug Therapy, Combination; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Secondary Prevention; Stroke; Ticlopidine | 2008 |
Trends in usage of alternative antiplatelet therapy after stroke and transient ischemic attack.
Topics: Aged; Aged, 80 and over; Aspirin; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Drug Prescriptions; Drug Therapy, Combination; Female; Humans; Ischemic Attack, Transient; Male; Marketing of Health Services; Middle Aged; Platelet Aggregation Inhibitors; Registries; Stroke; Ticlopidine; United States | 2008 |
Antiplatelet therapy in acute coronary syndrome: not as confusing as you think.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Bypass; Emergency Service, Hospital; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2008 |
Effects of diabetes mellitus on platelet reactivity after dual antiplatelet therapy with aspirin and clopidogrel.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Cohort Studies; Coronary Artery Disease; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Humans; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Thrombosis; Ticlopidine; Treatment Outcome | 2008 |
Very very late thrombosis of a sirolimus-eluting stent: does suboptimal stent expansion take its toll even after three years?
Topics: Aspirin; Clopidogrel; Coronary Thrombosis; Drug-Eluting Stents; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Radiography; Reoperation; Sirolimus; Ticlopidine; Time Factors | 2008 |
Simultaneous subacute coronary drug-eluting stent thrombosis in two different vessels of a patient with factor V Leiden mutation.
Topics: Angioplasty, Balloon; Anticoagulants; Aspirin; Clopidogrel; Coronary Angiography; Coronary Thrombosis; Drug-Eluting Stents; Factor V; Humans; Male; Middle Aged; Mutation; Paclitaxel; Platelet Aggregation Inhibitors; Sirolimus; Ticlopidine; Warfarin | 2008 |
[Intravitreal injections during anticoagulant treatment].
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticoagulants; Aspirin; Bevacizumab; Choroidal Neovascularization; Clopidogrel; Conjunctival Diseases; Humans; Injections; Intracranial Hemorrhages; Macular Degeneration; Phenprocoumon; Platelet Aggregation Inhibitors; Prospective Studies; Ranibizumab; Risk Factors; Ticlopidine; Triamcinolone; Vitreous Body; Vitreous Hemorrhage | 2008 |
A critically severe gingival bleeding following non-surgical periodontal treatment in patients medicated with anti-platelet.
Topics: Aspirin; Clopidogrel; Drug Combinations; Female; Gingival Hemorrhage; Humans; Middle Aged; Periodontitis; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Root Planing; Shock; Ticlopidine | 2008 |
Prasugrel versus clopidogrel.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Humans; Monitoring, Physiologic; Myocardial Infarction; Piperazines; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Thiophenes; Ticlopidine | 2008 |
Common blood thinners: what are the differences?
Topics: Anticoagulants; Aspirin; Clopidogrel; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Drug Utilization; Emergency Nursing; Emergency Service, Hospital; Humans; Monitoring, Physiologic; Risk Assessment; Sensitivity and Specificity; Ticlopidine; Warfarin | 2008 |
Monitoring the efficacy of antiplatelet therapy: all methods are equal, but some methods are more equal than others?
Topics: Aspirin; Clopidogrel; Drug Monitoring; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Function Tests; Prognosis; Stents; Ticlopidine | 2008 |
Current challenges and directions in antithrombotic therapy.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2008 |
Comparison of PD0348292, a selective factor Xa inhibitor, to antiplatelet agents for the inhibition of arterial thrombosis.
Topics: Administration, Oral; Animals; Aspirin; Bleeding Time; Blood Coagulation; Carotid Artery Injuries; Carotid Artery Thrombosis; Clopidogrel; Disease Models, Animal; Factor Xa Inhibitors; Female; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyridones; Pyrrolidines; Sus scrofa; Thrombosis; Ticlopidine | 2008 |
Unilateral idiopathic adrenal hematomas with a preoperative diagnosis of indeterminate adrenal tumors.
Topics: Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenalectomy; Aged; Anemia; Aspirin; Clopidogrel; Coronary Artery Disease; Diagnosis, Differential; Female; Hematoma; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Preoperative Care; Retrospective Studies; Stents; Ticlopidine | 2008 |
Stent thrombosis--a complication best avoided.
Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clopidogrel; Coronary Thrombosis; Drug-Eluting Stents; Heparin; Humans; Immunoglobulin Fab Fragments; Platelet Aggregation Inhibitors; Risk Factors; Thrombectomy; Ticlopidine | 2008 |
Percutaneous coronary intervention in neurosurgical patients.
Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coronary Thrombosis; Female; Humans; Male; Middle Aged; Neurosurgical Procedures; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2008 |
Resistance to platelet antiaggregants: an important cause of very late thrombosis of drug eluting stents? Observations from five cases.
Topics: Aged; Aged, 80 and over; Aspirin; Cell Adhesion Molecules; Clopidogrel; Coronary Thrombosis; Drug Resistance; Drug-Eluting Stents; Female; Fibrinolytic Agents; Flow Cytometry; Humans; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Ticlopidine | 2008 |
Acute stent thrombosis in a patient with giant cell arteritis.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Thrombosis; Giant Cell Arteritis; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Prednisone; Stents; Ticlopidine | 2008 |
Platelet activation and atherothrombosis.
Topics: Acute Coronary Syndrome; Aspirin; Atherosclerosis; Clopidogrel; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Activation; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine; Vascular Diseases | 2008 |
[Antiplatelet treatment after acute and chronic ischemic heart and brain events is insufficient according to recommendations].
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Angina Pectoris; Angina, Unstable; Aspirin; Brain Infarction; Brain Ischemia; Clopidogrel; Diabetes Mellitus; Dipyridamole; Drug Therapy, Combination; Female; Guideline Adherence; Humans; Ischemic Attack, Transient; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine | 2008 |
Antithrombotic therapy in peripheral arterial disease.
Topics: Anticoagulants; Aspirin; Atherosclerosis; Cilostazol; Clopidogrel; Comorbidity; Diabetic Angiopathies; Humans; Hypertension; Intermittent Claudication; Pentoxifylline; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Risk Factors; Smoking; Tetrazoles; Thrombolytic Therapy; Ticlopidine | 2008 |
What anti-thrombotic therapy is best with primary PCI for acute ST elevation myocardial infarction: how should the HORIZONS trial change current practice?
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Cardiovascular Diseases; Clopidogrel; Fibrinolytic Agents; Hemorrhage; Heparin; Hirudins; Humans; Myocardial Infarction; Patient Selection; Peptide Fragments; Platelet Glycoprotein GPIIb-IIIa Complex; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Recombinant Proteins; Research Design; Stents; Thrombin; Thrombosis; Ticlopidine; Treatment Outcome | 2008 |
Single antiplatelet therapy for patients with previous gastrointestinal bleeds.
Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Humans; Male; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Randomized Controlled Trials as Topic; Recurrence; Ticlopidine | 2008 |
Correction to the PRoFESS Trial paper by Diener et al. (Cerebrovasc Dis 2007;23:368-80.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Aspirin, Dipyridamole Drug Combination; Benzimidazoles; Benzoates; Clopidogrel; Data Interpretation, Statistical; Delayed-Action Preparations; Dipyridamole; Drug Combinations; Drug Interactions; Humans; Platelet Aggregation Inhibitors; Telmisartan; Ticlopidine | 2008 |
Observance of antiplatelet therapy after stent implantation in patients under chronic oral anticoagulant treatment.
Topics: Administration, Oral; Aged; Anticoagulants; Aspirin; Blood Vessel Prosthesis Implantation; Clopidogrel; Drug Delivery Systems; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Patient Compliance; Platelet Aggregation Inhibitors; Stents; Survival Analysis; Thrombosis; Ticlopidine; Treatment Outcome | 2008 |
Consensus document on intermittent claudication from the Central European Vascular Forum 1st edition - Abano Terme (Italy) - May 2005 2nd revision - Portroz (Slovenia) September 2007.
Topics: Aspirin; Carotid Stenosis; Clopidogrel; Disease Progression; Exercise Test; Humans; Intermittent Claudication; Ischemia; Leg; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Ticlopidine; Ultrasonography, Doppler, Color | 2008 |
Glycoprotein IIb/IIIa receptor inhibition with abciximab during percutaneous coronary interventions increases the risk of bleeding in patients with impaired renal function.
Topics: Abciximab; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Germany; Glomerular Filtration Rate; Hemorrhage; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Renal Insufficiency; Retrospective Studies; Surveys and Questionnaires; Survival Analysis; Ticlopidine | 2008 |
A new self-expandable nitinol stent for the treatment of wide-neck aneurysms: initial clinical experience.
Topics: Adult; Aged; Alloys; Aneurysm, Ruptured; Aspirin; Cerebral Angiography; Clopidogrel; Combined Modality Therapy; Computer Simulation; Embolization, Therapeutic; Equipment Design; Female; Follow-Up Studies; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Intracranial Aneurysm; Male; Middle Aged; Platelet Aggregation Inhibitors; Premedication; Retreatment; Stents; Subarachnoid Hemorrhage; Ticlopidine | 2008 |
Anti-platelet agents and surgical delay in elderly patients with hip fractures.
Topics: Aged; Aspirin; Bleeding Time; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Hip Fractures; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2008 |
Drug-eluting stent implantation for acute myocardial infarction during pregnancy with use of glycoprotein IIb/IIIa inhibitor, aspirin and clopidogrel.
Topics: Aspirin; Clopidogrel; Coronary Angiography; Drug-Eluting Stents; Electrocardiography; Female; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pregnancy; Pregnancy Complications, Cardiovascular; Prosthesis Implantation; Ticlopidine; Treatment Outcome | 2008 |
Aspirin non-responsiveness in Korean subjects on dual anti-platelet treatment determined by two different platelet function assays.
Topics: Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Asian People; Aspirin; Bleeding Time; Case-Control Studies; Clopidogrel; Collagen; Drug Resistance; Epinephrine; Female; Humans; Korea; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2008 |
A case of widespread livedoid vasculopathy with pain but no systemic symptoms.
Topics: Adult; Alprostadil; Aspirin; Biopsy; Blood Sedimentation; C-Reactive Protein; Female; Humans; Hyperesthesia; Lymphocytes; Platelet Aggregation Inhibitors; Skin; Skin Diseases, Vascular; Ticlopidine; Vasodilator Agents | 2008 |
Dual antiplatelet therapy monitoring for neurointerventional procedures using a point-of-care platelet function test: a single-center experience.
Topics: Adult; Aged; Angioplasty, Balloon; Aspirin; Cerebrovascular Disorders; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Embolization, Therapeutic; Female; Humans; Intracranial Embolism; Intracranial Thrombosis; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Predictive Value of Tests; Prospective Studies; Stents; Ticlopidine | 2008 |
[Emergency treatment of transient cerebral ischemia].
Topics: Aspirin; Clopidogrel; Emergency Treatment; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Risk Factors; Stroke; Ticlopidine | 2008 |
Relationship between aspirin and clopidogrel responses in acute coronary syndrome and clinical predictors of non response.
Topics: Acute Coronary Syndrome; Age Factors; Aged; Arachidonic Acid; Aspirin; Body Mass Index; Cell Adhesion Molecules; Clopidogrel; Diabetes Complications; Drug Resistance; Humans; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2009 |
Statins do not adversely affect post-interventional residual platelet aggregation and outcomes in patients undergoing coronary stenting treated by dual antiplatelet therapy.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Coronary Stenosis; Cytochrome P-450 CYP3A; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prognosis; Stents; Ticlopidine | 2008 |
Adverse events associated with stopping clopidogrel after acute coronary syndrome.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Risk; Ticlopidine | 2008 |
Antiaggregant and anticoagulant therapy of free-floating thrombus in left atrium.
Topics: Adult; Anticoagulants; Aspirin; Clopidogrel; Diagnosis, Differential; Dyspnea; Echocardiography, Transesophageal; Female; Heart Atria; Heart Diseases; Heparin; Humans; Platelet Aggregation Inhibitors; Radiography; Thrombosis; Ticlopidine; Warfarin | 2008 |
[Dual antiplatelet drug resistance in a patient allergic to clopidogrel: a case report].
Topics: Aged; Aspirin; Clopidogrel; Drug Resistance; Female; Humans; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2008 |
Unplanned surgery after drug eluting stent implantation: a strategy for safe temporary withdrawal of dual oral antiplatelet therapy.
Topics: Administration, Oral; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Contraindications; Drug Therapy, Combination; Drug-Eluting Stents; Fibrinolytic Agents; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Preoperative Care; Surgical Procedures, Operative; Ticlopidine; Tirofiban; Tyrosine | 2008 |
Relation of low response to clopidogrel assessed with point-of-care assay to periprocedural myonecrosis in patients undergoing elective coronary stenting for stable angina pectoris.
Topics: Aged; Angina Pectoris; Aspirin; Clopidogrel; Confidence Intervals; Elective Surgical Procedures; Female; Follow-Up Studies; Humans; Incidence; Male; Myocardial Infarction; Myocardial Revascularization; Odds Ratio; Platelet Aggregation Inhibitors; Point-of-Care Systems; Preoperative Care; Prospective Studies; Risk Factors; Stents; Ticlopidine; Treatment Outcome; Troponin T | 2008 |
Current practice of antithrombotic treatment in ischemic stroke: a survey among Hungarian neurologists.
Topics: Adult; Aged; Anticoagulants; Aspirin; Brain Ischemia; Clopidogrel; Dipyridamole; Drug Prescriptions; Drug Therapy, Combination; Female; Fibrinolytic Agents; Health Care Surveys; Humans; Hungary; Male; Middle Aged; Neurology; Platelet Aggregation; Platelet Aggregation Inhibitors; Practice Patterns, Physicians'; Stroke; Surveys and Questionnaires; Ticlopidine | 2008 |
Safety and efficacy of clopidogrel in children with heart disease.
Topics: Adolescent; Aspirin; Child; Child, Preschool; Clopidogrel; Female; Heart Diseases; Hemorrhage; Humans; Infant; Infant, Newborn; Male; Platelet Aggregation Inhibitors; Retrospective Studies; Ticlopidine; Warfarin | 2008 |
Overview of advances in cardiovascular disease treatment and prevention: the evolving role of antiplatelet therapy.
Topics: Aged; Aspirin; Cardiovascular Diseases; Clinical Protocols; Clopidogrel; Drug Therapy; Female; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine; United States | 2008 |
The perioperative management of antithrombotic therapy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).
Topics: Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Evidence-Based Medicine; Fibrinolytic Agents; Heparin, Low-Molecular-Weight; Humans; Injections, Subcutaneous; Perioperative Care; Platelet Aggregation Inhibitors; Thrombolytic Therapy; Ticlopidine; Treatment Outcome; Vitamin K | 2008 |
Antithrombotic and thrombolytic therapy for ischemic stroke: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).
Topics: Aspirin; Brain Ischemia; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Evidence-Based Medicine; Fibrinolytic Agents; Heparin, Low-Molecular-Weight; Humans; Injections, Intravenous; Injections, Subcutaneous; Platelet Aggregation Inhibitors; Risk Assessment; Risk Factors; Stroke; Thrombolytic Therapy; Ticlopidine; Tissue Plasminogen Activator | 2008 |
Antithrombotic therapy for non-ST-segment elevation acute coronary syndromes: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Electrocardiography; Fibrinolytic Agents; Fondaparinux; Heparin, Low-Molecular-Weight; Humans; Platelet Aggregation Inhibitors; Polysaccharides; Risk Assessment; Risk Factors; Ticlopidine; Tirofiban; Tyrosine | 2008 |
The primary and secondary prevention of coronary artery disease: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).
Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Evidence-Based Medicine; Fibrinolytic Agents; Humans; Primary Prevention; Risk Assessment; Risk Factors; Ticlopidine | 2008 |
[ASS plus dipyridamole or clopidogrel after stroke: what is the best secondary prevention?].
Topics: Aspirin; Cerebral Infarction; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Germany; Humans; Multicenter Studies as Topic; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Secondary Prevention; Ticlopidine | 2008 |
Upper gastrointestinal bleeding in patients with aspirin and clopidogrel co-therapy.
Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Myocardial Ischemia; Odds Ratio; Platelet Aggregation Inhibitors; Ticlopidine | 2008 |
[Secondary stroke prevention according to the PRoFESS Study. What are the sequelae for practical therapy?].
Topics: Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Germany; Humans; Multicenter Studies as Topic; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Recurrence; Stroke; Ticlopidine | 2008 |
Very late stent thrombosis after drug-eluting stent implantation in a patient without aspirin and clopidogrel resistance.
Topics: Aged; Angina Pectoris; Aspirin; Clopidogrel; Coronary Angiography; Coronary Thrombosis; Drug Resistance; Drug-Eluting Stents; Electrocardiography; Female; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors | 2008 |
Effectiveness of antiplatelet drugs against experimental non-alcoholic fatty liver disease.
Topics: Alanine Transaminase; Animals; Aspirin; Cholesterol; Choline Deficiency; Cilostazol; Dietary Fats; Drug Evaluation, Preclinical; Fatty Liver; Humans; Liver Cirrhosis, Experimental; Male; Platelet Aggregation Inhibitors; Rats; Rats, Inbred F344; Tetrazoles; Ticlopidine; Treatment Outcome | 2008 |
Clopidogrel but not Aspirin prevents acute smoking-induced platelet aggregation in patients with stable coronary artery disease.
Topics: Adult; Aspirin; Clopidogrel; Coronary Artery Disease; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Smoking; Ticlopidine | 2009 |
Comparison of stent thrombosis, myocardial infarction, and mortality following drug-eluting versus bare-metal stent coronary intervention in patients with diabetes mellitus.
Topics: Aged; Aspirin; Clopidogrel; Denmark; Diabetes Complications; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Prospective Studies; Risk Factors; Stents; Thrombosis; Ticlopidine; Treatment Outcome | 2008 |
Benefit of clopidogrel for acute coronary syndrome and percutaneous coronary interventions in doubt due to rebound adverse events.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2008 |
Lack of early augmentation of platelet reactivity after coronary intervention in patients treated with bivalirudin.
Topics: Adenosine Diphosphate; Angina Pectoris; Anticoagulants; Aspirin; Cardiac Catheterization; Clopidogrel; Elective Surgical Procedures; Hemostatics; Hirudins; Humans; Peptide Fragments; Platelet Activation; Platelet Aggregation Inhibitors; Postoperative Period; Recombinant Proteins; Thrombin; Ticlopidine; Time Factors | 2009 |
Antiplatelet therapy in acute coronary syndromes.
Topics: Acute Coronary Syndrome; Adenosine; Adenosine Monophosphate; Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Piperazines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prasugrel Hydrochloride; Thiophenes; Ticagrelor; Ticlopidine | 2008 |
Baseline platelet activity and response after clopidogrel in 257 diabetics among 822 patients with coronary artery disease.
Topics: Aged; Aspirin; Baltimore; Biomarkers; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus; Female; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine; Treatment Outcome | 2008 |
Efficient tirofiban infusion resulting in resolution of intracoronary thrombus.
Topics: Anticholesteremic Agents; Aspirin; Atorvastatin; Clopidogrel; Coronary Angiography; Coronary Thrombosis; Drug Therapy, Combination; Electrocardiography; Fibrinolytic Agents; Heptanoic Acids; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Platelet Aggregation Inhibitors; Pyrroles; Ticlopidine; Tirofiban; Tyrosine | 2008 |
Effects of rosuvastatin on platelet inhibition by clopidogrel in cardiovascular patients.
Topics: Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Female; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Pyrimidines; Retrospective Studies; Rosuvastatin Calcium; Sulfonamides; Ticlopidine | 2009 |
Increased major bleeding complications related to triple antithrombotic therapy usage in patients with atrial fibrillation undergoing percutaneous coronary artery stenting.
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Drug Therapy, Combination; Female; Fibrinolytic Agents; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Retrospective Studies; Risk Factors; Stents; Ticlopidine; Warfarin | 2008 |
Arterial antithrombotic and bleeding time effects of apixaban, a direct factor Xa inhibitor, in combination with antiplatelet therapy in rabbits.
Topics: Animals; Aspirin; Bleeding Time; Carotid Artery Thrombosis; Clopidogrel; Drug Therapy, Combination; Factor Xa Inhibitors; Fibrinolytic Agents; Platelet Aggregation Inhibitors; Pyrazoles; Pyridones; Rabbits; Ticlopidine; Treatment Outcome | 2008 |
[Perioperative management of patients with drug-eluting coronary stents presenting for non-cardiac surgery].
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Cilostazol; Drug Administration Schedule; Drug-Eluting Stents; Female; Heparin; Humans; Male; Middle Aged; Perioperative Care; Platelet Aggregation Inhibitors; Tetrazoles; Thrombosis; Ticlopidine; Time Factors | 2008 |
Reversible clopidogrel resistance due to right ventricular myocardial infarction: risk factor of recurrent stent thrombosis?
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Stenosis; Coronary Thrombosis; Drug Resistance; Drug Therapy, Combination; Drug-Eluting Stents; Electrocardiography; Enoxaparin; Fibrinolytic Agents; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Recurrence; Risk Factors; Ticlopidine; Time Factors; Tirofiban; Treatment Outcome; Tyrosine; Ventricular Dysfunction, Right | 2008 |
Antiplatelet therapy for patients with stents.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stents; Thrombosis; Ticlopidine | 2008 |
Incidence and causes of new-onset dyspnea in 3,719 patients treated with clopidogrel and aspirin combination after coronary stenting.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Therapy, Combination; Dyspnea; Female; Follow-Up Studies; Humans; Incidence; Male; Middle Aged; Platelet Aggregation Inhibitors; Registries; Risk Factors; Stents; Surveys and Questionnaires; Thrombosis; Ticlopidine | 2008 |
Hydrolysis of adenine nucleotides in platelets from patients with acute myocardial infarction.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aspirin; Blood Platelets; Case-Control Studies; Clopidogrel; Female; Humans; Hydrolysis; Male; Middle Aged; Myocardial Infarction; Ticlopidine | 2008 |
Evaluation of triple anti-platelet therapy by modified thrombelastography in patients with acute coronary syndrome.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Thrombelastography; Ticlopidine; Tirofiban; Tyrosine | 2008 |
The PRoFESS trial results: what went wrong?
Topics: Aspirin; Clopidogrel; Dipyridamole; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stroke; Ticlopidine | 2008 |
CHARISMA revisited: is the glass half full or just empty?
Topics: Aspirin; Clopidogrel; Coronary Disease; Disease Progression; Humans; Platelet Aggregation Inhibitors; Primary Prevention; Randomized Controlled Trials as Topic; Registries; Stroke; Ticlopidine | 2008 |
Secondary stroke prevention with antiplatelet drugs: have we reached the ceiling?
Topics: Age Factors; Aged; Aspirin; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Middle Aged; Platelet Aggregation Inhibitors; Recurrence; Risk Assessment; Stroke; Ticlopidine; Time Factors | 2006 |
Post-PCI fatal bleeding in aspirin and clopidogrel hyper responder: shifting from antiplatelet resistance to bleeding risk assessment?
Topics: Acute Coronary Syndrome; Aspirin; Blood Platelets; Clopidogrel; Fatal Outcome; Female; Humans; Intracranial Hemorrhages; Middle Aged; Platelet Aggregation Inhibitors; Risk Assessment; Risk Factors; Ticlopidine | 2010 |
Aspirin resistance an underestimated risk in patients with drug-eluting stents?
Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Drug Resistance; Drug-Eluting Stents; Graft Occlusion, Vascular; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine | 2008 |
[Resistance to antiplatelet drugs in patients with non ST elevation acute coronary syndrome].
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Coronary Disease; Drug Resistance; Electrocardiography; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Severity of Illness Index; Syndrome; Ticlopidine; Treatment Outcome | 2008 |
Stroke prevention--insights from incoherence.
Topics: Angiotensin-Converting Enzyme Inhibitors; Aspirin; Benzimidazoles; Benzoates; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Risk; Secondary Prevention; Stroke; Telmisartan; Ticlopidine | 2008 |
Safety and efficacy of low-dose clopidogrel in Japanese patients undergoing coronary stenting: preliminary 30-day clinical outcome.
Topics: Aged; Aspirin; Clopidogrel; Coronary Disease; Coronary Restenosis; Coronary Thrombosis; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Safety; Stents; Ticlopidine; Treatment Outcome | 2008 |
Comment: Aspirin, clopidogrel, and warfarin: is the combination appropriate and effective or inappropriate and too dangerous?
Topics: Anticoagulants; Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine; Warfarin | 2008 |
[Secondary prevention with clopidogrel or acetylsalicylic acid after acute cerebrovascular event. Health services research study of private primary care specialists].
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Comorbidity; Cross-Sectional Studies; Female; Germany; Guideline Adherence; Humans; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Primary Health Care; Prospective Studies; Risk Factors; Secondary Prevention; Stroke; Ticlopidine; Treatment Outcome | 2008 |
Complications of needle electromyography: hematoma risk and correlation with anticoagulation and antiplatelet therapy.
Topics: Adult; Aged; Anticoagulants; Aspirin; Clopidogrel; Electrodes; Electrodiagnosis; Electromyography; Female; Hematoma; Humans; Incidence; Male; Middle Aged; Muscle, Skeletal; Needles; Patient Selection; Platelet Aggregation Inhibitors; Risk Assessment; Risk Factors; Ticlopidine; Ultrasonography | 2008 |
Utility of the PFA-100 instrument and the novel multiplate analyzer for the assessment of aspirin and clopidogrel effects on platelet function in patients with cardiovascular disease.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Clopidogrel; Collagen; Electric Impedance; Epinephrine; Female; Humans; Male; Middle Aged; Nephelometry and Turbidimetry; Platelet Activation; Platelet Function Tests; Sensitivity and Specificity; Ticlopidine | 2009 |
Management and outcome of peptic ulcers or erosions in patients receiving a combination of aspirin plus clopidogrel.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Coronary Disease; Female; Gastrointestinal Hemorrhage; Hemostasis, Endoscopic; Hospitalization; Humans; Male; Peptic Ulcer; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2008 |
[Inhibition of platelet aggregation and angiotensin II-receptor blockade following TIA; the unexpected results of the Prevention Regimen For Effectively Avoiding Second Strokes (PROFESS) trial].
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Aspirin; Benzimidazoles; Benzoates; Clopidogrel; Cost-Benefit Analysis; Dipyridamole; Headache; Humans; Platelet Aggregation Inhibitors; Stroke; Telmisartan; Ticlopidine | 2008 |
Anticoagulant and/or antiplatelet treatment in patients with atrial fibrillation after percutaneous coronary intervention. A single-center experience.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Atrial Fibrillation; Cardiovascular Diseases; Chi-Square Distribution; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Heparin, Low-Molecular-Weight; Humans; Incidence; Kaplan-Meier Estimate; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Risk; Stents; Ticlopidine; Time Factors; Treatment Outcome | 2008 |
[Severe myocardial infarction due to late and very late stent thrombosis after coronary artery stenting with drug-eluting stents].
Topics: Aged; Aspirin; Cardiac Catheterization; Clopidogrel; Coronary Angiography; Coronary Thrombosis; Creatine Kinase; Drug-Eluting Stents; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine | 2008 |
Dual antiplatelet therapy unmasks distinct platelet reactivity in patients with coronary artery disease.
Topics: Adenosine Diphosphate; Aged; Aspirin; Case-Control Studies; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Epinephrine; Female; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2008 |
Late outcomes after drug-eluting stent implantation in "real-world" clinical practice.
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Restenosis; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Registries; Ticlopidine; Time Factors; Treatment Outcome | 2008 |
Unprotected left main coronary artery bifurcation stenosis: impact of plaque debulking prior to single sirolimus-eluting stent implantation.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Vessels; Drug-Eluting Stents; Feasibility Studies; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Prospective Studies; Risk Factors; Sirolimus; Ticlopidine | 2008 |
Treatment of patients with cardiogenic shock in the setting of acute myocardial infarction. Case reports.
Topics: Aged; Angioplasty, Balloon; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carbazoles; Carvedilol; Clopidogrel; Combined Modality Therapy; Coronary Angiography; Drug Therapy, Combination; Electrocardiography; Female; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Propanolamines; Shock, Cardiogenic; Stents; Ticlopidine; Vasodilator Agents | 2008 |
Overcoming "resistance" to aspirin and clopidogrel with tirofiban: fact or fiction?
Topics: Aspirin; Clopidogrel; Coronary Thrombosis; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Tirofiban; Tyrosine | 2008 |
The impact of preinjury antiplatelet and anticoagulant pharmacotherapy on outcomes in elderly patients with hemorrhagic brain injury.
Topics: Age Factors; Aged; Anticoagulants; Aspirin; Brain Hemorrhage, Traumatic; Cardiovascular Diseases; Cause of Death; Clopidogrel; Cohort Studies; Comorbidity; Female; Follow-Up Studies; Geriatric Assessment; Hospital Mortality; Humans; Injury Severity Score; Male; Middle Aged; Platelet Aggregation Inhibitors; Preoperative Care; Retrospective Studies; Risk Assessment; Sex Factors; Survival Analysis; Ticlopidine; Trauma Centers; Treatment Outcome; Warfarin; Wounds, Nonpenetrating | 2008 |
Predictors of mortality in trauma patients with intracranial hemorrhage on preinjury aspirin or clopidogrel.
Topics: Administration, Oral; Age Factors; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Blood Coagulation Tests; Brain Injuries; Case-Control Studies; Cause of Death; Clopidogrel; Female; Geriatric Assessment; Glasgow Coma Scale; Hospital Mortality; Humans; Intracranial Hemorrhages; Male; Middle Aged; Multiple Trauma; Predictive Value of Tests; Probability; Prognosis; Reference Values; Retrospective Studies; Risk Assessment; Survival Analysis; Ticlopidine; Tomography, X-Ray Computed; Trauma Centers | 2008 |
[Thrombocyte aggregation inhibitor after surgery for an abdominal aortic aneurysm].
Topics: Aortic Aneurysm, Abdominal; Arteriosclerosis; Aspirin; Blood Vessel Prosthesis Implantation; Cardiovascular Diseases; Clopidogrel; Female; Humans; Male; Platelet Aggregation Inhibitors; Postoperative Care; Risk Factors; Thrombosis; Ticlopidine | 2008 |
Cardiovascular outcomes after a change in prescription policy for clopidogrel.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Bypass; Drug Therapy, Combination; Female; Health Policy; Hemorrhage; Humans; Insurance Benefits; Insurance, Health, Reimbursement; Insurance, Pharmaceutical Services; Male; Myocardial Infarction; National Health Programs; Ontario; Platelet Aggregation Inhibitors; Practice Patterns, Physicians'; Recurrence; Stents; Ticlopidine | 2008 |
Short- and long-term efficacy of aspirin and clopidogrel for thromboprophylaxis for mechanical heart valves: an in vivo study in swine.
Topics: Administration, Oral; Animals; Aspirin; Bioprosthesis; Clopidogrel; Dalteparin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Heart Valve Prosthesis Implantation; Injections, Subcutaneous; Postoperative Care; Postoperative Complications; Random Allocation; Risk Factors; Sensitivity and Specificity; Statistics, Nonparametric; Survival Rate; Swine; Thromboembolism; Thrombolytic Therapy; Ticlopidine; Time Factors | 2008 |
[Acute coronary syndrome -- long term protection by dual thrombocyte aggregation inhibition during twelve months].
Topics: Acute Coronary Syndrome; Angina, Unstable; Angioplasty, Balloon, Coronary; Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Artery Bypass; Diagnosis, Differential; Drug Therapy, Combination; Electrocardiography; Follow-Up Studies; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Secondary Prevention; Stents; Ticlopidine; Time Factors; Troponin | 2008 |
Adrenoreceptors, platelet reactivity and clopidogrel resistance.
Topics: Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Resistance; Drug Therapy, Combination; Humans; Norepinephrine; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Receptors, Adrenergic, alpha-2; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Ticlopidine; Treatment Failure | 2008 |
Pro: 'Antithrombotic therapy with warfarin, aspirin and clopidogrel is the recommended regime in anticoagulated patients who present with an acute coronary syndrome and/or undergo percutaneous coronary interventions'.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Drug Therapy, Combination; Fibrinolytic Agents; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Risk Assessment; Thrombosis; Ticlopidine; Warfarin | 2008 |
Contra: 'Antithrombotic therapy with warfarin, aspirin and clopidogrel is the recommended regimen in anticoagulated patients who present with an acute coronary syndrome and/or undergo percutaneous coronary interventions'. Not for everybody.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Drug Therapy, Combination; Fibrinolytic Agents; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Risk Assessment; Thrombosis; Ticlopidine; Warfarin | 2008 |
Analysis of platelet alpha2-adrenergic receptor activity in stable coronary artery disease patients on dual antiplatelet therapy.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adrenergic alpha-Antagonists; Aged; Aspirin; Blood Platelets; Clopidogrel; Collagen; Coronary Artery Disease; Drug Resistance; Drug Therapy, Combination; Female; Humans; Imidazoles; Male; Middle Aged; Norepinephrine; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Receptors, Adrenergic, alpha-2; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Ticlopidine; Treatment Failure | 2008 |
Measurement of the platelet retention rate in a column of collagen-coated beads is useful for the assessment of efficacy of antiplatelet therapy.
Topics: Aged; Aspirin; Blood Platelets; Cell Separation; Clopidogrel; Collagen; Coronary Artery Disease; Female; Humans; In Vitro Techniques; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine; Treatment Outcome | 2009 |
Association between the efficacy of dual antiplatelet therapy and the development of in-stent neointimal hyperplasia in porcine coronary arteries.
Topics: Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Animals; Aspirin; Cell Proliferation; Clopidogrel; Collagen; Coronary Angiography; Coronary Stenosis; Coronary Vessels; Cytokines; Disease Models, Animal; Drug Therapy, Combination; Fibrin; Hyperplasia; Inflammation Mediators; Metals; P-Selectin; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Prosthesis Design; Stents; Swine; Ticlopidine; Time Factors; Tunica Intima | 2008 |
[Perioperative discontinuation of antiplatelet therapy of patients with coronary stents. Reevaluating the risks].
Topics: Algorithms; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Restenosis; Decision Trees; Drug-Eluting Stents; Hemorrhage; Humans; Intraoperative Complications; Long-Term Care; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Risk Assessment; Risk Factors; Substance Withdrawal Syndrome; Ticlopidine | 2009 |
Colonic carcinoma unmasked by dual antiplatelet therapy.
Topics: Aspirin; Clopidogrel; Colonic Neoplasms; Female; Gastrointestinal Hemorrhage; Humans; Incidental Findings; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine | 2008 |
Clopidogrel under scrutiny.
Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Immunoglobulin Fab Fragments; Myocardial Infarction; Myocardial Ischemia; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Research Design; Risk Assessment; Stents; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2008 |
Comparison between ticlopidine and clopidogrel in patients undergoing primary stenting in acute myocardial infarction: results from the CADILLAC trial.
Topics: Abciximab; Aged; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clopidogrel; Coronary Angiography; Drug Therapy, Combination; Europe; Female; Hemorrhage; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Multicenter Studies as Topic; Myocardial Infarction; Myocardial Ischemia; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Assessment; Stents; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome; United States | 2008 |
ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use: a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Clopidogrel; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Helicobacter Infections; Helicobacter pylori; Humans; Platelet Aggregation Inhibitors; Risk Factors; Societies, Medical; Ticlopidine; United States | 2008 |
Measurement of antiplatelet inhibition during neurointerventional procedures: the effect of antithrombotic duration and loading dose.
Topics: Aspirin; Blood Platelets; Brain Diseases; Clopidogrel; Cohort Studies; Dose-Response Relationship, Drug; Female; Humans; Male; Platelet Aggregation Inhibitors; Prospective Studies; Stents; Ticlopidine; Time Factors | 2010 |
Point-of-care whole blood impedance aggregometry versus classical light transmission aggregometry for detecting aspirin and clopidogrel: the results of a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Coronary Artery Bypass; Female; Humans; Male; Middle Aged; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Point-of-Care Systems; ROC Curve; Ticlopidine | 2008 |
Antiplatelets for stroke prevention: implications of the PRoFESS trial.
Topics: Aspirin; Cerebral Hemorrhage; Clopidogrel; Delayed-Action Preparations; Dipyridamole; Drug Therapy, Combination; Heart Diseases; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stroke; Ticlopidine | 2009 |
ADP-induced platelet aggregation in acute ischemic stroke patients on aspirin therapy.
Topics: Acute Disease; Adenosine Diphosphate; Aged; Aspirin; Brain Ischemia; Clopidogrel; Drug Synergism; Drug Therapy, Combination; Endpoint Determination; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Secondary Prevention; Stroke; Ticlopidine; Treatment Outcome | 2008 |
Gemcitabine-induced acute coronary syndrome: a case report.
Topics: Antimetabolites, Antineoplastic; Aspirin; Bundle-Branch Block; Clopidogrel; Coronary Artery Disease; Coronary Vasospasm; Deoxycytidine; Electrocardiography; Fatal Outcome; Female; Gemcitabine; Humans; Leiomyosarcoma; Lung Neoplasms; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine | 2009 |
Long-term outcomes in patients undergoing coronary stenting on dual oral antiplatelet treatment requiring oral anticoagulant therapy.
Topics: Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Disease-Free Survival; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Humans; International Normalized Ratio; Male; Middle Aged; Mortality; Myocardial Infarction; Outcome Assessment, Health Care; Platelet Aggregation Inhibitors; Prospective Studies; Stents; Stroke; Ticlopidine | 2008 |
The effects of clopidogrel on elderly traumatic brain injured patients.
Topics: Aged; Aspirin; Brain Damage, Chronic; Brain Injuries; Cardiovascular Diseases; Case-Control Studies; Clopidogrel; Disability Evaluation; Female; Glasgow Coma Scale; Humans; Length of Stay; Male; Platelet Aggregation Inhibitors; Prognosis; Registries; Retrospective Studies; Ticlopidine; Warfarin | 2008 |
Use of aspirin versus clopidogrel plus aspirin after coronary artery bypass graft surgery.
Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Bypass; Drug Therapy, Combination; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Survivors; Ticlopidine | 2009 |
Efficacy and safety of optimized antithrombotic therapy with aspirin, clopidogrel and enoxaparin in patients with non-ST segment elevation acute coronary syndromes in clinical practice.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Drug Evaluation; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Enoxaparin; Female; Fibrinolytic Agents; Hemorrhage; Heparin; Hospital Mortality; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Registries; Retrospective Studies; Ticlopidine; Treatment Outcome | 2009 |
A cost-utility analysis of clopidogrel in patients with ST elevation acute coronary syndromes in the UK.
Topics: Aspirin; Clopidogrel; Cost-Benefit Analysis; Drug Costs; Follow-Up Studies; Humans; Markov Chains; Middle Aged; Models, Econometric; Myocardial Infarction; Platelet Aggregation Inhibitors; Quality-Adjusted Life Years; Survival Analysis; Ticlopidine; United Kingdom | 2010 |
Death caused by simultaneous subacute stent thrombosis of sirolimus-eluting stents in left anterior descending artery and left circumflex artery.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Clopidogrel; Coronary Angiography; Coronary Occlusion; Coronary Stenosis; Coronary Thrombosis; Drug-Eluting Stents; Electrocardiography; Fatal Outcome; Humans; Immunosuppressive Agents; Male; Middle Aged; Platelet Aggregation Inhibitors; Sirolimus; Tetrazoles; Ticlopidine; Ventricular Fibrillation | 2010 |
Relation of platelet aggregation and fibrinogen levels to advancing age in aspirin- and thienopyridine-treated patients.
Topics: Aged; Aging; Aspirin; Clopidogrel; Cohort Studies; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fibrinogen; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2008 |
Another view on prasugrel.
Topics: Administration, Oral; Angioplasty, Balloon, Coronary; Animals; Aspirin; Blood Platelets; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Drug Administration Schedule; Drug Resistance; Hemorrhage; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Research Design; Risk Assessment; Stents; Thiophenes; Ticlopidine; Treatment Outcome | 2009 |
Improving outcomes with antiplatelet therapies in percutaneous coronary intervention and stenting.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug-Eluting Stents; Hemorrhage; Humans; Patient Selection; Platelet Aggregation Inhibitors; Platelet Function Tests; Practice Guidelines as Topic; Prosthesis Design; Risk Assessment; Stents; Thrombelastography; Ticlopidine; Treatment Outcome | 2009 |
Bleeding risks with combination of oral anticoagulation plus antiplatelet therapy: is clopidogrel any safer than aspirin when combined with warfarin?
Topics: Administration, Oral; Anticoagulants; Aspirin; Blood Coagulation; Clopidogrel; Coumarins; Dipyridamole; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Hemorrhage; Hospitalization; Humans; Platelet Aggregation Inhibitors; Registries; Risk Assessment; Risk Factors; Ticlopidine; Warfarin | 2008 |
Predicting thrombotic events: creating a complex approach for a complex condition.
Topics: Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Arachidonic Acid; Aspirin; Clopidogrel; Collagen; Drug Resistance; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Predictive Value of Tests; Reproducibility of Results; Risk Assessment; Risk Factors; ROC Curve; Thrombosis; Ticlopidine | 2008 |
Effect of oral antiplatelet agents on major bleeding in users of coumarins.
Topics: Acenocoumarol; Administration, Oral; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Blood Coagulation; Case-Control Studies; Clopidogrel; Coumarins; Dipyridamole; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Hemorrhage; Hospitalization; Humans; Logistic Models; Male; Medical Records Systems, Computerized; Middle Aged; Netherlands; Odds Ratio; Phenprocoumon; Platelet Aggregation Inhibitors; Risk Assessment; Ticlopidine; Vitamin K | 2008 |
Ask the doctor. In October 2007, I had three Cypher stents placed in my left anterior descending artery. My doctor told me to take Plavix and aspirin indefinitely. Now I need to have a hernia repaired. My surgeon refuses to operate while I'm taking Plavix
Topics: Aspirin; Clopidogrel; Contraindications; Platelet Aggregation Inhibitors; Stents; Thoracic Surgery; Thrombophilia; Ticlopidine | 2008 |
The effect of antiplatelet drugs clopidogrel and aspirin is less immediately after stent implantation.
Topics: Aged; Angioplasty, Balloon, Coronary; Antiplatyhelmintic Agents; Aspirin; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Disease; Female; Heparin; Humans; In Vitro Techniques; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Platelet Aggregation; Platelet Function Tests; Stents; Ticlopidine; Time Factors; von Willebrand Factor | 2009 |
Utilization of evidence-based therapy for the secondary prevention of acute coronary syndromes in Australian practice.
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Clopidogrel; Cross-Sectional Studies; Drug Therapy, Combination; Evidence-Based Medicine; Female; Fibrinolytic Agents; Guideline Adherence; Humans; Male; Middle Aged; New South Wales; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Retrospective Studies; Sex Factors; Ticlopidine | 2008 |
Oral triple antiplatelet therapy after percutaneous coronary intervention: subject with ongoing arguments?
Topics: Administration, Oral; Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Clopidogrel; Coronary Restenosis; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stents; Tetrazoles; Ticlopidine; Treatment Outcome | 2010 |
[Recurrent idiopathic cerebral infarction in a 5-year-old boy, with emphasis on the importance of platelet aggregation analysis for appropriate selection of anti-platelet drugs].
Topics: Adenosine Diphosphate; Aspirin; Blood Coagulation Tests; Cerebral Infarction; Child, Preschool; Cilostazol; Collagen; Drug Therapy, Combination; Epinephrine; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Recurrence; Tetrazoles; Ticlopidine; Treatment Outcome | 2009 |
Safety issues of adjunctive clopidogrel in patients discharged after percutaneous coronary intervention with stent placement and requiring oral anticoagulation.
Topics: Administration, Oral; Adult; Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Female; Follow-Up Studies; Hemorrhage; Humans; Male; Middle Aged; Patient Discharge; Stents; Ticlopidine | 2011 |
Would self-expanding stent occlude middle cerebral artery perforators?
Topics: Adult; Aged; Angioplasty; Aspirin; Clopidogrel; Female; Follow-Up Studies; Humans; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Magnetic Resonance Imaging; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Stents; Stroke; Ticlopidine | 2009 |
Platelet function analysis: at the edge of meaning.
Topics: Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Cell Adhesion Molecules; Clopidogrel; Drug Resistance; Humans; Microfilament Proteins; Patient Selection; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Reproducibility of Results; Stents; Ticlopidine | 2009 |
Barriers to clopidogrel adherence following placement of drug-eluting stents.
Topics: Adult; Aspirin; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Drug-Eluting Stents; Exanthema; Female; Humans; Male; Medication Adherence; Platelet Aggregation Inhibitors; Ticlopidine | 2009 |
Prognosis of patients suffering an acute coronary syndrome while already under chronic clopidogrel therapy.
Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Disease-Free Survival; Drug Administration Schedule; Drug Therapy, Combination; Female; Hospital Mortality; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Proportional Hazards Models; Recurrence; Retrospective Studies; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome | 2009 |
Off-pump replacement of the INCOR implantable axial-flow pump.
Topics: Anticoagulants; Aspirin; Clopidogrel; Equipment Design; Heart-Assist Devices; Humans; Infusion Pumps, Implantable; International Normalized Ratio; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome; Ventricular Dysfunction, Left; Warfarin | 2009 |
Essential thrombocythemia: a case of acute ST-segment elevation myocardial infarction in a young female.
Topics: Adult; Age Factors; Antisickling Agents; Aspirin; Clopidogrel; Coronary Angiography; Female; Fibrinolytic Agents; Heparin; Humans; Hydroxyurea; Myocardial Infarction; Platelet Aggregation Inhibitors; Thrombocythemia, Essential; Ticlopidine; Tirofiban; Tissue Plasminogen Activator; Tyrosine | 2009 |
Drug-coated coronary stents offer life-saving benefits. A 74-year-old Ohio judge is still presiding in court three years after receiving the implants to reopen a blocked artery.
Topics: Aged; Aspirin; Clopidogrel; Contraindications; Coronary Disease; Drug-Eluting Stents; Humans; Male; Ohio; Platelet Aggregation Inhibitors; Retrospective Studies; Ticlopidine; Time Factors; Treatment Outcome | 2008 |
Knowledge of coronary stents, thrombosis and dual antiplatelet therapy among Spanish dentists.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Thrombosis; Coronary Vessels; Cross-Sectional Studies; Dentists; Health Knowledge, Attitudes, Practice; Humans; Platelet Aggregation Inhibitors; Spain; Stents; Surveys and Questionnaires; Ticlopidine | 2009 |
Antiplatelet effect of clopidogrel in patients with aspirin therapy undergoing percutaneous coronary interventions--limited inhibition of the P2Y12 receptor.
Topics: Adenosine Monophosphate; Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Ticlopidine; Treatment Outcome | 2009 |
Transient ischemic attack associated with stenosis of accessory middle cerebral artery: a case report.
Topics: Aphasia; Aspirin; Cerebral Angiography; Clopidogrel; Constriction, Pathologic; Humans; Hypertension; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Magnetic Resonance Angiography; Male; Middle Aged; Middle Cerebral Artery; Paresis; Platelet Aggregation Inhibitors; Ticlopidine | 2009 |
Facts and controversies of aspirin and clopidogrel therapy.
Topics: Acute Coronary Syndrome; Aspirin; Atherosclerosis; Blood Platelets; Brain Ischemia; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Myocardial Infarction; Piperazines; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Thiophenes; Ticlopidine | 2009 |
Evaluation of the platelet count drop method for assessment of platelet function in comparison with "gold standard" light transmission aggregometry.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Reproducibility of Results; Ticlopidine | 2009 |
[Bleeding or stent thrombosis in combination with drug-eluting stents].
Topics: Aneurysm, False; Aspirin; Blood Loss, Surgical; Clopidogrel; Coronary Artery Bypass; Drug-Eluting Stents; Fatal Outcome; Groin; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Risk Factors; Thrombosis; Ticlopidine | 2009 |
Focus on adjunctive pharmacotherapy to improve outcomes of percutaneous coronary intervention.
Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Chemotherapy, Adjuvant; Clopidogrel; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Therapy; Electrocardiography; Eptifibatide; Humans; Immunoglobulin Fab Fragments; Myocardial Infarction; Peptides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine; Treatment Outcome | 2009 |
Successful clopidogrel desensitization after drug-eluting stent implantation.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Desensitization, Immunologic; Drug-Eluting Stents; Electrocardiography; Exanthema; Humans; Male; Middle Aged; Myocardial Infarction; Paclitaxel; Platelet Aggregation Inhibitors; Pruritus; Ticlopidine | 2009 |
Long-term clopidogrel administration following severe coronary injury reduces proliferation and inflammation via inhibition of nuclear factor-kappaB and activator protein 1 activation in pigs.
Topics: Animals; Aspirin; Clopidogrel; Coronary Restenosis; Disease Models, Animal; Drug Therapy, Combination; NF-kappa B; Platelet Aggregation Inhibitors; Statistics as Topic; Sus scrofa; Ticlopidine; Time Factors; Transcription Factor AP-1 | 2009 |
Athero-embolic isolated splenic infarction following left cardiac catheterization.
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aortic Aneurysm, Abdominal; Aspirin; Atherosclerosis; Cardiac Catheterization; Clopidogrel; Coronary Stenosis; Embolism, Cholesterol; Heparin; Humans; Infarction; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Spleen; Thrombosis; Ticlopidine; Tomography, X-Ray Computed; Treatment Outcome; Warfarin | 2009 |
Variability of response to antiplatelet therapy: what should we do next?
Topics: Aspirin; Blood Platelets; Clinical Trials as Topic; Clopidogrel; Dose-Response Relationship, Drug; Drug Design; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2009 |
Relation of cytochrome P450 2C19 loss-of-function polymorphism to occurrence of drug-eluting coronary stent thrombosis.
Topics: Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Coronary Thrombosis; Cytochrome P-450 CYP2C19; Drug-Eluting Stents; Female; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Ticlopidine | 2009 |
Platelets play important roles in the late phase of the immediate hypersensitivity reaction.
Topics: Animals; Aspirin; Blood Platelets; Clopidogrel; Hypersensitivity, Immediate; Immunoglobulin E; Leukocytes; Mice; Ovalbumin; P-Selectin; Platelet Transfusion; Skin; Ticlopidine | 2009 |
Assessment of platelet inhibition secondary to clopidogrel and aspirin therapy in preoperative acute surgical patients measured by Thrombelastography Platelet Mapping.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Preoperative Care; Prospective Studies; Thrombelastography; Ticlopidine | 2009 |
Factors associated with aspirin resistance in patients premedicated with aspirin and clopidogrel for endovascular neurosurgery.
Topics: Aged; Aneurysm; Aspirin; Cerebral Revascularization; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Ticlopidine | 2009 |
Summaries for patients. What aspirin dose is safest and most effective for preventing heart disease?
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Primary Prevention; Risk Factors; Thrombosis; Ticlopidine | 2009 |
Summaries for patients. Aspirin for the prevention of cardiovascular disease: U.S. Preventive Services Task Force recommendation statement.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Primary Prevention; Risk Factors; Thrombosis; Ticlopidine | 2009 |
Aspirin to prevent cardiovascular disease: the association of aspirin dose and clopidogrel with thrombosis and bleeding.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Observation; Platelet Aggregation Inhibitors; Primary Prevention; Prospective Studies; Randomized Controlled Trials as Topic; Risk Factors; Thrombosis; Ticlopidine | 2009 |
Does the combination of warfarin and aspirin have a place in secondary stroke prevention? Yes.
Topics: Anticoagulants; Aspirin; Clopidogrel; Delayed-Action Preparations; Dipyridamole; Drug Therapy, Combination; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Risk; Stroke; Ticlopidine; Warfarin | 2009 |
Prolonged dual antiplatelet therapy improves clinical outcomes in high-risk patients implanted with sirolimus-eluting stents.
Topics: Aspirin; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Female; Graft Occlusion, Vascular; Humans; Immunosuppressive Agents; Male; Platelet Aggregation Inhibitors; Retrospective Studies; Sirolimus; Ticlopidine; Treatment Outcome | 2009 |
PCI, stents, clopidogrel and non-cardiac surgery.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Stents; Surgical Procedures, Operative; Ticlopidine | 2009 |
Clopidogrel for preventing cardiovascular events.
Topics: Aspirin; Clopidogrel; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Evidence-Based Medicine; Female; Humans; Hypertension; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Prognosis; Stroke; Ticlopidine | 2009 |
Platelet activity and outcome after intracerebral hemorrhage.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Platelets; Cerebral Hemorrhage; Clopidogrel; Female; Glasgow Coma Scale; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Severity of Illness Index; Ticlopidine; Treatment Outcome | 2009 |
Very late drug-eluting stent thrombosis after nonsteroidal anti-inflammatory drug treatment despite dual antiplatelet therapy.
Topics: Adult; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Thrombosis; Cyclooxygenase Inhibitors; Diabetic Angiopathies; Diclofenac; Drug Interactions; Drug-Eluting Stents; Endothelium, Vascular; Humans; Intervertebral Disc Displacement; Male; Meloxicam; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation Inhibitors; Thiazines; Thiazoles; Ticlopidine; Time Factors | 2009 |
Does the Holy Grail escape us again?
Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2009 |
Treatment of multilesion coronary artery disease with simultaneous drug-eluting and bare-metal stent implantation: clinical follow up and angiographic mid-term results.
Topics: Abciximab; Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; Coronary Vessels; Databases as Topic; Drug-Eluting Stents; Drug-Related Side Effects and Adverse Reactions; Female; Heparin; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Stents; Ticlopidine; Time Factors; Treatment Outcome | 2009 |
Combined, superselective pharmacological management of large coronary thrombus burden.
Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Aspirin; Clopidogrel; Coronary Thrombosis; Humans; Immunoglobulin Fab Fragments; Platelet Aggregation Inhibitors; Registries; Stents; Ticlopidine; Urokinase-Type Plasminogen Activator | 2009 |
Spontaneous coronary artery dissection and severe hypothyroidism.
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Vessels; Eptifibatide; Fatal Outcome; Female; Humans; Hypothyroidism; Neck Pain; Peptides; Platelet Aggregation Inhibitors; Ticlopidine | 2009 |
Bridging with GP IIb/IIIa inhibitors after abdominal surgery in a patient presenting with late stent thrombosis of a drug-eluting stent and who cannot receive oral antiplatelet treatment.
Topics: Administration, Oral; Aged; Aspirin; Clopidogrel; Coronary Restenosis; Coronary Thrombosis; Drug-Eluting Stents; Humans; Male; Perioperative Care; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoprotein IIb; Ticlopidine; Time Factors | 2009 |
Clopidogrel and proton pump inhibitors: gastric protection at expense of vascular benefit?
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Drug Interactions; Drug Therapy, Combination; Humans; Omeprazole; Pantoprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Proton Pump Inhibitors; Stents; Ticlopidine | 2009 |
Impact of proton pump inhibitors on the antiplatelet effects of clopidogrel.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Cross-Sectional Studies; Drug Interactions; Drug Therapy, Combination; Esomeprazole; Female; Humans; Male; Middle Aged; Multivariate Analysis; Omeprazole; Pantoprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Proton Pump Inhibitors; Stents; Ticlopidine | 2009 |
Dual antiplatelet drug resistance is a risk factor for cardiovascular events after percutaneous coronary intervention.
Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Drug Resistance; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine | 2009 |
Assessment of sirolimus-eluting coronary stent implantation with aspirin plus low dose ticlopidine administration: one year results from CYPHER Stent Japan Post-Marketing Surveillance Registry (J-PMS).
Topics: Aged; Aspirin; Combined Modality Therapy; Coronary Angiography; Coronary Thrombosis; Coronary Vessels; Dose-Response Relationship, Drug; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Platelet Aggregation Inhibitors; Product Surveillance, Postmarketing; Registries; Sirolimus; Ticlopidine; Treatment Outcome; Ultrasonography, Interventional | 2009 |
Proton pump inhibitors and clopidogrel - hazardous drug interaction or hazardous interpretation of data?
Topics: Aspirin; Clopidogrel; Cytochrome P-450 Enzyme System; Data Interpretation, Statistical; Drug Interactions; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Randomized Controlled Trials as Topic; Risk Assessment; Ticlopidine | 2009 |
[Do antiplatelet agents (aspirin and other antiplatelets such as clopidogrel) increase the risk of hemorrhagic complications after endoscopic polypectomy or endoscopic sphincterotomy and should these drugs therefore be withdrawn 7-10 days before these pro
Topics: Aspirin; Clopidogrel; Colonic Polyps; Colonoscopy; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Postoperative Complications; Practice Guidelines as Topic; Preoperative Care; Risk Factors; Sphincterotomy, Endoscopic; Ticlopidine; Time Factors | 2009 |
Incidence of stent thrombosis in patients with drug eluting stents and short-term dual antiplatelet therapy.
Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Agents; Clopidogrel; Coronary Artery Disease; Databases as Topic; Drug Administration Schedule; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Incidence; Kaplan-Meier Estimate; Male; Medication Adherence; Middle Aged; Paclitaxel; Platelet Aggregation Inhibitors; Sirolimus; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2009 |
Reduced platelet activity is more common than reported anti-platelet medication use in patients with intracerebral hemorrhage.
Topics: Aged; Aspirin; Blood Platelets; Cerebral Hemorrhage; Clopidogrel; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Risk Factors; Ticlopidine; Warfarin | 2009 |
Dual antiplatelet therapy after percutaneous coronary intervention with stent implantation in patients taking chronic oral anticoagulation.
Topics: Administration, Oral; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Restenosis; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Postoperative Complications; Retrospective Studies; Stents; Ticlopidine; Time Factors; Treatment Outcome | 2008 |
Incidence and prognostic significance of thrombocytopenia developed during acute coronary syndrome in contemporary clinical practice.
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Angina, Unstable; Anticoagulants; Aspirin; Clopidogrel; Female; Hemorrhage; Heparin; Humans; Incidence; Inpatients; Logistic Models; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Platelet Count; Prognosis; Registries; Risk Factors; Severity of Illness Index; Thrombocytopenia; Ticlopidine | 2009 |
Aspirin plus clopidogrel and risk of infection after coronary artery bypass surgery.
Topics: Aged; Aspirin; Bacteremia; Blood Transfusion; Clopidogrel; Cohort Studies; Coronary Artery Bypass; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Surgical Wound Infection; Ticlopidine; Transfusion Reaction | 2009 |
Effective platelet inhibition by aspirin and clopidogrel: where are we now?
Topics: Aspirin; Clopidogrel; Coronary Disease; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk Factors; Secondary Prevention; Ticlopidine; Treatment Failure | 2009 |
Influence of platelet reactivity and response to clopidogrel on myocardial damage following percutaneous coronary intervention in patients with non-ST-segment elevation acute coronary syndrome.
Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Clopidogrel; Female; Heart; Humans; Male; Middle Aged; Myocardium; Platelet Aggregation; Prospective Studies; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Ticlopidine | 2009 |
Combined carotid stenting and urgent coronary artery surgery in unstable angina patients with severe carotid stenosis.
Topics: Aged; Aged, 80 and over; Angina, Unstable; Angioplasty, Balloon; Anticoagulants; Aspirin; Carotid Stenosis; Clopidogrel; Coronary Artery Bypass; Coronary Artery Bypass, Off-Pump; Coronary Artery Disease; Drug Administration Schedule; Female; Heparin; Humans; Male; Platelet Aggregation Inhibitors; Risk Assessment; Severity of Illness Index; Stents; Ticlopidine; Time Factors; Treatment Outcome | 2009 |
[Introduction to the topic: drug eluting stents. An underestimated problem in surgery].
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Restenosis; Drug-Eluting Stents; Hemorrhage; Humans; Intraoperative Complications; Long-Term Care; Platelet Aggregation Inhibitors; Risk Factors; Substance Withdrawal Syndrome; Ticlopidine | 2009 |
[Patients with coronary artery stents: when and how should operations be carried out?].
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Cooperative Behavior; Coronary Restenosis; Drug Therapy, Combination; Drug-Eluting Stents; Hemorrhage; Humans; Interdisciplinary Communication; Intraoperative Complications; Long-Term Care; Patient Education as Topic; Platelet Aggregation Inhibitors; Reoperation; Risk Factors; Substance Withdrawal Syndrome; Ticlopidine | 2009 |
[Drug-eluting stents: implications for surgery patients].
Topics: Algorithms; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Cooperative Behavior; Coronary Restenosis; Decision Trees; Drug-Eluting Stents; Evidence-Based Medicine; Guideline Adherence; Hemorrhage; Humans; Interdisciplinary Communication; Intraoperative Complications; Long-Term Care; Patient Care Team; Platelet Aggregation Inhibitors; Risk Assessment; Substance Withdrawal Syndrome; Ticlopidine | 2009 |
Effect of exercise on platelet activation during aspirin or clopidogrel intake in healthy men.
Topics: Adolescent; Adult; Aspirin; Clopidogrel; Exercise; Humans; In Vitro Techniques; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Ticlopidine; von Willebrand Factor; Young Adult | 2009 |
The ACTIVE pursuit of stroke prevention in patients with atrial fibrillation.
Topics: Aspirin; Atrial Fibrillation; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Vitamin K | 2009 |
Measurement of platelet P-selectin for remote testing of platelet function during treatment with clopidogrel and/or aspirin.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Aspirin; Cardiovascular Diseases; Case-Control Studies; Clopidogrel; Drug Monitoring; Female; Flow Cytometry; Humans; Male; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine; Tissue Fixation | 2009 |
Evidence guided antiplatelet treatment: time to move from bench to bedside.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiology; Cardiovascular Diseases; Clopidogrel; Drug Therapy; Evidence-Based Medicine; Humans; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine | 2009 |
Platelet reactivity on aspirin, clopidogrel and abciximab in patients with acute coronary syndromes and reduced estimated glomerular filtration rate.
Topics: Abciximab; Acute Coronary Syndrome; Aged; Aged, 80 and over; Antibodies, Monoclonal; Aspirin; Blood Platelets; Clopidogrel; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Ticlopidine | 2010 |
ACTIVE A: balancing the benefits and risks of clopidogrel and aspirin.
Topics: Aged; Aspirin; Atrial Fibrillation; Clopidogrel; Drug Therapy, Combination; Female; Humans; Intracranial Hemorrhages; Male; Platelet Aggregation Inhibitors; Risk; Stroke; Ticlopidine | 2009 |
An assessment of cardiopulmonary bypass-induced changes in platelet function using whole blood and classical light transmission aggregometry: the results of a pilot study.
Topics: Aged; Anesthesia; Aspirin; Blood Loss, Surgical; Blood Platelets; Cardiopulmonary Bypass; Clopidogrel; Female; Humans; Male; Middle Aged; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; ROC Curve; Ticlopidine | 2009 |
Acknowledging a failed strategy.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Disease-Free Survival; Drug Administration Schedule; Drug Therapy, Combination; Hospital Mortality; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Recurrence; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Treatment Failure; Treatment Outcome | 2009 |
A very late stent thrombosis in a patient with diabetes: a call for lifelong dual anti-platelet therapy.
Topics: Aspirin; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Follow-Up Studies; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Stents; Thrombosis; Ticlopidine; Time Factors | 2009 |
Clopidogrel. Patients with peptic ulcers.
Topics: Aspirin; Clopidogrel; Histamine H2 Antagonists; Humans; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Recurrence; Ticlopidine | 2009 |
Preliminary results of the hydroxyapatite nonpolymer-based sirolimus-eluting stent for the treatment of single de novo coronary lesions a first-in-human analysis of a third-generation drug-eluting stent system.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Agents; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; Coronary Thrombosis; Drug-Eluting Stents; Durapatite; Female; Humans; Male; Middle Aged; Pilot Projects; Platelet Aggregation Inhibitors; Prosthesis Design; Registries; Sirolimus; Stainless Steel; Ticlopidine; Time Factors; Treatment Outcome; Ultrasonography, Interventional | 2008 |
Lowering the dose of sirolimus, released from a nonpolymeric hydroxyapatite coated coronary stent, reduces signs of delayed healing.
Topics: Angioplasty, Balloon, Coronary; Animals; Aspirin; Cardiovascular Agents; Clopidogrel; Coated Materials, Biocompatible; Coronary Angiography; Coronary Restenosis; Coronary Vessels; Drug-Eluting Stents; Durapatite; Hyperplasia; Lipids; Materials Testing; Models, Animal; Platelet Aggregation Inhibitors; Prosthesis Design; Sirolimus; Stainless Steel; Surface Properties; Sus scrofa; Ticlopidine; Wound Healing | 2009 |
The excel stent: a good DES, but can we really stop clopidogrel after 6 months?
Topics: Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Agents; Clopidogrel; Coated Materials, Biocompatible; Coronary Artery Disease; Coronary Restenosis; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Platelet Aggregation Inhibitors; Polymers; Prosthesis Design; Risk Assessment; Sirolimus; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2009 |
1-year results of the hydroxyapatite polymer-free sirolimus-eluting stent for the treatment of single de novo coronary lesions: the VESTASYNC I trial.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease; Coronary Restenosis; Drug-Eluting Stents; Durapatite; Female; Humans; Intensive Care Units; Male; Middle Aged; Platelet Aggregation Inhibitors; Polymers; Prospective Studies; Sirolimus; Ticlopidine; Time Factors; Ultrasonography | 2009 |
A volumetric intravascular ultrasound comparison of early drug-eluting stent thrombosis versus restenosis.
Topics: Analysis of Variance; Aspirin; Clopidogrel; Coronary Restenosis; Coronary Thrombosis; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Retrospective Studies; Risk Factors; Ticlopidine; Time Factors; Ultrasonography, Interventional | 2009 |
Heterogeneous arterial healing in patients following paclitaxel-eluting stent implantation: comparison with sirolimus-eluting stents.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Aspirin; Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; Coronary Vessels; Drug-Eluting Stents; Endothelium, Vascular; Female; Humans; Male; Middle Aged; Paclitaxel; Platelet Aggregation Inhibitors; Retrospective Studies; Ticlopidine | 2009 |
Local determinants of thrombus formation following sirolimus-eluting stent implantation assessed by optical coherence tomography.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Restenosis; Coronary Thrombosis; Drug-Eluting Stents; Female; Humans; Immunosuppressive Agents; Japan; Male; Multivariate Analysis; Platelet Aggregation Inhibitors; Prospective Studies; Risk Assessment; Risk Factors; Sirolimus; Ticlopidine; Tomography, Optical Coherence; Ultrasonography, Interventional | 2009 |
Retinal artery embolization during carotid angioplasty and carotid artery stenting: case report.
Topics: Aged; Angioplasty, Balloon; Anticoagulants; Antipyrine; Aspirin; Carotid Artery, External; Carotid Stenosis; Cerebral Infarction; Combined Modality Therapy; Drug Therapy, Combination; Edaravone; Embolism; Heparin; Humans; Hyperbaric Oxygenation; Intraoperative Complications; Male; Methacrylates; Ophthalmic Artery; Recurrence; Retinal Artery Occlusion; Stents; Ticlopidine | 2009 |
Coronary artery disease: Platelet activity: an obstacle for successful PCI.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Humans; Patient Selection; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Risk Assessment; Risk Factors; Stents; Thrombosis; Ticlopidine; Treatment Outcome | 2009 |
Combined anti-platelet therapy with aspirin and clopidogrel: risk factor for thrombolysis-related intracerebral hemorrhage in acute ischemic stroke?
Topics: Aged; Aged, 80 and over; Aspirin; Brain Ischemia; Cerebral Hemorrhage; Clopidogrel; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Recombinant Proteins; Retrospective Studies; Risk Factors; Severity of Illness Index; Thrombolytic Therapy; Thrombophilia; Ticlopidine; Tissue Plasminogen Activator | 2009 |
Aprotinin reduces the antiplatelet effect of clopidogrel.
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Aged; Aprotinin; Aspirin; Clopidogrel; Coronary Artery Bypass; Drug Interactions; Drug Therapy, Combination; Female; Hemostatics; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2009 |
Prevention of stroke in patients with atrial fibrillation.
Topics: Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Drug Therapy, Combination; Humans; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Stroke; Ticlopidine; Treatment Outcome; Vitamin K; Warfarin | 2009 |
Prasugrel STEMI subgroup analysis.
Topics: Aspirin; Clopidogrel; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Myocardial Infarction; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Research Design; Thiophenes; Ticlopidine | 2009 |
Variability in aggregometry response before and after initiation of clopidogrel therapy.
Topics: Adenosine Diphosphate; Arachidonic Acid; Aspirin; Case-Control Studies; Clopidogrel; Demography; Female; Humans; Male; Middle Aged; Peptide Fragments; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Reproducibility of Results; Ticlopidine | 2009 |
Risks of proton-pump inhibitors: what every doctor should know. Comment.
Topics: Aspirin; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Gastric Acid; Gastric Mucosa; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Risk Factors; Secondary Prevention; Ticlopidine | 2009 |
Can we override clopidogrel resistance?
Topics: Aged; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Aspirin; Biotransformation; Clopidogrel; Combined Modality Therapy; Coronary Restenosis; Drug Resistance; Genotype; Humans; Male; Middle Aged; Myocardial Infarction; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Prasugrel Hydrochloride; Prodrugs; Radiography; Stents; Thiophenes; Ticlopidine | 2009 |
Cost-effectiveness of clopidogrel plus aspirin versus aspirin alone for secondary prevention of cardiovascular events: results from the CHARISMA trial.
Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Cost-Benefit Analysis; Databases, Factual; Drug Therapy, Combination; Female; Health Care Costs; Hospitalization; Humans; Life Expectancy; Male; Middle Aged; Multicenter Studies as Topic; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Saskatchewan; Secondary Prevention; Survival Analysis; Ticlopidine; United States | 2009 |
Frequency and outcomes of provisional glycoprotein IIb/IIIa blockade in patients receiving bivalirudin during percutaneous coronary intervention.
Topics: Abciximab; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Aspirin; Clopidogrel; Drug Therapy, Combination; Embolism; Eptifibatide; Female; Follow-Up Studies; Hirudins; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Peptide Fragments; Peptides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Recombinant Proteins; Registries; Regression Analysis; Retrospective Studies; Thrombosis; Ticlopidine; Treatment Outcome | 2009 |
Development and validation of a risk scoring model to predict net adverse cardiovascular outcomes after primary percutaneous coronary intervention in patients pretreated with 600 mg clopidogrel: rationale and design of the RISK-PCI study.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Female; Humans; Kaplan-Meier Estimate; Logistic Models; Longitudinal Studies; Male; Middle Aged; Models, Statistical; Models, Theoretical; Multivariate Analysis; Platelet Aggregation Inhibitors; Research Design; Risk Assessment; Risk Factors; ROC Curve; Ticlopidine; Treatment Outcome | 2009 |
Sirolimus and everolimus induce endothelial cellular senescence via sirtuin 1 down-regulation: therapeutic implication of cilostazol after drug-eluting stent implantation.
Topics: Aspirin; Cellular Senescence; Cilostazol; Clopidogrel; Down-Regulation; Drug-Eluting Stents; Endothelium, Vascular; Everolimus; Humans; Immunosuppressive Agents; Nitric Oxide Synthase Type III; Oxidative Stress; Paclitaxel; Plasminogen Activator Inhibitor 1; Platelet Aggregation Inhibitors; Sirolimus; Sirtuin 1; Sirtuins; Tetrazoles; Ticlopidine; Vasodilator Agents | 2009 |
Tailored medical and interventional therapy against recurrent stent thrombosis after drug-eluting stenting.
Topics: Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Thrombosis; Drug-Eluting Stents; Humans; Male; Middle Aged; Myocardial Infarction; Paclitaxel; Ticlopidine | 2010 |
Triple versus dual antiplatelet therapy in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Clopidogrel; Combined Modality Therapy; Coronary Thrombosis; Drug Therapy, Combination; Drug-Eluting Stents; Electrocardiography; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Proportional Hazards Models; Registries; Retrospective Studies; Tetrazoles; Ticlopidine | 2009 |
ACC/AHA guideline update for the management of ST-segment elevation myocardial infarction.
Topics: Antihypertensive Agents; Aspirin; Catheter Ablation; Clopidogrel; Combined Modality Therapy; Electrocardiography; Exercise Therapy; Humans; Hypolipidemic Agents; Myocardial Infarction; Myocardial Reperfusion; Platelet Aggregation Inhibitors; Secondary Prevention; Smoking Cessation; Ticlopidine | 2009 |
Clopidogrel versus low-dose aspirin as risk factors for epistaxis.
Topics: Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Epistaxis; Humans; Hypertension; Myocardial Ischemia; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine | 2009 |
[Percutaneous endoscopic gastrostomy. Complications with and without anticoagulation].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Child; Child, Preschool; Clopidogrel; Contraindications; Drug Therapy, Combination; Female; Gastrostomy; Heparin, Low-Molecular-Weight; Humans; Infant; Male; Middle Aged; Multivariate Analysis; Peritonitis; Pilot Projects; Postoperative Complications; Postoperative Hemorrhage; Prognosis; Prospective Studies; Risk Factors; Surgical Wound Infection; Thromboembolism; Ticlopidine | 2010 |
Dual antiplatelet therapy for more than 12 months after percutaneous coronary intervention: insights from the Guthrie PCI Registry.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Drug-Eluting Stents; Epidemiologic Methods; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2009 |
Prevalence and characteristics of traumatic intracranial hemorrhage in elderly fallers presenting to the emergency department without focal findings.
Topics: Accidental Falls; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Chi-Square Distribution; Clopidogrel; Emergency Service, Hospital; Female; Humans; Intracranial Hemorrhage, Traumatic; Logistic Models; Male; Prevalence; Retrospective Studies; Risk Factors; Ticlopidine; Tomography, X-Ray Computed; Warfarin | 2009 |
Invited commentary.
Topics: Aspirin; Clopidogrel; Coronary Artery Bypass; Female; Graft Occlusion, Vascular; Graft Survival; Humans; Male; Platelet Aggregation Inhibitors; Sensitivity and Specificity; Ticlopidine; Vascular Patency | 2009 |
The in-vitro effects of E5555, a protease-activated receptor (PAR)-1 antagonist, on platelet biomarkers in healthy volunteers and patients with coronary artery disease.
Topics: Aged; Aspirin; Biomarkers; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Synergism; Female; Flow Cytometry; Humans; Imines; In Vitro Techniques; Male; Middle Aged; Platelet Aggregation Inhibitors; Pyridines; Receptor, PAR-1; Thrombosis; Ticlopidine | 2009 |
[Pharmazie in unserer Zeit 4/2009].
