Compounds > ticlopidine
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ticlopidine and amlodipine

ticlopidine has been researched along with amlodipine in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (23.53)29.6817
2010's13 (76.47)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Ahn, YK; Bae, Y; Cho, JG; Cho, JH; Jeong, MH; Kang, JC; Kang, KT; Kim, KH; Kim, NH; Kim, SH; Lee, SH; Park, JC; Rhew, JY1
Barnett, PG; Boden, WE; Bowen, J; Deaton, C; Dunbar, SB; Goeree, R; Hartigan, PM; Jurkovitz, C; Kaufman, S; Kolm, P; Lewis, C; Mancini, GB; Maron, DJ; O'Rourke, RA; Spertus, JA; Teo, KK; Veledar, E; Weintraub, WS; Zhang, W; Zhang, Z1
Baltatzi, M; Chatzinikolaou, A; Girtovitis, F; Hatzitolios, A; Ioannidis, G; Kaiafa, G; Ntaios, G; Papadopoulos, A1
Breet, NJ; de Boer, A; Deneer, VH; Hackeng, CM; Harmsze, AM; Klungel, OH; Robijns, K; Ruven, HJ; Ten Berg, JM; van Werkum, JW1
Baron, JA; Bøtker, HE; Jensen, LO; Johansen, MB; Kaltoft, A; Maeng, M; Robertson, DJ; Schmidt, M; Sørensen, HT; Tilsted, HH1
Kang, HJ; Kang, J; Kim, HS; Koo, BK; Lee, HY; Oh, BH; Park, JJ; Park, KW; Park, YB; Yang, HM1
Chan, FK; Chan, K; Lau, YK; Li, AY; Ng, FH; Tunggal, P1
Flockhart, DA; Kreutz, RP1
Lin, L; Lin, S; Liu, XQ; Qiu, LL; Xu, HM; Zhang, J; Zhao, YY; Zou, JJ1
Harada-Shiba, M; Masuo, Y; Ogura, M; Suzuki, H; Takada, T; Yamamoto, H; Yamanashi, Y1

Reviews

1 review(s) available for ticlopidine and amlodipine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for ticlopidine and amlodipine

ArticleYear
Effect of PCI on quality of life in patients with stable coronary disease.
    The New England journal of medicine, 2008, Aug-14, Volume: 359, Issue:7

    Topics: Adrenergic beta-Antagonists; Amlodipine; Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; Calcium Channel Blockers; Clopidogrel; Combined Modality Therapy; Coronary Disease; Cross-Over Studies; Drug Therapy, Combination; Female; Health Status; Humans; Isosorbide Dinitrate; Male; Metoprolol; Middle Aged; Patient Satisfaction; Platelet Aggregation Inhibitors; Quality of Life; Stents; Surveys and Questionnaires; Ticlopidine; Vasodilator Agents

2008
Effect of amlodipine on platelet inhibition by clopidogrel in patients with ischaemic heart disease: a randomised, controlled trial.
    Heart (British Cardiac Society), 2013, Volume: 99, Issue:7

    Topics: Aged; Aged, 80 and over; Amlodipine; Calcium Channel Blockers; Chi-Square Distribution; Clopidogrel; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Female; Hong Kong; Humans; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Risk Assessment; Risk Factors; Ticlopidine; Time Factors

2013

Other Studies

14 other study(ies) available for ticlopidine and amlodipine

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Glutathione; Pharmacology; Sulfur Radioisotopes

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Successful management of intractable coronary spasm with a coronary stent.
    Japanese circulation journal, 2000, Volume: 64, Issue:11

    Topics: Adult; Amlodipine; Aspirin; Calcium Channel Blockers; Cardiovascular Agents; Coronary Angiography; Coronary Artery Disease; Coronary Vasospasm; Diltiazem; Doxazosin; Drug Resistance; Drug Therapy, Combination; Ergonovine; Humans; Isosorbide Dinitrate; Male; Myocardial Infarction; Nicorandil; Nitrates; Pyridines; Stents; Ticlopidine; Ventricular Fibrillation

2000
Ticlopidine-induced myelosuppression spontaneously remitted after five years: a possible link with amlodipine coadministration.
    Internal medicine journal, 2009, Volume: 39, Issue:5

    Topics: Amlodipine; Anemia, Aplastic; Drug Therapy, Combination; Female; Humans; Middle Aged; Remission, Spontaneous; Ticlopidine

2009
The use of amlodipine, but not of P-glycoprotein inhibiting calcium channel blockers is associated with clopidogrel poor-response.
    Thrombosis and haemostasis, 2010, Volume: 103, Issue:5

    Topics: Aged; Amlodipine; Angioplasty; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood Platelets; Calcium Channel Blockers; Clopidogrel; Coronary Restenosis; Coronary Thrombosis; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Postoperative Complications; Prospective Studies; Ticlopidine

2010
Use of clopidogrel and calcium channel blockers and risk of major adverse cardiovascular events.
    European journal of clinical investigation, 2012, Volume: 42, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Cardiovascular Diseases; Child; Child, Preschool; Clopidogrel; Cohort Studies; Denmark; Drug Interactions; Felodipine; Female; Humans; Infant; Male; Middle Aged; Platelet Aggregation Inhibitors; Proportional Hazards Models; Risk; Stents; Ticlopidine; Verapamil; Young Adult

2012
Amlodipine, clopidogrel and CYP3A5 genetic variability: effects on platelet reactivity and clinical outcomes after percutaneous coronary intervention.
    Heart (British Cardiac Society), 2012, Volume: 98, Issue:18

    Topics: Aged; Amlodipine; Angioplasty, Balloon, Coronary; Clopidogrel; Cytochrome P-450 CYP3A; Drug Interactions; Female; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Prospective Studies; Stroke; Ticlopidine

2012
Amlodipine--not a significant contributor to clopidogrel non-response?
    Heart (British Cardiac Society), 2013, Volume: 99, Issue:7

    Topics: Amlodipine; Calcium Channel Blockers; Clopidogrel; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Female; Humans; Male; Myocardial Ischemia; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Ticlopidine

2013
Association of the use of amlodipine with clopidogrel response in Chinese patients undergoing percutaneous coronary intervention.
    Die Pharmazie, 2014, Volume: 69, Issue:11

    Topics: Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Aromatase; Asian People; Clopidogrel; Cohort Studies; Drug Interactions; Drug Resistance; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine; Treatment Outcome; Young Adult

2014
VLDL/LDL acts as a drug carrier and regulates the transport and metabolism of drugs in the body.
    Scientific reports, 2017, 04-04, Volume: 7, Issue:1

    Topics: Amlodipine; Animals; Biological Transport; Cholesterol; Drug Carriers; Hyperlipoproteinemia Type II; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Mice; Pharmaceutical Preparations; Protein Binding; Receptors, LDL; Ticlopidine

2017