Topics: Aspirin; Atherosclerosis; Clopidogrel; Drug Resistance; Humans; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Thiophenes; Ticlopidine | 2009 |
Aspirin for heart attack, stroke prevention. When benefits outweigh risks: four new studies help clarify who should--and who shouldn't--take the drug.
Topics: Aspirin; Clopidogrel; Contraindications; Drug Interactions; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stroke; Ticlopidine | 2009 |
Gastroprotective strategy in aspirin users.
Topics: Aspirin; Clopidogrel; Gastrointestinal Hemorrhage; Helicobacter Infections; Helicobacter pylori; Humans; Peptic Ulcer; Proton Pump Inhibitors; Ticlopidine | 2009 |
Obesity and cardiovascular thrombotic events in patients undergoing percutaneous coronary intervention with drug-eluting stents.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Blood Vessel Prosthesis; Body Mass Index; Clopidogrel; Coronary Disease; Death, Sudden, Cardiac; Drug-Eluting Stents; Female; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Obesity; Platelet Aggregation Inhibitors; Retrospective Studies; Thrombosis; Ticlopidine | 2009 |
Premature preoperative discontinuation of antiplatelet drug therapy in cardiovascular risk patients: a preliminary study on the role of P2Y12 receptor monitoring.
Topics: Adult; Aged; Aspirin; Blood Loss, Surgical; Cardiovascular Diseases; Case-Control Studies; Cell Adhesion Molecules; Clopidogrel; Female; Humans; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Phosphorylation; Platelet Aggregation Inhibitors; Platelet Function Tests; Preoperative Care; Prospective Studies; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Ticlopidine; Time Factors | 2010 |
Co-prescription of gastro-protectants in hospitalized patients: an analysis of what we do and what we think we do.
Topics: Aged; Aged, 80 and over; Aspirin; Attitude of Health Personnel; Clopidogrel; Data Collection; Female; Gastrointestinal Hemorrhage; Hospitals, Teaching; Humans; Male; Middle Aged; Peptic Ulcer; Platelet Aggregation Inhibitors; Practice Patterns, Physicians'; Proton Pump Inhibitors; Risk Factors; Ticlopidine | 2010 |
The formation of monocyte-platelet aggregates is independent of on-treatment residual agonists'-inducible platelet reactivity.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Angioplasty, Balloon; Angioplasty, Balloon, Coronary; Arachidonic Acid; Aspirin; Case-Control Studies; Cell Adhesion Molecules; Clopidogrel; Drug Therapy, Combination; Female; Flow Cytometry; Humans; Lipopolysaccharide Receptors; Male; Microfilament Proteins; Middle Aged; Monocytes; P-Selectin; Phosphoproteins; Phosphorylation; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIb-IX Complex; Stents; Ticlopidine | 2009 |
[Renal hypertension. A case report - therapeutic dilemmas].
Topics: Adult; Angiography; Angioplasty, Balloon; Aspirin; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Humans; Hypertension, Renal; Kidney; Male; Platelet Aggregation Inhibitors; Renal Artery Obstruction; Ticlopidine; Ultrasonography | 2009 |
Smoking promotes clopidogrel-mediated platelet inhibition in patients receiving dual antiplatelet therapy.
Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Retrospective Studies; Smoking; Ticlopidine | 2009 |
Spontaneous spinal epidural hematoma: an urgent complication of adding clopidogrel to aspirin therapy.
Topics: Aspirin; Clopidogrel; Coronary Stenosis; Decompression, Surgical; Drug Interactions; Hematoma, Epidural, Spinal; Humans; Hypertension; Magnetic Resonance Imaging; Male; Middle Aged; Platelet Aggregation Inhibitors; Spinal Cord; Stents; Ticlopidine; Treatment Outcome | 2009 |
Clopidogrel in ESRD patients with acute coronary syndrome.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Hemorrhage; Humans; Kidney Failure, Chronic; Platelet Aggregation Inhibitors; Ticlopidine | 2009 |
[ASS plus clopidogrel in contraindication for marcumar].
Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Contraindications; Drug Therapy, Combination; Humans; Intracranial Embolism; Phenprocoumon; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine | 2009 |
[Platelet inhibition remains the second choice. "Anticoagulation should always be the goal" (interview by Dr. med. Jochen Aumiller)].
Topics: Aged; Anticoagulants; Aspirin; Clopidogrel; Contraindications; Drug Therapy, Combination; Humans; Intracranial Embolism; Phenprocoumon; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine | 2009 |
Prevalence of aspirin and clopidogrel resistance among patients with and without drug-eluting stent thrombosis.
Topics: Aged; Aspirin; Case-Control Studies; Clopidogrel; Cohort Studies; Coronary Thrombosis; Drug Resistance; Drug-Eluting Stents; Female; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prevalence; Ticlopidine | 2009 |
Prevalence and risk factors for aspirin and clopidogrel resistance in patients with coronary artery disease or ischemic cerebrovascular disease.
Topics: Aged; Aspirin; Blood Pressure; Cerebral Arterial Diseases; Clopidogrel; Coronary Artery Disease; Drug Resistance; Female; Hemoglobins; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prevalence; Risk Factors; Ticlopidine | 2009 |
Fibrin clot inhibitor medication and efficacy of bacillus Calmette-Guerin for bladder urothelial cancer.
Topics: Adjuvants, Immunologic; Aged; Anticoagulants; Aspirin; BCG Vaccine; Carcinoma, Transitional Cell; Clopidogrel; Drug Interactions; Female; Fibrinolytic Agents; Humans; Male; Platelet Aggregation Inhibitors; Retrospective Studies; Ticlopidine; Urinary Bladder Neoplasms; Warfarin | 2009 |
Editorial comment.
Topics: Adjuvants, Immunologic; Anticoagulants; Aspirin; BCG Vaccine; Carcinoma, Transitional Cell; Clopidogrel; Drug Interactions; Female; Fibrinolytic Agents; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine; Urinary Bladder Neoplasms; Warfarin | 2009 |
Who is ineligible for warfarin in atrial fibrillation?
Topics: Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Drug Therapy, Combination; Humans; Patient Selection; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Warfarin | 2009 |
Testing a no-warfarin heart valve.
Topics: Anticoagulants; Aspirin; Clopidogrel; Heart Valve Diseases; Heart Valve Prosthesis; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Warfarin | 2006 |
Test before you stop.
Topics: Adenosine; Algorithms; Aspirin; Clinical Trials as Topic; Clopidogrel; Humans; Perioperative Care; Piperazines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prasugrel Hydrochloride; Pyridines; Risk Factors; Thiophenes; Ticagrelor; Ticlopidine | 2009 |
Challenge. What is your diagnosis? Answer. Primary nodal diffuse large B-cell lymphoma with secondary cutaneous involvement.
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Clopidogrel; Coronary Artery Disease; Diuretics; Exanthema; Humans; Hydrochlorothiazide; Lisinopril; Lymphoma, Large B-Cell, Diffuse; Male; Platelet Aggregation Inhibitors; Skin Neoplasms; Sotalol; Stents; Ticlopidine | 2009 |
Peri-operative management of anti-platelet agents.
Topics: Aged; Aged, 80 and over; Aspirin; Chi-Square Distribution; Clopidogrel; Female; Humans; Interviews as Topic; Male; Middle Aged; Platelet Aggregation Inhibitors; Preoperative Care; Surgical Procedures, Operative; Ticlopidine; Warfarin | 2009 |
Köhlmeier-Degos Disease (malignant atrophic papulosis) and neurologic involvement.
Topics: Adult; Aspirin; Brain Ischemia; Female; Fibrinolytic Agents; Humans; Malignant Atrophic Papulosis; Ticlopidine | 2009 |
Percutaneous coronary intervention in a patient with factor XI deficiency.
Topics: Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Factor XI Deficiency; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Treatment Outcome | 2009 |
Effect of blood hematocrit and erythrocyte deformability on adenosine 5'-diphosphate platelet reactivity in patients with acute coronary syndromes on dual antiplatelet therapy.
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Blood Viscosity; Clopidogrel; Erythrocyte Deformability; Female; Hematocrit; Humans; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Ticlopidine | 2009 |
One-year follow-up of nonrandomized comparison between coronary artery bypass grafting surgery and drug-eluting stent for the treatment of unprotected left main coronary artery disease in elderly patients (aged >or=75 years).
Topics: Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Confidence Intervals; Coronary Artery Bypass; Coronary Artery Disease; Drug-Eluting Stents; Female; Heparin; Humans; Logistic Models; Male; Multivariate Analysis; Odds Ratio; Platelet Aggregation Inhibitors; Prospective Studies; Stroke Volume; Ticlopidine; Time Factors; Ventricular Function, Left | 2009 |
Predictive value of post-treatment platelet reactivity for occurrence of post-discharge bleeding after non-ST elevation acute coronary syndrome. Shifting from antiplatelet resistance to bleeding risk assessment?
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Biomarkers; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Bypass; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Intracranial Hemorrhages; Male; Microfilament Proteins; Middle Aged; Patient Discharge; Phosphoproteins; Phosphorylation; Pilot Projects; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prospective Studies; Risk Assessment; Ticlopidine; Time Factors; Treatment Outcome | 2009 |
Early treatment for non-ST-segment elevation acute coronary syndrome is associated with appropriate discharge care.
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Aged; Aspirin; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Drug Utilization; Emergency Service, Hospital; Female; Guideline Adherence; Health Care Surveys; Health Services Accessibility; Humans; Male; Middle Aged; Outcome and Process Assessment, Health Care; Patient Discharge; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Practice Patterns, Physicians'; Registries; Retrospective Studies; Ticlopidine; Time Factors; Treatment Outcome; United States | 2009 |
Headache as the sole presenting symptom of acute myocardial infarction.
Topics: Angioplasty, Balloon, Coronary; Anticholesteremic Agents; Aspirin; Atorvastatin; Clopidogrel; Headache; Heparin, Low-Molecular-Weight; Heptanoic Acids; Humans; Male; Middle Aged; Myocardial Infarction; Oxygen Inhalation Therapy; Platelet Aggregation Inhibitors; Pyrroles; Ticlopidine | 2009 |
Retrospective analysis on the management of anticoagulants and antiplatelet agents for scheduled endoscopy.
Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Appointments and Schedules; Aspirin; Drug Monitoring; Drug Therapy, Combination; Drug Utilization; Endoscopy, Digestive System; Female; Guidelines as Topic; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Ticlopidine; Warfarin | 2009 |
Antiplatelet agents used for early intervention in acute coronary syndrome: myocardial salvage versus bleeding complications.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Coronary Artery Bypass; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Risk Factors; Ticlopidine | 2009 |
Clopidogrel plus aspirin in atrial fibrillation.
Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Contraindications; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Vitamin K; Warfarin | 2009 |
Clopidogrel plus aspirin in atrial fibrillation.
Topics: Aspirin; Atrial Fibrillation; Clopidogrel; Drug Therapy, Combination; Embolism; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Vascular Diseases | 2009 |
Clopidogrel plus aspirin in atrial fibrillation.
Topics: Aspirin; Atrial Fibrillation; Clopidogrel; Drug Costs; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Quality-Adjusted Life Years; Risk; Stroke; Ticlopidine | 2009 |
Clopidogrel plus aspirin in atrial fibrillation.
Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Incidence; Platelet Aggregation Inhibitors; Risk; Stroke; Ticlopidine; Vitamin K; Warfarin | 2009 |
Clopidogrel plus aspirin in atrial fibrillation.
Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Vitamin K | 2009 |
Clopidogrel plus aspirin in atrial fibrillation.
Topics: Aspirin; Atrial Fibrillation; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Stroke; Ticlopidine | 2009 |
Triple antiplatelet therapy for clopidogrel resistance with stent malapposition: a case report.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Drug-Eluting Stents; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Sirolimus; Ticlopidine; Tirofiban; Treatment Outcome; Tyrosine | 2009 |
Desensitization to clopidogrel: a growing need.
Topics: Aspirin; Cardiac Catheterization; Clopidogrel; Desensitization, Immunologic; Drug Therapy, Combination; Humans; Hyperlipidemias; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2010 |
Upper gastrointestinal bleeding in patients receiving dual antiplatelet therapy after coronary stenting.
Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Clopidogrel; Coronary Disease; Drug Interactions; Drug Therapy, Combination; Drug-Eluting Stents; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Retrospective Studies; Tetrazoles; Thrombosis; Ticlopidine; Treatment Outcome | 2009 |
Comparison of bleeding complications with omega-3 fatty acids + aspirin + clopidogrel--versus--aspirin + clopidogrel in patients with cardiovascular disease.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fatty Acids, Omega-3; Female; Follow-Up Studies; Hemorrhage; Humans; Incidence; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Ticlopidine; United States | 2009 |
Clinical benefit of early reperfusion therapy in patients with ST-elevation myocardial infarction usually excluded from randomized clinical trials (results from the Maximal Individual Therapy in Acute Myocardial Infarction Plus [MITRA Plus] registry).
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Clopidogrel; Electrocardiography; Female; Follow-Up Studies; Germany; Guideline Adherence; Hospital Mortality; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Myocardial Infarction; Myocardial Reperfusion; Odds Ratio; Platelet Aggregation Inhibitors; Prospective Studies; Randomized Controlled Trials as Topic; Registries; Ticlopidine; Treatment Outcome | 2009 |
The influence of clinical characteristics, laboratory and inflammatory markers on 'high on-treatment platelet reactivity' as measured with different platelet function tests.
Topics: Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Aspirin; Biomarkers; Blood Platelets; Cells, Cultured; Clopidogrel; Drug Combinations; Female; Humans; Interleukin-6; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Sensitivity and Specificity; Thrombosis; Ticlopidine | 2009 |
Utility of 96-well plate aggregometry and measurement of thrombi adhesion to determine aspirin and clopidogrel effectiveness.
Topics: Aspirin; Blood Platelets; Cells, Cultured; Clopidogrel; Drug Combinations; Feasibility Studies; Humans; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prognosis; Reproducibility of Results; Thrombosis; Ticlopidine; Treatment Outcome | 2009 |
Medical treatment of patients with intracranial atherosclerotic disease.
Topics: Anticoagulants; Aspirin; Atherosclerosis; Brain Ischemia; Cilostazol; Clopidogrel; Dipyridamole; Embolism; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracranial Arteriosclerosis; Intracranial Thrombosis; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Risk Factors; Tetrazoles; Ticlopidine | 2009 |
Cilostazol, a phosphodiesterase inhibitor, attenuates photothrombotic focal ischemic brain injury in hypertensive rats.
Topics: Animals; Aspirin; Brain Ischemia; Cells, Cultured; Cerebrovascular Circulation; Cilostazol; Clopidogrel; Endothelial Cells; Epoprostenol; Humans; Hypertension; Laser-Doppler Flowmetry; Male; Nitric Oxide; Phosphodiesterase Inhibitors; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Inbred SHR; Tetrazoles; Ticlopidine | 2010 |
Effects of clopidogrel on "aspirin specific" pathways of platelet inhibition.
Topics: Adenosine Diphosphate; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Blood Platelets; Clopidogrel; Drug Interactions; Female; Humans; Male; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2009 |
Early but not late stent thrombosis is influenced by residual platelet aggregation in patients undergoing coronary interventions.
Topics: Adolescent; Adult; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Graft Occlusion, Vascular; Humans; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Treatment Outcome; Young Adult | 2010 |
[Prasugrel or clopidogrel in patients with coronary intervention].
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Coronary Artery Bypass; Double-Blind Method; Endpoint Determination; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Piperazines; Platelet Aggregation Inhibitors; Thiophenes; Ticlopidine | 2009 |
Reduced platelet activity is associated with more intraventricular hemorrhage.
Topics: Adult; Aged; Aspirin; Blood Platelet Disorders; Blood Platelets; Cerebral Hemorrhage; Clopidogrel; Cohort Studies; Comorbidity; Disease Progression; Female; Humans; Lateral Ventricles; Male; Middle Aged; Outcome Assessment, Health Care; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine | 2009 |
Patient characteristics associated with the choice of triple antithrombotic therapy in acute coronary syndromes.
Topics: Acute Coronary Syndrome; Aged; Anemia; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Atrial Fibrillation; Atrial Flutter; Clopidogrel; Diabetes Mellitus; Drug Therapy, Combination; Drug Utilization; Female; Humans; Logistic Models; Male; Middle Aged; Patient Discharge; Platelet Aggregation Inhibitors; Registries; Smoking; Stents; Stroke; Stroke Volume; Ticlopidine; United States; Warfarin | 2009 |
Prevalence of unresponsiveness to aspirin and/or clopidogrel in patients with stable coronary heart disease.
Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Ticlopidine | 2009 |
A comparison of aspirin and clopidogrel with or without proton pump inhibitors for the secondary prevention of cardiovascular events in patients at high risk for gastrointestinal bleeding.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Clopidogrel; Databases, Factual; Drug Costs; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Patient Readmission; Peptic Ulcer; Platelet Aggregation Inhibitors; Proportional Hazards Models; Proton Pump Inhibitors; Retrospective Studies; Risk Factors; Secondary Prevention; Taiwan; Ticlopidine | 2009 |
Effect of clopidogrel on perioperative blood loss and transfusion in coronary artery bypass graft surgery.
Topics: Aged; Aspirin; Blood Transfusion; Cardiopulmonary Bypass; Clopidogrel; Coronary Artery Bypass; Drug Therapy, Combination; Female; Hemorrhage; Humans; Length of Stay; Male; Middle Aged; Patient Selection; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Retrospective Studies; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome | 2010 |
[Basic examination before clinical examination. That is why it is worthwhile to return to the laboratory].
Topics: Aspirin; Biomarkers; Blood Coagulation; CD40 Ligand; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Humans; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Punctures; Thrombin; Ticlopidine; Veins | 2009 |
The relation between platelet reactivity and glycemic control in diabetic patients with cardiovascular disease on maintenance aspirin and clopidogrel therapy.
Topics: Adult; Aged; Aspirin; Blood Glucose; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2009 |
Familial Takayasu's arteritis in female siblings.
Topics: Adult; Aorta, Thoracic; Aspirin; Clopidogrel; Family Health; Female; Genetic Predisposition to Disease; Humans; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Male; Middle Aged; Platelet Aggregation Inhibitors; Renal Artery; Siblings; Takayasu Arteritis; Ticlopidine; Tomography, X-Ray Computed | 2011 |
Platelet-bound P-selectin expression in patients with coronary artery disease: impact on clinical presentation and myocardial necrosis, and effect of diabetes mellitus and anti-platelet medication.
Topics: Acute Coronary Syndrome; Angina Pectoris; Aspirin; Biomarkers; Blood Platelets; Clopidogrel; Coronary Artery Disease; Creatine Kinase, MB Form; Diabetes Mellitus; Drug Therapy, Combination; Flow Cytometry; Humans; Myocardium; Necrosis; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors; Treatment Outcome; Troponin I; Up-Regulation | 2010 |
Prasugrel: new drug. After angioplasty and stenting: continue to use aspirin + clopidogrel.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Drug-Eluting Stents; Europe; Hemorrhage; Humans; Ischemic Attack, Transient; Myocardial Infarction; Neoplasms; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Randomized Controlled Trials as Topic; Receptors, Purinergic P2; Recurrence; Stents; Stroke; Thiophenes; Ticlopidine; Treatment Outcome | 2009 |
Platelet monitoring for PCI: which test is the one to choose?
Topics: Acute Coronary Syndrome; Aspirin; Blood Platelets; Clopidogrel; Electric Impedance; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Prognosis; Thromboxane B2; Ticlopidine | 2009 |
Pro: "Anti-platelet therapy is an alternative to oral anticoagulation for atrial fibrillation".
Topics: Administration, Oral; Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Clinical Trials as Topic; Clopidogrel; Contraindications; Drug Therapy, Combination; Hemorrhage; Humans; International Normalized Ratio; Intracranial Embolism; Middle Aged; Multicenter Studies as Topic; Platelet Aggregation Inhibitors; Risk Factors; Severity of Illness Index; Thrombophilia; Ticlopidine; Warfarin | 2009 |
Contra: "Anti-platelet therapy is an alternative to oral anticoagulation for atrial fibrillation".
Topics: Administration, Oral; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Clinical Trials as Topic; Clopidogrel; Contraindications; Drug Therapy, Combination; Hemorrhage; Humans; Intracranial Embolism; Middle Aged; Multicenter Studies as Topic; Platelet Aggregation Inhibitors; Risk Factors; Severity of Illness Index; Thrombophilia; Ticlopidine; Vitamin K; Warfarin | 2009 |
Effectiveness of two-year clopidogrel + aspirin in abolishing the risk of very late thrombosis after drug-eluting stent implantation (from the TYCOON [two-year ClOpidOgrel need] study).
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Thrombosis; Drug Therapy, Combination; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Male; Platelet Aggregation Inhibitors; Prospective Studies; Registries; Stents; Ticlopidine; Time Factors | 2009 |
Perioperative management of the patient with a coronary stent.
Topics: Algorithms; Aspirin; Clopidogrel; Coronary Thrombosis; Drug Therapy, Combination; Drug-Eluting Stents; Graft Occlusion, Vascular; Humans; Perioperative Care; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine; Time Factors | 2010 |
Gender and responses to aspirin and clopidogrel: insights using short thrombelastography.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Sex Characteristics; Thrombelastography; Ticlopidine | 2009 |
Letter by Kan et al regarding Article, "randomized trial of warfarin, aspirin, and clopidogrel in patients with chronic heart failure: the Warfarin and Antiplatelet Therapy in Chronic Heart failure (WATCH) trial".
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Chronic Disease; Clopidogrel; Death; Double-Blind Method; Female; Fibrinolytic Agents; Heart Failure; Humans; Male; Middle Aged; Myocardial Infarction; Stroke; Stroke Volume; Ticlopidine; Warfarin | 2009 |
By the way, doctor. I am currently on Coumadin because I had atrial fibrillation after my bypass, Plavix because of my stent, and a baby aspirin. Why do I need to take three blood thinners?
Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Cardiopulmonary Bypass; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Warfarin | 2009 |
ProFESS trial: any lessons to learn for future anti-platelet trials?
Topics: Aged; Aspirin; Brain; Cerebral Arteries; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Risk Reduction Behavior; Stroke; Ticlopidine | 2009 |
Aspirin and clopidogrel use in the early postoperative period following on-pump and off-pump coronary artery bypass grafting.
Topics: Adult; Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Artery Bypass, Off-Pump; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Postoperative Period; Ticlopidine | 2009 |
Aspirin gets a backup against atrial fibrillation.
Topics: Aspirin; Atrial Fibrillation; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2009 |
Multiple electrode aggregometry predicts stent thrombosis better than the vasodilator-stimulated phosphoprotein phosphorylation assay.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Biomarkers; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Electrodes; Female; Humans; Logistic Models; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prospective Studies; ROC Curve; Sensitivity and Specificity; Stents; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2010 |
There is no place like home after successful percutaneous coronary intervention.
Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Evidence-Based Medicine; Hemorrhage; Humans; Immunoglobulin Fab Fragments; Infusions, Parenteral; Injections; Length of Stay; Myocardial Infarction; Patient Discharge; Platelet Aggregation Inhibitors; Radial Artery; Risk Assessment; Risk Factors; Stents; Ticlopidine; Time Factors; Treatment Outcome | 2009 |
Dual antiplatelet therapy in patients requiring urgent coronary artery bypass grafting surgery: a position statement of the Canadian Cardiovascular Society.
Topics: Acute Coronary Syndrome; Aspirin; Canada; Clopidogrel; Coronary Artery Bypass; Drug Therapy, Combination; Health Planning Guidelines; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Risk Factors; Societies, Medical; Ticlopidine; Treatment Outcome | 2009 |
A regional system for delivery of primary percutaneous coronary intervention in ST-elevation myocardial infarction: STEMI-St. Cloud.
Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Delivery of Health Care; Electrocardiography; Female; Follow-Up Studies; Heparin; Humans; Male; Middle Aged; Minnesota; Myocardial Infarction; Patient Transfer; Platelet Aggregation Inhibitors; Registries; Retrospective Studies; Survival Rate; Ticlopidine; Time Factors; Treatment Outcome | 2009 |
The role of transcranial Doppler embolic monitoring in the management of intracranial arterial stenosis.
Topics: Angiography, Digital Subtraction; Aspirin; Atorvastatin; Blood Flow Velocity; Cerebral Angiography; Clopidogrel; Constriction, Pathologic; Diagnosis, Differential; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracranial Embolism; Ischemic Attack, Transient; Magnetic Resonance Imaging; Platelet Aggregation Inhibitors; Pyrroles; Ticlopidine; Tomography, X-Ray Computed; Ultrasonography, Doppler, Transcranial; Young Adult | 2011 |
The right oral antithrombotics in acute coronary syndromes.
Topics: Acute Coronary Syndrome; Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Prognosis; Ticlopidine; Vitamin K | 2009 |
Risk of bleeding in patients with acute myocardial infarction treated with different combinations of aspirin, clopidogrel, and vitamin K antagonists in Denmark: a retrospective analysis of nationwide registry data.
Topics: Adult; Aged; Aspirin; Clopidogrel; Denmark; Drug Therapy, Combination; Female; Follow-Up Studies; Hemorrhage; Humans; Incidence; Male; Middle Aged; Myocardial Infarction; Patient Admission; Proportional Hazards Models; Recurrence; Registries; Retrospective Studies; Risk Factors; Ticlopidine; Vitamin K | 2009 |
eComment: Controversies on the antiplatelet therapy before coronary artery bypass grafting surgery.
Topics: Aspirin; Blood Transfusion; Cardiopulmonary Bypass; Clopidogrel; Coronary Artery Bypass; Drug Therapy, Combination; Hemorrhage; Humans; Patient Selection; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome | 2010 |
Antiplatelet drugs for patients at high cardiovascular risk. Aspirin generally remains the best choice.
Topics: Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; Atrial Fibrillation; Brain Ischemia; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Humans; Myocardial Infarction; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Risk; Stents; Stroke; Thromboembolism; Thrombosis; Ticlopidine; Warfarin | 2009 |
Should dual antiplatelet therapy after drug-eluting stents be continued for more than 1 year?: Dual antiplatelet therapy after drug-eluting stents should be continued for more than one year and preferably indefinitely.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Restenosis; Coronary Thrombosis; Drug Therapy, Combination; Drug-Eluting Stents; Hemorrhage; Humans; Myocardial Infarction; Patient Selection; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors | 2008 |
Should dual antiplatelet therapy after drug-eluting stents be continued for more than 1 year?: Dual antiplatelet therapy after drug-eluting stents should not be continued for more than 1 year and preferably indefinitely.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Blood Loss, Surgical; Clopidogrel; Coronary Restenosis; Coronary Thrombosis; Drug Therapy, Combination; Drug-Eluting Stents; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors | 2008 |
Clopidogrel for the hot patient.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Biomarkers; C-Reactive Protein; Clopidogrel; Drug Therapy, Combination; Humans; Inflammation; Inflammation Mediators; Myocardial Infarction; Platelet Aggregation Inhibitors; Predictive Value of Tests; Pregnancy-Associated Plasma Protein-A; Risk Assessment; Stroke; Ticlopidine; Time Factors; Treatment Outcome; Up-Regulation | 2009 |
Relationship between baseline inflammatory markers, antiplatelet therapy, and adverse cardiac events after percutaneous coronary intervention: an analysis from the clopidogrel for the reduction of events during observation trial.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Biomarkers; C-Reactive Protein; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Inflammation; Inflammation Mediators; Kaplan-Meier Estimate; Male; Middle Aged; Multicenter Studies as Topic; Myocardial Infarction; Patient Selection; Platelet Aggregation Inhibitors; Predictive Value of Tests; Pregnancy-Associated Plasma Protein-A; Proportional Hazards Models; Prospective Studies; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Assessment; Stroke; Ticlopidine; Time Factors; Treatment Outcome; United States; Up-Regulation | 2009 |
Imaging of structural changes in endothelial cells and thrombus formation at the site of FeCl(3)-induced injuries in mice cremasteric arteries.
Topics: Animals; Arteries; Aspirin; Blood Platelets; Chlorides; Clopidogrel; Dose-Response Relationship, Drug; Endothelial Cells; Ferric Compounds; Leukocytes; Male; Mice; Mice, Inbred ICR; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine | 2009 |
Frontiers in platelet inhibition.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Humans; Models, Biological; Platelet Aggregation Inhibitors; Receptors, Purinergic P2; Ticlopidine | 2009 |
Acute coronary syndrome.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Critical Pathways; Electrocardiography; Emergency Treatment; Guideline Adherence; Humans; Patient Selection; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Risk Assessment; Ticlopidine | 2009 |
Guidelines for the management of antiplatelet therapy in patients with coronary stents undergoing non-cardiac surgery.
Topics: Anticoagulants; Aspirin; Australia; Clopidogrel; Coronary Thrombosis; Drug-Eluting Stents; Heparin; Humans; New Zealand; Platelet Aggregation Inhibitors; Preoperative Care; Ticlopidine | 2010 |
[Abdominal tumor after persistent coughing and uncontrolled anticoagulation].
Topics: Abdomen, Acute; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Colonic Pseudo-Obstruction; Comorbidity; Cough; Dalteparin; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Hematoma; Humans; Intracranial Embolism; Phenprocoumon; Rectus Abdominis; Ticlopidine | 2010 |
Safety of intravenous thrombolysis for acute ischemic stroke in patients receiving antiplatelet therapy at stroke onset.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Brain Ischemia; Cerebral Hemorrhage; Clopidogrel; Contraindications; Dipyridamole; Drug Incompatibility; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; Fibrinolytic Agents; Humans; Incidence; Injections, Intravenous; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Assessment; Stroke; Ticlopidine; Tissue Plasminogen Activator; Treatment Outcome; Young Adult | 2010 |
The relationship between warfarin, aspirin, and clopidogrel continuation in the peri-procedural period and the incidence of hematoma formation after device implantation.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Clopidogrel; Defibrillators, Implantable; Female; Hematoma; Humans; International Normalized Ratio; Male; Pacemaker, Artificial; Perioperative Care; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Prosthesis Implantation; Retrospective Studies; Ticlopidine; Warfarin | 2010 |
Cost-effectiveness of clopidogrel in STEMI patients in the Netherlands: a model based on the CLARITY trial.
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Costs and Cost Analysis; Female; Humans; Male; Models, Theoretical; Multicenter Studies as Topic; Myocardial Infarction; Netherlands; Platelet Aggregation Inhibitors; Ticlopidine | 2010 |
Subacute coronary stent thrombosis in a patient with angina treated with double antiplatelet drugs for six days.
Topics: Adult; Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Thrombosis; Drug-Eluting Stents; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine | 2009 |
Risk profile and benefits from Gp IIb-IIIa inhibitors among patients with ST-segment elevation myocardial infarction treated with primary angioplasty: a meta-regression analysis of randomized trials.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Meta-Analysis as Topic; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Randomized Controlled Trials as Topic; Ticlopidine; Treatment Failure | 2010 |
Anxiety is a better predictor of platelet reactivity in coronary artery disease patients than depression.
Topics: Adenosine Diphosphate; Aged; Angina, Unstable; Anxiety Disorders; Aspirin; Clopidogrel; Cross-Sectional Studies; Depressive Disorder; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Serotonin; Ticlopidine | 2010 |
Initial experience with dual antiplatelet thromboprophylaxis using clopidogrel and aspirin in patients with mechanical aortic prostheses.
Topics: Aged; Aortic Valve; Aspirin; Blood Platelets; Clopidogrel; Drug Combinations; Female; Follow-Up Studies; Heart Diseases; Heart Valve Prosthesis; Heart Valve Prosthesis Implantation; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Puerto Rico; Thromboembolism; Ticlopidine; United States | 2009 |
Relation of endothelial function to residual platelet reactivity after clopidogrel in patients with stable angina pectoris undergoing percutaneous coronary intervention.
Topics: Aged; Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; Biomarkers; Blood Platelets; Clopidogrel; Drug Therapy, Combination; Endothelium, Vascular; Female; Humans; Male; Manometry; Middle Aged; P-Selectin; Platelet Aggregation Inhibitors; Prospective Studies; Severity of Illness Index; Ticlopidine; Time Factors; Treatment Failure; Treatment Outcome; Troponin T | 2010 |
Benefit assessment in Germany.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Comparative Effectiveness Research; Germany; Government Agencies; Humans; Hypoglycemic Agents; Insulin; Insulin Glargine; Insulin, Long-Acting; National Health Programs; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine | 2010 |
Safety of carotid endarterectomy while on clopidogrel (Plavix). Clinical article.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Clopidogrel; Cohort Studies; Edema; Endarterectomy, Carotid; Female; Hemorrhage; Humans; International Normalized Ratio; Male; Middle Aged; Partial Thromboplastin Time; Platelet Aggregation Inhibitors; Postoperative Complications; Prothrombin Time; Retrospective Studies; Risk; Stroke; Ticlopidine | 2010 |
Clinical outcome after acute coronary syndrome in Japanese patients: an observational cohort study.
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Age Factors; Aged; Angioplasty, Balloon, Coronary; Aspirin; Cohort Studies; Coronary Artery Bypass; Female; Glomerular Filtration Rate; Humans; Japan; Male; Ticlopidine | 2010 |
Efficacy of modified dual antiplatelet therapy combined with warfarin following percutaneous coronary intervention with drug-eluting stents.
Topics: Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Combined Modality Therapy; Coronary Artery Disease; Coronary Restenosis; Coronary Thrombosis; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Retrospective Studies; Ticlopidine; Treatment Outcome; Warfarin | 2010 |
Very late drug-eluting stent thrombosis in the perioperative period of endoscopic choledocholithotomy.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug-Eluting Stents; Endoscopy, Digestive System; Gallstones; Humans; Male; Middle Aged; Perioperative Care; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors | 2009 |
Adrenergic receptor polymorphisms and platelet reactivity after treatment with dual antiplatelet therapy with aspirin and clopidogrel in acute coronary syndrome.
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Aged; Aspirin; Cell Adhesion Molecules; Chi-Square Distribution; Clopidogrel; Drug Therapy, Combination; Female; Gene Frequency; Genotype; Humans; Linear Models; Male; Microfilament Proteins; Middle Aged; Phenotype; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Single Nucleotide; Prospective Studies; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta-2; Ticlopidine; Treatment Outcome | 2010 |
Lack of complications in skin surgery of patients receiving clopidogrel as compared with patients taking aspirin, warfarin, and controls.
Topics: Aged; Anticoagulants; Aspirin; Case-Control Studies; Clopidogrel; Dermatologic Surgical Procedures; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Erythema; Female; Follow-Up Studies; Hematoma; Humans; Male; Platelet Aggregation Inhibitors; Postoperative Complications; Surgical Wound Dehiscence; Surgical Wound Infection; Ticlopidine; Warfarin | 2010 |
Serum thromboxane B2 compared to five other platelet function tests for the evaluation of aspirin effect in stable cardiovascular disease.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Pressure; Cardiovascular Diseases; Case-Control Studies; Clopidogrel; Female; Fish Oils; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Statistics as Topic; Statistics, Nonparametric; Surveys and Questionnaires; Thromboxane B2; Ticlopidine | 2010 |
Safety of drug eluting stents in patients on chronic anticoagulation using long-term single antiplatelet treatment with clopidogrel.
Topics: Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Ticlopidine | 2010 |
[Perioperative management of patients with coronary stents in non-cardiac surgery].
Topics: Aspirin; Clopidogrel; Coronary Vessels; Drug-Eluting Stents; Elective Surgical Procedures; Guidelines as Topic; Humans; Perioperative Care; Platelet Aggregation Inhibitors; Risk Assessment; Stents; Surgical Procedures, Operative; Thrombosis; Ticlopidine | 2010 |
Triple antiplatelet therapy reduces ischemic events after drug-eluting stent implantation: Drug-Eluting stenting followed by Cilostazol treatment REduces Adverse Serious cardiac Events (DECREASE registry).
Topics: Aspirin; Cilostazol; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Tetrazoles; Thrombosis; Ticlopidine; Time Factors | 2010 |
Triple therapy: triple safety or triple danger?
Topics: Administration, Oral; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Drug Tolerance; Evidence-Based Medicine; Humans; Platelet Aggregation Inhibitors; Risk Assessment; Stents; Thromboembolism; Ticlopidine; Treatment Outcome | 2010 |
[Non-occlusive stent thrombosis associated to cardiocirculatory arrest].
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Restenosis; Drug-Eluting Stents; Electroencephalography; Female; Heart Arrest; Humans; Myocardial Ischemia; Platelet Aggregation Inhibitors; Ticlopidine | 2010 |
Oral anticoagulation with coumarin derivatives and antiplatelet effects of clopidogrel.
Topics: Adenosine Diphosphate; Administration, Oral; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coronary Artery Disease; Cross-Sectional Studies; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Multivariate Analysis; Phenprocoumon; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2010 |
The dental implant patient on anticoagulant therapy.
Topics: Anticoagulants; Aspirin; Clopidogrel; Dental Care for Chronically Ill; Dental Implantation, Endosseous; Heparin; Ticlopidine; Warfarin | 2010 |
Long-term effectiveness and safety of sirolimus stent implantation for coronary in-stent restenosis results of the TRUE (Tuscany Registry of sirolimus for unselected in-stent restenosis) registry at 4 years.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Agents; Clopidogrel; Coronary Restenosis; Coronary Thrombosis; Creatinine; Diabetes Mellitus; Drug-Eluting Stents; Follow-Up Studies; Humans; Myocardial Infarction; Myocardial Revascularization; Platelet Aggregation Inhibitors; Prospective Studies; Registries; Sirolimus; Stroke Volume; Ticlopidine | 2010 |
Inconsistent trial assessments by the National Institute for Health and Clinical Excellence and IQWiG: standards for the performance and interpretation of subgroup analyses are needed.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; England; Evidence-Based Medicine; Germany; Humans; Intention to Treat Analysis; Randomized Controlled Trials as Topic; Research Design; Ticlopidine | 2010 |
Impact of high-responsiveness to dual antiplatelet therapy on bleeding complications in patients receiving drug-eluting stents.
Topics: Aged; Angioplasty, Balloon, Laser-Assisted; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Female; Follow-Up Studies; Hemorrhage; Humans; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation Inhibitors; Pyridines; Retrospective Studies; Risk Factors; Ticlopidine; Treatment Outcome | 2010 |
[Cardiac workup after cerebral ischemia. Consensus paper of the Working Group on Heart and Brain of the German Cardiac Society and German Stroke Society].
Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Brain Ischemia; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Echocardiography; Electrocardiography, Ambulatory; Embolism; Exercise Test; Humans; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine; Warfarin | 2010 |
Positional brain ischemia with MCA occlusion successfully treated with extra-intracranial bypass.
Topics: Aspirin; Cerebral Revascularization; Clopidogrel; Humans; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Magnetic Resonance Imaging; Male; Middle Aged; Middle Cerebral Artery; Paresis; Parietal Lobe; Platelet Aggregation Inhibitors; Posture; Temporal Arteries; Thrombophilia; Ticlopidine; Tomography, Emission-Computed, Single-Photon | 2010 |
Antithrombotic activity of F 16618, a new PAR1 antagonist evaluated in extracorporeal arterio-venous shunt in the rat.
Topics: Animals; Arterial Occlusive Diseases; Arteriovenous Shunt, Surgical; Aspirin; Bleeding Time; Clopidogrel; Dose-Response Relationship, Drug; Fibrinolytic Agents; Humans; Male; Piperazines; Platelet Aggregation; Pyridines; Rats; Receptor, PAR-1; Thrombosis; Ticlopidine | 2010 |
[The effect of different dosage of aspirin on inflammatory biomarkers and prognosis in acute coronary syndrome.].
Topics: Acute Coronary Syndrome; Aspirin; Biomarkers; Humans; Platelet Aggregation Inhibitors; Prognosis; Risk Factors; Ticlopidine | 2009 |
Fecal occult blood test in patients on low-dose aspirin, warfarin, clopidogrel, or non-steroidal anti-inflammatory drugs.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Clopidogrel; Colonic Neoplasms; Colonoscopy; Female; Gastrointestinal Hemorrhage; Humans; Logistic Models; Male; Mass Screening; Middle Aged; Occult Blood; Odds Ratio; Platelet Aggregation Inhibitors; Predictive Value of Tests; Retrospective Studies; Ticlopidine; Unnecessary Procedures; Warfarin | 2010 |
Impact of persistence with antiplatelet therapy on recurrent ischemic stroke and predictors of nonpersistence among ischemic stroke survivors.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Brain Ischemia; Clopidogrel; Dipyridamole; Female; Humans; Male; Middle Aged; Patient Compliance; Platelet Aggregation Inhibitors; Recurrence; Retrospective Studies; Stroke; Survivors; Ticlopidine; Treatment Outcome; Young Adult | 2010 |
Evaluation of antiplatelet effects of a modified protocol by platelet aggregation in patients undergoing "one-stop" hybrid coronary revascularization.
Topics: Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Arachidonic Acid; Aspirin; Clopidogrel; Combined Modality Therapy; Coronary Artery Bypass; Coronary Artery Disease; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Prospective Studies; Ticlopidine | 2010 |
Comparison of different antithrombotic regimens for patients with atrial fibrillation undergoing drug-eluting stent implantation.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Female; Fibrinolytic Agents; Follow-Up Studies; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Prospective Studies; Risk Factors; Stroke; Thromboembolism; Ticlopidine; Treatment Outcome; Warfarin | 2010 |
Clinical relevance of clopidogrel unresponsiveness during elective coronary stenting: experience with the point-of-care platelet function assay-100 C/ADP.
Topics: Administration, Oral; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Vessels; Death, Sudden, Cardiac; Drug Resistance; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Predictive Value of Tests; Preoperative Care; Prospective Studies; Risk Factors; Stents; Thrombosis; Ticlopidine; Time Factors | 2010 |
Relation of proton pump inhibitor use after percutaneous coronary intervention with drug-eluting stents to outcomes.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug-Eluting Stents; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Survival Rate; Ticlopidine | 2010 |
Letter by Doraiswamy regarding article, "Intensifying platelet inhibition with tirofiban in poor responders to aspirin, clopidogrel, or both agents undergoing elective coronary intervention: results from the double-blind, prospective, randomized Tailoring
Topics: Anticoagulants; Aspirin; Clopidogrel; Confounding Factors, Epidemiologic; Double-Blind Method; Drug Resistance; Elective Surgical Procedures; Hemorrhage; Heparin; Humans; Myocardial Revascularization; Patient Selection; Platelet Aggregation Inhibitors; Postoperative Complications; Randomized Controlled Trials as Topic; Research Design; Thromboembolism; Ticlopidine; Tirofiban; Tyrosine | 2010 |
Acute myocardial infarction related to very late sirolimus-eluting stent thrombosis 6 months after discontinuation of dual antiplatelet therapy.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Agents; Clopidogrel; Coronary Angiography; Coronary Thrombosis; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Prosthesis Design; Sirolimus; Ticlopidine; Time Factors | 2011 |
Trial watch. DAPT study.
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Male; Multicenter Studies as Topic; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Ticlopidine | 2010 |
[Comment about patients with dual antiplatelet therapy].
Topics: Anticoagulants; Aspirin; Blood Loss, Surgical; Clopidogrel; Contraindications; Drug Therapy, Combination; Elective Surgical Procedures; Humans; Myocardial Revascularization; Platelet Aggregation Inhibitors; Postoperative Complications; Postoperative Hemorrhage; Preoperative Care; Thromboembolism; Ticlopidine | 2010 |
Impact of chronic kidney disease on platelet function profiles in diabetes mellitus patients with coronary artery disease taking dual antiplatelet therapy.
Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cross-Sectional Studies; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine; Treatment Outcome | 2010 |
The loading dose of clopidogrel in patients with ST-segment elevation myocardial infarction undergoing primary angioplasty.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon; Aspirin; Clopidogrel; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine | 2010 |
Long-term aspirin and clopidogrel response evaluated by light transmission aggregometry, VerifyNow, and thrombelastography in patients undergoing percutaneous coronary intervention.
Topics: Adult; Aspirin; Clopidogrel; Female; Follow-Up Studies; Humans; Male; Platelet Aggregation Inhibitors; Platelet Function Tests; Thrombelastography; Ticlopidine | 2010 |
Changes in platelets and anticoagulant protein activity during adenosine-exercise single-photon emission computed tomography stress test.
Topics: Adenosine; Adenosine Diphosphate; Adult; Aged; Antithrombins; Aspirin; beta-Thromboglobulin; Blood Coagulation; Clopidogrel; Coronary Stenosis; Epinephrine; Exercise Test; Female; Humans; Male; Middle Aged; Myocardial Perfusion Imaging; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Factor 4; Protein C; Ticlopidine; Tomography, Emission-Computed, Single-Photon; Vasodilator Agents | 2010 |
[Multicentric study of thrombosis prevention in upper-extremity microsurgery. Survey at the Fesum centers].
Topics: Aspirin; Clopidogrel; Drug Monitoring; Evidence-Based Practice; Fibrinolytic Agents; France; Hemorrhage; Heparin; Humans; Microsurgery; Perioperative Care; Platelet Aggregation Inhibitors; Practice Patterns, Physicians'; Pyrrolidines; Research Design; Risk Factors; Skin Transplantation; Surgical Flaps; Thrombosis; Ticlopidine; Upper Extremity | 2010 |
Preliminary evidence of a high risk of bleeding on aspirin plus clopidogrel in aspirin-naïve patients in the acute phase after TIA or minor ischaemic stroke.
Topics: Aged; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Hemorrhage; Humans; Incidence; Ischemic Attack, Transient; Longitudinal Studies; Male; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Stroke; Ticlopidine | 2010 |
Time matters for reducing risk of stroke.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Risk; Stroke; Ticlopidine | 2010 |
Antiplatelet drugs and risk of subarachnoid hemorrhage: a population-based case-control study.
Topics: Adolescent; Adult; Aged; Aspirin; Case-Control Studies; Clopidogrel; Denmark; Dipyridamole; Female; Humans; Male; Middle Aged; Odds Ratio; Platelet Aggregation Inhibitors; Registries; Risk; Subarachnoid Hemorrhage; Ticlopidine; Time Factors; Young Adult | 2010 |
Early and intermediate outcomes of left main coronary intervention.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Disease; Coronary Vessels; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Stents; Survival; Ticlopidine; Time Factors; Treatment Outcome; Ultrasonography; Ventricular Function, Left | 2010 |
Non-invasive coronary flow reserve after successful primary angioplasty for acute anterior myocardial infarction is an independent predictor of left ventricular adverse remodelling.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Echocardiography; Female; Fractional Flow Reserve, Myocardial; Heart Ventricles; Hemodynamics; Humans; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Platelet Aggregation Inhibitors; Prognosis; Risk Assessment; ROC Curve; Sensitivity and Specificity; Statistics as Topic; Stroke Volume; Ticlopidine; Ventricular Function, Left | 2010 |
I had two stents put in during the past year, but I'm going to have a hip replacement soon. Are there any heart-related or stent related precautions my doctor and I should take before the surgery?
Topics: Angioplasty, Balloon, Coronary; Arthroplasty, Replacement, Hip; Aspirin; Clopidogrel; Drug-Eluting Stents; Health Knowledge, Attitudes, Practice; Humans; Platelet Aggregation Inhibitors; Postoperative Complications; Preoperative Care; Stents; Ticlopidine | 2009 |
[Balancing act in antithrombotic therapy. Between hemorrhage and embolism].
Topics: Angioplasty, Balloon, Coronary; Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Disease; Coronary Restenosis; Drug Interactions; Drug Therapy, Combination; Fibrinolytic Agents; Hemorrhage; Humans; Phenprocoumon; Proton Pump Inhibitors; Stents; Thromboembolism; Ticlopidine | 2010 |
Late common iliac artery stent thrombosis in a patient with terminal malignancy.
Topics: Aged; Angiography; Aspirin; Atherosclerosis; Carcinoma, Renal Cell; Clopidogrel; Humans; Iliac Artery; Kidney Neoplasms; Male; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine | 2010 |
Comment on "variations in the pharmacological management of patients treated with carotid endarterectomy: a survey of European vascular surgeons".
Topics: Aspirin; Carotid Artery Diseases; Clopidogrel; Endarterectomy, Carotid; Europe; Humans; Incidence; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Prognosis; Risk Factors; Secondary Prevention; Surveys and Questionnaires; Ticlopidine | 2010 |
[Clopidogrel treatment and elective non-cardiac surgery].
Topics: Aspirin; Clopidogrel; Elective Surgical Procedures; Humans; Platelet Aggregation Inhibitors; Risk Assessment; Ticlopidine | 2010 |
Dysfunction of a 21-mm aortic bioprosthesis treated with percutaneous implantation of a CoreValve prosthesis.
Topics: Aged, 80 and over; Aortic Valve; Aortic Valve Stenosis; Aspirin; Calcinosis; Clopidogrel; Combined Modality Therapy; Echocardiography; Echocardiography, Transesophageal; Female; Follow-Up Studies; Heart Valve Prosthesis Implantation; Humans; Platelet Aggregation Inhibitors; Prosthesis Failure; Risk Factors; Ticlopidine; Tomography, X-Ray Computed; Treatment Outcome | 2013 |
Relationship between chronic obstructive pulmonary disease and in-hospital management and outcomes in patients with acute myocardial infarction.
Topics: Aged; Aspirin; Clopidogrel; Comorbidity; Female; Health Services Accessibility; Hospital Mortality; Humans; Male; Myocardial Infarction; Poland; Pulmonary Disease, Chronic Obstructive; Risk Management; Ticlopidine; Treatment Outcome | 2010 |
[Thrombosis of pharmacoactive coronary endoprothesis after stopping antiplatelet treatment].
Topics: Angioplasty, Balloon, Coronary; Aspirin; Cholecystectomy, Laparoscopic; Cholecystolithiasis; Clopidogrel; Coronary Thrombosis; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine; Treatment Outcome | 2010 |
Usefulness of monitoring platelet function by multiple electrode aggregometry in primary coronary artery bypass surgery.
Topics: Aged; Anesthesia, General; Aspirin; Blood Transfusion; Blood Volume; Clopidogrel; Coronary Artery Bypass; Erythrocyte Transfusion; Female; Humans; Hydroxyethyl Starch Derivatives; Male; Middle Aged; Monitoring, Intraoperative; Plasma Substitutes; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Postoperative Care; Postoperative Hemorrhage; Preanesthetic Medication; Prospective Studies; ROC Curve; Ticlopidine; Treatment Outcome | 2011 |
Cardiorenal syndromes--recommendations from clinical practice guidelines: the cardiologist's view.
Topics: Acute Disease; Acute Kidney Injury; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Chronic Disease; Clopidogrel; Heart Failure; Humans; Kidney Failure, Chronic; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Renal Insufficiency; Shock, Cardiogenic; Stroke Volume; Syndrome; Ticlopidine | 2010 |
Probing the occult: testing for blood in the stools.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Clopidogrel; Colonic Neoplasms; Colonoscopy; Gastrointestinal Hemorrhage; Humans; Mass Screening; Occult Blood; Platelet Aggregation Inhibitors; Predictive Value of Tests; Ticlopidine; Unnecessary Procedures; Warfarin | 2010 |
Incidence, correlates, and clinical impact of nuisance bleeding after antiplatelet therapy for patients with drug-eluting stents.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Drug-Eluting Stents; Female; Hemorrhage; Humans; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Ticlopidine | 2010 |
Dual low response to acetylsalicylic acid and clopidogrel is associated with myonecrosis and stent thrombosis after coronary stent implantation.
Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Multivariate Analysis; Myocardium; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2010 |
Role of triple antithrombotic therapy in patients with atrial fibrillation and coronary artery stents.
Topics: Algorithms; Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Vessels; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Management; Stents; Ticlopidine; Warfarin | 2010 |
Dual antiplatelet therapy prior to carotid endarterectomy reduces post-operative embolisation and thromboembolic events: post-operative transcranial Doppler monitoring is now unnecessary.
Topics: Aged; Angioscopy; Anticoagulants; Aspirin; Clopidogrel; Dextrans; Drug Therapy, Combination; Endarterectomy, Carotid; Female; Fibrinolytic Agents; Humans; Male; Medical Audit; Platelet Aggregation Inhibitors; Postoperative Complications; Preoperative Care; Retrospective Studies; Thromboembolism; Ticlopidine; Ultrasonography, Doppler, Transcranial | 2010 |
Synergistic effect of a factor Xa inhibitor, TAK-442, and antiplatelet agents on whole blood coagulation and arterial thrombosis in rats.
Topics: Animals; Aspirin; Blood Coagulation; Blood Coagulation Tests; Clopidogrel; Drug Synergism; Factor Xa Inhibitors; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrimidinones; Rats; Rats, Sprague-Dawley; Sulfones; Thrombosis; Ticlopidine | 2010 |
PPI use in patients commenced on clopidogrel: a retrospective cross-sectional evaluation.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Cohort Studies; Cross-Sectional Studies; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Northern Territory; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Retrospective Studies; Risk Factors; Tasmania; Ticlopidine; Young Adult | 2010 |
Rotablation in the drug eluting era: immediate and long-term results from a single center experience.
Topics: Aged; Angioplasty, Balloon, Coronary; Angioplasty, Balloon, Laser-Assisted; Aspirin; Atherectomy, Coronary; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Female; Humans; Male; Platelet Aggregation Inhibitors; Retrospective Studies; Ticlopidine; Time Factors; Treatment Outcome | 2010 |
Withdrawal of clopidogrel in active gastric bleeding.
Topics: Aspirin; Cardiovascular Diseases; Cerebrovascular Disorders; Clopidogrel; Gastrointestinal Hemorrhage; Humans; Peptic Ulcer; Platelet Aggregation Inhibitors; Research Design; Ticlopidine | 2010 |
Dual antiplatelet therapy and heparin "bridging" significantly increase the risk of bleeding complications after pacemaker or implantable cardioverter-defibrillator device implantation.
Topics: Aged; Aged, 80 and over; Aspirin; Case-Control Studies; Clopidogrel; Confidence Intervals; Defibrillators, Implantable; Drug Therapy, Combination; Female; Follow-Up Studies; Heparin; Humans; Length of Stay; Male; Middle Aged; Odds Ratio; Pacemaker, Artificial; Platelet Aggregation Inhibitors; Postoperative Care; Postoperative Hemorrhage; Prevalence; Reference Values; Retrospective Studies; Risk Assessment; Ticlopidine; Warfarin | 2010 |
Isolated and interactive impact of common CYP2C19 genetic variants on the antiplatelet effect of chronic clopidogrel therapy.
Topics: Aged; Alleles; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Cohort Studies; Cytochrome P-450 CYP2C19; Female; Genetic Variation; Humans; Male; Middle Aged; Pharmacogenetics; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Stents; Ticlopidine | 2010 |
Late and very late stent thrombosis after polymer-based sirolimus- or paclitaxel-eluting stent implantation in real-world clinical practice.
Topics: Aspirin; Clopidogrel; Coronary Disease; Coronary Thrombosis; Drug-Eluting Stents; Humans; Paclitaxel; Platelet Aggregation Inhibitors; Polymers; Sirolimus; Ticlopidine | 2010 |
Comparison of the incidence of late stent thrombosis after implantation of different drug-eluting stents in the real world coronary heart disease patients: three-year follow-up results.
Topics: Aged; Aspirin; Clopidogrel; Coronary Disease; Coronary Thrombosis; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Ticlopidine | 2010 |
Impact of inflammatory state and metabolic control on responsiveness to dual antiplatelet therapy in type 2 diabetics after PCI: prognostic relevance of residual platelet aggregability in diabetics undergoing coronary interventions.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Biomarkers; Blood Glucose; C-Reactive Protein; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Cytokines; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Immunoassay; Inflammation; Male; Pilot Projects; Platelet Aggregation Inhibitors; Retrospective Studies; Ticlopidine; Treatment Outcome | 2010 |
Low risk of rebound events after a short course of clopidogrel in acute TIA or minor stroke.
Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Humans; Ischemic Attack, Transient; Longitudinal Studies; Male; Middle Aged; Platelet Aggregation Inhibitors; Recurrence; Retrospective Studies; Risk Assessment; Severity of Illness Index; Stroke; Ticlopidine; Time Factors; Treatment Outcome | 2010 |
[Experience of treatment of patients with myocardial infarction without raise of ST segment on ECG of high risk of cardiocomplications by method of coronary angioplasty].
Topics: Abciximab; Aged; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clopidogrel; Electrocardiography; Female; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Ticlopidine | 2010 |
Clinical pharmacology: antiplatelet therapy during surgery.
Topics: Aspirin; Blood Loss, Surgical; Clopidogrel; Humans; Perioperative Care; Platelet Aggregation Inhibitors; Postoperative Complications; Thrombosis; Ticlopidine | 2010 |
Antiplatelet therapy and percutaneous coronary intervention in patients with acute coronary syndrome and thrombocytopenia.
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Melena; Middle Aged; Neoplasms; Patient Selection; Platelet Aggregation Inhibitors; Platelet Count; Platelet Transfusion; Risk Assessment; Stents; Thrombocytopenia; Ticlopidine; Treatment Outcome | 2010 |
The causes and outcomes of inadequate implementation of existing guidelines for antiplatelet treatment in patients with acute coronary syndrome: the experience from Taiwan Acute Coronary Syndrome Descriptive Registry (T-ACCORD Registry).
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Aspirin; Chi-Square Distribution; Clopidogrel; Drug Administration Schedule; Drug Prescriptions; Drug Therapy, Combination; Drug Utilization; Female; Guideline Adherence; Hospitals; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Odds Ratio; Outcome and Process Assessment, Health Care; Patient Discharge; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Practice Patterns, Physicians'; Prospective Studies; Registries; Risk Assessment; Risk Factors; Taiwan; Ticlopidine; Time Factors; Treatment Outcome | 2010 |
[Standard therapy of acute coronary syndrome becomes easier. Dual platelet inhibition with only 1 tablet].
Topics: Acute Coronary Syndrome; Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Combinations; Germany; Guideline Adherence; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2010 |
[Interview with Prof. Uwe Zeymer, Ludwgshaven Clinic. Infarct register reveals high "loss ratios" in treatment (interview by Sonja Bohm)].
Topics: Aspirin; Clopidogrel; Drug Administration Schedule; Drug Combinations; Follow-Up Studies; Germany; Guideline Adherence; Humans; Long-Term Care; Medication Adherence; Myocardial Infarction; Platelet Aggregation Inhibitors; Registries; Survival Rate; Ticlopidine | 2010 |
Costs and consequences of clopidogrel versus aspirin for secondary prevention of ischaemic events in (high-risk) atherosclerotic patients in Sweden: a lifetime model based on the CAPRIE trial and high-risk CAPRIE subpopulations.
Topics: Aged; Aspirin; Atherosclerosis; Clopidogrel; Cost-Benefit Analysis; Female; Humans; Male; Markov Chains; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Quality-Adjusted Life Years; Secondary Prevention; Sweden; Ticlopidine | 2010 |
Thrombelastograph platelet mapping in a patient receiving antiplatelet therapy.
Topics: Aspirin; Blood Coagulation Disorders; Blood Platelets; Clopidogrel; Dose-Response Relationship, Drug; Humans; Liver Cirrhosis; Platelet Aggregation Inhibitors; Point-of-Care Systems; Thrombelastography; Ticlopidine | 2010 |
Role of dual antiplatelet therapy in symptomatic patients with established vascular disease: putting the CHARISMA trial into therapeutic perspective.
Topics: Aspirin; Clopidogrel; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Retrospective Studies; Risk; Thrombosis; Ticlopidine; Time Factors; Vascular Diseases | 2010 |
Antithrombotic therapies in patients with heart failure: hypothesis formulation from a research database.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Clopidogrel; Cohort Studies; Databases, Factual; Female; Fibrinolytic Agents; Follow-Up Studies; Heart Failure; Humans; Logistic Models; Male; Middle Aged; Platelet Aggregation Inhibitors; Proportional Hazards Models; Sex Factors; Ticlopidine; United Kingdom; Warfarin; Young Adult | 2010 |
6 steps to safer use of triple therapy. Take care when combining aspirin, Plavix, and warfarin.
Topics: Anticoagulants; Aspirin; Clopidogrel; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Health Knowledge, Attitudes, Practice; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Warfarin | 2009 |
High-dose fibrinogen concentrate for haemostatic therapy of a major trauma patient with recent clopidogrel and aspirin intake.
Topics: Aspirin; Clopidogrel; Drug Interactions; Fibrinogen; Glasgow Coma Scale; Hemorrhage; Hemostatics; Humans; Injections, Intravenous; Male; Middle Aged; Platelet Aggregation Inhibitors; Thrombelastography; Ticlopidine; Treatment Outcome; Wounds and Injuries | 2010 |
Evaluation of platelet function and pharmacological platelet inhibition in patients with myeloproliferative disorders using multiple electrode aggregometry.
Topics: Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Aspirin; Austria; Case-Control Studies; Clopidogrel; Electrodes; Female; Humans; Linear Models; Male; Middle Aged; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polycythemia Vera; Predictive Value of Tests; Reproducibility of Results; Thrombocythemia, Essential; Thrombosis; Ticlopidine; Treatment Outcome; Young Adult | 2010 |
Management of perioperative stent thrombosis in patients undergoing surgery.
Topics: Aged; Aspirin; Cardiac Surgical Procedures; Clopidogrel; Coronary Thrombosis; Humans; Male; Perioperative Period; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2010 |
Rapid change in prescribing behavior in hospitals participating in get with the guidelines-stroke after release of the management of atherothrombosis with clopidogrel in high-risk patients (MATCH) clinical trial results.
Topics: Aspirin; Brain Ischemia; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Practice Patterns, Physicians'; Prescriptions; Stroke; Ticlopidine; United States | 2010 |
Initial experience with an institutional bridging protocol for patients with recent coronary stent implantation requiring discontinuation of dual antiplatelet therapy resulting from urgent surgery.
Topics: Antithrombins; Aspirin; Blood Loss, Surgical; Clopidogrel; Coronary Thrombosis; Drug-Eluting Stents; Hirudins; Humans; Peptide Fragments; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Recombinant Proteins; Stents; Surgical Procedures, Operative; Ticlopidine; Time Factors | 2011 |
[The problems of antiaggregant therapy of patients with acute myocardial infarction. Experience with the use of clopidogrel].
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Drugs, Generic; Electrocardiography; Health Care Costs; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Secondary Prevention; Ticlopidine; Treatment Outcome | 2010 |
Recombinant activated factor VII does not reduce bleeding in rabbits treated with aspirin and clopidogrel.
Topics: Animals; Aspirin; Carotid Arteries; Clopidogrel; Disease Models, Animal; Drug Therapy, Combination; Factor VIIa; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Rabbits; Recombinant Proteins; Regional Blood Flow; Thrombosis; Ticlopidine | 2010 |
Risk of drug-eluting stent thrombosis in patients receiving proton pump inhibitors.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Chi-Square Distribution; Clopidogrel; Comorbidity; Confounding Factors, Epidemiologic; Drug Interactions; Drug Therapy, Combination; Drug-Eluting Stents; Female; Germany; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Proportional Hazards Models; Proton Pump Inhibitors; Retrospective Studies; Risk Assessment; Risk Factors; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2010 |
Duration of clopidogrel therapy with drug-eluting stents.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Disease; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2010 |
Hand surgery on anticoagulated patients: a prospective study of 121 operations.
Topics: Anticoagulants; Aspirin; Clopidogrel; Hand; Hemostasis, Surgical; Humans; International Normalized Ratio; Perioperative Care; Postoperative Hemorrhage; Thrombosis; Ticlopidine; Tourniquets; Warfarin | 2010 |
Conservative treatment of spontaneous dissection of multiple coronary arteries.
Topics: Adult; Anti-Arrhythmia Agents; Anticoagulants; Aortic Dissection; Aspirin; Clopidogrel; Coronary Aneurysm; Drug Therapy, Combination; Enoxaparin; Female; Humans; Metoprolol; Platelet Aggregation Inhibitors; Ticlopidine | 2010 |
Do not adjust the platelet count in light transmittance aggregometry when predicting thrombotic events after percutaneous coronary intervention.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Clopidogrel; Cohort Studies; Humans; Ischemia; Odds Ratio; Platelet Aggregation Inhibitors; Platelet Count; Prospective Studies; ROC Curve; Thrombosis; Ticlopidine | 2010 |
Rapid and sequential desensitization to both aspirin and clopidogrel.
Topics: Angioedema; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Hypersensitivity; Female; Humans; Middle Aged; Stents; Ticlopidine; Time Factors; Urticaria | 2010 |
[Registries of myocardial infarction in Germany. Consequences for drug therapy of patients with acute ST elevation myocardial infarction].
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Angina, Unstable; Angioplasty, Balloon, Coronary; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Clopidogrel; Coronary Restenosis; Drug Therapy, Combination; Electrocardiography; Evidence-Based Medicine; Germany; Guideline Adherence; Hospital Mortality; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Prospective Studies; Randomized Controlled Trials as Topic; Registries; Secondary Prevention; Survival Analysis; Thrombolytic Therapy; Ticlopidine; Treatment Outcome | 2010 |
Impact of inflammatory markers on platelet inhibition and cardiovascular outcome including stent thrombosis in patients with symptomatic coronary artery disease.
Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon; Aspirin; Blood Platelets; C-Reactive Protein; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Female; Humans; Inflammation; Male; Pilot Projects; Platelet Activation; Stents; Ticlopidine; Treatment Outcome | 2010 |
The influence of proton pump inhibitors on the antiplatelet potency of clopidogrel evaluated by 5 different platelet function tests.
Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Proton Pump Inhibitors; Stents; Ticlopidine | 2010 |
Transcatheter closure of patent foramen ovale (PFO) in patients with paradoxical embolism: procedural and follow-up results after implantation of the Amplatzer®-occluder device.
Topics: Aspirin; Cardiac Catheterization; Clopidogrel; Echocardiography, Transesophageal; Embolism, Paradoxical; Female; Foramen Ovale, Patent; Humans; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Risk Factors; Septal Occluder Device; Stroke; Surveys and Questionnaires; Thromboembolism; Ticlopidine | 2011 |
Response to antiplatelet treatment: from genes to outcome.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Aspirin; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Clopidogrel; Cytochrome P-450 CYP2C19; Humans; Pharmacogenetics; Piperazines; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Prasugrel Hydrochloride; Stents; Thiophenes; Ticlopidine | 2010 |
Individual variability of response and non-response to acetyl salicylic acid after cardiac surgery.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Cardiac Surgical Procedures; Clopidogrel; Dipyrone; Female; Humans; Male; Middle Aged; Pain, Postoperative; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Ticlopidine; Treatment Outcome; Young Adult | 2010 |
Cardiovascular and gastrointestinal events of three antiplatelet therapies: clopidogrel, clopidogrel plus proton-pump inhibitors, and aspirin plus proton-pump inhibitors in patients with previous gastrointestinal bleeding.
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Female; Gastrointestinal Agents; Gastrointestinal Hemorrhage; Humans; Incidence; Male; Middle Aged; Peptic Ulcer; Platelet Aggregation Inhibitors; Proportional Hazards Models; Proton Pump Inhibitors; Retrospective Studies; Risk; Taiwan; Ticlopidine; Treatment Outcome | 2011 |
Acute coronary syndromes: finding meaning in OASIS 7.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine | 2010 |
Fine-tuning therapy for acute coronary syndromes.
Topics: Acute Coronary Syndrome; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Angiography; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2010 |
Impact of platelet transfusion on hematoma expansion in patients receiving antiplatelet agents before intracerebral hemorrhage.
Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Clopidogrel; Databases, Factual; Female; Hematoma; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Transfusion; Retrospective Studies; Statistics, Nonparametric; Ticlopidine; Treatment Outcome | 2010 |
[Diagnosis of peripheral arterial occlusive disease].
Topics: Algorithms; Angioplasty, Balloon; Arterial Occlusive Diseases; Aspirin; Blood Pressure Determination; Clopidogrel; Cross-Sectional Studies; Diagnosis, Differential; Diagnostic Imaging; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2010 |
Triple antiplatelet therapy reduces ischemic events after drug-eluting stent implantation: Drug-Eluting stenting followed by Cilostazol treatment REduces Adverse Serious cardiac Events (DECREASE registry).
Topics: Aspirin; Cilostazol; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Registries; Stents; Tetrazoles; Thrombosis; Ticlopidine; Time Factors | 2010 |
Duration of clopidogrel therapy with drug-eluting stents.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Disease; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2010 |
Duration of clopidogrel therapy with drug-eluting stents.
Topics: Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Asian People; Aspirin; Clopidogrel; Coronary Disease; Cytochrome P-450 CYP2C19; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Korea; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Ticlopidine | 2010 |
Duration of clopidogrel therapy with drug-eluting stents.
Topics: Angioplasty, Balloon, Coronary; Asian People; Aspirin; Clopidogrel; Coronary Disease; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Life Style; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2010 |
CYP2C19*2 and CYP2C9*3 alleles are associated with stent thrombosis: a case-control study.
Topics: Aged; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Aspirin; Blood Vessel Prosthesis; Case-Control Studies; Clopidogrel; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Drug Therapy, Combination; Female; Genotype; Graft Occlusion, Vascular; Heterozygote; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2010 |
Risk of bleeding with single, dual, or triple therapy with warfarin, aspirin, and clopidogrel in patients with atrial fibrillation.
Topics: Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Brain Ischemia; Clopidogrel; Cohort Studies; Comorbidity; Denmark; Drug Therapy, Combination; Female; Hemorrhage; Humans; Incidence; Male; Proportional Hazards Models; Registries; Risk; Stroke; Ticlopidine; Warfarin | 2010 |
Association between inflammatory biomarkers and platelet aggregation in patients under chronic clopidogrel treatment.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Aspirin; C-Reactive Protein; Cardiovascular Diseases; Chi-Square Distribution; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Female; Fibrinogen; Germany; Humans; Inflammation Mediators; Leukocyte Count; Linear Models; Logistic Models; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Retrospective Studies; Risk Assessment; Risk Factors; Stents; Ticlopidine; Time Factors; Treatment Outcome | 2010 |
Epistaxis in patients taking oral anticoagulant and antiplatelet medication: prospective cohort study.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Clopidogrel; Drug Therapy, Combination; Epistaxis; Hemostatic Techniques; Humans; International Normalized Ratio; Length of Stay; Middle Aged; Platelet Aggregation Inhibitors; Prevalence; Prospective Studies; Ticlopidine; Warfarin; Young Adult | 2011 |
Genetic variability in response to clopidogrel therapy: clinical implications.
Topics: Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Female; Graft Occlusion, Vascular; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine | 2010 |
Clinical predictors of dual aspirin and clopidogrel poor responsiveness in stable cardiovascular patients from the ADRIE study.
Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prognosis; Purinergic P2Y Receptor Antagonists; Ticlopidine | 2010 |
Does current oral antiplatelet agent or subtherapeutic anticoagulation use have an effect on tissue-plasminogen-activator-mediated recanalization rate in patients with acute ischemic stroke?
Topics: Administration, Oral; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Fibrinolytic Agents; Humans; Injections, Intravenous; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Retrospective Studies; Stroke; Thrombolytic Therapy; Ticlopidine; Tissue Plasminogen Activator; Treatment Outcome; Warfarin | 2010 |
Vincristine-ticlopidine-aspirin: an effective therapy in children with Kasabach-Merritt phenomenon associated with vascular tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Aspirin; Disseminated Intravascular Coagulation; Female; Hemangioma, Capillary; Humans; Infant; Kasabach-Merritt Syndrome; Ticlopidine; Treatment Outcome; Vascular Neoplasms; Vincristine | 2010 |
Intracoronary shear-related up-regulation of platelet P-selectin and platelet-monocyte aggregation despite the use of aspirin and clopidogrel.
Topics: Aged; Aspirin; Blood Platelets; CD11b Antigen; Clopidogrel; Coronary Artery Disease; Coronary Stenosis; Flow Cytometry; Humans; Leukocytes; Monocytes; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; Up-Regulation | 2011 |
Outcomes related to antiplatelet or anticoagulation use in patients undergoing carotid endarterectomy.
Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Chi-Square Distribution; Clopidogrel; Endarterectomy, Carotid; Female; Hematoma; Humans; Male; Middle Aged; Minnesota; Myocardial Infarction; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Retrospective Studies; Risk Assessment; Risk Factors; Stroke; Ticlopidine; Time Factors; Treatment Outcome; Warfarin | 2011 |
Determination of the prevalence of aspirin and clopidogrel resistances in patients with coronary artery disease by using various platelet-function tests.
Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Artery Disease; Drug Resistance; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Tetrazoles; Ticlopidine | 2010 |
[Does dual antiplatelet therapy always require gastroprotection? Tailored medical therapy should prevail over the generalized prescription of proton pump inhibitors in patients on dual antiplatelet therapy].
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Electrocardiography; Follow-Up Studies; Gastrointestinal Hemorrhage; Humans; Myocardial Infarction; Myocardial Revascularization; Odds Ratio; Peptic Ulcer; Platelet Aggregation Inhibitors; Prognosis; Proton Pump Inhibitors; Pyridines; Randomized Controlled Trials as Topic; Ticlopidine; Time Factors | 2010 |
Incidence of hemorrhagic complications after intravitreal bevacizumab (avastin) or ranibizumab (lucentis) injections on systemically anticoagulated patients.
Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticoagulants; Aspirin; Bevacizumab; Choroidal Neovascularization; Clopidogrel; Eye Hemorrhage; Female; Humans; Incidence; Intravitreal Injections; Macular Degeneration; Male; Middle Aged; Platelet Aggregation Inhibitors; Ranibizumab; Retrospective Studies; Risk Factors; Ticlopidine; Vascular Endothelial Growth Factor A; Warfarin | 2010 |
No inconsistent trial assessments by NICE and IQWiG: different assessment goals may lead to different assessment results regarding subgroup analyses.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; England; Evidence-Based Medicine; Germany; Humans; Prescription Drugs; Randomized Controlled Trials as Topic; Research Design; Ticlopidine | 2010 |
Acute myocardial infarction and renal infarction in a bodybuilder using anabolic steroids.
Topics: Adult; Anabolic Agents; Angiography; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coronary Angiography; Drug Therapy, Combination; Enoxaparin; Fibrinolytic Agents; Humans; Infarction; Kidney; Male; Methenolone; Myocardial Infarction; Oxymetholone; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine; Tomography, X-Ray Computed; Ultrasonography; Weight Lifting | 2010 |
Three-month dual antiplatelet therapy after implantation of zotarolimus-eluting stents: the DATE (Duration of Dual Antiplatelet Therapy AfterImplantation of Endeavor Stent) registry.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Agents; Chi-Square Distribution; Clopidogrel; Coronary Angiography; Coronary Stenosis; Disease-Free Survival; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Feasibility Studies; Female; Humans; Kaplan-Meier Estimate; Logistic Models; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Propensity Score; Proportional Hazards Models; Prospective Studies; Prosthesis Design; Registries; Republic of Korea; Risk Assessment; Risk Factors; Sirolimus; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2010 |
Platelet aggregation pathway.
Topics: Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Cyclooxygenase 1; Cytochrome P-450 CYP2C19; Drug Resistance; Humans; Integrin beta3; Metabolic Networks and Pathways; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoprotein IIb; Polymorphism, Single Nucleotide; Ticlopidine | 2011 |
Impact of concomitant treatment with proton pump inhibitors and clopidogrel on clinical outcome in patients after coronary stent implantation.
Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Chi-Square Distribution; Clopidogrel; Drug Therapy, Combination; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Patient Readmission; Platelet Aggregation Inhibitors; Propensity Score; Proportional Hazards Models; Proton Pump Inhibitors; Registries; Retrospective Studies; Risk Assessment; Risk Factors; Stents; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2010 |
Clopidogrel discontinuation and platelet reactivity following coronary stenting.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Arachidonic Acid; Aspirin; Clopidogrel; Collagen; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Epinephrine; Female; Humans; Ireland; Male; Middle Aged; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prospective Studies; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2011 |
Tranexamic acid partially improves platelet function in patients treated with dual antiplatelet therapy.
Topics: Aged; Antifibrinolytic Agents; Aspirin; Clopidogrel; Coronary Artery Bypass; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Ticlopidine; Tranexamic Acid | 2011 |
Low risk of intracranial and systemic hemorrhages in patients on dual antiplatelet treatment beyond 1 month following neuroendovascular angioplasty and/or stent placement.
Topics: Angioplasty; Aspirin; Blood Vessel Prosthesis; Clopidogrel; Combined Modality Therapy; Comorbidity; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Intracranial Hemorrhages; Male; Middle Aged; Minnesota; Platelet Aggregation Inhibitors; Prevalence; Radiography; Risk Assessment; Risk Factors; Stents; Survival Analysis; Survival Rate; Ticlopidine; Treatment Outcome | 2012 |
Frequency of left ventricular thrombus in patients with anterior wall acute myocardial infarction treated with percutaneous coronary intervention and dual antiplatelet therapy.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Chi-Square Distribution; Clopidogrel; Combined Modality Therapy; Coronary Thrombosis; Creatine Kinase; Echocardiography; Female; Heart Ventricles; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Prevalence; Statistics, Nonparametric; Stents; Ticlopidine; Tomography, Emission-Computed, Single-Photon | 2010 |
Peak cardiac troponin-T level, scintigraphic myocardial infarct size and one-year prognosis in patients undergoing primary percutaneous coronary intervention for acute myocardial infarction.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Biomarkers; Clopidogrel; Combined Modality Therapy; Creatine Kinase, MB Form; Female; Germany; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Perfusion Imaging; Platelet Aggregation Inhibitors; Prognosis; Prospective Studies; Radiopharmaceuticals; Registries; Technetium Tc 99m Sestamibi; Ticlopidine; Tomography, Emission-Computed, Single-Photon; Troponin T | 2010 |
Resistance to aspirin and clopidogrel therapy.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2011 |
[Efficacy of stents coated with antibody against CD105 on preventing restenosis and thrombosis in minipigs].
Topics: Animals; Antibodies; Antigens, CD; Aspirin; Clopidogrel; Coronary Restenosis; Endothelial Cells; Neointima; Stents; Swine; Swine, Miniature; Thrombosis; Ticlopidine | 2010 |
Role of intramural platelet thrombus in the pathogenesis of wall rupture and intra-ventricular thrombosis following acute myocardial infarction.
Topics: Animals; Aspirin; Blood Platelets; Clopidogrel; Disease Models, Animal; Hemodynamics; Inflammation; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Myocardial Infarction; Platelet Aggregation Inhibitors; Telemetry; Thrombosis; Ticlopidine; Time Factors; Ventricular Septal Rupture | 2011 |
Paradoxical embolism.
Topics: Aged; Aspirin; Clopidogrel; Dipyridamole; Dyspnea; Echocardiography, Transesophageal; Embolism, Paradoxical; Female; Heart Atria; Humans; Platelet Aggregation Inhibitors; Secondary Prevention; Stroke; Ticlopidine; Tomography, X-Ray Computed; Treatment Outcome; Walking | 2010 |
Emerging oral antiplatelet therapies for acute coronary syndromes.
Topics: Acute Coronary Syndrome; Adenosine; Administration, Oral; Aspirin; Cardiology; Clopidogrel; Drug Therapy, Combination; Emergency Medicine; Hemorrhage; Hospitalists; Humans; Imines; Lactones; Patient Selection; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Purinergic P2Y Receptor Antagonists; Pyridines; Receptor, PAR-1; Risk Factors; Ticagrelor; Ticlopidine; Treatment Outcome | 2010 |
Clinical impact of enhanced inhibition of P2Y12-mediated platelet aggregation in patients with ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention.
Topics: Adenosine; Administration, Oral; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Electrocardiography; Humans; Myocardial Infarction; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Proportional Hazards Models; Purinergic P2Y Receptor Antagonists; Risk Factors; Thiophenes; Ticagrelor; Ticlopidine; Treatment Outcome | 2010 |
Influence of antiplatelet drugs in the pathogenesis of experimental periodontitis and periodontal repair in rats.
Topics: Alveolar Bone Loss; Animals; Aspirin; Blood Platelets; Bone Density; Bone Regeneration; Clopidogrel; Inflammation Mediators; Intercellular Signaling Peptides and Proteins; Interleukin-6; Leukocytes; Male; Mandibular Diseases; Periodontal Attachment Loss; Periodontitis; Periodontium; Platelet Activation; Platelet Aggregation Inhibitors; Random Allocation; Rats; Rats, Sprague-Dawley; Thromboxane A2; Ticlopidine; Time Factors; Tumor Necrosis Factor-alpha; Wound Healing; X-Ray Microtomography | 2011 |
Nontraumatic bilateral subdural hematoma caused by antiaggregation therapy: case report and review of the literature.
Topics: Adenosine Diphosphate; Aspirin; Clopidogrel; Female; Hematoma, Subdural; Humans; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Radiography; Ticlopidine | 2010 |
National estimates of emergency department visits for hemorrhage-related adverse events from clopidogrel plus aspirin and from warfarin.
Topics: Acute Disease; Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Clopidogrel; Drug Therapy, Combination; Emergency Service, Hospital; Female; Health Care Surveys; Hemorrhage; Hospitalization; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Sex Distribution; Ticlopidine; United States; Warfarin; Young Adult | 2010 |
[Between thrombosis and bleeding - a case of paroxysmal nocturnal hemoglobinuria].
Topics: Aged; Anticoagulants; Aspirin; Cerebral Hemorrhage; Clopidogrel; Coronary Thrombosis; Drug Therapy, Combination; Fatal Outcome; Female; Hemoglobinuria, Paroxysmal; Heparin; Heparin, Low-Molecular-Weight; Humans; Phenprocoumon; Platelet Aggregation Inhibitors; Ticlopidine; Tomography, X-Ray Computed | 2010 |
Antiplatelet therapy effectively reduces plasma plasminogen activator inhibitor-1 levels.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Brain Ischemia; Case-Control Studies; Clopidogrel; Down-Regulation; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Plasminogen Activator Inhibitor 1; Platelet Aggregation; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Time Factors; Treatment Outcome | 2011 |
Ischaemic stroke--prevention is better than cure.
Topics: Adult; Age Factors; Aged; Anticoagulants; Antihypertensive Agents; Aspirin; Atrial Fibrillation; Blood Glucose; Cholesterol; Clopidogrel; Confidence Intervals; Decompression, Surgical; Endarterectomy, Carotid; Fibrinolytic Agents; Glycated Hemoglobin; Humans; Incidence; Middle Aged; Platelet Aggregation Inhibitors; Prevalence; Randomized Controlled Trials as Topic; Recurrence; Risk Factors; Smoking Cessation; Stroke; Ticlopidine | 2010 |
Delayed intracranial hemorrhage associated with antiplatelet therapy in stent-assisted coil embolized cerebral aneurysms.
Topics: Adult; Aged; Aspirin; Cerebral Hemorrhage; Clopidogrel; Cohort Studies; Embolization, Therapeutic; Female; Follow-Up Studies; Humans; Imaging, Three-Dimensional; Intracranial Aneurysm; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Stents; Ticlopidine; Tomography Scanners, X-Ray Computed | 2011 |
Hybrid revascularization, comprising coronary artery bypass graft with exclusive arterial conduits followed by early drug-eluting stent implantation, in multivessel coronary artery disease.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Case-Control Studies; Chi-Square Distribution; Clopidogrel; Combined Modality Therapy; Coronary Artery Bypass; Coronary Artery Bypass, Off-Pump; Coronary Artery Disease; Drug-Eluting Stents; Feasibility Studies; Female; France; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Prospective Studies; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome | 2010 |
Combination of low-dose aspirin and thienopyridine exacerbates small bowel injury.
Topics: Aged; Aged, 80 and over; Aspirin; Capsule Endoscopy; Clopidogrel; Drug Therapy, Combination; Female; Fibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Intestinal Mucosa; Intestine, Small; Male; Middle Aged; Pyridines; Retrospective Studies; Ticlopidine; Ulcer; Warfarin | 2011 |
[Efficacy and safety of concomitant use of rabeprazole during dual-antiplatelet therapy with clopidogrel and aspirin after drug-eluting stent implantation: a retrospective cohort study].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Cohort Studies; Coronary Thrombosis; Cytochrome P-450 CYP2C19; Drug Interactions; Drug-Eluting Stents; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Proton Pump Inhibitors; Rabeprazole; Retrospective Studies; Ticlopidine; Treatment Outcome | 2010 |
What is the optimal duration of triple anti-platelet therapy in patients with acute myocardial infarction undergoing drug-eluting stent implantation?
Topics: Aspirin; Cilostazol; Clopidogrel; Coronary Thrombosis; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Recurrence; Retrospective Studies; Tetrazoles; Ticlopidine; Time Factors | 2011 |
Antiplatelet and antithrombotic treatment after primary percutaneous coronary intervention: balancing safety and efficacy.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Administration Schedule; Fibrinolytic Agents; Hemorrhage; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Risk Assessment; Safety; Secondary Prevention; Thiophenes; Ticlopidine; Treatment Outcome; Warfarin | 2010 |
Dosing of clopidogrel and aspirin in acute coronary syndromes.
Topics: Acute Coronary Syndrome; Algorithms; Angina, Unstable; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine | 2010 |
Dosing of clopidogrel and aspirin in acute coronary syndromes.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Drug Antagonism; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine | 2010 |
Dosing of clopidogrel and aspirin in acute coronary syndromes.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Combined Modality Therapy; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2010 |
Clinical and angiographic outcomes with sirolimus-eluting stent for coronary bifurcation lesions. The J-PMS study.
Topics: Angioplasty; Aspirin; Calcinosis; Coronary Angiography; Coronary Restenosis; Coronary Stenosis; Coronary Thrombosis; Coronary Vessels; Drug-Eluting Stents; Follow-Up Studies; Graft Occlusion, Vascular; Humans; Japan; Myocardial Infarction; Platelet Aggregation Inhibitors; Product Surveillance, Postmarketing; Sirolimus; Survival Analysis; Thrombophilia; Ticlopidine; Treatment Outcome | 2011 |
Measurement of platelet reactivity of patients with cardiovascular disease on-treatment with acetyl salicylic acid: a prospective study.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Aspirin; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Drug Resistance; Drug Therapy, Combination; Female; Humans; Logistic Models; Male; Medication Adherence; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Risk Assessment; Risk Factors; Sex Factors; Ticlopidine; Treatment Outcome | 2011 |
Frequency and location of yellow and disrupted coronary plaques in patients as detected by angioscopy.
Topics: Acute Coronary Syndrome; Aged; Angioscopy; Aspirin; Clopidogrel; Coronary Artery Disease; Disease Progression; Female; Humans; Incidence; Male; Middle Aged; Myocardial Infarction; Plaque, Atherosclerotic; Platelet Aggregation Inhibitors; Retrospective Studies; Severity of Illness Index; Ticlopidine | 2011 |
Beware of being caught on the rebound.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2011 |
[Current status of medical therapy of chronic stable angina pectoris in mainland of China: the second survey].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angina Pectoris; Angiotensin Receptor Antagonists; Aspirin; China; Chronic Disease; Clopidogrel; Cross-Sectional Studies; Female; Guideline Adherence; Health Care Surveys; Humans; Male; Middle Aged; Surveys and Questionnaires; Ticlopidine | 2010 |
Catapulting clopidogrel pharmacogenomics forward.
Topics: Amino Acid Substitution; Aryldialkylphosphatase; Aspirin; Blood Platelets; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Stents; Thrombosis; Ticlopidine | 2011 |
Behind the paper: stepping up to the antiplatelet.
Topics: Amino Acid Sequence; Aryldialkylphosphatase; Aspirin; Clopidogrel; Coronary Thrombosis; Cytochrome P-450 Enzyme System; Drug Tolerance; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine | 2011 |
Lack of correlation between platelet reactivity and glycaemic control in type 2 diabetes mellitus patients treated with aspirin and clopidogrel.
Topics: Aged; Aged, 80 and over; Angina Pectoris; Aspirin; Blood Glucose; Blood Platelets; Clopidogrel; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Glycemic Index; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine; Time Factors | 2011 |
Simultaneous determination of clopidogrel and aspirin by RP-HPLC from bulk material and dosage formulations using multivariate calibration technique.
Topics: Aspirin; Calibration; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Clopidogrel; Linear Models; Multivariate Analysis; Reproducibility of Results; Sensitivity and Specificity; Ticlopidine | 2011 |
[Renal artery stenosis: angioplasty or drug treatment?].
Topics: Aged; Angioplasty; Anticoagulants; Antihypertensive Agents; Aspirin; Blood Pressure; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Combined Modality Therapy; Creatinine; Diagnostic Imaging; Female; Follow-Up Studies; Germany; Glomerular Filtration Rate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Renovascular; Male; Middle Aged; Renal Artery Obstruction; Renal Dialysis; Retrospective Studies; Risk Factors; Survival Rate; Ticlopidine | 2011 |
"Short" thrombelastography as a test of platelet reactivity in response to antiplatelet therapy: validation and reproducibility.
Topics: Aspirin; Blood Platelets; Clopidogrel; Humans; Individuality; Platelet Aggregation; Platelet Aggregation Inhibitors; Reproducibility of Results; Thrombelastography; Ticlopidine | 2011 |
Clinical follow-up 3 years after everolimus- and paclitaxel-eluting stents: a pooled analysis from the SPIRIT II (A Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System in the Treatment of Patients With De Novo Native Coronary Arte
Topics: Angioplasty, Balloon, Coronary; Antineoplastic Agents, Phytogenic; Aspirin; Clopidogrel; Confidence Intervals; Coronary Artery Disease; Drug-Eluting Stents; Everolimus; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Kaplan-Meier Estimate; Logistic Models; Male; Middle Aged; Paclitaxel; Platelet Aggregation Inhibitors; Proportional Hazards Models; Randomized Controlled Trials as Topic; Risk; Risk Reduction Behavior; Sirolimus; Ticlopidine; Time Factors | 2010 |
[Antiplatelet agents in acute coronary syndromes. Data from the main clinical trials].
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Clinical Trials as Topic; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Ticagrelor; Ticlopidine | 2010 |
[Antiplatelet agents and diabetes mellitus].
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Diabetes Mellitus, Type 2; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2010 |
Antiplatelet drugs in the elderly: prescriptions often inappropriate and reduced tolerance by associated diseases and drugs.
Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Female; France; Hemorrhage; Humans; Male; Off-Label Use; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Practice Patterns, Physicians'; Prospective Studies; Risk Factors; Ticlopidine | 2012 |
Overview of the 2010 Food and Drug Administration Cardiovascular and Renal Drugs Advisory Committee meeting regarding ticagrelor.
Topics: Acute Coronary Syndrome; Adenosine; Advisory Committees; Aspirin; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Clopidogrel; Drug Approval; Humans; Multicenter Studies as Topic; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Randomized Controlled Trials as Topic; Thrombosis; Ticagrelor; Ticlopidine; United States | 2011 |
Endothelial progenitor cell capturing stent and short dual antiplatelet therapy in patients on chronic anti-vitamin k regimen undergoing percutaneous coronary interventions: long-term outcomes of a single centre registry.
Topics: Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coated Materials, Biocompatible; Coronary Disease; Disease-Free Survival; Endothelial Cells; Female; Humans; Male; Platelet Aggregation Inhibitors; Stem Cells; Stents; Ticlopidine; Vitamin K | 2011 |
Double-dose clopidogrel in patients undergoing PCI for ACS.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine | 2011 |
Double-dose clopidogrel in patients undergoing PCI for ACS.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Humans; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine | 2011 |
Resistance to anti-platelet agents.
Topics: Adenosine; Aspirin; Clopidogrel; Drug Resistance; Humans; Piperazines; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Thiophenes; Ticagrelor; Ticlopidine | 2011 |
Proton pump inhibitors in patients treated with aspirin and clopidogrel after acute coronary syndrome.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine | 2010 |
Low responsiveness to clopidogrel increases risk among CKD patients undergoing coronary intervention.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Chronic Disease; Clopidogrel; Cohort Studies; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Hemorrhage; Humans; Kidney Diseases; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Ticlopidine; Treatment Outcome | 2011 |
Optimal antithrombotic therapy in patients receiving long-term oral anticoagulation requiring percutaneous coronary intervention: "triple therapy" or "triple threat".
Topics: Administration, Oral; Anticoagulants; Aspirin; Clopidogrel; Drug Therapy, Combination; Heart Diseases; Humans; Meta-Analysis as Topic; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Stents; Stroke; Thromboembolism; Ticlopidine; Warfarin | 2011 |
Antiplatelet agents do not impact the hospital course in patients with gastrointestinal bleeding.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Cohort Studies; Dizziness; Female; Gastrointestinal Hemorrhage; Hospitalization; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Risk Factors; Ticlopidine; Treatment Outcome; Young Adult | 2011 |
TIAs - management in general practice.
Topics: Anticoagulants; Antihypertensive Agents; Aspirin; Atorvastatin; Clopidogrel; Dipyridamole; Dopamine Antagonists; General Practitioners; Heptanoic Acids; Humans; Hypolipidemic Agents; Ischemic Attack, Transient; Perindopril; Platelet Aggregation Inhibitors; Primary Health Care; Prochlorperazine; Pyrroles; Ticlopidine; Vasodilator Agents; Warfarin | 2010 |
Endoscopic resection of bladder cancer in patients receiving double platelet antiaggregant therapy.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiac Surgical Procedures; Clopidogrel; Coronary Restenosis; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Urinary Bladder Neoplasms | 2011 |
Conversation with an expert. Plavix: what you need to know.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Administration Schedule; Drug Costs; Drug Interactions; Drug Therapy, Combination; Drug-Eluting Stents; Health Knowledge, Attitudes, Practice; Humans; Patient Education as Topic; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine | 2011 |
Recurrent episodes of very late stent thrombosis in a patient with aspirin hypersensitivity, stent fracture and malapposition.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Occlusion; Coronary Thrombosis; Drug Hypersensitivity; Drug-Eluting Stents; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prosthesis Failure; Recurrence; Ticlopidine; Time Factors; Tomography, Optical Coherence | 2011 |
The effect of clopidogrel and aspirin on blood loss in hip fracture surgery.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Blood Transfusion; Clopidogrel; Drug Therapy, Combination; Female; Hip Fractures; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Preoperative Care; Ticlopidine; Time Factors; Treatment Outcome | 2011 |
Treatment patterns in acute coronary syndrome patients in the United Kingdom undergoing PCI.
Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Thrombosis; Female; Humans; Length of Stay; Male; Middle Aged; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Prospective Studies; Registries; Retreatment; Stents; Ticlopidine; United Kingdom | 2011 |
Immortal person-time bias in observational studies in cardiac surgery.
Topics: Aspirin; Bias; Clopidogrel; Coronary Artery Bypass; Data Interpretation, Statistical; Drug Therapy, Combination; Hemorrhage; Hospital Mortality; Humans; Platelet Aggregation Inhibitors; Postoperative Complications; Research Design; Risk Assessment; Risk Factors; Ticlopidine; Treatment Outcome | 2011 |
Effects of antithrombogenic agents on microvenous anastomoses in a rat model.
Topics: Anastomosis, Surgical; Animals; Aspirin; Clopidogrel; Femoral Vein; Ketorolac Tromethamine; Microcirculation; Models, Animal; Platelet Aggregation Inhibitors; Random Allocation; Rats; Ticlopidine; Time Factors; Vascular Patency; Venous Thrombosis | 2011 |
Risk of upper gastrointestinal bleeding with low-dose acetylsalicylic acid alone and in combination with clopidogrel and other medications.
Topics: Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Case-Control Studies; Clopidogrel; Cohort Studies; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk; Ticlopidine; United Kingdom | 2011 |
Endovascular treatment using predominantly stent-assisted coil embolization and antiplatelet and anticoagulation management of ruptured blood blister-like aneurysms.
Topics: Adult; Aged; Aneurysm, Ruptured; Anticoagulants; Aspirin; Cerebral Angiography; Clopidogrel; Combined Modality Therapy; Embolization, Therapeutic; Female; Follow-Up Studies; Heparin; Humans; Intracranial Aneurysm; Intracranial Thrombosis; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Secondary Prevention; Stents; Ticlopidine | 2011 |
Clopidogrel and modified-release dipyridamole for the prevention of occlusive vascular events (NICE technology appraisal guidance 90).
Topics: Aspirin; Clopidogrel; Constriction, Pathologic; Delayed-Action Preparations; Dipyridamole; Drugs, Generic; Humans; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Ticlopidine; Vascular Diseases | 2011 |
Treatment of GERD and proton pump inhibitor use in the elderly: practical approaches and frequently asked questions.
Topics: Adenocarcinoma; Adult; Age Distribution; Age Factors; Aged; Aged, 80 and over; Aspirin; Barrett Esophagus; Clopidogrel; Drug Interactions; Drug Prescriptions; Esophageal Neoplasms; Esophagitis; Esophagoscopy; Gastroesophageal Reflux; Gastroscopy; Heartburn; Hip Fractures; Humans; Intestinal Absorption; Middle Aged; Obesity; Odds Ratio; Platelet Aggregation Inhibitors; Population Surveillance; Prevalence; Proton Pump Inhibitors; Ticlopidine; Vitamin B 12 | 2011 |
What is the best antiplatelet agent for prevention of recurrent stroke in Pakistani patients? Do combinations offer significant advantages in the South Asian context?
Topics: Asian People; Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Evidence-Based Medicine; Follow-Up Studies; Humans; Pakistan; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Secondary Prevention; Stroke; Ticlopidine; Treatment Outcome | 2010 |
What is the best first agent to give to a patient with acute ischaemic stroke? Aspirin, heparin, clopidogrel, cilostazol or dipyridamole?
Topics: Aspirin; Brain Ischemia; Cilostazol; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Evidence-Based Medicine; Fibrinolytic Agents; Heparin; Humans; Platelet Aggregation Inhibitors; Stroke; Tetrazoles; Ticlopidine | 2010 |
Relapsed spontaneous spinal epidural hematoma associated with aspirin and clopidogrel.
Topics: Aspirin; Clopidogrel; Hematoma, Epidural, Spinal; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neurologic Examination; Platelet Aggregation Inhibitors; Recurrence; Spine; Stroke; Ticlopidine; Tomography, X-Ray Computed | 2011 |
Antiplatelet pretreatment does not increase hematoma volume in experimental intracerebral hemorrhage.
Topics: Animals; Aspirin; Blood Coagulation; Cerebral Hemorrhage; Clopidogrel; Hematoma; Mice; Plasma Cells; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Failure | 2011 |
Oral antiplatelet therapy for atherothrombotic disease: current evidence and new directions.
Topics: Acute Coronary Syndrome; Adenosine; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Humans; Lactones; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Pyridines; Quinazolinones; Randomized Controlled Trials as Topic; Receptor, PAR-1; Sulfonamides; Ticagrelor; Ticlopidine | 2011 |
The relation between CYP2C19 genotype and phenotype in stented patients on maintenance dual antiplatelet therapy.
Topics: Aged; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Genotype; Humans; Linkage Disequilibrium; Male; Middle Aged; Phenotype; Platelet Aggregation; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2011 |
Significance of cardiocoronary pathology in acute stroke.
Topics: Aspirin; Clopidogrel; Coronary Disease; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2011 |
Antiplatelet and anticoagulation therapy in vitreoretinal surgery.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Case-Control Studies; Child; Clopidogrel; Contraindications; Eye Hemorrhage; Female; Humans; Incidence; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Retrospective Studies; Risk Factors; Ticlopidine; Vitreoretinal Surgery; Warfarin | 2011 |
Effective management of acute coronary thrombosis in a young woman with lupus using aggressive medical therapy.
Topics: Adult; Aspirin; Clopidogrel; Coronary Thrombosis; Eptifibatide; Female; Fibrinolytic Agents; Heparin; Humans; Lupus Erythematosus, Systemic; Peptides; Platelet Aggregation Inhibitors; Ticlopidine | 2011 |
[Beyond coronary artery disease: interventional approach to carotid occlusive disease].
Topics: Aged; Aged, 80 and over; Angioplasty; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carotid Artery, Internal; Carotid Stenosis; Female; Fibrinolytic Agents; Follow-Up Studies; Humans; Magnetic Resonance Angiography; Male; Middle Aged; Platelet Aggregation Inhibitors; Recurrence; Retrospective Studies; Stents; Ticlopidine; Time Factors; Treatment Outcome; Ultrasonography, Doppler | 2010 |
Optimal timing of anticoagulation pre- and post-colonoscopy with polypectomy.
Topics: Anticoagulants; Aspirin; Clopidogrel; Colonic Polyps; Colonoscopy; Female; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibitors; Postoperative Period; Retrospective Studies; Ticlopidine; Warfarin | 2011 |
Peri-operative management of antiplatelet therapy in patients with coronary artery disease: joint position paper by members of the working group on Perioperative Haemostasis of the Society on Thrombosis and Haemostasis Research (GTH), the working group on
Topics: Aspirin; Blood Loss, Surgical; Cardiovascular Surgical Procedures; Clopidogrel; Contraindications; Coronary Artery Disease; Drug-Eluting Stents; Evidence-Based Medicine; Hemostasis, Surgical; Humans; Perioperative Care; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Precision Medicine; Ticlopidine | 2011 |
Acute upper gastrointestinal hemorrhage in an elderly woman taking aspirin and clopidogrel.
Topics: Aged; Aspirin; Clopidogrel; Female; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2011 |
A case of subacute thrombosis associated with clopidogrel resistance after implantation of a zotarolimus-eluting stent.
Topics: Aged; Angioplasty, Balloon, Coronary; Anterior Wall Myocardial Infarction; Aryl Hydrocarbon Hydroxylases; Aspirin; Cardiovascular Agents; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug Resistance; Drug-Eluting Stents; Female; Genotype; Humans; Phenotype; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Prosthesis Design; Sirolimus; Thrombectomy; Thrombosis; Ticlopidine; Treatment Outcome; Ultrasonography, Interventional | 2012 |
Protect your heart during dental work. Don't stop taking aspirin, Plavix, or any other antiplatelet before dental work without asking your cardiologist.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Dental Care for Chronically Ill; Heart Diseases; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2011 |
Use of the oral platelet inhibitors dipyridamole and acetylsalicylic acid is associated with increased risk of fracture.
Topics: Acute Coronary Syndrome; Adult; Aged; Aspirin; Case-Control Studies; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Female; Fractures, Bone; Humans; Male; Middle Aged; Osteoporosis; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Risk; Ticlopidine | 2012 |
Atrial fibrillation, is warfarin the only option for stroke prevention?
Topics: Angiotensin II Type 1 Receptor Blockers; Anticoagulants; Aspirin; Atrial Fibrillation; Biphenyl Compounds; Cerebral Hemorrhage; Clopidogrel; Evidence-Based Medicine; Follow-Up Studies; Humans; Hypertension; Irbesartan; Platelet Aggregation Inhibitors; Stroke; Tetrazoles; Ticlopidine; Treatment Outcome; Warfarin | 2011 |
Left main stent thrombosis complicated by eptifibatide-induced acute thrombocytopenia.
Topics: Acute Disease; Angioplasty, Balloon, Coronary; Aspirin; Cardiac Catheterization; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Drug Therapy, Combination; Electrocardiography; Eptifibatide; Heparin; Humans; Male; Middle Aged; Peptides; Platelet Aggregation Inhibitors; Platelet Count; Stents; Thrombectomy; Thrombocytopenia; Thrombosis; Ticlopidine; Treatment Outcome | 2011 |
[Multiple arterial thrombosis and resistance to conventional antiaggregation].
Topics: Aged; Angiography; Aspirin; Clopidogrel; Coronary Thrombosis; Drug Resistance; Electrocardiography; Female; Femoral Artery; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Thrombosis; Ticlopidine | 2011 |
Increased platelet turnover in patients with previous definite stent thrombosis.
Topics: Aspirin; Blood Platelets; Coronary Thrombosis; Female; Humans; Male; Ticlopidine | 2011 |
Age-related differences in antithrombotic therapy, success rate and in-hospital mortality in patients undergoing percutaneous coronary intervention: results of the quality control registry of the Arbeitsgemeinschaft Leitende Kardiologische Krankenhausärzt
Topics: Acute Coronary Syndrome; Age Factors; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Comorbidity; Female; Fibrinolytic Agents; Germany; Hospital Mortality; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Registries; Ticlopidine; Treatment Outcome | 2011 |
[Preoperative analysis of platelet aggregability in carotid surgery].
Topics: Aged; Aged, 80 and over; Aspirin; Carotid Arteries; Clopidogrel; Endarterectomy, Carotid; Female; Humans; Intraoperative Complications; Ischemia; Male; Middle Aged; Perioperative Period; Platelet Aggregation; Platelet Aggregation Inhibitors; Postoperative Complications; Retrospective Studies; Stents; Ticlopidine | 2011 |
Complications of cutaneous surgery in patients taking clopidogrel-containing anticoagulation.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Clopidogrel; Dermatologic Surgical Procedures; Female; Humans; Male; Middle Aged; Mohs Surgery; Platelet Aggregation Inhibitors; Postoperative Complications; Postoperative Hemorrhage; Ticlopidine; Warfarin | 2011 |
A postal survey of UK practice on discontinuation of anticoagulant/antithrombotics therapy before minor cutaneous surgery of the head and neck.
Topics: Ambulatory Surgical Procedures; Anticoagulants; Aspirin; Cervicoplasty; Clopidogrel; Drug Administration Schedule; Fibrinolytic Agents; Humans; Practice Patterns, Physicians'; Preoperative Care; Surveys and Questionnaires; Ticlopidine; United Kingdom; Warfarin | 2011 |
How do we manage patients treated with antithrombotic therapy in the perioperative interval.
Topics: Anticoagulants; Antifibrinolytic Agents; Antithrombins; Aspirin; Blood Loss, Surgical; Blood Transfusion; Clopidogrel; Coagulants; Factor Xa Inhibitors; Fibrinolytic Agents; Hemostasis, Surgical; Heparin; Humans; Perioperative Care; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Risk Assessment; Ticlopidine; Vitamin K; Warfarin | 2011 |
Efficacy and safety of clopidogrel after PCI with stenting in patients on oral anticoagulants with acute coronary syndrome.
Topics: Acute Coronary Syndrome; Administration, Oral; Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coronary Care Units; Drug Administration Schedule; Drug Therapy, Combination; Female; Hemorrhage; Humans; Logistic Models; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Propensity Score; Proportional Hazards Models; Registries; Risk Assessment; Risk Factors; Stents; Sweden; Ticlopidine; Time Factors; Treatment Outcome | 2011 |
Dual antiplatelet therapy and the risk of bleeding.
Topics: Aspirin; Atrial Fibrillation; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Risk Assessment; Risk Factors; Thrombosis; Ticlopidine; Warfarin | 2011 |
[Does combination therapy of aspirin plus antiplatelet therapy increase the risk of upper gastrointestinal hemorrhage?].
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Endoscopy, Gastrointestinal; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine | 2011 |
[The effect of aspirin alone or aspirin plus additional antiplatelets therapy on upper gastrointestinal hemorrhage].
Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Endoscopy, Gastrointestinal; Female; Gastrointestinal Hemorrhage; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Peptic Ulcer; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Ticlopidine | 2011 |
The use of contrast echo to clear the left atrial appendage.
Topics: Aspirin; Atrial Appendage; Clopidogrel; Contrast Media; Drug Therapy, Combination; Echocardiography; Echocardiography, Transesophageal; Fluorocarbons; Heart Atria; Heart Diseases; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine | 2011 |
No association of paraoxonase-1 Q192R genotypes with platelet response to clopidogrel and risk of stent thrombosis after coronary stenting.
Topics: Aged; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Aryldialkylphosphatase; Aspirin; Clopidogrel; Coronary Disease; Cytochrome P-450 CYP2C19; Female; Gene Frequency; Genotype; Graft Occlusion, Vascular; Heterozygote; Homozygote; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Prospective Studies; Stents; Ticlopidine | 2011 |
Gastrointestinal bleeding and outcomes after percutaneous coronary intervention for ST-segment elevation myocardial infarction.
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Female; Gastrointestinal Hemorrhage; Heparin; Hospital Mortality; Humans; Length of Stay; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Taiwan; Ticlopidine; Treatment Outcome | 2011 |
Simultaneous drug-eluting and bare-metal stent implantation: long-term clinical outcome and findings of clinically indicated coronary angiography.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Confidence Intervals; Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Multivariate Analysis; Paclitaxel; Platelet Aggregation Inhibitors; Prospective Studies; Statistics as Topic; Ticlopidine; Time Factors; Treatment Outcome | 2011 |
Proton pump inhibitor and clopidogrel interaction: have we forgotten aspirin?
Topics: Aspirin; Clopidogrel; Drug Interactions; Humans; Kinetics; Proton Pump Inhibitors; Ticlopidine | 2011 |
The unmet need of patients with atrial fibrillation: AVERROES and the novel oral anticoagulants.
Topics: Angiotensin II Type 1 Receptor Blockers; Anticoagulants; Aspirin; Atrial Fibrillation; Biphenyl Compounds; Clinical Trials, Phase III as Topic; Clopidogrel; Factor Xa Inhibitors; Fibrinolytic Agents; Humans; Intracranial Hemorrhages; Irbesartan; Platelet Aggregation Inhibitors; Pyrazoles; Pyridones; Stroke; Tetrazoles; Ticlopidine | 2011 |
[The CURRENT-OASIS 7 study].
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Confidence Intervals; Drug Administration Schedule; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Proportional Hazards Models; Randomized Controlled Trials as Topic; Salivary Ducts; Thrombosis; Ticlopidine | 2011 |
Randomized trial of aspirin and clopidogrel versus aspirin alone for the prevention of coronary artery bypass graft occlusion: the preoperative aspirin and postoperative antiplatelets in coronary artery bypass grafting surgery.
Topics: Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Drug Therapy, Combination; Graft Occlusion, Vascular; Humans; Myocardial Ischemia; Platelet Aggregation Inhibitors; Postoperative Care; Preoperative Care; Randomized Controlled Trials as Topic; Ticlopidine | 2011 |
Clopidogrel is not associated with major bleeding complications during peripheral arterial surgery.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Aspirin; Blood Transfusion; Chi-Square Distribution; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; New England; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Registries; Reoperation; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome; Vascular Surgical Procedures | 2011 |
Regarding "results of the randomized, placebo-controlled clopidogrel and acetylsalicylic acid in bypass surgery for peripheral arterial disease (CASPAR) trial".
Topics: Aspirin; Blood Vessel Prosthesis Implantation; Clopidogrel; Drug Therapy, Combination; Graft Occlusion, Vascular; Humans; Peripheral Arterial Disease; Placebo Effect; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine; Treatment Outcome; Veins | 2011 |
Feasibility and safety of 7-Fr radial approach for complex PCI.
Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Stenosis; Feasibility Studies; Female; Femoral Artery; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Radial Artery; Retrospective Studies; Ticlopidine; Ultrasonography, Interventional | 2011 |
High on treatment platelet reactivity and stent thrombosis.
Topics: Adult; Aged; Angioplasty; Aspirin; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine | 2011 |
The influencing factors for clopidogrel-mediated platelet inhibition are assay-dependent.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Austria; Biomarkers; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Drug Therapy, Combination; Female; Humans; Linear Models; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Receptors, Purinergic P2Y12; Reproducibility of Results; Risk Assessment; Risk Factors; Stents; Ticlopidine; Treatment Outcome | 2011 |
Results with Viabahn-assisted subintimal recanalization for TASC C and TASC D superficial femoral artery occlusive disease.
Topics: Aged; Aged, 80 and over; Amputation, Surgical; Ankle Brachial Index; Anticoagulants; Arterial Occlusive Diseases; Aspirin; Blood Vessel Prosthesis; Blood Vessel Prosthesis Implantation; Chi-Square Distribution; Clopidogrel; Endovascular Procedures; Female; Femoral Artery; Humans; Illinois; Male; Middle Aged; Platelet Aggregation Inhibitors; Prosthesis Design; Reoperation; Severity of Illness Index; Stents; Ticlopidine; Time Factors; Treatment Outcome; Ultrasonography, Doppler, Duplex; Vascular Patency; Warfarin | 2011 |
Recurrent ischemic stroke in a patient with ulcerative colitis and high levels of lipoprotein (a).
Topics: Anticholesteremic Agents; Anticoagulants; Aspirin; Atorvastatin; Blood Coagulation Tests; Carotid Stenosis; Clopidogrel; Colitis, Ulcerative; Female; Heparin, Low-Molecular-Weight; Heptanoic Acids; Humans; Lipoprotein(a); Magnetic Resonance Imaging; Middle Aged; Pyrroles; Risk Factors; Stroke; Thrombosis; Ticlopidine; Ultrasonography | 2011 |
Effects of platelet and inflammatory system activation on outcomes in diabetic patients with ST segment elevation myocardial infarction treated with primary percutaneous coronary intervention.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Restenosis; Diabetes Complications; Electrocardiography; Female; Humans; Inflammation; Male; Middle Aged; Myocardial Infarction; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2011 |
[Intracerebral hemorrhage in anticoagulated patients: what do we do afterwards?].
Topics: Aged; Anticoagulants; Aspirin; Cerebral Hemorrhage; Clopidogrel; Female; Follow-Up Studies; Humans; Intracranial Embolism; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Recurrence; Retrospective Studies; Risk; Risk Factors; Stroke; Ticlopidine; Vitamin K | 2012 |
Risk assessment of simple phacoemulsification in patients on combined anticoagulant and antiplatelet therapy.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Blood Loss, Surgical; Clopidogrel; Drug Therapy, Combination; Eye Hemorrhage; Female; Humans; Intraoperative Complications; Lens Implantation, Intraocular; Male; Middle Aged; Phacoemulsification; Platelet Aggregation Inhibitors; Postoperative Complications; Prospective Studies; Prothrombin Time; Risk Assessment; Thromboembolism; Ticlopidine; Warfarin | 2011 |
Comparison of drug-eluting versus bare metal stents in cardiac allograft vasculopathy.
Topics: Aspirin; Chi-Square Distribution; Clopidogrel; Coronary Angiography; Coronary Disease; Drug-Eluting Stents; Female; Heart Transplantation; Humans; Immunosuppressive Agents; Male; Metals; Middle Aged; Paclitaxel; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Sirolimus; Stents; Ticlopidine; Transplantation, Homologous; Treatment Outcome; Tubulin Modulators | 2011 |
Randomized controlled trial of dual antiplatelet therapy in patients undergoing surgery for critical limb ischemia.
Topics: Aspirin; Female; Humans; Ischemia; Leg; Male; Platelet Aggregation Inhibitors; Ticlopidine | 2014 |
The prevalence of co-administration of clopidogrel and proton pump inhibitors.
Topics: Aged, 80 and over; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Drug Utilization Review; Female; Gastrointestinal Hemorrhage; Humans; Male; New South Wales; Nursing Homes; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Risk Factors; Ticlopidine | 2011 |
Bleeding after percutaneous endoscopic gastrostomy is linked to serotonin reuptake inhibitors, not aspirin or clopidogrel.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Cohort Studies; Female; Gastrointestinal Hemorrhage; Gastroscopy; Gastrostomy; Humans; Male; Middle Aged; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Ticlopidine; Time Factors; Young Adult | 2011 |
Wireless pulmonary artery haemodynamic monitoring.
Topics: Anticoagulants; Aspirin; Clopidogrel; Electrodes, Implanted; Equipment Design; Female; Heart Failure; Hemodynamics; Humans; Male; Microchip Analytical Procedures; Monitoring, Physiologic; Pulmonary Artery; Pulmonary Wedge Pressure; Sensitivity and Specificity; Survival Analysis; Ticlopidine; Warfarin | 2011 |
A complex case of angulated and bifurcated lesion facilitated by excimer laser coronary angioplasty.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Stenosis; Humans; Lasers, Excimer; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine | 2011 |
Detection of clopidogrel hyporesponsiveness using a point-of-care assay and the impact of additional cilostazol administration after coronary stent implantation in diabetic patients.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Chi-Square Distribution; Cilostazol; Clopidogrel; Coronary Disease; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Humans; Logistic Models; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Predictive Value of Tests; Purinergic P2Y Receptor Antagonists; Registries; Republic of Korea; Risk Assessment; Risk Factors; Stents; Tetrazoles; Ticlopidine; Treatment Outcome | 2011 |
Effect of upstream clopidogrel treatment in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Female; Graft Occlusion, Vascular; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Propensity Score; Shock, Cardiogenic; Stents; Ticlopidine; Treatment Outcome | 2011 |
Late bare-metal stent thrombosis in a patient with Crohn's disease.
Topics: Adult; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Crohn Disease; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine | 2011 |
Reduced antiplatelet therapy after drug-eluting stenting: multicenter Janus Flex carbostent implantation with short dual antiplatelet treatment for 2 or 6 months-MATRIX study.
Topics: Aged; Aspirin; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hospitals, High-Volume; Humans; Italy; Kaplan-Meier Estimate; Logistic Models; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proportional Hazards Models; Prospective Studies; Prosthesis Design; Registries; Risk Assessment; Risk Factors; Tacrolimus; Ticlopidine; Time Factors; Treatment Outcome | 2012 |
Have medical therapy and stenting been fairly compared? A repercussion upon termination of recruitment in the SAMMPRIS trial.
Topics: Angioplasty; Aspirin; Carotid Stenosis; Clinical Trials as Topic; Clopidogrel; Humans; National Institute of Neurological Disorders and Stroke (U.S.); Platelet Aggregation Inhibitors; Stents; Stroke; Ticlopidine; United States | 2011 |
Atorvastatin and clopidogrel interfere with photosensitization in vitro.
Topics: Animals; Anticholesteremic Agents; Aspirin; Atorvastatin; Cathepsin B; Cell Line; Clopidogrel; Heptanoic Acids; Humans; Light; Macrophages; Mice; Neoplasms; Photochemotherapy; Photosensitizing Agents; Polyethylene Glycols; Polylysine; Porphyrins; Pyrroles; Ticlopidine | 2011 |
Relation of body mass index to on-treatment (clopidogrel + aspirin) platelet reactivity.
Topics: Adenosine Diphosphate; Aspirin; Body Mass Index; Cell Adhesion Molecules; Clopidogrel; Coronary Disease; Female; Humans; Logistic Models; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Platelet Aggregation; Platelet Function Tests; Risk Factors; Statistics, Nonparametric; Ticlopidine | 2011 |
Dose-related effect of statins in venous thrombosis risk reduction.
Topics: Aged; Aspirin; Atherosclerosis; Cerebral Infarction; Clopidogrel; Cohort Studies; Cross-Sectional Studies; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Proportional Hazards Models; Pulmonary Embolism; Retrospective Studies; Risk Reduction Behavior; Ticlopidine; Venous Thromboembolism | 2011 |
Impact of adjunctive cilostazol therapy versus high maintenance dose of clopidogrel in suboptimal responders with diabetes mellitus.
Topics: Aspirin; Blood Coagulation; Blood Platelets; Cilostazol; Clopidogrel; Diabetes Mellitus, Type 2; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Randomized Controlled Trials as Topic; Receptors, Purinergic P2Y12; Tetrazoles; Thrombosis; Ticlopidine | 2012 |
Safety of dental extractions during uninterrupted single or dual antiplatelet treatment.
Topics: Aged; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Greece; Hemostatics; Humans; Incidence; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Retrospective Studies; Ticlopidine; Time Factors; Tooth Extraction | 2011 |
Non-cardiac surgery in patients with coronary stents: the RECO study.
Topics: Administration, Oral; Aged; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Cerebrovascular Disorders; Chi-Square Distribution; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Female; France; Humans; Logistic Models; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Prospective Studies; Risk Assessment; Risk Factors; Stents; Surgical Procedures, Operative; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2011 |
Influence of low-dose aspirin (81 mg) on the incidence of definite stent thrombosis in patients receiving bare-metal and drug-eluting stents.
Topics: Aspirin; Clopidogrel; Coronary Restenosis; Coronary Thrombosis; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Immunosuppressive Agents; Incidence; Male; Middle Aged; Paclitaxel; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Assessment; Sirolimus; Statistics as Topic; Ticlopidine | 2011 |
Involvement of circulating platelets on the hyperalgesic response evoked by carrageenan and Bothrops jararaca snake venom.
Topics: Animals; Aspirin; Blood Platelets; Bothrops; Busulfan; Carrageenan; Clopidogrel; Crotalid Venoms; Cyclooxygenase 1; Hyperalgesia; Male; Rats; Rats, Wistar; Thrombocytopenia; Ticlopidine | 2011 |
Early aggressive medical management for patients with symptomatic intracranial stenosis.
Topics: Aged; Antihypertensive Agents; Aspirin; Biomarkers; Blood Pressure; Body Mass Index; Cerebral Angiography; Chi-Square Distribution; Clopidogrel; Combined Modality Therapy; Constriction, Pathologic; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracranial Arteriosclerosis; Lipoproteins, LDL; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Risk Reduction Behavior; Smoking Cessation; Ticlopidine; Time Factors; Tomography, X-Ray Computed; Treatment Outcome; Weight Loss | 2013 |
Reply to letter: "Randomized controlled trial of dual antiplatelet therapy in patients undergoing surgery for critical limb ischemia".
Topics: Aspirin; Female; Humans; Ischemia; Leg; Male; Platelet Aggregation Inhibitors; Ticlopidine | 2014 |
Dual oral antiplatelet therapy and unplanned surgery: possible role for intravenous platelet glycoprotein receptor inhibitors.
Topics: Administration, Oral; Aged; Angioplasty, Balloon, Coronary; Aspirin; Biliary Tract Surgical Procedures; Cardiovascular Diseases; Cholangitis; Choledocholithiasis; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Humans; Infusions, Intravenous; Male; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine; Tirofiban; Treatment Outcome; Tyrosine | 2011 |
Aspirin plus clopidogrel versus aspirin alone after coronary artery bypass grafting.
Topics: Aspirin; Cerebrovascular Circulation; Clopidogrel; Coronary Artery Bypass; Coronary Vessels; Drug Therapy, Combination; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Thrombosis; Ticlopidine | 2011 |
Differential effect of clopidogrel and aspirin on the release of BDNF from platelets.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Brain-Derived Neurotrophic Factor; Clopidogrel; Gene Expression Regulation; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors; Transforming Growth Factor beta1 | 2011 |
Malaysia-ACute CORonary syndromes Descriptive study (ACCORD): evaluation of compliance with existing guidelines in patients with acute coronary syndrome.
Topics: Acute Coronary Syndrome; Adult; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Guideline Adherence; Humans; Malaysia; Male; Medication Adherence; Middle Aged; Platelet Aggregation Inhibitors; Practice Patterns, Physicians'; Prospective Studies; Risk Factors; Ticlopidine | 2011 |
Patent foramen ovale may be causal for the first stroke but unrelated to subsequent ischemic events.
Topics: Adult; Aged; Aspirin; Brain Ischemia; Clopidogrel; Female; Follow-Up Studies; Foramen Ovale, Patent; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Recurrence; Stroke; Ticlopidine; Treatment Outcome | 2011 |
Clinical and prognostic implications of the initial response to aspirin in patients with acute coronary syndrome.
Topics: Acute Coronary Syndrome; Administration, Oral; Aspirin; Clopidogrel; Electrocardiography; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine; Time Factors; Treatment Outcome | 2011 |
Antiplatelet therapy in percutaneous coronary intervention: is variability of response clinically relevant?
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Combined Modality Therapy; Coronary Thrombosis; Drug Therapy, Combination; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2011 |
Relationship between cardiovascular outcomes and proton pump inhibitor use in patients receiving dual antiplatelet therapy after acute coronary syndrome.
Topics: Acute Coronary Syndrome; Aged; Aryl Hydrocarbon Hydroxylases; Aspirin; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Cytochrome P-450 CYP2C19; Databases, Factual; Drug Interactions; Esomeprazole; Female; Herb-Drug Interactions; Hospitalization; Humans; Male; Middle Aged; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Recurrence; Retrospective Studies; Ticlopidine; Treatment Outcome | 2011 |
Letter by Gasparovic et al regarding article, "Aspirin plus clopidogrel versus aspirin alone after coronary artery bypass grafting: the clopidogrel after surgery for coronary artery disease (CASCADE) trial".
Topics: Aspirin; Clopidogrel; Combined Modality Therapy; Coronary Artery Bypass; Coronary Artery Disease; Drug Resistance; Follow-Up Studies; Graft Occlusion, Vascular; Hemorheology; Humans; Hyperplasia; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Saphenous Vein; Ticlopidine; Tunica Intima | 2011 |
Letter by Bisdas et al regarding article, "Aspirin plus clopidogrel versus aspirin alone after coronary artery bypass grafting: the clopidogrel after surgery for coronary artery disease (CASCADE) trial".
Topics: Aspirin; Biotransformation; Clopidogrel; Combined Modality Therapy; Coronary Artery Bypass; Coronary Artery Disease; Cytochrome P-450 Enzyme System; Drug Interactions; Drug Resistance; Follow-Up Studies; Graft Occlusion, Vascular; Humans; Hyperplasia; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Saphenous Vein; Ticlopidine; Tunica Intima | 2011 |
Emergency surgery following trancutaneous aortic valve insertion.
Topics: Aged, 80 and over; Aortic Valve; Aspirin; Blood Loss, Surgical; Clopidogrel; Emergency Medical Services; Femoral Neck Fractures; Heart Valve Prosthesis Implantation; Humans; Male; Platelet Aggregation Inhibitors; Postoperative Complications; Ticlopidine | 2011 |
Acetylsalicylic acid, but not clopidogrel, inhibits therapeutically induced cerebral arteriogenesis in the hypoperfused rat brain.
Topics: Animals; Aspirin; Brain Ischemia; Cell Line; Cerebral Angiography; Cerebrovascular Circulation; Chemotaxis, Leukocyte; Clopidogrel; Disease Models, Animal; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Male; Monocytes; Neovascularization, Physiologic; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Ticlopidine; Vasodilation | 2012 |
Anticoagulation and clinically significant postoperative vitreous hemorrhage in diabetic vitrectomy.
Topics: Anticoagulants; Aspirin; Clopidogrel; Diabetic Retinopathy; Female; Humans; Incidence; Intraoperative Complications; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Retrospective Studies; Risk Factors; Ticlopidine; Treatment Outcome; Visual Acuity; Vitrectomy; Vitreous Hemorrhage; Warfarin | 2011 |
Atrial fibrillation treatment update.
Topics: Aspirin; Atrial Fibrillation; Clopidogrel; Heart Rate; Humans; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Thromboembolism; Ticlopidine | 2011 |
Determination of cut-off levels for on-clopidogrel platelet aggregation based on functional CYP2C19 gene variants in patients undergoing elective percutaneous coronary intervention.
Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Genotype; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine; Treatment Outcome | 2011 |
Time dependence of clopidogrel loading effect: platelet activation versus platelet aggregation.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Annexin A5; Aspirin; Baltimore; Clopidogrel; Collagen; Coronary Artery Disease; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Stents; Ticlopidine; Time Factors; Treatment Outcome | 2012 |
Comparison of venous and arterial blood sampling for the assessment of platelet aggregation with whole blood impedance aggregometry.
Topics: Adenosine Diphosphate; Arachidonic Acid; Area Under Curve; Arteries; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Electric Impedance; Female; Humans; Male; Phlebotomy; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Research Design; Specimen Handling; Ticlopidine; Veins | 2011 |
Comparison of platelet reactivity and clopidogrel response in patients ≤ 75 Years Versus > 75 years undergoing percutaneous coronary intervention for non-ST-segment elevation acute coronary syndrome.
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Age Factors; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Resistance; Follow-Up Studies; Hemorrhage; Humans; Middle Aged; Myocardial Ischemia; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Recurrence; Stents; Ticlopidine | 2011 |
Safety of ultrasound-guided fine needle aspiration biopsy of neck lesions in patients taking antithrombotic/anticoagulant medications.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Biopsy, Fine-Needle; Chi-Square Distribution; Clopidogrel; Female; Head and Neck Neoplasms; Hematoma; Hemorrhage; Heparin; Humans; Male; Middle Aged; Retrospective Studies; Ticlopidine; Ultrasonography, Interventional; Warfarin | 2011 |
[Platelet aggregation upon acetylsalicylic acid and clopidogrel treatment and glycoprotein IIb/IIIa content in patients with acute coronary syndrome].
Topics: Acute Coronary Syndrome; Aspirin; Blood Platelets; Clopidogrel; Drug Administration Schedule; Drug Dosage Calculations; Electrocardiography; Female; Humans; Male; Nephelometry and Turbidimetry; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine; Time Factors | 2011 |
Comparison of characteristics, management practices, and outcomes of patients between the global registry and the gulf registry of acute coronary events.
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Aged; Angiotensin Receptor Antagonists; Aspirin; Cardiac Catheterization; Clopidogrel; Diabetes Mellitus; Female; Fibrinolytic Agents; Heart Failure; Hemorrhage; Hospitalization; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Male; Mechanical Thrombolysis; Middle Aged; Middle East; Myocardial Revascularization; Platelet Aggregation Inhibitors; Registries; Sex Distribution; Shock, Cardiogenic; Smoking; Stroke; Ticlopidine | 2011 |
Impact of dyspnea on medical utilization and affiliated costs in patients with acute coronary syndrome.
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Costs and Cost Analysis; Diagnostic Techniques and Procedures; Drug Therapy, Combination; Dyspnea; Emergency Service, Hospital; Female; Humans; Insurance Claim Review; Male; Middle Aged; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Ticlopidine | 2011 |
Three-year clinical outcome with the Endeavor™ zotarolimus-eluting stent in primary percutaneous coronary intervention for ST elevation myocardial infarction: the Endeavor™ primary PCI study (E-PPCI).
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Confidence Intervals; Drug-Eluting Stents; Female; Heparin; Humans; Immunosuppressive Agents; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Prospective Studies; Sirolimus; Ticlopidine; Time Factors; Treatment Outcome; United Kingdom | 2011 |
Optical coherence tomography findings during "evolving" stent thrombosis.
Topics: Abciximab; Antibodies, Monoclonal; Anticoagulants; Aspirin; Cardiopulmonary Resuscitation; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Coronary Vessels; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Stents; Ticlopidine; Tomography, Optical Coherence; Ultrasonography, Interventional | 2011 |
Desperate times, desperate measures: rotablating dissections in acute myocardial infarction.
Topics: Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Aortic Dissection; Aspirin; Atherectomy, Coronary; Clopidogrel; Female; Heparin; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine | 2011 |
Normal chest radiograph and ground glass opacities on a thoracic computed tomographic scan in a patient with diffuse alveolar haemorrhage due to dual antiplatelet therapy prescribed after patent foramen ovale percutaneous device closure.
Topics: Adult; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Foramen Ovale, Patent; Hemoptysis; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Pulmonary Alveoli; Septal Occluder Device; Ticlopidine; Tomography, X-Ray Computed | 2011 |
Ticagrelor (Brilinta)--better than clopidogrel (Plavix)?
Topics: Adenosine; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Approval; Drug Interactions; Drug Therapy, Combination; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Randomized Controlled Trials as Topic; Thiophenes; Ticagrelor; Ticlopidine; United States | 2011 |
Prolonged use of aspirin alters human and rat intestinal cells and thereby limits the absorption of clopidogrel.
Topics: Animals; Aspirin; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Cell Survival; Clopidogrel; Drug Administration Schedule; Drug Interactions; Humans; Intestinal Absorption; Intestinal Mucosa; Male; Rats; Rats, Sprague-Dawley; Ticlopidine | 2011 |
Antithrombotic therapy use at discharge and 1 year in patients with atrial fibrillation and acute stroke: results from the AVAIL Registry.
Topics: Aged; Aged, 80 and over; Aspirin; Atrial Fibrillation; Clopidogrel; Drug Therapy, Combination; Female; Fibrinolytic Agents; Follow-Up Studies; Humans; Male; Middle Aged; Registries; Risk Factors; Stroke; Ticlopidine; Warfarin | 2011 |
Aspirin, clopidogrel, and warfarin use and outcomes in a cohort of 580 patients discharged after hospitalization for decompensated heart failure.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Aspirin; Chi-Square Distribution; Chronic Disease; Clopidogrel; Drug Interactions; Drug Utilization; Female; Health Care Surveys; Heart Failure; Humans; Male; Middle Aged; Patient Discharge; Patient Readmission; Platelet Aggregation Inhibitors; Practice Patterns, Physicians'; Proportional Hazards Models; Prospective Studies; Risk Factors; Stroke Volume; Ticlopidine; Time Factors; Turkey; Ventricular Function, Left; Warfarin | 2012 |
One-year outcomes with angiographic follow-up of paclitaxel-eluting balloon for the treatment of in-stent restenosis: insights from Spanish multicenter registry.
Topics: Angioplasty, Balloon; Anticoagulants; Antineoplastic Agents, Phytogenic; Aspirin; Clopidogrel; Confidence Intervals; Coronary Angiography; Coronary Restenosis; Drug-Eluting Stents; Female; Heparin; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Paclitaxel; Prospective Studies; Registries; Spain; Ticlopidine; Time Factors; Treatment Outcome | 2011 |
[Antiplatelet agents increase hemorrhagic risk in patients undergoing a cardiac pacemaker or ICD implantation].
Topics: Adult; Aged; Aged, 80 and over; Algorithms; Aspirin; Clopidogrel; Defibrillators, Implantable; Drug Therapy, Combination; France; Humans; Incidence; Length of Stay; Middle Aged; Multivariate Analysis; Pacemaker, Artificial; Platelet Aggregation Inhibitors; Postoperative Care; Postoperative Hemorrhage; Retrospective Studies; Risk Assessment; Risk Factors; Ticlopidine | 2011 |
Residual platelet reactivity after aspirin and clopidogrel treatment predicts 2-year major cardiovascular events in patients undergoing percutaneous coronary intervention.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Incidence; Male; Middle Aged; Myocardial Infarction; Platelet Activation; Platelet Aggregation Inhibitors; Preoperative Care; Prognosis; Retrospective Studies; Stroke; Survival Rate; Taiwan; Ticlopidine; Time Factors | 2011 |
Clopidogrel vs. aspirin treatment on admission improves 5-year survival after a first-ever acute ischemic stroke. data from the Athens Stroke Outcome Project.
Topics: Aged; Aspirin; Clopidogrel; Female; Greece; Humans; Male; Middle Aged; Multivariate Analysis; Patient Admission; Retrospective Studies; Ticlopidine | 2011 |
Intravascular ultrasound and angiographic demonstration of left main stem thrombus-high-risk presentation in a young adult with anabolic steroid abuse.
Topics: Abciximab; Anabolic Agents; Antibodies, Monoclonal; Aspirin; Clopidogrel; Coronary Angiography; Coronary Thrombosis; Humans; Immunoglobulin Fab Fragments; Male; Platelet Aggregation Inhibitors; Substance-Related Disorders; Ticlopidine; Ultrasonography, Interventional; Young Adult | 2010 |
High residual platelet reactivity after clopidogrel loading and long-term cardiovascular events among patients with acute coronary syndromes undergoing PCI.
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Aged; Angioplasty; Aspirin; Clopidogrel; Death; Female; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Revascularization; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Prognosis; Prospective Studies; Risk; Stents; Stroke; Thrombosis; Ticlopidine | 2011 |
Aborted myocardial infarction in a patient with rapid progression of Wellens syndrome.
Topics: Aspirin; Clopidogrel; Coronary Stenosis; Early Diagnosis; Electrocardiography; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Syndrome; Ticlopidine | 2012 |
Risk of bleeding associated with combined use of selective serotonin reuptake inhibitors and antiplatelet therapy following acute myocardial infarction.
Topics: Adrenal Cortex Hormones; Age Factors; Aged; Anemia; Angioplasty; Anticoagulants; Antihypertensive Agents; Aspirin; Canada; Citalopram; Clopidogrel; Cohort Studies; Drug Therapy, Combination; Female; Fluoxetine; Fluvoxamine; Heart Failure; Hemorrhage; Humans; Hypoglycemic Agents; Male; Middle Aged; Myocardial Infarction; Neoplasms; Paroxetine; Peptic Ulcer; Platelet Aggregation Inhibitors; Renal Insufficiency; Retrospective Studies; Risk; Risk Factors; Secondary Prevention; Selective Serotonin Reuptake Inhibitors; Sertraline; Sex Factors; Ticlopidine | 2011 |
Effects of P2Y(1) receptor antagonism on the reactivity of platelets from patients with stable coronary artery disease using aspirin and clopidogrel.
Topics: Adenosine Diphosphate; Aged; Aspirin; Blood Platelets; Clopidogrel; Collagen; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y1; Receptors, Thrombin; Thrombosis; Ticlopidine | 2012 |
A case of acute stent thrombosis during treatment with the thrombopoietin receptor agonist peptide--romiplostim.
Topics: Acute Disease; Aspirin; Chest Pain; Clopidogrel; Eptifibatide; Female; Humans; Middle Aged; Peptides; Piperazines; Platelet Aggregation Inhibitors; Platelet Count; Prasugrel Hydrochloride; Purpura, Thrombocytopenic, Idiopathic; Receptors, Thrombopoietin; Risk Factors; Stents; Thiophenes; Thrombosis; Ticlopidine; Ultrasonography, Interventional | 2012 |
Thrombus formation on a left atrial appendage closure device.
Topics: Aged; Anticoagulants; Aspirin; Atrial Appendage; Atrial Fibrillation; Clopidogrel; Equipment Design; Heart Diseases; Heparin; Humans; Male; Postoperative Complications; Septal Occluder Device; Thrombophilia; Thrombosis; Ticlopidine; Ultrasonography | 2011 |
Correlation between point-of-care platelet function testing and bleeding after coronary artery surgery.
Topics: Aged; Aspirin; Blood Transfusion; Clopidogrel; Coronary Artery Bypass; Coronary Vessels; Female; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Postoperative Care; Postoperative Hemorrhage; Ticlopidine | 2012 |
[Diagnostic laparoscopy under dual antiplatelet therapy with clopidogrel and aspirin].
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Diagnosis, Differential; Drug Substitution; Drug Therapy, Combination; Drug-Eluting Stents; Eptifibatide; Female; Humans; Laparoscopy; Multiple Myeloma; Peptides; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Risk Factors; Thrombosis; Ticlopidine | 2011 |
Treatment of a traumatic carotid-cavernous fistula by the sole use of a flow diverting stent.
Topics: Abducens Nerve Diseases; Accidents, Traffic; Angiography, Digital Subtraction; Aspirin; Brain Injuries; Carotid Artery, Internal; Carotid-Cavernous Sinus Fistula; Cerebral Angiography; Clopidogrel; Craniocerebral Trauma; Exophthalmos; Female; Humans; Ophthalmic Artery; Orbit; Paralysis; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Tomography, X-Ray Computed; Young Adult | 2012 |
Stent assisted coiling of the ruptured wide necked intracranial aneurysm.
Topics: Adult; Aneurysm, Ruptured; Aspirin; Clopidogrel; Cohort Studies; Embolization, Therapeutic; Female; Follow-Up Studies; Humans; Intracranial Aneurysm; Male; Middle Aged; Prospective Studies; Radiography; Retrospective Studies; Stents; Ticlopidine | 2012 |
Body weight: a risk factor for subtherapeutic antithrombotic therapy in neurovascular stenting.
Topics: Aspirin; Body Mass Index; Body Weight; Carotid Stenosis; Cerebrovascular Disorders; Clopidogrel; Female; Fibrinolytic Agents; Humans; Intracranial Aneurysm; Male; Middle Aged; Retrospective Studies; Risk Factors; Stents; Thrombolytic Therapy; Ticlopidine; Treatment Failure | 2011 |
Impact of preinjury warfarin and antiplatelet agents on outcomes of trauma patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Child; Child, Preschool; Clopidogrel; Cohort Studies; Female; Humans; Infant; Intracranial Hemorrhages; Length of Stay; Male; Middle Aged; Multivariate Analysis; New York; Platelet Aggregation Inhibitors; Registries; Retrospective Studies; Risk Factors; Ticlopidine; Trauma Centers; Warfarin; Wounds and Injuries; Young Adult | 2011 |
Platelet response to standard aspirin and clopidogrel treatment correlates with long-term outcome in patients with acute ST-elevation myocardial infarction.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Clopidogrel; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation; Ticlopidine; Time Factors; Treatment Outcome | 2011 |
Interaction analysis between genetic polymorphisms and pharmacodynamic effect in patients treated with adjunctive cilostazol to dual antiplatelet therapy: results of the ACCEL-TRIPLE (Accelerated Platelet Inhibition by Triple Antiplatelet Therapy Accordin
Topics: Aged; Aryl Hydrocarbon Hydroxylases; Aspirin; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cilostazol; Clopidogrel; Cohort Studies; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Regression Analysis; Tetrazoles; Ticlopidine | 2012 |
Carbon monoxide-releasing molecule-2 enhances coagulation in rabbit plasma and decreases bleeding time in clopidogrel/aspirin-treated rabbits.
Topics: Administration, Oral; Animals; Aspirin; Bleeding Time; Blood Coagulation; Carbon Monoxide; Clopidogrel; Fibrinolytic Agents; Hemorrhage; Injections, Intravenous; Male; Organometallic Compounds; Plasma; Platelet Aggregation Inhibitors; Rabbits; Thrombelastography; Ticlopidine | 2011 |
Illustration of the impact of antiplatelet drugs on the genesis and management of chronic subdural hematoma.
Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Clopidogrel; Drug Therapy, Combination; Hematoma, Subdural, Acute; Hematoma, Subdural, Chronic; Humans; Male; Platelet Aggregation Inhibitors; Postoperative Complications; Remission Induction; Risk Factors; Ticlopidine; Withholding Treatment | 2012 |
Safety and efficacy of a pharmaco-invasive reperfusion strategy in rural ST-elevation myocardial infarction patients with expected delays due to long-distance transfers.
Topics: Adrenergic beta-Antagonists; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Emergency Treatment; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Reperfusion; Patient Transfer; Platelet Aggregation Inhibitors; Prospective Studies; Recurrence; Rural Health; Tenecteplase; Ticlopidine; Tissue Plasminogen Activator; Treatment Outcome | 2012 |
Selecting the optimal stroke prevention therapy in atrial fibrillation.
Topics: Aspirin; Atrial Fibrillation; Clopidogrel; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2011 |
Antiplatelet and anticoagulant therapy in patients with gastrointestinal bleeding: an 86-year-old woman with peptic ulcer disease.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Drug Interactions; Female; Gastrointestinal Hemorrhage; Humans; Peptic Ulcer; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine; Warfarin | 2011 |
Effect of CYP2C19*2 and *3 loss-of-function alleles on platelet reactivity and adverse clinical events in East Asian acute myocardial infarction survivors treated with clopidogrel and aspirin.
Topics: Aged; Alleles; Aryl Hydrocarbon Hydroxylases; Asia, Eastern; Asian People; Aspirin; Blood Platelets; Clopidogrel; Cytochrome P-450 CYP2C19; Female; Humans; Male; Middle Aged; Myocardial Infarction; Pharmacogenetics; Platelet Aggregation Inhibitors; Prognosis; Ticlopidine; Treatment Outcome | 2011 |
The HEART study: a real-world experience using the CID Chrono Carbostent in primary and rescue PCI.
Topics: Aged; Aspirin; Chi-Square Distribution; Chromium Alloys; Clopidogrel; Coated Materials, Biocompatible; Disease-Free Survival; Drug Therapy, Combination; Female; Hospital Mortality; Hospitals, High-Volume; Humans; Italy; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Odds Ratio; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proportional Hazards Models; Prosthesis Design; Recurrence; Registries; Risk Factors; Severity of Illness Index; Shock, Cardiogenic; Stents; Ticlopidine; Time Factors; Treatment Outcome | 2012 |
Perioperative management of patients receiving anticoagulant or antiplatelet therapy: a clinician-oriented and practical approach.
Topics: Anticoagulants; Aspirin; Blood Loss, Surgical; Clopidogrel; Evidence-Based Medicine; Humans; Perioperative Care; Platelet Aggregation Inhibitors; Risk Assessment; Surgical Procedures, Operative; Thromboembolism; Thrombolytic Therapy; Ticlopidine; Warfarin | 2011 |
Cost-effectiveness of prasugrel in a US managed care population.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Cost Control; Cost-Benefit Analysis; Drug Therapy, Combination; Female; Humans; Interviews as Topic; Male; Managed Care Programs; Middle Aged; Models, Economic; Outcome Assessment, Health Care; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Ticlopidine; United States | 2012 |
High platelet reactivity to multiple agonists during aspirin and clopidogrel treatment is indicative of a global hyperreactive platelet phenotype.
Topics: Aspirin; Atherosclerosis; Female; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine | 2012 |
Level of systolic blood pressure within the normal range and risk of recurrent stroke.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Benzimidazoles; Benzoates; Blood Pressure; Brain Ischemia; Clopidogrel; Diastole; Dipyridamole; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Recurrence; Reference Values; Risk; Stroke; Systole; Telmisartan; Ticlopidine; Vascular Diseases | 2011 |
Coronary artery stents and antiplatelet therapy in patients with cirrhosis.
Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Fatty Liver; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; Liver Transplantation; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Stents; Ticlopidine | 2012 |
Prognostic implications of early and long-term bleeding events in patients on one-year dual antiplatelet therapy following drug-eluting stent implantation.
Topics: Aged; Aspirin; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Humans; Incidence; Italy; Kaplan-Meier Estimate; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prevalence; Prosthesis Design; Registries; Risk Assessment; Risk Factors; Severity of Illness Index; Ticlopidine; Time Factors; Treatment Outcome | 2012 |
Medical management trumps stenting for intracranial arterial stenosis.
Topics: Angioplasty; Aspirin; Cerebral Arteries; Clopidogrel; Combined Modality Therapy; Constriction, Pathologic; Early Termination of Clinical Trials; Humans; Intracranial Arteriosclerosis; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Stents; Stroke; Ticlopidine | 2011 |
Post percutaneous coronary intervention antiplatelet therapy: current perceptions, prospects and perplexity.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Clopidogrel; Coronary Restenosis; Drug Resistance; Drug Therapy, Combination; Drug-Eluting Stents; Hemorrhage; Humans; Metals; Patient Selection; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Prosthesis Design; Risk Assessment; Risk Factors; Stents; Tetrazoles; Thiophenes; Thrombosis; Ticlopidine; Treatment Outcome | 2011 |
Clinical outcomes following coronary stenting in Japanese patients treated with and without proton pump inhibitor.
Topics: Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Asian People; Aspirin; Clopidogrel; Coronary Disease; Female; Follow-Up Studies; Heartburn; Hematemesis; Humans; Incidence; Japan; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Registries; Retrospective Studies; Stents; Stroke; Ticlopidine; Treatment Outcome | 2012 |
Anti-platelet therapy and managing ulcer risk.
Topics: Animals; Anti-Bacterial Agents; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Combined Modality Therapy; Cytochrome P-450 CYP2C19; Drug Interactions; Enzyme Inhibitors; Helicobacter Infections; Helicobacter pylori; Humans; Patient Selection; Peptic Ulcer; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Risk Assessment; Risk Factors; Ticlopidine | 2012 |
Managing antiplatelet therapy during ophthalmic procedures: communication is the key.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Cardiology; Clopidogrel; Humans; Interdisciplinary Communication; Ophthalmologic Surgical Procedures; Ophthalmology; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine | 2011 |
The relevance of P2Y(12)-receptor gene variation for the outcome of clopidogrel-treated patients undergoing elective coronary stent implantation: a clinical follow-up.
Topics: Adenosine Diphosphate; Aged; Aspirin; Clopidogrel; Female; Follow-Up Studies; Genetic Variation; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation; Polymorphism, Single Nucleotide; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Software; Stents; Ticlopidine | 2012 |
Dose-dependent effect of early antiplatelet therapy in acute ischaemic stroke.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Body Mass Index; Brain Ischemia; Clopidogrel; Dose-Response Relationship, Drug; Female; Humans; Ischemia; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Stroke; Ticlopidine | 2012 |
[Perioperative anti-platelet therapy management--protocol suggestion].
Topics: Aspirin; Blood Loss, Surgical; Clinical Protocols; Clopidogrel; Drug Therapy, Combination; Humans; Perioperative Care; Platelet Aggregation Inhibitors; Risk Factors; Thromboembolism; Ticlopidine | 2011 |
An unexpected evolution of symptomatic mild middle cerebral artery (MCA) stenosis: asymptomatic occlusion.
Topics: Adult; Aphasia; Aspirin; Clopidogrel; Female; Humans; Infarction, Middle Cerebral Artery; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Platelet Aggregation Inhibitors; Ticlopidine; Ultrasonography, Doppler, Transcranial | 2011 |
No one-size-fits-all: A tailored approach to antithrombotic therapy after stent implantation.
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Clopidogrel; Coronary Disease; Coronary Restenosis; Drug-Eluting Stents; Electrocardiography; Female; Humans; Male; Platelet Aggregation Inhibitors; Ticagrelor; Ticlopidine | 2012 |
Low mean corpuscular hemoglobin level is a predictor of discontinuation of antiplatelet therapy in patients with acute coronary syndrome.
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Thrombosis; Drug-Eluting Stents; Erythrocyte Indices; Female; Follow-Up Studies; Humans; Male; Middle Aged; Multivariate Analysis; Patient Compliance; Platelet Aggregation Inhibitors; Risk Factors; Stents; Ticlopidine | 2011 |
Editorial - do not throw the baby out with the bathwater….
Topics: Angioplasty; Aspirin; Carotid Stenosis; Clopidogrel; Humans; Multicenter Studies as Topic; National Institute of Neurological Disorders and Stroke (U.S.); Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stents; Stroke; Ticlopidine; United States | 2011 |
My patient just had a transient ischaemic attack. Can I predict his risk for stroke? Is stroke inevitable or preventable?
Topics: Aspirin; Clopidogrel; Evidence-Based Medicine; Humans; Ischemic Attack, Transient; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Secondary Prevention; Stroke; Ticlopidine; Time Factors; Treatment Outcome | 2011 |
Insufficient platelet inhibition is related to silent embolic cerebral infarctions after coronary angiography.
Topics: Aged; Aspirin; Atherosclerosis; Basilar Artery; Carotid Arteries; Cerebral Infarction; Clopidogrel; Coronary Angiography; Data Interpretation, Statistical; Diffusion Magnetic Resonance Imaging; Drug Resistance; Female; Hemoglobins; Humans; Intracranial Embolism; Leukocyte Count; Logistic Models; Magnetic Resonance Angiography; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Ticlopidine; Vertebral Artery | 2012 |
Clopidogrel responsiveness in stroke patients on a chronic aspirin regimen.
Topics: Aged; Aged, 80 and over; Aspirin; Brain Ischemia; Clopidogrel; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Equipment Design; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Point-of-Care Systems; Predictive Value of Tests; Reproducibility of Results; Stroke; Thrombelastography; Ticlopidine; Time Factors; Treatment Outcome | 2013 |
Gene therapy with iNOS enhances regional contractility and reduces delayed contrast enhancement in a model of postischemic congestive heart failure.
Topics: Animals; Anticoagulants; Aspirin; Clopidogrel; Contrast Media; Coronary Angiography; Coronary Stenosis; Disease Models, Animal; Drug Carriers; Female; Fibrosis; Gadolinium; Genes, Reporter; Genes, Synthetic; Genetic Therapy; Heart Failure; Liposomes; Magnetic Resonance Imaging; Male; Myocardial Contraction; Myocardial Ischemia; Nitric Oxide Synthase Type II; Random Allocation; Stents; Sus scrofa; Swine; Ticlopidine; Ventricular Dysfunction, Left | 2011 |
Cost-effectiveness of clopidogrel plus aspirin for stroke prevention in patients with atrial fibrillation in whom warfarin is unsuitable.
Topics: Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Clinical Trials as Topic; Clopidogrel; Cohort Studies; Computer Simulation; Cost-Benefit Analysis; Drug Therapy, Combination; Follow-Up Studies; Humans; Markov Chains; Medicare; Monte Carlo Method; Platelet Aggregation Inhibitors; Quality-Adjusted Life Years; Research Design; Risk Factors; Stroke; Survival Rate; Ticlopidine; Treatment Outcome; United States; Warfarin | 2012 |
Development and validation of a liquid chromatographic method for purity control of clopidogrel-acetylsalicylic acid in combined oral dosage forms.
Topics: Administration, Oral; Aspirin; Chromatography, Liquid; Chromatography, Reverse-Phase; Clopidogrel; Dosage Forms; Drug Combinations; Drug Contamination; Ticlopidine | 2012 |
Warfarin use in nursing home residents: results from the 2004 national nursing home survey.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Cross-Sectional Studies; Health Care Surveys; Humans; Middle Aged; Nursing Homes; Platelet Aggregation Inhibitors; Ticlopidine; United States; Warfarin | 2012 |
Beneficial impact of prolonged dual antiplatelet therapy after drug-eluting stent implantation.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Myocardial Revascularization; Off-Label Use; Platelet Aggregation Inhibitors; Registries; Retreatment; Retrospective Studies; Ticlopidine | 2012 |
Prior antiplatelet use and cardiovascular outcomes in patients presenting with acute coronary syndromes.
Topics: Acute Coronary Syndrome; Adult; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Follow-Up Studies; Hospital Mortality; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Registries; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome; Ventricular Dysfunction, Left | 2012 |
Persistence, adherence and outcomes with antiplatelet regimens following cerebral infarction in the Tayside Stroke Cohort.
Topics: Aged; Aspirin; Cerebral Infarction; Clopidogrel; Cohort Studies; Dipyridamole; Drug Prescriptions; Drug Therapy, Combination; Drug Utilization; Female; Humans; Male; Medical Record Linkage; Medical Records Systems, Computerized; Medication Adherence; Platelet Aggregation Inhibitors; Practice Patterns, Physicians'; Proportional Hazards Models; Radiography; Risk Assessment; Risk Factors; Scotland; Survival Analysis; Ticlopidine; Time Factors; Treatment Outcome | 2012 |
Occlusion of modified Blalock-Taussig shunt after clopidogrel cessation.
Topics: Anticoagulants; Aspirin; Blalock-Taussig Procedure; Clopidogrel; Fatal Outcome; Graft Occlusion, Vascular; Heart Arrest; Heart Septal Defects, Ventricular; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Male; Pulmonary Atresia; Reoperation; Status Epilepticus; Substance Withdrawal Syndrome; Ticlopidine; Tricuspid Atresia | 2012 |
Antiplatelet therapy for transient ischemic attack.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain Ischemia; Clopidogrel; Cognition Disorders; Diffusion Magnetic Resonance Imaging; Dipyridamole; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Primary Prevention; Prognosis; Secondary Prevention; Stroke; Ticlopidine | 2012 |
New look at antiplatelet agent-related peptic ulcer: an update of prevention and treatment.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Gastrointestinal Hemorrhage; Helicobacter Infections; Helicobacter pylori; Humans; Peptic Ulcer; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Proton Pump Inhibitors; Thiophenes; Ticlopidine | 2012 |
Successful use of glycoprotein IIb/IIIa inhibitor, heparin, and IABP during PCI in a post-neurosurgical patient with STEMI and cardiogenic shock due to very late bare-metal stent thrombosis.
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Heparin; Humans; Intra-Aortic Balloon Pumping; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Postoperative Complications; Shock, Cardiogenic; Spinal Fusion; Stents; Thrombosis; Ticlopidine | 2012 |
Anatomical and visual results of transconjunctival sutureless vitrectomy using subconjunctival anesthesia performed on select patients taking anticoagulant and antiplatelet agents.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Anticoagulants; Aspirin; Bupivacaine; Clopidogrel; Conjunctiva; Female; Humans; Intraoperative Complications; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Retrospective Studies; Suture Techniques; Ticlopidine; Treatment Outcome; Visual Acuity; Vitrectomy; Warfarin | 2012 |
Predictors and time trends in clopidogrel and proton pump inhibitor coprescription with low-dose acetylsalicylic acid.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cerebrovascular Disorders; Clopidogrel; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Practice Patterns, Physicians'; Primary Health Care; Proton Pump Inhibitors; Retrospective Studies; Risk Factors; Ticlopidine; Time Factors; United Kingdom | 2012 |
[Pharmacoeconomic analysis of dabigatran etexilate effectiveness in patients with nonvalvular atrial fibrillation].
Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Benzimidazoles; Blood Coagulation; Blood Coagulation Tests; Clopidogrel; Costs and Cost Analysis; Dabigatran; Humans; Insurance, Pharmaceutical Services; Models, Statistical; Outcome and Process Assessment, Health Care; Pyridines; Russia; Thromboembolism; Ticlopidine | 2012 |
Dual non-responsiveness to antiplatelet treatment is a stronger predictor of cardiac adverse events than isolated non-responsiveness to clopidogrel or aspirin.
Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Predictive Value of Tests; Prospective Studies; Ticlopidine; Treatment Outcome | 2013 |
Antithrombotic therapy for atrial fibrillation: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.
Topics: Administration, Oral; Anticoagulants; Aspirin; Atrial Fibrillation; Atrial Flutter; Benzimidazoles; beta-Alanine; Clopidogrel; Dabigatran; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electric Countershock; Evidence-Based Medicine; Fibrinolytic Agents; Hemorrhage; Humans; International Normalized Ratio; Risk Factors; Societies, Medical; Stroke; Ticlopidine; Vitamin K | 2012 |
[Aspirin response and related factors in aged patients].
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Arachidonic Acid; Aspirin; Coronary Artery Disease; Gastrointestinal Hemorrhage; Humans; Middle Aged; Myocardial Ischemia; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2011 |
Review of an article: Results of the randomized, placebo-controlled clopidogrel and acetylsalicylic acid in bypass surgery for peripheral arterial disease (CASPAR) trial. Jill J.F. Belch, MD, FRCP, John Dormandy, MD, FRCS, and the CASPAR Writing Committee
Topics: Aspirin; Blood Vessel Prosthesis Implantation; Female; Humans; Lower Extremity; Male; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Ticlopidine; Veins | 2012 |
[Perioperative management of antiplatelet therapy in thoracic surgery. A survey of German hospitals].
Topics: Arterial Occlusive Diseases; Aspirin; Attitude of Health Personnel; Brain Ischemia; Clopidogrel; Combined Modality Therapy; Data Collection; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Germany; Humans; Myocardial Infarction; Perioperative Care; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Stents; Surveys and Questionnaires; Thoracic Surgical Procedures; Ticlopidine | 2012 |
Combined antithrombotic treatment with aspirin and clopidogrel for patients with capsular warning syndrome: a case report.
Topics: Aged; Aspirin; Clopidogrel; Female; Humans; Internal Capsule; Intracranial Thrombosis; Ischemic Attack, Transient; Male; Middle Aged; Ticlopidine | 2012 |
Spontaneous remission after a year of romiplostim in an adult patient with refractory primary immune thrombocytopenia.
Topics: Antibodies, Monoclonal, Murine-Derived; Anticoagulants; Aspirin; Clopidogrel; Drug Resistance; Hemorrhage; Humans; Immunization, Passive; Male; Metabolic Syndrome; Middle Aged; Myocardial Infarction; Prednisone; Purpura, Thrombocytopenic, Idiopathic; Receptors, Fc; Recombinant Fusion Proteins; Remission, Spontaneous; Rituximab; Stents; Thrombopoiesis; Thrombopoietin; Ticlopidine | 2012 |
Serotonin antagonism improves platelet inhibition in clopidogrel low-responders after coronary stent placement: an in vitro pilot study.
Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Humans; In Vitro Techniques; Ketanserin; Light; Male; Middle Aged; Myocardial Infarction; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Serotonin; Serotonin Antagonists; Stents; Ticlopidine; Treatment Outcome | 2012 |
Inhibition of platelet aggregation by prostaglandin E1 (PGE1) in diabetic patients during therapy with clopidogrel and aspirin.
Topics: Adenosine Diphosphate; Aged; Alprostadil; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Cytochrome P-450 CYP2C19; Diabetes Mellitus; Female; Genotype; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Risk Factors; Ticlopidine | 2013 |
Time-dependent changes of myeloperoxidase in relation to in-hospital mortality in patients with the first anterior ST-segment elevation myocardial infarction treated by primary percutaneous coronary intervention.
Topics: Aged; Angioplasty; Angioplasty, Balloon, Coronary; Aspirin; Biomarkers; Blood Chemical Analysis; Clopidogrel; Coronary Angiography; Female; Heart Failure; Hospital Mortality; Humans; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Peroxidase; Predictive Value of Tests; Prospective Studies; ROC Curve; Ticlopidine; Time Factors; Troponin I | 2012 |
Do platelet function testing and genotyping improve outcome in patients treated with antithrombotic agents?: platelet function testing and genotyping improve outcome in patients treated with antithrombotic agents.
Topics: Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Fibrinolytic Agents; Genetic Testing; Genotype; Humans; Pharmacogenetics; Platelet Aggregation Inhibitors; Platelet Function Tests; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Risk Factors; Thrombosis; Ticlopidine | 2012 |
Do platelet function testing and genotyping improve outcome in patients treated with antithrombotic agents?: the role of platelet reactivity and genotype testing in the prevention of atherothrombotic cardiovascular events remains unproven.
Topics: Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Fibrinolytic Agents; Genetic Testing; Genotype; Humans; Pharmacogenetics; Platelet Aggregation Inhibitors; Platelet Function Tests; Prevalence; Prognosis; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Risk Factors; Thrombosis; Ticlopidine | 2012 |
Aneurysm formation after drug-eluting balloon treatment of drug-eluting in-stent restenosis: first case report.
Topics: Angina, Unstable; Angioplasty, Balloon, Coronary; Aspirin; Cardiac Catheters; Cardiovascular Agents; Clopidogrel; Coronary Aneurysm; Coronary Angiography; Coronary Restenosis; Drug Delivery Systems; Drug Therapy, Combination; Drug-Eluting Stents; Equipment Design; Humans; Male; Middle Aged; Paclitaxel; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors | 2012 |
Multicolor flow cytometry for evaluation of platelet surface antigens and activation markers.
Topics: Aspirin; Blood Platelets; Clopidogrel; Flow Cytometry; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombasthenia; Thrombocytopenia; Ticlopidine | 2012 |
Safety and efficacy of targeting platelet proteinase-activated receptors in combination with existing anti-platelet drugs as antithrombotics in mice.
Topics: Animals; Aspirin; Clopidogrel; Disease Models, Animal; Fibrinolytic Agents; Hemostasis; Mice; Mice, Knockout; Platelet Activation; Platelet Aggregation Inhibitors; Receptors, Proteinase-Activated; Thrombosis; Ticlopidine | 2012 |
Platelet transfusion for reversal of dual antiplatelet therapy in patients requiring urgent surgery: a pilot study.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Emergencies; Emergency Medical Services; Female; Germany; Humans; Male; Middle Aged; Pilot Projects; Platelet Aggregation Inhibitors; Platelet Transfusion; Postoperative Hemorrhage; Preoperative Care; Risk Assessment; Risk Factors; Ticlopidine; Treatment Outcome | 2012 |
Are the results of a regional ST-elevation myocardial infarction system reproducible?
Topics: Adrenergic beta-Antagonists; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clinical Protocols; Clopidogrel; Databases, Factual; Female; Fibrinolytic Agents; Heparin; Hospital Mortality; Humans; Iowa; Male; Middle Aged; Minnesota; Myocardial Infarction; Outcome and Process Assessment, Health Care; Platelet Aggregation Inhibitors; Prospective Studies; Regional Medical Programs; Tenecteplase; Ticlopidine; Time Factors; Tissue Plasminogen Activator; Transportation of Patients | 2012 |
Cigarette smoking is associated with a dose-response effect in clopidogrel-treated patients with diabetes mellitus and coronary artery disease: results of a pharmacodynamic study.
Topics: Aged; Aspirin; Biomarkers; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Disease; Cotinine; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Florida; Humans; Male; Microfilament Proteins; Middle Aged; Odds Ratio; Phosphoproteins; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Smoking; Ticlopidine; Time Factors; Treatment Outcome | 2012 |
The effects of clopidogrel (Plavix) and other oral anticoagulants on early hip fracture surgery.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Blood Loss, Surgical; Clopidogrel; Cohort Studies; Female; Hip Fractures; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Retrospective Studies; Risk Factors; Ticlopidine; Treatment Outcome; Warfarin | 2012 |
Usefulness of C-reactive protein as a marker of early post-infarct left ventricular systolic dysfunction.
Topics: Aged; Angioplasty, Balloon, Coronary; Anti-Arrhythmia Agents; Antihypertensive Agents; Aspirin; Biomarkers; C-Reactive Protein; Clopidogrel; Female; Heparin; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Perindopril; Platelet Aggregation Inhibitors; Prospective Studies; Risk Factors; Ticlopidine; Ventricular Dysfunction, Left | 2012 |
A case of acute coronary artery occlusion associated with very rapid onset heparin-induced thrombosis without thrombocytopenia.
Topics: Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagulants; Arginine; Aspirin; Autoantibodies; Cilostazol; Clopidogrel; Coronary Angiography; Coronary Occlusion; Drug Therapy, Combination; Female; Heart Failure; Heparin; Humans; Pipecolic Acids; Platelet Count; Platelet Factor 4; Stents; Sulfonamides; Tetrazoles; Thrombosis; Ticlopidine; Time Factors | 2012 |
A new model of gastric bleeding induced in rats by aspirin plus clopidogrel under stimulation of acid secretion. Prophylactic effects of antiulcer drugs.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Clopidogrel; Drug Interactions; Famotidine; Gastric Acid; Gastric Mucosa; Gastrointestinal Hemorrhage; Male; Omeprazole; Peroxidase; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Ticlopidine | 2012 |
Comparison of additional versus no additional heparin during therapeutic oral anticoagulation in patients undergoing percutaneous coronary intervention.
Topics: Administration, Oral; Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Fibrinolytic Agents; Follow-Up Studies; Heparin; Humans; Injections, Subcutaneous; Male; Platelet Aggregation Inhibitors; Postoperative Complications; Preoperative Care; Prospective Studies; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome; Warfarin | 2012 |
Computed tomography angiography evaluation of internal carotid artery free-floating thrombus--single-center diagnosis, false-positives, and follow-up.
Topics: Aged; Anticoagulants; Aspirin; Carotid Artery Diseases; Carotid Artery, Internal; Clopidogrel; Diagnosis, Differential; Female; Fibrinolytic Agents; Heparin; Humans; Male; Thrombosis; Ticlopidine; Tissue Plasminogen Activator; Tomography, X-Ray Computed | 2012 |
Gastrointestinal bleeding associated with antithrombotic therapy in the elderly in Japan.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Asian People; Aspirin; Chi-Square Distribution; Female; Fibrinolytic Agents; Gastrointestinal Hemorrhage; Hemostasis, Endoscopic; Hemostatic Techniques; Humans; Japan; Male; Middle Aged; Risk Assessment; Risk Factors; Ticlopidine; Treatment Outcome; Warfarin; Young Adult | 2012 |
Effects of PPIs and an H2 blocker on the antiplatelet function of clopidogrel in Japanese patients under dual antiplatelet therapy.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Asian People; Aspirin; Case-Control Studies; Clopidogrel; Coronary Artery Disease; Cross-Over Studies; Drug Therapy, Combination; Enzyme Inhibitors; Female; Histamine H2 Antagonists; Humans; Male; Omeprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Prognosis; Prospective Studies; Proton Pump Inhibitors; Rabeprazole; Ticlopidine | 2012 |
Individualised PPI prescription in patients on combination antiplatelet therapy and upper gastrointestinal events after percutaneous coronary intervention: a cohort study.
Topics: Acute Coronary Syndrome; Adrenal Cortex Hormones; Adverse Drug Reaction Reporting Systems; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Cohort Studies; Combined Modality Therapy; Coronary Angiography; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Peptic Ulcer; Platelet Aggregation Inhibitors; Precision Medicine; Proton Pump Inhibitors; Ticlopidine | 2012 |
Clinical and pathological improvement in stroke-prone spontaneous hypertensive rats related to the pleiotropic effect of cilostazol.
Topics: Animals; Aspirin; Biomarkers; Cerebral Infarction; Cilostazol; Clopidogrel; Hippocampus; Male; Nerve Tissue Proteins; Oxidative Stress; Platelet Aggregation Inhibitors; Rats; Rats, Inbred SHR; Receptor, IGF Type 1; Tetrazoles; Ticlopidine | 2012 |
Maintenance of anticoagulant and antiplatelet agents for patients undergoing peribulbar anesthesia and vitreoretinal surgery.
Topics: Acenocoumarol; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anticoagulants; Aspirin; Clopidogrel; Conscious Sedation; Electrocardiography; Eye Hemorrhage; Female; Humans; Male; Middle Aged; Orbit; Oximetry; Phenindione; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Retrospective Studies; Ticlopidine; Vitreoretinal Surgery; Warfarin; Young Adult | 2012 |
Impaired responsiveness to clopidogrel and aspirin in patients with recurrent stent thrombosis following percutaneous intervention for peripheral artery disease.
Topics: Aged; Angioplasty; Aspirin; Blood Platelets; Clopidogrel; Drug Resistance; Female; Humans; Male; Middle Aged; Peripheral Arterial Disease; Platelet Aggregation; Platelet Aggregation Inhibitors; Risk Factors; Stents; Thrombosis; Ticlopidine | 2013 |
Transient increase in pressure gradients after termination of dual antiplatelet therapy in a patient after transfemoral aortic valve implantation.
Topics: Aged; Aortic Valve Stenosis; Aspirin; Cardiac Catheterization; Clopidogrel; Dyspnea; Echocardiography, Doppler; Femoral Artery; Heart Valve Prosthesis Implantation; Hemodynamics; Humans; Male; Platelet Aggregation Inhibitors; Recovery of Function; Ticlopidine; Withholding Treatment | 2012 |
Age-related inducibility of carboxylesterases by the antiepileptic agent phenobarbital and implications in drug metabolism and lipid accumulation.
Topics: Age Factors; Animals; Animals, Newborn; Anticonvulsants; Aspirin; Carboxylic Ester Hydrolases; Clopidogrel; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Hydrolysis; Lipid Metabolism; Liver; Mice; Mice, Inbred C57BL; Naphthaleneacetic Acids; Phenobarbital; Ticlopidine | 2012 |
Triple antithrombotic therapy after coronary stenting in the elderly with atrial fibrillation: necessary or too hazardous?
Topics: Aspirin; Atrial Fibrillation; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Warfarin | 2012 |
Safety and effectiveness of antithrombotic strategies in older adult patients with atrial fibrillation and non-ST elevation myocardial infarction.
Topics: Aged; Aged, 80 and over; Aspirin; Atrial Fibrillation; Clopidogrel; Comorbidity; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fibrinolytic Agents; Hemorrhage; Humans; Male; Medicare; Myocardial Infarction; Patient Readmission; Proportional Hazards Models; Registries; Ticlopidine; Treatment Outcome; United States; Warfarin | 2012 |
Dual antiplatelet therapy after myocardial infarction and percutaneous coronary intervention: analysis of patient adherence using a French health insurance reimbursement database.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Cohort Studies; Databases, Factual; Drug Therapy, Combination; Female; France; Humans; Insurance, Health, Reimbursement; Male; Myocardial Infarction; Patient Compliance; Platelet Aggregation Inhibitors; Retrospective Studies; Ticlopidine | 2012 |
Personalised antiplatelet therapy in stent thrombosis: observations from the Clopidogrel Resistance in Stent Thrombosis (CREST) registry.
Topics: Aged; Aspirin; Clopidogrel; Coronary Thrombosis; Dose-Response Relationship, Drug; Drug Resistance; Electrocardiography; Female; Follow-Up Studies; Graft Occlusion, Vascular; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Prevalence; Prospective Studies; Registries; Thrombelastography; Ticlopidine; Treatment Outcome; United Kingdom | 2012 |
Interaction between ticlopidine or warfarin or cardioaspirin with a highly standardized deterpened Ginkgo biloba extract (VR456) in rat and human.
Topics: Animals; Aspirin; Blood Pressure; Drug Interactions; Ginkgo biloba; Ginkgolides; Heart Rate; Hemorrhage; International Normalized Ratio; Male; Partial Thromboplastin Time; Plant Extracts; Plant Leaves; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Ticlopidine; Warfarin | 2010 |
Clopidogrel response up to six months after acute myocardial infarction.
Topics: Aspirin; Clopidogrel; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine; Time Factors | 2012 |
[Resistance to antiplatelet agents assessed by a point-of-care platelet function test and thromboembolic adverse events in neurointervention].
Topics: Adult; Aged; Aspirin; Cilostazol; Clopidogrel; Drug Resistance; Female; Humans; Intracranial Aneurysm; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Tetrazoles; Thromboembolism; Ticlopidine | 2012 |
Effect of glycemic control on response to antiplatelet therapy in patients with diabetes mellitus and ST-segment elevation myocardial infarction.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Blood Glucose; Clopidogrel; Diabetic Cardiomyopathies; Electrocardiography; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine | 2012 |
Multiple gene polymorphisms predisposing to the prothrombotic state in an adolescent with acute myocardial infarction.
Topics: Adolescent; Anticoagulants; Aspirin; Cholesterol Ester Transfer Proteins; Clopidogrel; Coronary Angiography; Electrocardiography; Fibrinogen; Genetic Predisposition to Disease; Heparin; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Myocardial Infarction; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Thrombosis; Ticlopidine | 2012 |
Very late thrombosis of a paclitaxel-eluting stent after 72 months in a patient on dual anti-platelet therapy.
Topics: Aspirin; Clopidogrel; Coronary Thrombosis; Drug-Eluting Stents; Echocardiography; Electrocardiography; Humans; Male; Middle Aged; Myocardial Infarction; Paclitaxel; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors | 2012 |
Utility of VasoCT in the treatment of intracranial aneurysm with flow-diverter stents.
Topics: Adult; Aged; Angiography, Digital Subtraction; Angioplasty, Balloon; Aspirin; Catheterization; Cerebral Angiography; Cerebral Arteries; Clopidogrel; Female; Fluoroscopy; Follow-Up Studies; Graft Occlusion, Vascular; Humans; Intracranial Aneurysm; Male; Middle Aged; Neurosurgical Procedures; Platelet Aggregation Inhibitors; Postoperative Complications; Stents; Ticlopidine; Tomography, X-Ray Computed | 2012 |
Clopidogrel use before renal artery angioplasty with/without stent placement resulted in tertiary procedure risk reduction.
Topics: Aged; Angioplasty, Balloon; Aspirin; Clopidogrel; Comorbidity; Female; Humans; Life Tables; Male; Platelet Aggregation Inhibitors; Renal Artery Obstruction; Retreatment; Secondary Prevention; Stents; Ticlopidine | 2012 |
Do we have to stop anticoagulant and platelet-inhibitor treatments during proctological surgery?
Topics: Adult; Anticoagulants; Aspirin; Blood Transfusion; Chi-Square Distribution; Clopidogrel; Female; Hemorrhoids; Heparin; Humans; Male; Middle Aged; Multivariate Analysis; Patient Readmission; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Prospective Studies; Rectal Neoplasms; Ticlopidine | 2012 |
The effect of antiplatelet therapy in patients with inflammatory bowel disease.
Topics: Aspirin; Clopidogrel; Disease Progression; Female; Humans; Inflammatory Bowel Diseases; Male; Platelet Aggregation Inhibitors; Retrospective Studies; Ticlopidine | 2012 |
Comparison of bolus only with bolus plus infusion of bivalirudin in patients undergoing elective percutaneous coronary intervention: a retrospective observational study.
Topics: Aged; Alabama; Antithrombins; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Elective Surgical Procedures; Female; Hemorrhage; Hirudins; Humans; Incidence; Infusions, Intravenous; Injections, Intravenous; Ischemia; Male; Middle Aged; Peptide Fragments; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Recombinant Proteins; Retrospective Studies; Severity of Illness Index; Thrombosis; Ticlopidine | 2012 |
Dramatic effect of early clopidogrel administration in reducing mortality and MACE rates in ACS patients. Data from the Swiss registry AMIS-Plus.
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Aspirin; Cardiac Catheterization; Clopidogrel; Confidence Intervals; Drug Therapy, Combination; Electrocardiography; Female; Hospital Mortality; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Odds Ratio; Platelet Aggregation Inhibitors; Registries; Switzerland; Ticlopidine; Time Factors; Young Adult | 2012 |
Blood loss and complications following carotid endarterectomy in patients treated with clopidogrel.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Carotid Artery Diseases; Clopidogrel; Drug Therapy, Combination; Endarterectomy, Carotid; Female; Hematoma; Humans; Israel; Male; Middle Aged; Peripheral Nerve Injuries; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Retrospective Studies; Risk Assessment; Risk Factors; Stroke; Surgical Wound Infection; Ticlopidine; Time Factors; Treatment Outcome | 2012 |
Peripartum management of dual antiplatelet therapy and neuraxial labor analgesia after bare metal stent insertion for acute myocardial infarction.
Topics: Adult; Analgesia, Obstetrical; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Eptifibatide; Female; Humans; Metals; Myocardial Infarction; Nerve Block; Peptides; Peripartum Period; Platelet Aggregation Inhibitors; Pregnancy; Pregnancy Complications; Stents; Ticlopidine | 2012 |
[ST segment elevation-acute myocardial infarction management at the office: clopidogrel or aspirin?].
Topics: Aged; Anterior Wall Myocardial Infarction; Aspirin; Choice Behavior; Clopidogrel; Electrocardiography; Female; Humans; Physicians' Offices; Platelet Aggregation Inhibitors; Referral and Consultation; Ticlopidine | 2012 |
Pharmacodynamic effect of clopidogrel therapy and switching to cilostazol in patients with the CYP2C19 loss-of-function allele (ACCEL-SWITCH) study.
Topics: Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Asian People; Aspirin; Cilostazol; Clopidogrel; Coronary Restenosis; Coronary Thrombosis; Cytochrome P-450 CYP2C19; Drug Administration Schedule; Drug Substitution; Drug Therapy, Combination; Drug-Eluting Stents; Genotype; Heterozygote; Homozygote; Humans; Phenotype; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Republic of Korea; Tetrazoles; Ticlopidine; Time Factors; Treatment Outcome | 2012 |
Role of the laboratory in monitoring patients receiving dual antiplatelet therapy.
Topics: Adult; Aged; Aged, 80 and over; Angioplasty; Aspirin; Clinical Laboratory Techniques; Clopidogrel; Drug Resistance; Female; Humans; Logistic Models; Male; Middle Aged; Monitoring, Physiologic; Multivariate Analysis; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Reproducibility of Results; Sensitivity and Specificity; Stents; Thrombosis; Ticlopidine | 2012 |
Duration of dual antiplatelet therapy and long-term clinical outcome after coronary drug-eluting stent implantation: landmark analyses from the CREDO-Kyoto PCI/CABG Registry Cohort-2.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Chi-Square Distribution; Clopidogrel; Cohort Studies; Coronary Artery Disease; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Humans; Japan; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Proportional Hazards Models; Prosthesis Design; Pyridines; Registries; Stroke; Ticlopidine; Time Factors; Treatment Outcome | 2012 |
The perioperative management of patients with coronary artery stents: surveying the clinical stakeholders and arriving at a consensus regarding optimal care.
Topics: Adult; Advisory Committees; Alabama; Anesthesiology; Aspirin; Blood Loss, Surgical; Cardiac Catheterization; Cardiology; Clopidogrel; Consensus; Coronary Vessels; Cross-Sectional Studies; Decision Making; Decision Support Techniques; Female; General Surgery; Health Care Surveys; Humans; Male; Middle Aged; Myocardial Ischemia; Perioperative Care; Perioperative Period; Physicians; Platelet Aggregation Inhibitors; Primary Health Care; Risk Factors; Sampling Studies; Stents; Surveys and Questionnaires; Thrombosis; Ticlopidine; Workforce | 2012 |
Simultaneous subacute thrombosis of bare metal coronary stents in two different arteries early after clopidogrel cessation.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Stenosis; Coronary Thrombosis; Drug Administration Schedule; Electrocardiography; Female; Humans; Medication Adherence; Metals; Middle Aged; Platelet Aggregation Inhibitors; Prosthesis Design; Stents; Ticlopidine; Time Factors; Treatment Outcome | 2012 |
Evaluation of the role of the new INNOVANCE PFA P2Y test cartridge in detection of clopidogrel resistance.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Blood Platelets; Case-Control Studies; Cell Adhesion Molecules; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Female; Humans; Longitudinal Studies; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Thrombosis; Ticlopidine | 2012 |
Economic evaluation of clopidogrel in acute coronary syndrome patients without ST-segment elevation in Greece: a cost-utility analysis.
Topics: Acute Coronary Syndrome; Aged; Angina, Unstable; Aspirin; Clopidogrel; Computer Simulation; Cost-Benefit Analysis; Drug Therapy, Combination; Female; Greece; Humans; Male; Markov Chains; Models, Economic; Platelet Aggregation Inhibitors; Quality-Adjusted Life Years; Secondary Prevention; Survival Analysis; Ticlopidine | 2012 |
Prolonged clopidogrel use after bare metal and drug-eluting stent placement: the Veterans Administration drug-eluting stent study.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Humans; Logistic Models; Male; Metals; Middle Aged; Multivariate Analysis; Myocardial Infarction; Platelet Aggregation Inhibitors; Propensity Score; Proportional Hazards Models; Prosthesis Design; Risk Assessment; Risk Factors; Stents; Ticlopidine; Time Factors; Treatment Outcome; United States; United States Department of Veterans Affairs | 2012 |
Risk of wound hematoma at carotid endarterectomy under dual antiplatelet therapy.
Topics: Aged; Aspirin; Blood Loss, Surgical; Clopidogrel; Drug Therapy, Combination; Endarterectomy, Carotid; Female; Hematoma; Humans; Male; Platelet Aggregation Inhibitors; Reoperation; Risk Factors; Ticlopidine | 2012 |
High post-clopidogrel platelet reactivity assessed by a point-of-care assay predicts long-term clinical outcomes in patients with ST-segment elevation myocardial infarction who underwent primary coronary stenting.
Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Cohort Studies; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Point-of-Care Systems; Predictive Value of Tests; Prospective Studies; Stents; Ticlopidine; Treatment Outcome | 2013 |
Adherence to guidelines for the prescribing of double and triple combinations of antithrombotic agents.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Attitude of Health Personnel; Clopidogrel; Community Pharmacy Services; Comorbidity; Drug Interactions; Drug Prescriptions; Drug Therapy, Combination; Drug Utilization Review; Female; Fibrinolytic Agents; Guideline Adherence; Health Care Surveys; Health Knowledge, Attitudes, Practice; Hemorrhage; Humans; Male; Middle Aged; Netherlands; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Practice Patterns, Physicians'; Retrospective Studies; Risk Assessment; Risk Factors; Surveys and Questionnaires; Ticlopidine; Vitamin K | 2014 |
Long-term successful percutaneous coronary intervention in factor VII deficiency.
Topics: Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Stenosis; Diabetes Mellitus, Type 2; Factor VII Deficiency; Follow-Up Studies; Humans; Male; Middle Aged; Obesity, Morbid; Platelet Aggregation Inhibitors; Radiography; Risk Assessment; Stents; Thromboembolism; Ticlopidine; Time Factors; Treatment Outcome | 2012 |
CYP2C19 genotype-guided antiplatelet therapy in a patient with clopidogrel resistance.
Topics: Aged; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug Resistance; Genotype; Humans; Male; Piperazines; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Stents; Thiophenes; Ticlopidine; Treatment Outcome | 2012 |
Massive epistaxis in a patient with Eisenmenger syndrome: illustrating the clot-versus-bleed conundrum.
Topics: Adult; Aspirin; Clopidogrel; Eisenmenger Complex; Epistaxis; Female; Humans; Platelet Aggregation Inhibitors; Thrombocytopenia; Thrombosis; Ticlopidine | 2011 |
Management of acute upper gastrointestinal bleeding: summary of NICE guidance.
Topics: Acute Disease; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Blood Component Transfusion; Clopidogrel; Contraindications; Endoscopy, Gastrointestinal; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Lypressin; Peptic Ulcer Hemorrhage; Proton Pump Inhibitors; Resuscitation; Risk Assessment; Secondary Prevention; Terlipressin; Ticlopidine; United Kingdom; Vasoconstrictor Agents; Warfarin | 2012 |
Clopidogrel in atrial fibrillation: is there any justification now in the era of new anticoagulants?
Topics: Aspirin; Atrial Fibrillation; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Stroke; Ticlopidine | 2012 |
Impact of age and anticoagulation: need for neurosurgical intervention in trauma patients with mild traumatic brain injury.
Topics: Age Factors; Aged; Anticoagulants; Aspirin; Brain Injuries; Clopidogrel; Craniotomy; Decompressive Craniectomy; Glasgow Coma Scale; Humans; Intracranial Hemorrhages; Middle Aged; Retrospective Studies; Ticlopidine; Time Factors; Tomography, X-Ray Computed; Warfarin | 2012 |
Safety of temporary and permanent suspension of antiplatelet therapy after drug eluting stent implantation in contemporary "real-world" practice.
Topics: Aged; Analysis of Variance; Aspirin; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Female; Health Status Indicators; Humans; Male; Platelet Aggregation Inhibitors; Practice Patterns, Physicians'; Prospective Studies; Risk Assessment; Ticlopidine; Time Factors | 2012 |
Sequential ADP-stimulated light transmission and multiple electrode aggregometry in patients taking aspirin and clopidogrel after non ST-elevation myocardial infarction.
Topics: Aged; Aspirin; Clopidogrel; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Reproducibility of Results; Ticlopidine | 2012 |
Treatment with aspirin or clopidogrel does not affect equine platelet expression of P selectin or platelet-neutrophil aggregates.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Clopidogrel; Cross-Over Studies; Female; Flow Cytometry; Horses; Male; Neutrophils; P-Selectin; Platelet Aggregation; Random Allocation; Statistics, Nonparametric; Ticlopidine | 2012 |
Combined clopidogrel and aspirin treatment up to surgery increases the risk of postoperative myocardial infarction, blood loss and reoperation for bleeding in patients undergoing coronary artery bypass grafting.
Topics: Aged; Aspirin; Blood Transfusion; Chi-Square Distribution; Clopidogrel; Coronary Artery Bypass; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Postoperative Complications; Postoperative Hemorrhage; Reoperation; Retrospective Studies; Statistics, Nonparametric; Ticlopidine; United Kingdom | 2013 |
Antiplatelet therapy prevents hepatocellular carcinoma and improves survival in a mouse model of chronic hepatitis B.
Topics: Analysis of Variance; Animals; Aspirin; Carcinoma, Hepatocellular; CD8-Positive T-Lymphocytes; Clopidogrel; Cyclooxygenase 1; Cyclooxygenase 2; Hepatitis B, Chronic; Liver; Liver Neoplasms; Membrane Proteins; Mice; Mice, Transgenic; Platelet Aggregation Inhibitors; Real-Time Polymerase Chain Reaction; Ticlopidine | 2012 |
Effect of different anticoagulants on multiple electrode platelet aggregometry after clopidogrel and aspirin administration in patients undergoing coronary stent implantation: a comparison between citrate and hirudin.
Topics: Adenosine Diphosphate; Aged; Analysis of Variance; Angioplasty, Balloon, Coronary; Anticoagulants; Arachidonic Acid; Aspirin; Citric Acid; Clopidogrel; Female; Hirudins; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Risk Factors; ROC Curve; Sensitivity and Specificity; Stents; Ticlopidine | 2013 |
Clopidogrel and interaction with proton pump inhibitors: comparison between cohort and within person study designs.
Topics: Aspirin; Clopidogrel; Cohort Studies; Data Collection; Drug Interactions; Humans; Multivariate Analysis; Myocardial Infarction; Platelet Aggregation Inhibitors; Proportional Hazards Models; Proton Pump Inhibitors; Research Design; Ticlopidine; Vascular Diseases | 2012 |
Prescribing proton pump inhibitors with clopidogrel.
Topics: Aspirin; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine | 2012 |
Perioperative management of a neurosurgical patient requiring antiplatelet therapy.
Topics: Aged; Aspirin; Cerebral Angiography; Clopidogrel; Humans; Intracranial Aneurysm; Intracranial Thrombosis; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Male; Neurologic Examination; Neurosurgical Procedures; Perioperative Care; Platelet Aggregation Inhibitors; Postoperative Complications; Stents; Ticlopidine; Tomography, X-Ray Computed; Ventriculoperitoneal Shunt | 2012 |
Atrial fibrillation and acute myocardial infarction: antithrombotic therapy and outcomes.
Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Comorbidity; Drug Therapy, Combination; Female; Fibrinolytic Agents; Hemorrhage; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Myocardial Infarction; Patient Discharge; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Research Design; Risk Assessment; Stroke; Thiophenes; Ticlopidine; Treatment Outcome; Warfarin | 2012 |
Antiplatelet therapy in acute coronary syndromes: beyond aspirin and clopidogrel.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Cyclooxygenase Inhibitors; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2012 |
Medium to long-term clinical outcomes with everolimus-eluting stents in real-life percutaneous coronary intervention.
Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Everolimus; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; New Zealand; Platelet Aggregation Inhibitors; Registries; Retrospective Studies; Sirolimus; Survival Analysis; Ticlopidine; Time Factors; Treatment Outcome | 2012 |
Combining aspirin and proton pump inhibitors: for whom the warning bell tolls?
Topics: Aspirin; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine | 2012 |
[CYP2C19 gene polymorphism in patients with myocardial infarction who use clopidogrel].
Topics: Aged; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Aspirin; Biotransformation; Clopidogrel; Coronary Angiography; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Stents; Ticlopidine; Treatment Outcome | 2012 |
[Comparison of three methods of antithrombotic therapy in elderly patients with nonvalvular atrial fibrillation].
Topics: Administration, Oral; Aged; Anticoagulants; Antithrombins; Aspirin; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Clopidogrel; Dabigatran; Drug Monitoring; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Platelet Aggregation Inhibitors; Stroke; Survival Rate; Ticlopidine; Treatment Outcome; Warfarin | 2012 |
Complex coronary lesions and rotational atherectomy: one hospital's experience.
Topics: Aged; Angiography; Aspirin; Atherectomy, Coronary; Cardiology; Clopidogrel; Comorbidity; Coronary Artery Disease; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Radiography, Interventional; Retrospective Studies; Ticlopidine; Treatment Outcome | 2012 |
[Removal of epidural catheter under dual antiplatelet therapy following acute coronary syndrome : scenario without special consideration to the current guidelines on epidural regional anesthesia].
Topics: Acute Coronary Syndrome; Analgesia, Epidural; Aspirin; Catheterization; Clopidogrel; Digestive System Surgical Procedures; Drug Interactions; Hemorrhage; Humans; Male; Middle Aged; Pain, Postoperative; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Risk; Thiophenes; Ticlopidine | 2012 |
Clopidogrel versus aspirin in patients with atherothrombosis: a CAPRIE-based cost-effectiveness model for Greece.
Topics: Aspirin; Atherosclerosis; Cardiovascular Diseases; Clopidogrel; Cost-Benefit Analysis; Greece; Humans; Models, Economic; Platelet Aggregation Inhibitors; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Secondary Prevention; Thrombosis; Ticlopidine; Treatment Outcome | 2012 |
One-year follow-up healthcare costs of patients hospitalized for transient ischemic attack or ischemic stroke and discharged with aspirin plus extended-release dipyridamole or clopidogrel.
Topics: Adolescent; Adult; Age Factors; Aged; Aspirin; Clopidogrel; Delayed-Action Preparations; Drug Therapy, Combination; Female; Health Care Costs; Health Expenditures; Health Services; Humans; Insurance Claim Review; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Sex Factors; Stroke; Ticlopidine; Young Adult | 2012 |
When coronary angiography is not enough to detect spontaneous left main coronary artery dissection.
Topics: Adrenergic beta-1 Receptor Antagonists; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aortic Dissection; Aspirin; Clopidogrel; Coronary Aneurysm; Coronary Angiography; Drug Therapy, Combination; Drug-Eluting Stents; Electrocardiography; Everolimus; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Metoprolol; Platelet Aggregation Inhibitors; Risk Factors; Sirolimus; Smoking; Ticlopidine; Treatment Outcome | 2012 |
Aspirin- and clopidogrel-associated bleeding complications: data mining of the public version of the FDA adverse event reporting system, AERS.
Topics: Adverse Drug Reaction Reporting Systems; Aspirin; Clopidogrel; Data Mining; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Ticlopidine; United States; United States Food and Drug Administration; Warfarin | 2012 |
Obesity and intracranial in-stent thrombosis.
Topics: Abciximab; Angioplasty, Balloon; Antibodies, Monoclonal; Aspirin; Body Mass Index; Brain Ischemia; Cerebral Angiography; Clopidogrel; Endovascular Procedures; Humans; Immunoglobulin Fab Fragments; Intracranial Thrombosis; Male; Middle Aged; Obesity, Morbid; Platelet Aggregation Inhibitors; Risk; Stents; Stroke; Ticlopidine | 2013 |
[Three case reports of the use of herbal combinations resulted in stent thrombosis: herbal combinations; friend or foe?].
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Avena; Chest Pain; Clopidogrel; Coronary Angiography; Coronary Vessels; Female; Humans; Male; Middle Aged; Panax; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine; Tribulus | 2012 |
Bleeding after initiation of multiple antithrombotic drugs, including triple therapy, in atrial fibrillation patients following myocardial infarction and coronary intervention: a nationwide cohort study.
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Atrial Fibrillation; Clopidogrel; Cohort Studies; Comorbidity; Denmark; Drug Therapy, Combination; Female; Fibrinolytic Agents; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Registries; Risk Factors; Stroke; Ticlopidine; Vitamin K | 2012 |
Impact of proton pump inhibitors or famotidine on the antiplatelet actions during dual-antiplatelet therapy in Japanese patients.
Topics: Aged; Asian People; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Interactions; Famotidine; Female; Histamine H2 Antagonists; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Proton Pump Inhibitors; Ticlopidine | 2013 |
Antiplatelet drugs in elective ENT surgery.
Topics: Aspirin; Blood Loss, Surgical; Clinical Protocols; Clopidogrel; Data Collection; Elective Surgical Procedures; Health Knowledge, Attitudes, Practice; Humans; Otolaryngology; Otorhinolaryngologic Surgical Procedures; Perioperative Care; Platelet Aggregation Inhibitors; Risk Factors; Stents; Thrombosis; Ticlopidine | 2012 |
Aspirin use and the risk of prostate cancer mortality in men treated with prostatectomy or radiotherapy.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Chemoprevention; Clopidogrel; Enoxaparin; Humans; Male; Middle Aged; Prostatectomy; Prostatic Neoplasms; Risk; Ticlopidine; Warfarin | 2012 |
Early and late outcome associated with bleeding events in the setting of dual antiplatelet therapy following stent placement.
Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug-Eluting Stents; Female; Hemorrhage; Humans; Male; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticlopidine | 2012 |
Less may be more: insights on dual antiplatelet therapy duration after drug-eluting stent implantation from the MATRIX registry.
Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug-Eluting Stents; Female; Humans; Male; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Tacrolimus; Ticlopidine | 2012 |
Clinical efficacy and safety of biodegradable polymer-based sirolimus-eluting stents in patients with diabetes mellitus insight from the 4-year results of the create study.
Topics: Absorbable Implants; Aged; Aspirin; Cardiovascular Agents; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Kaplan-Meier Estimate; Logistic Models; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Odds Ratio; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polymers; Prospective Studies; Prosthesis Design; Registries; Risk Assessment; Risk Factors; Sirolimus; Ticlopidine; Time Factors; Treatment Outcome | 2013 |
Evidence of net benefit of proton pump inhibitors with clopidogrel is lacking in older patients.
Topics: Aspirin; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine | 2012 |
Platelets in vascular disease.
Topics: Aspirin; Atherosclerosis; Blood Platelets; Clopidogrel; Hemostasis; Humans; Plaque, Atherosclerotic; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine; Vascular Diseases | 2013 |
Incidence of cerebral ischemic events after discontinuation of clopidogrel in patients with intracranial aneurysms treated with stent-assisted techniques.
Topics: Aged; Aged, 80 and over; Aspirin; Brain Ischemia; Clopidogrel; Cohort Studies; Drug Therapy, Combination; Embolization, Therapeutic; Female; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Male; Middle Aged; Neurosurgical Procedures; Platelet Aggregation Inhibitors; Retrospective Studies; Stents; Stroke; Subarachnoid Hemorrhage; Ticlopidine | 2012 |
Femoral pseudoaneurysm with a communicating arteriovenous fistula: a complication after percutaneous coronary intervention.
Topics: Aneurysm, False; Angioplasty, Balloon, Coronary; Arteriovenous Fistula; Aspirin; Clopidogrel; Comorbidity; Coronary Artery Disease; Drug Therapy, Combination; Femoral Artery; Fibrinolytic Agents; Humans; Male; Middle Aged; Ticlopidine; Treatment Outcome | 2012 |
Prescribing patterns of antiplatelet agents are highly variable after lower extremity endovascular procedures.
Topics: Anticoagulants; Aspirin; Clopidogrel; Drug Administration Schedule; Drug Prescriptions; Drug Therapy, Combination; Drug Utilization; Drug Utilization Review; Endovascular Procedures; Guideline Adherence; Health Care Surveys; Humans; Lower Extremity; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Practice Patterns, Physicians'; Stents; Surveys and Questionnaires; Ticlopidine; Time Factors; Warfarin | 2013 |
Prevalence of ex vivo high on-treatment platelet reactivity on antiplatelet therapy after transient ischemic attack or ischemic stroke on the PFA-100(®) and VerifyNow(®).
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Aspirin, Dipyridamole Drug Combination; Blood Platelets; Brain Ischemia; Clopidogrel; Cross-Sectional Studies; Dipyridamole; Drug Combinations; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Stroke; Ticlopidine | 2013 |
Effects of low-dose acetylsalicylic acid and atherosclerotic vascular diseases on the outcome in patients with severe sepsis or septic shock.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Atherosclerosis; Blood Coagulation; Clopidogrel; Female; Hospital Mortality; Humans; Intensive Care Units; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Sepsis; Shock, Septic; Ticlopidine; Treatment Outcome | 2013 |
[Surgery shortly after stent implantation?].
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Contraindications; Drug Interactions; Drug Therapy, Combination; Drug-Eluting Stents; Elective Surgical Procedures; Hernia, Inguinal; Herniorrhaphy; Humans; Male; Postoperative Hemorrhage; Risk Assessment; Ticlopidine | 2012 |
[General antithrombotic therapy practice facing fundamental change].
Topics: Aspirin; Cause of Death; Clopidogrel; Coronary Restenosis; Drug Therapy, Combination; Fibrinolytic Agents; Follow-Up Studies; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stents; Survival Rate; Ticlopidine | 2012 |
Secondary stroke prevention: misguided by guidelines?
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Retrospective Studies; Secondary Prevention; Stroke; Ticlopidine | 2012 |
Dual antiplatelet therapy after drug-eluting stent implantation: is it time to slacken the reins?
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Stenosis; Drug-Eluting Stents; Female; Humans; Male; Medication Adherence; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Sirolimus; Ticlopidine; Withholding Treatment | 2012 |
Double antiplatelet therapy after drug-eluting stent implantation: risk associated with discontinuation within the first year.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Male; Medication Adherence; Middle Aged; Platelet Aggregation Inhibitors; Prognosis; Retrospective Studies; Risk Factors; Spain; Survival Rate; Ticlopidine; Time Factors | 2012 |
Proton-pump inhibitors could be innocent when used concomitantly with clopidogrel.
Topics: Acute Coronary Syndrome; Anti-Ulcer Agents; Aspirin; Blood Platelets; Clopidogrel; Famotidine; Female; Humans; Male; Omeprazole; Platelet Aggregation Inhibitors; Ticlopidine | 2012 |
Successful resection of complicated bleeding arteriovenous malformation of the jejunum in patients starting dual-antiplatelet therapy just after implanting a drug-eluting coronary stent.
Topics: Arteriovenous Malformations; Aspirin; Clopidogrel; Drug-Eluting Stents; Gastrointestinal Hemorrhage; Humans; Jejunum; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Ticlopidine | 2012 |
Reversible shortness of breath caused by the antiplatelet agent, clopidogrel.
Topics: Aspirin; Cilostazol; Clopidogrel; Dyspnea; Embolization, Therapeutic; Endovascular Procedures; Humans; Intracranial Aneurysm; Male; Middle Aged; Platelet Aggregation Inhibitors; Stents; Tetrazoles; Ticlopidine | 2013 |
Treatment of blood blister-like aneurysms of the internal carotid artery with stent-assisted coil embolization.
Topics: Aspirin; Carotid Artery Diseases; Carotid Artery, Internal; Cerebral Angiography; Clopidogrel; Embolization, Therapeutic; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Recurrence; Retrospective Studies; Stents; Subarachnoid Hemorrhage; Ticlopidine; Tomography, X-Ray Computed; Treatment Outcome | 2013 |
Clopidogrel and cardiac surgery: enemy or friend?
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Coronary Artery Bypass, Off-Pump; Coronary Occlusion; Female; Humans; Male; Platelet Aggregation; Ticlopidine | 2012 |
Longitudinal assessment of thrombin generation potential in response to alteration of antiplatelet therapy after TIA or ischaemic stroke.
Topics: Adult; Aged; Aspirin; Clopidogrel; Dipyridamole; Female; Humans; Ischemic Attack, Transient; Longitudinal Studies; Male; Middle Aged; Pilot Projects; Platelet Aggregation Inhibitors; Statistics, Nonparametric; Stroke; Thrombin; Ticlopidine | 2013 |
Limitations of using cardiac catheterization rates to assess the quality of care for patients with non-ST-segment elevation myocardial infarction.
Topics: Adrenergic beta-1 Receptor Antagonists; Aged; Aged, 80 and over; Aspirin; Cardiac Catheterization; Clopidogrel; Comorbidity; Contraindications; Critical Pathways; Female; Guideline Adherence; Hospital Mortality; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Myocardial Infarction; Registries; Ticlopidine; United States | 2012 |
Antithrombotic therapy for atrial fibrillation and coronary artery disease in older patients.
Topics: Age Factors; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Diabetes Complications; Female; Fibrinolytic Agents; Heart Failure; Humans; Hypertension; Male; Risk Assessment; Stroke; Ticlopidine; Treatment Outcome; Warfarin | 2012 |
Dual antiplatelet agent-induced spontaneous liver hematoma.
Topics: Aged; Aspirin; Chemical and Drug Induced Liver Injury; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Hematoma; Humans; Male; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Ticlopidine | 2012 |
Comparison of outcomes in patients with head trauma, taking preinjury antithrombotic agents.
Topics: Aged; Aged, 80 and over; Aspirin; Australia; Clopidogrel; Craniocerebral Trauma; Drug Therapy, Combination; Emergency Service, Hospital; Female; Fibrinolytic Agents; Glasgow Coma Scale; Hospital Mortality; Humans; Intensive Care Units; Male; Outcome Assessment, Health Care; Prospective Studies; Ticlopidine; Warfarin | 2013 |
Effects of rivaroxaban, acetylsalicylic acid and clopidogrel as monotherapy and in combination in a porcine model of stent thrombosis.
Topics: Animals; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Morpholines; Platelet Aggregation; Rivaroxaban; Stents; Swine; Swine, Miniature; Thiophenes; Thrombosis; Ticlopidine | 2012 |
Triple antithrombotic therapy following an acute coronary syndrome: prevalence, outcomes and prognostic utility of the HAS-BLED score.
Topics: Acute Coronary Syndrome; Aged; Anticoagulants; Aspirin; Chi-Square Distribution; Clopidogrel; Comorbidity; Decision Support Techniques; Drug Therapy, Combination; Female; Fibrinolytic Agents; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Platelet Aggregation Inhibitors; Practice Patterns, Physicians'; Predictive Value of Tests; Retrospective Studies; Risk Assessment; Risk Factors; Sweden; Ticlopidine; Treatment Outcome; Warfarin | 2012 |
Monitoring residual platelet activity among patients with acute coronary syndrome.
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Reference Values; Ticlopidine | 2014 |
Oral anticoagulation and the risk of vitreous hemorrhage and retinal tears in eyes with acute posterior vitreous detachment.
Topics: Acute Disease; Administration, Oral; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Clopidogrel; Female; Humans; Male; Middle Aged; Retinal Detachment; Retinal Perforations; Retrospective Studies; Risk Assessment; Ticlopidine; Vitreous Detachment; Vitreous Hemorrhage; Warfarin | 2013 |
[Platelet inhibition in clinical practice].
Topics: Aged; Angioplasty, Balloon, Coronary; Arterial Occlusive Diseases; Aspirin; Cerebral Infarction; Clopidogrel; Coronary Artery Bypass; Drug Interactions; Drug Resistance; Drug Therapy, Combination; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Patient Compliance; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Transfusion; Risk Factors; Thrombosis; Ticlopidine | 2012 |
[Antiaggregation therapy after percutaneous coronary intervention in a patient with thrombocytopenia: case report].
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Stents; Thrombocytopenia; Ticlopidine | 2011 |
Statements of the Malaysian Society of Gastroenterology & Hepatology and the National Heart Association of Malaysia task force 2012 working party on the use of antiplatelet therapy and proton pump inhibitors in the prevention of gastrointestinal bleeding.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Gastrointestinal Hemorrhage; Humans; Malaysia; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine | 2013 |
Aspirin and clopidogrel alter core temperature and skin blood flow during heat stress.
Topics: Aged; Aspirin; Body Temperature Regulation; Clopidogrel; Cross-Over Studies; Double-Blind Method; Exercise Test; Female; Heat Stress Disorders; Humans; Laser-Doppler Flowmetry; Male; Middle Aged; Pennsylvania; Platelet Aggregation Inhibitors; Regional Blood Flow; Skin; Thermography; Ticlopidine | 2013 |
Lowering homocysteine levels may prevent cardiovascular impairments? Possible therapeutic behaviors.
Topics: Acetylcysteine; Aspirin; Blood Vessels; Cardiovascular Diseases; Clopidogrel; Diuretics; Fatty Acids, Omega-3; Folic Acid; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Metformin; Platelet Aggregation Inhibitors; S-Adenosylmethionine; Ticlopidine; Vitamin B 12; Vitamin B 6 | 2012 |
Postmenopausal women have an increased maximal platelet reactivity compared to men despite dual antiplatelet therapy.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Blood Platelets; Clopidogrel; Coronary Disease; Female; Humans; Male; Middle Aged; Peptide Fragments; Percutaneous Coronary Intervention; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Postmenopause; Prospective Studies; Sex Factors; Ticlopidine | 2012 |
Short-term effects of aspirin and clopidogrel on mean platelet volume among patients with acute coronary syndromes. A single-center prospective study.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Blood Platelets; Cell Size; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Prospective Studies; Ticlopidine; Treatment Outcome | 2012 |
[Current clinical practice among German Internists regarding the prophylaxis of gastroduodenal ulcers associated with NSAIDs, aspirin and Helicobacter pylori].
Topics: Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Clopidogrel; Coronary Disease; Cyclooxygenase 2 Inhibitors; Drug Substitution; Female; Germany; Health Surveys; Helicobacter Infections; Helicobacter pylori; Humans; Internal Medicine; Long-Term Care; Male; Middle Aged; Peptic Ulcer; Platelet Aggregation Inhibitors; Practice Patterns, Physicians'; Proton Pump Inhibitors; Surveys and Questionnaires; Ticlopidine | 2012 |
Treatment of a pediatric recurrent fusiform middle cerebral artery (MCA) aneurysm with a flow diverter.
Topics: Adolescent; Aspirin; Cerebral Angiography; Clopidogrel; Embolization, Therapeutic; Humans; Intracranial Aneurysm; Male; Platelet Aggregation Inhibitors; Recurrence; Ticlopidine | 2012 |
[Expert answer. Coronary artery patients with atrial fibrillation on anticoagulation treatment may need antithrombotic treatment. What kind is there?].
Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Ticlopidine; Warfarin | 2012 |
A new generation of biodegradable polymer-coated sirolimus-eluting stents for the treatment of coronary artery disease: final 5-year clinical outcomes from the CREATE study.
Topics: Absorbable Implants; Aged; Aspirin; Cardiovascular Agents; China; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Disease-Free Survival; Drug Therapy, Combination; Drug-Eluting Stents; Female; Heart Failure; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polymers; Propensity Score; Proportional Hazards Models; Prospective Studies; Prosthesis Design; Registries; Risk Assessment; Risk Factors; Sirolimus; Ticlopidine; Time Factors; Treatment Outcome | 2012 |
Clopidogrel and aspirin administration management prior to coronary artery surgery requires an individual approach.
Topics: Aspirin; Coronary Artery Bypass; Female; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Postoperative Complications; Ticlopidine | 2013 |
Long-term results of plaque excision combined with aggressive pharmacotherapy in high-risk patients with advanced peripheral artery disease (SAVE a LEG registry).
Topics: Adult; Aged; Aged, 80 and over; Amputation, Surgical; Aspirin; Atherectomy; Atorvastatin; Cardiovascular Agents; Clopidogrel; Combined Modality Therapy; Critical Illness; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Intermittent Claudication; Ischemia; Kaplan-Meier Estimate; Limb Salvage; Male; Middle Aged; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Pyrroles; Recurrence; Registries; Retrospective Studies; Risk Factors; Severity of Illness Index; Ticlopidine; Time Factors; Treatment Outcome | 2013 |
Analysing responses to aspirin and clopidogrel by measuring platelet thrombus formation under arterial flow conditions.
Topics: Adult; Aged; Area Under Curve; Arteries; Aspirin; Automation, Laboratory; Blood Platelets; Capillaries; Case-Control Studies; Clopidogrel; Drug Therapy, Combination; Female; Flow Cytometry; Humans; Male; Microchip Analytical Procedures; Middle Aged; Monocytes; P-Selectin; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Regional Blood Flow; ROC Curve; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2013 |
Resistance to clopidogrel: prevalence and associate variables.
Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation; Platelet Aggregation Inhibitors; Retrospective Studies; Stents; Ticlopidine; Treatment Outcome | 2012 |
Safety of endoscopic sphincterotomy in patients under dual antiplatelet therapy.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cholangiopancreatography, Endoscopic Retrograde; Clopidogrel; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Patient Safety; Platelet Aggregation Inhibitors; Retrospective Studies; Sphincterotomy, Endoscopic; Ticlopidine; Time Factors; Treatment Outcome | 2013 |
Clopidogrel resistance is associated with thromboembolic complications in patients undergoing neurovascular stenting.
Topics: Aged; Aspirin; Blood Platelets; Cerebral Arteries; Clopidogrel; Dose-Response Relationship, Drug; Drug Resistance; Endovascular Procedures; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Retrospective Studies; Stents; Thromboembolism; Ticlopidine | 2013 |
Pharmaceutical care for patients with acute myocardial infarction in Hungary.
Topics: Acute Disease; Adult; Aged; Aspirin; Clopidogrel; Comorbidity; Diabetes Mellitus; Drug Therapy, Combination; Female; Humans; Hungary; Incidence; Male; Middle Aged; Muscle Hypotonia; Myocardial Infarction; Platelet Aggregation Inhibitors; Retrospective Studies; Risk; Secondary Prevention; Ticlopidine; Treatment Outcome; Young Adult | 2013 |
The effect of Neuroform stent-assisted coil embolization of wide-necked intracranial aneurysms and clinical factors on progressive aneurysm occlusion on angiographic follow-up.
Topics: Adult; Aspirin; Cerebral Angiography; Clopidogrel; Disease Progression; Embolization, Therapeutic; Female; Follow-Up Studies; Humans; Intracranial Aneurysm; Male; Middle Aged; Retrospective Studies; Stents; Ticlopidine; Treatment Outcome | 2013 |
The assessment of risk for gastrointestinal injury with anticoagulant and antiplatelet drugs: the possible beneficial effect of eicosapentaenoic Acid for the risk of gastrointestinal injury.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Clopidogrel; Eicosapentaenoic Acid; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Protective Agents; Retrospective Studies; Risk Assessment; Ticlopidine; Warfarin | 2013 |
Continued concern about parent vessel steno-occlusive progression with Onyx HD-500 and the utility of quantitative magnetic resonance imaging in serial assessment.
Topics: Angioplasty; Aspirin; Carotid Artery Diseases; Carotid Stenosis; Clopidogrel; Constriction, Pathologic; Databases, Factual; Disease Progression; Embolization, Therapeutic; Humans; Intracranial Aneurysm; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Platelet Aggregation Inhibitors; Postoperative Complications; Retrospective Studies; Stents; Ticlopidine; Treatment Outcome | 2013 |
Deliverability of integrity coronary stents in severely tortuous coronary arteries: a preliminary experience.
Topics: Aged; Aspirin; Clopidogrel; Coronary Angiography; Coronary Stenosis; Coronary Vessels; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Retrospective Studies; Stents; Ticlopidine; Treatment Outcome | 2012 |
Dual antiplatelet therapy in peripheral arterial disease and after peripheral percutaneous revascularization.
Topics: Aspirin; Clopidogrel; Endovascular Procedures; Hemorrhage; Humans; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Stents; Stroke; Ticlopidine; Treatment Outcome | 2012 |
Current antiplatelet therapy for Japanese patients with ST elevation acute myocardial infarction: J-AMI registry.
Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Coronary Thrombosis; Drug Therapy, Combination; Female; Humans; Incidence; Japan; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Preoperative Care; Prospective Studies; Registries; Risk Factors; Stents; Ticlopidine; Treatment Outcome | 2013 |
Hospital case volume and appropriate prescriptions at hospital discharge after acute myocardial infarction: a nationwide assessment.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; France; Hospitals, High-Volume; Hospitals, Low-Volume; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Myocardial Infarction; Patient Discharge; Prescriptions; Quality Assurance, Health Care; Quality Indicators, Health Care; Retrospective Studies; Ticlopidine | 2013 |
Therapeutic momentum: a concept opposite to therapeutic inertia.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Cross-Sectional Studies; Humans; Platelet Aggregation Inhibitors; Practice Patterns, Physicians'; Sri Lanka; Ticlopidine; Unnecessary Procedures; Withholding Treatment | 2013 |
"Why did my CPAP beat me up?" Bilateral periorbital ecchymosis associated with continuous positive airway pressure therapy.
Topics: Aspirin; Clopidogrel; Continuous Positive Airway Pressure; Dietary Supplements; Ecchymosis; Fish Oils; Humans; Male; Middle Aged; Orbital Diseases; Platelet Aggregation Inhibitors; Sleep Apnea, Obstructive; Ticlopidine; Vitamin E | 2012 |
Evaluation of the pharmacokinetics and pharmacodynamics of ticagrelor co-administered with aspirin in healthy volunteers.
Topics: Adenosine; Adenosine Diphosphate; Adult; Aspirin; Bleeding Time; Clopidogrel; Collagen; Drug Therapy, Combination; Female; Healthy Volunteers; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticagrelor; Ticlopidine; Young Adult | 2013 |
Assessment of high on-treatment platelet reactivity in patients with ischemic heart disease: concordance between the Multiplate and VerifyNow assays.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Blood Platelets; Clopidogrel; Drug Resistance; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Reproducibility of Results; Spain; Ticlopidine; Treatment Outcome | 2013 |
Antiplatelet therapy in ischemic stroke: does one size fit all?
Topics: Aspirin; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2012 |
Spontaneous spinal epidural haematoma after antiplatelet treatment: a report of two cases.
Topics: Aged; Aspirin; Clopidogrel; Decompression, Surgical; Female; Hematoma, Epidural, Spinal; Humans; Laminectomy; Magnetic Resonance Imaging; Male; Middle Aged; Platelet Aggregation Inhibitors; Spinal Fusion; Ticlopidine | 2012 |
Upper gastrointestinal lesions in patients receiving clopidogrel anti-platelet therapy.
Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Endoscopy, Gastrointestinal; Female; Gastrointestinal Hemorrhage; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Peptic Ulcer; Platelet Aggregation Inhibitors; Prospective Studies; Smoking; Ticlopidine | 2012 |
Friend or foe? Discussion about dual platelet inhibition as a salvage procedure from imminent flap failure.
Topics: Aspirin; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Mammaplasty; Middle Aged; No-Reflow Phenomenon; Platelet Aggregation Inhibitors; Postoperative Complications; Salvage Therapy; Surgical Flaps; Ticlopidine | 2013 |
Safety of reloading prasugrel in addition to clopidogrel loading in patients with acute coronary syndrome undergoing percutaneous coronary intervention.
Topics: Acute Coronary Syndrome; Aspirin; Chi-Square Distribution; Clopidogrel; Endpoint Determination; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Risk Factors; Statistics, Nonparametric; Thiophenes; Ticlopidine; Treatment Outcome | 2013 |
Triple antiplatelet therapy with cilostazol: hitting the "sweet-spot".
Topics: Aspirin; Blood Platelets; Cilostazol; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Tetrazoles; Ticlopidine | 2013 |
Decreased plasma IL-35 levels are related to the left ventricular ejection fraction in coronary artery diseases.
Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Cytokines; Female; Humans; Interleukins; Male; Middle Aged; Statistics, Nonparametric; Stroke Volume; Ticlopidine | 2012 |
Historical lessons in translational medicine: cyclooxygenase inhibition and P2Y12 antagonism.
Topics: Animals; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Discovery; Drug Resistance; Evidence-Based Medicine; History, 20th Century; History, 21st Century; Humans; Pharmacogenetics; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Ticlopidine; Translational Research, Biomedical | 2013 |
[Correlation between antiplatelet resistance and recurrent cardiac ischemic events of patients with acute myocardial infarction].
Topics: Aged; Aspirin; Clopidogrel; Drug Resistance; Electric Impedance; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Recurrence; Ticlopidine | 2012 |
Clopidogrel has no effect on mortality from hip fracture.
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Aspirin; Blood Loss, Surgical; Blood Transfusion; Clopidogrel; Female; Hip Fractures; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Practice Patterns, Physicians'; Severity of Illness Index; Stroke; Ticlopidine; Time Factors; Treatment Outcome; United Kingdom | 2013 |
A huge coronary artery aneurysm in osteogenesis imperfecta: a case report.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Coronary Aneurysm; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypotension; Inferior Wall Myocardial Infarction; Osteogenesis Imperfecta; Platelet Aggregation Inhibitors; Rare Diseases; Ticlopidine; Treatment Outcome; Ultrasonography | 2012 |
Benefit of low-dose aspirin and non-steroidal anti-inflammatory drugs in septic patients.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Female; Hospital Mortality; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intensive Care Units; Length of Stay; Male; Middle Aged; Platelet Aggregation Inhibitors; Sepsis; Ticlopidine | 2013 |
Human platelet protease-activated receptor-1 responsiveness to thrombin related to P2Y12 inhibition.
Topics: Adenosine Diphosphate; Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Models, Cardiovascular; Platelet Activation; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Receptor, PAR-1; Receptors, Purinergic P2Y12; Thrombin; Thromboembolism; Ticlopidine; Translational Research, Biomedical | 2013 |
Risk factors for upper gastrointestinal bleeding in coronary artery disease patients receiving both aspirin and clopidogrel.
Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Coronary Artery Disease; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Proportional Hazards Models; Retrospective Studies; Risk Factors; Ticlopidine; Upper Gastrointestinal Tract | 2013 |
The impact of triple anti-platelet therapy for endothelialization and inflammatory response at overlapping bioabsorbable polymer coated drug-eluting stents in a porcine coronary model.
Topics: Absorbable Implants; Animals; Aspirin; Cilostazol; Clopidogrel; Coated Materials, Biocompatible; Coronary Restenosis; Coronary Vessels; Disease Models, Animal; Drug Therapy, Combination; Drug-Eluting Stents; Female; Inflammation; Neointima; Platelet Aggregation Inhibitors; Polymers; Swine; Tetrazoles; Ticlopidine; Treatment Outcome | 2013 |
Characterization of aspirin allergies in patients with coronary artery disease.
Topics: Aged; Aged, 80 and over; Aspirin; California; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Drug Hypersensitivity; Female; Humans; Male; Retrospective Studies; Ticlopidine | 2013 |
Reversible cerebral vasoconstriction syndrome and bilateral vertebral artery dissection presenting in a patient after cesarean section.
Topics: Aspirin; Cerebral Angiography; Cesarean Section; Clopidogrel; Female; Headache; Humans; Magnetic Resonance Imaging; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Syndrome; Ticlopidine; Tomography, X-Ray Computed; Vasoconstriction; Vasospasm, Intracranial; Vertebral Artery Dissection | 2013 |
Acute myocardial infarction and heart block: a challenge to emergency physicians.
Topics: Aspirin; Clopidogrel; Electrocardiography; Enoxaparin; Fibrinolytic Agents; Heart Block; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Thrombolytic Therapy; Ticlopidine | 2013 |
Thrombocytopenia induced by both aspirin and clopidogrel in the same patient.
Topics: Aged; Aspirin; Clopidogrel; Female; Humans; Platelet Aggregation Inhibitors; Thrombocytopenia; Ticlopidine | 2013 |
Cerebroprotective effect of preoperative dual antiplatelet therapy in patients undergoing coronary bypass surgery.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cardiopulmonary Bypass; Clopidogrel; Cognition; Cognition Disorders; Coronary Artery Bypass; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Platelet Aggregation Inhibitors; Predictive Value of Tests; Principal Component Analysis; Ticlopidine; Time Factors; Treatment Outcome | 2014 |
Unclassified pleomorphic and spindle cell pulmonary neoplasm with brain metastases after prasugrel.
Topics: Aged; Aspirin; Brain Neoplasms; Carcinoma; Clinical Trials, Phase III as Topic; Clopidogrel; Colonic Neoplasms; Coronary Stenosis; Diabetes Mellitus, Type 1; Diabetic Cardiomyopathies; Drug Therapy, Combination; Drug-Eluting Stents; Fatal Outcome; Female; Humans; Lung Neoplasms; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Randomized Controlled Trials as Topic; Risk Factors; Thiophenes; Ticlopidine; Time Factors | 2013 |
A case of in-stent thrombosis in a patient with drug eluting stents during perioperative management with glycoprotein IIb/IIIa inhibitors.
Topics: Aged; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Thrombosis; Drug Substitution; Drug Therapy, Combination; Drug-Eluting Stents; Eptifibatide; Female; Humans; Neurosurgical Procedures; Peptides; Percutaneous Coronary Intervention; Perioperative Period; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine; Time Factors; Treatment Outcome; Ultrasonography, Interventional | 2013 |
Influence of oral antiplatelet therapy on hemorrhagic complications of pacemaker implantation.
Topics: Administration, Oral; Aged; Aspirin; Biomarkers; Blood Transfusion; Cardiac Pacing, Artificial; Clopidogrel; Drug Therapy, Combination; Female; Germany; Hematoma; Hemoglobins; Humans; Incidence; Logistic Models; Male; Middle Aged; Odds Ratio; Pacemaker, Artificial; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Retrospective Studies; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome | 2013 |
The use of flow diverter stents in the management of traumatic vertebral artery dissections.
Topics: Accidental Falls; Aged; Angiography; Anticoagulants; Aspirin; Clopidogrel; Endovascular Procedures; Heparin; Humans; Platelet Aggregation Inhibitors; Regional Blood Flow; Stents; Ticlopidine; Tomography, X-Ray Computed; Treatment Outcome; Vertebral Artery Dissection | 2013 |
Amplatzer left atrial appendage occlusion: single center 10-year experience.
Topics: Aged; Aged, 80 and over; Anesthesia, Local; Aspirin; Atrial Appendage; Atrial Fibrillation; Cardiac Catheterization; Clopidogrel; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Radiography, Interventional; Retrospective Studies; Stroke; Switzerland; Ticlopidine; Time Factors; Treatment Outcome | 2013 |
Dual or single antiplatelet therapy with anticoagulation?
Topics: Anticoagulants; Aspirin; Clopidogrel; Female; Humans; Male; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticlopidine | 2013 |
High-dose aspirin in dogs increases vascular resistance with limited additional anti-platelet effect when combined with potent P2Y12 inhibition.
Topics: Adenosine; Animals; Arachidonic Acid; Aspirin; Clopidogrel; Dogs; Dose-Response Relationship, Drug; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Thrombosis; Ticagrelor; Ticlopidine; Vascular Resistance | 2013 |
[3-year follow-up after endovascular aneurysm treatment with Silk® flow diverter].
Topics: Adult; Aged; Aspirin; Cerebral Angiography; Clopidogrel; Embolization, Therapeutic; Equipment Design; Female; Humans; Intracranial Aneurysm; Magnetic Resonance Angiography; Male; Middle Aged; Platelet Aggregation Inhibitors; Premedication; Recurrence; Retreatment; Stents; Surgical Instruments; Ticlopidine; Tomography, X-Ray Computed | 2013 |
SILK flow diverter for treatment of intracranial aneurysms: initial experience and cost analysis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Aspirin; Clopidogrel; Coronary Angiography; Costs and Cost Analysis; Databases, Factual; Dexamethasone; Embolization, Therapeutic; Female; Follow-Up Studies; Humans; Intracranial Aneurysm; Magnetic Resonance Angiography; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Stents; Ticlopidine; Tomography, X-Ray Computed; Treatment Outcome; Young Adult | 2013 |
Cardiac magnetic resonance detection of left ventricular thrombus in acute myocardial infarction.
Topics: Aged; Anticoagulants; Aspirin; Clopidogrel; Cohort Studies; Drug Therapy, Combination; Echocardiography; Female; Humans; Incidence; Magnetic Resonance Imaging, Cine; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prospective Studies; Stroke Volume; Thrombosis; Ticlopidine; Ventricular Dysfunction, Left; Warfarin | 2013 |
Duration of dual antiplatelet therapy after implantation of the first-generation and second-generation drug-eluting stents.
Topics: Aged; Aspirin; Cardiovascular Agents; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Disease-Free Survival; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proportional Hazards Models; Prosthesis Design; Retrospective Studies; Risk Assessment; Risk Factors; Sirolimus; Stroke; Ticlopidine; Time Factors; Treatment Outcome | 2013 |
PCI patients taking oral anticoagulants may not need aspirin.
Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Atrial Flutter; Clopidogrel; Drug Therapy, Combination; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Ticlopidine; Treatment Outcome | 2013 |
[Is antiplatelet therapy always effective?].
Topics: Adult; Aspirin; Cardiovascular Diseases; Clopidogrel; Humans; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine; Treatment Outcome | 2012 |
Cilostazol for primary prevention of stroke in peripheral artery disease: a population-based longitudinal study in Taiwan.
Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Cohort Studies; Female; Humans; Longitudinal Studies; Male; Peripheral Arterial Disease; Retrospective Studies; Risk Factors; Stroke; Taiwan; Tetrazoles; Ticlopidine; Vasodilator Agents | 2013 |
Invited commentary.
Topics: Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Humans; Male; Ticlopidine; Tranexamic Acid | 2013 |
Comparative effect of clopidogrel plus aspirin and aspirin monotherapy on hematological parameters using propensity score matching.
Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Erythrocyte Count; Female; Hematocrit; Hemoglobins; Humans; Leukocyte Count; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Count; Propensity Score; Risk Factors; Ticlopidine; Treatment Outcome | 2013 |
A Boolean view separates platelet activatory and inhibitory signalling as verified by phosphorylation monitoring including threshold behaviour and integrin modulation.
Topics: Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Hemorrhage; Humans; Iloprost; Integrins; Milrinone; Models, Biological; Molecular Dynamics Simulation; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Proto-Oncogene Proteins c-akt; Signal Transduction; Ticlopidine | 2013 |
Thrombocytopenia, dual antiplatelet therapy, and heparin bridging strategy increase pocket hematoma complications in patients undergoing cardiac rhythm device implantation.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; China; Clopidogrel; Cross-Sectional Studies; Defibrillators, Implantable; Drug Therapy, Combination; Female; Hematoma; Heparin; Humans; Incidence; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Retrospective Studies; Risk Factors; Thrombocytopenia; Ticlopidine; Warfarin | 2013 |
Ask the doctor. I need surgery for a gastrointestinal problem, and my question is how to handle my antiplatelet therapy, which I have been taking for two years since I had angioplasty. I take aspirin and clopidogrel, which were started after I had a hea
Topics: Aspirin; Clopidogrel; Contraindications; Digestive System Surgical Procedures; Dose-Response Relationship, Drug; Gastrointestinal Diseases; Humans; Platelet Aggregation Inhibitors; Preoperative Care; Stents; Ticlopidine; Withholding Treatment | 2012 |
Low prevalence of clopidogrel and acetylsalicylic acid resistance in patients with acute myocardial infarction and pantoprazole treatment in everyday practice.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Female; Follow-Up Studies; General Practice; Humans; Male; Middle Aged; Myocardial Infarction; Pantoprazole; Platelet Aggregation Inhibitors; Prevalence; Ticlopidine; Treatment Outcome | 2013 |
[Aneurysm of abdominal aorta rupture in a patient on dabigatran treatment].
Topics: Aged; Antithrombins; Aortic Aneurysm, Abdominal; Aortic Rupture; Arrhythmias, Cardiac; Aspirin; Benzimidazoles; beta-Alanine; Blood Transfusion, Autologous; Clopidogrel; Dabigatran; Humans; Male; Plasma; Platelet Aggregation Inhibitors; Platelet Transfusion; Shock, Hemorrhagic; Ticlopidine | 2013 |
Hypertension as a risk factor for aspirin and clopidogrel resistance in patients with stable coronary artery disease.
Topics: Adult; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Resistance; Female; Humans; Hypertension; Male; Mean Platelet Volume; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Count; Risk Factors; Stents; Ticlopidine | 2014 |
Quantitative assessment of late lumen loss after biodegradable polymer and permanent polymer sirolimus-eluting stents implantation.
Topics: Aged; Aspirin; Clopidogrel; Coronary Restenosis; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Polymers; Regression Analysis; Sirolimus; Ticlopidine | 2013 |
Triple therapy with aspirin, prasugrel, and vitamin K antagonists in patients with drug-eluting stent implantation and an indication for oral anticoagulation.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Clopidogrel; Cohort Studies; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Patient Selection; Percutaneous Coronary Intervention; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Thiophenes; Ticlopidine; Vitamin K | 2013 |
Safety and efficacy of intense antithrombotic treatment and percutaneous coronary intervention deferral in patients with large intracoronary thrombus.
Topics: Acute Coronary Syndrome; Angiography; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Cohort Studies; Coronary Thrombosis; Enoxaparin; Humans; Inpatients; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prospective Studies; Thrombectomy; Thrombolytic Therapy; Ticlopidine | 2013 |
The effect of fibrin clot inhibitors on the immunomodulatory efficacy of Bacillus Calmette-Guérin therapy for non-muscle-invasive bladder cancer.
Topics: Adjuvants, Immunologic; Aged; Aged, 80 and over; Anticoagulants; Aspirin; BCG Vaccine; Clopidogrel; Disease Progression; Disease-Free Survival; Female; Follow-Up Studies; Humans; Immunomodulation; Induction Chemotherapy; Kaplan-Meier Estimate; Logistic Models; Male; Middle Aged; Multivariate Analysis; Neoplasm Recurrence, Local; Odds Ratio; Proportional Hazards Models; Retrospective Studies; Ticlopidine; Urinary Bladder Neoplasms; Warfarin | 2013 |
[Assessment of clinical and antiaggregation efficacy of generic clopidogrel 'Egithromb' in roentgenosurgical practice].
Topics: Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Restenosis; Dose-Response Relationship, Drug; Drug Resistance; Drugs, Generic; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Therapeutic Equivalency; Ticlopidine; Treatment Outcome | 2013 |
Assaying the efficacy of dual-antiplatelet therapy: use of a controlled-shear-rate microfluidic device with a well-defined collagen surface to track dynamic platelet adhesion.
Topics: Aspirin; Biological Assay; Blood Platelets; Cells, Cultured; Clopidogrel; Collagen; Dose-Response Relationship, Drug; Drug Combinations; Drug Evaluation, Preclinical; Flow Injection Analysis; Humans; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Shear Strength; Surface Properties; Ticlopidine; Treatment Outcome | 2013 |
Intractable intraoperative bleeding requiring platelet transfusion during emergent cholecystectomy in a patient with dual antiplatelet therapy after drug-eluting coronary stent implantation (with video).
Topics: Aged; Aspirin; Blood Loss, Surgical; Cholecystectomy; Coronary Artery Disease; Drug-Eluting Stents; Emergency Treatment; Humans; Intraoperative Complications; Male; Platelet Aggregation Inhibitors; Platelet Transfusion; Ticlopidine | 2013 |
Lifetime cost-effectiveness analysis of ticagrelor in patients with acute coronary syndromes based on the PLATO trial: a Singapore healthcare perspective.
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Clinical Trials as Topic; Clopidogrel; Cost-Benefit Analysis; Decision Trees; Drug Costs; Humans; Markov Chains; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Quality-Adjusted Life Years; Republic of Korea; Singapore; Ticagrelor; Ticlopidine | 2013 |
Spontaneous hematomas.
Topics: Aspirin; Clopidogrel; Disseminated Intravascular Coagulation; Drug Therapy, Combination; Hematoma; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine | 2013 |
[Effect of intracoronary and intravenous administration of tirofiban loading dose in patients underwent percutaneous coronary interventions because of acute coronary syndrome].
Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Monitoring; Electrocardiography; Female; Hemorrhage; Humans; Length of Stay; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Preoperative Care; Retrospective Studies; Survival Analysis; Ticlopidine; Tirofiban; Treatment Outcome; Tyrosine | 2013 |
Soluble P-selectin level correlates with acetylsalicylic acid but not with clopidogrel response in patients with stable coronary artery disease after a percutaneous coronary intervention.
Topics: Aged; Anti-Inflammatory Agents; Aryl Hydrocarbon Hydroxylases; Aspirin; CD40 Ligand; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Microfilament Proteins; Middle Aged; P-Selectin; Percutaneous Coronary Intervention; Phosphoproteins; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2013 |
Prophylactic effect of egualen sodium, a stable azulene derivative, on gastrointestinal damage induced by ischemia/reperfusion, double antiplatelet therapy and loxoprofen in rats.
Topics: Animals; Aspirin; Azulenes; Benzoquinones; Clopidogrel; Gastric Mucosa; Gastrointestinal Hemorrhage; Gastrointestinal Tract; Heptanoic Acids; Male; Mice; Mice, Inbred C57BL; Mucus; Nitric Oxide Synthase Type II; Peptic Ulcer; Peroxidase; Phenylpropionates; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sesquiterpenes; Ticlopidine | 2013 |
Influence of genetic polymorphisms on platelet function, response to antiplatelet drugs and clinical outcomes in patients with coronary artery disease.
Topics: Adenosine; Aryl Hydrocarbon Hydroxylases; Aryldialkylphosphatase; Aspirin; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Humans; Pharmacogenetics; Piperazines; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Thiophenes; Ticagrelor; Ticlopidine | 2013 |
Bleeding complications during percutaneous coronary intervention.
Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Aspirin; Clopidogrel; Hemorrhage; Heparin; Heparin, Low-Molecular-Weight; Hirudins; Humans; Immunoglobulin Fab Fragments; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Recombinant Proteins; Ticlopidine | 2004 |
Using Leo Plus stent as flow diverter and endoluminal remodeling in endovascular treatment of intracranial fusiform aneurysms.
Topics: Adult; Aged; Anesthesia, General; Aneurysm; Angiography, Digital Subtraction; Aspirin; Blepharoptosis; Cerebral Angiography; Clopidogrel; Diplopia; Endovascular Procedures; Feasibility Studies; Female; Headache; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Male; Middle Aged; Neurologic Examination; Platelet Aggregation Inhibitors; Posterior Cerebral Artery; Retrospective Studies; Stents; Ticlopidine; Tomography, X-Ray Computed; Treatment Outcome | 2013 |
Ticagrelor improves peripheral arterial function in patients with a previous acute coronary syndrome.
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Blood Pressure; Case-Control Studies; Clopidogrel; Endothelium, Vascular; Female; Glomerular Filtration Rate; Humans; Male; Middle Aged; Peripheral Arterial Disease; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Thiophenes; Ticagrelor; Ticlopidine; Treatment Outcome | 2013 |
[Influence of the combination of antiplatelet agents on the occurrence of early left ventricular insufficiency in patients with acute coronary syndromes without persistent ST-segment elevation].
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Risk Factors; Ticlopidine; Tirofiban; Treatment Outcome; Tyrosine; Ventricular Dysfunction, Left | 2014 |
Association of PON1 genotype and haplotype with susceptibility to coronary artery disease and clinical outcomes in dual antiplatelet-treated Han Chinese patients.
Topics: Aged; Aryldialkylphosphatase; Asian People; Aspirin; Clopidogrel; Coronary Artery Disease; Female; Genetic Predisposition to Disease; Genotype; Haplotypes; Humans; Logistic Models; Male; Middle Aged; Platelet Aggregation Inhibitors; Promoter Regions, Genetic; Ticlopidine; Treatment Outcome | 2013 |
Is platelet transfusion efficient to restore platelet reactivity in patients who are responders to aspirin and/or clopidogrel before emergency surgery?
Topics: Aspirin; Blood Platelets; Clopidogrel; Hemorrhage; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Transfusion; Prospective Studies; Ticlopidine; Wounds and Injuries | 2013 |
Preserved thrombin-inducible platelet activation in thienopyridine-treated patients.
Topics: Adenosine Diphosphate; Aged; Angioplasty; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Female; Humans; Integrin beta3; Male; Middle Aged; P-Selectin; Peptide Fragments; Piperazines; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoprotein IIb; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Stents; Thiophenes; Thrombin; Ticlopidine | 2013 |
Cytochrome P450 2B6 and 2C9 genotype polymorphism--a possible cause of prasugrel low responsiveness.
Topics: Aryl Hydrocarbon Hydroxylases; Aspirin; Biomarkers, Pharmacological; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C9; Drug Resistance; Drug Therapy, Combination; Female; Gene Frequency; Genetic Association Studies; Genotype; Humans; Male; Middle Aged; Piperazines; Polymorphism, Genetic; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Thiophenes; Ticlopidine | 2013 |
Response to antiplatelet therapy is independent of endogenous thrombin generation potential.
Topics: Aged; Angioplasty; Aspirin; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Female; Humans; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Thrombin; Ticlopidine | 2013 |
A coronary pseudoaneurysm within a restenotic stent treated by implantation of a pericardium-covered stent and drug-eluting balloon.
Topics: Aneurysm, False; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Restenosis; Coronary Vessels; Drug Therapy, Combination; Female; Humans; Middle Aged; Paclitaxel; Pericardium; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Treatment Outcome | 2013 |
Aspirin desensitisation for Chinese patients with coronary artery disease.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Desensitization, Immunologic; Drug Hypersensitivity; Drug-Eluting Stents; Female; Hong Kong; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Stents; Ticlopidine; Time Factors | 2013 |
Safety and effectiveness of Thulium VapoEnucleation of the prostate (ThuVEP) in patients on anticoagulant therapy.
Topics: Administration, Oral; Aged; Anticoagulants; Aspirin; Clopidogrel; Hemorrhage; Humans; Incidence; Male; Minimally Invasive Surgical Procedures; Prostatectomy; Prostatic Hyperplasia; Retrospective Studies; Thulium; Ticlopidine; Treatment Outcome; Urinary Tract Infections; Venous Thrombosis | 2014 |
Relationship between aspirin/clopidogrel resistance and intra-stent thrombi assessed by follow-up optical coherence tomography after drug-eluting stent implantation.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Cohort Studies; Confidence Intervals; Coronary Angiography; Coronary Thrombosis; Drug Resistance; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Platelet Aggregation Inhibitors; Prosthesis Failure; Retrospective Studies; Risk Assessment; Severity of Illness Index; Thrombosis; Ticlopidine; Tomography, Optical Coherence; Treatment Outcome | 2013 |
Antiplatelet therapy at the time of coronary artery bypass grafting: a multicentre cohort study.
Topics: Aged; Analysis of Variance; Aspirin; Blood Transfusion; Clopidogrel; Cohort Studies; Coronary Artery Bypass; Denmark; Female; Hospitals, University; Humans; Male; Middle Aged; Odds Ratio; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Reoperation; Thrombosis; Ticlopidine | 2013 |
CYP2C19 genotypes and their impact on clopidogrel responsiveness in percutaneous coronary intervention.
Topics: Adult; Aged; Alleles; Aryl Hydrocarbon Hydroxylases; Asian People; Aspirin; Clopidogrel; Cytochrome P-450 CYP2C19; Female; Follow-Up Studies; Genotype; Humans; Malaysia; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Prevalence; Ticlopidine; Treatment Outcome | 2013 |
Spontaneous platelet aggregation in patients with acute coronary syndrome.
Topics: Acute Coronary Syndrome; Alprostadil; Antibodies; Aspirin; Blood Platelets; Clopidogrel; Humans; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIb-IX Complex; Ticlopidine; von Willebrand Factor | 2013 |
Proton-pump inhibitors can decrease gastrointestinal bleeding after percutaneous coronary intervention.
Topics: Acute Coronary Syndrome; Age Factors; Aged; Alcohol Drinking; Angina, Stable; Aspirin; Case-Control Studies; Clopidogrel; Female; Gastrointestinal Hemorrhage; Humans; Male; Peptic Ulcer; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Retrospective Studies; Risk Factors; Sex Factors; Smoking; Ticlopidine | 2013 |
Perioperative management of a neurosurgical patient with a meningioma and recent coronary artery stent.
Topics: Aged; Aspirin; Blood Loss, Surgical; Clopidogrel; Contraindications; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Meningioma; Perioperative Care; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine | 2013 |
Management of antithrombotic agents for colonoscopic polypectomies in Israeli gastroenterologists relative to published guidelines.
Topics: Aspirin; Clopidogrel; Colonic Polyps; Colonoscopy; Fibrinolytic Agents; Gastroenterology; Guideline Adherence; Health Maintenance Organizations; Heparin, Low-Molecular-Weight; Hospitals; Humans; Israel; Logistic Models; Practice Guidelines as Topic; Practice Patterns, Physicians'; Surveys and Questionnaires; Ticlopidine; Warfarin | 2013 |
Pathways of platelet activation and unexplained clopidogel variability: causes of poor response to clopidogrel.
Topics: Aspirin; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2013 |
Triple antiplatelet therapy with addition of cilostazol to aspirin and clopidogrel for Y-stent-assisted coil embolization of cerebral aneurysms.
Topics: Adult; Aged; Aspirin; Cilostazol; Clopidogrel; Drug Therapy, Combination; Embolization, Therapeutic; Female; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Stents; Tetrazoles; Ticlopidine | 2013 |
[Rapid aspirin desensitization in patients with a history of aspirin hypersensitivity requiring coronary angioplasty. Report of four cases].
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Desensitization, Immunologic; Drug Hypersensitivity; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2013 |
Anti-platelet therapy in the prevention of hepatitis B virus-associated hepatocellular carcinoma.
Topics: Animals; Aspirin; Blood Platelets; Carcinoma, Hepatocellular; CD8-Positive T-Lymphocytes; Cell Proliferation; Clopidogrel; Disease Models, Animal; Hepatitis B virus; Hepatitis B, Chronic; Humans; Liver Neoplasms; Mice; Platelet Aggregation Inhibitors; Ticlopidine | 2013 |
Oral anticoagulation and antiplatelets in atrial fibrillation patients after myocardial infarction and coronary intervention.
Topics: Administration, Oral; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Denmark; Drug Therapy, Combination; Female; Humans; Incidence; Male; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Complications; Registries; Risk Factors; Ticlopidine; Treatment Outcome | 2013 |
Comparative effect of clopidogrel and aspirin versus aspirin alone on laboratory parameters: a retrospective, observational, cohort study.
Topics: Aged; Aspirin; Biomarkers; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Hematologic Tests; Humans; Japan; Leukocytes; Linear Models; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Propensity Score; Retrospective Studies; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome | 2013 |
Antiplatelet drugs are a risk factor for esophageal mucosal injury.
Topics: Aged; Aged, 80 and over; Aryl Hydrocarbon Hydroxylases; Aspirin; Case-Control Studies; Clopidogrel; Cytochrome P-450 CYP2C19; Esophageal Perforation; Esophageal pH Monitoring; Gastroesophageal Reflux; Genotype; Humans; Middle Aged; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Ticlopidine | 2013 |
ACP Journal Club. Adding aspirin to clopidogrel worsened outcomes in PCI patients receiving oral anticoagulants.
Topics: Anticoagulants; Aspirin; Female; Humans; Male; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticlopidine | 2013 |
Animal models of gastric bleeding induced by dual antiplatelet therapy using aspirin and clopidogrel--prophylactic effect of antiulcer drugs.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Clopidogrel; Disease Models, Animal; Drug Synergism; Histamine H2 Antagonists; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Rats; Stomach Ulcer; Ticlopidine | 2014 |
Contact- and agonist-regulated microvesiculation of human platelets.
Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Cell Shape; Cell-Derived Microparticles; Clopidogrel; Fibrinogen; Humans; Microscopy, Atomic Force; Peptide Fragments; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2013 |
Carotid artery stenting outcomes: do they correlate with antiplatelet response assays?
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Brain Ischemia; Carotid Stenosis; Cerebral Revascularization; Clopidogrel; Drug Monitoring; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Platelet Aggregation Inhibitors; Prevalence; Receptors, Purinergic P2Y12; Registries; Retrospective Studies; Stents; Stroke; Ticlopidine; Treatment Outcome | 2014 |
Several platelet receptors and their ligands are involved in platelet- dependent thrombus formation.
Topics: Aspirin; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2013 |
Hidden implications: potential antiplatelet effects of adjuvant anaesthetic agents.
Topics: Adenosine Diphosphate; Adjuvants, Anesthesia; Aged; Aspirin; Cholecystectomy, Laparoscopic; Clopidogrel; Female; Hemorrhage; Humans; Intraoperative Complications; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombelastography; Ticlopidine | 2013 |
Risk of hemorrhagic complication associated with ventriculoperitoneal shunt placement in aneurysmal subarachnoid hemorrhage patients on dual antiplatelet therapy.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Female; Humans; Hydrocephalus; Intracranial Aneurysm; Intracranial Hemorrhages; Male; Middle Aged; Platelet Aggregation Inhibitors; Prosthesis Implantation; Risk; Subarachnoid Hemorrhage; Ticlopidine; Ventriculoperitoneal Shunt | 2013 |
Pharmacogenomics in cardiovascular disease: focus on aspirin and ADP receptor antagonists.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Humans; Pharmacogenetics; Purinergic P2Y Receptor Antagonists; Ticlopidine | 2013 |
Chasing the ACE of hearts.
Topics: Angiotensin-Converting Enzyme Inhibitors; Aspirin; Clopidogrel; Drug Therapy, Combination; Electrocardiography; Female; Heart Diseases; Heparin, Low-Molecular-Weight; Humans; Middle Aged; Sarcoidosis; Ticlopidine; Treatment Outcome | 2013 |
Early dual therapy for Chinese adults with TIA.
Topics: Aspirin; China; Clopidogrel; Drug Therapy, Combination; Female; Humans; Intracranial Hemorrhages; Ischemic Attack, Transient; Male; Platelet Aggregation Inhibitors; Secondary Prevention; Stroke; Ticlopidine | 2013 |
Impact of the proton pump inhibitors and CYP2C19*2 polymorphism on platelet response to clopidogrel as assessed by four platelet function assays.
Topics: Aged; Alleles; Aryl Hydrocarbon Hydroxylases; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug Resistance; Female; Humans; Male; Middle Aged; Platelet Function Tests; Polymorphism, Genetic; Proton Pump Inhibitors; Ticlopidine | 2013 |
Antiplatelet therapy and anticoagulants.
Topics: Anticoagulants; Aspirin; Female; Humans; Male; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticlopidine | 2013 |
Antiplatelet therapy and anticoagulants.
Topics: Anticoagulants; Aspirin; Female; Humans; Male; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticlopidine | 2013 |
Antiplatelet therapy and anticoagulants - authors' reply.
Topics: Anticoagulants; Aspirin; Female; Humans; Male; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticlopidine | 2013 |
Initial experiences with Multiplate® for rapid assessment of antiplatelet agent activity in neurosurgical emergencies.
Topics: Adenosine Diphosphate; Aged; Aged, 80 and over; Arachidonic Acid; Aspirin; Clopidogrel; Embolization, Therapeutic; Emergencies; Emergency Medical Services; Female; Hemostatic Techniques; Humans; Intracranial Hemorrhages; Male; Middle Aged; Neurosurgical Procedures; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Transfusion; Point-of-Care Systems; Ticlopidine | 2013 |
Multiple electrode aggregometry in antiplatelet-related intracerebral haemorrhage.
Topics: Adult; Aspirin; Blood Platelets; Brain Ischemia; Cerebral Hemorrhage; Clopidogrel; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2013 |
Pharmacogenomics of anti-platelet therapy focused on peripheral blood cells of coronary arterial disease patients.
Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Gene Expression; Gene Expression Profiling; Humans; Insulin-Like Growth Factor I; Leukocytes, Mononuclear; Male; Middle Aged; Multidrug Resistance-Associated Proteins; Oligonucleotide Array Sequence Analysis; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptor, IGF Type 1; Ticlopidine; Treatment Outcome | 2013 |
Toxicity studies of a bioactive protein with antithrombotic-thrombolytic activity, DLBS1033.
Topics: Analysis of Variance; Animals; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electrophoresis, Polyacrylamide Gel; Female; Fetal Development; Fibrinolytic Agents; Mice; No-Observed-Adverse-Effect Level; Oligochaeta; Pregnancy; Rats; Rats, Wistar; Ticlopidine; Tissue Extracts; Toxicity Tests, Acute | 2014 |
High-dose acetylsalicylic acid is superior to low-dose as well as to clopidogrel in preventing lipopolysaccharide-induced lung injury in mice.
Topics: Acute Lung Injury; Animals; Aspirin; Blood Platelets; Bronchoalveolar Lavage Fluid; Clopidogrel; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Neutrophil Infiltration; Ticlopidine | 2013 |
Gastrointestinal adverse events after dual antiplatelet therapy: clopidogrel is safer than ticagrelor, but prasugrel data are lacking or inconclusive.
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Chemical and Drug Induced Liver Injury; Clinical Trials, Phase III as Topic; Clopidogrel; Double-Blind Method; Female; Gastrointestinal Hemorrhage; Gastrointestinal Neoplasms; Humans; Kaplan-Meier Estimate; Male; Multicenter Studies as Topic; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Randomized Controlled Trials as Topic; Risk Factors; Thiophenes; Ticagrelor; Ticlopidine | 2013 |
Use and associated risks of concomitant aspirin therapy with oral anticoagulation in patients with atrial fibrillation: insights from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) Registry.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Cerebrovascular Disorders; Clopidogrel; Comorbidity; Dabigatran; Drug Synergism; Female; Fibrinolytic Agents; Follow-Up Studies; Hemorrhage; Hospitalization; Humans; Hypertrophy, Left Ventricular; Logistic Models; Male; Middle Aged; Models, Cardiovascular; Myocardial Ischemia; Platelet Aggregation Inhibitors; Prospective Studies; Registries; Risk; Ticlopidine; Treatment Outcome | 2013 |
The place of newer oral anticoagulants in the treatment of patients with non-valvular atrial fibrillation and coronary artery disease.
Topics: Administration, Oral; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Risk Factors; Stroke; Ticlopidine | 2013 |
The effect of antiplatelet and anticoagulant therapy on the clinical outcome of patients undergoing ureteroscopy.
Topics: Aged; Anticoagulants; Aspirin; Clopidogrel; Female; Humans; Lithotripsy, Laser; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Ticlopidine; Treatment Outcome; Ureteroscopy; Urolithiasis; Warfarin | 2013 |
Long-term effect of dual antiplatelet treatment after off-pump coronary artery bypass grafting.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Coronary Artery Bypass, Off-Pump; Drug Therapy, Combination; Endpoint Determination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Multivariate Analysis; Patient Readmission; Platelet Aggregation Inhibitors; Postoperative Complications; Prognosis; Retrospective Studies; Ticlopidine; Time Factors | 2013 |
Platelet reactivity in the early and late phases of acute coronary syndromes according to cytochrome P450 2C19 phenotypes.
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Alleles; Aryl Hydrocarbon Hydroxylases; Asian People; Aspirin; Clopidogrel; Cytochrome P-450 CYP2C19; Female; Humans; Male; Middle Aged; Phenotype; Platelet Activation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Receptors, Purinergic P2Y12; Stents; Ticlopidine | 2013 |
[The ARCTIC study].
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Drug-Eluting Stents; Heart Diseases; Humans; Myocardial Ischemia; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine | 2013 |
[The WOEST study].
Topics: Aspirin; Clopidogrel; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Randomized Controlled Trials as Topic; Ticlopidine | 2013 |
Prevalence of nonresponsiveness to aspirin in patients with symptomatic peripheral arterial disease using true point of care testing.
Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Female; Humans; Male; Peripheral Vascular Diseases; Platelet Aggregation; Platelet Aggregation Inhibitors; Point-of-Care Systems; Risk Factors; Ticlopidine | 2014 |
My patient had a small vessel stroke, are two antiplatelet agents better than one?
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stroke, Lacunar; Ticlopidine | 2013 |
Use of buddy wire to facilitate Y-configured stent placement in middle cerebral artery bifurcation aneurysms with daughter branches arising from the sac: a technical note.
Topics: Angiography, Digital Subtraction; Aspirin; Cerebral Angiography; Clopidogrel; Embolization, Therapeutic; Humans; Imaging, Three-Dimensional; Intracranial Aneurysm; Magnetic Resonance Imaging; Male; Middle Aged; Middle Cerebral Artery; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2014 |
Impact of the CYP2C19*17 polymorphism on the clinical outcome of clopidogrel therapy in Asian patients undergoing percutaneous coronary intervention.
Topics: Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Administration Schedule; Genetic Linkage; Genetic Variation; Genotype; Hemorrhage; Humans; Myocardial Infarction; Myocardial Ischemia; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Ticlopidine | 2013 |
Effects of endothelial dysfunction on residual platelet aggregability after dual antiplatelet therapy with aspirin and clopidogrel in patients with stable coronary artery disease.
Topics: Aged; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Endothelium, Vascular; Female; Humans; Linear Models; Logistic Models; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Purinergic P2Y12; Ticlopidine | 2013 |
[Not Available].
Topics: Aspirin; Female; Humans; Male; Platelet Aggregation Inhibitors; Stroke, Lacunar; Ticlopidine | 2013 |
Antiplatelet and anticoagulation therapy in microlaryngeal surgery.
Topics: Adult; Aged; Aspirin; Clopidogrel; Female; Fibrinolytic Agents; Follow-Up Studies; Humans; Incidence; Laryngeal Diseases; Laryngectomy; Laryngoplasty; Male; Microsurgery; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Preoperative Period; Retrospective Studies; Risk Factors; Thrombosis; Ticlopidine; Treatment Outcome; United States | 2014 |
Risks and benefits of early antithrombotic therapy after thrombolytic treatment in patients with acute stroke.
Topics: Administration, Oral; Aged; Aspirin; Brain; Clopidogrel; Female; Fibrinolytic Agents; Heparin; Humans; Injections, Intravenous; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Assessment; Secondary Prevention; Stroke; Thrombolytic Therapy; Ticlopidine | 2013 |
Acute myocardial infarction in pregnancy following unlicensed use of methylenedioxymethamphetamine ('Ecstasy').
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic Uptake Inhibitors; Adult; Aspirin; Bisoprolol; Chest Pain; Clopidogrel; Female; Humans; Infant, Newborn; Male; Myocardial Infarction; N-Methyl-3,4-methylenedioxyamphetamine; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Outcome; Ticlopidine | 2013 |
Defining predictive values using three different platelet function tests for CYP2C19 phenotype status on maintenance dual antiplatelet therapy after PCI.
Topics: Alleles; Aspirin; Blood Platelets; Clopidogrel; Cytochrome P-450 CYP2C19; Drug-Eluting Stents; Genotype; Humans; Myocardial Ischemia; Percutaneous Coronary Intervention; Phenotype; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; ROC Curve; Ticlopidine | 2014 |
Effect of antiplatelet therapy on thromboembolism after flow diversion with the pipeline embolization device.
Topics: Adolescent; Adult; Aged; Anticoagulants; Aspirin; Blood Vessel Prosthesis; Clopidogrel; Diffusion Magnetic Resonance Imaging; Embolization, Therapeutic; Female; Heparin; Humans; Intracranial Aneurysm; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Risk Factors; Stents; Thromboembolism; Ticlopidine; Treatment Outcome; Young Adult | 2013 |
PlaCor PRT measurement of shear-activated platelet aggregate formation in stable patients treated with single and dual antiplatelet therapy.
Topics: Aspirin; Blood Platelets; Blood Specimen Collection; Clopidogrel; Cohort Studies; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Risk Factors; Shear Strength; Ticlopidine | 2014 |
Efficacy and safety of aspirin, clopidogrel, and warfarin after coronary artery stenting in Korean patients with atrial fibrillation.
Topics: Aged; Anticoagulants; Asian People; Aspirin; Atrial Fibrillation; Blood Coagulation; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Disease-Free Survival; Drug Monitoring; Drug Therapy, Combination; Female; Hemorrhage; Humans; International Normalized Ratio; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Odds Ratio; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proportional Hazards Models; Republic of Korea; Retrospective Studies; Risk Factors; Stents; Stroke; Ticlopidine; Time Factors; Treatment Outcome; Warfarin | 2014 |
The postoperative bleeding rate and its risk factors in patients on antithrombotic therapy who undergo gastric endoscopic submucosal dissection.
Topics: Adenoma; Aged; Anti-Ulcer Agents; Anticoagulants; Aspirin; Carcinoma; Case-Control Studies; Clopidogrel; Dissection; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Gastroscopy; Humans; Logistic Models; Male; Middle Aged; Odds Ratio; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Proton Pump Inhibitors; Retrospective Studies; Risk Factors; Stomach Diseases; Stomach Neoplasms; Stomach Ulcer; Thienopyridines; Ticlopidine; Warfarin | 2013 |
Cost-effectiveness of different strategies for stroke prevention in patients with atrial fibrillation in a health resource-limited setting.
Topics: Anticoagulants; Aspirin; Atrial Fibrillation; China; Clopidogrel; Cost-Benefit Analysis; Drug Therapy, Combination; Humans; Models, Economic; Morpholines; Platelet Aggregation Inhibitors; Quality-Adjusted Life Years; Risk Factors; Rivaroxaban; Stroke; Thiophenes; Ticlopidine; Warfarin | 2014 |
Expert position paper on the role of platelet function testing in patients undergoing percutaneous coronary intervention.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Substitution; Drug Therapy, Combination; Genotype; Hemorrhage; Humans; Percutaneous Coronary Intervention; Platelet Activation; Platelet Function Tests; Practice Guidelines as Topic; Prognosis; Purinergic P2Y Receptor Antagonists; Thrombosis; Ticlopidine | 2014 |
Factors influencing multiplate whole blood impedance platelet aggregometry measurements, during aspirin treatment in acute ischemic stroke: a pilot study.
Topics: Adult; Aged; Aspirin; Blood Platelets; Brain Ischemia; C-Reactive Protein; Cholesterol, HDL; Clopidogrel; Electric Impedance; Female; Fibrinogen; Glycated Hemoglobin; Humans; Leukocyte Count; Leukocytes; Male; Middle Aged; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Stroke; Thromboxane B2; Ticlopidine; von Willebrand Factor | 2013 |
Predictors of 1-year outcomes in the Taiwan Acute Coronary Syndrome Full Spectrum Registry.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Patient Discharge; Platelet Aggregation Inhibitors; Prognosis; Registries; Stroke; Taiwan; Ticlopidine; Treatment Outcome | 2014 |
Endoscopic biopsy on patients taking antiplatelet agents: how much do we follow BSG, ASGE or ESGE guidelines?
Topics: Aspirin; Biopsy; Clopidogrel; Endoscopy, Gastrointestinal; Gastrointestinal Hemorrhage; Humans; Physicians; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Professional Practice; Risk; Surveys and Questionnaires; Ticlopidine | 2014 |
Novel uses for platelet function testing in the clinical laboratory: where are we now?
Topics: Aspirin; Blood Coagulation Tests; Clopidogrel; Drug Monitoring; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Randomized Controlled Trials as Topic; Risk; Ticlopidine | 2014 |
Cilostazol-based triple antiplatelet therapy in the era of generic clopidogrel and new potent antiplatelet agents.
Topics: Aspirin; Cilostazol; Clopidogrel; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Tetrazoles; Ticlopidine | 2014 |
Sex differences in spontaneous reports on adverse bleeding events of antithrombotic treatment.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aspirin; Child; Child, Preschool; Clopidogrel; Drug-Related Side Effects and Adverse Reactions; Female; Fibrinolytic Agents; Hemorrhage; Humans; Infant; Infant, Newborn; Male; Middle Aged; Practice Patterns, Physicians'; Risk; Sex Factors; Sweden; Ticlopidine; Warfarin; Young Adult | 2014 |
Risk factors of gastrointestinal bleeding in clopidogrel users: a nationwide population-based study.
Topics: Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Cohort Studies; Databases, Factual; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Proportional Hazards Models; Regression Analysis; Renal Insufficiency, Chronic; Risk Factors; Selective Serotonin Reuptake Inhibitors; Taiwan; Ticlopidine | 2013 |
[ASA and clopidogrel for urological operations. Perioperative management].
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Humans; Perioperative Care; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Ticlopidine; Urologic Surgical Procedures | 2013 |
[Primary angioplasty in a patient with acute inferior myocardial infarction: the unexpected trap].
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aortography; Aspirin; Cardiac Catheterization; Clopidogrel; Coronary Angiography; Coronary Vessel Anomalies; Electrocardiography; Female; Humans; Lysine; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Radial Artery; Stents; Ticlopidine; Tomography, X-Ray Computed | 2013 |
Duration of dual antiplatelet treatment with clopidogrel and aspirin in patients with acute coronary syndrome.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Hospitalization; Humans; Male; Platelet Aggregation Inhibitors; Prospective Studies; Recurrence; Risk Factors; Stents; Stroke; Ticlopidine; Treatment Outcome | 2014 |
Letter by Mangiacapra and Barbato regarding article, "Effects of endothelial dysfunction on residual platelet aggregability after dual antiplatelet therapy with aspirin and clopidogrel in patients with stable coronary artery disease".
Topics: Aspirin; Coronary Artery Disease; Endothelium, Vascular; Female; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2013 |
Response to letter regarding article, "Effects of endothelial dysfunction on residual platelet aggregability after dual antiplatelet therapy with aspirin and clopidogrel in patients with stable coronary artery disease".
Topics: Aspirin; Coronary Artery Disease; Endothelium, Vascular; Female; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2013 |
Effects of ex vivo platelet supplementation on platelet aggregability in blood samples from patients treated with acetylsalicylic acid, clopidogrel, or ticagrelor.
Topics: Adenosine; Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Peptide Fragments; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Transfusion; Ticagrelor; Ticlopidine | 2014 |
Efficacy of contemporary medical management for asymptomatic carotid artery stenosis.
Topics: Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Aspirin; Asymptomatic Diseases; Carotid Stenosis; Clopidogrel; Databases, Factual; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Proportional Hazards Models; Retrospective Studies; Stroke; Ticlopidine; Treatment Outcome; Warfarin | 2013 |
Antiplatelet resistance in outpatients with monitored adherence.
Topics: Aged; Aspirin; Clopidogrel; Cross-Sectional Studies; Drug Interactions; Drug Resistance; Female; Humans; Male; Medication Adherence; Outpatients; Platelet Aggregation Inhibitors; Surveys and Questionnaires; Ticlopidine | 2014 |
Changes in response to antiaggregatory treatment in patients with myeloproliferative neoplasms: a sequential study using multiple electrode aggregometry.
Topics: Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Aspirin; Blood Platelets; Case-Control Studies; Clopidogrel; Electrodes; Female; Hematologic Neoplasms; Humans; Male; Middle Aged; Myeloproliferative Disorders; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Thrombin; Thrombosis; Ticlopidine; Treatment Outcome | 2013 |
Antiplatelet therapy strategies after percutaneous coronary intervention in patients needing oral anticoagulation.
Topics: Anticoagulants; Aspirin; Female; Humans; Male; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticlopidine | 2013 |
Discontinuation of secondary prevention medication after myocardial infarction - the role of general practitioners and patients.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Clopidogrel; Female; General Practice; Guideline Adherence; Humans; Male; Medication Adherence; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Secondary Prevention; Surveys and Questionnaires; Ticlopidine | 2013 |
Impact of -455G/a polymorphism of the β-fibrinogen gene on platelet aggregation in patients with acute coronary syndrome.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Female; Fibrinogen; Genetic Predisposition to Disease; Genotype; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Risk Assessment; Ticlopidine | 2014 |
Monitoring persistent platelet reactivity in patients with unprotected left main stenting.
Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Prospective Studies; Stents; Ticlopidine | 2013 |
Predictors, cost, and outcomes of patients with acute coronary syndrome who receive optimal secondary prevention therapy: results from the antiplatelet treatment observational registries (APTOR).
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Clopidogrel; Europe; Female; Health Care Costs; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Predictive Value of Tests; Prospective Studies; Quality of Life; Registries; Secondary Prevention; Stents; Ticlopidine; Treatment Outcome | 2013 |
Platelet inhibition by adjunctive cilostazol suppresses the frequency of cerebral ischemic lesions after carotid artery stenting in patients with carotid artery stenosis.
Topics: Aged; Angioplasty; Aspirin; Brain Ischemia; Carotid Stenosis; Cilostazol; Clopidogrel; Diffusion Magnetic Resonance Imaging; Drug Resistance; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Stents; Tetrazoles; Ticlopidine; Time Factors; Treatment Outcome | 2014 |
[Use of clopidogrel with and without aspirin in patients receiving oral anticoagulant treatment and undergoing percutaneous coronary intervention: an open randomized and controlled trial].
Topics: Anticoagulants; Aspirin; Female; Humans; Male; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticlopidine | 2013 |
Antiplatelet therapy: DAPT for 3 months is sufficient.
Topics: Acute Coronary Syndrome; Aspirin; Coronary Artery Disease; Drug-Eluting Stents; Female; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine | 2014 |
Routine assessment of on-clopidogrel platelet reactivity and gene polymorphisms in predicting clinical outcome following drug-eluting stent implantation in patients with stable coronary artery disease.
Topics: Aged; Aryl Hydrocarbon Hydroxylases; Aspirin; Biotransformation; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Cytochrome P-450 CYP2C19; Decision Support Techniques; Drug Therapy, Combination; Drug-Eluting Stents; Female; Genotype; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Patient Selection; Percutaneous Coronary Intervention; Pharmacogenetics; Phenotype; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Genetic; Predictive Value of Tests; Proportional Hazards Models; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome | 2013 |
Platelet and leukocyte ROS production and lipoperoxidation are associated with high platelet reactivity in Non-ST elevation myocardial infarction (NSTEMI) patients on dual antiplatelet treatment.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Cell Separation; Clopidogrel; Drug Administration Schedule; Female; Flow Cytometry; Humans; Leukocytes; Lipid Peroxidation; Male; Middle Aged; Myocardial Infarction; Nephelometry and Turbidimetry; Platelet Aggregation; Platelet Aggregation Inhibitors; Reactive Oxygen Species; Ticlopidine | 2013 |
Ticlopidine and clopidogrel, sometimes combined with aspirin, only minimally increase the surgical risk in renal transplantation: a case-control study.
Topics: Aspirin; Blood Loss, Surgical; Case-Control Studies; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Graft Survival; Humans; Incidence; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Prognosis; Retrospective Studies; Risk; Risk Factors; Survival Rate; Ticlopidine; Time Factors | 2014 |
The enigmatic search for optimal DAPT duration.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Female; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine | 2014 |
Clopidogrel cessation triggers aspirin rebound in patients with coronary stent.
Topics: Aspirin; Clopidogrel; Drug Interactions; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Stents; Substance Withdrawal Syndrome; Ticlopidine | 2014 |
Sex differences in the treatment and outcome of patients with acute coronary syndrome after percutaneous coronary intervention: a population-based study.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Female; Humans; Insurance, Health; Male; Odds Ratio; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Population Surveillance; Propensity Score; Regression Analysis; Retrospective Studies; Sex Factors; Taiwan; Ticlopidine; Treatment Outcome | 2014 |
Spontaneous chest wall hematoma with dual antiplatelet therapy.
Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Follow-Up Studies; Hematoma; Humans; Male; Platelet Aggregation Inhibitors; Thoracic Wall; Ticlopidine; Tomography, X-Ray Computed | 2014 |
Thrombotic aortic restenosis after transapical SAPIEN valve implantation.
Topics: Aged, 80 and over; Anticoagulants; Aortic Valve Stenosis; Aspirin; Bioprosthesis; Clopidogrel; Echocardiography, Transesophageal; Heart Valve Prosthesis; Heart Valve Prosthesis Implantation; Heparin; Humans; Male; Prosthesis Failure; Recurrence; Thrombosis; Ticlopidine; Treatment Outcome | 2014 |
Thrombin-induced platelet-fibrin clot strength: relation to high on-clopidogrel platelet reactivity, genotype, and post-percutaneous coronary intervention outcomes.
Topics: Aged; Aspirin; Blood Coagulation; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 CYP2C19; Female; Fibrin; Genetic Testing; Genotype; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Polymorphism, Genetic; Predictive Value of Tests; Prognosis; Thrombelastography; Thrombin; Ticlopidine; Treatment Outcome | 2014 |
Haemodialysis impairs clopidogrel but not aspirin responsiveness in patients with end-stage renal disease. Results of a pilot study.
Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Follow-Up Studies; Humans; Kidney Failure, Chronic; Male; Middle Aged; Pilot Projects; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Receptors, Purinergic P2Y12; Renal Dialysis; Risk; Ticlopidine | 2014 |
Progressive hemorrhagic transformation following dual antiplatelet therapy.
Topics: Angiography, Digital Subtraction; Aspirin; Brain; Cerebral Angiography; Cerebral Hemorrhage; Clopidogrel; Constriction, Pathologic; Humans; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Male; Middle Aged; Neuroprotective Agents; Stents; Stroke; Thrombectomy; Ticlopidine; Tomography, X-Ray Computed | 2014 |
Impact of mild hypothermia on platelet responsiveness to aspirin and clopidogrel: an in vitro pharmacodynamic investigation.
Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Thrombosis; Drug Therapy, Combination; Female; Humans; Hypothermia, Induced; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Receptors, Purinergic P2Y12; Risk Factors; Ticlopidine; Treatment Outcome | 2014 |
Bleeding risk with triple antithrombotic therapy in patients with atrial fibrillation and drug-eluting stents.
Topics: Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Humans; Male; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Stroke; Thienopyridines; Ticlopidine; Warfarin | 2014 |
Antiplatelet drugs reduce the immunoinflammatory response in a rat model of periodontal disease.
Topics: Alveolar Bone Loss; Animals; Anti-Inflammatory Agents; Aspirin; Clopidogrel; Collagen; Connective Tissue; Disease Models, Animal; Gingiva; Inflammation Mediators; Male; Mandibular Diseases; Periodontitis; Peroxidase; Platelet Aggregation Inhibitors; Platelet Factor 4; Random Allocation; Rats; Rats, Sprague-Dawley; Ticlopidine | 2014 |
Neurovascular protection of cilostazol in stroke-prone spontaneous hypertensive rats associated with angiogenesis and pericyte proliferation.
Topics: Animals; Antigens; Aspirin; Cerebrovascular Circulation; Cilostazol; Clopidogrel; Disease Models, Animal; Endothelium; Fibrinolytic Agents; Male; Matrix Metalloproteinase 9; Neovascularization, Pathologic; Nerve Tissue Proteins; Pericytes; Proteoglycans; Rats; Rats, Inbred SHR; Stroke; Tetrazoles; Ticlopidine; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2014 |
Treating lacunar strokes occurring on aspirin: adding clopidogrel is not the simple solution.
Topics: Aspirin; Clopidogrel; Female; Humans; Male; Neuroprotective Agents; Platelet Aggregation Inhibitors; Stroke, Lacunar; Ticlopidine | 2014 |
Enteric-coated aspirin versus other antiplatelet drugs in acute non-cardioembolic ischemic stroke: post-marketing study in Japan.
Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Cerebral Infarction; Cilostazol; Dipyridamole; Female; Hemorrhage; Humans; Ischemic Attack, Transient; Japan; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Secondary Prevention; Stroke; Succinates; Tablets, Enteric-Coated; Tetrazoles; Ticlopidine | 2014 |
LOAD: a pilot study of the safety of loading of aspirin & clopidogrel in acute ischaemic stroke and transient ischaemic attack. Is the loading dose of aspirin and clopidogrel a good alternative for patients with acute ischaemic stroke and TIA? How this wi
Topics: Aspirin; Brain Ischemia; Female; Humans; Ischemic Attack, Transient; Male; Ticlopidine | 2013 |
Cigarette smoking and antiplatelet effects of aspirin monotherapy versus clopidogrel monotherapy in patients with atherosclerotic disease: results of a prospective pharmacodynamic study.
Topics: Adult; Aged; Aspirin; Atherosclerosis; Biomarkers; Blood Platelets; Clopidogrel; Cotinine; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Signal Transduction; Smoking; Thrombelastography; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2014 |
Response to antiplatelet therapy and platelet reactivity to thrombin receptor activating peptide-6 in cardiovascular interventions: Differences between peripheral and coronary angioplasty.
Topics: Adenosine Diphosphate; Aged; Angioplasty; Angioplasty, Balloon, Coronary; Arachidonic Acid; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Monocytes; P-Selectin; Peptide Fragments; Percutaneous Coronary Intervention; Peripheral Arterial Disease; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prognosis; Stents; Ticlopidine | 2014 |
Repeat head computed tomography in anticoagulated traumatic brain injury patients: still warranted.
Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Brain Injuries; Clopidogrel; Cohort Studies; Disease Progression; Female; Head Injuries, Closed; Humans; Intracranial Hemorrhages; Logistic Models; Male; Middle Aged; Multivariate Analysis; Registries; Retrospective Studies; Risk Factors; Ticlopidine; Tomography, X-Ray Computed; Warfarin | 2014 |
Increased risk for developing major adverse cardiovascular events in stented Chinese patients treated with dual antiplatelet therapy after concomitant use of the proton pump inhibitor.
Topics: Aged; Angioplasty, Balloon, Coronary; Asian People; Aspirin; Clopidogrel; Drug Combinations; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Retrospective Studies; Risk; Stents; Survival Analysis; Ticlopidine | 2014 |
The role of clinical parameters and of CYP2C19 G681 and CYP4F2 G1347A polymorphisms on platelet reactivity during dual antiplatelet therapy.
Topics: Adenosine Diphosphate; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Clopidogrel; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Epinephrine; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Thrombosis; Ticlopidine | 2014 |
Cost-effectiveness of optimal use of acute myocardial infarction treatments and impact on coronary heart disease mortality in China.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Aspirin; China; Clopidogrel; Computer Simulation; Coronary Disease; Cost-Benefit Analysis; Electrocardiography; Heparin; Hospital Mortality; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Markov Chains; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Ticlopidine | 2014 |
Reply to Rubino et al.
Topics: Aspirin; Coronary Artery Bypass; Female; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Postoperative Complications; Ticlopidine | 2014 |
A platelet P-selectin test predicts adverse cardiovascular events in patients with acute coronary syndromes treated with aspirin and clopidogrel.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Female; Humans; Male; P-Selectin; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine; Treatment Outcome | 2014 |
Clopidogrel enhances periodontal repair in rats through decreased inflammation.
Topics: Alveolar Bone Loss; Animals; Aspirin; Cell Count; Chemokine CCL5; Chemokine CXCL12; Clopidogrel; Infusions, Parenteral; Male; Microvessels; Neutrophil Infiltration; Neutrophils; Osteoclasts; Periodontal Attachment Loss; Periodontitis; Periodontium; Platelet Aggregation Inhibitors; Platelet Factor 4; Platelet-Derived Growth Factor; Random Allocation; Rats; Rats, Sprague-Dawley; Sodium Chloride; Ticlopidine | 2014 |
Variation in thromboxane B2 concentrations in serum and plasma in patients taking regular aspirin before and after clopidogrel therapy.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Cross-Sectional Studies; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Thromboxane B2; Ticlopidine; Treatment Outcome | 2015 |
Association of thrombin generation potential with platelet PAR-1 regulation and P-selectin expression in patients on dual antiplatelet therapy.
Topics: Adult; Aged; Aspirin; Biomarkers; Blood Platelets; Case-Control Studies; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; P-Selectin; Peptide Fragments; Piperazines; Platelet Activation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Prothrombin; Receptor, PAR-1; Thiophenes; Thrombin; Ticlopidine | 2014 |
Fixed-dose aspirin-clopidogrel combination enhances compliance to aspirin after acute coronary syndrome.
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Coronary Thrombosis; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Male; Medication Adherence; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine | 2014 |
Role of paraoxonase-1 in CYP2C19 loss-of-function carriers.
Topics: Aryl Hydrocarbon Hydroxylases; Aryldialkylphosphatase; Aspirin; Female; Humans; Male; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine | 2014 |
Adenosine diphosphate-induced single-platelet count aggregation and bleeding in clopidogrel-treated patients undergoing coronary artery bypass grafting.
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Aged; Anesthesia; Aspirin; Blood Transfusion; Chest Tubes; Clopidogrel; Confidence Intervals; Coronary Artery Bypass; Critical Care; Erythrocyte Count; Female; Humans; Linear Models; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Postoperative Hemorrhage; Prospective Studies; Risk Factors; Ticlopidine | 2014 |
Immune thrombocytopenic purpura and myocardial infarction: a dilemma of management.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Disease Management; Female; Glucocorticoids; Humans; Immunoglobulins, Intravenous; Mechanical Thrombolysis; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Purpura, Thrombocytopenic, Idiopathic; Stents; Ticlopidine; Treatment Outcome | 2013 |
Analysis of gastrointestinal prophylaxis in patients receiving dual antiplatelet therapy with aspirin and clopidogrel.
Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Guideline Adherence; Hospitalization; Humans; Male; Middle Aged; Patient Readmission; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Proton Pump Inhibitors; Retrospective Studies; Risk Factors; Ticlopidine; Treatment Outcome | 2014 |
[Rescue treatment in acute thrombosis of intracranial stents].
Topics: Abciximab; Antibodies, Monoclonal; Aspirin; Basilar Artery; Capillary Permeability; Cerebral Angiography; Clopidogrel; Equipment Design; Female; Fibrinolytic Agents; Hemorheology; Humans; Immunoglobulin Fab Fragments; Intracranial Aneurysm; Intracranial Thrombosis; Middle Aged; Platelet Aggregation Inhibitors; Recurrence; Salvage Therapy; Stents; Thrombolytic Therapy; Ticlopidine | 2014 |
Secondary prevention of atherothrombotic or cryptogenic stroke.
Topics: Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Clopidogrel; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Life Style; Platelet Aggregation Inhibitors; Pyrroles; Recurrence; Risk Factors; Secondary Prevention; Stroke; Ticlopidine | 2014 |
Antiplatelet therapy for stable coronary artery disease in atrial fibrillation patients taking an oral anticoagulant: a nationwide cohort study.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Cohort Studies; Comorbidity; Coronary Artery Disease; Drug Therapy, Combination; Female; Hemorrhage; Humans; Incidence; Male; Middle Aged; Myocardial Infarction; Phenprocoumon; Platelet Aggregation Inhibitors; Risk Factors; Stroke; Ticlopidine; Vitamin K; Warfarin | 2014 |
[Real-world study in analysis of effects on concomitant medications with parenterally administered shenmai for coronary heart disease].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Coronary Disease; Drug Combinations; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Hospital Information Systems; Humans; Infusions, Parenteral; Logistic Models; Male; Middle Aged; Outcome Assessment, Health Care; Pragmatic Clinical Trials as Topic; Ticlopidine; Treatment Outcome; Young Adult | 2013 |
Smoking status and the effects of antiplatelet drugs.
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Clopidogrel; Female; Humans; Male; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Smoking; Thiophenes; Ticagrelor; Ticlopidine; Treatment Outcome | 2013 |
Warfarin: Impact on hemostasis after radial catheterization.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Cardiac Catheterization; Catheterization, Peripheral; Clopidogrel; Databases, Factual; Drug Administration Schedule; Female; Hemorrhage; Hemostasis; Hemostatic Techniques; Humans; Logistic Models; Male; Middle Aged; Odds Ratio; Platelet Aggregation Inhibitors; Radial Artery; Retrospective Studies; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome; Warfarin | 2015 |
Spontaneous omental bleeding in the setting of dual anti-platelet therapy with ticagrelor.
Topics: Adenosine; Aged; Aspirin; Clopidogrel; Gastrointestinal Hemorrhage; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Ticagrelor; Ticlopidine | 2014 |
Switching from aspirin to clopidogrel in patients with aspirin resistance after an ischemic stroke. Is it a good solution?
Topics: Aged; Aged, 80 and over; Aspirin; Brain Ischemia; Clopidogrel; Drug Resistance; Drug Substitution; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Secondary Prevention; Stroke; Ticlopidine | 2014 |
Dual antiplatelet therapy (clopidogrel and aspirin) is associated with increased all-cause mortality after carotid revascularization for asymptomatic carotid disease.
Topics: Aged; Alabama; Angioplasty; Aspirin; Asymptomatic Diseases; Carotid Stenosis; Clopidogrel; Drug Therapy, Combination; Endarterectomy, Carotid; Female; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Patient Discharge; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Stents; Stroke; Ticlopidine; Time Factors; Treatment Outcome | 2014 |
Transcatheter closure of ruptured sinus of Valsalva aneurysm into the right ventricle with an Amplatzer Vascular Plug II.
Topics: Aortic Rupture; Aortography; Aspirin; Cardiac Catheterization; Clopidogrel; Drug Therapy, Combination; Echocardiography, Transesophageal; Equipment Design; Female; Hemodynamics; Humans; Middle Aged; Platelet Aggregation Inhibitors; Sinus of Valsalva; Ticlopidine; Treatment Outcome | 2015 |
Positive clinical response to clopidogrel is independent of paraoxonase 1 Q192R and CYP2C19 genetic variants.
Topics: Aged; Alleles; Angina Pectoris; Aryldialkylphosphatase; Aspirin; Clopidogrel; Cohort Studies; Coronary Disease; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C19 Inhibitors; Drug Therapy, Combination; Female; Genetic Variation; Genotype; Hospitalization; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Recurrence; Risk Factors; Ticlopidine; Treatment Outcome | 2014 |
Initial experience with ticagrelor in patients with critical limb ischemia and high on-clopidogrel platelet reactivity undergoing complex peripheral endovascular procedures.
Topics: Adenosine; Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Endovascular Procedures; Female; Follow-Up Studies; Humans; Leg; Limb Salvage; Male; Middle Aged; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Platelet Function Tests; Purinergic P2Y Receptor Antagonists; Retrospective Studies; Survival Rate; Ticagrelor; Ticlopidine; Treatment Outcome | 2014 |
Factor XIII Val34Leu polymorphism and recurrent myocardial infarction in patients with coronary artery disease.
Topics: Adult; Aged; Amino Acid Substitution; Aspirin; Clopidogrel; Coronary Artery Disease; Factor XIII; Female; Fibrin; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Thrombelastography; Ticlopidine | 2014 |
Impact of preoperative antiplatelet therapy on in-hospital outcomes after coronary artery bypass grafting.
Topics: Aspirin; Coronary Artery Bypass; Female; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Postoperative Complications; Ticlopidine | 2014 |
Hybrid strategy for unstable patients with severe carotid and cardiac disease requiring surgery.
Topics: Aged; Angioplasty, Balloon; Anticoagulants; Aspirin; Cardiac Surgical Procedures; Carotid Artery Diseases; Clopidogrel; Female; Heart Diseases; Hemodynamics; Heparin; Hospital Mortality; Hospitals, High-Volume; Hospitals, University; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Severity of Illness Index; Stents; Ticlopidine; Time Factors; Treatment Outcome | 2015 |
Duration of dual antiplatelet therapy following percutaneous coronary intervention on re-hospitalization for acute coronary syndrome.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Chi-Square Distribution; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Multivariate Analysis; Patient Readmission; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proportional Hazards Models; Retrospective Studies; Risk Factors; Taiwan; Ticlopidine; Time Factors; Treatment Outcome | 2014 |
Prospective registry of carotid artery stenting in Japan--investigation on device and antiplatelet for carotid artery stenting.
Topics: Aged; Aged, 80 and over; Aspirin; Carotid Arteries; Carotid Stenosis; Cilostazol; Clopidogrel; Drug Therapy, Combination; Endarterectomy, Carotid; Female; Humans; Japan; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Registries; Stents; Tetrazoles; Ticlopidine; Treatment Outcome | 2014 |
The effects of CES1A2 A(-816)C and CYP2C19 loss-of-function polymorphisms on clopidogrel response variability among Chinese patients with coronary heart disease.
Topics: Aged; Aryldialkylphosphatase; Aspirin; ATP Binding Cassette Transporter, Subfamily D, Member 1; ATP-Binding Cassette Transporters; Carboxylic Ester Hydrolases; Case-Control Studies; China; Clopidogrel; Coronary Disease; Cytochrome P-450 CYP2C19; Female; Genetic Variation; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Prospective Studies; Risk Factors; Stents; Ticlopidine | 2014 |
Treatment of blister-like aneurysms with the pipeline embolization device.
Topics: Adult; Aged; Aged, 80 and over; Aneurysm, Ruptured; Angioplasty; Aspirin; Basilar Artery; Carotid Artery Diseases; Carotid Artery, Internal; Cerebral Angiography; Clopidogrel; Drug Therapy, Combination; Embolization, Therapeutic; Female; Follow-Up Studies; Heparin; Humans; Intracranial Aneurysm; Magnetic Resonance Angiography; Male; Middle Aged; Platelet Aggregation Inhibitors; Premedication; Retrospective Studies; Stents; Ticlopidine; Tomography, X-Ray Computed; Treatment Outcome | 2014 |
Intracranial stenosis: impact of randomized trials on treatment preferences of US neurologists and neurointerventionists.
Topics: Angioplasty; Aspirin; Cerebral Arteries; Clopidogrel; Constriction, Pathologic; Drug Therapy, Combination; Drug Utilization; Fibrinolytic Agents; Health Care Surveys; Humans; Intracranial Arteriosclerosis; Neurology; Practice Patterns, Physicians'; Radiology, Interventional; Randomized Controlled Trials as Topic; Risk Reduction Behavior; Secondary Prevention; Stents; Stroke; Surveys and Questionnaires; Ticlopidine; United States; Warfarin | 2014 |
Clopidogrel resistance in diabetic patient with acute myocardial infarction due to stent thrombosis.
Topics: Aged, 80 and over; Aspirin; Clopidogrel; Coronary Angiography; Diabetes Mellitus, Type 2; Drug Resistance; Electrocardiography; Heparin; Humans; Myocardial Infarction; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Stents; Thiophenes; Thrombosis; Ticlopidine | 2014 |
Tips for GP trainees working in vascular surgery.
Topics: Anticholesteremic Agents; Aspirin; Blood Pressure; Clinical Competence; Clopidogrel; Education, Medical, Graduate; General Practice; Humans; Learning; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Simvastatin; Smoking Cessation; Ticlopidine; Vascular Diseases; Vascular Surgical Procedures | 2014 |
Prevalence of CYP2C19 variant alleles and pharmacodynamic variability of aspirin and clopidogrel in Native Americans.
Topics: Aged; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Gene Frequency; Humans; Indians, North American; Male; Middle Aged; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Ticlopidine | 2014 |
Differences in thrombus structure and kinetics in patients with type 2 diabetes mellitus after non ST elevation acute coronary syndrome.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine | 2014 |
HeartWare left ventricular assist device thrombosis in aspirin non-responder.
Topics: Aged; Aspirin; Cardiomyopathy, Dilated; Clopidogrel; Drug Resistance; Drug Substitution; Fibrinolytic Agents; Heart Valve Prosthesis; Humans; International Normalized Ratio; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Prosthesis Design; Thrombolytic Therapy; Thrombosis; Ticlopidine; Treatment Outcome; Ventricular Function, Left | 2014 |
Association between the microarray-based CYP2C19 genotyping assay and the platelet function test in cardiovascular patients receiving clopidogrel.
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Alleles; Asian People; Aspirin; Blood Platelets; Clopidogrel; Cytochrome P-450 CYP2C19; Gene Expression; Genotype; Humans; Isoenzymes; Microarray Analysis; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Receptors, Purinergic P2Y12; Ticlopidine | 2014 |
Effectiveness and safety of antiplatelet in stroke patients with end-stage renal disease undergoing dialysis.
Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Kidney Failure, Chronic; Male; Middle Aged; Platelet Aggregation Inhibitors; Recurrence; Renal Dialysis; Retrospective Studies; Stroke; Ticlopidine; Treatment Outcome | 2014 |
Safer heart-attack prevention for seniors with revised drug regimen. Half the normal dose of prasugrel, a lifesaving medication, is just as effective as the larger dose, and reduces risk of serious side effects.
Topics: Aged; Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Middle Aged; Myocardial Infarction; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Randomized Controlled Trials as Topic; Secondary Prevention; Thiophenes; Ticlopidine | 2013 |
Point-of-care testing of clopidogrel-mediated platelet inhibition and risk for cardiovascular events after coronary angiography with or without percutaneous coronary intervention.
Topics: Adenosine Diphosphate; Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Angiography; Female; Humans; Male; Middle Aged; Myocardial Infarction; Patient Readmission; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Point-of-Care Systems; Predictive Value of Tests; Prospective Studies; ROC Curve; Stents; Survival Analysis; Thrombosis; Ticlopidine | 2014 |
Dual antiplatelet therapy over 6 months increases the risk of bleeding after biodegradable polymer-coated sirolimus eluting stents implantation: insights from the CREATE study.
Topics: Aspirin; Biodegradable Plastics; Clopidogrel; Drug-Eluting Stents; Female; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine | 2014 |
Efficacy and safety of antiplatelet-combination therapy after drug-eluting stent implantation.
Topics: Aged; Antiplatyhelmintic Agents; Aspirin; Clopidogrel; Drug Combinations; Drug Resistance; Drug-Eluting Stents; Female; Humans; Intention to Treat Analysis; Male; Middle Aged; Myocardial Ischemia; Percutaneous Coronary Intervention; Platelet Function Tests; Prospective Studies; Tablets; Ticlopidine; Time Factors; Treatment Outcome | 2014 |
Aspirin improves outcome in high risk prostate cancer patients treated with radiation therapy.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Chemoradiotherapy; Clopidogrel; Drug Screening Assays, Antitumor; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Metastasis; Prostatic Neoplasms; Retrospective Studies; Risk; Ticlopidine; Treatment Outcome; Warfarin | 2014 |
Triple versus dual antiplatelet therapy after percutaneous coronary intervention for coronary bifurcation lesions: results from the COBIS (COronary BIfurcation Stent) II Registry.
Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Logistic Models; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Republic of Korea; Retrospective Studies; Stroke; Tetrazoles; Ticlopidine; Treatment Outcome | 2015 |
Comparative study of three modified numerical spectrophotometric methods: an application on pharmaceutical ternary mixture of aspirin, atorvastatin and clopedogrel.
Topics: Aspirin; Atorvastatin; Clopidogrel; Heptanoic Acids; Pyrroles; Spectrophotometry; Ticlopidine | 2014 |
Prognostic value of bleeding after percutaneous coronary intervention in patients with diabetes.
Topics: Abciximab; Aged; Antibodies, Monoclonal; Anticoagulants; Antithrombins; Aspirin; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus, Type 2; Female; Hemorrhage; Heparin; Hirudins; Humans; Immunoglobulin Fab Fragments; Logistic Models; Male; Middle Aged; Peptide Fragments; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prognosis; Proportional Hazards Models; Recombinant Proteins; Risk Factors; Stents; Ticlopidine | 2014 |
Aortic arch atheroma: a plaque of a different color or more of the same?
Topics: Anticoagulants; Aortic Diseases; Aspirin; Clopidogrel; Female; Humans; Male; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Warfarin | 2014 |
A cautionary tale on the use of antiplatelet treatment following TURP.
Topics: Aged; Aspirin; Clopidogrel; Coronary Thrombosis; Drug-Eluting Stents; Hematuria; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Postoperative Complications; Thrombosis; Ticlopidine; Transurethral Resection of Prostate; Urinary Bladder; Urinary Bladder Diseases | 2014 |
Does rebamipide prevent gastric mucosal injury in patients taking aspirin and clopidogrel?
Topics: Alanine; Anti-Ulcer Agents; Aspirin; Clopidogrel; Gastrointestinal Hemorrhage; Humans; Male; Platelet Aggregation Inhibitors; Quinolones; Ticlopidine | 2014 |
Dual antiplatelet therapy after stent implantation.
Topics: Acute Coronary Syndrome; Aspirin; Coronary Artery Disease; Drug-Eluting Stents; Female; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine | 2014 |
Dual antiplatelet therapy after stent implantation--reply.
Topics: Acute Coronary Syndrome; Aspirin; Coronary Artery Disease; Drug-Eluting Stents; Female; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine | 2014 |
[Comparative assessment of antiaggregant efficacy of acetylsalicylic acid and clopidogrel in peripheral atherosclerosis].
Topics: Aged; Aspirin; Clopidogrel; Female; Humans; Lower Extremity; Male; Middle Aged; Patient Selection; Peripheral Arterial Disease; Platelet Aggregation; Platelet Aggregation Inhibitors; Severity of Illness Index; Therapeutic Equivalency; Ticlopidine; Treatment Outcome | 2014 |
Use of thromboelastography to tailor dual-antiplatelet therapy in patients undergoing treatment of intracranial aneurysms with the Pipeline embolization device.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Vessel Prosthesis; Clopidogrel; Drug Therapy, Combination; Embolization, Therapeutic; Female; Follow-Up Studies; Humans; Intracranial Aneurysm; Male; Middle Aged; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Thrombelastography; Ticlopidine; Treatment Outcome | 2015 |
Thrombocytosis is associated with increased short and long term mortality after exacerbation of chronic obstructive pulmonary disease: a role for antiplatelet therapy?
Topics: Aged; Aspirin; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Pulmonary Disease, Chronic Obstructive; Spirometry; Thrombocytosis; Ticlopidine | 2014 |
The devastating power of platelets in COPD exacerbations: can aspirin save lives in COPD?
Topics: Aspirin; Clopidogrel; Female; Humans; Male; Platelet Aggregation Inhibitors; Pulmonary Disease, Chronic Obstructive; Thrombocytosis; Ticlopidine | 2014 |
Expert position paper on the management of antiplatelet therapy in patients undergoing coronary artery bypass graft surgery.
Topics: Adenosine; Aspirin; Blood Platelets; Clopidogrel; Consensus; Coronary Artery Bypass; Drug Therapy, Combination; Humans; Piperazines; Platelet Aggregation Inhibitors; Postoperative Care; Prasugrel Hydrochloride; Preoperative Care; Purinergic P2Y Receptor Antagonists; Risk Assessment; Risk Factors; Thiophenes; Ticagrelor; Ticlopidine | 2014 |
Subacute bioresorbable vascular scaffold thrombosis: a report of 2 cases.
Topics: Absorbable Implants; Adenosine; Aged; Aspirin; Clopidogrel; Coronary Angiography; Coronary Stenosis; Coronary Thrombosis; Coronary Vessels; Drug-Eluting Stents; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Ticagrelor; Ticlopidine; Treatment Outcome | 2015 |
Successful multidisciplinary treatment of hilar cholangiocarcinoma in a patient with complicated new-onset coronary artery disease.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Chemotherapy, Adjuvant; Cholangiocarcinoma; Clopidogrel; Combined Modality Therapy; Coronary Artery Disease; Hepatectomy; Humans; Jejunostomy; Male; Neoadjuvant Therapy; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2014 |
[Hematemesis in an 80-year-old patient with chest pain and nausea].
Topics: Aged, 80 and over; Aspirin; Chest Pain; Clopidogrel; Esophageal Diseases; Esophagoscopy; Female; Hematemesis; Hematoma; Humans; Nausea; Platelet Aggregation Inhibitors; Rupture, Spontaneous; Ticlopidine; Tomography, X-Ray Computed | 2015 |
SUPERA interwoven nitinol Stent Outcomes in Above-Knee IntErventions (SAKE) study.
Topics: Aged; Aged, 80 and over; Alloys; Ankle Brachial Index; Aspirin; Clopidogrel; Constriction, Pathologic; Drug Therapy, Combination; Endovascular Procedures; Female; Femoral Artery; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Popliteal Artery; Predictive Value of Tests; Prosthesis Design; Radiography; Retrospective Studies; Severity of Illness Index; Stents; Ticlopidine; Time Factors; Treatment Outcome; Vascular Patency | 2014 |
Triple antithrombotic therapy: risky but sometimes necessary.
Topics: Anticoagulants; Aspirin; Benzimidazoles; beta-Alanine; Clinical Trials as Topic; Clopidogrel; Dabigatran; Drug Therapy, Combination; Humans; Morpholines; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Pyrazoles; Pyridones; Rivaroxaban; Thiophenes; Ticlopidine; Vitamin K | 2014 |
Stent placement for complex middle cerebral artery aneurysms.
Topics: Adult; Aged; Aneurysm, Ruptured; Anticoagulants; Aspirin; Cerebral Angiography; Clopidogrel; Female; Humans; Intracranial Aneurysm; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Stents; Ticlopidine; Treatment Failure; Treatment Outcome | 2014 |
Successful treatment of bleeding large duodenal gastrointestinal stromal tumour in a patient under dual antiplatelet therapy after recent drug-eluting coronary stent implantation.
Topics: Aged; Aspirin; Benzamides; Chemotherapy, Adjuvant; Clopidogrel; Coronary Stenosis; Drug-Eluting Stents; Duodenal Neoplasms; Gastrointestinal Hemorrhage; Gastrointestinal Stromal Tumors; Hemostatic Techniques; Humans; Imatinib Mesylate; Male; Neoadjuvant Therapy; Piperazines; Platelet Aggregation Inhibitors; Pyrimidines; Ticlopidine | 2014 |
Longitudinal assessment of von Willebrand factor antigen and von Willebrand factor propeptide in response to alteration of antiplatelet therapy after TIA or ischaemic stroke.
Topics: Adult; Aged; Aspirin; Clopidogrel; Dipyridamole; Enzyme-Linked Immunosorbent Assay; Female; Humans; Ischemic Attack, Transient; Longitudinal Studies; Male; Middle Aged; Pilot Projects; Platelet Aggregation Inhibitors; Protein Precursors; Statistics, Nonparametric; Stroke; Ticlopidine; Time Factors; von Willebrand Factor | 2014 |
[A new technology for evaluating pharmacodynamics of antiaggregants].
Topics: Adult; Aspirin; Blood Coagulation; Clopidogrel; Cyclooxygenase 1; Fibrinogen; Healthy Volunteers; Humans; Kinetics; Male; Pentoxifylline; Platelet Aggregation Inhibitors; Precision Medicine; Receptors, Purinergic P2; Thrombelastography; Thrombin; Ticlopidine | 2014 |
Thrombotic and bleeding events after coronary stenting according to clopidogrel and aspirin platelet reactivity: VerifyNow French Registry (VERIFRENCHY).
Topics: Aged; Aspirin; Clopidogrel; Coronary Thrombosis; Drug Therapy, Combination; Female; France; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prospective Studies; Registries; Risk Factors; Stents; Ticlopidine; Treatment Outcome | 2014 |
Fixed combination dual antiplatelet therapy and the risk of stent thrombosis.
Topics: Aged, 80 and over; Aspirin; Clopidogrel; Coronary Thrombosis; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Medication Adherence; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine | 2014 |
Pharmacologic strategy for one repeated stent thrombosis patient with hyporesponsiveness to standard dual antiplatelet therapy.
Topics: Aspirin; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Electrocardiography; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Recurrence; Smoking; Stents; Thrombosis; Ticlopidine | 2015 |
Acute coronary thrombosis and multiple coronary aneurysms in a 22-year-old man with the human immunodeficiency virus.
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coronary Aneurysm; Coronary Angiography; Coronary Thrombosis; Electrocardiography; HIV; HIV Infections; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Treatment Outcome; Young Adult | 2014 |
Perioperative management of antiplatelet therapy in patients with coronary stents undergoing cardiac and non-cardiac surgery: a consensus document from Italian cardiological, surgical and anaesthesiological societies.
Topics: Anesthesiology; Aspirin; Cardiac Surgical Procedures; Cardiology; Clopidogrel; Eptifibatide; Hemorrhage; Humans; Italy; Myocardial Ischemia; Peptides; Perioperative Care; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Risk Assessment; Societies, Medical; Stents; Surgical Procedures, Operative; Thoracic Surgery; Ticlopidine; Tirofiban; Tyrosine | 2014 |
Multi-parameter assessment of platelet inhibition and its stability during aspirin and clopidogrel therapy.
Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine | 2014 |
Posttreatment platelet reactivity on clopidogrel is associated with the risk of adverse events after off-pump coronary artery bypass.
Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Cohort Studies; Coronary Artery Bypass, Off-Pump; Coronary Artery Disease; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Revascularization; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; ROC Curve; Ticlopidine | 2014 |
The quality of antiplatelet and anticoagulant medication administration among ST-segment elevation myocardial infarction patients transferred for primary percutaneous coronary intervention.
Topics: Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Cohort Studies; Early Medical Intervention; Female; Guideline Adherence; Heparin; Heparin, Low-Molecular-Weight; Hirudins; Humans; Male; Middle Aged; Myocardial Infarction; Patient Transfer; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Practice Guidelines as Topic; Pyridines; Recombinant Proteins; Retrospective Studies; Ticlopidine; Time-to-Treatment | 2014 |
[Adding clopidogrel after stroke while on aspirin-does not help, only hurts].
Topics: Aspirin; Female; Humans; Male; Neuroprotective Agents; Platelet Aggregation Inhibitors; Stroke, Lacunar; Ticlopidine | 2014 |
Gender differences in hemorheological parameters and in in vitro platelet aggregation in acetylsalicylic acid and clopidogrel treated vascular patients.
Topics: Aged; Aspirin; Clopidogrel; Erythrocyte Aggregation; Female; Fibrinogen; Hematocrit; Humans; In Vitro Techniques; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Rheology; Ticlopidine | 2014 |
Adverse cardiovascular outcomes in relation to suboptimal antithrombotic therapy use in patients undergoing peripheral artery disease angioplasty: lost opportunities?
Topics: Aged; Aged, 80 and over; Angioplasty; Anticoagulants; Aspirin; Clopidogrel; Cohort Studies; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Peripheral Arterial Disease; Retrospective Studies; Ticlopidine; Treatment Outcome | 2015 |
Impact of the adjusted dosing regimen of prasugrel for Japanese patients with acute coronary syndrome undergoing percutaneous coronary intervention.
Topics: Aspirin; Humans; Piperazines; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Thiophenes; Ticlopidine | 2014 |
Cost-effectiveness of clopidogrel-aspirin versus aspirin alone for acute transient ischemic attack and minor stroke.
Topics: Aspirin; China; Clopidogrel; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combination; Female; Humans; Ischemic Attack, Transient; Male; Markov Chains; Middle Aged; Outcome Assessment, Health Care; Platelet Aggregation Inhibitors; Quality-Adjusted Life Years; Stroke; Ticlopidine | 2014 |
Proton-pump inhibitors in patients requiring antiplatelet therapy: new FDA labeling.
Topics: Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Antagonism; Drug Labeling; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Risk Factors; Ticlopidine; United States; United States Food and Drug Administration | 2014 |
Delayed ischemic stroke after stent-assisted coil placement in cerebral aneurysm: characteristics and optimal duration of preventative dual antiplatelet therapy.
Topics: Aspirin; Clopidogrel; Embolization, Therapeutic; Female; Humans; Intracranial Aneurysm; Male; Middle Aged; Platelet Aggregation Inhibitors; Registries; Retrospective Studies; Stents; Stroke; Ticlopidine; Treatment Outcome | 2014 |
Cholesterol embolization syndrome with an atypical proximal presentation simulating calciphylaxis.
Topics: Aspirin; Back; Buttocks; Calciphylaxis; Cardiac Catheterization; Clopidogrel; Diagnosis, Differential; Embolism, Cholesterol; Erythema; Female; Humans; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Skin Ulcer; Thigh; Ticlopidine | 2014 |
[Urolithiasis - settle antiplatelets before ureteroscopy?].
Topics: Anticoagulants; Aspirin; Female; Humans; Lithotripsy, Laser; Male; Platelet Aggregation Inhibitors; Ticlopidine; Ureteroscopy; Urolithiasis; Warfarin | 2014 |
Risk and benefit of dual antiplatelet treatment among non-revascularized myocardial infarction patients in different age groups.
Topics: Age Distribution; Age Factors; Aged; Aspirin; Cause of Death; Clopidogrel; Denmark; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Incidence; Male; Middle Aged; Myocardial Infarction; Myocardial Revascularization; Platelet Aggregation Inhibitors; Propensity Score; Registries; Retrospective Studies; Survival Rate; Ticlopidine; Time Factors; Treatment Outcome | 2017 |
ST-segment elevation myocardial infarction in China from 2001 to 2011 (the China PEACE-Retrospective Acute Myocardial Infarction Study): a retrospective analysis of hospital data.
Topics: Aged; Aspirin; China; Clopidogrel; Female; Fibrinolytic Agents; Healthcare Disparities; Hospital Mortality; Hospitals, Rural; Hospitals, Urban; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Reperfusion; Patient Admission; Percutaneous Coronary Intervention; Quality of Health Care; Retrospective Studies; Ticlopidine; Treatment Outcome | 2015 |
[Perioperative management and postoperative complication rates of patients on dual antiplatelet therapies after coronary drug eluting stent implantation].
Topics: Aged; Aged, 80 and over; Aspirin; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Perioperative Care; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Surgical Procedures, Operative; Thrombosis; Ticlopidine; Time Factors | 2014 |
Comparative effects of the anti-platelet drugs, clopidogrel, ticlopidine, and cilostazol on aspirin-induced gastric bleeding and damage in rats.
Topics: Animals; Aspirin; Cilostazol; Clopidogrel; Hemoglobins; Hemorrhage; Male; Peroxidase; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Stomach Diseases; Tetrazoles; Ticlopidine | 2014 |
Prevalence of deep vein thrombosis in acutely admitted ambulatory non-surgical intensive care unit patients.
Topics: Aged; Aged, 80 and over; Anticoagulants; APACHE; Aspirin; Clopidogrel; Female; Fibrin Fibrinogen Degradation Products; Germany; Heparin; Humans; Intensive Care Units; Male; Middle Aged; Outpatient Clinics, Hospital; Patient Admission; Platelet Aggregation Inhibitors; Prevalence; Prospective Studies; Pulmonary Embolism; Risk Factors; Ticlopidine; Venous Thromboembolism; Venous Thrombosis | 2014 |
Spontaneous resolution of nontraumatic chronic subdural hematoma associated with anti-aggregation therapy.
Topics: Aged; Aspirin; Clopidogrel; Diuretics, Osmotic; Female; Fibrin Fibrinogen Degradation Products; Follow-Up Studies; Hematoma, Subdural, Chronic; Humans; Mannitol; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Remission, Spontaneous; Ticlopidine; Tomography, X-Ray Computed | 2014 |
Chronic treatment with ticagrelor limits myocardial infarct size: an adenosine and cyclooxygenase-2-dependent effect.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Aspirin; Cardiotonic Agents; Clopidogrel; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Evaluation, Preclinical; Enzyme Induction; Lipoxins; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Nitric Oxide Synthase Type III; Pyrazoles; Quinazolines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; Ticagrelor; Ticlopidine; Triazoles; Up-Regulation | 2014 |
An atypical presentation of an extremely late stent thrombosis after more than 7 years (2634 days) of DES implantation in a patient without obvious risk factors on regular dual antiplatelet therapy.
Topics: Aspirin; Clopidogrel; Coronary Angiography; Coronary Thrombosis; Drug Therapy, Combination; Drug-Eluting Stents; Follow-Up Studies; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Complications; Risk Factors; Ticlopidine; Time Factors | 2014 |
Association between silent embolic cerebral infarction and continuous increase of P2Y12 reaction units after neurovascular stenting.
Topics: Aspirin; Cerebral Infarction; Clopidogrel; Drug Resistance; Endovascular Procedures; Female; Humans; Intracranial Embolism; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Purinergic P2Y Receptor Antagonists; Stents; Ticlopidine | 2014 |
Salvianolic acid B inhibits platelets as a P2Y12 antagonist and PDE inhibitor: evidence from clinic to laboratory.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Benzofurans; Blood Platelets; Clopidogrel; Drugs, Chinese Herbal; Humans; Male; Middle Aged; Phosphodiesterase Inhibitors; Platelet Activation; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Salvia miltiorrhiza; Ticlopidine | 2014 |
Lower GI bleeding risk of nonsteroidal anti-inflammatory drugs and antiplatelet drug use alone and the effect of combined therapy.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Clopidogrel; Colonic Diseases; Colonoscopy; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Rectal Diseases; Risk Factors; Ticlopidine | 2014 |
Short bowel syndrome and clopidogrel non-responsiveness: a new indication for platelet aggregometry?
Topics: Adenosine; Aged; Aspirin; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Female; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Short Bowel Syndrome; Ticagrelor; Ticlopidine | 2014 |
Acute Carotid Artery Stent Thrombosis Due to Dual Antiplatelet Resistance.
Topics: Acute Disease; Aged; Aspirin; Carotid Artery Thrombosis; Carotid Artery, Internal; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Hemiplegia; Humans; Male; Platelet Aggregation Inhibitors; Stents; Stroke; Ticlopidine; Tomography, X-Ray Computed | 2015 |
Global platelet hyperreactivity and elevated C-reactive protein levels predict long term mortality in STEMI patients.
Topics: Aged; Aspirin; Blood Platelets; C-Reactive Protein; Clopidogrel; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Function Tests; Prognosis; Stents; Ticlopidine | 2014 |
[Long-term cost-effectiveness of ticagrelor versus clopidogrel in acute coronary syndrome in Spain].
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Clopidogrel; Cost-Benefit Analysis; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Quality of Life; Spain; Ticagrelor; Ticlopidine; Time Factors | 2014 |
Impact of aspirin and clopidogrel interruption on platelet function in patients undergoing major vascular surgery.
Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Preoperative Period; Ticlopidine; Vascular Surgical Procedures; Withholding Treatment | 2014 |
Safety of low-dose aspirin in endovascular treatment for intracranial atherosclerotic stenosis.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Constriction, Pathologic; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine | 2014 |
Age-related prevalence of diabetes mellitus, cardiovascular disease and anticoagulation therapy use in a urolithiasis population and their effect on outcomes: the Clinical Research Office of the Endourological Society Ureteroscopy Global Study.
Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Comorbidity; Coumarins; Diabetes Mellitus; Female; Humans; Hypertension; Kidney Calculi; Male; Middle Aged; Obesity; Platelet Aggregation Inhibitors; Postoperative Complications; Postoperative Hemorrhage; Prevalence; Prospective Studies; Risk Factors; Ticlopidine; Treatment Outcome; Ureteral Calculi; Ureteroscopy; Urolithiasis; Young Adult | 2015 |
Comparison of the effect of CYP2C19 polymorphism on clinical outcome between acute coronary syndrome and stable angina.
Topics: Acute Coronary Syndrome; Aged; Alleles; Angina, Stable; Aspirin; Blood Platelets; Clopidogrel; Cytochrome P-450 CYP2C19; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Phenotype; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Ticlopidine; Treatment Outcome | 2015 |
Perioperative aspirin: to give or not to give?
Topics: Aspirin; Blood Transfusion; Coronary Artery Bypass; Coronary Disease; Female; Fibrinolytic Agents; Hemorrhage; Heparin, Low-Molecular-Weight; Hip Fractures; Humans; Lumbar Vertebrae; Male; Orthopedic Procedures; Pancreatectomy; Perioperative Period; Platelet Aggregation Inhibitors; Postoperative Care; Postoperative Hemorrhage; Preoperative Care; Prostatectomy; Prostatic Neoplasms; Robotics; Spinal Fusion; Ticlopidine | 2014 |
The significance of platelet count in traumatic brain injury patients on antiplatelet therapy.
Topics: Aged; Aspirin; Brain Injuries; Clopidogrel; Female; Humans; Intracranial Hemorrhages; Male; Platelet Aggregation Inhibitors; Platelet Count; Prospective Studies; ROC Curve; Ticlopidine; Tomography, X-Ray Computed | 2014 |
[Clinical impact of dual antiplatelet therapy on peptic ulcer disease].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Humans; Incidence; Male; Middle Aged; Peptic Ulcer; Platelet Aggregation Inhibitors; Proportional Hazards Models; Proton Pump Inhibitors; Retrospective Studies; Risk Factors; Ticlopidine | 2014 |
Effects of new regional cooperative rescue model on patients with ST-elevation myocardial infarction.
Topics: Aged; Aspirin; Clopidogrel; Electrocardiography; Emergency Medical Services; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Thrombolytic Therapy; Ticlopidine; Treatment Outcome | 2014 |
Aspirin treatment and outcomes after percutaneous coronary intervention: results of the ISAR-ASPI registry.
Topics: Aged; Aspirin; Biomarkers; Clopidogrel; Female; Humans; Incidence; Male; Middle Aged; Odds Ratio; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prognosis; Proportional Hazards Models; Registries; Stents; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2014 |
Aspirin treatment and outcomes in patients undergoing percutaneous coronary intervention: is there a role for pharmacodynamic testing?
Topics: Aspirin; Clopidogrel; Female; Humans; Male; Percutaneous Coronary Intervention; Ticlopidine | 2014 |
Validation of acute myocardial infarction cases in the national health insurance research database in taiwan.
Topics: Aged; Aged, 80 and over; Aspirin; Clinical Coding; Clopidogrel; Cross-Sectional Studies; Databases, Factual; Female; Humans; Male; Middle Aged; Myocardial Infarction; National Health Programs; Platelet Aggregation Inhibitors; Reproducibility of Results; Taiwan; Ticlopidine | 2014 |
Impaired responsiveness to the platelet P2Y12 receptor antagonist clopidogrel in patients with type 2 diabetes and coronary artery disease.
Topics: Adult; Aged; Aspirin; Clopidogrel; Cohort Studies; Coronary Artery Disease; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Purinergic P2Y Receptor Antagonists; Reference Values; Risk Assessment; Ticlopidine; Treatment Outcome | 2014 |
Impact of clopidogrel plus aspirin versus aspirin alone on the progression of native coronary artery disease after bypass surgery: analysis from the Clopidogrel After Surgery for Coronary Artery DiseasE (CASCADE) randomized trial.
Topics: Aged; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease; Coronary Restenosis; Coronary Stenosis; Diabetes Complications; Disease Progression; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Middle Aged; Multicenter Studies as Topic; Platelet Aggregation Inhibitors; Postoperative Complications; Randomized Controlled Trials as Topic; Risk Factors; Ticlopidine | 2014 |
Bleeding complication with dual antiplatelet therapy: spontaneous uvula hematoma.
Topics: Aged, 80 and over; Aspirin; Clopidogrel; Coronary Disease; Drug Interactions; Hematoma; Humans; Laryngoscopy; Male; Metoprolol; Platelet Aggregation Inhibitors; Ticlopidine; Uvula | 2014 |
Pirfenidone for idiopathic pulmonary fibrosis, thrombocytosis in chronic obstructive pulmonary disease exacerbations, and a longitudinal study on e-cigarettes.
Topics: Antifibrinolytic Agents; Aspirin; Drug Delivery Systems; Enzyme Inhibitors; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Nicotine; Platelet Aggregation Inhibitors; Pulmonary Disease, Chronic Obstructive; Pyridones; Smoking; Smoking Cessation; Thrombocytosis; Ticlopidine; Tobacco Use Cessation Devices | 2014 |
PRASFIT-ACS: important evidence against a "one-guideline-fits-all-races" approach to antiplatelet therapy.
Topics: Aspirin; Humans; Piperazines; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Thiophenes; Ticlopidine | 2014 |
PRASFIT-ACS: important evidence against a "one-guideline-fits-all-races" approach to antiplatelet therapy.
Topics: Aspirin; Humans; Piperazines; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Thiophenes; Ticlopidine | 2014 |
Intracranial hemorrhage during dual antiplatelet therapy after percutaneous left atrial appendage closure.
Topics: Aged; Aspirin; Atrial Appendage; Atrial Fibrillation; Clopidogrel; Drug Therapy, Combination; Humans; Intracranial Hemorrhages; Male; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2014 |
Assessment of the prophylactic role of aspirin and/or clopidogrel on experimentally induced acute myocardial infarction in hypercholesterolemic rats.
Topics: Animals; Aspirin; C-Reactive Protein; Cholesterol; Clopidogrel; Creatine Kinase; Diet, High-Fat; Drug Synergism; Drug Therapy, Combination; Hypercholesterolemia; Isoproterenol; L-Lactate Dehydrogenase; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Rats; Serum Amyloid P-Component; Ticlopidine; Transforming Growth Factor beta1; Triglycerides | 2014 |
Analysis of periinterventional complications of intracranial angioplasty and stenting: a single center experience.
Topics: Aged; Angioplasty; Aspirin; Blood Vessel Prosthesis Implantation; Clopidogrel; Diabetes Complications; Female; Humans; Hyperlipidemias; Hypertension; Intracranial Arteriosclerosis; Male; Middle Aged; Platelet Aggregation Inhibitors; Reperfusion Injury; Retrospective Studies; Stents; Stroke; Ticlopidine | 2014 |
2014 focused update of the Canadian Cardiovascular Society Guidelines for the management of atrial fibrillation.
Topics: Algorithms; Anticoagulants; Antithrombins; Aspirin; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Canada; Clopidogrel; Comorbidity; Dabigatran; Electric Countershock; Humans; Renal Insufficiency, Chronic; Risk Assessment; Stroke; Ticlopidine | 2014 |
Incidence of intracranial hemorrhage and outcomes after ground-level falls in geriatric trauma patients taking preinjury anticoagulants and antiplatelet agents.
Topics: Accidental Falls; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Clopidogrel; Female; Humans; Intracranial Hemorrhages; Logistic Models; Male; Multivariate Analysis; Platelet Aggregation Inhibitors; Registries; Retrospective Studies; Risk Assessment; Risk Factors; Ticlopidine; Warfarin | 2014 |
Does clopidogrel with aspirin after acute minor stroke or transient ischemic attack increase the risk of cerebral hemorrhage?
Topics: Aspirin; Cerebral Hemorrhage; Clopidogrel; Humans; Ischemic Attack, Transient; Male; Middle Aged; Ticlopidine | 2014 |
Safety and efficacy of in-hospital clopidogrel-to-prasugrel switching in patients with acute coronary syndrome. An analysis from the 'real world'.
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Drug Substitution; Female; Hemorrhage; Humans; Male; Middle Aged; Prasugrel Hydrochloride; Receptors, Purinergic P2Y12; Sex Factors; Thrombosis; Ticlopidine | 2015 |
Perioperative management of oral antiplatelet therapy and clinical outcomes in coronary stent patients undergoing surgery. Results of a multicentre registry.
Topics: Administration, Oral; Aged; Angina, Stable; Aspirin; Body Mass Index; Clopidogrel; Drug-Eluting Stents; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Ischemia; Odds Ratio; Percutaneous Coronary Intervention; Perioperative Period; Platelet Aggregation Inhibitors; Prevalence; Registries; Regression Analysis; Retrospective Studies; Risk Factors; Stents; Ticlopidine; Treatment Outcome | 2015 |
Precision and reliability of 5 platelet function tests in healthy volunteers and donors on daily antiplatelet agent therapy.
Topics: Arachidonic Acid; Aspirin; Clopidogrel; Female; Healthy Volunteers; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Reproducibility of Results; Sensitivity and Specificity; Ticlopidine | 2014 |
Evaluation of resistance to anti-platelet therapy in patients with coronary heart disease in a developing country.
Topics: Aspirin; Blood Platelets; Clopidogrel; Coronary Disease; Developing Countries; Drug Resistance; Hospitals, University; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Saudi Arabia; Ticlopidine; Time Factors; Treatment Outcome | 2014 |
Contemporary use of dual antiplatelet therapy for preventing cardiovascular events.
Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Female; Humans; Male; Platelet Aggregation Inhibitors; Practice Patterns, Physicians'; Retrospective Studies; Risk Factors; Secondary Prevention; Ticlopidine | 2014 |
Dental extractions and risk of bleeding in patients taking single and dual antiplatelet treatment.
Topics: Absorbable Implants; Aged; Aspirin; Clopidogrel; Collagen; Ecchymosis; Female; Hematoma; Hemostasis, Surgical; Hemostatic Techniques; Humans; Male; Middle Aged; Oral Hemorrhage; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Prasugrel Hydrochloride; Prospective Studies; Risk Factors; Surgical Sponges; Suture Techniques; Ticlopidine; Time Factors; Tooth Extraction | 2015 |
[Does dual antiplatelet therapy increase the risk of peptic ulcer disease?].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Peptic Ulcer; Platelet Aggregation Inhibitors; Ticlopidine | 2014 |
Spontaneous coronary artery dissection: a complete resolution with medical treatment.
Topics: Adult; Aspirin; Clopidogrel; Coronary Angiography; Coronary Vessel Anomalies; Fibrinolytic Agents; Heparin, Low-Molecular-Weight; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine; Vascular Diseases | 2014 |
Relation between the Change in Mean Platelet Volume and Clopidogrel Resistance in Patients Undergoing Percutaneous Coronary Intervention.
Topics: Aged; Aspirin; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Mean Platelet Volume; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Retrospective Studies; Sensitivity and Specificity; Ticlopidine; Treatment Outcome | 2015 |
Adherence to antiplatelet therapy after percutaneous coronary intervention: a population study in a region of Italy.
Topics: Adult; Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Female; Humans; Italy; Longitudinal Studies; Male; Medication Adherence; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Complications; Ticlopidine | 2015 |
Clopidogrel: A multifaceted affair.
Topics: Aspirin; Biological Availability; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Ticlopidine | 2015 |
Statistical Perspectives on Subgroup Analysis: Testing for Heterogeneity and Evaluating Error Rate for the Complementary Subgroup.
Topics: Algorithms; Antibiotics, Antineoplastic; Antineoplastic Agents; Aspirin; Clinical Trials as Topic; Clinical Trials, Phase III as Topic; Clopidogrel; Doxorubicin; Female; Humans; Ischemia; Ovarian Neoplasms; Platelet Aggregation Inhibitors; Reproducibility of Results; Research Design; Sample Size; Ticlopidine; Topotecan | 2015 |
Influence of race and sex on thrombogenicity in a large cohort of coronary artery disease patients.
Topics: Aged; Aspirin; Cardiac Catheterization; Chi-Square Distribution; Clopidogrel; Cohort Studies; Coronary Angiography; Coronary Artery Disease; Female; Follow-Up Studies; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation; Platelet Function Tests; Racial Groups; Risk Assessment; Sex Factors; Thrombelastography; Thrombosis; Ticlopidine; Treatment Outcome | 2014 |
Platelet function assays--not all are created equal.
Topics: Aspirin; Clopidogrel; Female; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2014 |
Very late bioresorbable vascular scaffold thrombosis following discontinuation of antiplatelet therapy.
Topics: Absorbable Implants; Adenosine; Adult; Aspirin; Blood Vessel Prosthesis; Clopidogrel; Graft Occlusion, Vascular; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Stents; Ticagrelor; Ticlopidine; Tirofiban; Tissue Scaffolds; Tyrosine | 2015 |
Association of plasma miR-223 and platelet reactivity in patients with coronary artery disease on dual antiplatelet therapy: A preliminary report.
Topics: Aged; Aspirin; Biomarkers; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; MicroRNAs; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2015 |
Dipstick proteinuria is an independent predictor of high on treatment platelet reactivity in patients on clopidogrel, but not aspirin, admitted for major adverse cardiovascular events.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Female; Humans; Male; Middle Aged; Odds Ratio; Patient Admission; Patient Outcome Assessment; Platelet Function Tests; Proteinuria; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Ticlopidine | 2015 |
Individualising dual antiplatelet therapy after percutaneous coronary intervention: the IDEAL-PCI registry.
Topics: Acute Coronary Syndrome; Adenosine; Aged; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Clopidogrel; Cohort Studies; Coronary Artery Disease; Female; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Precision Medicine; Prospective Studies; Registries; Stents; Thiophenes; Ticagrelor; Ticlopidine | 2014 |
Outcome of patients on oral anticoagulation undergoing coronary artery stenting: data from discharge to 12 months in the Warfarin and Coronary Stenting (WAR-STENT) Registry.
Topics: Administration, Oral; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Databases, Bibliographic; Drug Therapy, Combination; Drug-Eluting Stents; Follow-Up Studies; Hemorrhage; Prospective Studies; Registries; Ticlopidine; Treatment Outcome; Warfarin | 2014 |
No benefit to prolonged dual antiplatelet therapy after drug-eluting stent placement.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine; Treatment Outcome | 2014 |
Influence of dual antiplatelet therapy on mean platelet volume in patients with coronary artery disease undergoing percutaneous coronary intervention.
Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Monitoring; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Male; Mean Platelet Volume; Percutaneous Coronary Intervention; Platelet Activation; Platelet Aggregation Inhibitors; Predictive Value of Tests; Reproducibility of Results; Retrospective Studies; Ticlopidine; Time Factors; Treatment Outcome | 2016 |
Kounis syndrome secondary to food allergy.
Topics: Acute Coronary Syndrome; Adrenal Cortex Hormones; Anti-Allergic Agents; Aspirin; Clopidogrel; Electrocardiography; Female; Fibrinolytic Agents; Food Hypersensitivity; Heparin, Low-Molecular-Weight; Humans; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome; Urticaria | 2014 |
Optimising pharmacotherapy for secondary prevention of non-invasively managed acute coronary syndrome.
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anticholesteremic Agents; Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Thrombosis; Fibrinolytic Agents; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Secondary Prevention; Ticlopidine | 2014 |
Roles of the red cell distribution width and neutrophil/lymphocyte ratio in predicting thrombolysis failure in patients with an ST-segment elevation myocardial infarction.
Topics: Aged; Aspirin; Clopidogrel; Coronary Angiography; Drug Therapy, Combination; Electrocardiography; Erythrocyte Indices; Female; Fibrinolytic Agents; Humans; Leukocyte Count; Lymphocyte Count; Male; Middle Aged; Myocardial Infarction; Neutrophils; Percutaneous Coronary Intervention; Prognosis; Retrospective Studies; ROC Curve; Salvage Therapy; Sensitivity and Specificity; Tenecteplase; Thrombolytic Therapy; Ticlopidine; Tissue Plasminogen Activator; Treatment Failure | 2015 |
Dual antiplatelet therapy after drug-eluting stents--how long to treat?
Topics: Aspirin; Clopidogrel; Drug-Eluting Stents; Female; Humans; Male; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Thrombosis; Ticlopidine | 2014 |
Antiplatelet therapy: risks and benefits of extended DAPT after stenting.
Topics: Aspirin; Cardiovascular Diseases; Drug-Eluting Stents; Female; Humans; Male; Piperazines; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Thiophenes; Thrombosis; Ticlopidine | 2015 |
Blood pressure control after stroke: too little, too late, or too soon to tell?
Topics: Aspirin; Blood Pressure; Clopidogrel; Cognition; Female; Humans; Male; Platelet Aggregation Inhibitors; Stroke, Lacunar; Ticlopidine | 2014 |
A constrained heart: a case of sudden onset unrelenting chest pain.
Topics: Analgesics, Opioid; Aspirin; Chest Pain; Clopidogrel; Coronary Angiography; Drug Therapy, Combination; Echocardiography; Electrocardiography; Heart Defects, Congenital; Humans; Male; Middle Aged; Morphine; Nitroglycerin; Pericardium; Platelet Aggregation Inhibitors; Ticlopidine; Tomography, X-Ray Computed; Vasodilator Agents | 2014 |
Letter by Sardar et al regarding article, "optimal duration of dual antiplatelet therapy after drug-eluting stent implantation: a randomized, controlled trial".
Topics: Angioplasty, Balloon, Coronary; Aspirin; Coronary Artery Disease; Drug-Eluting Stents; Female; Humans; Male; Ticlopidine | 2014 |
Response to letter regarding article, "optimal duration of dual antiplatelet therapy after drug-eluting stent implantation: a randomized, controlled trial".
Topics: Angioplasty, Balloon, Coronary; Aspirin; Coronary Artery Disease; Drug-Eluting Stents; Female; Humans; Male; Ticlopidine | 2014 |
Concomitant use of warfarin and ticagrelor as an alternative to triple antithrombotic therapy after an acute coronary syndrome.
Topics: Acute Coronary Syndrome; Adenosine; Aged; Aged, 80 and over; Aspirin; Atrial Fibrillation; Clopidogrel; Drug Therapy, Combination; Female; Fibrinolytic Agents; Hemorrhage; Humans; Male; Middle Aged; Retrospective Studies; Risk Factors; Thrombosis; Ticagrelor; Ticlopidine; Treatment Outcome; Warfarin | 2015 |
Endovascular treatment of internal carotid artery pseudo-aneurysm presenting with epistaxis. A case report.
Topics: Angiography, Digital Subtraction; Aspirin; Carotid Artery Injuries; Carotid Artery, Internal; Clopidogrel; Endovascular Procedures; Epistaxis; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Recurrence; Stents; Ticlopidine; Treatment Outcome | 2014 |
Unusual cause of aborted sudden cardiac death in a teen athlete: homozygosity for the 4G allele of the plasminogen activase inhibitor type 1 gene.
Topics: Adolescent; Alleles; Aspirin; Athletes; Cardiac Catheterization; Clopidogrel; Death, Sudden, Cardiac; Homozygote; Humans; Male; Plasminogen Activator Inhibitor 1; Platelet Aggregation Inhibitors; Ticlopidine | 2015 |
Patterns of Antiplatelet Therapy in Patients Who Have Experienced an Acute Coronary Event: A Descriptive Study in UK Primary Care.
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Cohort Studies; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Primary Health Care; Proton Pump Inhibitors; Retrospective Studies; Secondary Prevention; Stroke; Ticlopidine; United Kingdom | 2015 |
Assessment of risk of late rectal bleeding for patients with prostate cancer started on anticoagulation before or after radiation treatment.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Clopidogrel; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Prostatic Neoplasms; Radiation Injuries; Radiotherapy, Conformal; Radiotherapy, Intensity-Modulated; Rectum; Retrospective Studies; Risk; Telangiectasis; Ticlopidine; Warfarin | 2014 |
Web Exclusives. The consult guys--balancing the medication portfolio 5 years after a heart attack.
Topics: Adrenergic beta-1 Receptor Antagonists; Aspirin; Clopidogrel; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Metoprolol; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors | 2014 |
[Factors influencing platelet aggregation in patients with acute coronary syndrome].
Topics: Acute Coronary Syndrome; Aspirin; Blood Coagulation Tests; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Administration Schedule; Drug Monitoring; Female; Humans; Male; Mean Platelet Volume; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Statistics as Topic; Ticlopidine; Time Factors | 2014 |
Effect of rebamipide on gastric bleeding and ulcerogenic responses induced by aspirin plus clopidogrel under stimulation of acid secretion in rats.
Topics: Alanine; Animals; Anti-Ulcer Agents; Aspirin; Clopidogrel; Disease Models, Animal; Gastric Acid; Gastric Mucosa; Gastrointestinal Hemorrhage; Male; Platelet Aggregation Inhibitors; Quinolones; Rats, Sprague-Dawley; Stomach Ulcer; Ticlopidine; Treatment Outcome | 2014 |
From innovation to implementation: optimizing long-term outcomes after TAVR.
Topics: Aortic Valve Stenosis; Aspirin; Clopidogrel; Female; Hemorrhage; Humans; Male; Ticlopidine; Transcatheter Aortic Valve Replacement | 2014 |
[Analysis of traditional Chinese medicine syndrome, traditional Chinese medicine and western medicine in 84 697 patients with coronary heart disease based on big data].
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Coronary Disease; Drugs, Chinese Herbal; Female; Humans; Isosorbide Dinitrate; Male; Medicine, Chinese Traditional; Middle Aged; Ticlopidine | 2014 |
Aspirin is associated with an increased risk of subdural hematoma in normal-pressure hydrocephalus patients following shunt implantation.
Topics: Aged; Aged, 80 and over; Aspirin; Cerebrospinal Fluid Shunts; Clopidogrel; Female; Fibrinolytic Agents; Hematoma, Subdural; Humans; Hydrocephalus, Normal Pressure; Male; Middle Aged; Risk Factors; Ticlopidine | 2015 |
Liquid Chromatographic Method for Simultaneous Quantitation of Clopidogrel, Aspirin and Atorvastatin in Rat Plasma and Its Application to the Pharmacokinetic Study.
Topics: Animals; Anticholesteremic Agents; Aspirin; Atorvastatin; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Clopidogrel; Limit of Detection; Male; Platelet Aggregation Inhibitors; Rats; Reproducibility of Results; Ticlopidine | 2015 |
[Changes in the diagnosis and treatment of hospitalized patients with acute coronary syndrome from 2006 to 2012 in China].
Topics: Acute Coronary Syndrome; Aged; Aspirin; Cardiovascular Diseases; China; Clopidogrel; Female; Hospitalization; Hospitals; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Ticlopidine | 2014 |
Balancing the risks of bleeding and stent thrombosis: a decision analytic model to compare durations of dual antiplatelet therapy after drug-eluting stents.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Decision Support Techniques; Drug-Eluting Stents; Female; Hemorrhage; Humans; Male; Markov Chains; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Complications; Risk Adjustment; Risk Assessment; Thrombosis; Ticlopidine; Time; Treatment Outcome | 2015 |
High on-treatment platelet reactivity in transcatheter aortic valve implantation patients.
Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Female; Humans; Ischemia; Male; Platelet Aggregation Inhibitors; Ticlopidine; Transcatheter Aortic Valve Replacement | 2015 |
Response to dual antiplatelet therapy in patients with peripheral artery occlusive disease suffering from critical limb ischemia.
Topics: Aged; Aged, 80 and over; Area Under Curve; Aspirin; Clopidogrel; Critical Illness; Drug Resistance; Drug Therapy, Combination; Female; Germany; Humans; Ischemia; Male; Middle Aged; Peripheral Arterial Disease; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prospective Studies; ROC Curve; Ticlopidine; Time Factors; Treatment Outcome | 2014 |
Triple therapy for atrial fibrillation and ACS with or without PCI: don't drop aspirin just yet.
Topics: Aspirin; Atrial Fibrillation; Humans; Percutaneous Coronary Intervention; Ticlopidine; Vitamin K | 2015 |
Reply: Triple therapy for atrial fibrillation and ACS with or without PCI: don't drop aspirin just yet.
Topics: Aspirin; Atrial Fibrillation; Humans; Percutaneous Coronary Intervention; Ticlopidine; Vitamin K | 2015 |
Biodegradable polymer biolimus-eluting stent versus durable polymer everolimus-eluting stent in patients with acute myocardial infarction.
Topics: Absorbable Implants; Aged; Aspirin; Clopidogrel; Coronary Thrombosis; Drug-Eluting Stents; Everolimus; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Prospective Studies; Prosthesis Design; Sirolimus; Ticlopidine; Treatment Outcome | 2015 |
Induction of both P-glycoprotein and specific cytochrome P450 by aspirin eventually does not alter the antithrombotic effect of clopidogrel.
Topics: Aspirin; ATP Binding Cassette Transporter, Subfamily B, Member 1; Fibrinolytic Agents; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine | 2015 |
Response to "Induction of both P-glycoprotein and specific cytochrome P450 by aspirin eventually does not alter the antithrombotic effect of clopidogrel".
Topics: Aspirin; ATP Binding Cassette Transporter, Subfamily B, Member 1; Fibrinolytic Agents; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine | 2015 |
Dual antiplatelet therapy in patients with a long coronary artery lesion over 30 mm: Determinants and impact on prognosis.
Topics: Administration, Inhalation; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Drug-Eluting Stents; Female; Humans; Kaplan-Meier Estimate; Linear Models; Male; Middle Aged; Multivariate Analysis; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proportional Hazards Models; Retrospective Studies; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome | 2015 |
Sellar and parasellar tumor removal without discontinuing antithrombotic therapy.
Topics: Adenoma; Aged; Aspirin; Central Nervous System Cysts; Clopidogrel; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Neurosurgical Procedures; Pituitary Neoplasms; Postoperative Period; Ticlopidine; Treatment Outcome | 2015 |
Effect of proton-pump inhibitors on the risk of lower gastrointestinal bleeding associated with NSAIDs, aspirin, clopidogrel, and warfarin.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Case-Control Studies; Clopidogrel; Drug Interactions; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Proton Pump Inhibitors; Ticlopidine; Warfarin; Young Adult | 2015 |
How should I treat subacute stent thrombosis in the context of brain haemorrhage with abciximab?
Topics: Abciximab; Antibodies, Monoclonal; Aspirin; Cerebral Hemorrhage; Clopidogrel; Embolic Protection Devices; Female; Humans; Immunoglobulin Fab Fragments; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Stents; Suction; Thrombosis; Ticlopidine | 2015 |
New approach application of data transformation in mean centering of ratio spectra method.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Aspirin; Atorvastatin; Clopidogrel; Normal Distribution; Platelet Aggregation Inhibitors; Spectrophotometry; Ticlopidine | 2015 |
Thrombotic complications associated with early and late nonadherence to dual antiplatelet therapy.
Topics: Aged; Aspirin; Cardiovascular Agents; Clopidogrel; Coronary Thrombosis; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Humans; Kaplan-Meier Estimate; Logistic Models; Male; Medication Adherence; Middle Aged; Multivariate Analysis; Myocardial Infarction; Odds Ratio; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Prospective Studies; Prosthesis Design; Registries; Risk Factors; Sirolimus; Ticlopidine; Time Factors; Treatment Outcome | 2015 |
Preinjury warfarin, but not antiplatelet medications, increases mortality in elderly traumatic brain injury patients.
Topics: Administration, Oral; Aged; Anticoagulants; Aspirin; Brain Injuries; Clopidogrel; Female; Humans; Intracranial Hemorrhages; Length of Stay; Male; Platelet Aggregation Inhibitors; Retrospective Studies; Survival Rate; Ticlopidine; Tomography, X-Ray Computed; Trauma Severity Indices; Warfarin | 2015 |
Effect of clinical factors and gene polymorphism of CYP2C19*2, *17 and CYP4F2*3 on early stent thrombosis.
Topics: Aged; Aspirin; Case-Control Studies; Clopidogrel; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Female; Genotype; Humans; Logistic Models; Male; Middle Aged; Models, Genetic; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Risk Factors; Stents; Thrombosis; Ticlopidine | 2015 |
Dual Antiplatelet Therapy Duration Following Coronary Stenting. [Corrected].
Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Drug-Eluting Stents; Female; Hemorrhage; Humans; Male; Percutaneous Coronary Intervention; Ticlopidine | 2015 |
Plasma fibrin clot phenotype independently affects intracoronary thrombus ultrastructure in patients with acute myocardial infarction.
Topics: Aged; Aspirin; Blood Platelets; Chi-Square Distribution; Clopidogrel; Coronary Thrombosis; Coronary Vessels; Drug Therapy, Combination; Erythrocytes; Female; Fibrin; Fibrinolysis; Humans; Male; Microscopy, Electron, Scanning; Middle Aged; Multivariate Analysis; Myocardial Infarction; Percutaneous Coronary Intervention; Permeability; Phenotype; Platelet Aggregation; Platelet Aggregation Inhibitors; Porosity; Suction; Thrombectomy; Ticlopidine; Time Factors | 2015 |
Comment: TIA response to antiplatelets stratified by glycated albumin.
Topics: Aspirin; Clopidogrel; Female; Humans; Ischemic Attack, Transient; Male; Stroke; Ticlopidine | 2015 |
Prolonged dual antiplatelet therapy after drug-eluting stent reduces the risk of stent thrombosis and major cardiovascular events but increases the rate of bleeding.
Topics: Aspirin; Drug-Eluting Stents; Female; Humans; Male; Piperazines; Platelet Aggregation Inhibitors; Thiophenes; Thrombosis; Ticlopidine | 2015 |
[Triple anticoagulant therapy - now what can I give for pain?].
Topics: Aged; Analgesics; Anticoagulants; Aspirin; Back Pain; Benzimidazoles; beta-Alanine; Clopidogrel; Contraindications; Dabigatran; Drug Therapy, Combination; Germany; Hemorrhage; Humans; Male; Risk Factors; Stents; Ticlopidine | 2015 |
Investigation of possible prophylactic, renoprotective, and cardioprotective effects of thromboprophylactic drugs against ischemia-reperfusion injury.
Topics: Animals; Anticoagulants; Aryldialkylphosphatase; Aspirin; Cardiotonic Agents; Clopidogrel; Dipeptidases; Drug Evaluation, Preclinical; Enoxaparin; Femoral Artery; Heparin, Low-Molecular-Weight; Hindlimb; Kidney; Male; Malondialdehyde; Morpholines; Myocardium; Nitric Oxide; Oxidative Stress; Rats, Sprague-Dawley; Reperfusion Injury; Rivaroxaban; Thiophenes; Ticlopidine | 2015 |
Characterization of patients with angioscopically-detected in-stent mural thrombi – genetics of clopidogrel responsiveness and generations of drug-eluting stents.
Topics: Activation, Metabolic; Aged; Alleles; Angina Pectoris; Angioscopy; Aspirin; Clopidogrel; Coronary Angiography; Coronary Thrombosis; Cytochrome P-450 CYP2C19; Drug Resistance; Drug Therapy, Combination; Drug-Eluting Stents; Female; Genotype; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Proton Pump Inhibitors; Receptors, Purinergic P2Y12; Ticlopidine | 2015 |
Dual antiplatelet response during PCI: VerifyNow P2Y12 predicts myocardial necrosis and thromboxane B2 generation confirms wide variation in aspirin response.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Clopidogrel; Cohort Studies; Cross-Sectional Studies; Female; Humans; Male; Middle Aged; Myocardium; Necrosis; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Receptors, Purinergic P2Y12; Regression Analysis; Thromboxane B2; Ticlopidine | 2015 |
Angiographic and clinical results of everolimus-eluting stent utilization in saphenous vein graft lesions (ARES).
Topics: Aged; Aged, 80 and over; Angiography; Angioplasty, Balloon; Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Disease; Drug-Eluting Stents; Everolimus; Female; Graft Occlusion, Vascular; Humans; Male; Outcome Assessment, Health Care; Platelet Aggregation Inhibitors; Reoperation; Saphenous Vein; Ticlopidine | 2015 |
Clinical impact of dual antiplatelet therapy use in patients following everolimus-eluting stent implantation: insights from the SEEDS study.
Topics: Adolescent; Adult; Aged; Aspirin; Clopidogrel; Drug-Eluting Stents; Everolimus; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Sirolimus; Thrombosis; Ticlopidine; Treatment Outcome; Young Adult | 2015 |
Predictors of high on-aspirin platelet reactivity in high-risk vascular patients treated with single or dual antiplatelet therapy.
Topics: Adenosine; Aged; Aspirin; Cerebrovascular Disorders; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Fibrinogen; Humans; Male; Middle Aged; Piperazines; Platelet Activation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Predictive Value of Tests; Purinergic P2Y Receptor Antagonists; Retrospective Studies; Secondary Prevention; Thiophenes; Ticagrelor; Ticlopidine | 2015 |
Balancing the risks and benefits of dual platelet inhibition.
Topics: Adenosine; Aspirin; Drug-Eluting Stents; Female; Humans; Male; Piperazines; Platelet Aggregation Inhibitors; Thiophenes; Thrombosis; Ticagrelor; Ticlopidine | 2015 |
ACP journal club. Dual antiplatelets for 30 mo after drug-eluting stents reduced stent thrombosis and CV and cerebrovascular events.
Topics: Aspirin; Drug-Eluting Stents; Female; Humans; Male; Piperazines; Platelet Aggregation Inhibitors; Thiophenes; Thrombosis; Ticlopidine | 2015 |
Close encounters with errors of the second kind: evaluating risks and benefits of long-term dual antiplatelet therapy.
Topics: Acute Coronary Syndrome; Aspirin; Coronary Artery Disease; Female; Humans; Male; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2015 |
Cilostazol may prevent cardioembolic stroke in patients undergoing antiplatelet therapy.
Topics: Aged; Aspirin; Atrial Fibrillation; Cilostazol; Clopidogrel; Databases, Factual; Female; Fibrinolytic Agents; Humans; Incidence; Intracranial Embolism; Male; Multivariate Analysis; Platelet Aggregation Inhibitors; Retrospective Studies; Stroke; Tetrazoles; Ticlopidine | 2015 |
Effects of Paclitaxel on the Ability of Aspirin and Clopidogrel to Inhibit Platelet Aggregation.
Topics: Adenosine Diphosphate; Adult; Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Male; Paclitaxel; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; Young Adult | 2016 |
Does the response to aspirin and clopidogrel vary over 6 months in patients with ischemic heart disease?
Topics: Aged; Area Under Curve; Aspirin; Biomarkers; Blood Platelets; Clopidogrel; Drug Therapy, Combination; England; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prospective Studies; Receptors, Purinergic P2Y12; Reproducibility of Results; ROC Curve; Thrombelastography; Thromboxane B2; Ticlopidine; Time Factors; Treatment Outcome | 2015 |
Effect of Active Smoking on Comparative Efficacy of Antithrombotic Therapy in Patients With Atrial Fibrillation: The Loire Valley Atrial Fibrillation Project.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Case-Control Studies; Clopidogrel; Female; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Proportional Hazards Models; Smoking; Stroke; Thromboembolism; Ticlopidine; Warfarin | 2015 |
Whatever will be, will be: spontaneous chest wall hematoma with regular use of low-dose acetylsalicylic Acid.
Topics: Aspirin; Coronary Artery Disease; Hematoma; Humans; Male; Platelet Aggregation Inhibitors; Thoracic Wall; Ticlopidine | 2015 |
Duration of dual antiplatelet therapy after drug-eluting stents.
Topics: Aspirin; Drug-Eluting Stents; Female; Humans; Male; Piperazines; Platelet Aggregation Inhibitors; Thiophenes; Thrombosis; Ticlopidine | 2015 |
Duration of dual antiplatelet therapy after drug-eluting stents.
Topics: Aspirin; Drug-Eluting Stents; Female; Humans; Male; Piperazines; Platelet Aggregation Inhibitors; Thiophenes; Thrombosis; Ticlopidine | 2015 |
Duration of dual antiplatelet therapy after drug-eluting stents.
Topics: Aspirin; Drug-Eluting Stents; Female; Humans; Male; Piperazines; Platelet Aggregation Inhibitors; Thiophenes; Thrombosis; Ticlopidine | 2015 |
Duration of dual antiplatelet therapy after drug-eluting stents.
Topics: Aspirin; Drug-Eluting Stents; Female; Humans; Male; Piperazines; Platelet Aggregation Inhibitors; Thiophenes; Thrombosis; Ticlopidine | 2015 |
Duration of dual antiplatelet therapy after drug-eluting stents.
Topics: Aspirin; Drug-Eluting Stents; Female; Humans; Male; Piperazines; Platelet Aggregation Inhibitors; Thiophenes; Thrombosis; Ticlopidine | 2015 |
Duration of dual antiplatelet therapy after drug-eluting stents.
Topics: Aspirin; Drug-Eluting Stents; Female; Humans; Male; Piperazines; Platelet Aggregation Inhibitors; Thiophenes; Thrombosis; Ticlopidine | 2015 |
Aspirin 'resistance': impact on no-reflow, platelet and inflammatory biomarkers in diabetics after ST-segment elevation myocardial infarction.
Topics: Aged; Aspirin; Biomarkers; Clopidogrel; Diabetes Complications; Drug Resistance; Female; Humans; Inflammation; Male; Middle Aged; Myocardial Infarction; No-Reflow Phenomenon; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2015 |
Impact of prolonged dual antiplatelet therapy after acute myocardial infarction on 5-year mortality in the FAST-MI 2005 registry.
Topics: Aged; Aspirin; Clopidogrel; Drug-Eluting Stents; Female; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Prospective Studies; Registries; Ticlopidine; Time Factors | 2015 |
Accuracy of optical frequency domain imaging for evaluation of coronary adventitial vasa vasorum formation after stent implantation in pigs and humans - a validation study - .
Topics: Adventitia; Aged; Aged, 80 and over; Animals; Aspirin; Clopidogrel; Coronary Stenosis; Coronary Vessels; Disease Progression; Drug-Eluting Stents; Everolimus; Female; Humans; Interferometry; Male; Middle Aged; Neointima; Neovascularization, Physiologic; Platelet Aggregation Inhibitors; Postoperative Period; Prosthesis Implantation; Sirolimus; Stents; Swine; Swine, Miniature; Ticlopidine; Tomography, Optical Coherence; Vasa Vasorum; Vasculitis | 2015 |
Effects of Rivaroxaban on Platelet Activation and Platelet-Coagulation Pathway Interaction: In Vitro and In Vivo Studies.
Topics: Adenosine; Adult; Animals; Arteriovenous Shunt, Surgical; Aspirin; Blood Coagulation; Clopidogrel; Coronary Thrombosis; Dose-Response Relationship, Drug; Female; Humans; Male; Platelet Activation; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Rivaroxaban; Thrombin; Ticagrelor; Ticlopidine | 2015 |
Platelet transfusion reverses bleeding evoked by triple anti-platelet therapy including vorapaxar, a novel platelet thrombin receptor antagonist.
Topics: Animals; Aspirin; Bleeding Time; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Lactones; Macaca fascicularis; Platelet Aggregation Inhibitors; Platelet Transfusion; Pyridines; Receptors, Thrombin; Ticlopidine | 2015 |
Correlation Between SNPs in Candidate Genes and VerifyNow-Detected Platelet Responsiveness to Aspirin and Clopidogrel Treatment.
Topics: Aged; Asian People; Aspirin; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Female; Genotype; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Ticlopidine | 2015 |
Association of dual-antiplatelet therapy with reduced major adverse cardiovascular events in patients with symptomatic peripheral arterial disease.
Topics: Adult; Aged; Aged, 80 and over; Amputation, Surgical; Aspirin; California; Cardiovascular Diseases; Chi-Square Distribution; Clopidogrel; Critical Illness; Drug Therapy, Combination; Female; Humans; Intermittent Claudication; Ischemia; Kaplan-Meier Estimate; Male; Middle Aged; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Predictive Value of Tests; Propensity Score; Proportional Hazards Models; Registries; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome | 2015 |
Influence of Different β-Blockers on Platelet Aggregation in Patients With Coronary Artery Disease on Dual Antiplatelet Therapy.
Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Aspirin; Bisoprolol; Carbazoles; Carvedilol; Clopidogrel; Coronary Artery Disease; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Metoprolol; Middle Aged; Nebivolol; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Propanolamines; Prospective Studies; Ticlopidine; Treatment Outcome | 2016 |
Two young women with severe coronary arterial ostial narrowing: A potential subtype of Takayasu arteritis.
Topics: Adult; Aspirin; Clopidogrel; Coronary Angiography; Coronary Stenosis; Cyclophosphamide; Diagnosis, Differential; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Methylprednisolone; Monitoring, Physiologic; Platelet Aggregation Inhibitors; Rare Diseases; Sampling Studies; Takayasu Arteritis; Ticlopidine; Treatment Outcome; Young Adult | 2015 |
Impact of esomeprazole on platelet reactivity and clinical outcome according to CYP2C19 genotype in coronary heart disease patients during dual antiplatelet therapy.
Topics: Aged; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Coronary Disease; Cytochrome P-450 CYP2C19; Esomeprazole; Ethnicity; Female; Follow-Up Studies; Genotype; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Prospective Studies; Proton Pump Inhibitors; Ticlopidine; Treatment Outcome | 2015 |
When Is a Double Better Than a TRIPLE?: Stenting in Patients With Atrial Fibrillation.
Topics: Aspirin; Drug-Eluting Stents; Female; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine | 2015 |
Effectiveness of prolonged clopidogrel-based dual antiplatelet therapy after drug-eluting stent implantation: Evidence-based meta-analysis.
Topics: Aged; Aspirin; Clopidogrel; Coronary Restenosis; Drug Administration Schedule; Drug Combinations; Drug-Eluting Stents; Evidence-Based Medicine; Female; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prevalence; Risk Factors; Survival Rate; Ticlopidine; Treatment Outcome | 2015 |
Effects of anticoagulants on outcome of femoral neck fracture surgery.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Clopidogrel; Female; Femoral Neck Fractures; Humans; Male; Middle Aged; Postoperative Complications; Retrospective Studies; Ticlopidine; Warfarin | 2015 |
Clopidogrel is not associated with increased bleeding complications after full-mouth extraction: A retrospective study.
Topics: Aspirin; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Retrospective Studies; Ticlopidine; Time Factors; Tooth Extraction | 2015 |
Traditional clinical risk factors predict clopidogrel hypo-responsiveness in unselected patients undergoing non-emergent percutaneous coronary intervention.
Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine | 2016 |
Glanzmann's thrombasthenia: meeting the anticoagulation challenge.
Topics: Aminocaproic Acid; Aspirin; Clopidogrel; Factor VIIa; Hemorrhage; Humans; Isoantibodies; Male; Middle Aged; Platelet Transfusion; Recombinant Proteins; Thrombasthenia; Ticlopidine | 2015 |
Dual antiplatelet therapy tailored on platelet function test after coronary stent implantation: a real-world experience.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Blood Platelets; Clopidogrel; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Function Tests; Stents; Ticlopidine | 2015 |
Analysis of the Interaction between Clopidogrel, Aspirin, and Proton Pump Inhibitors Using the FDA Adverse Event Reporting System Database.
Topics: Adverse Drug Reaction Reporting Systems; Aspirin; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Embolism; Female; Gastrointestinal Hemorrhage; Humans; Male; Odds Ratio; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Risk Factors; Thrombosis; Ticlopidine; United States; United States Food and Drug Administration | 2015 |
Antithrombotic therapy after transcatheter aortic valve implantation.
Topics: Aortic Valve Stenosis; Aspirin; Cardiac Catheterization; Clopidogrel; Female; Heart Valve Prosthesis Implantation; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine | 2015 |
Antiplatelets Versus Anticoagulation for Cervical Arterial Dissection.
Topics: Anticoagulants; Aortic Dissection; Aspirin; Carotid Artery, Internal, Dissection; Cervical Vertebrae; Clopidogrel; Dipyridamole; Drug Administration Schedule; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stroke; Ticlopidine; Treatment Outcome; Vertebral Artery Dissection | 2015 |
Activated Hemostatic Biomarkers in Patients with Implanted Left Ventricle Assist Devices: Are Heparin and/or Clopidogrel Justified?
Topics: Adult; Anticoagulants; Aspirin; Biomarkers; Clopidogrel; Drug Therapy, Combination; Fibrin Fibrinogen Degradation Products; Fibrinogen; Heart Failure; Heart Ventricles; Heart-Assist Devices; Heparin; Humans; Male; Platelet Activation; Platelet Aggregation; Ticlopidine; Warfarin | 2015 |
Aspirin Treatment and Outcomes After Percutaneous Coronary Intervention: Results of the ISAR-ASPI Registry.
Topics: Aspirin; Female; Humans; Male; Percutaneous Coronary Intervention; Ticlopidine | 2015 |
Reply: Aspirin Treatment and Outcomes After Percutaneous Coronary Intervention: Results of the ISAR-ASPI Registry.
Topics: Aspirin; Female; Humans; Male; Percutaneous Coronary Intervention; Ticlopidine | 2015 |
Cardioembolic acute myocardial infarction associated with apical ballooning: Considerations.
Topics: Aged, 80 and over; Aspirin; Clopidogrel; Coronary Thrombosis; Drug Therapy, Combination; Echocardiography; Electrocardiography; Enoxaparin; Female; Humans; Myocardial Infarction; Takotsubo Cardiomyopathy; Ticlopidine | 2015 |
Clopidogrel versus aspirin in patients with recent ischemic stroke and established peripheral artery disease: an economic evaluation in a Chinese setting.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Cost-Benefit Analysis; Humans; Middle Aged; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Quality-Adjusted Life Years; Secondary Prevention; Stroke; Ticlopidine | 2015 |
Management and outcome of major bleeding in patients on triple therapy after coronary stenting. Clues from the WARfarin and coronary STENTing (WAR-STENT) registry.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Registries; Stents; Thrombosis; Ticlopidine; Treatment Outcome; Warfarin | 2015 |
Pre-procedural dual antiplatelet therapy and bleeding events following transcatheter aortic valve implantation (TAVI).
Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Female; Hemorrhage; Humans; Male; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine; Transcatheter Aortic Valve Replacement | 2015 |
Pre-treatment with dual antiplatelet therapy in patients with non-ST-segment elevation acute coronary syndromes undergoing percutaneous coronary intervention.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Australia; Clopidogrel; Female; Hemorrhage; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Complications; Registries; Ticlopidine; Treatment Outcome | 2015 |
Calcium-Channel Blockers Attenuate the Antiplatelet Effect of Clopidogrel.
Topics: Adenosine Diphosphate; Aged; Angioplasty; Aspirin; Calcium Channel Blockers; Clopidogrel; Dihydropyridines; Drug Interactions; Female; Flow Cytometry; Humans; Male; Middle Aged; P-Selectin; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Stents; Ticlopidine | 2015 |
Body Mass Index and Platelet Reactivity During Dual Antiplatelet Therapy With Clopidogrel or Ticagrelor.
Topics: Acute Coronary Syndrome; Adenosine; Aged; Aspirin; Blood Platelets; Body Mass Index; Clopidogrel; Cohort Studies; Drug Therapy, Combination; Female; Humans; Male; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticagrelor; Ticlopidine | 2015 |
Mean platelet volume and high-residual platelet reactivity in patients receiving dual antiplatelet therapy with clopidogrel or ticagrelor.
Topics: Acute Coronary Syndrome; Adenosine; Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Humans; Male; Mean Platelet Volume; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticagrelor; Ticlopidine | 2015 |
Assessing the Quality of Care for Patients With Acute Myocardial Infarction in China.
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; China; Clopidogrel; Coronary Angiography; Female; Hospital Mortality; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Quality Indicators, Health Care; Ticlopidine | 2015 |
How to test the effect of aspirin and clopidogrel in patients on dual antiplatelet therapy?
Topics: Aspirin; Case-Control Studies; Clopidogrel; Drug Interactions; Drug Monitoring; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2016 |
Interaction of Panax quinquefolius Saponin and Dual Antiplatelets on Vascular Endothelial Function in Rats with Acute Myocardial Infarction.
Topics: Animals; Aspirin; Clopidogrel; Coronary Vessels; Endothelial Cells; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Rats; Saponins; Ticlopidine; Ventricular Remodeling | 2015 |
Prediction of high risk of non-adherence to antiplatelet treatment.
Topics: Aged; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Humans; Male; Medication Adherence; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Poland; Prospective Studies; Ticlopidine | 2016 |
Clinical outcomes of multiple chronic total occlusions in coronary arteries according to three therapeutic strategies: Bypass surgery, percutaneous intervention and medication.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Occlusion; Coronary Vessels; Death; Female; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Registries; Retrospective Studies; Risk Factors; Stroke; Ticlopidine; Treatment Outcome | 2015 |
Duration of Dual Antiplatelet Therapy After Drug-eluting Stents Implantation: The Jury Is Still Out.
Topics: Aspirin; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors; Treatment Outcome | 2015 |
Redesigning TRACER trial after TRITON.
Topics: Acute Coronary Syndrome; Aspirin; Clinical Trials as Topic; Clopidogrel; Drug Evaluation; Drug Therapy, Combination; Hemorrhage; Humans; Lactones; Neoplasms; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Pyridines; Research Design; Ticlopidine | 2015 |
Comparison of Angiographic Outcomes of Side Branch Ostium at Bifurcation Coronary Lesion between Two-stent and One-stent Techniques.
Topics: Aspirin; Clopidogrel; Cohort Studies; Coronary Angiography; Coronary Vessels; Drug-Eluting Stents; Female; Heart; Heart Septal Defects, Atrial; Humans; Male; Middle Aged; Myocardial Revascularization; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Retrospective Studies; Ticlopidine; Treatment Outcome | 2015 |
Could perioperative bleeding complications be predicted using a platelet aggregation test?
Topics: Aspirin; Coronary Artery Bypass; Female; Humans; Male; Platelet Function Tests; Postoperative Hemorrhage; Thrombosis; Ticlopidine | 2015 |
Cytochrome P450 CYP 2C19*2 Associated with Adverse 1-Year Cardiovascular Events in Patients with Acute Coronary Syndrome.
Topics: Activation, Metabolic; Acute Coronary Syndrome; Aged; Alleles; Angina Pectoris; Aspirin; Clopidogrel; Coronary Restenosis; Coronary Thrombosis; Cytochrome P-450 CYP2C19; Drug Resistance; Drug Therapy, Combination; Female; Follow-Up Studies; Genetic Predisposition to Disease; Genotype; Humans; Incidence; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Prodrugs; Prognosis; Prospective Studies; Recurrence; Stents; Ticlopidine; Treatment Outcome | 2015 |
Evaluation of S100B in the diagnosis of suspected intracranial hemorrhage after minor head injury in patients who are receiving platelet aggregation inhibitors and in patients 65 years of age and older.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Biomarkers; Clopidogrel; Craniocerebral Trauma; Female; Glasgow Coma Scale; Humans; Intracranial Hemorrhage, Traumatic; Male; Middle Aged; Platelet Aggregation Inhibitors; Predictive Value of Tests; Prospective Studies; S100 Calcium Binding Protein beta Subunit; Ticlopidine | 2015 |
Individualised dual antiplatelet therapy in a patient with short bowel syndrome after acute myocardial infarction with coronary artery stenting.
Topics: Abdominal Pain; Anterior Wall Myocardial Infarction; Aspirin; Clopidogrel; Cytochrome P-450 CYP2C19; Fatal Outcome; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Precision Medicine; Short Bowel Syndrome; Stents; Ticlopidine | 2015 |
Perioperative Management of Antiplatelets and Anticoagulants Among Patients Undergoing Elective Transurethral Resection of the Prostate--A Single Institution Experience.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Aspirin, Dipyridamole Drug Combination; Clopidogrel; Elective Surgical Procedures; Enoxaparin; Hemorrhage; Humans; Male; Middle Aged; Perioperative Care; Platelet Aggregation Inhibitors; Postoperative Complications; Prostate; Prostatic Hyperplasia; Retrospective Studies; Thromboembolism; Ticlopidine; Transurethral Resection of Prostate; Victoria; Warfarin; Withholding Treatment | 2015 |
[The ISAR-SAFE study].
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Disease; Coronary Restenosis; Drug Administration Schedule; Drug-Eluting Stents; Humans; Platelet Aggregation Inhibitors; Postoperative Complications; Purinergic P2Y Receptor Antagonists; Randomized Controlled Trials as Topic; Research Design; Risk; Thrombosis; Ticlopidine | 2015 |
[SECONDARY PREVENTION IN PATIENTS WITH ACUTE CORONARY SYNDROME HOSPITALIZED IN INTERNAL MEDICINE DEPARTMENTS].
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Atrial Fibrillation; Cardiology Service, Hospital; Clopidogrel; Female; Hospital Departments; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Israel; Male; Medication Therapy Management; Middle Aged; Patient Discharge; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Practice Patterns, Physicians'; Retrospective Studies; Secondary Prevention; Ticlopidine | 2015 |
Bifrontal headache · blurred vision · vomiting · Dx?
Topics: Aspirin; Clopidogrel; Diagnosis, Differential; Drug Therapy, Combination; Female; Headache; Humans; Magnetic Resonance Imaging; Middle Aged; Platelet Aggregation Inhibitors; Posterior Leukoencephalopathy Syndrome; Ticlopidine; Tomography, X-Ray Computed; Vision Disorders; Vomiting | 2015 |
Ventriculostomy-Related Hemorrhage After Treatment of Acutely Ruptured Aneurysms: The Influence of Anticoagulation and Antiplatelet Treatment.
Topics: Acute Disease; Adult; Aged; Aneurysm, Ruptured; Anticoagulants; Aspirin; Cerebral Hemorrhage; Clopidogrel; Endovascular Procedures; Female; Heparin, Low-Molecular-Weight; Humans; Hydrocephalus; Intracranial Aneurysm; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Thromboembolism; Ticlopidine; Tirofiban; Tyrosine; Ventriculostomy | 2015 |
Dual antiplatelet therapy for TIA reduces subsequent disability: A CHANCE to improve outcomes?
Topics: Aspirin; Female; Humans; Ischemic Attack, Transient; Male; Outcome Assessment, Health Care; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2015 |
Clopidogrel response variability is associated with endothelial dysfunction in coronary artery disease patients receiving dual antiplatelet therapy.
Topics: Activation, Metabolic; Aged; Aspirin; Brachial Artery; Clopidogrel; Coronary Disease; Cytochrome P-450 CYP2C19; Diabetes Mellitus; Drug Synergism; Drug Therapy, Combination; Endothelium, Vascular; Female; Genotype; Humans; Hyperlipidemias; Male; Middle Aged; Obesity; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Function Tests; Postoperative Complications; Prospective Studies; Purinergic P2Y Receptor Antagonists; Risk Factors; Smoking; Stents; Thrombophilia; Ticlopidine; Vasodilation | 2015 |
Long-term Outcomes of Medical Therapy Versus Coronary Revascularisation in Patients with Intermediate Stenoses Guided by Pressure Wire.
Topics: Adult; Aged; Aspirin; Clopidogrel; Coronary Stenosis; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Retrospective Studies; Ticlopidine; Treatment Outcome | 2015 |
Acute spinal cord compression: a rare complication of dual antiplatelet therapy.
Topics: Acute Disease; Aged; Aspirin; Clopidogrel; Drug Therapy, Combination; Fatal Outcome; Female; Hematoma; Humans; Platelet Aggregation Inhibitors; Pressure Ulcer; Sepsis; Spinal Cord Compression; Ticlopidine | 2015 |
Antithrombotic drugs and subarachnoid haemorrhage risk. A nationwide case-control study in Denmark.
Topics: Aged; Aspirin; Case-Control Studies; Clopidogrel; Denmark; Drug Therapy, Combination; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Neurosurgical Procedures; Postoperative Complications; Risk; Subarachnoid Hemorrhage; Thrombosis; Ticlopidine; Vitamin K | 2015 |
Clopidogrel Enhances Mesenchymal Stem Cell Proliferation Following Periodontitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Movement; Cell Proliferation; Clopidogrel; Gingiva; Male; Mesenchymal Stem Cells; Osteoblasts; Periodontitis; Purinergic P2Y Receptor Antagonists; Rats; Rats, Sprague-Dawley; Ticlopidine | 2015 |
Simultaneous quantitation of acetylsalicylic acid and clopidogrel along with their metabolites in human plasma using liquid chromatography tandem mass spectrometry.
Topics: Aspirin; Chromatography, Liquid; Clopidogrel; Drug Monitoring; Drug Stability; Humans; Limit of Detection; Reproducibility of Results; Tandem Mass Spectrometry; Ticlopidine | 2016 |
Antithrombotic and Antiplatelet Therapy in Patients Requiring Oral Anticoagulation After Percutaneous Coronary Intervention.
Topics: Anticoagulants; Aspirin; Humans; Myocardial Ischemia; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticlopidine | 2015 |
Soluble CD40 Ligand in Aspirin-Treated Patients Undergoing Cardiac Catheterization.
Topics: Aspirin; Cardiac Catheterization; Cardiovascular Diseases; CD40 Ligand; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine | 2015 |
Platelet reactivity in MitraClip patients.
Topics: Aspirin; Clopidogrel; Cohort Studies; Heart Valve Prosthesis Implantation; Hemorrhage; Ischemia; Mitral Valve Insufficiency; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine | 2016 |
Triple Therapy...Can We Replace More With Better?
Topics: Anticoagulants; Aspirin; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2015 |
Obesity and antiplatelet effects of acetylsalicylic acid and clopidogrel in patients with stable angina pectoris after percutaneous coronary intervention.
Topics: Aged; Angina, Stable; Aspirin; Clopidogrel; Female; Humans; Male; Middle Aged; Obesity; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2015 |
Management of Antiplatelet Therapy After Coronary Artery Bypass Grafting in the Setting of Acute Coronary Syndrome.
Topics: Acute Coronary Syndrome; Aspirin; Coronary Artery Bypass; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2015 |
Association of CYP2C19, CYP3A5 and GPIIb/IIIa gene polymorphisms with Aspirin and Clopidogrel Resistance in a cohort of Indian patients with Coronary Artery Disease.
Topics: Aged; Alleles; Antigens, Human Platelet; Aspirin; Case-Control Studies; Clopidogrel; Cohort Studies; Comorbidity; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Drug Resistance; Female; Genotype; Humans; India; Integrin beta3; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Risk Factors; Ticlopidine; Treatment Outcome | 2015 |
Antiplatelet therapy in Takotsubo cardiomyopathy: does it improve cardiovascular outcomes during index event?
Topics: Aged; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Heart Failure; Hospital Mortality; Humans; Length of Stay; Logistic Models; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Severity of Illness Index; Stroke; Takotsubo Cardiomyopathy; Ticlopidine; Treatment Outcome | 2016 |
Independent Predictors of Major Adverse Events following Coronary Stenting over 28 Months of Follow-Up.
Topics: Acute Coronary Syndrome; Adult; Aged; Aspirin; Case-Control Studies; Clopidogrel; Coronary Angiography; Drug-Eluting Stents; Echocardiography; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Plasminogen Activator Inhibitor 1; Postoperative Complications; Prospective Studies; Risk Factors; Thrombosis; Ticlopidine; Treatment Outcome; von Willebrand Factor | 2015 |
Dual Antiplatelet Therapy Prior to Expedited Carotid Surgery Reduces Recurrent Events Prior to Surgery without Significantly Increasing Peri-operative Bleeding Complications.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Carotid Stenosis; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Endarterectomy, Carotid; England; Female; Humans; Ischemic Attack, Transient; Male; Medical Audit; Middle Aged; Odds Ratio; Patient Transfer; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Prevalence; Prospective Studies; Recurrence; Risk Assessment; Risk Factors; Severity of Illness Index; Ticlopidine; Time Factors; Time-to-Treatment; Treatment Outcome | 2015 |
Platelet reactivity and hemorrhage risk in neurointerventional procedures under dual antiplatelet therapy.
Topics: Aged; Aspirin; Carotid Stenosis; Clopidogrel; Drug Therapy, Combination; Embolization, Therapeutic; Female; Hemorrhage; Humans; Intracranial Aneurysm; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Risk; ROC Curve; Stents; Ticlopidine; Treatment Outcome | 2016 |
Failure of the Platelet Function Assay (PFA)-100 to detect antiplatelet agents.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Platelet Disorders; Brain Injuries; Clopidogrel; False Negative Reactions; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Function Tests; Retrospective Studies; Stroke; Ticlopidine | 2015 |
Impact of residual platelet reactivity under clopidogrel treatment for lesions and the clinical outcome after drug-eluting stent implantation in patients with hemodialysis.
Topics: Aged; Angina, Stable; Aspirin; Blood Platelets; Case-Control Studies; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Renal Dialysis; Thrombosis; Ticlopidine; Tomography, Optical Coherence | 2016 |
Is Acute Carotid Artery Stent Thrombosis an Avoidable Complication?
Topics: Aged; Aged, 80 and over; Aspirin; Carotid Artery Thrombosis; Cerebral Angiography; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2015 |
Aspirin plus ticlopidine prevented experimental endocarditis due to Enterococcus faecalis and Streptococcus gallolyticus.
Topics: Animals; Aspirin; Disease Models, Animal; Endocarditis, Bacterial; Enterococcus faecalis; Female; Gram-Positive Bacterial Infections; Platelet Aggregation Inhibitors; Rats, Wistar; Streptococcus; Ticlopidine; Treatment Outcome | 2015 |
Duration of Triple Therapy in Patients Requiring Oral Anticoagulation After Drug-Eluting Stent Implantation.
Topics: Aspirin; Drug-Eluting Stents; Female; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine | 2015 |
Reply: Duration of Triple Therapy in Patients Requiring Oral Anticoagulation After Drug-Eluting Stent Implantation.
Topics: Aspirin; Drug-Eluting Stents; Female; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine | 2015 |
Ticagrelor shift from PLATO to PEGASUS: Vanished mortality benefit, excess cancer deaths, massive discontinuations, and overshooting target events.
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Clopidogrel; Follow-Up Studies; Hemorrhage; Humans; Mortality; Neoplasms; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Randomized Controlled Trials as Topic; Sepsis; Ticagrelor; Ticlopidine | 2015 |
Optical coherence tomography analysis of the stent strut and prediction of resolved strut malapposition at 3 months after 2nd-generation drug-eluting stent implantation.
Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Vessels; Drug-Eluting Stents; Everolimus; Female; Humans; Japan; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prosthesis Design; Sirolimus; Thrombosis; Ticlopidine; Tomography, Optical Coherence | 2016 |
Accumetrics-based clopidogrel dosing in endovascular neurosurgery.
Topics: Aged; Aspirin; Cerebral Hemorrhage; Clopidogrel; Drug Therapy, Combination; Endovascular Procedures; Female; Humans; Male; Middle Aged; Neurosurgical Procedures; Platelet Aggregation Inhibitors; Postoperative Complications; Retrospective Studies; Thromboembolism; Ticlopidine; Treatment Outcome | 2015 |
Age- and Gender-related Disparities in Primary Percutaneous Coronary Interventions for Acute ST-segment elevation Myocardial Infarction.
Topics: Age Factors; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Female; Geriatrics; Hospitals; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Sex Characteristics; Switzerland; Ticlopidine; Treatment Outcome | 2015 |
Low platelet activity predicts 30 days mortality in patients undergoing heart surgery.
Topics: Adenosine Diphosphate; Aged; Aortic Valve; Arachidonic Acid; Area Under Curve; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Erythrocyte Transfusion; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prognosis; Retrospective Studies; Risk Factors; Survival Analysis; Thrombosis; Ticlopidine; Treatment Outcome | 2016 |
Interest of Antiplatelet Drug Testing after an Acute Ischemic Stroke.
Topics: Aged; Aspirin; Clopidogrel; Drug Resistance; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Function Tests; Stroke; Ticlopidine; United States | 2015 |
Underutilisation of Guideline-based Therapy Primary Prevention among Patients Presenting with AF-related Ischaemic Stroke.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Brain Ischemia; Clopidogrel; Dabigatran; Dipyridamole; Female; Guideline Adherence; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Primary Prevention; Pyrazoles; Pyridones; Rivaroxaban; Stroke; Ticlopidine; Warfarin | 2015 |
Effects of prasugrel pretreatment on angiographic myocardial perfusion parameters in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention.
Topics: Aged; Aspirin; Case-Control Studies; Clopidogrel; Coronary Angiography; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Perfusion Imaging; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Premedication; Ticlopidine; Treatment Outcome | 2015 |
Dual antiplatelet therapy use by Canadian cardiac surgeons.
Topics: Adenosine; Aspirin; Canada; Clopidogrel; Coronary Artery Bypass; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Practice Patterns, Physicians'; Ticagrelor; Ticlopidine | 2015 |
Platelet function recovery following exposure to triple anti-platelet inhibitors using an in vitro transfusion model.
Topics: Apoptosis Regulatory Proteins; Arachidonic Acid; Aspirin; Blood Platelets; Blood Transfusion; Clopidogrel; Flow Cytometry; Hemorrhage; Humans; Lactones; P-Selectin; Peptide Fragments; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Transfusion; Purinergic P2Y Receptor Antagonists; Pyridines; Receptors, Proteinase-Activated; Receptors, Purinergic P2Y12; Ticlopidine | 2015 |
Low-dose adjunctive cilostazol in patients with complex lesions undergoing percutaneous coronary intervention.
Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Disease; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Safety; Tetrazoles; Ticlopidine; Treatment Outcome | 2016 |
Platelet Larger Cell Ratio and High-on Treatment Platelet Reactivity During Dual Antiplatelet Therapy.
Topics: Adenosine; Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticagrelor; Ticlopidine | 2015 |
Aspirin and clopidogrel during robotic partial nephrectomy, is it safe?
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Clopidogrel; Feasibility Studies; Female; Humans; Kidney Neoplasms; Male; Middle Aged; Nephrectomy; Patient Selection; Perioperative Period; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Robotic Surgical Procedures; Ticlopidine; Withholding Treatment | 2015 |
An Infected Aneurysm of the Vertebral Artery Treated with a Stent-graft: A Case Report.
Topics: Aged; Aneurysm, Infected; Angiography; Aspirin; Clopidogrel; Drug Combinations; Humans; Male; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Tomography, X-Ray Computed; Vertebral Artery | 2015 |
Predicting Bleeding Risk by Platelet Function Testing in Patients Undergoing Heart Surgery.
Topics: Adult; Aged; Aged, 80 and over; Area Under Curve; Aspirin; Blood Loss, Surgical; Cardiopulmonary Bypass; Clopidogrel; Coronary Artery Bypass; Coronary Artery Bypass, Off-Pump; Drug Administration Schedule; Drug Therapy, Combination; Erythrocyte Transfusion; Female; Heart Valve Prosthesis Implantation; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Retrospective Studies; Risk Assessment; Risk Factors; ROC Curve; Ticlopidine; Time Factors; Treatment Outcome; Young Adult | 2015 |
Is Extended Duration of Dual Antiplatelet Therapy After Carotid Stenting Beneficial?
Topics: Aged; Aspirin; Carotid Arteries; Carotid Stenosis; Clopidogrel; Female; Follow-Up Studies; Humans; Male; Platelet Aggregation Inhibitors; Proportional Hazards Models; Retrospective Studies; Stents; Stroke; Ticlopidine | 2015 |
Severe Cutaneous Bleeding: An Unusual Complication of Dual Antiplatelet Therapy.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Ecchymosis; Female; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2015 |
A New Protocol for Anticoagulation With Tirofiban During Flow Diversion.
Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Clinical Protocols; Clopidogrel; Embolization, Therapeutic; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Intracranial Aneurysm; Intracranial Hemorrhages; Intraoperative Care; Male; Middle Aged; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Tirofiban; Tyrosine | 2016 |
Duration of dual antiplatelet therapy after coronary stenting.
Topics: Aspirin; Coronary Artery Disease; Drug Therapy, Combination; Graft Occlusion, Vascular; Humans; Platelet Aggregation Inhibitors; Postoperative Care; Stents; Ticlopidine; Time Factors | 2016 |
Influence of Diabetes Mellitus and Cigarette Smoking on Variability of the Clopidogrel-Induced Antiplatelet Effect and Efficacy of Active Management of the Target P2Y12 Reaction Unit Range in Patients Undergoing Neurointerventional Procedures.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aspirin; Carotid Stenosis; Cilostazol; Clopidogrel; Diabetes Mellitus; Drug Resistance; Drug Therapy, Combination; Embolization, Therapeutic; Female; Humans; Intracranial Aneurysm; Male; Middle Aged; Neurosurgical Procedures; Platelet Aggregation; Platelet Aggregation Inhibitors; Premedication; Prospective Studies; Purinergic P2Y Receptor Antagonists; Smoking; Stents; Tetrazoles; Ticlopidine | 2016 |
Successful Prasugrel Therapy for Recurrent Left Main Stent Thrombosis in a Clopidogrel Hyporesponder.
Topics: Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Thrombosis; Drug Resistance; Drug Substitution; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Prosthesis Design; Recurrence; Ticlopidine; Time Factors; Treatment Outcome | 2015 |
Preprocedural Dual Antiplatelet Therapy for Percutaneous Coronary Intervention in Japanese Current Practice.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Drug Therapy, Combination; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticlopidine | 2015 |
Advanced age and high-residual platelet reactivity in patients receiving dual antiplatelet therapy with clopidogrel or ticagrelor.
Topics: Adenosine; Adenosine Diphosphate; Age Factors; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Clopidogrel; Cohort Studies; Female; Humans; Male; Middle Aged; Odds Ratio; Patient Discharge; Percutaneous Coronary Intervention; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prevalence; Thrombosis; Ticagrelor; Ticlopidine; Time Factors | 2016 |
Safety of prasugrel in real-world patients with ST-segment elevation myocardial infarction: 1-year results from a prospective observational study (Bleeding and Myocardial Infarction Study).
Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Patient Selection; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Prospective Studies; Registries; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome | 2016 |
Impact of atorvastatin or rosuvastatin co-administration on platelet reactivity in patients treated with dual antiplatelet therapy.
Topics: Adenosine; Aged; Aspirin; Atorvastatin; Chi-Square Distribution; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Female; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polypharmacy; Risk Assessment; Risk Factors; Rosuvastatin Calcium; Ticagrelor; Ticlopidine; Treatment Outcome | 2015 |
Comparison of antiplatelet regimens in secondary stroke prevention: a nationwide cohort study.
Topics: Aged; Aged, 80 and over; Aspirin; Brain Ischemia; Cerebral Hemorrhage; Clopidogrel; Cohort Studies; Denmark; Dipyridamole; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Platelet Aggregation Inhibitors; Recurrence; Registries; Secondary Prevention; Stroke; Ticlopidine | 2015 |
Endobronchial Ultrasound-guided Transbronchial Needle Aspiration while Receiving Aspirin and Clopidogrel: Is It Always Safe?
Topics: Aspirin; Clopidogrel; Contraindications; Echocardiography, Doppler, Color; Endoscopic Ultrasound-Guided Fine Needle Aspiration; Female; Hemorrhage; Humans; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine | 2015 |
Is platelet transfusion the solution to reverse platelet inhibition in patients on triple antiplatelet therapy?
Topics: Aspirin; Blood Platelets; Drug Therapy, Combination; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Transfusion; Ticlopidine | 2015 |
J Curve and Cuff Artefact, and Diagnostic Inertia in Resistant Hypertension.
Topics: Aspirin; Blood Pressure; Female; Humans; Hypertension; Male; Secondary Prevention; Stroke, Lacunar; Ticlopidine | 2016 |
Antiplatelet effects of clopidogrel and aspirin after interventional patent foramen ovale/ atrium septum defect closure.
Topics: Adult; Aged; Aspirin; Blood Platelets; Cardiac Surgical Procedures; Clopidogrel; Comorbidity; Female; Follow-Up Studies; Foramen Ovale, Patent; Hemorrhage; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Postoperative Care; Preoperative Care; Risk Factors; Ticlopidine; Treatment Outcome | 2016 |
Duration of Triple Therapy: A Clinical Question Yet to Be Answered.
Topics: Aspirin; Drug-Eluting Stents; Female; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine | 2015 |
Reply: Duration of Triple Therapy: A Clinical Question Yet to Be Answered.
Topics: Aspirin; Drug-Eluting Stents; Female; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine | 2015 |
It Is Not Mandatory to Use Triple Rather Than Dual Anti-Platelet Therapy After a Percutaneous Coronary Intervention With a Second-Generation Drug-Eluting Stent.
Topics: Adult; Aged; Aspirin; Cilostazol; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Everolimus; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Care; Postoperative Complications; Registries; Sirolimus; Tetrazoles; Thrombosis; Ticlopidine; Treatment Outcome | 2015 |
Relationship between Inflammation and Aspirin and Clopidogrel Antiplatelet Responses in Acute Ischemic Stroke.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Biomarkers; Brain Ischemia; CD40 Ligand; Clopidogrel; Female; Humans; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-6; Male; Matrix Metalloproteinase 9; Middle Aged; P-Selectin; Platelet Aggregation Inhibitors; Secondary Prevention; Stroke; Ticlopidine | 2016 |
CYP2C19 and CES1 polymorphisms and efficacy of clopidogrel and aspirin dual antiplatelet therapy in patients with symptomatic intracranial atherosclerotic disease.
Topics: Aged; Aspirin; Carboxylic Ester Hydrolases; Clopidogrel; Cytochrome P-450 CYP2C19; Female; Gene Frequency; Genotyping Techniques; Heterozygote; Humans; Intracranial Arteriosclerosis; Ischemic Attack, Transient; Kaplan-Meier Estimate; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Prospective Studies; Stroke; Ticlopidine | 2016 |
Insufficient platelet inhibition and thromboembolic complications in patients with intracranial aneurysms after stent placement.
Topics: Adult; Aged; Aspirin; Clopidogrel; Drug Resistance; Female; Humans; Intracranial Aneurysm; Male; Middle Aged; Neurosurgical Procedures; Platelet Aggregation Inhibitors; Postoperative Complications; Prospective Studies; Stents; Thromboembolism; Ticlopidine | 2016 |
Antiplatelet therapy: Clopidogrel plus aspirin reduces migrane attacks after ASD closure.
Topics: Aspirin; Cardiac Catheterization; Cardiac Surgical Procedures; Female; Headache Disorders, Secondary; Heart Septal Defects, Atrial; Humans; Male; Migraine Disorders; Platelet Aggregation Inhibitors; Ticlopidine | 2016 |
Stent thrombosis after primary percutaneous coronary intervention in comatose survivors of out-of-hospital cardiac arrest: Are the new P2Y12 inhibitors really more effective than clopidogrel?
Topics: Adenosine; Aspirin; Clopidogrel; Coma; Coronary Angiography; Coronary Thrombosis; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Out-of-Hospital Cardiac Arrest; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Retrospective Studies; Risk Factors; Stents; Ticagrelor; Ticlopidine; Treatment Outcome | 2016 |
Determinants of pre-hospital pharmacological intervention and its association with outcome in acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Aged; Analgesics, Opioid; Anticoagulants; Aspirin; Clopidogrel; Electrocardiography; Emergency Medical Services; Female; Humans; Male; Morphine; Myocardial Infarction; Nitroglycerin; Oxygen; Platelet Aggregation Inhibitors; Sweden; Ticlopidine; Treatment Outcome; Vasodilator Agents | 2015 |
Low On-Treatment Platelet Reactivity Predicts Long-Term Risk of Bleeding After Elective PCI.
Topics: Aged; Aspirin; Clopidogrel; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Activation; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Predictive Value of Tests; Prospective Studies; Risk; Ticlopidine; Time Factors | 2015 |
[Stent-Assisted Coil Embolization of a Dissecting Aneurysm of the Posterior Cerebral Artery: A Case Report].
Topics: Aortic Dissection; Aspirin; Clopidogrel; Embolization, Therapeutic; Female; Fibrinolytic Agents; Humans; Intracranial Aneurysm; Middle Aged; Posterior Cerebral Artery; Stents; Ticlopidine | 2015 |
Aspirin in the prevention of cardiovascular events in patients with diabetes.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Diabetes Complications; Diabetes Mellitus; Drug Administration Schedule; Half-Life; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2016 |
Cochlear Implantation in the Setting of Perioperative Anticoagulation and Antiplatelet Therapy.
Topics: Aged; Anticoagulants; Aspirin; Blood Loss, Surgical; Clopidogrel; Cochlear Implantation; Female; Hemorrhage; Humans; Male; Platelet Aggregation Inhibitors; Postoperative Complications; Ticlopidine; Treatment Outcome; Warfarin | 2016 |
Successful Management of Recurrent Colon Ulcer in Hemodialysis Patient after Conversion to Peritoneal Dialysis.
Topics: Aspirin; Colon; Colonic Diseases; Colonoscopy; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Kidney Failure, Chronic; Male; Middle Aged; Peritoneal Dialysis; Recurrence; Ticlopidine; Ulcer | 2015 |
Platelet reactivity in patients undergoing transcatheter aortic valve implantation.
Topics: Aged; Aged, 80 and over; Aortic Valve Stenosis; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Humans; Male; Platelet Activation; Platelet Aggregation Inhibitors; Thromboembolism; Ticlopidine; Transcatheter Aortic Valve Replacement; Warfarin | 2016 |
Dual platelet inhibition in cases of severe retrobulbar hemorrhage following retrobulbar and peribulbar anesthesia.
Topics: Aged; Anesthesia, Local; Anticoagulants; Arterial Occlusive Diseases; Aspirin; Cardiac Surgical Procedures; Cardiovascular Diseases; Clopidogrel; Drug Combinations; Female; Humans; Lens Implantation, Intraocular; Male; Phacoemulsification; Platelet Aggregation Inhibitors; Retrobulbar Hemorrhage; Retrospective Studies; Risk Factors; Ticlopidine; Warfarin | 2015 |
[Impact of preoperative dual antiplatelet therapy on perioperative bleeding in patients undergoing off-pump coronary artery bypass grafting].
Topics: Aspirin; Blood Transfusion; Clopidogrel; Coronary Artery Bypass, Off-Pump; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2015 |
Do Not Use Novel Antiplatelet Agents in Patients on Oral Anticoagulants After Stenting.
Topics: Acute Coronary Syndrome; Administration, Oral; Anticoagulants; Aspirin; Drug Therapy, Combination; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2015 |
Is There an Ideal Level of Platelet P2Y12-Receptor Inhibition in Patients Undergoing Percutaneous Coronary Intervention?: "Window" Analysis From the ADAPT-DES Study (Assessment of Dual AntiPlatelet Therapy With Drug-Eluting Stents).
Topics: Aged; Aspirin; Blood Platelets; Chi-Square Distribution; Clopidogrel; Coronary Disease; Coronary Thrombosis; Drug Resistance; Drug Therapy, Combination; Drug-Eluting Stents; Female; Germany; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Prosthesis Design; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Registries; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome; United States | 2015 |
Factors influencing platelet reactivity in patients undergoing coronary artery bypass surgery.
Topics: Acute Coronary Syndrome; Adenosine; Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Bypass; Drug Therapy, Combination; Female; Flow Cytometry; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Purinergic P2Y Receptor Antagonists; Ticagrelor; Ticlopidine; Time Factors; Treatment Outcome | 2016 |
Clopidogrel Versus Aspirin as an Antiplatelet Monotherapy After 12-Month Dual-Antiplatelet Therapy in the Era of Drug-Eluting Stents.
Topics: Aged; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug-Eluting Stents; Female; Humans; Incidence; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Proportional Hazards Models; Recurrence; Registries; Republic of Korea; Survival Rate; Ticlopidine; Time Factors; Treatment Outcome | 2016 |
Risk of early recurrent stroke in symptomatic carotid stenosis after best medical therapy and before endarterectomy.
Topics: Aged; Aged, 80 and over; Aspirin; Carotid Arteries; Carotid Stenosis; Clopidogrel; Endarterectomy, Carotid; Fibrinolytic Agents; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemic Attack, Transient; Middle Aged; New Zealand; Platelet Aggregation Inhibitors; Prospective Studies; Recurrence; Risk; Stroke; Ticlopidine; Time Factors | 2016 |
Commentary: Cilostazol and Carotid Stenting: A Merry Marriage?
Topics: Aspirin; Drug Therapy, Combination; Humans; Marriage; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Treatment Outcome | 2016 |
High on-aspirin platelet reactivity predicts cardiac death in acute coronary syndrome patients undergoing PCI.
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Clopidogrel; Death; Drug-Eluting Stents; Female; Humans; Italy; Kaplan-Meier Estimate; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine | 2016 |
Assessment of platelet-derived thrombogenicity with the total thrombus-formation analysis system in coronary artery disease patients receiving antiplatelet therapy.
Topics: Aged; Area Under Curve; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cross-Sectional Studies; Cytochrome P-450 CYP2C19; Electrocardiography; Female; Genotype; Humans; Male; Middle Aged; Phenotype; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Genetic; Thrombosis; Ticlopidine | 2016 |
Late Major Hemoptysis After Lung Volume Reduction With Coils Induced by Dual Antiaggregation Therapy.
Topics: Aspirin; Clopidogrel; Hemoptysis; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Pneumonectomy; Postoperative Complications; Pulmonary Emphysema; Severity of Illness Index; Ticlopidine; Time Factors | 2016 |
Spontaneous coronary artery dissection in the presence of myocardial bridge causing myocardial infarction: an insight into mechanism.
Topics: Adult; Aspirin; Atorvastatin; Clopidogrel; Coronary Angiography; Coronary Vessel Anomalies; Female; Humans; Myocardial Bridging; Myocardial Infarction; Perindopril; Ticlopidine; Treatment Outcome; Vascular Diseases | 2016 |
Influence of platelet reactivity on BARC classification in East Asian patients undergoing percutaneous coronary intervention. Results of the ACCEL-BLEED study.
Topics: Aged; Asia, Eastern; Asian People; Aspirin; Cell Adhesion Molecules; Clopidogrel; Cytochrome P-450 CYP2C19; Female; Hemorrhage; Humans; Male; Microfilament Proteins; Middle Aged; Percutaneous Coronary Intervention; Phosphoproteins; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Single Nucleotide; Prospective Studies; Purinergic P2Y Receptor Antagonists; Ticlopidine; Time Factors | 2016 |
Treatment with Clopidogrel Prior to Acute Non-Cardioembolic Ischemic Stroke Attenuates Stroke Severity.
Topics: Aged; Aged, 80 and over; Aspirin; Brain Ischemia; Chi-Square Distribution; Clopidogrel; Disability Evaluation; Female; Hospital Mortality; Humans; Logistic Models; Male; Odds Ratio; Patient Admission; Patient Discharge; Platelet Aggregation Inhibitors; Prospective Studies; Protective Factors; Recovery of Function; Risk Factors; Severity of Illness Index; Stroke; Ticlopidine; Time Factors; Treatment Outcome | 2016 |
Clopidogrel Use as Single Antiplatelet Therapy in Outpatients with Stable Coronary Artery Disease: Prevalence, Correlates and Association with Prognosis (from the CORONOR Study).
Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Endovascular Procedures; Female; France; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Outcome and Process Assessment, Health Care; Outpatients; Platelet Aggregation Inhibitors; Prevalence; Prognosis; Registries; Stroke; Ticlopidine | 2016 |
Triple vs Dual Antithrombotic Therapy in Patients with Atrial Fibrillation and Coronary Artery Disease.
Topics: Administration, Oral; Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Comorbidity; Coronary Artery Disease; Drug Therapy, Combination; Female; Fibrinolytic Agents; Hospitalization; Humans; Male; Markov Chains; Monte Carlo Method; Myocardial Infarction; Outcome and Process Assessment, Health Care; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proportional Hazards Models; Pyridines; Registries; Stroke; Ticlopidine; Warfarin | 2016 |
Impact of Triple Therapy in Elderly Patients with Atrial Fibrillation Undergoing Percutaneous Coronary Intervention.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Female; Humans; Male; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prospective Studies; Risk Factors; Ticlopidine | 2016 |
Continuation and adherence rates on initially-prescribed intensive secondary prevention therapy after Rapid Access Stroke Prevention (RASP) service assessment.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Aspirin; Brain Ischemia; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Female; Humans; Incidence; Male; Medication Adherence; Middle Aged; Recurrence; Secondary Prevention; Stroke; Ticlopidine; Treatment Outcome; Warfarin; Young Adult | 2016 |
Usefulness of Intravascular Ultrasound for Predicting Risk of Intraprocedural Stent Thrombosis.
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Humans; Japan; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Predictive Value of Tests; Retrospective Studies; Risk Assessment; Risk Factors; Sensitivity and Specificity; Stents; Thrombosis; Ticlopidine; Ultrasonography, Interventional | 2016 |
The Importance of the Mean Platelet Aggregation Degree in Long-term Dual Antiplatelet Therapy Following Drug-Eluting Stent Implantation.
Topics: Aged; Aspirin; Chi-Square Distribution; Clopidogrel; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Proportional Hazards Models; Registries; Retrospective Studies; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome | 2016 |
Likelihood ratio meta-analysis: New motivation and approach for an old method.
Topics: Aspirin; Bayes Theorem; Clopidogrel; Data Interpretation, Statistical; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Likelihood Functions; Meta-Analysis as Topic; Models, Statistical; Myocardial Infarction; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stroke; Ticlopidine; Treatment Outcome | 2016 |
Prevalence and risk factors of clopidogrel non-response among Saudi patients undergoing coronary angiography.
Topics: Adult; Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Cross-Sectional Studies; Female; Humans; In Vitro Techniques; Logistic Models; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Odds Ratio; Platelet Aggregation Inhibitors; Prevalence; Risk Factors; Saudi Arabia; Ticlopidine; Treatment Failure | 2016 |
Cost effectiveness of left atrial appendage closure with the Watchman device for atrial fibrillation patients with absolute contraindications to warfarin.
Topics: Anticoagulants; Aspirin; Atrial Appendage; Atrial Fibrillation; Cardiac Surgical Procedures; Clopidogrel; Contraindications; Cost-Benefit Analysis; Germany; Humans; Markov Chains; Models, Theoretical; Pyrazoles; Pyridones; Quality of Life; Quality-Adjusted Life Years; Stroke; Ticlopidine; Time Factors; Treatment Outcome; Warfarin | 2016 |
The Antiplatelet Effect of Clopidogrel Decreases With Patient Age.
Topics: Adenosine Diphosphate; Age Factors; Aged; Aspirin; Clopidogrel; Drug Therapy, Combination; Flow Cytometry; Humans; P-Selectin; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine; Treatment Outcome | 2016 |
Prolonged dual antiplatelet therapy: a potential mitigator of the adverse effects of local haemodynamic shear stress in high-risk coronary regions?
Topics: Aspirin; Drug Therapy, Combination; Hemodynamics; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2016 |
The Impact of CYP2C19 Loss-of-Function Polymorphisms, Clinical, and Demographic Variables on Platelet Response to Clopidogrel Evaluated Using Impedance Aggregometry.
Topics: Acute Coronary Syndrome; Aspirin; Blood Platelets; Cardiography, Impedance; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Resistance; Drug Synergism; Europe, Eastern; Genotype; Humans; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Prevalence; Stroke; Ticlopidine | 2017 |
Antiplatelet Therapy in TAVI: Current Clinical Practice and Recommendations.
Topics: Administration, Oral; Anticoagulants; Aortic Valve Stenosis; Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Transcatheter Aortic Valve Replacement | 2016 |
Comparison of Three Tests to Distinguish Platelet Reactivity in Patients with Renal Impairment during Dual Antiplatelet Therapy.
Topics: Aged; Aspirin; Clopidogrel; Cross-Sectional Studies; Female; Glomerular Filtration Rate; Hemorrhage; Humans; Kidney Diseases; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Thrombosis; Ticlopidine | 2016 |
[Impact of novel P2Y12 receptor inhibitors on platelet reactivity in acute coronary syndrome patients undergoing percutaneous coronary intervention].
Topics: Acute Coronary Syndrome; Adenosine; Aged; Aspirin; Blood Platelets; Clopidogrel; Female; Humans; Male; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Prospective Studies; Ticagrelor; Ticlopidine | 2016 |
Antiplatelet Therapy of Cilostazol or Sarpogrelate with Aspirin and Clopidogrel after Percutaneous Coronary Intervention: A Retrospective Cohort Study Using the Korean National Health Insurance Claim Database.
Topics: Aspirin; Cilostazol; Clopidogrel; Drug-Related Side Effects and Adverse Reactions; Hemorrhage; Humans; Insurance, Health; Korea; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Succinates; Tetrazoles; Ticlopidine; Treatment Outcome | 2016 |
Dual antiplatelet therapy reduces stroke but increases bleeding at the time of carotid endarterectomy.
Topics: Aged; Aspirin; Asymptomatic Diseases; Carotid Artery Diseases; Chi-Square Distribution; Clopidogrel; Comorbidity; Drug Administration Schedule; Drug Therapy, Combination; Endarterectomy, Carotid; Female; Hemorrhage; Hospital Mortality; Humans; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Platelet Aggregation Inhibitors; Propensity Score; Protective Factors; Registries; Reoperation; Retrospective Studies; Risk Assessment; Risk Factors; Stroke; Ticlopidine; Time Factors; Treatment Outcome; United States | 2016 |
Impact of diabetes on immature platelets fraction and its relationship with platelet reactivity in patients receiving dual antiplatelet therapy.
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Clopidogrel; Diabetes Mellitus; Drug Therapy, Combination; Humans; Percutaneous Coronary Intervention; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticagrelor; Ticlopidine | 2016 |
Association of PEAR1 genetic variants with platelet reactivity in response to dual antiplatelet therapy with aspirin and clopidogrel in the Chinese patient population after percutaneous coronary intervention.
Topics: Aged; Asian People; Aspirin; Blood Platelets; China; Clopidogrel; Coronary Disease; Female; Haplotypes; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Receptors, Cell Surface; Ticlopidine | 2016 |
Dental extraction without stopping single or dual antiplatelet therapy: results of a retrospective cohort study.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Retrospective Studies; Ticlopidine; Tooth Extraction; Young Adult | 2016 |
Bleeding after tooth extraction in patients taking aspirin and clopidogrel (Plavix®) compared with healthy controls.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Oral Hemorrhage; Platelet Aggregation Inhibitors; Ticlopidine; Tooth Extraction | 2016 |
Impact of preoperative dual antiplatelet therapy on bleeding complications in patients with acute coronary syndromes who undergo urgent coronary artery bypass grafting.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Blood Transfusion; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Emergencies; Female; Humans; Japan; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Preoperative Care; Pyridines; Retrospective Studies; Ticlopidine; Time Factors; Treatment Outcome | 2017 |
Save the Unlucky Unrevascularized Acute Coronary Syndrome Patient.
Topics: Acute Coronary Syndrome; Aspirin; Electrocardiography; Female; Humans; Male; Myocardial Infarction; Prasugrel Hydrochloride; Risk Assessment; Ticlopidine | 2016 |
Effects of Arnica comp.-Heel® on reducing cardiovascular events in patients with stable coronary disease.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Middle Aged; Plants, Medicinal; Plaque, Atherosclerotic; Platelet Aggregation Inhibitors; Retrospective Studies; Secondary Prevention; Tablets; Ticlopidine; Treatment Outcome | 2016 |
A COGENT Argument for Gastrointestinal Protection With Low-Dose Aspirin.
Topics: Aspirin; Female; Humans; Male; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine | 2016 |
Clinical Features and Outcomes of Diffuse Alveolar Hemorrhage During Antithrombotic Therapy: A Retrospective Cohort Study.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cilostazol; Clopidogrel; Connective Tissue Diseases; Female; Fibrinolytic Agents; Heart Failure; Hemorrhage; Humans; Infections; Lung Diseases; Male; Middle Aged; Neoplasms; Pneumonia; Pulmonary Alveoli; Retrospective Studies; Survival Rate; Tetrazoles; Ticlopidine; Vasculitis; Warfarin | 2016 |
Dual Antiplatelet Therapy Beyond 1 Year Postinfarction: The Time Has Come and We're Beginning to Know Who Will Benefit.
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Myocardial Infarction; Patient Selection; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Secondary Prevention; Ticagrelor; Ticlopidine; Time Factors | 2016 |
Proton pump inhibitors and other disease-based factors in the recurrence of adverse cardiovascular events following percutaneous coronary angiography: A long-term cohort.
Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Drug Combinations; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Recurrence; Retrospective Studies; Risk; Ticlopidine; Time Factors | 2016 |
High on-treatment platelet reactivity and outcomes after percutaneous endovascular procedures in patients with peripheral artery disease.
Topics: Aged; Aspirin; Blood Platelets; Chi-Square Distribution; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Endovascular Procedures; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Peripheral Arterial Disease; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Proportional Hazards Models; Purinergic P2Y Receptor Antagonists; Recurrence; Retrospective Studies; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome | 2016 |
Platelets are dispensable for antibody-mediated transfusion-related acute lung injury in the mouse.
Topics: Animals; Antibodies, Monoclonal; Aspirin; Blood Platelets; Blood Transfusion; Clopidogrel; Diphtheria Toxin; Edema; Hemorrhage; Histocompatibility Antigens Class I; Lung; Male; Megakaryocytes; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Neutrophils; Platelet Activation; Platelet Aggregation Inhibitors; Rats; Respiratory Distress Syndrome; Signal Transduction; Thrombocytopenia; Ticlopidine; Transfusion-Related Acute Lung Injury | 2016 |
Coronary Thrombosis and Major Bleeding After PCI With Drug-Eluting Stents: Risk Scores From PARIS.
Topics: Acute Coronary Syndrome; Age Factors; Aged; Anemia; Aspirin; Body Mass Index; Clopidogrel; Cohort Studies; Coronary Thrombosis; Diabetes Mellitus; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Humans; Male; Medication Adherence; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Registries; Renal Insufficiency; Risk Assessment; Smoking; Ticlopidine; United States | 2016 |
The contemporary management of intracranial atherosclerotic disease.
Topics: Angioplasty; Aspirin; Clopidogrel; Fibrinolytic Agents; Humans; Intracranial Arteriosclerosis; Stroke; Ticlopidine | 2016 |
Parathyroid Hormone Levels and High-Residual Platelet Reactivity in Patients Receiving Dual Antiplatelet Therapy With Acetylsalicylic Acid and Clopidogrel or Ticagrelor.
Topics: Acute Coronary Syndrome; Adenosine; Adenosine Diphosphate; Aged; Aspirin; Biomarkers; Clopidogrel; Coronary Artery Disease; Databases, Factual; Drug Resistance; Drug Therapy, Combination; Female; Homeodomain Proteins; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Risk Factors; Ticagrelor; Ticlopidine; Time Factors; Transcription Factors; Treatment Outcome; Up-Regulation | 2016 |
In Vitro Effects of Pantoprazole on Platelet Aggregation in Blood Samples From Clopidogrel and Aspirin-treated Patients.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Aspirin; Clopidogrel; Cohort Studies; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Pantoprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Proton Pump Inhibitors; Ticlopidine; Treatment Outcome | 2016 |
[ST-segment elevation myocardial infarction in the eastern urban China: from 2001 to 2011].
Topics: Aged; Aspirin; China; Clopidogrel; Female; Hospitalization; Hospitals; Humans; Logistic Models; Male; Middle Aged; Percutaneous Coronary Intervention; Registries; Retrospective Studies; Risk Factors; ST Elevation Myocardial Infarction; Ticlopidine | 2016 |
[Minor head injuries under antiocoagulation-antiplatelet drugs distributed like lozenges].
Topics: Anticoagulants; Aspirin; Cerebral Hemorrhage, Traumatic; Clopidogrel; Craniocerebral Trauma; Dosage Forms; Guideline Adherence; Humans; Patient Admission; Phenprocoumon; Platelet Aggregation Inhibitors; Ticlopidine; Tomography, X-Ray Computed | 2016 |
[After the first stroke, acetylsalicylic acid is no longer enough].
Topics: Aged; Aspirin; Clopidogrel; Drug Substitution; Drug Therapy, Combination; Humans; Recurrence; Stroke; Ticlopidine | 2016 |
Continued vorapaxar versus withdrawed clopidogrel both on top of low dose aspirin in patients undergoing heart surgery: A call for randomized trial.
Topics: Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Female; Humans; Lactones; Male; Myocardial Infarction; Postoperative Hemorrhage; Pyridines; Survival Analysis; Ticlopidine; Treatment Outcome | 2016 |
Serum uric acid levels during dual antiplatelet therapy with ticagrelor or clopidogrel: Results from a single-centre study.
Topics: Acute Coronary Syndrome; Adenosine; Aged; Aspirin; Biomarkers; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Risk Factors; Ticagrelor; Ticlopidine; Time Factors; Treatment Outcome; Up-Regulation; Uric Acid | 2016 |
Antiplatelet and Anticoagulant Medications Significantly Increase the Risk of Postoperative Hematoma: Review of over 4500 Thyroid and Parathyroid Procedures.
Topics: Anticoagulants; Aspirin; Clopidogrel; Female; Hematoma; Humans; Male; Middle Aged; Parathyroidectomy; Platelet Aggregation Inhibitors; Postoperative Complications; Retrospective Studies; Risk Factors; Thyroidectomy; Ticlopidine | 2016 |
Extended use of clopidogrel and aspirin after ischemic stroke.
Topics: Aspirin; Clopidogrel; Drug Administration Schedule; Humans; Platelet Aggregation Inhibitors; Post-Exposure Prophylaxis; Stroke; Ticlopidine | 2016 |
Extended use of clopidogrel and aspirin after ischemic stroke.
Topics: Aspirin; Brain Ischemia; Clopidogrel; Drug Administration Schedule; Humans; Platelet Aggregation Inhibitors; Post-Exposure Prophylaxis; Stroke; Ticlopidine | 2016 |
Initiation and persistence with dual antiplatelet therapy after acute myocardial infarction: a Danish nationwide population-based cohort study.
Topics: Adenosine; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Cohort Studies; Denmark; Drug Prescriptions; Drug Therapy, Combination; Female; Humans; Male; Medication Adherence; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Registries; Ticagrelor; Ticlopidine | 2016 |
Coronary artery bypass grafting-related bleeding complications in patients treated with dual antiplatelet treatment.
Topics: Adenosine; Aged; Aspirin; Blood Transfusion; Clopidogrel; Coronary Artery Bypass; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Care; Postoperative Hemorrhage; Preoperative Care; Retrospective Studies; Ticagrelor; Ticlopidine | 2016 |
Complication of Stenting in Intracranial Arterial Stenosis.
Topics: Age Factors; Aged; Angioplasty; Aspirin; China; Clopidogrel; Computed Tomography Angiography; Constriction, Pathologic; Female; Follow-Up Studies; Humans; Intracranial Arteriosclerosis; Kaplan-Meier Estimate; Male; Middle Aged; Perioperative Period; Postoperative Complications; Proportional Hazards Models; Recurrence; Retrospective Studies; Risk Factors; Stents; Ticlopidine; Treatment Outcome | 2016 |
[Safety of implantation permanent pacemaker at different times in patients with dual antiplatelet therapy].
Topics: Anticoagulants; Aspirin; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Hematoma; Hemorrhage; Heparin, Low-Molecular-Weight; Humans; Pacemaker, Artificial; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2016 |
Utility of the HAS-BLED Score in Risk Stratifying Patients on Dual Antiplatelet Therapy Post 12 Months After Drug-Eluting Stent Placement.
Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Female; Follow-Up Studies; Georgia; Hemorrhage; Humans; Incidence; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Period; Purinergic P2Y Receptor Antagonists; Retrospective Studies; Risk Assessment; Ticlopidine; Time Factors | 2017 |
Endovascular Treatment of 147 Cases of Cavernous Carotid Aneurysms: A Single-Center Experience.
Topics: Adult; Aspirin; Cerebral Angiography; Clopidogrel; Embolization, Therapeutic; Female; Follow-Up Studies; Heart Aneurysm; Humans; Intracranial Aneurysm; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Ticlopidine; Treatment Outcome | 2016 |
Aspirin, but not clopidogrel, ameliorates vasomotor symptoms due to essential thrombocythemia: A case report.
Topics: Aspirin; Clopidogrel; Drug Resistance; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Thrombocythemia, Essential; Ticlopidine; Vasomotor System | 2016 |
Exome sequencing of extreme clopidogrel response phenotypes identifies B4GALT2 as a determinant of on-treatment platelet reactivity.
Topics: Adult; Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Exome; Female; Galactosyltransferases; Genotype; Humans; Male; Middle Aged; Phenotype; Pilot Projects; Platelet Aggregation Inhibitors; Ticlopidine | 2016 |
[Comment on “Individual Proton Pump Inhibitors and Outcomes in Patients With Coronary Artery Disease on Dual Antiplatelet Therapy: A Systematic Review”].
Topics: Aspirin; Coronary Artery Disease; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine; Treatment Outcome | 2016 |
Bleeding complications of triple antithrombotic therapy after percutaneous coronary interventions.
Topics: Administration, Oral; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Drug Therapy, Combination; Female; Fibrinolytic Agents; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Ohio; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proportional Hazards Models; Retrospective Studies; Risk Factors; Stents; Ticlopidine; Time Factors; Treatment Outcome; Warfarin | 2017 |
Effect of a combination of antiplatelet and antithrombotic pretreatment on myocardial perfusion in patients with an acute ST-segment elevation myocardial infarction undergoing a primary percutaneous coronary intervention.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Biomarkers; Clopidogrel; Coronary Angiography; Coronary Circulation; Drug Therapy, Combination; Electrocardiography; Female; Fibrinolytic Agents; Heparin; Humans; Male; Middle Aged; Patient Transfer; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prospective Studies; ST Elevation Myocardial Infarction; Ticlopidine; Time Factors; Time-to-Treatment; Treatment Outcome; Troponin T | 2016 |
High On-Treatment Platelet Reactivity in Peripheral Arterial Disease: A Pilot Study to Find the Optimal Test and Cut Off Values.
Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Drug Therapy, Combination; Female; Humans; Male; Peripheral Arterial Disease; Pilot Projects; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Purinergic P2Y Receptor Antagonists; Ticlopidine | 2016 |
Effects of Sarpogrelate Combined with Aspirin in Patients Undergoing Carotid Endarterectomy in China: A Single-Center Retrospective Study.
Topics: Aged; Aspirin; Blood Loss, Surgical; Carotid Stenosis; China; Clopidogrel; Drug Therapy, Combination; Endarterectomy, Carotid; Female; Hematoma; Humans; Male; Middle Aged; Operative Time; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Succinates; Ticlopidine; Time Factors; Treatment Outcome | 2016 |
Deciphering glycomics and neuroproteomic alterations in experimental traumatic brain injury: Comparative analysis of aspirin and clopidogrel treatment.
Topics: Animals; Aspirin; Brain Injuries, Traumatic; Cerebellar Cortex; Clopidogrel; Gene Expression Regulation; Glycomics; Glycosylation; Humans; Male; Platelet Aggregation Inhibitors; Protein Processing, Post-Translational; Proteomics; Rats; Rats, Sprague-Dawley; Ticlopidine | 2016 |
[THE FIRST RESULTS OF THE PREVALENCE OF CYP2C19 GENEPOLYMORPHISM IN PATIENTS WITH ACUTE CORONARY SYNDROME IN THE AKTYUBINSK POPULATION].
Topics: Acute Coronary Syndrome; Adult; Aged; Asian People; Aspirin; Clopidogrel; Cytochrome P-450 CYP2C19; Female; Genetic Association Studies; Humans; Kazakhstan; Male; Middle Aged; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Ticlopidine; White People | 2016 |
[The incidence, clinical characteristics and risk factors of upper gastrointestinal bleeding in patients taking dual antiplatelet therapy after percutaneous coronary intervention in south China].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; China; Clopidogrel; Coronary Artery Disease; Female; Gastrointestinal Hemorrhage; Humans; Incidence; Male; Peptic Ulcer; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Ticlopidine; Upper Gastrointestinal Tract | 2016 |
Antiplatelet drug resistance is associated with early neurological deterioration in acute minor ischemic stroke in the Chinese population.
Topics: Aged; Aged, 80 and over; Asian People; Aspirin; Brain Ischemia; Clopidogrel; Female; Humans; Male; Middle Aged; Nervous System Diseases; Platelet Aggregation Inhibitors; Risk Factors; Stroke; Ticlopidine; Treatment Outcome | 2016 |
A rabbit model of cerebral microembolic signals for translational research: preclinical validation for aspirin and clopidogrel.
Topics: Animals; Aspirin; Carotid Artery Thrombosis; Chlorides; Clopidogrel; Disease Models, Animal; Drug Evaluation, Preclinical; Ferric Compounds; Fibrinolytic Agents; Intracranial Embolism; Male; Middle Cerebral Artery; Platelet Aggregation; Rabbits; Stroke; Ticlopidine; Translational Research, Biomedical; Ultrasonography; Ultrasonography, Doppler | 2016 |
A State Transition Model for Health Outcomes Associated with Vorapaxar Treatment as an Add-on to Standard Care Antiplatelet Therapy in the Prevention of Thrombotic Events for Patients with a Recent Myocardial Infarction.
Topics: Aspirin; Cardiovascular System; Clopidogrel; Hemorrhage; Humans; Lactones; Myocardial Infarction; Platelet Aggregation Inhibitors; Pyridines; Secondary Prevention; Stroke; Thrombosis; Ticlopidine; Treatment Outcome | 2016 |
Dual Antiplatelet Therapy in the Prevention of Recurrent Ischemic Events.
Topics: Aspirin; Brain Ischemia; Drug Therapy, Combination; Humans; Ischemia; Platelet Aggregation Inhibitors; Ticlopidine | 2016 |
High platelet reactivity on aspirin in patients with acute ST elevation myocardial infarction.
Topics: Acute Disease; Adenosine; Aspirin; Blood Platelets; Brain Ischemia; Cardiovascular Diseases; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Prospective Studies; Purinergic P2Y Receptor Antagonists; ST Elevation Myocardial Infarction; Survival Analysis; Ticagrelor; Ticlopidine | 2016 |
Incidence and Clinical Features of Early Stent Thrombosis in the Era of New P2y12 Inhibitors (PLATIS-2).
Topics: Acute Coronary Syndrome; Adenosine; Aged; Aspirin; Clopidogrel; Early Diagnosis; Female; Humans; Israel; Male; Middle Aged; Multivariate Analysis; Percutaneous Coronary Intervention; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Registries; Stents; Stroke; Survival Analysis; Thrombosis; Ticagrelor; Ticlopidine | 2016 |
[ANMCO/SIC/SICI-GISE/SICCH Consensus document: Clinical approach to pharmacological pretreatment for patients undergoing myocardial revascularization].
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Drug Therapy, Combination; Fondaparinux; Heparin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Italy; Myocardial Revascularization; Platelet Aggregation Inhibitors; Polysaccharides; Preoperative Care; Ticlopidine; Treatment Outcome | 2016 |
[Retrospective cohort study for the impact on readmission of patients with ischemic stroke after treatment of aspirin plus clopidogrel or aspirin mono-therapy].
Topics: Aspirin; Beijing; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Myocardial Infarction; Patient Readmission; Platelet Aggregation Inhibitors; Proportional Hazards Models; Recurrence; Retrospective Studies; Secondary Prevention; Stroke; Ticlopidine | 2016 |
Measurement of residual platelet thrombogenicity under arterial shear conditions in cerebrovascular disease patients receiving antiplatelet therapy.
Topics: Adult; Aged; Arteries; Aspirin; Blood Coagulation Tests; Blood Platelets; Carotid Arteries; Cell Adhesion Molecules; Cerebrovascular Circulation; Cerebrovascular Disorders; Clopidogrel; Constriction, Pathologic; Cross-Sectional Studies; Female; Humans; Male; Microfilament Proteins; Middle Aged; P-Selectin; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Shear Strength; Thrombosis; Ticlopidine; Vasodilator Agents; Young Adult | 2016 |
High-Sensitive C-Reactive Protein Predicts Recurrent Stroke and Poor Functional Outcome: Subanalysis of the Clopidogrel in High-Risk Patients With Acute Nondisabling Cerebrovascular Events Trial.
Topics: Aged; Aspirin; C-Reactive Protein; Clopidogrel; Drug Therapy, Combination; Female; Humans; Incidence; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Recurrence; Stroke; Ticlopidine | 2016 |
Dynamic platelet adhesion in patients with an acute coronary syndrome: The effect of antiplatelet therapy.
Topics: Acute Coronary Syndrome; Adenosine; Aged; Aspirin; Biomarkers; Blood Platelets; Case-Control Studies; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticagrelor; Ticlopidine; Treatment Outcome | 2016 |
The Impact of Timing of Ischemic and Hemorrhagic Events on Mortality After Percutaneous Coronary Intervention: The ADAPT-DES Study.
Topics: Aged; Aspirin; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Drug-Eluting Stents; Female; Germany; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proportional Hazards Models; Prospective Studies; Registries; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome; United States | 2016 |
Optimizing prevention and guideline-concordant care in Montenegro.
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Cardiovascular Agents; Clopidogrel; Evidence-Based Medicine; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Medication Adherence; Middle Aged; Montenegro; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Prospective Studies; Ticlopidine | 2016 |
Ticagrelor for left ventricular assist device thrombosis: A new therapeutic option to be evaluated with caution.
Topics: Adenosine; Aged; Aspirin; Blood Coagulation; Cardiomyopathies; Clopidogrel; Drug Substitution; Drug Therapy, Combination; Fibrinolytic Agents; Heart-Assist Devices; Humans; Male; Medication Therapy Management; Postoperative Complications; Risk Adjustment; Thrombosis; Ticagrelor; Ticlopidine; Treatment Outcome | 2016 |
The Effect of Antiplatelet Agents on Bleeding-Related Complications After Ureteroscopy.
Topics: Adenosine; Adult; Aged; Anticoagulants; Aspirin; Blood Platelets; Clopidogrel; Female; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Retrospective Studies; Risk; Ticagrelor; Ticlopidine; Ureteroscopy | 2016 |
Aspirin and Clopidogrel Inhibit Aneurysm Healing after HydroCoil Implantation in External Carotid Artery Aneurysm Model.
Topics: Aneurysm; Animals; Aspirin; Carotid Artery Diseases; Carotid Artery, External; Cell Movement; Clopidogrel; Disease Models, Animal; Drug Therapy, Combination; Embolization, Therapeutic; Equipment Design; Macrophages; Male; Platelet Aggregation Inhibitors; Platinum; Rats, Sprague-Dawley; Ticlopidine; Time Factors; Wound Healing | 2016 |
Dual-Antiplatelet Therapy: Why Stop Now?
Topics: Aspirin; Drug Therapy, Combination; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticlopidine | 2016 |
Locked Away: Percutaneous Closure of a Malignant Left Atrial Appendage to Constrain an Unresolvable Thrombus.
Topics: Aged; Aspirin; Atrial Appendage; Atrial Fibrillation; Catheter Ablation; Clopidogrel; Combined Modality Therapy; Coronary Angiography; Echocardiography, Transesophageal; Factor Xa Inhibitors; Humans; Male; Platelet Aggregation Inhibitors; Rivaroxaban; Septal Occluder Device; Thrombosis; Ticlopidine; Vitamin K | 2016 |
The Impact of Type 2 Diabetes on the Efficacy of ADP Receptor Blockers in Patients with Acute ST Elevation Myocardial Infarction: A Pilot Prospective Study.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Case-Control Studies; Clopidogrel; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Flow Cytometry; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Prospective Studies; Purinergic P2Y Receptor Antagonists; ST Elevation Myocardial Infarction; Ticlopidine | 2016 |
Dual antiplatelet therapy and an anemia subtype.
Topics: Anemia; Aspirin; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2018 |
Antithrombotic Medication Use and Misuse Among Patients with Intracranial Hemorrhage: A 16-Year, Lebanese, Single-Center Experience.
Topics: Acenocoumarol; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Cerebral Hemorrhage; Clopidogrel; Coronary Artery Disease; Enoxaparin; Female; Fibrinolytic Agents; Humans; Inappropriate Prescribing; Intracranial Hemorrhages; Lebanon; Male; Middle Aged; Platelet Aggregation Inhibitors; Prescription Drug Misuse; Retrospective Studies; Risk Factors; Stroke; Ticlopidine; Warfarin; Young Adult | 2016 |
[CHARISMA study].
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Embolism; Female; Humans; Male; Middle Aged; Plaque, Atherosclerotic; Platelet Aggregation Inhibitors; Ticlopidine | 2016 |
Changes in response to clopidogrel therapy in patients after percutaneous coronary interventions as assessed by different platelet function tests.
Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2016 |
Microparticles and blood cells induce procoagulant activity via phosphatidylserine exposure in NSTEMI patients following stent implantation.
Topics: Aged; Aspirin; Blood Cells; Blood Coagulation; Cell-Derived Microparticles; Clopidogrel; Female; Humans; Male; Middle Aged; Non-ST Elevated Myocardial Infarction; Percutaneous Coronary Intervention; Phosphatidylserines; Platelet Aggregation Inhibitors; Statistics as Topic; Stents; Thrombophilia; Ticlopidine | 2016 |
Antiplatelet Therapy is Associated with a Better Prognosis for Patients with Hepatitis B Virus-Related Hepatocellular Carcinoma after Liver Resection.
Topics: Adult; Aged; Aspirin; Carcinoma, Hepatocellular; Clopidogrel; Disease-Free Survival; Female; Gastrointestinal Hemorrhage; Hepatectomy; Hepatitis B, Chronic; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Platelet Aggregation Inhibitors; Proportional Hazards Models; Risk Factors; Survival Rate; Taiwan; Ticlopidine | 2016 |
CASE 11-2016 Perioperative Coronary Thrombosis in a Patient With Multiple Second-Generation Drug-Eluting Stents: Is It Time for a Paradigm Shift?
Topics: Analgesics, Opioid; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Coronary Thrombosis; Drug-Eluting Stents; Female; Humans; Metoprolol; Middle Aged; Morphine; Myocardial Infarction; Nitroglycerin; Ovarian Neoplasms; Perioperative Care; Platelet Aggregation Inhibitors; Postoperative Complications; Retreatment; Ticlopidine; Treatment Outcome; Vasodilator Agents | 2016 |
A retrospective study showing the extent of compliance with perioperative guidelines in patients with coronary stents with regard to double antiplatelet therapy.
Topics: Aged; Aged, 80 and over; Aspirin; Case Management; Clopidogrel; Coronary Vessels; Female; Guideline Adherence; Humans; Male; Middle Aged; Perioperative Care; Platelet Aggregation Inhibitors; Retrospective Studies; Stents; Ticlopidine; Treatment Outcome | 2016 |
Clopidogrel use After Myocardial Revascularization: Prevalence, Predictors, and One-Year Survival Rate.
Topics: Aspirin; Cardiopulmonary Bypass; Clopidogrel; Coronary Artery Bypass; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Revascularization; North Carolina; Patient Discharge; Platelet Aggregation Inhibitors; Postoperative Care; Postoperative Complications; Postoperative Period; Prevalence; Prognosis; Survival Rate; Ticlopidine | 2016 |
High Risk of Gastrointestinal Bleeding on Dual Antiplatelet Treatment.
Topics: Aspirin; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2016 |
Reply: High Risk of Gastrointestinal Bleeding on Dual Antiplatelet Treatment.
Topics: Aspirin; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2016 |
Risk of bleeding after hospitalization for a serious coronary event: a retrospective cohort study with nested case-control analyses.
Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Clopidogrel; Confidence Intervals; Coronary Artery Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Hospitalization; Humans; Incidence; Male; Middle Aged; Odds Ratio; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Survival Rate; Ticlopidine; United Kingdom | 2016 |
Efficacy and Safety of Dual Antiplatelet Therapy After Complex PCI.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Complications; Randomized Controlled Trials as Topic; Ticlopidine; Time Factors; Treatment Outcome | 2016 |
Effect of Drugs Associated With Bleeding Tendency on the Complications and Outcomes of Transforaminal Epidural Steroid Injection.
Topics: Aged; alpha-Cyclodextrins; Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Clopidogrel; Female; Follow-Up Studies; Hemorrhage; Humans; Injections, Epidural; Male; Middle Aged; Pain; Pain Measurement; Platelet Aggregation Inhibitors; Retrospective Studies; Steroids; Ticlopidine; Time Factors; Treatment Outcome | 2017 |
Stent-assisted coiling in ruptured cerebral aneurysms: multi-center experience in acute phase.
Topics: Acute Disease; Aneurysm, Ruptured; Aspirin; Clopidogrel; Embolization, Therapeutic; Female; Humans; Intracranial Aneurysm; Male; Middle Aged; Neuroimaging; Platelet Aggregation Inhibitors; Radiography, Interventional; Retrospective Studies; Stents; Ticlopidine; Tomography, X-Ray Computed; Treatment Outcome | 2017 |
Head to Head Comparison of Two Point-of-care Platelet Function Tests Used for Assessment of On-clopidogrel Platelet Reactivity in Chinese Acute Myocardial Infarction Patients Undergoing Percutaneous Coronary Intervention.
Topics: Adenosine Diphosphate; Aged; Aspirin; Blood Platelets; China; Clopidogrel; Female; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Point-of-Care Systems; Receptors, Purinergic P2Y12; Thrombelastography; Ticlopidine | 2016 |
Increased Platelet-leukocyte Aggregates Are Associated With Myocardial No-reflow in Patients With ST Elevation Myocardial Infarction.
Topics: Aspirin; Blood Platelets; Clopidogrel; Coronary Angiography; Coronary Circulation; Coronary Thrombosis; Electrocardiography; Female; Flow Cytometry; Humans; Leukocytes; Male; Middle Aged; Myocardial Infarction; No-Reflow Phenomenon; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Predictive Value of Tests; Retrospective Studies; Ticlopidine | 2016 |
Impact of proton pump inhibitors and dual antiplatelet therapy cessation on outcomes following percutaneous coronary intervention: Results From the PARIS Registry.
Topics: Aged; Aspirin; Clopidogrel; Coronary Thrombosis; Drug Administration Schedule; Drug Antagonism; Drug Therapy, Combination; Europe; Female; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proportional Hazards Models; Prospective Studies; Proton Pump Inhibitors; Registries; Risk Factors; Stents; Ticlopidine; Time Factors; Treatment Outcome; United States | 2017 |
Rare case of bilateral traumatic internal carotid artery dissection.
Topics: Aspirin; Carotid Artery, Internal, Dissection; Clopidogrel; Headache; Humans; Infarction, Anterior Cerebral Artery; Male; Middle Aged; Neurologic Examination; Oculomotor Nerve Diseases; Platelet Aggregation Inhibitors; Ticlopidine; Tomography, X-Ray Computed; Treatment Outcome; Whole Body Imaging | 2016 |
Contribution of whole platelet aggregometry to the endovascular management of unruptured aneurysms: an institutional experience.
Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Disease Management; Endovascular Procedures; Female; Humans; Intracranial Aneurysm; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Registries; Retrospective Studies; Stents; Ticlopidine | 2017 |
Impact of Anticoagulant and Antiplatelet Drugs on Perioperative Outcomes of Robotic-assisted Partial Nephrectomy.
Topics: Administration, Oral; Aged; Anticoagulants; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Kidney Neoplasms; Male; Middle Aged; Morbidity; Nephrectomy; Perioperative Care; Platelet Aggregation Inhibitors; Postoperative Complications; Retrospective Studies; Robotic Surgical Procedures; Ticlopidine | 2017 |
Ticagrelor versus Aspirin in Acute Stroke or Transient Ischemic Attack.
Topics: Aspirin; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Treatment Outcome | 2016 |
Ticagrelor versus Aspirin in Acute Stroke or Transient Ischemic Attack.
Topics: Aspirin; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Treatment Outcome | 2016 |
Ticagrelor versus Aspirin in Acute Stroke or Transient Ischemic Attack.
Topics: Aspirin; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Treatment Outcome | 2016 |
Antiplatelet therapy: What have we learned from the ANTARCTIC trial?
Topics: Acute Coronary Syndrome; Aged; Aspirin; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2016 |
Letter by Petrie Regarding Article, "Individualizing Duration of Dual Antiplatelet Therapy After Acute Coronary Syndrome or Percutaneous Coronary Intervention".
Topics: Acute Coronary Syndrome; Aspirin; Drug Therapy, Combination; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticlopidine | 2016 |
Response by Bagai et al to Letter Regarding Article, "Individualizing Duration of Dual Antiplatelet Therapy After Acute Coronary Syndrome or Percutaneous Coronary Intervention".
Topics: Acute Coronary Syndrome; Aspirin; Drug Therapy, Combination; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticlopidine | 2016 |
Left ventricular non-compaction cardiomyopathy: Incidental diagnosis after ST-elevation myocardial infarction.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Cardiomyopathy, Hypertrophic, Familial; Clopidogrel; Coronary Angiography; Drug-Eluting Stents; Echocardiography, Doppler, Color; Electrocardiography; Female; Hematologic Agents; Humans; Incidental Findings; ST Elevation Myocardial Infarction; Thrombosis; Ticlopidine; Treatment Outcome; Warfarin | 2016 |
Prasugrel versus clopidogrel in stent-assisted coil embolization of unruptured intracranial aneurysms.
Topics: Adult; Aged; Aspirin; Clopidogrel; Combined Modality Therapy; Drug Therapy, Combination; Embolization, Therapeutic; Female; Humans; Intracranial Aneurysm; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Prasugrel Hydrochloride; Stents; Ticlopidine; Treatment Outcome | 2017 |
Selecting the Duration of Antiplatelet Therapy Following Percutaneous Coronary Intervention: A Complex Decision or Not?
Topics: Aspirin; Drug Therapy, Combination; Drug-Eluting Stents; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2016 |
Impact of different antithrombotics on the microcirculation and viability of perforator-based ischaemic skin flaps in a small animal model.
Topics: Animals; Aspirin; Clopidogrel; Disease Models, Animal; Fibrinolytic Agents; Graft Survival; Heparin; Hirudins; Ischemia; Laser-Doppler Flowmetry; Male; Microcirculation; Pentoxifylline; Postoperative Complications; Rats; Rats, Wistar; Skin Diseases; Skin Transplantation; Surgical Flaps; Ticlopidine | 2016 |
Letter by Moris and Avgerinos Regarding Article, "Recurrent Ischemic Lesions After Acute Atherothrombotic Stroke: Clopidogrel Plus Aspirin Versus Aspirin Alone".
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2016 |
Single versus double antiplatelet therapy in patients undergoing coronary artery bypass grafting with coronary endarterectomy: mid-term results and clinical implications.
Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Drug Therapy, Combination; Endarterectomy; Female; Follow-Up Studies; Hospital Mortality; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Retrospective Studies; Ticlopidine; Treatment Outcome | 2017 |
Thrombogenicity of flow diverters in an ex vivo shunt model: effect of phosphorylcholine surface modification.
Topics: Animals; Arteriovenous Shunt, Surgical; Aspirin; Clopidogrel; Embolization, Therapeutic; Intracranial Aneurysm; Intracranial Thrombosis; Male; Papio anubis; Phosphorylcholine; Platelet Aggregation; Stents; Surface Properties; Ticlopidine | 2017 |
Relationship of Platelet Reactivity With Bleeding Outcomes During Long-Term Treatment With Dual Antiplatelet Therapy for Medically Managed Patients With Non-ST-Segment Elevation Acute Coronary Syndromes.
Topics: Acute Coronary Syndrome; Aged; Angina, Unstable; Aspirin; Blood Platelets; Clopidogrel; Drug Therapy, Combination; Female; Hemorrhage; Humans; Longitudinal Studies; Male; Middle Aged; Non-ST Elevated Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Proportional Hazards Models; Randomized Controlled Trials as Topic; Ticlopidine | 2016 |
Association between antithrombotic treatment and hemorrhagic stroke in patients with atrial fibrillation-a cohort study in primary care.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Cohort Studies; Female; Fibrinolytic Agents; Humans; Intracranial Hemorrhages; Male; Middle Aged; Platelet Aggregation Inhibitors; Primary Health Care; Stroke; Sweden; Ticlopidine; Warfarin | 2017 |
A 55-Year-Old Woman With Pulmonary Hypertension, Worsening Dyspnea, and Chest Pain.
Topics: Angina Pectoris; Aspirin; Clopidogrel; Compartment Syndromes; Coronary Vessels; Diagnosis, Differential; Dyspnea; Female; Humans; Hypertension, Pulmonary; Middle Aged; Patient Care Management; Platelet Aggregation Inhibitors; Pulmonary Artery; Ticlopidine; Treatment Outcome | 2014 |
Time-To-Treatment of Acute Coronary Syndrome and Unit of First Contact in the ERICO Study.
Topics: Acute Coronary Syndrome; Aged; Anticoagulants; Aspirin; Brazil; Clopidogrel; Educational Status; Female; Fibrinolytic Agents; Heparin; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Primary Health Care; Prospective Studies; Statistics, Nonparametric; Ticlopidine; Time Factors; Time-to-Treatment | 2016 |
Long-term outcomes in patients with acute coronary syndromes related to prolonging dual antiplatelet therapy more than 12 months after coronary stenting.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Databases, Factual; Drug Administration Schedule; Drug Therapy, Combination; Female; Hemorrhage; Hospitals, Veterans; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Propensity Score; Proportional Hazards Models; Prosthesis Design; Risk Factors; Stents; Ticlopidine; Time Factors; Treatment Outcome; United States; United States Department of Veterans Affairs | 2017 |
ABCC3 Polymorphisms and mRNA Expression Influence the Concentration of a Carboxylic Acid Metabolite in Patients on Clopidogrel and Aspirin Therapy.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Carboxylic Acids; Chromatography, Liquid; Clopidogrel; Cytochrome P-450 CYP2C19; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Genotype; Humans; Male; Middle Aged; Multidrug Resistance-Associated Proteins; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polymorphism, Genetic; RNA, Messenger; Salicylic Acid; Tandem Mass Spectrometry; Ticlopidine; Up-Regulation | 2017 |
Long-term versus short-term dual antiplatelet therapy was similarly associated with a lower risk of death, stroke, or infarction in patients with acute coronary syndrome regardless of underlying kidney disease.
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Creatinine; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Prospective Studies; Registries; Renal Insufficiency, Chronic; Risk Assessment; Stroke; Ticlopidine; Time Factors; Treatment Outcome | 2017 |
Tutorial on statistical considerations on subgroup analysis in confirmatory clinical trials.
Topics: Aspirin; Clopidogrel; Data Interpretation, Statistical; Humans; Models, Statistical; Myocardial Infarction; Protein C; Randomized Controlled Trials as Topic; Recombinant Proteins; Reproducibility of Results; Sepsis; Statistics as Topic; Stroke; Survival Analysis; Ticlopidine; Treatment Outcome | 2017 |
High platelet reactivity affects the clinical outcomes of patients undergoing percutaneous coronary intervention.
Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Female; Follow-Up Studies; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Retrospective Studies; Ticlopidine; Time Factors | 2016 |
Mortality in patients who discontinue low-dose acetylsalicylic acid therapy after upper gastrointestinal bleeding.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Primary Health Care; Proportional Hazards Models; Retrospective Studies; Risk Factors; Sex Factors; Ticlopidine; Time Factors; United Kingdom | 2017 |
W1, a Novel Oral Antiplatelet Agent With Less Resistance Than Clopidogrel.
Topics: Administration, Oral; Animals; Aspirin; Clopidogrel; Drug Combinations; Drug Resistance; Mice; Platelet Aggregation; Platelet Aggregation Inhibitors; Random Allocation; Rats; Rats, Wistar; Ticlopidine | 2017 |
Decade-long temporal trends in the utilization of preventive medicines by centenarians.
Topics: Aged, 80 and over; Anticoagulants; Aspirin; Clopidogrel; Cross-Sectional Studies; Drug Utilization; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Preventive Medicine; Ticlopidine | 2017 |
Proposal of a "gradient model" to evaluate residual platelet activity on antiplatelet therapy: A pilot study.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Platelets; Clopidogrel; Drug Resistance; Electric Impedance; Female; Humans; Male; Middle Aged; Pilot Projects; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2017 |
Nonsteroidal anti-inflammatory drugs-induced small bowel enteropathy and obscure gastrointestinal bleeding.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Capsule Endoscopy; Case-Control Studies; Clopidogrel; Comorbidity; Coronary Disease; Female; Gastrointestinal Hemorrhage; Humans; Intestinal Diseases; Logistic Models; Male; Multivariate Analysis; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Retrospective Studies; Risk Factors; Ticlopidine | 2018 |
Atrial Fibrillation and PCI - Do We Still Need Aspirin?
Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Cerebrovascular Disorders; Humans; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine; Warfarin | 2016 |
Platelet aggregation and the risk of stent thrombosis or bleeding in elective percutaneous coronary intervention patients.
Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Thrombosis; Elective Surgical Procedures; Female; Hemorrhage; Humans; Male; Middle Aged; Odds Ratio; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Risk Factors; Stents; Ticlopidine | 2017 |
Antiplatelet Strategies and Outcomes in Patients with Noncardioembolic Ischemic Stroke from a Real-World Study with a Five-Year Follow-Up.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; China; Clopidogrel; Drug Therapy, Combination; Female; Follow-Up Studies; Hemorrhage; Humans; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Secondary Prevention; Stroke; Ticlopidine; Treatment Outcome | 2017 |
Submucosal Hematoma of the Sigmoid Colon Due to Anticoagulation Therapy.
Topics: Anticoagulants; Aspirin; Clopidogrel; Colon, Sigmoid; Colonoscopy; Diagnosis, Differential; Hematoma; Humans; Intestinal Mucosa; Male; Middle Aged; Sigmoid Diseases; Ticlopidine; Tomography, X-Ray Computed | 2017 |
Pump Thrombosis following HeartMate II Left Ventricular Assist Device Implantation in a Patient with Aspirin and Plavix Resistance.
Topics: Aged; Aspirin; Clopidogrel; Drug Resistance; Heart Failure; Heart-Assist Devices; Humans; Male; Platelet Aggregation Inhibitors; Prosthesis Failure; Retrospective Studies; Thrombosis; Ticlopidine | 2016 |
Percutaneous left atrial appendage closure followed by single antiplatelet therapy: Short- and mid-term outcomes.
Topics: Aged; Aged, 80 and over; Aspirin; Atrial Appendage; Atrial Fibrillation; Cardiac Catheterization; Clopidogrel; Drug Administration Schedule; Female; France; Hemorrhage; Humans; Male; Platelet Aggregation Inhibitors; Prospective Studies; Registries; Stroke; Thrombosis; Ticlopidine; Time Factors; Tomography, X-Ray Computed; Treatment Outcome | 2017 |
Platelet reactivity in human immunodeficiency virus infected patients on dual antiplatelet therapy for an acute coronary syndrome: the EVERE2ST-HIV study.
Topics: Acute Coronary Syndrome; Adenosine; Anti-HIV Agents; Aspirin; Blood Platelets; Clopidogrel; Cross-Sectional Studies; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Prospective Studies; Purinergic P2Y Receptor Antagonists; Recurrence; Risk Factors; Ticagrelor; Ticlopidine | 2017 |
Decreased platelet responsiveness to clopidogrel correlates with CYP2C19 and PON1 polymorphisms in atherosclerotic patients.
Topics: Alleles; Aryldialkylphosphatase; Aspirin; ATP Binding Cassette Transporter, Subfamily B; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Female; Genotype; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Prospective Studies; Ticlopidine | 2017 |
Dual Antiplatelet Therapy Versus Aspirin Monotherapy in Diabetics With Multivessel Disease Undergoing CABG: FREEDOM Insights.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Cause of Death; Clopidogrel; Diabetic Angiopathies; Drug Therapy, Combination; Drug Utilization; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Postoperative Care; Postoperative Complications; Proportional Hazards Models; Stroke; Survival Rate; Ticlopidine | 2017 |
Adding CABG to the Dual Antiplatelet Salad.
Topics: Aspirin; Coronary Artery Bypass; Diabetes Mellitus; Freedom; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2017 |
Effect of Clopidogrel by Smoking Status on Secondary Stroke Prevention.
Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Datasets as Topic; Drug Therapy, Combination; Humans; Kaplan-Meier Estimate; Multicenter Studies as Topic; Myocardial Infarction; Platelet Aggregation Inhibitors; Proportional Hazards Models; Risk Factors; Secondary Prevention; Smoking; Stroke; Ticlopidine | 2017 |
Portal Vein Thrombosis in Patients With Cirrhosis Undergoing Elective Transjugular Intrahepatic Portosystemic Shunt: Risk Factors, Warfarin Efficacy, and Clinical Outcomes.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Elective Surgical Procedures; Female; Fibrosis; Humans; Male; Middle Aged; Portal Vein; Portasystemic Shunt, Transjugular Intrahepatic; Risk Factors; Ticlopidine; Treatment Outcome; Venous Thrombosis; Warfarin | 2018 |
Risk Factors of Subacute Thrombosis After Intracranial Stenting for Symptomatic Intracranial Arterial Stenosis.
Topics: Adult; Aged; Aspirin; Clopidogrel; Constriction, Pathologic; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Stents; Thrombosis; Ticlopidine | 2017 |
Clopidogrel and ischemic stroke outcomes by smoking status: Smoker's paradox?
Topics: Aspirin; Brain Ischemia; Clopidogrel; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Recurrence; Retrospective Studies; Smoking; Stroke; Ticlopidine; Treatment Outcome | 2017 |
Editor's Choice - Dual Antiplatelet Therapy Improves Outcome in Diabetic Patients Undergoing Endovascular Femoropopliteal Stenting for Critical Limb Ischaemia.
Topics: Adult; Aged; Aged, 80 and over; Amputation, Surgical; Aspirin; Clopidogrel; Constriction, Pathologic; Critical Illness; Diabetic Angiopathies; Drug Therapy, Combination; Endovascular Procedures; Female; Femoral Artery; Humans; Ischemia; Kaplan-Meier Estimate; Limb Salvage; Male; Middle Aged; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Popliteal Artery; Proportional Hazards Models; Registries; Retrospective Studies; Risk Factors; Stents; Sweden; Ticlopidine; Time Factors; Treatment Outcome | 2017 |
The CYP2C19*2 and CYP2C19*17 Polymorphisms play a Vital Role in Clopidogrel Responsiveness after Percutaneous Coronary Intervention: A Pharmacogenomics Study.
Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Gene Frequency; Genotype; Humans; Male; Middle Aged; Myocardial Ischemia; Percutaneous Coronary Intervention; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Postoperative Complications; Sequence Analysis, DNA; Stents; Thrombosis; Ticlopidine; Treatment Outcome; Turkey | 2017 |
The budget impact of using enteric-coated aspirin 325 mg + immediate-release omeprazole 40 mg to prevent recurrent cardiovascular events.
Topics: Adult; Aged; Aspirin; Budgets; Cardiovascular Diseases; Clopidogrel; Drug Combinations; Female; Gastrointestinal Diseases; Humans; Male; Markov Chains; Medication Adherence; Middle Aged; Models, Econometric; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Secondary Prevention; Ticlopidine | 2017 |
Novel role of platelet reactivity in adverse left ventricular remodelling after ST-segment elevation myocardial infarction: The REMODELING Trial.
Topics: Aged; Aspirin; Biomarkers; Blood Platelets; C-Reactive Protein; Chi-Square Distribution; Clopidogrel; Echocardiography; Female; Humans; Inflammation Mediators; Linear Models; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Percutaneous Coronary Intervention; Platelet Activation; Platelet Aggregation Inhibitors; Prospective Studies; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; ST Elevation Myocardial Infarction; Stents; Ticlopidine; Time Factors; Treatment Outcome; Ventricular Function, Left; Ventricular Remodeling | 2017 |
Pulmonary alveolar hemorrhage mimicking a pneumopathy: a rare complication of dual antiplatelet therapy for ST elevation myocardial infarction.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Hemorrhage; Humans; Lung Diseases; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Pulmonary Alveoli; ST Elevation Myocardial Infarction; Ticlopidine; Tomography, X-Ray Computed | 2016 |
Platelet reactivity in patients carrying the e-NOS G894T polymorphism after a loading dose of aspirin plus clopidogrel.
Topics: Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Humans; Nitric Oxide; Nitric Oxide Synthase Type III; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Ticlopidine | 2017 |
Dual Antiplatelet Therapy Does Not Increase the Risk of Bleeding After Carotid Endarterectomy: Results of a Prospective Study.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Asymptomatic Diseases; Carotid Stenosis; Clopidogrel; Drug Therapy, Combination; Endarterectomy, Carotid; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Prospective Studies; Risk Assessment; Risk Factors; Severity of Illness Index; Stroke; Ticlopidine; Time Factors; Treatment Outcome | 2017 |
Dipeptidyl Peptidase-4 Inhibitor-Associated Risk of Bleeding: An Evaluation of Reported Adverse Events.
Topics: Adverse Drug Reaction Reporting Systems; Aspirin; Clopidogrel; Dipeptidyl-Peptidase IV Inhibitors; Hemorrhage; Humans; Hypoglycemic Agents; Metformin; Odds Ratio; Platelet Aggregation Inhibitors; Retrospective Studies; Risk; Ticlopidine | 2017 |
Dual Antiplatelet Therapy and Clinical Outcomes after Coronary Drug-Eluting Stent Implantation in Patients on Hemodialysis.
Topics: Aged; Aspirin; Brain Ischemia; Case-Control Studies; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Humans; Kaplan-Meier Estimate; Kidney Failure, Chronic; Male; Middle Aged; Myocardial Infarction; Myocardial Revascularization; Platelet Aggregation Inhibitors; Propensity Score; Renal Dialysis; Retrospective Studies; Stroke; Survival Rate; Taiwan; Ticlopidine | 2017 |
Management of a Patient Requiring Intrathecal Drain Insertion and Removal in the Setting of Concomitant Dual Antiplatelet Therapy With Clopidogrel and Aspirin: A Case Report.
Topics: Aspirin; Catheters, Indwelling; Clopidogrel; Device Removal; Drainage; Drug Therapy, Combination; Endovascular Procedures; Hematoma, Epidural, Spinal; Humans; Hydrocephalus; Intracranial Aneurysm; Intracranial Thrombosis; Male; Metals; Middle Aged; Platelet Aggregation Inhibitors; Prosthesis Design; Risk Factors; Stents; Subarachnoid Hemorrhage; Ticlopidine; Treatment Outcome | 2017 |
Effect of antiplatelet therapy on aneurysmal sac expansion associated with type II endoleaks after endovascular aneurysm repair.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aortic Aneurysm, Abdominal; Aortography; Aspirin; Blood Vessel Prosthesis Implantation; Chi-Square Distribution; Clopidogrel; Computed Tomography Angiography; Contrast Media; Databases, Factual; Drug Therapy, Combination; Endoleak; Endovascular Procedures; Female; Humans; Kaplan-Meier Estimate; Male; Platelet Aggregation Inhibitors; Proportional Hazards Models; Retrospective Studies; Risk Assessment; Risk Factors; Spain; Ticlopidine; Time Factors; Treatment Outcome | 2017 |
Sex Differences in the Clinical Impact of High Platelet Reactivity After Percutaneous Coronary Intervention With Drug-Eluting Stents: Results From the ADAPT-DES Study (Assessment of Dual Antiplatelet Therapy With Drug-Eluting Stents).
Topics: Aged; Aspirin; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Resistance; Drug Therapy, Combination; Drug-Eluting Stents; Female; Germany; Hemorrhage; Humans; Kaplan-Meier Estimate; Logistic Models; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Propensity Score; Prospective Studies; Purinergic P2Y Receptor Antagonists; Registries; Risk Factors; Sex Factors; Ticlopidine; Time Factors; Treatment Outcome; United States | 2017 |
Aspirin desensitization in patients with coronary artery disease: Cost savings.
Topics: Aspirin; Clopidogrel; Coronary Disease; Cost Savings; Desensitization, Immunologic; Drug Hypersensitivity; Drug Substitution; Humans; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Salicylates; Ticlopidine | 2017 |
Letter by Moris et al Regarding Article, "Ticagrelor in Acute Stroke or Transient Ischemic Attack in Asian Patients: From the SOCRATES Trial (Acute Stroke or Transient Ischemic Attack Treated With Aspirin or Ticagrelor and Patient Outcomes)".
Topics: Adenosine; Aspirin; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Stroke; Ticagrelor; Ticlopidine | 2017 |
Response by Wang and Johnston to Letter Regarding Article, "Ticagrelor in Acute Stroke or Transient Ischemic Attack in Asian Patients: From the SOCRATES Trial (Acute Stroke or Transient Ischemic Attack Treated With Aspirin or Ticagrelor and Patient Outcom
Topics: Adenosine; Aspirin; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Stroke; Ticagrelor; Ticlopidine | 2017 |
The Effect of Combined Aspirin and Clopidogrel Treatment on Cancer Incidence.
Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Humans; Incidence; Male; Middle Aged; Neoplasms; Platelet Aggregation Inhibitors; Retrospective Studies; Ticlopidine | 2017 |
Reversible thrombotic mitral valve stenosis after transcatheter mitral valve replacement (TMVR): Is life-long anticoagulation therapy necessary?
Topics: Aged; Anticoagulants; Aspirin; Bioprosthesis; Cardiac Catheterization; Clopidogrel; Female; Heart Valve Prosthesis; Heart Valve Prosthesis Implantation; Humans; Mitral Valve; Mitral Valve Stenosis; Postoperative Complications; Thrombosis; Ticlopidine; Treatment Outcome; Warfarin | 2017 |
Clopidogrel-Paclitaxel Drug-Drug Interaction: A Pharmacoepidemiologic Study.
Topics: Aged; Aspirin; Clopidogrel; Cytochrome P-450 CYP2C8; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Liver; Male; Middle Aged; Paclitaxel; Peripheral Nervous System Diseases; Pharmacoepidemiology; Platelet Aggregation Inhibitors; Retrospective Studies; Severity of Illness Index; Ticlopidine | 2017 |
Platelet turnover predicts outcome after coronary intervention.
Topics: Aged; Aged, 80 and over; Aspirin; Biomarkers; Blood Platelets; Cell Adhesion Molecules; Chi-Square Distribution; Clopidogrel; Drug Therapy, Combination; Female; Hemorrhage; Humans; Kaplan-Meier Estimate; Linear Models; Logistic Models; Male; Mean Platelet Volume; Microfilament Proteins; Middle Aged; Multivariate Analysis; Odds Ratio; Percutaneous Coronary Intervention; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Purinergic P2Y Receptor Antagonists; Risk Factors; Stents; Ticlopidine; Time Factors; Treatment Outcome | 2017 |
Antiplatelet drug resistance did not increase the thromboembolic events after stent-assisted coiling of unruptured intracranial aneurysm: a single center experience of 99 cases.
Topics: Adult; Aged; Aspirin; Blood Vessel Prosthesis; Clopidogrel; Embolization, Therapeutic; Female; Humans; Intracranial Aneurysm; Magnetic Resonance Imaging; Male; Middle Aged; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2017 |
Improved Pig Model to Evaluate Heart Valve Thrombosis.
Topics: Animals; Aspirin; Blood Coagulation; Blood Platelets; Clopidogrel; Disease Models, Animal; Heart Valve Diseases; Heart Valve Prosthesis; Heart Valve Prosthesis Implantation; Humans; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Swine; Thrombosis; Ticlopidine | 2016 |
Association of Antithrombotic Drug Use With Subdural Hematoma Risk.
Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Case-Control Studies; Clopidogrel; Comorbidity; Denmark; Drug Therapy, Combination; Female; Fibrinolytic Agents; Hematoma, Subdural; Humans; Incidence; Male; Middle Aged; Odds Ratio; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine; Vitamin K; Young Adult | 2017 |
Mortality and cancer after 12 versus 30 months dual antiplatelet therapy. The Korean Outcomes Registry Evaluating Antithrombotics (KOREA).
Topics: Aged; Aspirin; Cause of Death; Chi-Square Distribution; Clopidogrel; Disease-Free Survival; Drug Administration Schedule; Drug Therapy, Combination; Female; Hemorrhage; Humans; Logistic Models; Male; Middle Aged; Neoplasms; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Propensity Score; Proportional Hazards Models; Registries; Republic of Korea; Retrospective Studies; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome | 2017 |
Clopidogrel, prasugrel, or ticagrelor use and clinical outcome in patients with acute coronary syndrome: A nationwide long-term registry analysis from 2009 to 2014.
Topics: Acute Coronary Syndrome; Adenosine; Aged; Aspirin; Austria; Clopidogrel; Drug Therapy, Combination; Female; Hospitalization; Humans; Incidence; Male; Medication Therapy Management; Patient Discharge; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Recurrence; Survival Analysis; Ticagrelor; Ticlopidine | 2017 |
A randomized clinical trial comparing long-term clopidogrel vs aspirin monotherapy beyond dual antiplatelet therapy after drug-eluting coronary stent implantation: Design and rationale of the Harmonizing Optimal Strategy for Treatment of coronary artery s
Topics: Acute Coronary Syndrome; Aspirin; Cause of Death; Clopidogrel; Coronary Stenosis; Drug Therapy, Combination; Drug-Eluting Stents; Hemorrhage; Humans; Mortality; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Time Factors; Treatment Outcome | 2017 |
Longer-term oral antiplatelet use in stable post-myocardial infarction patients: Insights from the long Term rIsk, clinical manaGement and healthcare Resource utilization of stable coronary artery dISease (TIGRIS) observational study.
Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Drug-Eluting Stents; Female; Humans; International Cooperation; Long Term Adverse Effects; Male; Middle Aged; Outcome Assessment, Health Care; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Risk Factors; ST Elevation Myocardial Infarction; Ticlopidine | 2017 |
State transition model: vorapaxar added to standard antiplatelet therapy to prevent thrombosis post myocardial infarction or peripheral artery disease.
Topics: Aspirin; Clopidogrel; Female; Hemorrhage; Humans; Lactones; Male; Middle Aged; Myocardial Infarction; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Pyridines; Quality of Life; Quality-Adjusted Life Years; Secondary Prevention; Stroke; Thrombosis; Ticlopidine | 2017 |
Association of genetic variant and platelet function in patients undergoing neuroendovascular stenting.
Topics: Adult; Aged; Aged, 80 and over; Alleles; Aspirin; Brain Ischemia; Clopidogrel; Female; Genetic Variation; Genotype; Humans; Linkage Disequilibrium; Male; Middle Aged; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Recurrence; Stents; Stroke; Thrombelastography; Ticlopidine | 2017 |
Platelet Reactivity and Clinical Outcomes After Coronary Artery Implantation of Drug-Eluting Stents in Subjects With Peripheral Arterial Disease: Analysis From the ADAPT-DES Study (Assessment of Dual Antiplatelet Therapy With Drug-Eluting Stents).
Topics: Aged; Aspirin; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Percutaneous Coronary Intervention; Peripheral Arterial Disease; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Propensity Score; Proportional Hazards Models; Prospective Studies; Purinergic P2Y Receptor Antagonists; Registries; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome | 2017 |
Kaposiform Hemangioendothelioma Presenting as Hydrops Fetalis.
Topics: Administration, Oral; Aspirin; Cesarean Section; Diagnosis, Differential; Drug Therapy, Combination; Follow-Up Studies; Gestational Age; Hemangioendothelioma; Humans; Hydrops Fetalis; Infant, Premature; Infusions, Intravenous; Kasabach-Merritt Syndrome; Magnetic Resonance Imaging; Male; Prednisone; Sarcoma, Kaposi; Ticlopidine; Treatment Outcome; Vincristine | 2017 |
Stent thrombosis in patients undergoing coronary stenting after return of spontaneous circulation. Does the choice of antiplatelet drug matter?
Topics: Aspirin; Coronary Thrombosis; Drug-Eluting Stents; Humans; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Treatment Outcome | 2017 |
The difference in association between aspirin use and other thrombocyte aggregation inhibitors and survival in patients with colorectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Colorectal Neoplasms; Dipyridamole; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Netherlands; Platelet Aggregation Inhibitors; Survival Analysis; Ticlopidine | 2017 |
Antithrombotic Activity of DAB-15, a Novel Diazepinobenzimidazole Compound.
Topics: Administration, Oral; Animals; Aspirin; Azepines; Benzimidazoles; Carotid Artery Thrombosis; Drug Evaluation, Preclinical; Fibrinolytic Agents; Male; Rats; Ticlopidine | 2017 |
Use of Aspirin and P2Y12 Response Assays in Detecting Reversal of Platelet Inhibition With Platelet Transfusion in Patients With Traumatic Brain Injury on Antiplatelet Therapy.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Platelets; Brain Injuries, Traumatic; Clopidogrel; Cohort Studies; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Transfusion; Receptors, Purinergic P2Y12; Ticlopidine | 2017 |
Utility of the Aspirin and P2Y12 Response Assays to Determine the Effect of Antiplatelet Agents on Platelet Reactivity in Traumatic Brain Injury.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Platelets; Brain Injuries, Traumatic; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Purinergic P2Y Receptor Antagonists; Ticlopidine | 2017 |
Letter by Taqueti and Bhatt Regarding Article, "Impact of Optimal Medical Therapy in the Dual Antiplatelet Therapy Study".
Topics: Aspirin; Drug Therapy, Combination; Platelet Aggregation Inhibitors; Ticlopidine | 2017 |
Response by Resor and Mauri to Letter Regarding Article, "Impact of Optimal Medical Therapy in the Dual Antiplatelet Therapy Study".
Topics: Aspirin; Drug Therapy, Combination; Platelet Aggregation Inhibitors; Ticlopidine | 2017 |
Short Communication: Evaluation of nephrotoxicity by aspirin-clopidogrel combination therapy in patients with acute coronary syndrome.
Topics: Acute Coronary Syndrome; Aspirin; Biomarkers; Blood Urea Nitrogen; Clopidogrel; Creatinine; Drug Therapy, Combination; Glomerular Filtration Rate; Humans; Kidney; Kidney Diseases; Platelet Aggregation Inhibitors; Risk Assessment; Ticlopidine; Time Factors; Treatment Outcome; Uric Acid | 2016 |
Malignant stroke in a ticagrelor non-responder as a complication following aneurysm treatment with the Pipeline Embolization Device™.
Topics: Adenosine; Aged; Aspirin; Carotid Artery, Internal; Cerebral Angiography; Clopidogrel; Embolization, Therapeutic; Female; Humans; Intracranial Aneurysm; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Stroke; Ticagrelor; Ticlopidine | 2017 |
Optimizing dual antiplatelet therapy duration after myocardial infarction: evidence-based, precision, or personalized medicine?
Topics: Aspirin; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Precision Medicine; Ticlopidine | 2017 |
Recommendations on the Clinical Use of Compound Danshen Dripping Pills.
Topics: Angina Pectoris; Aspirin; Camphanes; Clopidogrel; Coronary Disease; Diabetes Mellitus; Diabetic Nephropathies; Diabetic Retinopathy; Drugs, Chinese Herbal; Humans; Meta-Analysis as Topic; Panax notoginseng; Salvia miltiorrhiza; Ticlopidine | 2017 |
The association between high on-treatment platelet reactivity and early recurrence of ischemic events after minor stroke or TIA.
Topics: Adult; Aged; Aspirin; Blood Platelets; Clopidogrel; Cytochrome P-450 CYP2C19; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Prevalence; Prospective Studies; Recurrence; Stroke; Thrombelastography; Ticlopidine | 2017 |
Disaggregation Following Agonist-Induced Platelet Activation in Patients on Dual Antiplatelet Therapy.
Topics: Adenosine; Aged; Aspirin; Blood Platelets; Clopidogrel; Drug Monitoring; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Predictive Value of Tests; Reproducibility of Results; Signal Transduction; Stents; Ticagrelor; Ticlopidine; Treatment Outcome | 2017 |
Novel oral anticoagulants and trauma: The results of a prospective American Association for the Surgery of Trauma Multi-Institutional Trial.
Topics: Administration, Oral; Aged; Anticoagulants; Aspirin; Clopidogrel; Dabigatran; Female; Humans; Injury Severity Score; Intracranial Hemorrhages; Male; Platelet Aggregation Inhibitors; Prospective Studies; Pyrazoles; Pyridones; Rivaroxaban; Ticlopidine; Trauma Centers; Warfarin; Wounds and Injuries; Wounds, Nonpenetrating | 2017 |
Previous hypertensive hemorrhage increases the risk for bleeding and ischemia for PCI patients on dual antiplatelet therapy.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Case-Control Studies; Clopidogrel; Drug Therapy, Combination; Female; Hemorrhage; Humans; Ischemia; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Ticlopidine | 2017 |
Assessment of 'on-treatment platelet reactivity' and relationship with cerebral micro-embolic signals in asymptomatic and symptomatic carotid stenosis.
Topics: Aged; Aspirin; Brain; Carotid Stenosis; Case-Control Studies; Clopidogrel; Disease Progression; Female; Humans; Intracranial Embolism; Longitudinal Studies; Male; Middle Aged; Pilot Projects; Platelet Aggregation Inhibitors; Prevalence; Proof of Concept Study; Ticlopidine; Ultrasonography, Doppler, Transcranial | 2017 |
Vitamin D Binding Protein rs7041 polymorphism and high-residual platelet reactivity in patients receiving dual antiplatelet therapy with clopidogrel or ticagrelor.
Topics: Acute Coronary Syndrome; Adenosine; Aged; Aspirin; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Drug Resistance; Drug Therapy, Combination; Female; Gene Frequency; Genotype; Heterozygote; Homozygote; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Percutaneous Coronary Intervention; Pharmacogenetics; Pharmacogenomic Testing; Pharmacogenomic Variants; Phenotype; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Risk Factors; Ticagrelor; Ticlopidine; Treatment Outcome; Vitamin D Deficiency; Vitamin D-Binding Protein | 2017 |
Total Thrombus-formation Analysis System Predicts Periprocedural Bleeding Events in Patients With Coronary Artery Disease Undergoing Percutaneous Coronary Intervention.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Coagulation Tests; Clopidogrel; Coronary Artery Disease; Female; Hemorrhage; Humans; Intraoperative Complications; Male; Microchip Analytical Procedures; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Prasugrel Hydrochloride; Risk Assessment; Ticlopidine | 2017 |
The risk of lower gastrointestinal bleeding in low-dose aspirin users.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Clopidogrel; Comorbidity; Cyclooxygenase 2 Inhibitors; Databases, Factual; Dose-Response Relationship, Drug; Female; Gastrointestinal Hemorrhage; Histamine H2 Antagonists; Humans; Incidence; Male; Middle Aged; Peptic Ulcer; Peptic Ulcer Hemorrhage; Proton Pump Inhibitors; Renal Insufficiency, Chronic; Risk Factors; Selective Serotonin Reuptake Inhibitors; Taiwan; Ticlopidine; Warfarin; Young Adult | 2017 |
Outcome of Triple Antiplatelet Therapy Including Cilostazol in Elderly Patients with ST-Elevation Myocardial Infarction who Underwent Primary Percutaneous Coronary Intervention: Results from the INTERSTELLAR Registry.
Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Registries; Retrospective Studies; ST Elevation Myocardial Infarction; Tetrazoles; Ticlopidine | 2017 |
Review: After coronary DES, ≤ 6 mo and 1 y of dual-antiplatelet therapy do not differ for CV events at 1 y.
Topics: Aspirin; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2017 |
Potentially increased incidence of scaffold thrombosis in patients treated with Absorb BVS who terminated DAPT before 18 months.
Topics: Absorbable Implants; Aged; Aspirin; Cardiovascular Agents; Clopidogrel; Coated Materials, Biocompatible; Coronary Thrombosis; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Incidence; Male; Middle Aged; Netherlands; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prosthesis Design; Registries; Retrospective Studies; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome | 2017 |
Relationship Between Arterial Access and Outcomes in ST-Elevation Myocardial Infarction With a Pharmacoinvasive Versus Primary Percutaneous Coronary Intervention Strategy: Insights From the STrategic Reperfusion Early After Myocardial Infarction (STREAM)
Topics: Aged; Aspirin; Catheterization, Peripheral; Clopidogrel; Coronary Angiography; Enoxaparin; Female; Femoral Artery; Fibrinolytic Agents; Heart Failure; Hemorrhage; Humans; Male; Middle Aged; Mortality; Multivariate Analysis; Odds Ratio; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Radial Artery; Recurrence; Shock; ST Elevation Myocardial Infarction; Tenecteplase; Thrombolytic Therapy; Ticlopidine; Tissue Plasminogen Activator | 2016 |
Prevalence, Management, and Long-Term (6-Year) Outcomes of Atrial Fibrillation Among Patients Receiving Drug-Eluting Coronary Stents.
Topics: Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Female; Fibrinolytic Agents; Hemorrhage; Humans; Incidence; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Odds Ratio; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prevalence; Proportional Hazards Models; Republic of Korea; Risk Factors; Stroke; Ticlopidine; Time Factors; Treatment Outcome; Warfarin | 2017 |
Predicting long-term bleeding risk after acute coronary syndrome: a step closer to optimising dual antiplatelet therapy duration?
Topics: Acute Coronary Syndrome; Aspirin; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2017 |
Management of Kounis syndrome: two case reports.
Topics: Amoxicillin; Anaphylaxis; Anti-Inflammatory Agents; Anticoagulants; Aspirin; Chest Pain; Clopidogrel; Dexamethasone; Electrocardiography; Guidelines as Topic; Humans; Kounis Syndrome; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2017 |
Platelet distribution width as the prognostic marker in coronary bifurcation treatment.
Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Female; Humans; Male; Mean Platelet Volume; Middle Aged; Myocardial Revascularization; Non-ST Elevated Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Recurrence; Ticlopidine; Treatment Outcome | 2017 |
Impact of mean platelet aggregation degree on long-term clinical outcomes among patients undergoing a complex percutaneous coronary intervention.
Topics: Aged; Aspirin; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Proportional Hazards Models; Risk Factors; Stents; Ticlopidine; Time Factors; Treatment Outcome | 2017 |
Novel use of flow diversion for the treatment of aneurysms associated with arteriovenous malformations.
Topics: Adult; Arteriovenous Malformations; Aspirin; Clopidogrel; Embolization, Therapeutic; Female; Humans; Imaging, Three-Dimensional; Intracranial Aneurysm; Magnetic Resonance Angiography; Male; Middle Aged; Stents; Ticlopidine; Tomography Scanners, X-Ray Computed; Treatment Outcome | 2017 |
Platelet Function Testing in Patients with Acute Ischemic Stroke: An Observational Study.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Platelets; Brain Ischemia; Chi-Square Distribution; Clopidogrel; Cross-Sectional Studies; Cytochrome P-450 CYP2C19; Drug Resistance; Drug Therapy, Combination; Female; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Pharmacogenetics; Pharmacogenomic Testing; Pharmacogenomic Variants; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Genetic; Predictive Value of Tests; Risk Factors; Stroke; Ticlopidine; Treatment Outcome | 2017 |
Impact of platelet inhibition level on subsequent no-reflow in patients undergoing primary percutaneous coronary intervention for ST-segment elevation myocardial infarction.
Topics: Aged; Area Under Curve; Aspirin; Blood Platelets; Chi-Square Distribution; Clopidogrel; Coronary Angiography; Coronary Circulation; Drug Resistance; Female; Humans; Male; Microcirculation; Middle Aged; Multivariate Analysis; No-Reflow Phenomenon; Odds Ratio; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prospective Studies; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Risk Factors; ROC Curve; ST Elevation Myocardial Infarction; Ticlopidine; Time Factors; Treatment Outcome | 2017 |
Ischemic stroke complicating thrombolytic therapy with tenecteplase for ST elevation myocardial infarction: two case reports.
Topics: Aged; Aspirin; Clopidogrel; Electrocardiography; Fibrinolytic Agents; Heparin; Humans; Ischemic Attack, Transient; Male; Middle Aged; Percutaneous Coronary Intervention; ST Elevation Myocardial Infarction; Stents; Stroke; Tenecteplase; Ticlopidine; Tissue Plasminogen Activator; Treatment Outcome | 2017 |
Preventing graft restenosis after coronary artery bypass grafting with tissue-type plasminogen activator.
Topics: Aged; Aspirin; Blood Coagulation; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Female; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Prospective Studies; Ticlopidine; Tissue Plasminogen Activator; Treatment Outcome | 2017 |
Quantification of bleeding during dental extraction in patients on dual antiplatelet therapy.
Topics: Aspirin; Blood Loss, Surgical; Cardiovascular Diseases; Case-Control Studies; Clopidogrel; Dental Care for Chronically Ill; Female; Hemorrhage; Hemostasis, Surgical; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine; Tooth Extraction | 2017 |
Contemporary use of P2Y12-inhibitors in patients with acute coronary syndrome undergoing percutaneous coronary intervention in Austria: A prospective, multi-centre registry.
Topics: Acute Coronary Syndrome; Adenosine; Aged; Aspirin; Austria; Clopidogrel; Female; Hemorrhage; Hospital Mortality; Humans; Male; Middle Aged; Odds Ratio; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Prescription Drugs; Prospective Studies; Purinergic P2Y Receptor Antagonists; Registries; Ticagrelor; Ticlopidine | 2017 |
Platelet activation by crushed and uncrushed muscle: a flow cytometry analysis.
Topics: Aspirin; Clopidogrel; Flow Cytometry; Humans; Muscle, Skeletal; Platelet Activation; Platelet Aggregation Inhibitors; Ticlopidine | 2017 |
Do antiplatelet drugs increase the risk of bleeding after tooth extraction? A case-crossover study.
Topics: Aspirin; Cell Adhesion Molecules; Clopidogrel; Cross-Over Studies; Female; Flow Cytometry; Humans; Male; Microfilament Proteins; Middle Aged; Oral Hemorrhage; Phosphoproteins; Platelet Aggregation Inhibitors; Risk Assessment; Risk Factors; Ticlopidine; Tooth Extraction | 2017 |
Non-invasive management of post-partum spontaneous left main coronary artery dissection using cardiac computed tomography angiography.
Topics: Adult; Aspirin; Bisoprolol; Cesarean Section; Clopidogrel; Computed Tomography Angiography; Conservative Treatment; Coronary Angiography; Coronary Vessel Anomalies; Diagnosis, Differential; Drug Therapy, Combination; Electrocardiography; Female; Follow-Up Studies; Humans; Postpartum Period; Pregnancy; ST Elevation Myocardial Infarction; Ticlopidine; Treatment Outcome; Troponin T; Vascular Diseases | 2017 |
Cost-effectiveness analysis of 30-month vs 12-month dual antiplatelet therapy with clopidogrel and aspirin after drug-eluting stents in patients with acute coronary syndrome.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Computer Simulation; Coronary Thrombosis; Cost-Benefit Analysis; Decision Trees; Disease-Free Survival; Drug Administration Schedule; Drug Costs; Drug Therapy, Combination; Drug-Eluting Stents; Hemorrhage; Humans; Middle Aged; Models, Economic; Monte Carlo Method; Myocardial Infarction; Odds Ratio; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Quality-Adjusted Life Years; Risk Factors; Stroke; Ticlopidine; Time Factors; Treatment Outcome | 2017 |
Repetitive stent thrombosis in a patient with suspected allergy to aspirin and multiple switch between clopidogrel, prasugrel, and ticagrelor.
Topics: Adenosine; Aspirin; Clopidogrel; Coronary Vessels; Drug Hypersensitivity; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Recurrence; Stents; Thrombosis; Ticagrelor; Ticlopidine | 2017 |
Aspirin plus clopidogrel was not linked to risk for cancer compared with aspirin alone or no antiplatelets.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Neoplasms; Platelet Aggregation Inhibitors; Ticlopidine | 2017 |
Reply: Relevance of Indications for CABG in Evaluating the Effect of Dual Antiplatelet Therapy.
Topics: Aspirin; Coronary Artery Bypass; Platelet Aggregation Inhibitors; Ticlopidine | 2017 |
High On-Treatment Platelet Reactivity to Adenosine Diphosphate Predicts Ischemic Events of Minor Stroke and Transient Ischemic Attack.
Topics: Adenosine Diphosphate; Adult; Aged; Aspirin; Blood Platelets; Brain Ischemia; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Female; Humans; Ischemic Attack, Transient; Kaplan-Meier Estimate; Male; Middle Aged; Platelet Aggregation Inhibitors; Predictive Value of Tests; Prospective Studies; Recurrence; Risk Factors; Stroke; Thrombelastography; Ticlopidine; Time Factors; Treatment Outcome | 2017 |
Response to: "Aspirin Therapy on Blood Transfusion in Noncardiac Surgery: Evidence From Quality Effect Model".
Topics: Aspirin; Blood Transfusion; Clopidogrel; Platelet Aggregation Inhibitors; Ticlopidine | 2018 |
Quantifying Ischemic Risk After Percutaneous Coronary Intervention Attributable to High Platelet Reactivity on Clopidogrel (From the Assessment of Dual Antiplatelet Therapy with Drug-Eluting Stents Study).
Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug-Eluting Stents; Female; Germany; Graft Occlusion, Vascular; Humans; Incidence; Israel; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Activation; Platelet Aggregation Inhibitors; Prognosis; Prospective Studies; Quebec; Registries; Risk Assessment; Risk Factors; Survival Rate; Ticlopidine; United States | 2017 |
Aspirin Versus Clopidogrel for Type 2 Diabetic Patients with First-Ever Noncardioembolic Acute Ischemic Stroke: Ten-Year Survival Data from the Athens Stroke Outcome Project.
Topics: Aged; Aged, 80 and over; Aspirin; Brain Ischemia; Chi-Square Distribution; Clopidogrel; Diabetes Mellitus, Type 2; Female; Greece; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Patient Discharge; Platelet Aggregation Inhibitors; Proportional Hazards Models; Protective Factors; Recurrence; Retrospective Studies; Risk Factors; Secondary Prevention; Stroke; Ticlopidine; Time Factors; Treatment Outcome | 2017 |
Association between platelet function and recurrent ischemic vascular events after TIA and minor stroke
.
Topics: Alleles; Aspirin; Blood Coagulation Tests; Blood Platelets; Clopidogrel; Cytochrome P-450 CYP2C19; Female; Genotype; Humans; Ischemic Attack, Transient; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Recurrence; Stroke; Ticlopidine; Treatment Outcome | 2017 |
Effect of Dialysis on Antiplatelet Drug Efficacy in Uremic Patients with Coronary Heart Disease.
Topics: Aged; Aspirin; Clopidogrel; Coronary Disease; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Renal Dialysis; Thrombelastography; Ticlopidine; Uremia | 2017 |
Causes, Timing, and Impact of Dual Antiplatelet Therapy Interruption for Surgery (from the Patterns of Non-adherence to Anti-platelet Regimens In Stented Patients Registry).
Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Medication Adherence; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Preoperative Care; Prospective Studies; Registries; Retrospective Studies; Ticlopidine; Time Factors; Withholding Treatment | 2017 |
Impact of Aspirin and Clopidogrel Hyporesponsiveness in Patients Treated With Drug-Eluting Stents: 2-Year Results of a Prospective, Multicenter Registry Study.
Topics: Aged; Aspirin; Blood Platelets; Chi-Square Distribution; Clopidogrel; Coronary Thrombosis; Drug Resistance; Drug Therapy, Combination; Drug-Eluting Stents; Female; Germany; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Medication Adherence; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Function Tests; Proportional Hazards Models; Prospective Studies; Registries; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome; United States | 2017 |
The impact of CYP2C19*2, CYP4F2*3, and clinical factors on platelet aggregation, CYP4F2 enzyme activity, and 20-hydroxyeicosatetraenoic acid concentration in patients treated with dual antiplatelet therapy.
Topics: Adenosine; Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Cytochrome P-450 CYP2C19; Cytochrome P450 Family 4; Female; Humans; Hydroxyeicosatetraenoic Acids; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticagrelor; Ticlopidine | 2017 |
[Dual Antiplatelet Therapy in the Perioperative Period - To Continue or Discontinue Treatment?]
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Perioperative Period; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Ticlopidine | 2017 |
Aspirin Therapy on Blood Transfusion in Noncardiac Surgery: Evidence From Quality Effect Model.
Topics: Aspirin; Blood Transfusion; Clopidogrel; Platelet Aggregation Inhibitors; Ticlopidine | 2018 |
Emergent loading dose of antiplatelets for stenting after IV rt-PA in acute ischemic stroke: a feasibility study.
Topics: Administration, Intravenous; Aged; Aspirin; Brain Ischemia; Clopidogrel; Computed Tomography Angiography; Feasibility Studies; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Severity of Illness Index; Stents; Stroke; Ticlopidine; Tissue Plasminogen Activator; Tomography Scanners, X-Ray Computed; Treatment Outcome | 2018 |
Proton Pump Inhibitors may Reduce Bleeding Risk in Older Patients on Antiplatelet Therapy.
Topics: Aspirin; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Risk; Risk Factors; Ticlopidine | 2017 |
Too Hot? Too Cold? When Is it "Just Right" to Stop Dual Antiplatelet Therapy After PCI With DES?
Topics: Aspirin; Clopidogrel; Data Analysis; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2017 |
Which is the best antiaggregant or anticoagulant therapy after TAVI? A propensity-matched analysis from the ITER registry. The management of DAPT after TAVI.
Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Cohort Studies; Female; Hemorrhage; Humans; Male; Platelet Aggregation Inhibitors; Propensity Score; Registries; Stroke; Ticlopidine; Transcatheter Aortic Valve Replacement | 2017 |
Letter: bleeding in cirrhotics receiving coronary stenting and antiplatelet therapy.
Topics: Aspirin; Drug Therapy, Combination; Hemorrhage; Humans; Liver Cirrhosis; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2017 |
Letter: bleeding in cirrhotics receiving coronary stenting and antiplatelet therapy - author's reply.
Topics: Aspirin; Drug Therapy, Combination; Hemorrhage; Humans; Liver Cirrhosis; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2017 |
Response by Lee and Ovbiagele to Letter Regarding Article, "Antiplatelet Regimen for Patients With Breakthrough Strokes While on Aspirin: A Systematic Review and Meta-Analysis".
Topics: Aspirin; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2017 |
Letter by Spence Regarding Article, "Antiplatelet Regimen for Patients With Breakthrough Strokes While on Aspirin: A Systematic Review and Meta-Analysis".
Topics: Aspirin; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2017 |
Triple therapy with dual antiplatelet treatment and direct oral anticoagulants. Author's reply.
Topics: Administration, Oral; Anticoagulants; Aspirin; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2018 |
The efficacy and safety of cilostazol as an alternative to aspirin in Chinese patients with aspirin intolerance after coronary stent implantation: a combined clinical study and computational system pharmacology analysis.
Topics: Aged; Asian People; Aspirin; China; Cilostazol; Clopidogrel; Coronary Restenosis; Data Interpretation, Statistical; Drug Combinations; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Molecular Docking Simulation; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Retrospective Studies; Tetrazoles; Ticlopidine | 2018 |
Safety and Necessity of Antiplatelet Therapy on Patients Underwent Endovascular Aortic Repair with Both Stanford Type B Aortic Dissection and Coronary Heart Disease.
Topics: Adult; Aged; Aspirin; Clopidogrel; Coronary Angiography; Coronary Disease; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Ticlopidine | 2017 |
Risk stratification with the DAPT score: Carefully read the instructions and use as intended.
Topics: Aspirin; Drug Therapy, Combination; Drug-Eluting Stents; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticlopidine | 2017 |
In PCI-treated ACS, switching from aspirin + a newer P2Y12 blocker to aspirin + clopidogrel reduced adverse events.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2017 |
Risky business? Investigating outcomes of patients undergoing urgent laparoscopic appendectomy on antithrombotic therapy.
Topics: Adult; Appendectomy; Appendicitis; Aspirin; Blood Loss, Surgical; Blood Transfusion; Clopidogrel; Female; Fibrinolytic Agents; Humans; Laparoscopy; Length of Stay; Male; Middle Aged; Patient Readmission; Platelet Aggregation Inhibitors; Postoperative Complications; Retrospective Studies; Surgical Wound Infection; Ticlopidine; Treatment Outcome; United States | 2017 |
Superior safety of dual therapy with dabigatran and clopidogrel vs. triple therapy with warfarin, aspirin and clopidogrel in the RE-DUAL PCI trial: What is key, the strategy or the drug?
Topics: Aspirin; Clopidogrel; Dabigatran; Drug Therapy, Combination; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome; Warfarin | 2017 |
Isolated left ventricular non-compaction (LVNC) and recurrent strokes: to anticoagulate or not to anticoagulate, that is the question.
Topics: Aged; Anticoagulants; Aspirin; Clopidogrel; Diagnosis, Differential; Humans; Isolated Noncompaction of the Ventricular Myocardium; Magnetic Resonance Imaging; Male; Recurrence; Stroke; Ticlopidine | 2017 |
Outcome of Transurethral Resection of Bladder Tumor: Does Antiplatelet Therapy Really Matter? Analysis of a Retrospective Series.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Carcinoma, Transitional Cell; Clopidogrel; Cystoscopy; Female; Hemorrhage; Humans; Intraoperative Complications; Length of Stay; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Ticlopidine; Urinary Bladder Neoplasms; Urologic Surgical Procedures | 2017 |
Impaired liver cytochrome P450 2C11 activity after dual antiplatelet therapy with aspirin and clopidogrel in rats.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Aspirin; Chromatography, Liquid; Clopidogrel; Cytochrome P450 Family 2; Inactivation, Metabolic; Liver; Male; Platelet Aggregation Inhibitors; Rats, Sprague-Dawley; Salicylic Acid; Steroid 16-alpha-Hydroxylase; Tandem Mass Spectrometry; Ticlopidine | 2018 |
Dual Antiplatelet Therapy Duration in Conservatively Managed Patients with Acute Coronary Syndrome: Any News?
Topics: Acute Coronary Syndrome; Aspirin; Drug Therapy, Combination; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticlopidine | 2017 |
Portal vein thrombosis before and after transjugular intrahepatic portosystemic shunt placement: An observational study (STROBE compliant).
Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Clopidogrel; Female; Humans; Leukocyte Count; Liver Cirrhosis; Male; Middle Aged; Portal Vein; Portasystemic Shunt, Transjugular Intrahepatic; Prospective Studies; Risk Factors; Severity of Illness Index; Ticlopidine; Venous Thrombosis; Warfarin | 2017 |
Dual antiplatelet therapy after acute coronary syndromes: no time for a CHANGE.
Topics: Acute Coronary Syndrome; Aspirin; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2017 |
Clopidogrel or ticagrelor in acute coronary syndrome patients treated with newer-generation drug-eluting stents: CHANGE DAPT.
Topics: Acute Coronary Syndrome; Adenosine; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticagrelor; Ticlopidine | 2017 |
Decreased platelet inhibition by P2Y12 receptor blockers in anaemia.
Topics: Adenosine; Adenosine Diphosphate; Aged; Anemia; Angioplasty; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Monocytes; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Stents; Ticagrelor; Ticlopidine | 2018 |
Clinical characteristics and outcomes of patients with coronary artery spasm who initially presented with acute myocardial infarction.
Topics: Adult; Aged; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Cardiovascular Diseases; Case-Control Studies; Clopidogrel; Coronary Vasospasm; Female; Follow-Up Studies; Humans; Incidence; Logistic Models; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prognosis; Propensity Score; Proportional Hazards Models; Recurrence; Retrospective Studies; Ticlopidine | 2018 |
[Clinical effectiveness and safety of ticagrelor in patients after PCI because of acute non ST segment elevation myocardial infarction].
Topics: Adenosine; Aspirin; China; Humans; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Thrombolytic Therapy; Ticagrelor; Ticlopidine; Treatment Outcome | 2017 |
Risk factors for postpolypectomy bleeding in patients receiving anticoagulation or antiplatelet medications.
Topics: Aged; Anticoagulants; Aspirin; Case-Control Studies; Clopidogrel; Colonic Polyps; Colonoscopy; Colorectal Neoplasms; Female; Gastrointestinal Hemorrhage; Heparin, Low-Molecular-Weight; Humans; Incidence; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Retrospective Studies; Risk Factors; Thromboembolism; Ticlopidine; Time Factors; Warfarin | 2018 |
Platelet function monitoring for stent thrombosis in critically III patients with an acute Coronary syndrome.
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Retrospective Studies; Risk Factors; Stents; Thrombosis; Ticlopidine | 2018 |
Impact of Proton-pump Inhibitors on the Pharmacodynamic Effect and Clinical Outcomes in Patients Receiving Dual Antiplatelet Therapy after Percutaneous Coronary Intervention: A Propensity Score Analysis.
Topics: Adenosine Diphosphate; Aged; Aspirin; Clopidogrel; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Proton Pump Inhibitors; Thrombelastography; Ticlopidine | 2017 |
Perioperative Management of Dual Antiplatelet Therapy.
Topics: Aspirin; Elective Surgical Procedures; Hemorrhage; Humans; Perioperative Care; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine; Tirofiban; Tyrosine | 2018 |
STARTING-SICH Nomogram to Predict Symptomatic Intracerebral Hemorrhage After Intravenous Thrombolysis for Stroke.
Topics: Aged; Aged, 80 and over; Aspirin; Brain Ischemia; Cerebral Hemorrhage; Clopidogrel; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Nomograms; Risk Factors; Stroke; Thrombolytic Therapy; Ticlopidine; Tissue Plasminogen Activator | 2018 |
Etiology of gastrointestinal bleeding in patients on dual antiplatelet therapy.
Topics: Aged; Aspirin; Clopidogrel; Drug Therapy, Combination; Endoscopy, Gastrointestinal; Esophageal and Gastric Varices; Female; Gastroenteritis; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Retrospective Studies; Risk Factors; Severity of Illness Index; Ticlopidine | 2018 |
Gastrointestinal protection with dual antiplatelet therapies.
Topics: Aspirin; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2018 |
Which Antiplatelet Therapy in Patients With Left Ventricular Assist Device and Aspirin Allergy?
Topics: Aspirin; Clopidogrel; Drug Hypersensitivity; Drug Therapy, Combination; Heart Failure; Heart-Assist Devices; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Thrombosis; Ticlopidine; Warfarin | 2018 |
WATCHMAN device-related thrombus successfully treated with apixaban: A case report.
Topics: Aged; Anticoagulants; Aspirin; Atrial Appendage; Atrial Fibrillation; Clopidogrel; Factor Xa Inhibitors; Humans; Male; Prostheses and Implants; Pyrazoles; Pyridones; Thrombosis; Ticlopidine | 2017 |
A Difference in Bleeding and Use of Blood and Blood Products in Patients who Were Preoperatively on Aspirin or Dual Antiplatelet Therapy Before Coronary Artery Bypass Grafting.
Topics: Aged; Aspirin; Blood Transfusion; Clopidogrel; Coronary Artery Bypass; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Preoperative Care; Retrospective Studies; Ticlopidine | 2018 |
Basilar artery fenestration: an unusual possible cause of ischaemic stroke?
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Ataxia; Basilar Artery; Cerebral Angiography; Clopidogrel; Humans; Magnetic Resonance Imaging; Male; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Treatment Outcome; Vertebrobasilar Insufficiency; Vertigo; Vomiting | 2018 |
Reversal of antiplatelet therapy in traumatic intracranial hemorrhage: Does timing matter?
Topics: Adult; Aged; Aspirin; Clopidogrel; Female; Glasgow Coma Scale; Hematoma, Subdural; Humans; Intracranial Hemorrhage, Traumatic; Middle Aged; Platelet Aggregation Inhibitors; Platelet Transfusion; Retrospective Studies; Risk Factors; Ticlopidine; Time Factors | 2018 |
Self-Reported Headaches in Patients with Unruptured Intracranial Aneurysms Treated with the Pipeline Embolization Device.
Topics: Adult; Aged; Aged, 80 and over; Angiography, Digital Subtraction; Aspirin; Clopidogrel; Comorbidity; Embolization, Therapeutic; Female; Headache Disorders, Secondary; Humans; Intracranial Aneurysm; Magnetic Resonance Angiography; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Self Report; Single-Blind Method; Surveys and Questionnaires; Ticlopidine; Treatment Outcome | 2018 |
The Prognostic Value of Combinations of Genetic Polymorphisms in the ITGB3, ITGA2, and CYP2C19*2 Genes in Predicting Cardiovascular Outcomes After Coronary Bypass Grafting.
Topics: Aged; Alleles; Angina Pectoris; Aspirin; Clopidogrel; Combined Modality Therapy; Coronary Artery Bypass; Cytochrome P-450 CYP2C19; Humans; Integrin alpha2; Integrin beta3; Middle Aged; Mutation; Platelet Aggregation; Polymorphism, Single Nucleotide; Prognosis; Real-Time Polymerase Chain Reaction; Ticlopidine; Treatment Outcome | 2018 |
A clinical risk score to identify patients at high risk of very late stent thrombosis.
Topics: Aspirin; Case-Control Studies; Female; Hemorrhage; Humans; Long Term Adverse Effects; Male; Middle Aged; Myocardial Infarction; Netherlands; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prognosis; Risk Assessment; Risk Factors; Stents; Thrombosis; Ticlopidine | 2018 |
Gene polymorphisms in dual antiplatelet therapy and the presence of hypo-attenuated leaflet thickening after transcatheter aortic valve replacement.
Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Resistance; Female; Heart Valve Prosthesis; Humans; Male; Pilot Projects; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Prospective Studies; Ticlopidine; Transcatheter Aortic Valve Replacement | 2018 |
Compression force sensing regulates integrin α
Topics: Adult; Animals; Aspirin; Blood Platelets; Clopidogrel; Diabetes Mellitus, Type 1; Female; Humans; Male; Mice; Mice, Inbred C57BL; Middle Aged; Phosphatidylinositol 3-Kinases; Platelet Adhesiveness; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombosis; Ticlopidine | 2018 |
12 months of DAPT after acute coronary syndrome still beats 6 months.
Topics: Acute Coronary Syndrome; Aspirin; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticlopidine | 2018 |
Is proton pump inhibitors' prophylaxis indicated for patients on antiplatelet therapy?
Topics: Aspirin; Drug Interactions; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine | 2018 |
Letter by Henni et al Regarding Article, "Aspirin Monotherapy Should Not Be Recommended for Cardioprotection in Patients With Symptomatic Peripheral Artery Disease".
Topics: Aspirin; Humans; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Ticlopidine | 2018 |
Optimal antiplatelet therapy after an acute coronary syndrome in the elderly: An old issue.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2018 |
Panax quinquefolius saponins combined with dual antiplatelet drug therapy alleviate gastric mucosal injury and thrombogenesis through the COX/PG pathway in a rat model of acute myocardial infarction.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Platelets; Clopidogrel; Cyclooxygenase 2; Gastric Mucosa; Male; Myocardial Infarction; Myocardium; Panax; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Saponins; Thromboxane B2; Ticlopidine; Tissue Plasminogen Activator; Vascular Endothelial Growth Factor A | 2018 |
Artery of Percheron: an unusual stroke presentation.
Topics: Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Aspirin; Atorvastatin; Cerebral Arteries; Clopidogrel; Diagnosis, Differential; Female; Humans; Magnetic Resonance Imaging; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Vascular Malformations | 2018 |
Single and dual antiplatelet therapy in elderly patients of medically managed myocardial infarction.
Topics: Aged, 80 and over; Aspirin; Cause of Death; Clopidogrel; Drug Therapy, Combination; Electrocardiography; Female; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; ST Elevation Myocardial Infarction; Taiwan; Ticlopidine; Time Factors; Treatment Outcome | 2018 |
DEVELOPMENT OF COMPRESSED COATED POLYPILL WITH MUCOADHESIVE CORE COMPRISING OF ATORVASTATIN/CLOPIDOGREL/ASPIRIN USING COMPRESSION COATING TECHNIQUE.
Topics: Acrylates; Adhesiveness; Administration, Oral; Animals; Aspirin; Atorvastatin; Carboxymethylcellulose Sodium; Chemistry, Pharmaceutical; Clopidogrel; Delayed-Action Preparations; Drug Combinations; Drug Compounding; Drug Liberation; Hydrogen-Ion Concentration; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypromellose Derivatives; Intestinal Mucosa; Kinetics; Models, Chemical; Platelet Aggregation Inhibitors; Polymers; Polypharmacy; Rabbits; Solubility; Surface Properties; Tablets, Enteric-Coated; Technology, Pharmaceutical; Ticlopidine | 2017 |
To the Editor: Perioperative interruption of dual antiplatelet therapy.
Topics: Aspirin; Drug Therapy, Combination; Humans; Perioperative Care; Platelet Aggregation Inhibitors; Ticlopidine | 2018 |
In reply: Perioperative interruption of dual antiplatelet therapy.
Topics: Aspirin; Drug Therapy, Combination; Humans; Perioperative Care; Platelet Aggregation Inhibitors; Ticlopidine | 2018 |
Do practice gaps exist in evidence-based medication prescription at hospital discharge in patients undergoing coronary artery bypass surgery & coronary angioplasty?
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angioplasty; Angioplasty, Balloon, Coronary; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Coronary Vessels; Drug Prescriptions; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; India; Male; Middle Aged; Percutaneous Coronary Intervention; Professional Practice Gaps; Retrospective Studies; Ticlopidine | 2017 |
Review: Adding clopidogrel to ASA reduces CV morbidity but increases bleeding in patients at high risk for CV events.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2018 |
Anterior spinal cord infarct: a rare yet disabling stroke.
Topics: Aged, 80 and over; Aspirin; Atorvastatin; Clopidogrel; Diagnosis, Differential; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Male; Platelet Aggregation Inhibitors; Rare Diseases; Spinal Cord; Spinal Cord Ischemia; Stroke; Stroke Rehabilitation; Ticlopidine; Treatment Outcome | 2018 |
[High On-Treatment Platelet Reactivity Determinants on Dual Antiplatelet Therapy in Patients With Ischemic Heart Disease Before Elective Percutaneous Coronary Intervention].
Topics: Aged; Aspirin; Blood Platelets; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Humans; Middle Aged; Myocardial Ischemia; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2018 |
Prevention of recurrent venous thrombosis and post-thrombotic syndrome.
Topics: Aspirin; Drug Therapy, Combination; Female; Fibrinolytic Agents; Flavonoids; Glycosaminoglycans; Humans; Incidence; Male; Middle Aged; Plant Extracts; Platelet Aggregation Inhibitors; Postthrombotic Syndrome; Recurrence; Registries; Retrospective Studies; Ticlopidine; Venous Thrombosis | 2018 |
Dual therapy with clopidogrel and aspirin prevents early neurological deterioration in ischemic stroke patients carrying CYP2C19*2 reduced-function alleles.
Topics: Aged; Aged, 80 and over; Aspirin; Brain Ischemia; China; Clinical Decision-Making; Clopidogrel; Cytochrome P-450 CYP2C19; Disease Progression; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Pharmacogenomic Variants; Platelet Aggregation; Platelet Aggregation Inhibitors; Precision Medicine; Prospective Studies; Stroke; Ticlopidine; Treatment Outcome | 2018 |
Clinical Significance of Acute and Serial Platelet Function Testing in Acute Ischemic Stroke.
Topics: Acute Disease; Aged; Aspirin; Blood Platelets; Brain Ischemia; Clopidogrel; Female; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prognosis; Prospective Studies; Ticlopidine | 2018 |
Peripheral artery disease: How do genes and pharmacology interplay?
Topics: Aspirin; Clopidogrel; Humans; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Ticlopidine | 2018 |
Efficacy and safety of CYP2C19 genotype in stroke or transient ischemic attack patients treated with clopidogrel monotherapy or clopidogrel plus aspirin: Protocol for a systemic review and meta-analysis.
Topics: Aspirin; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Genotype; Humans; Ischemic Attack, Transient; Meta-Analysis as Topic; Platelet Aggregation Inhibitors; Stroke; Systematic Reviews as Topic; Ticlopidine; Treatment Outcome | 2018 |
Effect of Physical Exercise on Platelet Reactivity in Patients with Dual Antiplatelet Therapy.
Topics: Adenosine Diphosphate; Aspirin; Chromogranin A; Clopidogrel; Coronary Artery Disease; Electrocardiography; Exercise; Exercise Tolerance; Humans; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Count; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Stents; Thrombosis; Ticlopidine | 2018 |
Evidences about combination use of acetylsalicylic acid (aspirin) and clopidogrel in acute coronary syndrome.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2017 |
Cessation of dual antiplatelet therapy and cardiovascular events following acute coronary syndrome.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Cardiovascular Diseases; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prognosis; Retrospective Studies; Risk Assessment; Scotland; Stroke; Ticlopidine; Time Factors; Withholding Treatment | 2019 |
Bleeding after stenting: statistics in daily practice.
Topics: Aspirin; Drug Therapy, Combination; Drug-Eluting Stents; Hemorrhage; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Treatment Outcome | 2018 |
Aspirin Plus Clopidogrel vs Aspirin Alone for Preventing Cardiovascular Events Among Patients at High Risk for Cardiovascular Events.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Review Literature as Topic; Stroke; Ticlopidine | 2018 |
Comparison of factors affecting platelet reactivity in various platelet function tests.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Clopidogrel; Cross-Sectional Studies; Female; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Ticlopidine | 2019 |
Two common mutations within CYP2C19 affected platelet aggregation in Chinese patients undergoing PCI: a one-year follow-up study.
Topics: Alleles; Aspirin; Blood Platelets; China; Cytochrome P-450 CYP2C19; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Haplotypes; Humans; Loss of Function Mutation; Male; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Ticlopidine | 2019 |
Interaction study between antiplatelet agents, anticoagulants, thyroid replacement therapy and a bioavailable formulation of curcumin (Meriva®).
Topics: Anticoagulants; Aspirin; Blood Glucose; Clopidogrel; Curcumin; Drug Compounding; Drug Interactions; Female; Glycated Hemoglobin; Humans; Male; Middle Aged; Osteoarthritis; Platelet Aggregation Inhibitors; Thyroxine; Ticlopidine; Warfarin | 2018 |
The safety of triple antiplatelet therapy under thromboelastography guidance in patients undergoing stenting for ischemic cerebrovascular disease.
Topics: Aged; Aspirin; Brain Ischemia; Cilostazol; Clopidogrel; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Stents; Stroke; Thrombelastography; Ticlopidine | 2019 |
Aspirin-still the GLOBAL LEADER in antiplatelet therapy.
Topics: Aspirin; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2018 |
Effectiveness of Platelet Function Analyzer-100 for Laboratory Detection of Anti-Platelet Drug-Induced Platelet Dysfunction.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Child; Child, Preschool; Clopidogrel; Female; Humans; Infant; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine; Young Adult | 2019 |
How to select antiplatelet therapy in patients with acute coronary syndrome, according to platelet function testing or pharmacogenomic testing?
Topics: Acute Coronary Syndrome; Aspirin; Blood Platelets; Drug Therapy, Combination; Humans; Percutaneous Coronary Intervention; Pharmacogenomic Testing; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Ticlopidine | 2018 |
Response to Letter of Li et al.: How to select antiplatelet therapy in patients with acute coronary syndrome, according to platelet function testing or pharmacogenomic testing?
Topics: Acute Coronary Syndrome; Aspirin; Blood Platelets; Drug Therapy, Combination; Humans; Pharmacogenomic Testing; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Ticlopidine | 2018 |
Laboratory monitoring of P2Y
Topics: Acute Coronary Syndrome; Anticoagulants; Aspirin; Blood Coagulation; Cardiology; Clopidogrel; Genetic Variation; Humans; International Cooperation; Monitoring, Physiologic; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Societies, Medical; Ticlopidine | 2018 |
Regarding "A systematic review of the efficacy of aspirin monotherapy versus other antiplatelet therapy regimens in peripheral arterial disease".
Topics: Aspirin; Humans; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Ticlopidine | 2018 |
Impact of dual antiplatelet therapy with adjusted-dose prasugrel on mid-term vascular response in patients undergoing elective percutaneous coronary intervention with everolimus-eluting stents.
Topics: Aged; Aged, 80 and over; Aspirin; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug-Eluting Stents; Everolimus; Female; Humans; Japan; Logistic Models; Male; Middle Aged; Multivariate Analysis; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Postoperative Complications; Prasugrel Hydrochloride; Prospective Studies; Thrombosis; Ticlopidine; Tomography, Optical Coherence | 2019 |
The clinical dilemma of managing patients who are on dual antiplatelet therapy and require major non-cardiac surgery.
Topics: Anesthesia; Aspirin; Drug Therapy, Combination; Humans; Patient Care Management; Perioperative Care; Platelet Aggregation Inhibitors; Propensity Score; Surgical Procedures, Operative; Ticlopidine | 2019 |
High On-Treatment Platelet Reactivity Determinants on Dual Antiplatelet Therapy in Patients With Ischemic Heart Disease Before Elective Percutaneous Coronary Intervention.
Topics: Aged; Aspirin; Blood Platelets; Cytochrome P-450 CYP2C19; Humans; Middle Aged; Myocardial Ischemia; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2018 |
New opportunities to optimize antithrombotic therapy for secondary stroke prevention.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Secondary Prevention; Stroke; Ticagrelor; Ticlopidine; Treatment Outcome | 2019 |
[Impact of discontinuation of aspirin and clopidogrel before off-pump coronary artery bypass grafting on postoperative bleeding and transfusion requirement].
Topics: Aged; Aspirin; Blood Transfusion; Clopidogrel; Coronary Artery Bypass; Female; Humans; Male; Middle Aged; Postoperative Hemorrhage; Retrospective Studies; Ticlopidine | 2019 |
Omission of aspirin after ACS or stenting in patients with oral anticoagulation - why have the goalposts moved?
Topics: Administration, Oral; Anticoagulants; Aspirin; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2019 |
Recurrent retinal vein thrombosis: prevention with Aspirin, Pycnogenol®, ticlopidine, or sulodexide.
Topics: Adult; Aspirin; Female; Fibrinolytic Agents; Flavonoids; Glycosaminoglycans; Humans; Incidence; Male; Middle Aged; Plant Extracts; Platelet Aggregation Inhibitors; Recurrence; Registries; Retinal Vein Occlusion; Retrospective Studies; Risk Factors; Ticlopidine | 2019 |
PURL: Should you switch the DAPT agent one month after ACS?
Topics: Acute Coronary Syndrome; Aspirin; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2019 |
Efficacy of Antiplatelet Agent Usage for Primary and Secondary Prevention in Dialysis Patients: a Nationwide Data Survey and Propensity Analysis.
Topics: Aspirin; Clopidogrel; Cohort Studies; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Primary Prevention; Renal Dialysis; Secondary Prevention; Stroke; Surveys and Questionnaires; Ticlopidine | 2019 |
Short-term Safety and Mid-term Efficacy of Prasugrel Versus Clopidogrel in Patients Undergoing Percutaneous Coronary Intervention.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Retrospective Studies; Ticlopidine | 2019 |
Adherence to Antiplatelet Therapy after Coronary Intervention among Patients with Myocardial Infarction Attending Vietnam National Heart Institute.
Topics: Adult; Aspirin; Clopidogrel; Cross-Sectional Studies; Female; Heart; Humans; Income; Male; Medication Adherence; Middle Aged; Multivariate Analysis; Myocardial Infarction; Patient Discharge; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Regression Analysis; Surveys and Questionnaires; Ticlopidine; Vietnam | 2019 |
Dual Antiplatelet Therapy: Is It Time to Cut the Cord With Aspirin?
Topics: Aspirin; Clopidogrel; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticlopidine | 2019 |
Hematoma of Sternocleidomastoid Aspirin can be a Cause.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Hematoma; Humans; Neck Muscles; Platelet Aggregation Inhibitors; Ticlopidine | 2019 |
The effect of esomeprazole vs famotidine on aspirin/clopidogrel dual therapy after percutaneous coronary intervention.
Topics: Aspirin; Blood Platelets; Clopidogrel; Drug Therapy, Combination; Esomeprazole; Famotidine; Humans; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine; Treatment Outcome | 2019 |
CSPS.com Trial of Adding Cilostazol to Antiplatelet Therapy to Reduce Recurrent Stroke.
Topics: Aspirin; Cerebral Infarction; Cilostazol; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Recurrence; Stroke; Ticlopidine | 2020 |
Aspirin plus clopidogrel versus aspirin Mono-Therapy for ischemic stroke.
Topics: Aspirin; Brain Ischemia; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine | 2020 |
Gender Differences in Platelet Reactivity in Diabetic Patients Receiving Dual Antiplatelet Therapy.
Topics: Adenosine; Aftercare; Aspirin; Blood Platelets; Diabetes Mellitus; Drug Therapy, Combination; Female; Humans; Male; Patient Discharge; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Sex Characteristics; Ticlopidine | 2020 |
Aspirin alone is safer than dual antiplatelet therapy in patients undergoing TAVI.
Topics: Aspirin; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Transcatheter Aortic Valve Replacement | 2020 |
Aspirin Monotherapy vs. DAPT after TAVI: Is Less More? Comment on the POPular TAVI Trial.
Topics: Aspirin; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Transcatheter Aortic Valve Replacement | 2020 |
Effect of bodyweight on VerifyNow Aspirin platelet function test: a retrospective review.
Topics: Aspirin; Blood Platelets; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Retrospective Studies; Ticlopidine | 2021 |
Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers in Acute Coronary Syndrome: Implications for Platelet Reactivity?
Topics: Acute Coronary Syndrome; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Clopidogrel; Dual Anti-Platelet Therapy; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Function Tests; Ticlopidine | 2021 |
Efficacy of aspirin, clopidogrel, and ticlopidine in stroke prevention: A population-based case-cohort study in Taiwan.
Topics: Adult; Aged; Aspirin; Brain Ischemia; Clopidogrel; Cohort Studies; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Propensity Score; Recurrence; Secondary Prevention; Stroke; Taiwan; Ticlopidine | 2020 |
MORPHOLOGICAL CHANGES OF THE GASTRIC MUCOSA WHILE USING ANTIAGGREGANTS AND PANTOPRAZOLE (AN EXPERIMENTAL STUDY).
Topics: Animals; Aspirin; Clopidogrel; Gastric Mucosa; Male; Pantoprazole; Rats; Ticlopidine | 2021 |
Stronger inhibitory effects of Ticagrelor plus aspirin compared with Clopidogrel plus aspirin on arachidonic acid-induced platelet aggregation in patients with acute coronary syndrome with PCI.
Topics: Acute Coronary Syndrome; Adenosine; Arachidonic Acid; Aspirin; Clopidogrel; Humans; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Ticagrelor; Ticlopidine; Treatment Outcome | 2021 |
Cell-based high-throughput screening for the evaluation of reactive metabolite formation potential.
Topics: Activation, Metabolic; Aspirin; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Coculture Techniques; Cytochrome P-450 Enzyme System; Diclofenac; Glutathione; Hepatocytes; High-Throughput Screening Assays; Humans; Microsomes, Liver; Ticlopidine | 2021 |
Spontaneous spinal epidural hematoma associated with antiplatelet therapy with aspirin and ticagrelor.
Topics: Aspirin; Hematoma, Epidural, Spinal; Humans; Platelet Aggregation Inhibitors; Ticagrelor; Ticlopidine | 2021 |
Letter to the Editor: How Should We Treat High-risk Patients in the Chronic Phase Following PCI: Clopidogrel or Prolonged DAPT?
Topics: Aspirin; Clopidogrel; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticlopidine | 2021 |
Challenging the Role of Aspirin for Long-Term Antiplatelet Therapy?
Topics: Aspirin; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Ticlopidine | 2021 |
Balancing Benefits and Risks of Long-Term Antiplatelet Therapy in Noncardioembolic Transient Ischemic Attack or Stroke.
Topics: Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; Intracranial Hemorrhages; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Recurrence; Risk Assessment; Stroke; Ticlopidine; Treatment Outcome | 2021 |
The comparison between the effects of aspirin and clopidogrel monotherapy on postoperative bleeding in diabetic patients after off-pump coronary artery bypass surgery.
Topics: Aspirin; Clopidogrel; Coronary Artery Bypass, Off-Pump; Diabetes Mellitus; Humans; Platelet Aggregation Inhibitors; Retrospective Studies; Ticlopidine | 2021 |
Utility of a pharmacogenetic-driven algorithm in guiding dual antiplatelet therapy for patients undergoing coronary drug-eluting stent implantation in China.
Topics: Aged; Algorithms; Asian People; Aspirin; Cardiovascular Diseases; China; Clopidogrel; Comorbidity; Cytochrome P-450 CYP2C19; Drug-Eluting Stents; Dual Anti-Platelet Therapy; Female; Health Behavior; Hemorrhage; Humans; Male; Middle Aged; Pharmacogenetics; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Risk Assessment; Risk Factors; Sociodemographic Factors; Ticagrelor; Ticlopidine | 2022 |
Dual Antiplatelet Therapy Plus Argatroban Prevents Early Neurological Deterioration in Branch Atherosclerosis Disease.
Topics: Arginine; Aspirin; Atherosclerosis; Brain Ischemia; Clopidogrel; Humans; Pipecolic Acids; Platelet Aggregation Inhibitors; Stroke; Sulfonamides; Ticlopidine | 2022 |
Topics: Aspirin; Case-Control Studies; Clopidogrel; Coronary Restenosis; Cytochrome P-450 CYP2C19; Drug-Eluting Stents; Genotype; Humans; Incidence; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Retrospective Studies; Ticlopidine; Treatment Outcome | 2021 |
Platelet function assessed by ROTEM
Topics: Aspirin; Clopidogrel; Deamino Arginine Vasopressin; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Vascular Surgical Procedures | 2022 |
Associations of CYP2C19 and F2R genetic polymorphisms with platelet reactivity in Chinese ischemic stroke patients receiving clopidogrel therapy.
Topics: Aspirin; Clopidogrel; Cytochrome P-450 CYP2C19; Humans; Ischemic Stroke; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Stroke; Ticlopidine; Treatment Outcome | 2022 |
Clinical and Pharmacological Parameters Determine Relapse During Clopidogrel Treatment of Acute Coronary Syndrome.
Topics: Acute Coronary Syndrome; Aspirin; Calcium Channel Blockers; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Diabetes Mellitus, Type 2; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Recurrence; Retrospective Studies; Ticlopidine; Treatment Outcome | 2022 |
COX-1, COX-2 and CYP2C19 variations may be related to cardiovascular events due to acetylsalicylic acid resistance.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Cyclooxygenase 1; Cyclooxygenase 2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Drug Resistance; Genotype; Humans; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine | 2022 |
Clopidogrel Monotherapy More Effective Than Aspirin to Prevent Coronary Events After PCI With Drug-Eluting Stents.
Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Treatment Outcome | 2022 |
Being Overweight or Obese Is Associated with an Increased Platelet Reactivity Despite Dual Antiplatelet Therapy with Aspirin and Clopidogrel.
Topics: Adenosine; Adenosine Diphosphate; Aspirin; Blood Platelets; Clopidogrel; Humans; Obesity; Overweight; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticagrelor; Ticlopidine | 2023 |
Cost-Effectiveness of Cilostazol Added to Aspirin or Clopidogrel for Secondary Prevention After Noncardioembolic Stroke.
Topics: Aspirin; Cilostazol; Clopidogrel; Cost-Benefit Analysis; Humans; Markov Chains; Platelet Aggregation Inhibitors; Quality-Adjusted Life Years; Secondary Prevention; Stroke; Ticlopidine | 2022 |
Cost-effectiveness of testing for CYP2C19 loss-of-function carriers following transient ischemic attack/minor stroke: A Canadian perspective.
Topics: Aspirin; Canada; Clopidogrel; Cost-Benefit Analysis; Cytochrome P-450 CYP2C19; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Quality of Life; Quality-Adjusted Life Years; Stroke; Ticagrelor; Ticlopidine | 2023 |
Effect of body weight on bleeding events of aspirin in ischemic stroke or transient ischemic attack patients.
Topics: Aspirin; Body Weight; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Ischemic Attack, Transient; Ischemic Stroke; Platelet Aggregation Inhibitors; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Stroke; Ticlopidine; Treatment Outcome | 2022 |
P2Y12 reaction units and ischemic and bleeding events after neuro-endovascular treatment.
Topics: Aspirin; Clopidogrel; Endovascular Procedures; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Purinergic P2Y Receptor Antagonists; Ticlopidine; Treatment Outcome | 2022 |
Aspirin: 1A @ 125.
Topics: Aspirin; Fibrinolytic Agents; Humans; Ticlopidine | 2022 |
Antiplatelet therapy to prevent graft failure after coronary artery bypass graft: aspirin monotherapy for most, DAPT for selected few.
Topics: Aspirin; Coronary Artery Bypass; Drug Therapy, Combination; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2022 |
Relationship between CYP2C19 Polymorphism and Clopidogrel Resistance in Patients with Coronary Heart Disease and Ischemic Stroke in China.
Topics: Aged; Aspirin; Cerebral Infarction; China; Clopidogrel; Coronary Disease; Cytochrome P-450 CYP2C19; Genotype; Humans; Ischemic Stroke; Middle Aged; Polymorphism, Genetic; Ticlopidine | 2022 |
Comparison of Cilostazol versus Clopidogrel in Addition to Aspirin in Patients with Ischemic Stroke who Underwent Intracranial or Extracranial Artery Stent Implantation.
Topics: Arteries; Aspirin; Cilostazol; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Ischemic Stroke; Platelet Aggregation Inhibitors; Retrospective Studies; Stents; Stroke; Tetrazoles; Ticlopidine; Treatment Outcome | 2023 |
High On-Treatment Platelet Reactivity: Aspirin versus Clopidogrel.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Platelets; Clopidogrel; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Retrospective Studies; Ticlopidine | 2023 |
Long-Term P2Y
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Ticlopidine; Treatment Outcome | 2023 |
The impact of high on-treatment platelet reactivity and fibrinogen levels on ischemic events in patients with ST elevation myocardial infarction: a prospective observational study.
Topics: Adenosine; Aspirin; Clopidogrel; Fibrinogen; Humans; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; ST Elevation Myocardial Infarction; Ticagrelor; Ticlopidine; Treatment Outcome | 2023 |
High-on-treatment platelet reactivity predicts adverse outcome after carotid artery stenting: A prospective study.
Topics: Aspirin; Blood Platelets; Carotid Arteries; Carotid Stenosis; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Stents; Ticlopidine; Treatment Outcome | 2023 |
The Effectiveness of Antiplatelet Therapy and the Factors Influencing It in Patients with Acute Coronary Syndrome before and during the COVID-19 Pandemic.
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Clopidogrel; COVID-19; Drug Therapy, Combination; Humans; Male; Pandemics; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Ticagrelor; Ticlopidine; Treatment Outcome | 2022 |
Time Course of Death After Acute Coronary Syndrome Treated With Dual Antiplatelet Therapy for 1 Year.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticagrelor; Ticlopidine; Treatment Outcome | 2023 |
Impact of continued clopidogrel use on outcomes of patients undergoing carotid endarterectomy.
Topics: Aged; Aspirin; Carotid Stenosis; Clopidogrel; Endarterectomy, Carotid; Female; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Risk Factors; Stroke; Ticlopidine; Treatment Outcome; Warfarin | 2023 |
Atorvastatin Effect on Clopidogrel Efficacy in Patients with Peripheral Artery Disease.
Topics: Anticoagulants; Aspirin; Atorvastatin; Clopidogrel; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine; Treatment Outcome; Venous Thromboembolism | 2023 |
Risk factors for gastrointestinal bleeding in patients with cerebral infarction after dual antiplatelet therapy.
Topics: Aspirin; Cerebral Infarction; Clopidogrel; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Hypertension; Peptic Ulcer; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Ticlopidine | 2023 |
Differential inhibition of platelet function by cilostazol in combination with clopidogrel.
Topics: Aspirin; Cilostazol; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Tetrazoles; Ticlopidine | 2023 |
Comparative effectiveness of dual antiplatelet therapy versus monotherapy in patients with ischemic stroke.
Topics: Aspirin; Clopidogrel; Cross-Sectional Studies; Drug Therapy, Combination; Humans; Ischemic Stroke; Platelet Aggregation Inhibitors; Retrospective Studies; Stroke; Ticlopidine; Treatment Outcome | 2023 |
Consider aspirin bridging for non-cardiac surgery in patients with coronary stents treated with oral anticoagulation monotherapy.
Topics: Anticoagulants; Aspirin; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stents; Ticlopidine | 2023 |